Hub : Genes

Bbip1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL intron excision ratio chr1_262963794_262964339 0.04 0.03 8.9e-03 0.02 0.02 0.02 0.02 1.4e-03 1.5e-03 1.7e-03 2.2e-03
2 RMTg gene expression Bbip1 0.19 0.12 8.3e-03 0.04 0.05 0.01 0 3.2e-02 2.1e-02 1.6e-01 2.5e-01
3 Liver mRNA stability Bbip1 0.05 0.03 1.1e-03 0.01 0.01 0.01 0.01 7.2e-03 7.0e-03 1.2e-02 1.7e-02
4 Liver gene expression Bbip1 0.22 0.09 0.0e+00 0.15 0.18 0.18 0.18 2.9e-16 2.1e-19 2.8e-19 7.8e-20
5 PL mRNA stability Bbip1 0.08 0.04 2.8e-07 0.06 0.06 0.06 0.06 1.7e-07 6.0e-07 1.5e-07 3.2e-07
6 Adipose gene expression Bbip1 0.04 0.03 3.4e-04 0.02 0.02 0.03 0.03 1.5e-03 1.7e-03 3.1e-04 4.0e-04
7 NAcc gene expression Bbip1 0.17 0.06 0.0e+00 0.19 0.19 0.2 0.2 1.9e-27 2.2e-28 8.3e-29 8.4e-29
8 IL mRNA stability Bbip1 0.22 0.12 2.7e-04 0.12 0.17 0.13 0.14 1.1e-03 6.7e-05 4.4e-04 2.8e-04
9 IC gene expression Bbip1 0.33 0.14 5.2e-08 0.18 0.16 0.17 0.17 3.5e-08 3.5e-07 1.5e-07 8.5e-08
10 OFC gene expression Bbip1 0.48 0.17 7.7e-07 0.27 0.23 0.22 0.25 3.5e-07 2.8e-06 5.2e-06 1.5e-06
11 Brain gene expression Bbip1 0.2 0.08 0.0e+00 0.24 0.23 0.19 0.23 3.2e-22 5.0e-21 1.2e-17 2.3e-21
12 IC mRNA stability Bbip1 0.15 0.09 5.1e-04 0.08 0.06 0.07 0.07 3.8e-04 1.4e-03 5.7e-04 9.1e-04
13 LHb gene expression Bbip1 0.35 0.13 5.8e-07 0.25 0.2 0.22 0.23 1.3e-06 1.4e-05 5.8e-06 4.0e-06
14 LHb mRNA stability Bbip1 0.19 0.11 1.4e-03 0.11 0.07 0.05 0.05 1.4e-03 7.5e-03 2.8e-02 2.5e-02
15 Brain mRNA stability Bbip1 0.04 0.02 2.0e-03 0.03 0.02 0.01 0.02 3.5e-04 8.4e-03 6.6e-02 2.4e-03
16 pVTA mRNA stability Bbip1 0.09 0.04 3.3e-09 0.1 0.12 0.11 0.12 1.2e-08 8.5e-10 2.3e-09 1.4e-09
17 BLA mRNA stability Bbip1 0.18 0.1 1.2e-06 0.13 0.14 0.1 0.11 2.8e-07 1.2e-07 4.2e-06 1.3e-06
18 BLA gene expression Bbip1 0.32 0.11 2.6e-15 0.26 0.29 0.29 0.28 2.8e-14 6.6e-16 1.1e-15 6.5e-15
19 IL gene expression Bbip1 0.25 0.12 9.0e-05 0.18 0.16 0.18 0.17 3.5e-05 1.2e-04 4.6e-05 8.1e-05
20 PL gene expression Bbip1 0.26 0.08 0.0e+00 0.32 0.33 0.33 0.33 4.6e-35 5.4e-37 1.1e-36 2.0e-36
21 pVTA gene expression Bbip1 0.31 0.09 0.0e+00 0.29 0.32 0.33 0.33 7.6e-24 9.4e-27 4.7e-27 4.0e-27

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density0.71.25.01.82.22.01.81.21.21.1-0.50.90.80.90.80.80.90.7-0.20.40.30.70.40.1
Area under the delay curve0.91.04.21.02.11.71.71.70.91.0-0.50.70.60.70.70.70.80.6-0.30.40.40.80.40.3
BMI with tail2.17.120.84.63.93.83.62.93.02.70.92.62.72.62.32.12.52.21.21.41.42.71.91.3
BMI without tail1.75.19.12.13.02.62.82.42.62.51.12.32.42.42.32.22.42.11.41.91.92.52.01.7
Body weight2.510.937.16.14.85.34.73.44.13.20.93.02.93.02.82.73.02.81.21.41.33.02.21.2
Weight adjusted by age0.60.92.51.30.31.41.11.60.61.00.71.10.91.11.11.30.80.70.70.70.50.70.80.5
Bone surface0.20.41.31.11.20.80.60.30.90.70.20.70.70.70.70.70.70.60.30.40.50.40.50.3
Bone volume0.81.55.82.42.02.21.81.21.51.2-0.11.00.91.00.90.91.00.90.10.40.30.80.60.0
Breakpoint value in progressive ratio session0.40.42.90.61.71.21.10.10.90.6-0.50.30.20.30.30.60.40.5-0.40.30.30.30.2-0.1
Number of licking bursts0.40.71.71.20.70.90.4-0.80.1-0.5-1.2-0.6-0.8-0.6-0.7-0.7-0.7-0.6-1.2-1.1-1.1-0.4-0.9-1.3
Context. condit. distance diff. score0.60.82.7-1.3-1.3-1.6-1.3-1.0-0.8-0.9-0.0-0.8-0.8-0.8-0.7-0.8-0.8-0.8-0.2-0.5-0.4-0.7-0.6-0.3
Locomotion velocity, session 12.42.63.7-0.7-1.1-0.9-1.2-0.8-1.8-1.8-1.7-1.8-1.6-1.8-1.9-1.9-1.8-1.8-1.7-1.7-1.7-1.7-1.8-1.6
Locomotion distance, session 10.20.30.6-0.4-0.7-0.7-0.7-0.8-0.4-0.70.0-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.1-0.4-0.3-0.4-0.4-0.5
Locomotion velocity, session 20.30.31.4-0.3-1.0-0.7-0.5-0.60.30.21.20.40.50.40.50.50.40.21.00.40.50.20.60.5
Locomotion distance, session 20.40.62.51.60.10.4-0.2-0.8-0.0-0.6-0.5-0.6-0.4-0.6-0.6-0.6-0.5-0.7-0.6-1.1-1.0-0.7-0.7-1.2
Locomotion velocity, session 31.21.42.0-0.4-1.4-1.1-1.2-0.8-1.1-1.4-0.6-1.4-1.4-1.4-1.3-1.4-1.4-1.2-0.8-1.3-1.2-1.1-1.2-1.2
Locomotion distance, session 32.32.54.8-0.8-2.2-1.3-1.6-1.0-0.9-1.9-0.8-1.8-1.8-1.8-1.7-1.7-1.8-1.7-1.1-1.7-1.6-1.7-1.6-2.0
Stereotopy head waving bouts, day 30.10.10.50.50.4-0.1-0.20.4-0.30.20.20.20.20.20.30.20.20.20.20.20.20.20.20.7
Stereotopy head waving duration, day 30.10.11.0-0.20.2-0.5-0.50.1-1.0-0.2-0.3-0.2-0.2-0.2-0.2-0.3-0.3-0.1-0.2-0.0-0.0-0.2-0.10.4
Locomotion velocity, session 71.21.42.40.1-0.9-0.5-1.1-0.5-1.0-1.2-1.2-1.2-1.2-1.2-1.2-1.4-1.2-1.5-1.2-1.5-1.5-1.4-1.4-1.2
Locomotion distance, session 71.11.42.7-0.3-1.5-1.4-1.6-1.4-0.9-1.4-0.4-1.3-1.2-1.3-1.2-1.4-1.3-1.3-0.6-1.3-1.1-1.2-1.1-1.2
Stereotopy head waving bouts, day 70.70.81.20.1-0.6-0.6-0.9-0.3-1.1-1.0-0.8-1.0-0.9-1.0-1.1-1.0-1.0-1.0-0.9-1.1-1.1-1.1-1.0-0.8
Stereotopy head waving duration, day 70.50.61.10.6-0.0-0.0-0.30.2-1.1-0.7-1.0-0.8-0.8-0.8-0.9-0.9-0.8-0.8-1.0-1.0-1.0-0.9-0.9-0.7
Locomotion velocity, session 80.10.10.5-0.2-0.7-0.6-0.5-0.6-0.3-0.30.2-0.2-0.2-0.2-0.2-0.3-0.2-0.40.1-0.2-0.1-0.2-0.10.1
Locomotion distance, session 80.40.61.5-0.6-1.2-1.1-1.0-1.2-0.3-0.90.0-0.7-0.8-0.7-0.6-0.7-0.7-0.8-0.2-0.7-0.5-0.7-0.6-0.7
Degree of sensitization distance0.10.10.7-0.20.8-0.0-0.10.1-0.20.40.00.40.50.40.40.20.40.30.10.50.50.20.30.7
Degree of sensitization stereotypy1.51.62.40.3-0.6-0.7-1.0-0.9-1.4-1.4-1.2-1.3-1.3-1.3-1.5-1.4-1.4-1.4-1.3-1.5-1.5-1.5-1.4-1.3
Conditioned locomotion0.70.81.40.5-1.0-0.6-0.9-1.0-0.5-1.0-0.3-0.9-0.9-0.9-0.8-1.0-0.8-1.0-0.5-1.2-1.1-1.1-0.9-1.1
Cocaine response after cond. corrected0.60.84.1-2.0-1.2-2.0-1.4-1.0-0.7-0.50.7-0.4-0.5-0.4-0.3-0.3-0.4-0.00.50.40.5-0.10.20.7
Cocaine response after cond. not corrected1.11.36.7-2.1-1.6-2.6-2.0-1.8-1.2-0.90.7-0.7-0.8-0.7-0.6-0.5-0.7-0.40.40.10.2-0.4-0.10.5
Cocaine response before conditioning0.30.31.70.1-0.4-0.7-0.8-1.3-0.8-0.6-0.2-0.4-0.6-0.4-0.5-0.5-0.4-0.6-0.3-0.6-0.5-0.4-0.5-0.4
Saline control response0.50.62.4-0.4-1.3-1.6-1.5-1.1-1.1-0.80.3-0.5-0.7-0.5-0.6-0.7-0.5-0.60.1-0.4-0.4-0.8-0.40.0
Bone: connectivity density0.40.60.8-0.20.90.50.80.60.90.90.30.90.90.90.90.90.90.70.50.90.90.70.70.7
Bone: cortical apparent density0.70.98.3-1.5-2.9-1.6-1.2-0.2-0.4-0.80.9-0.5-0.6-0.5-0.6-0.6-0.5-0.50.7-0.1-0.2-0.4-0.1-0.1
Bone: cortical area1.11.78.62.91.00.4-0.5-1.6-0.5-1.0-1.1-1.0-1.1-1.0-1.0-1.0-1.0-1.0-1.3-1.9-1.7-1.2-1.3-1.6
Bone: cortical porosity0.10.11.40.61.20.20.1-0.2-0.40.2-0.40.10.10.10.10.10.10.2-0.3-0.00.0-0.2-0.00.2
Bone: cortical porosity0.20.31.70.91.30.60.3-0.2-0.4-0.0-0.8-0.2-0.3-0.2-0.2-0.2-0.2-0.1-0.8-0.4-0.4-0.4-0.4-0.3
Bone: cortical thickness1.21.95.32.3-0.4-0.7-1.3-2.0-0.8-1.5-0.6-1.2-1.4-1.2-1.2-1.2-1.2-1.3-0.9-2.0-1.7-1.4-1.3-1.6
Bone: cortical thickness0.70.83.71.9-0.4-0.4-0.8-1.8-0.1-0.90.1-0.7-0.8-0.7-0.7-0.7-0.7-0.6-0.2-1.3-1.0-0.7-0.7-1.0
Bone: cortical tissue density0.60.98.0-1.6-2.8-1.6-1.2-0.1-0.4-0.70.9-0.4-0.5-0.4-0.5-0.5-0.4-0.40.7-0.0-0.1-0.3-0.1-0.0
Condit. Reinf. active minus inactive responses2.12.44.0-1.4-0.9-1.1-1.3-1.3-2.0-1.6-1.6-1.6-1.6-1.6-1.7-1.8-1.6-1.8-1.6-1.5-1.4-1.5-1.7-1.3
Condit. Reinf. active-inactive response ratio1.01.03.0-1.7-0.4-1.1-1.0-0.6-1.6-1.0-1.0-1.0-1.0-1.0-1.1-1.1-1.0-1.0-1.0-0.6-0.6-0.8-0.9-0.5
Condit. Reinf. active responses3.13.85.5-0.4-0.5-0.9-1.3-2.0-2.3-2.0-2.3-2.1-2.0-2.1-2.2-2.3-2.1-2.2-2.3-2.2-2.1-1.9-2.2-1.9
Condit. Reinf. inactive responses1.21.42.81.20.60.3-0.3-1.7-0.9-1.0-1.5-1.1-1.1-1.1-1.2-1.2-1.2-1.2-1.5-1.5-1.5-1.1-1.3-1.3
Incentive salience index mean2.53.14.4-1.9-1.2-1.3-1.4-1.4-2.1-1.8-1.8-1.9-1.9-1.9-1.9-2.1-1.9-2.0-1.8-1.6-1.6-1.7-1.9-1.5
Condit. Reinf. lever presses0.91.31.9-1.4-0.7-0.4-0.5-0.8-0.9-1.1-1.4-1.2-1.3-1.2-1.2-1.3-1.2-1.2-1.3-1.0-1.1-1.0-1.2-1.3
Condit. Reinf. active minus inactive responses5.67.212.5-1.0-0.8-1.0-1.8-1.4-2.9-2.7-3.5-3.0-2.9-3.0-2.9-2.8-3.1-3.0-3.5-2.8-3.0-2.9-3.2-2.6
Condit. Reinf. active-inactive response ratio4.55.27.5-1.6-0.9-1.6-2.0-1.5-2.7-2.4-2.7-2.5-2.4-2.5-2.4-2.4-2.5-2.6-2.7-2.2-2.2-2.4-2.5-1.9
Condit. Reinf. active responses4.46.110.9-0.3-0.5-0.6-1.3-1.4-2.5-2.5-3.3-2.8-2.6-2.8-2.7-2.6-2.8-2.7-3.3-2.8-2.9-2.6-2.9-2.5
Condit. Reinf. inactive responses0.70.91.90.7-0.10.50.1-0.3-0.6-0.8-1.4-1.0-0.9-1.0-1.0-1.0-1.0-1.0-1.4-1.2-1.4-1.1-1.2-1.3
Condit. Reinf. lever presses4.15.67.5-0.3-1.0-1.0-1.6-2.0-2.4-2.5-2.6-2.7-2.5-2.7-2.7-2.6-2.7-2.5-2.7-2.7-2.7-2.4-2.7-2.5
Condit. Reinf. lever reinforcers received4.46.110.5-0.5-0.6-0.8-1.6-1.6-2.6-2.5-3.2-2.8-2.6-2.8-2.7-2.6-2.8-2.8-3.2-2.7-2.8-2.6-2.9-2.4
Conditioned reinforcement - actives0.20.42.10.71.41.10.80.50.80.6-0.60.60.40.70.20.20.60.2-0.30.30.20.00.20.4
Conditioned reinforcement - inactives0.50.71.80.90.40.6-0.10.2-0.7-0.6-1.3-0.7-0.8-0.6-0.9-0.9-0.6-0.8-1.2-1.0-1.0-1.0-1.0-1.0
Conditioned locomotion2.22.94.91.51.41.92.02.22.21.81.11.82.01.91.61.61.81.41.31.51.41.71.61.5
Patch foraging indifference point 0 sec0.30.66.22.51.5-0.5-0.9-1.5-0.20.10.70.30.10.30.30.40.40.30.5-0.20.20.00.30.6
Patch foraging indifference point AUC1.31.93.51.50.30.2-0.6-1.8-0.9-1.2-1.5-1.3-1.3-1.3-1.2-1.2-1.4-1.3-1.6-1.9-1.7-1.4-1.6-1.9
Delay disc. indifference point, 0s delay0.80.85.21.51.21.61.32.31.10.8-0.20.60.50.60.60.70.60.5-0.10.30.10.60.30.1
Delay disc. indifference point, 16s delay0.30.31.90.41.40.90.91.00.00.5-0.50.40.40.40.40.30.50.2-0.30.30.20.50.10.3
Delay disc. indifference point, 2s delay0.20.21.20.40.41.01.01.10.50.4-0.30.10.10.10.20.30.10.4-0.20.0-0.10.20.0-0.3
Delay disc. indifference point, 24s delay0.70.84.71.12.21.71.61.60.60.7-0.90.40.50.40.40.50.50.4-0.70.10.10.20.0-0.3
Delay disc. indifference point, 4s delay0.20.20.9-0.10.70.90.80.9-0.00.0-1.0-0.2-0.1-0.2-0.2-0.2-0.1-0.3-0.8-0.3-0.3-0.0-0.4-0.5
Delay disc. indifference point, 8s delay1.21.46.71.72.62.02.01.51.41.1-0.40.90.70.90.90.90.90.8-0.20.50.51.10.50.5
Indifference point function ln k0.20.30.8-0.7-0.4-0.40.00.90.10.40.70.50.20.50.30.20.50.50.60.70.60.60.50.9
Indifference point function log k0.20.30.8-0.7-0.4-0.40.00.90.10.40.70.50.20.50.30.20.50.50.60.70.60.60.50.9
Patch foraging total patch changes 0 sec0.30.67.22.71.5-0.3-0.8-1.4-0.2-0.10.30.1-0.10.10.00.10.20.10.1-0.5-0.2-0.3-0.00.2
Patch foraging total patch changes 12 sec0.70.93.21.81.00.2-0.5-1.6-0.6-0.7-0.9-0.8-0.8-0.8-0.7-0.5-0.8-0.6-1.0-1.2-1.0-1.1-0.9-1.2
Patch foraging total patch changes 18 sec1.32.08.52.91.30.3-0.8-1.3-1.1-1.1-1.6-1.1-1.3-1.1-1.1-1.0-1.1-1.2-1.7-2.0-1.8-1.5-1.5-1.5
Patch foraging total patch changes 24 sec0.71.25.12.31.90.70.0-1.6-0.4-0.5-1.3-0.7-0.7-0.7-0.6-0.5-0.7-0.6-1.3-1.3-1.0-0.8-0.9-1.1
Patch foraging total patch changes 6 sec0.50.77.52.71.80.1-0.4-1.80.2-0.00.10.00.00.00.20.20.10.1-0.0-0.6-0.2-0.3-0.1-0.2
Patch foraging time to switch 0 sec0.71.43.2-1.80.1-0.10.51.10.81.21.11.21.11.21.11.21.11.11.21.71.61.11.31.5
Patch foraging water rate 0 sec0.30.64.12.00.30.4-0.1-0.4-0.1-0.6-0.7-0.6-0.6-0.6-0.6-0.8-0.6-0.7-0.8-1.2-1.1-0.7-0.8-0.9
Patch foraging water rate 12 sec0.40.72.51.61.51.11.01.40.80.80.00.90.70.90.80.60.90.60.10.30.30.60.50.4
Patch foraging water rate 18 sec0.30.50.80.30.60.30.60.80.70.70.60.70.90.70.60.50.70.80.70.70.70.80.70.8
Patch foraging water rate 24 sec0.50.72.81.71.51.11.11.01.10.70.30.60.50.60.70.60.60.80.30.30.41.00.60.5
Patch foraging water rate 6 sec0.50.72.91.70.70.70.51.01.00.80.70.81.00.80.90.80.90.60.70.50.50.60.70.8
Seeking ratio, delayed vs. immediate footshock0.60.71.40.80.60.50.81.11.20.81.00.80.80.80.80.70.90.80.90.70.81.00.90.7
Distance traveled before self-admin0.60.87.9-1.2-2.8-1.2-1.50.0-0.3-0.70.9-0.7-0.2-0.6-0.4-0.3-0.8-0.30.7-0.2-0.3-0.6-0.1-0.5
Distance traveled after self-admin1.01.34.1-0.0-0.9-0.00.11.01.40.92.01.01.01.01.11.21.01.21.81.21.11.01.40.9
Extensor digitorum longus weight0.52.15.81.7-0.21.70.80.2-0.2-0.9-1.9-1.2-1.3-1.2-1.3-1.3-1.2-1.3-1.9-1.9-2.1-1.2-1.6-2.4
Bone: elastic displacement0.00.00.2-0.50.30.20.20.4-0.30.2-0.10.10.10.10.20.20.10.2-0.10.30.20.10.10.2
Bone: elastic work0.40.51.10.70.30.80.81.10.60.80.70.70.60.70.80.90.80.90.70.60.50.80.70.5
Bone: endosteal estimation1.02.28.31.92.92.22.00.71.51.60.21.31.31.31.41.41.31.70.41.01.01.51.10.8
Bone: endosteal perimeter0.51.05.62.41.81.91.40.41.40.8-0.20.60.60.60.60.60.60.6-0.1-0.00.00.50.3-0.3
Epididymis fat weight1.03.315.74.03.23.82.82.10.70.5-2.30.10.10.1-0.3-0.20.1-0.2-2.0-1.2-1.40.4-0.9-1.3
Delta time in closed arm before/after self-admin0.60.61.6-0.6-0.2-0.7-0.50.10.10.41.20.50.80.50.71.00.60.81.11.01.10.40.91.0
Delta time in open arm before/after self-admin0.30.31.41.20.81.00.60.9-0.00.0-0.9-0.2-0.3-0.1-0.2-0.4-0.1-0.2-0.8-0.5-0.6-0.2-0.4-0.5
Diff in mean of infusions in LGA sessions2.22.75.6-2.2-1.9-2.4-1.9-1.9-1.5-2.0-0.8-1.9-1.7-1.9-1.9-1.6-1.8-1.3-1.0-1.2-1.1-1.0-1.4-1.0
Delay discount exponential model param0.80.94.0-1.1-2.0-1.8-1.7-1.6-0.8-0.90.6-0.6-0.5-0.6-0.6-0.6-0.7-0.50.4-0.3-0.2-0.7-0.2-0.1
Extinction: sum of active levers before priming0.50.51.10.50.50.1-0.2-1.0-0.8-0.6-1.0-0.8-1.0-0.7-0.7-0.6-0.7-0.5-1.0-0.8-0.7-0.6-0.8-0.8
Active lever presses in extinction session 60.30.30.70.5-0.30.1-0.30.5-0.3-0.5-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.5-0.6-0.7-0.7-0.7-0.6-0.9
Bone: final force0.30.53.11.81.50.60.6-0.70.50.50.50.60.40.60.60.50.60.70.40.10.40.80.50.3
Bone: final moment0.50.73.82.01.80.90.9-0.50.60.70.40.70.50.70.70.70.70.90.40.20.50.90.60.4
Food consumed during 24 hour testing period0.50.71.20.20.90.70.80.61.11.00.41.10.81.11.01.01.10.70.50.80.80.60.70.6
Glucose1.52.35.71.81.02.42.41.82.41.60.91.41.61.41.31.41.41.51.01.00.91.61.30.5
Heart weight3.04.77.30.7-1.4-2.1-2.7-2.5-2.3-2.6-1.3-2.3-2.2-2.3-2.4-2.4-2.3-2.1-1.6-2.5-2.3-2.3-2.2-1.8
Delay discount hyperbolic model param0.70.83.0-0.9-1.7-1.7-1.7-1.6-0.8-0.80.6-0.6-0.5-0.6-0.6-0.6-0.6-0.50.4-0.2-0.2-0.7-0.2-0.0
Intermittent access intake day 1-15 change1.22.55.91.32.42.02.02.01.91.80.51.71.51.51.51.51.71.60.71.41.31.21.41.4
Intermittent access intake escalation1.02.15.01.52.22.01.91.91.61.70.41.51.31.31.31.41.41.50.61.21.11.11.21.2
Intermittent access intake escalation 22.22.54.81.32.22.12.21.71.91.80.61.71.61.51.41.51.61.70.81.41.31.31.41.3
Intermitt. access day 1 inactive lever presses0.31.25.82.41.62.21.70.70.3-0.0-1.3-0.6-0.4-0.4-0.3-0.2-0.4-0.1-1.3-1.0-1.10.2-0.7-1.5
Intermitt. access day 15 inactive lever presses0.00.11.0-1.00.20.10.4-0.0-0.10.0-0.1-0.10.0-0.1-0.00.1-0.10.1-0.10.30.30.60.1-0.0
Intermitt. access escalation Index0.91.32.50.80.91.10.91.01.61.31.11.41.21.21.41.31.01.41.11.11.10.61.20.7
Intermittent access day 1 total infusions0.20.41.40.80.80.80.40.4-0.1-0.3-1.2-0.4-0.5-0.4-0.4-0.4-0.5-0.5-1.1-0.6-0.7-0.5-0.7-0.7
Intermittent access day 15 total infusions0.40.62.90.91.61.71.41.50.50.5-1.00.20.00.10.10.10.20.2-0.8-0.0-0.20.1-0.1-0.2
Intermittent access terminal intake (last 3 days)0.91.24.40.81.82.02.11.81.31.0-0.40.80.70.70.60.60.70.9-0.10.70.51.10.60.5
Intermittent access total infusions0.60.83.71.41.71.91.61.40.70.5-0.90.30.20.30.10.20.20.2-0.70.0-0.10.4-0.0-0.1
Intermittent access day 1 locomotion0.10.10.50.0-0.30.40.50.70.20.20.30.10.10.20.30.30.10.40.30.20.10.70.30.2
Intermittent access day 15 total locomotion0.40.73.01.70.91.61.21.70.80.7-0.00.70.60.70.50.50.70.50.10.20.10.40.40.2
Intermittent access total locomotion1.21.43.51.10.61.31.41.91.31.11.01.11.21.11.11.21.01.31.11.00.91.31.21.0
Intermittent access standard deviation0.71.55.71.22.42.01.61.41.61.3-0.41.21.31.20.80.81.20.8-0.00.80.80.60.70.6
Left kidney weight2.310.914.82.62.62.12.62.43.83.43.53.53.53.53.63.83.43.93.53.13.33.73.63.2
Right kidney weight1.57.010.92.92.42.12.42.03.32.62.62.72.82.62.82.92.52.92.62.32.43.22.72.4
Cocaine induced anxiety0.60.83.3-1.6-1.7-1.8-1.2-1.6-0.4-0.41.40.0-0.0-0.00.00.1-0.00.21.20.30.60.30.40.5
Post-drug Anxiety1.31.33.4-0.3-1.2-1.7-1.7-1.9-0.9-1.4-0.1-1.2-1.1-1.3-1.1-1.1-1.3-0.9-0.4-1.2-0.9-0.9-0.9-0.9
Baseline Anxiety2.73.27.01.10.50.4-0.40.0-1.1-1.6-2.6-1.9-1.7-1.9-1.7-2.0-2.0-1.9-2.6-2.2-2.3-1.8-2.2-2.2
Tail length0.10.52.00.60.71.41.10.91.30.7-0.10.50.40.50.70.70.60.60.00.30.20.20.3-0.1
Length with tail0.41.810.03.21.72.72.01.02.01.10.10.90.70.91.01.10.91.10.10.0-0.00.70.5-0.3
Length without tail0.82.725.95.12.33.42.20.61.70.6-0.80.40.20.40.20.30.20.4-0.8-1.1-1.10.1-0.3-1.3
Times rat made contact with spout0.40.44.82.20.50.90.4-0.30.6-0.1-0.3-0.1-0.1-0.10.0-0.2-0.1-0.3-0.4-0.8-0.7-0.2-0.4-0.7
Lifetime Intake0.60.73.11.51.81.71.31.40.60.4-1.00.20.30.2-0.00.00.20.0-0.8-0.1-0.2-0.0-0.1-0.2
Liver weight, left0.50.84.02.01.71.41.11.01.30.80.10.70.60.60.90.70.60.60.10.10.20.50.40.1
Liver weight, right4.98.515.83.63.04.03.63.83.83.11.62.92.92.83.03.02.82.91.82.11.92.72.51.6
Locomotor activity0.10.21.11.1-0.6-0.7-0.6-0.6-0.1-0.10.90.20.10.20.1-0.00.30.00.7-0.1-0.00.10.20.3
Locomotor testing distance0.40.72.90.8-0.8-1.0-0.7-0.60.30.21.70.70.60.70.50.40.70.51.50.50.60.60.81.1
Locomotor testing rearing0.71.42.90.50.4-0.4-0.00.30.81.01.71.41.31.41.21.11.41.21.71.31.41.01.41.6
Locomotion in novel chamber0.40.51.7-0.5-1.3-1.3-1.10.3-0.40.11.20.40.30.40.60.40.4-0.01.00.50.50.10.50.9
Locomotion in novel chamber post-restriction0.10.11.2-1.1-0.8-0.40.00.1-0.0-0.20.1-0.3-0.4-0.3-0.2-0.2-0.3-0.10.10.10.10.50.00.3
Fecal boli incidents, locomotor time 10.20.41.00.20.60.91.0-0.20.70.70.30.60.80.60.60.60.50.80.30.60.50.50.50.3
Change in fecal boli incidents, locomotor task1.01.03.5-1.9-1.3-0.8-0.70.0-0.9-1.0-0.9-1.1-1.0-1.1-1.0-1.0-1.1-0.9-0.9-0.7-0.8-0.8-0.9-0.8
Time >=10cm from walls, locomotor time 10.60.61.3-0.60.0-0.4-0.00.01.10.80.90.91.00.90.90.70.90.51.01.01.00.20.80.9
Bouts of movement, locomotor time 10.60.73.21.21.81.71.21.70.40.6-1.10.30.40.30.20.20.30.0-0.80.1-0.20.1-0.1-0.0
Total resting periods, locomotor time 10.60.73.41.11.71.81.41.50.30.6-1.10.30.40.30.20.20.30.1-0.90.0-0.20.1-0.1-0.2
Rest time, locomotor task time 10.30.40.6-0.1-0.7-0.6-0.7-0.6-0.8-0.7-0.3-0.6-0.4-0.6-0.7-0.7-0.6-0.7-0.4-0.7-0.7-0.7-0.6-0.6
Distance moved, locomotor task time 10.40.51.60.70.71.21.21.30.50.80.20.70.50.70.70.70.70.70.30.50.40.60.50.2
Vertical activity count, locomotor time 10.20.53.6-1.3-1.9-1.2-1.0-0.6-0.1-0.70.4-0.5-0.4-0.5-0.5-0.5-0.6-0.60.2-0.2-0.2-0.4-0.2-0.2
Time >=10cm from walls, locomotor time 20.40.61.30.9-0.5-0.3-0.6-0.7-0.3-0.9-0.5-0.8-0.5-0.8-0.7-0.8-0.7-0.9-0.6-1.1-1.0-0.8-0.9-1.0
Bouts of movement, locomotor time 20.20.32.1-1.2-0.10.50.51.5-1.10.2-0.7-0.1-0.3-0.0-0.1-0.1-0.1-0.2-0.50.30.0-0.1-0.2-0.1
Total resting periods, locomotor time 20.10.31.6-0.80.30.60.71.3-0.70.5-0.40.30.10.30.20.30.20.2-0.30.60.30.10.20.3
Rest time, locomotor task time 21.62.03.40.31.00.30.60.01.51.51.61.71.81.71.61.61.31.61.61.61.71.11.61.7
Distance moved, locomotor task time 20.81.01.90.0-0.1-0.3-0.6-0.0-0.9-1.1-1.2-1.1-1.4-1.1-1.1-1.0-1.0-1.2-1.3-1.2-1.2-1.0-1.2-1.1
Vertical activity count, locomotor time 21.72.43.60.2-1.6-1.2-1.6-1.1-0.8-1.9-0.9-1.7-1.7-1.7-1.7-1.7-1.6-1.7-1.2-1.9-1.9-1.5-1.7-1.7
Light reinforcement 10.61.43.1-1.1-1.5-1.5-1.5-1.8-1.1-1.4-0.4-1.3-0.9-1.3-1.4-1.3-1.4-1.1-0.5-0.9-0.8-1.0-0.9-0.7
Light reinforcement 20.71.02.6-1.2-1.6-1.0-1.0-1.0-1.1-1.1-0.4-1.1-0.9-1.1-1.2-1.1-1.1-1.0-0.6-0.7-0.8-0.9-0.9-0.8
Bone: marrow area1.02.28.22.02.92.22.00.61.51.60.21.31.31.31.41.41.31.70.41.01.01.51.10.8
Bone: maximum diameter1.01.914.03.71.41.20.1-1.0-0.1-0.8-1.3-0.9-0.9-0.9-0.9-0.8-0.9-0.8-1.4-1.9-1.8-1.0-1.2-1.7
Bone: maximum force0.10.22.01.41.10.40.4-0.90.10.20.10.20.00.20.20.20.30.30.0-0.2-0.00.30.10.0
Bone: maximum moment0.20.32.41.61.50.70.6-0.60.20.4-0.00.30.20.30.40.40.40.5-0.1-0.10.10.30.20.1
Mean time between licks in bursts0.10.31.2-0.50.90.30.31.0-0.7-0.1-1.1-0.2-0.2-0.2-0.4-0.3-0.2-0.3-0.9-0.1-0.20.1-0.40.1
Mean num. licks in bursts0.40.71.70.3-0.3-0.3-0.00.80.50.71.30.81.00.81.00.80.90.71.30.90.90.61.01.2
Cd content in liver1.21.34.2-1.0-1.1-2.1-1.4-0.9-0.10.32.00.70.70.70.70.70.70.71.81.11.30.61.11.7
Co content in liver0.60.73.3-1.1-1.3-1.8-1.4-1.2-0.6-0.21.20.20.00.20.20.20.00.21.10.50.60.10.51.0
Cu content in liver0.10.10.20.1-0.00.30.50.20.50.40.30.50.40.50.50.50.30.20.30.40.30.20.30.2
Fe content in liver1.41.74.91.30.2-1.1-1.6-2.2-1.5-1.3-0.9-1.2-1.4-1.2-1.2-1.1-1.3-1.2-1.1-1.6-1.3-1.3-1.2-0.8
K content in liver0.80.73.50.00.61.51.41.91.21.0-0.20.80.70.80.70.70.60.50.00.60.40.40.40.0
Mg content in liver0.20.20.8-0.2-0.10.80.50.80.3-0.1-0.8-0.2-0.3-0.2-0.2-0.3-0.3-0.4-0.7-0.3-0.5-0.5-0.5-0.9
Mn content in liver1.11.21.8-0.5-1.3-0.6-1.0-0.4-0.9-1.2-0.9-1.1-1.2-1.1-1.2-1.2-1.2-1.3-1.0-1.2-1.3-1.3-1.2-1.3
Na content in liver1.21.32.1-1.0-1.0-0.2-0.60.5-1.0-1.1-1.4-1.2-1.1-1.2-1.3-1.3-1.2-1.3-1.4-1.0-1.2-1.4-1.3-1.2
Rb content in liver0.40.41.3-0.90.3-0.8-0.7-1.1-1.1-0.5-0.8-0.5-0.6-0.5-0.5-0.5-0.6-0.7-0.7-0.3-0.2-0.6-0.6-0.1
Se content in liver0.10.10.5-0.7-0.2-0.5-0.4-0.5-0.10.10.30.10.30.10.10.20.10.20.30.40.40.30.30.6
Sr content in liver2.21.96.9-1.4-0.40.30.72.60.71.41.21.31.31.31.31.31.31.31.41.91.61.31.51.8
Zn content in liver0.40.40.9-0.9-0.50.30.50.90.60.70.60.70.60.70.70.60.60.50.70.90.70.40.60.4
Bone: minimum diameter0.30.64.22.01.31.40.80.10.3-0.1-0.9-0.4-0.5-0.4-0.3-0.2-0.3-0.1-0.9-0.8-0.8-0.2-0.5-1.0
Time in familiar zone, hab. session 11.81.83.4-1.3-0.3-0.30.41.40.71.21.71.21.41.21.21.21.21.41.71.81.81.51.61.9
Time in novel zone, hab. session 11.71.74.11.40.30.90.2-0.9-0.5-1.0-1.8-1.2-1.4-1.2-1.1-1.1-1.2-1.2-1.8-1.8-1.8-1.2-1.5-2.0
Total zone transitions, hab. session 10.81.12.41.4-0.4-0.3-0.7-1.2-0.6-1.1-0.6-0.9-0.8-0.9-1.2-1.3-0.9-1.1-0.8-1.5-1.4-1.0-1.1-1.2
Total locomotion distance, hab. session 10.50.81.61.20.10.0-0.3-0.8-0.7-0.8-0.9-0.7-0.8-0.7-0.9-1.0-0.7-0.9-1.0-1.3-1.2-0.9-1.0-1.0
Locomotion velocity, hab. session 10.71.01.90.9-0.1-0.4-0.8-1.1-1.0-1.0-1.0-0.9-1.0-0.9-1.2-1.3-0.9-1.1-1.0-1.4-1.3-1.2-1.1-1.1
Time in familiar zone, hab. session 20.50.62.50.71.51.61.20.80.10.1-1.3-0.3-0.2-0.3-0.2-0.2-0.3-0.1-1.2-0.4-0.5-0.1-0.5-0.8
Time in novel zone, hab. session 20.30.41.3-0.4-1.1-1.1-0.8-0.6-0.10.01.20.30.10.30.30.30.30.31.00.40.50.20.50.7
Total zone transitions, hab. session 20.20.30.91.00.10.2-0.2-0.6-0.2-0.5-0.6-0.5-0.5-0.5-0.5-0.6-0.4-0.5-0.6-0.9-0.8-0.4-0.6-0.7
Total locomotion distance, hab. session 20.50.61.61.30.00.3-0.2-0.4-0.4-0.7-0.8-0.7-0.8-0.7-0.7-0.7-0.6-0.8-0.9-1.2-1.1-0.7-0.9-1.1
Locomotion velocity, hab. session 20.50.71.51.1-0.20.1-0.4-0.5-0.4-0.8-0.7-0.8-0.9-0.8-0.8-0.8-0.7-0.9-0.9-1.2-1.2-0.9-0.9-1.1
Novel to familiar place preference ratio0.10.11.00.31.00.50.60.20.20.4-0.30.30.30.30.40.30.30.2-0.20.20.20.20.10.2
Novelty place preference0.40.41.70.61.31.01.10.70.60.8-0.20.60.50.60.70.60.60.6-0.00.40.40.60.40.3
Time in novel zone, NPP test0.50.52.70.81.61.31.30.80.50.8-0.50.60.50.60.60.60.60.5-0.30.30.30.50.20.2
Total zone transitions, NPP test1.01.43.01.20.00.2-0.5-1.1-0.3-1.2-1.2-1.1-1.0-1.1-1.3-1.4-1.0-1.3-1.3-1.7-1.6-1.2-1.4-1.7
Total locomotion distance, NPP test0.91.32.61.50.10.3-0.4-0.7-0.5-1.0-1.3-1.1-0.9-1.1-1.2-1.2-1.0-1.2-1.3-1.6-1.5-1.3-1.3-1.6
Locomotion velocity, NPP test0.60.81.61.2-0.2-0.0-0.5-0.7-0.3-0.9-0.8-0.8-0.7-0.8-0.9-1.0-0.8-1.0-0.8-1.3-1.2-1.0-1.0-1.2
Intraocular pressure0.40.62.51.11.60.80.2-0.6-0.7-0.3-1.4-0.4-0.5-0.4-0.4-0.4-0.4-0.6-1.3-0.9-0.8-0.6-0.8-0.7
Delta distance traveled before/after self-admin3.33.54.71.02.01.21.61.91.92.01.52.11.92.12.01.92.22.01.61.91.92.01.92.0
Delta ambulatory time before/after self-admin2.22.86.11.32.51.61.91.51.51.90.81.91.51.91.71.61.91.71.01.51.51.81.51.6
Parametrial fat weight1.02.414.13.73.53.22.41.30.70.8-1.50.50.30.50.30.30.50.3-1.2-0.6-0.70.5-0.3-0.6
Pavlov. Cond. lever latency0.20.21.61.31.00.10.1-0.6-0.10.20.30.20.30.20.20.30.20.40.20.10.20.20.30.4
Pavlov. Cond. magazine entry latency0.10.20.70.60.20.80.60.40.2-0.1-0.6-0.2-0.3-0.2-0.2-0.1-0.2-0.2-0.5-0.4-0.5-0.1-0.3-0.6
Pavlov. Cond. change in total contacts0.10.10.6-0.4-0.60.50.50.80.70.10.0-0.0-0.1-0.00.00.0-0.00.10.00.0-0.10.20.0-0.4
Pavlov. Cond. index score0.10.10.50.0-0.40.70.50.70.50.0-0.2-0.1-0.2-0.1-0.1-0.0-0.1-0.1-0.2-0.1-0.30.0-0.2-0.6
Pavlov. Cond. latency score0.10.10.6-0.1-0.40.60.60.80.60.2-0.00.1-0.00.10.10.10.10.1-0.00.1-0.10.20.0-0.4
Pavlov. Cond. lever contacts0.20.21.7-1.3-0.80.20.20.90.1-0.1-0.4-0.2-0.3-0.2-0.2-0.2-0.2-0.2-0.30.1-0.1-0.1-0.2-0.3
Pavlov. Cond. magazine entry number0.40.42.0-1.2-0.5-1.4-1.3-1.0-1.0-0.6-0.0-0.4-0.3-0.4-0.4-0.5-0.5-0.5-0.1-0.2-0.0-0.6-0.30.1
Pavlov. Cond. intertrial magazine entries0.50.62.20.0-0.6-0.8-0.9-1.5-1.0-0.8-0.3-0.9-0.7-0.9-0.8-0.8-0.9-0.7-0.4-0.8-0.7-0.7-0.7-0.7
Pavlov. Cond. lever-magazine prob. diff.0.10.20.60.0-0.50.60.40.60.3-0.2-0.4-0.3-0.4-0.3-0.3-0.2-0.3-0.3-0.4-0.4-0.5-0.2-0.4-0.8
Pavlov. Cond. response bias0.10.10.5-0.3-0.40.50.50.70.40.0-0.3-0.1-0.2-0.1-0.1-0.0-0.1-0.0-0.2-0.0-0.20.1-0.1-0.4
Pavlov. Cond. lever latency4.25.78.2-0.10.40.71.52.42.22.52.82.72.62.72.62.52.62.52.92.92.82.42.82.6
Pavlov. Cond. magazine entry latency0.50.62.91.61.71.50.90.70.40.3-1.0-0.00.1-0.00.00.1-0.00.0-0.9-0.4-0.5-0.1-0.3-0.5
Pavlov. Cond. change in total contacts1.72.76.40.70.70.3-0.5-1.0-1.4-1.4-2.5-1.7-1.6-1.7-1.6-1.6-1.7-1.7-2.5-2.1-2.1-1.7-2.0-1.8
Pavlov. Cond. index score1.41.94.61.11.10.6-0.2-0.9-1.0-1.1-2.2-1.4-1.2-1.4-1.3-1.3-1.4-1.3-2.1-1.8-1.7-1.3-1.6-1.5
Pavlov. Cond. latency score1.11.54.01.31.30.90.1-0.7-0.7-0.8-2.0-1.1-1.0-1.1-1.1-1.0-1.1-1.1-1.9-1.6-1.6-1.1-1.4-1.4
Pavlov. Cond. lever contacts3.44.77.20.3-0.5-0.6-1.3-2.3-1.9-2.3-2.4-2.4-2.3-2.4-2.4-2.3-2.4-2.3-2.5-2.7-2.6-2.1-2.5-2.4
Pavlov. Cond. magazine entry number0.50.62.8-1.5-1.7-1.5-0.9-0.2-0.3-0.11.20.20.10.20.10.10.20.21.10.60.70.20.50.7
Pavlov. Cond. intertrial magazine entries0.50.71.8-0.6-1.2-1.2-1.3-1.2-0.8-0.90.0-0.8-0.8-0.8-0.8-0.8-0.8-0.7-0.2-0.6-0.5-0.8-0.6-0.6
Pavlov. Cond. lever-magazine prob. diff.1.31.74.11.31.00.7-0.1-0.7-0.8-1.0-2.0-1.3-1.1-1.3-1.2-1.2-1.3-1.2-2.0-1.7-1.7-1.2-1.5-1.5
Pavlov. Cond. response bias2.83.86.30.70.2-0.3-1.0-1.7-1.8-2.0-2.5-2.2-2.0-2.2-2.1-2.0-2.2-2.0-2.5-2.4-2.4-1.8-2.3-2.1
Time in closed arm before self-admin0.30.41.1-0.9-1.0-0.10.0-0.4-0.3-0.7-0.5-0.8-0.6-0.8-1.0-0.8-0.6-0.5-0.6-0.6-0.7-0.2-0.6-0.8
Time in closed arm after self-admin0.30.44.7-2.2-0.9-0.8-0.50.2-0.3-0.10.2-0.1-0.0-0.1-0.20.10.10.00.30.60.50.10.20.4
Time in open arm before self-admin0.10.10.30.0-0.4-0.0-0.3-0.5-0.1-0.10.00.0-0.2-0.1-0.00.0-0.2-0.2-0.0-0.2-0.2-0.6-0.2-0.4
Time in open arm after self-admin0.40.53.41.80.70.90.30.3-0.2-0.2-0.9-0.3-0.4-0.3-0.3-0.5-0.4-0.5-0.9-0.9-0.9-0.5-0.6-0.8
Bone: periosteal estimation0.61.210.63.32.41.81.2-0.20.90.7-0.30.50.40.50.50.50.50.7-0.3-0.3-0.20.40.2-0.2
Bone: periosteal perimeter0.71.314.63.82.01.80.9-0.21.00.3-0.50.20.10.20.20.20.20.1-0.5-0.9-0.7-0.1-0.3-0.9
Bone: post-yield work0.60.92.60.20.60.3-0.0-0.2-0.8-0.8-1.6-0.9-1.1-0.9-0.9-0.9-0.9-1.0-1.5-1.1-1.1-0.9-1.2-1.1
Progressive ratio test 1 active lever presses0.50.63.20.91.51.40.91.80.20.3-1.2-0.10.10.0-0.0-0.20.1-0.1-0.9-0.2-0.3-0.2-0.3-0.2
Progressive ratio test 1 breakpoint0.50.63.10.91.51.30.81.80.10.2-1.3-0.2-0.0-0.1-0.1-0.3-0.0-0.2-1.0-0.3-0.4-0.4-0.4-0.3
Progressive ratio test 1 inactive lever presses0.81.13.31.31.81.81.30.9-0.0-0.2-1.8-0.7-0.5-0.5-0.5-0.5-0.6-0.4-1.6-0.9-0.9-0.5-0.9-1.3
Progressive ratio test 2 active lever presses1.41.66.51.52.42.31.92.61.51.2-0.70.90.80.90.70.70.80.7-0.30.60.40.60.50.4
Progressive ratio test 2 breakpoint1.41.66.41.62.42.31.92.51.51.2-0.60.90.80.90.70.80.80.7-0.30.60.40.60.50.4
Progressive ratio test 2 inactive lever presses0.71.25.81.21.92.42.32.10.80.6-1.00.20.20.20.10.30.10.4-0.80.2-0.00.80.1-0.3
Incentive Sensitization - Responses0.71.03.91.41.92.01.51.91.40.9-0.70.80.70.70.50.50.60.4-0.40.40.2-0.00.30.0
Incentive Sensitization - Breakpoint0.81.03.81.31.81.91.51.81.40.9-0.60.80.70.70.50.60.60.5-0.30.40.30.10.30.1
Sum of active levers in priming session hrs 5-60.50.50.90.1-0.20.2-0.20.8-0.1-0.6-0.9-0.7-0.7-0.7-0.7-0.8-0.7-0.7-0.9-0.7-0.8-0.7-0.8-1.0
Progressive ratio0.40.64.0-0.4-0.2-1.1-1.3-2.0-1.2-0.7-0.3-0.6-0.9-0.6-0.4-0.4-0.7-0.5-0.4-0.5-0.3-0.8-0.5-0.5
Food seeking constrained by brief footshock1.01.22.2-0.10.7-0.6-1.0-0.6-0.8-1.1-1.5-1.2-1.5-1.2-1.2-1.2-1.2-0.9-1.5-1.1-1.0-1.1-1.2-1.1
Seeking ratio, punishment vs. effort0.30.42.30.50.21.00.71.50.4-0.1-0.8-0.4-0.2-0.4-0.5-0.5-0.2-0.3-0.7-0.4-0.6-0.1-0.4-0.7
Retroperitoneal fat weight1.66.832.15.04.75.74.94.01.71.7-2.01.00.81.00.91.01.01.2-1.5-0.2-0.61.80.1-0.6
Reaction time number correct1.73.29.61.63.11.62.00.81.92.00.81.92.01.91.91.71.91.91.01.51.71.81.61.5
Reaction time mean minus median0.20.61.01.01.00.50.50.60.40.70.60.60.90.61.01.00.60.80.60.80.70.70.80.9
Reaction time mean minus median AUC0.71.82.90.91.01.01.11.51.41.51.11.41.71.41.71.61.41.41.31.41.31.21.41.5
Reaction time num false alarms1.11.62.8-0.2-0.9-0.2-0.7-1.0-1.0-1.3-1.4-1.3-1.5-1.3-1.4-1.4-1.3-1.5-1.4-1.4-1.5-1.4-1.5-1.7
Reaction time num false alarms AUC1.32.12.7-0.2-1.2-0.8-1.3-1.6-1.3-1.6-1.2-1.5-1.6-1.5-1.6-1.6-1.5-1.6-1.3-1.6-1.6-1.6-1.6-1.6
Reaction time trials correct on left1.73.29.61.63.11.62.00.81.92.00.81.92.01.91.91.71.91.91.01.51.71.81.61.5
Reaction time trials on left1.73.210.01.63.21.62.00.81.92.00.81.92.01.91.91.71.91.91.01.51.71.91.61.6
Reaction time mean0.81.22.00.00.20.20.51.10.91.01.41.11.21.11.31.41.11.11.41.41.31.11.31.3
Reaction time mean AUC0.50.91.6-0.4-0.1-0.10.31.10.60.81.10.91.00.91.11.10.80.81.21.31.11.01.11.2
Median of all reaction times1.11.52.5-0.2-0.00.10.61.21.11.11.61.21.31.21.41.51.21.31.61.51.51.31.51.4
Reaction time omissions0.81.12.4-1.41.50.30.71.30.41.10.30.91.10.91.01.10.91.10.61.51.50.91.01.5
Reaction time false alarm rate3.54.86.4-1.2-2.5-1.4-2.0-1.7-2.2-2.4-1.8-2.4-2.5-2.4-2.4-2.3-2.4-2.5-1.9-2.2-2.4-2.4-2.3-2.3
Reaction time premature initiation rate0.20.31.41.2-0.9-0.2-0.4-1.10.3-0.20.90.1-0.20.10.10.20.0-0.10.7-0.4-0.2-0.10.1-0.4
Reaction time premature initiations0.71.24.92.20.90.60.6-0.61.40.91.41.21.01.21.21.21.11.01.30.50.70.91.00.5
Std. dev. reaction times0.51.01.91.11.10.90.81.40.81.00.60.91.10.91.21.20.81.00.71.00.90.91.01.1
Reaction time trials completed1.73.210.01.63.21.62.00.81.92.00.81.92.01.91.91.71.91.91.01.51.71.91.61.6
Reaction time trials AUC1.63.19.91.63.11.72.00.91.91.90.81.91.91.91.81.71.91.91.01.41.61.81.61.5
Run reversals in cocaine runway, females3.03.04.21.01.90.30.90.82.01.71.91.91.92.02.02.01.71.91.81.81.91.71.92.1
Run reversals in cocaine runway, males0.30.31.9-1.0-0.6-0.7-0.4-1.4-1.1-0.30.2-0.2-0.2-0.2-0.2-0.0-0.1-0.20.20.10.10.2-0.0-0.0
Latency to leave start box in cocaine runway0.40.52.1-0.9-1.1-1.0-1.1-1.4-0.6-0.5-0.0-0.4-0.3-0.3-0.6-0.7-0.3-0.6-0.1-0.3-0.3-0.9-0.4-0.3
Latency to leave start box in cocaine runway, F0.91.04.5-1.2-1.7-2.1-2.1-1.6-0.9-0.80.4-0.5-0.5-0.4-0.7-0.9-0.5-0.70.2-0.3-0.2-0.9-0.4-0.1
Latency to leave start box in cocaine runway, M0.20.20.80.10.40.90.8-0.20.1-0.0-0.8-0.2-0.1-0.2-0.3-0.2-0.2-0.3-0.7-0.3-0.4-0.3-0.4-0.5
Std. dev. time between licks in bursts0.50.72.90.10.80.50.10.1-0.8-0.6-1.7-0.7-0.8-0.7-0.8-0.8-0.8-0.9-1.5-0.9-1.0-0.7-1.1-0.8
Total sessions with >9 infusions1.21.54.51.72.11.71.52.11.21.30.01.21.11.31.00.91.30.90.30.80.80.80.80.9
Short access day 1 total inactive lever presses0.70.94.72.21.62.11.51.50.70.8-0.60.40.40.40.40.40.30.5-0.40.0-0.1-0.20.1-0.4
Short access day 10 total inactive lever presses0.20.51.81.31.01.31.30.20.90.60.20.50.60.40.60.60.40.60.20.20.20.80.4-0.3
Short access day 1 total infusions1.41.84.61.51.81.81.42.11.71.50.41.41.61.51.11.11.51.00.61.01.00.71.10.9
Short access day 10 total infusions0.20.21.00.31.00.90.70.4-0.0-0.0-1.0-0.2-0.1-0.1-0.1-0.2-0.0-0.3-0.8-0.2-0.3-0.1-0.3-0.3
Short access total infusions0.40.62.81.11.71.20.81.40.70.6-0.60.60.90.70.40.30.60.1-0.30.30.3-0.00.20.3
Short access day 1 locomotion1.21.54.61.81.92.11.91.61.11.30.01.11.11.31.01.01.20.90.20.80.61.00.80.6
Short access day 10 total locomotion2.03.66.71.30.52.02.41.92.31.91.81.82.21.92.02.01.91.91.91.71.62.61.91.5
Short access total locomotion1.62.04.01.10.91.61.82.01.51.40.91.31.51.51.31.31.41.31.11.31.11.81.41.2
One hour access (0.3 mA shock)2.02.311.12.53.33.32.82.11.21.2-1.40.70.30.60.50.80.60.7-1.00.2-0.00.40.2-0.2
Compulsive drug intake0.10.21.00.91.00.40.1-0.6-0.30.1-0.40.1-0.4-0.00.10.1-0.10.1-0.4-0.2-0.2-0.4-0.2-0.3
One hour access (shock baseline)0.60.84.00.91.42.01.72.01.00.8-0.70.60.50.60.30.40.60.3-0.40.40.10.40.30.2
Social response proportion8.910.113.31.92.72.83.33.23.53.52.63.33.63.33.43.33.33.52.83.23.13.43.32.9
Social responses2.53.29.32.43.11.82.00.91.91.80.91.62.01.61.91.81.61.81.11.31.42.01.61.6
Social time4.35.98.41.42.41.61.82.02.72.62.22.52.62.52.72.72.52.92.32.52.62.72.62.7
Soleus weight2.05.814.03.72.23.33.02.53.32.51.62.42.42.42.42.32.42.31.71.41.32.42.01.2
Bone: stiffness0.10.11.10.50.3-0.4-0.3-1.0-0.2-0.20.10.0-0.20.0-0.1-0.10.0-0.0-0.0-0.2-0.1-0.2-0.10.0
Tibialis anterior weight0.51.63.50.0-0.10.4-0.1-0.7-0.9-1.1-1.9-1.3-1.4-1.3-1.3-1.3-1.3-1.4-1.8-1.5-1.6-1.2-1.5-1.7
Time to tail flick, vehicle, before self-admin0.80.83.41.80.91.00.71.11.30.80.60.80.90.80.90.91.00.60.60.40.40.50.70.6
Time to tail flick, vehicle, after self-admin0.10.10.30.30.60.30.20.40.20.20.10.10.60.10.10.20.20.40.10.20.20.40.20.2
Time to tail flick, test, before self-admin0.40.50.9-0.1-0.40.00.40.80.90.60.90.70.70.70.70.70.70.60.90.70.70.70.70.7
Time to tail flick, test, after self-admin0.50.50.80.30.2-0.2-0.8-0.6-0.8-0.6-0.9-0.8-0.5-0.8-0.6-0.7-0.9-0.8-0.9-0.8-0.8-0.9-0.8-0.7
Delta time to tail flick, vehicle, before/after SA0.20.20.9-0.80.4-0.4-0.3-0.5-0.9-0.4-0.7-0.5-0.1-0.5-0.5-0.4-0.6-0.3-0.6-0.2-0.2-0.2-0.4-0.2
Delta time to tail flick, test, before/after SA0.60.61.10.40.1-0.4-1.0-0.6-1.0-0.8-0.8-0.9-0.6-0.8-0.8-0.9-0.9-0.8-0.8-1.0-0.9-0.9-0.9-0.7
Tibia length0.61.84.51.90.7-0.10.2-1.71.60.92.11.21.31.21.31.31.21.41.90.71.21.41.41.0
Ambulatory time before self-admin0.50.86.7-0.9-2.6-1.1-1.5-0.3-0.3-0.70.9-0.7-0.3-0.6-0.5-0.3-0.8-0.30.6-0.3-0.3-0.7-0.1-0.6
Ambulatory time after self-admin2.32.76.01.1-0.20.91.00.92.31.62.51.71.81.71.71.81.61.92.31.61.61.51.91.2
Bone: tissue strength0.20.21.6-1.3-0.3-0.2-0.00.2-0.7-0.2-0.5-0.4-0.4-0.4-0.3-0.3-0.4-0.2-0.40.0-0.1-0.3-0.3-0.1
Total heroin consumption0.50.61.50.70.91.10.9-0.0-0.0-0.5-1.2-0.8-0.6-0.8-0.8-0.4-0.8-0.2-1.2-0.7-0.8-0.1-0.7-1.0
Bone: trabecular number0.71.13.70.51.91.71.71.51.11.2-0.41.01.01.00.90.91.00.8-0.10.90.80.80.60.5
Bone: trabecular spacing1.31.72.3-0.6-1.4-0.9-1.1-1.3-1.4-1.5-0.9-1.5-1.5-1.5-1.4-1.5-1.5-1.3-1.0-1.4-1.4-1.2-1.3-1.4
Bone: trabecular thickness1.92.410.43.12.43.22.61.72.11.4-0.31.11.01.11.01.11.11.0-0.20.20.10.90.5-0.4
Bone: trabecular tissue density0.20.22.3-0.0-1.5-0.2-0.40.5-0.1-0.50.2-0.4-0.5-0.4-0.4-0.4-0.4-0.30.0-0.4-0.5-0.3-0.3-0.6
Water consumed over 24 hours1.62.23.61.31.11.41.51.31.91.61.21.71.71.71.61.41.71.51.31.31.31.31.51.2
Number of responses in last shaping day0.20.21.1-0.01.00.30.50.60.40.5-0.00.50.40.70.50.30.60.50.10.40.50.40.40.5