Hub : Genes

Baiap2l2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc mRNA stability Baiap2l2 0.03 0.02 8.6e-04 0.02 0.02 0.01 0.02 1.7e-04 1.1e-03 2.4e-03 5.8e-04
2 PL mRNA stability Baiap2l2 0.03 0.02 6.1e-03 0.03 0.01 0.02 0.02 7.7e-04 8.9e-03 2.8e-03 2.8e-03
3 IC gene expression Baiap2l2 0.26 0.09 6.7e-11 0.28 0.24 0.25 0.28 4.6e-12 1.6e-10 6.9e-11 4.4e-12
4 PL gene expression Baiap2l2 0.2 0.07 0.0e+00 0.25 0.24 0.25 0.25 6.8e-27 5.2e-26 4.5e-27 1.0e-26
5 OFC gene expression Baiap2l2 0.28 0.13 5.4e-03 0.04 0.01 0 0.01 3.7e-02 1.9e-01 2.5e-01 2.0e-01
6 Brain gene expression Baiap2l2 0.11 0.05 2.6e-10 0.13 0.12 0.13 0.13 5.7e-12 8.0e-11 4.7e-12 4.9e-12
7 IL gene expression Baiap2l2 0.28 0.12 4.0e-04 0.11 0.04 0.07 0.07 1.4e-03 4.8e-02 8.6e-03 8.5e-03
8 NAcc isoform ratio XM_039079898.2 0.02 0.01 6.0e-03 0.01 0 0 0.01 6.1e-03 1.5e-01 2.1e-01 3.9e-02
9 NAcc gene expression Baiap2l2 0.25 0.06 0.0e+00 0.35 0.33 0.35 0.35 9.4e-56 2.3e-51 2.6e-55 2.3e-55
10 NAcc isoform ratio XR_005486728.2 0.04 0.02 5.0e-05 0.04 0.02 0.03 0.04 2.8e-06 1.6e-04 8.5e-05 2.7e-06
11 IC intron excision ratio chr7_112705433_112705746 0.08 0.04 5.9e-03 0.06 0.02 0.02 0.04 1.4e-03 3.7e-02 3.3e-02 1.1e-02
12 RMTg gene expression Baiap2l2 0.16 0.09 2.5e-03 0.01 0.06 0.02 0.04 1.8e-01 1.2e-02 1.1e-01 3.4e-02
13 Adipose gene expression Baiap2l2 0.06 0.04 1.8e-04 0.03 0.04 0.03 0.04 6.1e-04 3.5e-05 9.4e-05 7.0e-05
14 IC isoform ratio NM_001271220.1 0.1 0.06 4.1e-03 0 0.03 -0.01 -0 2.3e-01 2.1e-02 7.5e-01 3.6e-01
15 OFC intron excision ratio chr7_112705239_112705390 0.24 0.13 5.6e-03 0.03 0.01 0.02 0.05 8.5e-02 1.4e-01 9.9e-02 2.6e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Bone: apparent density0.00.00.10.10.2-0.00.10.2-0.40.30.30.3-0.2-0.10.0-0.20.40.1
Area under the delay curve1.92.25.92.42.21.81.61.51.21.61.11.1-1.00.92.0-1.0-0.90.1
BMI with tail0.31.04.0-1.5-1.5-0.4-0.9-0.9-2.0-0.6-0.4-0.50.5-0.8-1.10.31.00.2
BMI without tail0.31.03.5-1.6-1.3-0.4-0.9-0.9-1.3-0.8-0.1-0.20.2-0.2-1.90.61.6-0.9
Body weight1.46.215.1-3.4-3.9-2.7-2.6-2.4-3.1-2.7-1.7-1.81.8-1.8-3.22.01.10.0
Weight adjusted by age0.60.92.0-0.9-0.5-0.9-1.4-1.1-1.0-1.2-1.1-1.11.1-0.9-0.80.8-0.20.6
Bone surface0.10.10.40.40.20.10.10.00.40.5-0.0-0.10.1-0.10.6-0.1-0.60.5
Bone volume0.10.10.40.20.30.20.30.30.30.60.40.4-0.40.30.2-0.30.2-0.1
Breakpoint value in progressive ratio session0.20.20.70.50.40.80.60.40.00.70.40.4-0.20.00.5-0.40.10.2
Number of licking bursts0.81.22.31.11.31.41.11.01.51.31.11.1-1.21.30.4-0.70.6-1.0
Context. condit. distance diff. score3.13.811.8-3.4-2.6-2.5-2.1-1.8-1.8-2.4-1.7-1.71.7-1.5-1.80.80.80.2
Locomotion velocity, session 11.51.64.3-0.0-0.6-1.2-1.2-1.3-0.0-1.5-1.6-1.61.6-1.3-0.11.5-2.11.2
Locomotion distance, session 12.12.76.32.42.52.01.41.52.51.60.80.9-0.91.02.2-1.0-1.50.3
Locomotion velocity, session 21.01.15.20.2-0.0-0.5-0.5-0.4-0.2-0.2-1.2-1.11.1-1.21.30.2-2.02.3
Locomotion distance, session 22.33.28.93.02.21.81.91.92.31.81.11.2-1.21.02.4-0.9-1.80.6
Locomotion velocity, session 30.80.94.3-2.1-0.9-0.8-1.3-0.90.2-1.1-1.0-1.01.0-1.0-0.50.10.10.7
Locomotion distance, session 31.71.84.80.11.61.71.11.22.21.41.51.3-1.31.30.6-1.61.3-0.9
Stereotopy head waving bouts, day 31.11.32.4-0.6-1.6-1.5-1.1-1.2-1.2-1.2-1.3-1.21.1-1.0-0.81.3-0.90.8
Stereotopy head waving duration, day 34.95.98.2-1.6-2.7-2.7-2.6-2.6-2.6-2.7-2.9-2.82.7-2.4-1.52.5-1.61.8
Locomotion velocity, session 70.60.71.4-0.6-0.2-0.5-1.1-1.2-0.9-0.7-0.8-0.90.8-0.9-1.11.00.10.3
Locomotion distance, session 70.40.62.00.2-0.2-0.9-0.8-0.9-0.4-1.0-0.3-0.50.4-0.5-1.31.4-0.2-0.6
Stereotopy head waving bouts, day 73.94.47.4-2.2-1.5-2.0-2.6-2.3-1.9-2.2-2.7-2.62.6-2.5-0.81.2-0.92.2
Stereotopy head waving duration, day 73.23.86.7-2.1-1.3-1.6-2.3-2.1-2.0-2.0-2.6-2.52.5-2.4-0.40.8-0.82.3
Locomotion velocity, session 82.93.55.9-1.3-1.8-1.8-2.0-1.9-1.1-2.2-2.4-2.42.3-2.0-0.51.6-1.91.7
Locomotion distance, session 80.60.91.5-1.2-0.8-1.2-1.0-0.7-0.7-1.2-1.1-1.11.1-1.1-0.00.3-0.60.9
Degree of sensitization distance5.15.29.5-0.7-2.4-3.0-2.4-2.4-3.1-2.8-2.2-2.22.1-2.1-2.33.1-1.10.5
Degree of sensitization stereotypy3.53.87.0-1.7-0.9-1.5-2.4-2.1-1.5-1.9-2.6-2.62.6-2.5-0.10.8-1.32.5
Conditioned locomotion1.11.32.1-0.9-1.0-1.2-1.4-1.4-1.1-1.0-1.3-1.21.2-1.0-1.31.5-0.40.6
Cocaine response after cond. corrected0.80.92.40.1-0.7-0.7-0.8-0.9-1.0-0.6-1.1-1.11.1-1.00.11.0-1.61.3
Cocaine response after cond. not corrected0.40.41.40.1-0.6-0.2-0.4-0.5-0.8-0.1-0.7-0.70.8-0.70.40.5-1.21.1
Cocaine response before conditioning1.01.22.10.10.81.31.21.21.11.11.21.2-1.21.10.7-1.41.2-0.8
Saline control response0.30.42.7-1.7-1.1-0.9-0.3-0.10.1-0.4-0.1-0.10.2-0.1-0.3-0.30.5-0.2
Bone: connectivity density0.10.20.5-0.3-0.5-0.7-0.5-0.6-0.5-0.5-0.3-0.30.4-0.6-0.60.50.10.3
Bone: cortical apparent density1.01.35.1-1.00.70.50.60.71.00.61.21.2-1.31.4-0.7-1.02.3-1.7
Bone: cortical area0.30.50.90.2-1.0-0.8-0.6-0.8-0.6-0.0-0.7-0.70.7-0.9-0.30.9-0.80.9
Bone: cortical porosity0.50.61.6-0.1-1.3-0.7-0.4-0.5-0.9-0.4-0.8-0.80.9-0.80.30.4-1.11.0
Bone: cortical porosity1.92.03.9-0.3-1.9-1.4-1.1-1.3-1.3-1.0-1.6-1.71.8-1.60.11.2-2.01.7
Bone: cortical thickness0.91.43.41.10.51.01.61.31.21.81.51.5-1.41.10.8-1.00.5-0.5
Bone: cortical thickness1.41.63.01.30.91.21.71.41.41.71.41.3-1.41.51.1-0.8-0.1-0.6
Bone: cortical tissue density0.81.14.5-1.00.60.40.50.61.00.51.11.1-1.21.2-0.8-0.82.1-1.6
Condit. Reinf. active minus inactive responses0.50.61.70.10.00.10.60.51.20.61.00.8-0.81.0-0.5-0.31.0-1.3
Condit. Reinf. active-inactive response ratio0.30.31.1-0.7-0.4-0.30.1-0.01.00.10.50.3-0.30.7-0.7-0.20.9-1.1
Condit. Reinf. active responses1.41.84.40.10.60.51.11.11.30.81.81.6-1.61.6-0.6-0.92.0-2.1
Condit. Reinf. inactive responses1.62.05.30.11.10.91.21.40.70.71.91.9-1.91.4-0.5-1.12.3-2.0
Incentive salience index mean0.81.03.30.20.30.40.70.51.10.61.31.2-1.21.3-1.0-0.11.5-1.8
Condit. Reinf. lever presses1.01.34.20.20.40.80.70.50.80.61.51.5-1.41.3-1.3-0.01.9-2.0
Condit. Reinf. active minus inactive responses0.20.21.30.80.10.40.40.30.30.00.0-0.00.10.30.70.2-1.1-0.0
Condit. Reinf. active-inactive response ratio0.20.31.20.3-0.7-0.3-0.2-0.4-0.4-0.4-0.5-0.50.6-0.40.10.7-1.10.4
Condit. Reinf. active responses0.30.42.60.6-0.10.20.20.10.2-0.2-0.4-0.40.5-0.21.00.2-1.60.7
Condit. Reinf. inactive responses0.30.31.00.80.70.60.40.41.00.40.10.1-0.10.21.0-0.3-1.00.3
Condit. Reinf. lever presses0.30.40.80.60.60.70.80.70.50.40.70.7-0.70.90.4-0.30.1-0.9
Condit. Reinf. lever reinforcers received0.30.42.70.5-0.3-0.1-0.1-0.1-0.1-0.4-0.6-0.60.6-0.30.80.5-1.70.7
Conditioned reinforcement - actives1.42.54.92.01.01.62.02.02.21.91.31.3-1.31.41.9-1.2-0.8-0.2
Conditioned reinforcement - inactives2.74.06.62.51.42.02.62.42.12.32.32.3-2.32.21.2-1.20.2-1.4
Conditioned locomotion0.81.02.81.4-0.00.81.31.50.81.10.40.3-0.30.31.7-0.6-1.40.9
Patch foraging indifference point 0 sec0.20.41.8-0.5-1.1-0.4-0.4-0.5-0.0-0.30.20.3-0.2-0.1-1.40.80.6-0.6
Patch foraging indifference point AUC1.11.54.92.01.31.31.21.02.21.21.11.1-1.01.40.6-0.2-0.5-0.8
Delay disc. indifference point, 0s delay0.10.10.4-0.2-0.40.10.40.2-0.60.30.20.3-0.1-0.20.3-0.20.00.3
Delay disc. indifference point, 16s delay2.02.27.42.72.21.51.61.51.21.51.01.0-1.00.92.0-0.9-1.00.1
Delay disc. indifference point, 2s delay4.55.014.42.82.62.82.52.61.62.71.41.4-1.40.93.8-2.3-1.31.1
Delay disc. indifference point, 24s delay0.30.31.11.10.70.0-0.4-0.60.90.0-0.3-0.20.20.0-0.41.0-0.9-0.0
Delay disc. indifference point, 4s delay0.80.92.91.51.41.20.90.80.30.70.20.2-0.10.21.7-0.6-1.10.6
Delay disc. indifference point, 8s delay1.61.93.71.91.81.61.61.21.41.41.61.6-1.51.40.8-0.70.2-1.1
Indifference point function ln k1.22.15.8-2.4-1.7-1.7-1.6-1.4-1.9-1.5-1.4-1.41.3-1.5-0.90.40.40.9
Indifference point function log k1.22.15.8-2.4-1.7-1.7-1.6-1.4-1.9-1.5-1.4-1.41.3-1.5-0.90.40.40.9
Patch foraging total patch changes 0 sec0.20.30.8-0.2-0.70.10.20.10.40.20.70.8-0.70.4-0.90.20.8-0.9
Patch foraging total patch changes 12 sec0.10.20.70.4-0.60.20.2-0.10.90.20.20.2-0.0-0.0-0.00.5-0.80.3
Patch foraging total patch changes 18 sec0.30.41.51.2-0.30.50.50.21.00.60.60.7-0.50.5-0.50.7-0.5-0.5
Patch foraging total patch changes 24 sec0.91.63.91.00.61.21.21.02.01.21.71.6-1.51.4-0.3-0.40.9-1.6
Patch foraging total patch changes 6 sec0.30.41.51.20.00.50.60.40.90.60.80.8-0.70.6-0.30.4-0.3-0.5
Patch foraging time to switch 0 sec0.50.92.80.4-0.3-0.3-0.4-0.4-1.7-0.5-1.1-1.00.9-1.31.00.3-1.41.7
Patch foraging water rate 0 sec0.51.15.6-0.9-0.8-0.5-0.6-0.70.3-0.50.40.4-0.30.7-2.41.11.5-1.8
Patch foraging water rate 12 sec0.30.62.5-0.80.00.20.10.00.60.50.60.7-0.70.8-1.0-0.21.6-1.3
Patch foraging water rate 18 sec0.40.63.7-0.6-0.4-0.7-0.8-1.00.6-0.5-0.1-0.1-0.00.2-1.91.10.7-1.0
Patch foraging water rate 24 sec1.62.24.7-2.2-1.9-1.8-1.7-1.8-1.0-1.7-1.3-1.21.1-0.9-2.11.40.6-0.3
Patch foraging water rate 6 sec1.11.66.0-1.00.00.20.50.41.00.61.31.4-1.41.4-1.6-0.42.4-2.1
Seeking ratio, delayed vs. immediate footshock0.10.20.70.40.80.7-0.10.20.10.4-0.2-0.00.1-0.20.5-0.2-0.30.5
Distance traveled before self-admin0.50.62.71.61.00.30.60.6-0.20.50.10.1-0.0-0.11.4-0.1-1.40.8
Distance traveled after self-admin0.40.52.50.6-0.6-0.8-0.6-0.9-0.3-0.7-0.4-0.40.3-0.2-1.11.6-0.8-0.2
Extensor digitorum longus weight0.62.44.21.01.91.81.81.90.22.01.51.5-1.61.41.9-2.00.8-0.5
Bone: elastic displacement1.21.42.1-0.7-0.8-1.1-1.5-1.3-1.3-1.4-1.4-1.41.3-1.2-0.81.2-0.60.7
Bone: elastic work3.95.17.9-0.6-2.0-2.2-2.3-2.4-2.5-2.0-2.5-2.62.7-2.8-0.92.4-2.12.4
Bone: endosteal estimation2.04.36.8-0.7-1.9-1.9-2.3-2.2-1.7-2.0-2.6-2.62.5-2.2-0.82.3-2.31.9
Bone: endosteal perimeter2.14.47.1-0.7-1.9-1.9-2.4-2.5-1.9-1.7-2.7-2.62.5-2.4-0.82.1-2.02.2
Epididymis fat weight1.34.513.1-3.4-3.6-2.6-2.0-1.9-2.4-2.3-1.7-1.71.6-1.9-1.91.10.60.6
Delta time in closed arm before/after self-admin1.01.02.10.80.20.91.41.31.11.21.11.1-1.01.10.9-0.9-0.0-0.4
Delta time in open arm before/after self-admin0.30.20.50.20.2-0.3-0.5-0.4-0.4-0.7-0.5-0.50.6-0.70.10.4-0.60.6
Diff in mean of infusions in LGA sessions0.20.20.6-0.1-0.3-0.4-0.5-0.70.0-0.5-0.3-0.40.5-0.3-0.70.8-0.3-0.1
Delay discount exponential model param1.92.25.8-2.4-2.2-1.9-1.6-1.4-1.3-1.6-1.1-1.11.0-0.9-1.91.00.9-0.1
Extinction: sum of active levers before priming0.70.82.41.41.00.90.50.20.30.7-0.2-0.30.4-0.51.6-0.3-1.51.5
Active lever presses in extinction session 60.20.20.70.10.1-0.1-0.2-0.4-0.10.1-0.5-0.50.5-0.50.40.1-0.60.8
Bone: final force0.91.53.20.2-1.2-0.9-1.0-1.3-1.1-0.5-1.3-1.31.4-1.5-0.21.5-1.81.8
Bone: final moment1.21.93.50.1-1.4-1.1-1.2-1.5-1.2-0.7-1.5-1.51.6-1.7-0.41.7-1.91.8
Food consumed during 24 hour testing period0.10.20.70.0-0.80.00.20.00.20.3-0.1-0.20.2-0.40.40.1-0.80.8
Glucose0.40.62.0-0.1-1.0-0.20.60.3-0.20.20.90.9-0.90.8-1.10.11.3-1.4
Heart weight4.56.910.8-1.8-2.8-2.9-3.1-3.3-2.6-2.8-2.8-2.92.9-2.6-2.32.9-1.31.5
Delay discount hyperbolic model param2.42.76.0-2.5-2.3-2.1-1.8-1.7-1.4-1.7-1.2-1.31.1-1.0-2.31.30.8-0.1
Intermittent access intake day 1-15 change0.20.40.9-0.20.00.60.70.80.80.80.80.8-0.70.60.3-0.90.7-0.4
Intermittent access intake escalation0.20.50.9-0.10.30.60.70.80.90.70.90.8-0.80.70.3-0.90.8-0.5
Intermittent access intake escalation 20.50.51.4-0.30.30.30.60.60.70.60.90.9-1.00.9-0.2-0.71.2-1.0
Intermitt. access day 1 inactive lever presses0.31.03.60.3-1.0-1.3-0.9-1.2-1.0-1.2-0.6-0.60.6-0.7-1.51.9-0.6-0.2
Intermitt. access day 15 inactive lever presses0.10.20.80.9-0.0-0.30.10.00.1-0.10.40.5-0.40.3-0.50.7-0.2-0.6
Intermitt. access escalation Index1.31.83.60.31.41.91.51.31.41.61.41.4-1.31.31.0-1.71.0-0.8
Intermittent access day 1 total infusions1.11.76.22.50.51.01.31.41.61.20.20.1-0.20.42.1-0.3-2.30.9
Intermittent access day 15 total infusions1.21.73.82.01.01.41.61.61.81.60.90.8-0.80.81.9-1.0-1.10.3
Intermittent access terminal intake (last 3 days)1.01.34.02.01.01.11.21.31.71.20.50.4-0.50.51.8-0.6-1.40.5
Intermittent access total infusions1.92.38.32.90.91.41.71.71.71.60.60.5-0.50.62.3-0.5-2.20.8
Intermittent access day 1 locomotion0.70.93.81.90.61.01.21.11.01.10.70.5-0.60.71.1-0.2-1.0-0.0
Intermittent access day 15 total locomotion0.20.51.21.1-0.10.41.00.90.80.80.60.4-0.70.70.6-0.2-0.6-0.2
Intermittent access total locomotion0.40.51.11.1-0.60.31.00.80.60.80.80.6-0.80.80.10.2-0.4-0.5
Intermittent access standard deviation0.20.51.81.2-1.2-0.80.20.0-0.40.0-0.1-0.10.3-0.6-0.11.0-1.30.5
Left kidney weight6.128.342.6-4.2-6.5-6.2-5.7-5.6-4.9-5.6-5.9-6.16.1-5.9-2.84.7-3.64.4
Right kidney weight7.132.558.7-5.1-7.7-6.8-5.9-6.0-5.8-6.3-5.9-6.06.0-6.2-4.05.2-2.83.9
Cocaine induced anxiety0.20.30.8-0.8-0.8-0.9-0.5-0.2-0.8-0.3-0.5-0.50.5-0.9-0.10.00.00.7
Post-drug Anxiety0.70.82.1-1.4-0.8-1.0-1.0-0.8-1.4-0.8-0.4-0.50.4-0.7-1.20.41.2-0.2
Baseline Anxiety0.20.30.90.20.70.70.3-0.00.20.30.50.5-0.50.8-0.3-0.10.7-1.0
Tail length0.41.55.5-1.8-1.4-1.3-0.8-0.6-0.4-1.10.20.1-0.20.4-2.30.71.9-1.8
Length with tail1.25.211.5-3.3-3.4-3.2-2.4-2.3-1.9-2.7-1.6-1.71.6-1.4-3.11.90.9-0.4
Length without tail2.58.116.5-2.6-4.1-3.6-3.0-3.1-2.7-3.1-2.9-2.92.9-2.8-2.32.7-1.11.5
Times rat made contact with spout2.32.66.40.20.41.01.31.02.51.52.01.9-1.82.2-0.9-0.61.8-2.5
Lifetime Intake1.92.49.33.00.71.31.71.61.61.60.50.4-0.40.52.3-0.4-2.40.9
Liver weight, left0.10.21.5-1.2-0.7-0.3-0.10.10.3-0.3-0.2-0.20.10.20.1-0.60.4-0.0
Liver weight, right1.32.313.3-3.6-2.2-1.4-1.4-1.2-0.5-1.5-0.9-1.00.9-0.6-1.6-0.01.6-0.4
Locomotor activity0.81.35.0-2.0-2.2-1.2-0.9-0.9-0.9-1.0-1.0-1.00.9-1.1-0.70.5-0.10.7
Locomotor testing distance0.40.81.4-0.7-0.50.50.90.70.91.01.11.1-1.11.0-0.1-0.81.2-0.9
Locomotor testing rearing0.20.42.1-1.2-1.4-0.7-0.2-0.40.2-0.1-0.6-0.50.4-0.40.00.0-0.30.6
Locomotion in novel chamber2.02.54.2-0.11.81.51.61.71.31.41.81.7-1.71.90.7-2.02.0-1.4
Locomotion in novel chamber post-restriction1.93.14.71.01.92.22.02.01.92.11.71.5-1.72.01.7-2.10.8-0.9
Fecal boli incidents, locomotor time 10.30.42.21.1-0.3-0.2-0.2-0.50.6-0.3-0.3-0.30.40.4-0.91.5-1.0-0.4
Change in fecal boli incidents, locomotor task0.40.42.4-1.5-0.8-0.6-0.8-0.70.1-0.4-0.5-0.30.4-0.4-0.70.10.50.0
Time >=10cm from walls, locomotor time 11.01.11.7-0.3-1.3-1.2-1.0-0.8-1.1-1.0-1.1-1.21.2-1.1-0.61.2-1.01.0
Bouts of movement, locomotor time 10.10.10.5-0.5-0.7-0.2-0.2-0.10.1-0.0-0.1-0.20.1-0.1-0.40.20.2-0.1
Total resting periods, locomotor time 10.10.10.4-0.1-0.6-0.3-0.4-0.3-0.4-0.2-0.3-0.40.3-0.3-0.50.6-0.20.1
Rest time, locomotor task time 10.40.51.70.2-0.7-0.7-0.8-0.7-0.8-0.8-0.5-0.40.4-0.4-1.21.3-0.2-0.1
Distance moved, locomotor task time 10.20.22.0-1.4-0.3-0.4-0.4-0.2-0.1-0.4-0.5-0.60.4-0.20.2-0.40.20.3
Vertical activity count, locomotor time 10.40.93.4-1.6-1.1-0.5-0.1-0.3-0.1-0.40.60.6-0.70.6-1.60.11.8-1.4
Time >=10cm from walls, locomotor time 20.91.44.0-0.4-0.9-0.9-1.5-1.8-0.9-0.9-1.0-1.00.9-0.8-2.01.9-0.10.2
Bouts of movement, locomotor time 21.42.24.40.61.11.91.82.01.12.01.31.3-1.21.32.0-2.10.4-0.2
Total resting periods, locomotor time 21.42.45.31.01.32.11.92.11.12.11.21.2-1.21.22.3-2.00.00.0
Rest time, locomotor task time 20.10.10.70.90.30.30.20.20.10.10.20.1-0.20.10.00.3-0.40.0
Distance moved, locomotor task time 20.70.92.0-1.4-0.8-1.0-1.2-1.3-0.8-0.9-0.9-1.00.9-0.8-1.10.70.30.2
Vertical activity count, locomotor time 20.60.83.6-1.4-1.2-0.6-0.7-1.0-0.5-0.6-0.0-0.10.1-0.0-1.90.91.2-0.8
Light reinforcement 10.00.10.40.2-0.00.2-0.1-0.30.00.1-0.3-0.20.3-0.40.30.1-0.50.6
Light reinforcement 20.20.21.3-0.7-0.3-0.1-0.2-0.1-0.40.1-0.4-0.40.4-0.50.6-0.5-0.21.1
Bone: marrow area2.14.67.3-0.7-2.0-2.0-2.3-2.3-1.7-2.1-2.7-2.72.6-2.3-0.92.4-2.42.0
Bone: maximum diameter2.54.66.7-0.7-2.5-2.3-2.3-2.3-1.9-1.8-2.6-2.62.5-2.4-1.02.3-2.12.1
Bone: maximum force1.01.84.30.4-1.5-1.1-1.0-1.4-1.1-0.5-1.4-1.41.5-1.6-0.21.7-2.11.9
Bone: maximum moment1.32.34.90.3-1.6-1.3-1.2-1.6-1.3-0.8-1.6-1.61.7-1.8-0.31.9-2.22.0
Mean time between licks in bursts0.30.62.00.71.30.7-0.2-0.1-0.90.1-0.6-0.60.6-0.41.4-0.3-1.11.2
Mean num. licks in bursts0.20.31.3-1.1-1.1-0.7-0.1-0.20.4-0.30.20.2-0.10.1-0.90.10.7-0.7
Cd content in liver0.30.30.9-1.0-0.50.20.30.30.90.60.30.2-0.2-0.00.6-0.90.20.6
Co content in liver0.60.71.70.80.60.91.10.71.11.31.00.9-0.91.10.5-0.50.2-0.5
Cu content in liver3.44.17.31.92.72.42.01.91.82.22.12.2-2.22.60.8-1.41.2-1.8
Fe content in liver5.46.68.3-1.8-2.9-2.9-2.8-2.8-2.8-2.7-2.8-2.92.9-2.9-1.62.4-1.52.1
K content in liver0.10.10.40.60.6-0.00.20.10.20.20.30.3-0.20.6-0.10.00.2-0.6
Mg content in liver0.10.10.50.70.4-0.10.10.10.30.20.20.2-0.20.5-0.20.30.0-0.5
Mn content in liver0.60.71.10.40.90.80.90.91.00.90.80.9-0.81.00.8-1.00.4-0.5
Na content in liver0.10.10.60.20.1-0.3-0.1-0.2-0.3-0.10.20.2-0.10.3-0.80.40.6-0.7
Rb content in liver0.10.10.90.90.20.1-0.2-0.2-0.10.1-0.2-0.10.00.1-0.10.7-0.8-0.1
Se content in liver0.70.82.5-0.50.70.80.90.81.11.10.80.7-0.60.80.8-1.61.0-0.2
Sr content in liver5.74.97.31.22.72.52.42.31.72.32.72.7-2.42.31.0-2.22.1-2.0
Zn content in liver0.40.41.5-0.20.20.20.60.51.20.40.60.6-0.61.10.1-0.60.6-0.9
Bone: minimum diameter0.30.51.30.3-1.0-0.8-0.5-0.6-0.4-0.4-0.7-0.70.8-0.80.00.7-1.21.0
Time in familiar zone, hab. session 10.40.41.00.70.30.1-0.7-0.8-0.2-0.2-0.6-0.80.7-0.7-0.31.0-0.90.7
Time in novel zone, hab. session 10.40.42.3-1.5-1.3-0.8-0.5-0.3-0.7-0.5-0.5-0.40.4-0.4-0.1-0.20.20.3
Total zone transitions, hab. session 12.02.74.50.82.01.61.71.92.11.71.81.7-1.71.61.5-2.11.0-0.8
Total locomotion distance, hab. session 11.01.43.3-0.21.00.71.11.31.81.21.41.2-1.21.40.7-1.71.2-1.0
Locomotion velocity, hab. session 11.21.73.40.31.30.81.31.41.81.31.51.4-1.51.50.8-1.61.1-1.1
Time in familiar zone, hab. session 20.20.30.8-0.30.90.80.20.20.60.50.40.4-0.30.30.0-0.60.9-0.2
Time in novel zone, hab. session 20.10.10.60.3-0.8-0.40.60.50.10.10.30.3-0.40.30.3-0.1-0.4-0.3
Total zone transitions, hab. session 20.50.72.51.50.90.50.70.71.60.40.60.7-0.71.10.20.1-0.5-0.7
Total locomotion distance, hab. session 20.30.42.01.40.50.20.50.41.00.40.20.1-0.10.50.60.2-1.10.1
Locomotion velocity, hab. session 20.30.42.61.60.70.30.50.41.00.40.30.2-0.20.60.40.4-1.0-0.2
Novel to familiar place preference ratio1.11.25.2-2.3-1.6-1.5-1.0-0.9-0.5-1.0-0.9-1.11.1-1.0-0.4-0.00.20.6
Novelty place preference1.21.36.6-2.6-1.7-1.6-1.0-0.9-0.4-0.9-0.8-1.01.0-0.9-0.5-0.20.50.5
Time in novel zone, NPP test1.31.47.6-2.8-1.8-1.6-1.0-0.9-0.4-1.0-0.8-1.01.0-0.9-0.6-0.20.60.5
Total zone transitions, NPP test1.52.15.51.32.01.21.51.62.31.41.51.5-1.51.51.1-1.30.3-0.7
Total locomotion distance, NPP test0.20.31.10.80.90.20.20.21.00.30.10.1-0.10.30.50.0-0.80.1
Locomotion velocity, NPP test0.40.62.11.21.50.70.60.61.30.70.50.5-0.40.60.8-0.3-0.6-0.1
Intraocular pressure0.50.71.1-0.6-1.0-0.8-0.9-0.8-0.3-0.8-1.0-1.01.1-1.10.00.5-0.91.0
Delta distance traveled before/after self-admin1.81.96.5-1.5-1.9-1.7-1.5-1.7-0.2-1.5-0.8-0.90.6-0.6-2.61.70.4-0.6
Delta ambulatory time before/after self-admin1.62.05.2-1.2-1.8-1.7-1.6-2.0-0.1-1.6-1.2-1.21.0-0.9-2.31.9-0.2-0.2
Parametrial fat weight0.61.46.5-2.1-0.7-0.3-0.5-0.7-0.7-0.40.40.4-0.50.5-2.10.12.5-1.6
Pavlov. Cond. lever latency0.10.10.7-0.4-0.4-0.8-0.3-0.2-0.3-0.5-0.5-0.40.4-0.10.10.1-0.30.2
Pavlov. Cond. magazine entry latency0.81.03.92.01.41.70.90.80.51.20.60.6-0.60.31.1-0.4-0.60.3
Pavlov. Cond. change in total contacts1.61.75.82.41.61.81.41.21.51.61.11.0-1.00.91.3-0.6-0.7-0.0
Pavlov. Cond. index score0.30.41.81.40.71.20.50.40.50.80.40.4-0.40.10.20.1-0.40.1
Pavlov. Cond. latency score0.20.21.11.00.51.00.40.30.30.60.40.3-0.30.00.10.1-0.10.1
Pavlov. Cond. lever contacts0.50.51.81.20.91.30.60.50.50.90.90.8-0.80.5-0.1-0.10.4-0.5
Pavlov. Cond. magazine entry number1.01.34.3-2.1-1.5-1.7-1.1-1.0-1.1-1.3-1.0-0.90.9-0.7-0.90.40.40.2
Pavlov. Cond. intertrial magazine entries0.40.52.2-0.10.1-0.20.30.10.50.00.80.7-0.70.8-1.00.11.1-1.5
Pavlov. Cond. lever-magazine prob. diff.0.40.51.91.40.91.30.60.50.70.90.60.6-0.50.30.4-0.1-0.2-0.0
Pavlov. Cond. response bias0.70.93.41.81.31.50.80.70.71.10.90.8-0.80.50.5-0.1-0.2-0.2
Pavlov. Cond. lever latency0.20.30.90.00.30.40.60.70.90.70.40.4-0.40.30.9-1.00.00.5
Pavlov. Cond. magazine entry latency0.70.82.11.50.90.71.10.90.50.71.11.0-1.01.00.2-0.10.1-1.2
Pavlov. Cond. change in total contacts2.43.89.1-0.2-1.7-1.9-2.1-2.3-2.5-2.2-1.9-2.02.0-1.8-2.03.0-1.50.5
Pavlov. Cond. index score0.20.21.00.5-0.1-0.3-0.2-0.3-0.5-0.40.0-0.00.10.1-0.81.0-0.1-0.9
Pavlov. Cond. latency score0.20.31.10.70.1-0.3-0.1-0.3-0.4-0.40.20.1-0.10.2-0.91.10.0-1.1
Pavlov. Cond. lever contacts0.20.30.9-0.2-0.4-0.4-0.5-0.6-0.7-0.7-0.3-0.30.3-0.2-1.00.90.2-0.6
Pavlov. Cond. magazine entry number0.10.20.8-0.5-0.10.30.00.20.30.4-0.1-0.10.0-0.20.6-0.7-0.00.9
Pavlov. Cond. intertrial magazine entries0.10.10.30.3-0.3-0.2-0.0-0.10.3-0.10.10.1-0.20.3-0.60.5-0.0-0.5
Pavlov. Cond. lever-magazine prob. diff.0.10.20.80.5-0.0-0.3-0.2-0.3-0.6-0.40.0-0.10.10.0-0.70.9-0.1-0.7
Pavlov. Cond. response bias0.20.21.00.5-0.0-0.3-0.3-0.5-0.7-0.5-0.3-0.30.3-0.2-0.61.0-0.4-0.3
Time in closed arm before self-admin0.30.40.90.80.60.00.50.5-0.30.50.90.9-0.90.6-0.2-0.20.8-0.8
Time in closed arm after self-admin0.60.61.90.0-0.5-0.10.60.40.30.31.01.0-1.11.1-0.8-0.01.0-1.4
Time in open arm before self-admin0.10.10.4-0.40.2-0.0-0.3-0.30.2-0.3-0.1-0.1-0.10.1-0.60.20.5-0.4
Time in open arm after self-admin0.10.10.4-0.20.70.5-0.1-0.10.10.00.10.1-0.0-0.10.2-0.30.30.0
Bone: periosteal estimation1.53.24.7-0.3-1.8-1.7-1.9-1.9-1.5-1.4-2.2-2.22.1-2.0-0.62.0-2.11.9
Bone: periosteal perimeter3.05.27.3-1.0-2.6-2.4-2.5-2.7-1.8-1.8-2.7-2.72.6-2.6-1.22.4-2.02.3
Bone: post-yield work0.30.42.01.10.10.2-0.0-0.30.40.3-0.3-0.40.4-0.40.50.6-1.40.9
Progressive ratio test 1 active lever presses1.21.56.12.50.61.11.21.21.21.10.20.2-0.20.41.9-0.3-2.10.8
Progressive ratio test 1 breakpoint1.11.45.72.40.71.11.11.21.31.00.20.2-0.20.41.8-0.2-2.00.8
Progressive ratio test 1 inactive lever presses0.91.37.42.70.90.91.11.4-0.00.90.30.3-0.30.31.60.1-1.80.6
Progressive ratio test 2 active lever presses2.22.55.92.40.91.62.12.02.11.91.41.3-1.31.41.8-0.9-1.0-0.3
Progressive ratio test 2 breakpoint2.32.76.62.61.11.72.12.02.11.91.31.2-1.31.32.0-1.0-1.2-0.1
Progressive ratio test 2 inactive lever presses2.54.06.52.61.82.12.42.32.42.32.12.1-2.11.91.6-1.4-0.0-1.1
Incentive Sensitization - Responses1.01.42.31.00.81.21.51.31.51.41.41.2-1.31.30.8-1.00.4-0.8
Incentive Sensitization - Breakpoint1.01.32.21.00.71.21.51.41.51.31.31.2-1.31.20.8-1.00.3-0.7
Sum of active levers in priming session hrs 5-60.10.10.4-0.30.0-0.2-0.1-0.2-0.6-0.1-0.1-0.10.3-0.0-0.10.10.20.1
Progressive ratio0.10.20.50.2-0.5-0.2-0.3-0.2-0.4-0.4-0.4-0.30.4-0.70.10.4-0.70.6
Food seeking constrained by brief footshock0.20.31.00.2-0.10.50.50.20.70.9-0.1-0.10.1-0.01.0-0.4-0.80.8
Seeking ratio, punishment vs. effort0.10.10.50.30.30.40.30.00.50.70.10.1-0.10.40.2-0.1-0.10.1
Retroperitoneal fat weight1.98.217.3-4.0-4.2-3.0-2.9-3.3-3.5-2.6-2.6-2.72.8-3.0-2.31.90.21.7
Reaction time number correct0.61.13.00.31.41.30.80.91.71.20.90.9-0.80.90.9-1.40.7-0.3
Reaction time mean minus median0.00.10.3-0.0-0.0-0.5-0.3-0.3-0.4-0.4-0.3-0.40.3-0.3-0.10.2-0.30.3
Reaction time mean minus median AUC0.10.20.6-0.7-0.6-0.8-0.4-0.3-0.7-0.6-0.3-0.40.3-0.4-0.40.20.20.1
Reaction time num false alarms0.10.20.5-0.6-0.7-0.40.30.20.40.40.40.4-0.10.30.0-0.50.6-0.2
Reaction time num false alarms AUC0.10.20.5-0.6-0.6-0.30.40.30.60.40.40.4-0.20.40.2-0.70.6-0.2
Reaction time trials correct on left0.61.13.00.31.41.30.80.91.71.20.90.9-0.80.90.9-1.40.7-0.3
Reaction time trials on left0.71.33.40.41.51.41.01.01.91.31.01.0-0.91.01.0-1.50.7-0.3
Reaction time mean0.40.62.0-0.3-0.2-1.2-0.9-0.8-1.4-1.0-0.7-0.70.5-0.6-0.70.8-0.1-0.0
Reaction time mean AUC0.20.31.0-0.30.0-1.0-0.6-0.6-1.0-0.8-0.5-0.60.4-0.4-0.50.6-0.0-0.1
Median of all reaction times0.40.62.3-0.2-0.0-1.1-0.9-0.8-1.5-1.0-0.8-0.80.6-0.6-0.60.9-0.1-0.0
Reaction time omissions1.42.06.21.71.71.61.61.60.91.70.90.8-0.90.62.5-1.7-0.70.9
Reaction time false alarm rate0.10.21.2-0.7-1.1-0.80.1-0.0-0.4-0.10.10.10.00.0-0.2-0.20.4-0.1
Reaction time premature initiation rate0.30.41.00.7-1.0-0.3-0.3-0.5-0.4-0.3-0.5-0.50.5-0.8-0.31.0-0.90.6
Reaction time premature initiations0.00.10.40.6-0.40.20.10.00.40.10.00.00.0-0.2-0.00.3-0.40.3
Std. dev. reaction times0.20.41.0-0.6-0.7-1.0-0.6-0.6-0.8-0.8-0.5-0.60.5-0.7-0.60.50.10.2
Reaction time trials completed0.71.33.40.41.51.41.01.01.91.31.01.0-0.91.01.0-1.50.7-0.3
Reaction time trials AUC0.50.92.70.11.21.20.80.91.71.10.80.8-0.70.70.9-1.40.6-0.1
Run reversals in cocaine runway, females0.40.41.0-1.0-0.1-0.7-0.8-0.7-0.6-0.4-0.10.00.2-0.4-1.00.30.9-0.2
Run reversals in cocaine runway, males0.60.61.6-0.2-0.6-1.2-0.7-0.40.6-1.2-0.9-0.91.0-0.30.00.6-1.30.4
Latency to leave start box in cocaine runway1.31.43.3-0.3-0.2-0.5-1.2-0.9-1.6-1.0-1.8-1.61.6-1.50.60.4-1.31.6
Latency to leave start box in cocaine runway, F1.11.33.10.40.3-0.0-1.1-0.9-1.4-0.8-1.8-1.41.4-1.30.60.8-1.61.5
Latency to leave start box in cocaine runway, M0.40.41.2-1.1-0.8-0.8-0.4-0.3-0.8-0.6-0.6-0.60.7-0.60.2-0.30.00.5
Std. dev. time between licks in bursts0.30.41.00.50.1-0.3-0.7-0.7-0.5-0.9-0.7-0.80.7-0.4-0.41.0-0.80.0
Total sessions with >9 infusions1.01.27.01.6-0.6-0.00.10.10.2-0.0-0.9-0.90.9-0.81.10.8-2.61.5
Short access day 1 total inactive lever presses1.82.46.71.0-1.4-1.8-1.3-1.2-1.3-1.7-1.5-1.51.4-1.3-1.02.6-2.30.8
Short access day 10 total inactive lever presses0.82.08.1-1.0-1.4-1.9-1.5-1.8-0.8-1.7-0.4-0.30.2-0.4-2.82.00.8-1.3
Short access day 1 total infusions0.40.52.41.3-0.6-0.5-0.3-0.5-0.1-0.5-0.5-0.50.5-0.4-0.21.3-1.50.3
Short access day 10 total infusions0.81.05.91.5-0.40.10.20.30.50.1-0.7-0.70.7-0.71.30.4-2.41.5
Short access total infusions1.01.37.22.4-0.10.30.60.50.60.4-0.5-0.50.5-0.31.50.5-2.71.3
Short access day 1 locomotion0.30.31.20.7-0.8-0.5-0.3-0.1-0.1-0.6-0.4-0.50.4-0.2-0.41.1-1.10.1
Short access day 10 total locomotion0.40.72.31.2-0.30.20.80.5-0.00.41.21.0-1.11.0-0.90.70.5-1.5
Short access total locomotion0.20.21.11.0-0.70.10.40.4-0.10.10.20.1-0.10.10.00.6-0.8-0.0
One hour access (0.3 mA shock)5.86.711.03.32.43.13.13.23.33.02.22.1-2.32.33.0-2.2-0.8-0.5
Compulsive drug intake1.01.22.40.81.21.00.90.91.20.81.41.3-1.51.4-0.2-0.61.1-1.5
One hour access (shock baseline)1.11.75.21.81.01.51.61.81.31.50.60.5-0.60.72.3-1.2-1.20.7
Social response proportion2.12.39.00.5-0.2-0.4-0.9-0.6-2.2-0.6-1.7-1.71.7-2.31.30.3-2.03.0
Social responses0.30.41.70.90.30.60.30.30.00.3-0.1-0.20.2-0.61.2-0.2-1.21.3
Social time1.31.84.42.11.51.81.61.41.11.71.21.2-1.11.11.3-0.7-0.4-0.3
Soleus weight0.82.47.60.80.30.81.41.01.21.22.02.0-2.02.0-1.40.11.9-2.8
Bone: stiffness1.01.63.1-0.1-1.6-1.2-1.1-1.4-1.5-0.7-1.2-1.21.3-1.4-0.91.7-1.21.4
Tibialis anterior weight2.68.713.12.63.03.23.63.62.13.53.33.3-3.33.12.6-3.01.3-1.6
Time to tail flick, vehicle, before self-admin0.10.10.40.00.1-0.20.40.60.00.10.10.2-0.30.10.5-0.5-0.00.3
Time to tail flick, vehicle, after self-admin0.50.63.0-1.0-0.6-0.8-0.6-0.6-0.2-0.80.00.0-0.10.5-1.70.71.0-1.1
Time to tail flick, test, before self-admin1.31.32.60.60.81.41.41.51.31.31.21.1-1.11.01.4-1.60.4-0.3
Time to tail flick, test, after self-admin0.20.21.00.00.60.30.0-0.00.20.30.40.4-0.60.7-0.60.00.7-1.0
Delta time to tail flick, vehicle, before/after SA0.60.61.50.0-0.6-0.6-0.8-1.0-0.5-0.9-0.8-0.90.9-0.6-0.81.2-0.70.2
Delta time to tail flick, test, before/after SA0.60.62.2-0.30.60.40.20.1-0.10.40.80.9-0.90.9-0.8-0.21.5-1.4
Tibia length0.51.32.2-0.3-1.2-1.1-1.2-1.3-1.1-0.7-1.3-1.21.3-1.5-0.61.3-1.21.3
Ambulatory time before self-admin0.40.71.81.31.10.71.01.00.20.80.70.7-0.70.61.2-0.5-0.50.0
Ambulatory time after self-admin0.20.21.00.4-0.1-0.4-0.2-0.70.3-0.30.00.1-0.20.2-1.01.0-0.2-0.5
Bone: tissue strength0.40.40.8-0.4-0.8-0.8-0.6-0.7-0.9-0.5-0.5-0.50.6-0.8-0.50.4-0.00.6
Total heroin consumption0.80.92.61.00.61.01.20.91.31.30.60.6-0.40.21.6-0.9-0.90.8
Bone: trabecular number0.10.10.3-0.50.1-0.2-0.4-0.4-0.3-0.2-0.1-0.10.2-0.4-0.3-0.10.50.2
Bone: trabecular spacing0.40.62.30.2-0.9-0.7-0.6-0.8-0.5-0.4-0.8-0.80.7-0.3-0.81.5-1.10.2
Bone: trabecular thickness0.20.31.3-0.00.50.30.30.40.00.20.60.6-0.60.2-0.2-0.61.2-0.5
Bone: trabecular tissue density0.30.52.5-0.40.30.40.10.3-0.30.00.60.7-0.80.6-0.9-0.21.6-1.2
Water consumed over 24 hours0.60.82.30.0-0.20.40.80.51.50.71.21.1-1.01.0-0.6-0.20.9-1.4
Number of responses in last shaping day1.92.18.83.01.11.41.61.70.91.60.60.5-0.50.52.2-0.5-1.90.7