Baiap2l2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL mRNA stability Baiap2l2 0.03 0.02 9.1e-03 0.01 0.02 0.02 0.01 9.5e-03 6.2e-03 3.4e-03 8.3e-03
2 PL gene expression Baiap2l2 0.22 0.07 0.0e+00 0.24 0.22 0.25 0.24 4.4e-26 2.3e-24 2.3e-27 3.7e-26
3 Brain gene expression Baiap2l2 0.11 0.05 1.1e-09 0.11 0.08 0.08 0.1 4.7e-10 4.0e-08 3.0e-08 3.0e-09
4 IL gene expression Baiap2l2 0.3 0.14 3.3e-04 0.1 0.03 0.05 0.05 2.3e-03 5.6e-02 2.6e-02 2.0e-02
5 NAcc gene expression Baiap2l2 0.24 0.07 0.0e+00 0.31 0.3 0.32 0.31 3.9e-36 1.1e-35 3.2e-37 1.0e-36
6 NAcc mRNA stability Baiap2l2 0.05 0.03 2.9e-03 0 0.01 0.01 0 1.8e-01 4.3e-02 4.6e-02 1.5e-01
7 OFC gene expression Baiap2l2 0.37 0.15 4.6e-04 0.06 0.04 0.08 0.06 1.7e-02 4.0e-02 7.0e-03 1.5e-02
8 Eye isoform ratio XM_039079898.1 0.59 0.16 1.1e-03 0.01 0.02 -0.01 0.03 2.1e-01 1.7e-01 4.2e-01 1.0e-01
9 RMTg gene expression Baiap2l2 0.14 0.08 3.1e-03 0.05 0.05 0.04 0.04 2.1e-02 1.5e-02 3.0e-02 3.9e-02
10 Adipose gene expression Baiap2l2 0.08 0.04 6.3e-05 0.01 0.04 0.03 0.03 1.3e-02 6.8e-05 2.3e-04 4.5e-04
11 OFC intron excision ratio chr7_110824813_110824964 0.24 0.11 1.4e-03 0.14 0.1 0.04 0.11 3.5e-04 3.0e-03 4.2e-02 1.6e-03
12 PL isoform ratio XR_005486728.1 0.03 0.02 6.6e-03 0.03 0.01 0.02 0.02 8.1e-04 1.1e-02 2.8e-03 4.2e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.00.00.3-0.2-0.1-0.0-0.0-0.20.6-0.0-0.1-0.1-0.20.30.0
Area under the delay curve2.32.54.6-1.6-1.7-1.7-1.7-1.52.0-1.3-1.92.1-1.0-1.30.0
BMI with tail0.10.20.80.90.2-0.2-0.00.40.5-0.1-0.20.5-0.7-0.70.0
BMI without tail0.40.92.0-0.4-0.9-1.3-1.4-0.90.7-1.3-0.21.0-1.4-0.60.0
Body weight0.83.510.73.32.12.12.12.2-1.52.11.2-1.91.20.30.0
Weight adjusted by age1.31.54.00.71.71.61.71.4-2.00.90.7-1.00.80.50.0
Bone surface0.10.10.40.50.2-0.0-0.00.2-0.30.1-0.60.50.2-0.50.0
Bone volume0.00.00.1-0.0-0.1-0.3-0.3-0.30.1-0.3-0.10.2-0.20.10.0
Breakpoint value in progressive ratio session0.91.02.7-0.6-1.3-1.3-1.3-1.21.7-1.0-0.40.7-1.1-0.30.0
Number of licking bursts0.70.82.0-1.4-1.1-1.2-1.2-1.00.3-1.20.20.3-0.50.80.0
Context. condit. distance diff. score2.32.75.11.71.92.32.31.6-2.31.21.8-1.70.40.50.0
Locomotion velocity, session 11.11.22.60.81.10.90.91.4-1.41.4-1.10.21.6-0.90.0
Locomotion distance, session 11.72.25.5-1.8-1.3-1.7-1.7-1.00.3-1.4-2.12.3-0.5-1.60.0
Locomotion velocity, session 20.81.04.70.80.70.0-0.01.1-0.80.3-1.51.30.2-2.20.0
Locomotion distance, session 22.23.17.6-1.6-1.8-1.9-1.9-1.41.6-1.3-2.82.5-0.3-1.80.0
Locomotion velocity, session 31.11.37.80.71.41.31.31.0-2.80.40.8-0.5-0.00.50.0
Locomotion distance, session 31.11.22.8-1.7-0.9-1.1-1.1-1.2-0.9-1.60.80.5-1.50.90.0
Stereotopy head waving bouts, day 30.81.02.31.41.01.11.11.3-0.41.5-0.5-0.71.4-0.10.0
Stereotopy head waving duration, day 33.84.58.22.82.72.52.52.9-1.72.8-0.0-1.62.30.00.0
Locomotion velocity, session 70.70.81.40.51.11.11.11.0-1.00.70.8-1.20.90.80.0
Locomotion distance, session 70.60.82.5-0.30.41.11.10.40.01.00.3-1.21.61.10.0
Stereotopy head waving bouts, day 74.14.610.82.73.12.32.33.2-3.32.00.3-1.01.3-0.70.0
Stereotopy head waving duration, day 72.53.08.72.12.71.81.82.6-2.91.30.3-0.50.4-0.70.0
Locomotion velocity, session 82.22.65.21.92.01.91.92.3-2.11.8-0.6-0.41.6-0.80.0
Locomotion distance, session 80.40.61.60.51.01.11.10.9-1.30.4-0.00.00.1-0.70.0
Degree of sensitization distance3.73.78.51.91.82.62.61.90.32.80.0-2.12.90.30.0
Degree of sensitization stereotypy3.13.311.42.02.71.81.82.8-3.41.30.0-0.20.5-1.10.0
Conditioned locomotion0.91.01.70.91.31.11.11.3-1.01.20.7-1.21.20.50.0
Cocaine response after cond. corrected0.60.71.41.20.80.80.81.0-0.10.9-1.10.20.9-0.90.0
Cocaine response after cond. not corrected0.30.31.00.90.40.30.30.60.20.4-1.00.50.3-1.00.0
Cocaine response before conditioning0.91.02.1-1.0-1.2-1.4-1.4-1.20.6-1.30.50.5-1.50.00.0
Saline control response0.20.31.10.30.50.70.80.1-1.10.10.6-0.5-0.30.20.0
Bone: connectivity density0.20.30.60.30.50.70.80.3-0.30.60.4-0.70.60.60.0
Bone: cortical apparent density0.71.04.4-1.2-0.3-0.3-0.5-0.7-0.6-1.12.1-0.8-1.01.30.0
Bone: cortical area0.10.21.21.10.4-0.0-0.10.60.20.6-0.0-0.20.7-0.20.0
Bone: cortical porosity1.01.13.82.00.80.90.91.30.01.2-1.60.21.0-1.00.0
Bone: cortical porosity1.71.96.22.50.91.00.91.5-0.11.5-2.20.41.3-1.50.0
Bone: cortical thickness1.11.83.7-0.8-1.8-1.9-1.9-1.71.9-1.3-0.00.9-1.10.20.0
Bone: cortical thickness1.82.04.7-1.3-2.0-2.2-2.0-1.61.9-1.3-0.51.1-0.9-0.00.0
Bone: cortical tissue density0.70.94.3-1.2-0.2-0.2-0.4-0.6-0.7-0.92.1-0.8-0.81.30.0
Condit. Reinf. active minus inactive responses0.40.41.0-0.6-1.0-0.6-0.6-0.90.3-0.30.5-0.6-0.01.00.0
Condit. Reinf. active-inactive response ratio0.20.20.6-0.1-0.3-0.1-0.1-0.4-0.6-0.10.8-0.7-0.10.70.0
Condit. Reinf. active responses1.11.43.0-1.5-1.5-0.9-0.9-1.70.9-0.91.2-0.8-0.71.70.0
Condit. Reinf. inactive responses1.61.94.1-2.0-1.4-0.8-0.8-2.01.4-1.31.5-0.6-1.22.00.0
Incentive salience index mean0.70.82.8-0.9-1.0-0.7-0.7-1.10.5-0.41.2-1.10.11.70.0
Condit. Reinf. lever presses1.01.34.6-1.0-1.0-0.9-0.8-1.21.0-0.71.8-1.3-0.02.20.0
Condit. Reinf. active minus inactive responses0.40.53.0-0.3-0.7-0.2-0.3-0.31.00.0-1.70.90.3-0.80.0
Condit. Reinf. active-inactive response ratio0.30.31.80.4-0.10.30.20.30.70.6-1.30.30.8-0.60.0
Condit. Reinf. active responses0.50.74.20.3-0.3-0.0-0.10.10.40.2-2.11.20.3-1.40.0
Condit. Reinf. inactive responses0.20.31.1-0.0-0.3-0.5-0.5-0.1-0.2-0.2-1.00.9-0.1-0.80.0
Condit. Reinf. lever presses0.50.71.5-1.2-1.0-0.7-0.9-1.11.2-0.7-0.70.4-0.30.40.0
Condit. Reinf. lever reinforcers received0.40.63.70.3-0.10.10.10.30.40.4-1.90.90.6-1.20.0
Conditioned reinforcement - actives1.31.33.0-0.8-1.5-1.3-1.3-1.21.1-0.8-1.71.7-0.6-0.60.0
Conditioned reinforcement - inactives1.82.14.9-1.5-2.2-1.7-1.7-2.12.2-1.1-0.60.6-0.60.80.0
Conditioned locomotion0.91.14.90.7-1.0-0.7-0.7-0.51.4-0.1-2.21.5-0.2-0.90.0
Patch foraging indifference point 0 sec0.30.62.40.10.20.60.6-0.20.00.50.7-1.30.91.60.0
Patch foraging indifference point AUC0.91.12.5-1.2-1.6-1.2-1.2-1.20.8-0.9-1.40.90.00.30.0
Delay disc. indifference point, 0s delay0.50.53.20.7-0.6-0.7-0.6-0.51.8-0.0-0.70.5-0.4-0.70.0
Delay disc. indifference point, 16s delay2.22.24.5-1.3-1.6-1.6-1.5-1.31.7-1.2-2.12.1-0.7-1.30.0
Delay disc. indifference point, 2s delay5.66.214.8-1.3-2.1-2.7-2.6-1.72.7-2.1-3.23.8-2.2-3.10.0
Delay disc. indifference point, 24s delay0.40.41.50.10.60.60.70.4-1.10.40.1-0.41.20.60.0
Delay disc. indifference point, 4s delay1.31.44.5-0.7-0.9-0.9-1.0-0.61.5-0.5-2.11.8-0.4-1.50.0
Delay disc. indifference point, 8s delay1.81.94.3-2.1-1.8-1.6-1.6-1.81.9-1.1-0.70.9-0.60.10.0
Indifference point function ln k1.31.83.92.01.91.61.61.5-1.51.01.4-1.00.1-0.40.0
Indifference point function log k1.31.83.92.01.91.61.61.5-1.51.01.4-1.00.1-0.40.0
Patch foraging total patch changes 0 sec0.20.31.9-0.4-0.30.10.1-0.70.40.00.5-0.90.51.40.0
Patch foraging total patch changes 12 sec0.10.21.00.2-0.4-0.0-0.0-0.20.20.4-0.80.11.00.10.0
Patch foraging total patch changes 18 sec0.40.51.7-0.2-0.8-0.3-0.2-0.50.90.2-0.9-0.41.31.10.0
Patch foraging total patch changes 24 sec1.01.22.5-1.5-1.6-1.3-1.3-1.51.1-0.90.0-0.2-0.01.60.0
Patch foraging total patch changes 6 sec0.30.40.9-0.6-0.8-0.5-0.4-0.70.90.1-0.7-0.10.80.90.0
Patch foraging time to switch 0 sec0.50.82.90.90.60.30.30.90.70.8-1.51.00.2-1.70.0
Patch foraging water rate 0 sec1.11.87.6-0.30.20.70.7-0.2-0.60.42.1-2.51.22.80.0
Patch foraging water rate 12 sec0.50.74.5-0.4-0.1-0.5-0.5-0.3-0.5-0.62.1-1.2-0.41.10.0
Patch foraging water rate 18 sec1.01.44.30.10.50.50.50.3-1.30.62.0-2.01.12.10.0
Patch foraging water rate 24 sec1.62.24.71.51.51.61.51.4-1.81.51.8-2.21.10.90.0
Patch foraging water rate 6 sec1.01.55.7-0.8-0.5-0.4-0.5-1.0-0.3-0.82.4-1.8-0.42.30.0
Seeking ratio, delayed vs. immediate footshock0.20.20.7-0.90.2-0.10.10.5-0.4-0.3-0.80.7-0.3-0.30.0
Distance traveled before self-admin1.61.75.1-0.8-1.1-1.1-1.2-0.82.0-0.6-2.31.9-0.4-1.40.0
Distance traveled after self-admin0.70.83.60.70.20.70.90.50.51.5-1.0-0.71.90.40.0
Extensor digitorum longus weight0.62.64.8-1.6-1.5-1.9-1.9-1.42.2-1.7-1.01.8-2.1-0.80.0
Bone: elastic displacement0.91.02.00.81.31.21.31.4-1.01.10.1-0.81.00.60.0
Bone: elastic work2.32.96.02.41.81.71.72.5-0.72.3-1.1-0.72.2-1.00.0
Bone: endosteal estimation1.73.77.32.72.42.12.02.6-1.72.3-0.9-0.82.3-0.90.0
Bone: endosteal perimeter1.83.88.52.92.62.02.02.8-2.02.2-0.5-0.92.0-1.00.0
Epididymis fat weight0.71.56.02.51.31.21.31.2-1.61.01.1-0.8-0.0-0.80.0
Delta time in closed arm before/after self-admin0.20.20.70.2-0.8-0.5-0.6-0.60.8-0.2-0.50.5-0.2-0.20.0
Delta time in open arm before/after self-admin0.10.10.4-0.3-0.3-0.3-0.2-0.20.3-0.1-0.60.4-0.2-0.00.0
Diff in mean of infusions in LGA sessions0.20.20.7-0.6-0.8-0.7-0.5-0.70.4-0.30.0-0.10.10.60.0
Delay discount exponential model param2.42.54.61.61.71.81.71.5-1.91.31.9-2.21.01.20.0
Extinction: sum of active levers before priming1.81.84.2-0.9-1.2-1.7-1.5-1.01.3-1.3-1.52.1-1.1-1.40.0
Active lever presses in extinction session 60.10.10.20.30.10.10.10.20.20.2-0.40.10.3-0.40.0
Bone: final force0.60.92.51.60.70.50.41.20.11.2-1.00.01.5-1.10.0
Bone: final moment0.71.23.01.71.00.80.71.4-0.01.5-1.0-0.21.7-1.00.0
Food consumed during 24 hour testing period0.20.31.71.3-0.2-0.2-0.10.10.40.1-1.00.40.3-0.50.0
Glucose0.30.51.70.4-0.3-0.1-0.2-0.31.00.31.1-1.20.31.30.0
Heart weight1.72.47.01.61.21.31.31.0-1.01.42.5-2.61.21.70.0
Delay discount hyperbolic model param2.93.06.01.51.81.91.91.6-2.11.42.2-2.41.21.60.0
Intermittent access intake day 1-15 change0.60.61.4-1.1-1.0-1.0-1.0-1.20.6-1.00.40.1-0.60.50.0
Intermittent access intake escalation1.11.12.2-1.2-1.3-1.4-1.4-1.50.9-1.30.30.4-1.00.30.0
Intermittent access intake escalation 20.70.71.6-0.9-1.1-1.0-1.0-1.30.8-0.90.6-0.1-0.70.70.0
Intermitt. access day 1 inactive lever presses0.70.82.90.60.61.01.00.70.11.4-0.3-0.91.70.40.0
Intermitt. access day 15 inactive lever presses0.20.21.00.1-0.10.30.3-0.10.50.6-0.0-0.51.00.40.0
Intermitt. access escalation Index0.50.51.1-0.4-0.7-0.9-0.9-0.60.3-1.1-0.20.8-0.9-0.40.0
Intermittent access day 1 total infusions0.91.06.40.8-0.5-0.2-0.20.20.30.3-2.51.60.4-1.30.0
Intermittent access day 15 total infusions0.70.72.6-0.2-1.2-0.9-0.9-0.80.9-0.4-1.61.10.1-0.60.0
Intermittent access terminal intake (last 3 days)0.40.41.8-0.3-0.8-0.7-0.7-0.50.3-0.3-1.31.10.1-0.50.0
Intermittent access total infusions1.11.26.60.1-0.9-0.7-0.7-0.31.0-0.1-2.61.70.3-1.30.0
Intermittent access day 1 locomotion0.30.42.10.5-0.5-0.2-0.2-0.20.80.4-1.40.70.5-0.40.0
Intermittent access day 15 total locomotion0.20.20.6-0.0-0.8-0.6-0.6-0.70.7-0.2-0.40.2-0.10.20.0
Intermittent access total locomotion0.30.31.40.6-0.8-0.2-0.2-0.51.20.4-0.9-0.10.60.30.0
Intermittent access standard deviation0.60.72.50.7-1.0-0.6-0.6-0.71.60.3-1.40.50.6-0.40.0
Left kidney weight4.312.227.15.24.14.14.24.3-3.84.30.5-2.43.2-0.40.0
Right kidney weight4.813.432.25.73.74.44.43.9-3.04.81.1-3.63.90.60.0
Cocaine induced anxiety0.30.31.00.71.00.80.81.0-0.20.6-0.1-0.2-0.0-0.20.0
Post-drug Anxiety3.64.07.41.42.72.72.72.4-1.72.31.3-2.21.80.90.0
Baseline Anxiety1.11.23.9-0.50.70.90.90.2-0.70.52.0-1.90.91.70.0
Tail length0.20.62.70.40.00.30.1-0.3-0.50.21.6-1.50.21.40.0
Length with tail1.65.89.73.12.52.92.62.3-2.42.72.1-3.12.21.30.0
Length without tail2.65.79.83.12.53.03.02.6-2.23.01.1-2.42.40.70.0
Times rat made contact with spout1.41.64.3-1.0-1.6-1.3-1.3-1.80.4-1.11.4-1.1-0.12.10.0
Lifetime Intake1.11.37.30.4-0.9-0.6-0.6-0.21.10.1-2.71.60.5-1.40.0
Liver weight, left1.11.84.52.01.81.31.31.9-2.11.2-0.3-0.20.6-0.80.0
Liver weight, right1.42.46.92.12.11.71.71.8-2.61.41.2-1.10.2-0.10.0
Locomotor activity0.50.83.81.90.81.00.80.8-0.70.90.6-0.80.4-0.40.0
Locomotor testing distance0.60.91.9-0.3-1.2-1.2-1.2-1.40.8-1.30.90.1-1.30.20.0
Locomotor testing rearing0.10.21.31.10.10.10.10.3-0.50.2-0.00.1-0.1-1.00.0
Locomotion in novel chamber1.72.15.7-2.4-1.1-1.4-1.2-1.60.0-1.91.60.1-2.11.30.0
Locomotion in novel chamber post-restriction2.73.26.4-1.8-2.1-2.5-2.2-1.91.3-2.2-0.81.9-2.1-0.90.0
Fecal boli incidents, locomotor time 10.50.63.4-0.4-0.30.10.40.30.30.8-0.8-0.71.80.80.0
Change in fecal boli incidents, locomotor task0.60.62.90.50.80.50.40.2-1.4-0.21.7-0.5-0.30.40.0
Time >=10cm from walls, locomotor time 10.80.82.11.40.91.01.10.9-0.21.3-0.9-0.51.2-0.10.0
Bouts of movement, locomotor time 10.10.10.50.70.20.20.00.2-0.40.10.2-0.40.30.10.0
Total resting periods, locomotor time 10.10.20.50.60.50.50.30.4-0.10.40.0-0.50.70.20.0
Rest time, locomotor task time 10.60.72.30.40.41.00.80.50.11.10.1-1.21.51.20.0
Distance moved, locomotor task time 10.40.41.70.80.80.50.60.7-1.30.10.7-0.0-0.5-0.40.0
Vertical activity count, locomotor time 10.80.93.70.30.10.30.4-0.30.00.31.7-1.80.11.90.0
Time >=10cm from walls, locomotor time 22.02.14.01.01.61.41.91.5-1.21.40.7-2.02.01.60.0
Bouts of movement, locomotor time 22.42.55.0-0.4-1.6-2.2-2.2-1.31.5-1.9-0.61.9-2.1-1.50.0
Total resting periods, locomotor time 22.83.05.9-0.5-1.8-2.3-2.4-1.31.8-1.9-1.12.3-2.0-1.70.0
Rest time, locomotor task time 20.10.10.6-0.2-0.4-0.1-0.4-0.20.80.1-0.60.10.30.20.0
Distance moved, locomotor task time 21.01.22.31.01.41.21.41.1-1.50.91.1-1.20.70.50.0
Vertical activity count, locomotor time 21.11.24.40.80.70.71.20.4-0.50.91.5-2.11.01.60.0
Light reinforcement 10.00.10.20.30.40.30.20.4-0.40.1-0.30.20.1-0.30.0
Light reinforcement 20.20.20.60.80.40.10.10.4-0.6-0.2-0.20.5-0.7-0.70.0
Bone: marrow area1.94.17.92.82.52.22.12.8-1.92.4-0.9-0.82.4-0.90.0
Bone: maximum diameter1.83.410.13.22.31.61.62.6-1.42.3-0.4-1.02.2-0.70.0
Bone: maximum force0.81.33.81.91.00.70.71.50.11.6-1.1-0.01.7-0.90.0
Bone: maximum moment1.01.74.52.11.21.01.01.7-0.11.8-1.2-0.22.0-0.90.0
Mean time between licks in bursts0.40.52.2-0.40.5-0.00.10.50.0-0.4-1.21.2-0.4-1.50.0
Mean num. licks in bursts0.20.20.90.7-0.00.30.2-0.3-0.30.30.8-0.90.20.50.0
Cd content in liver0.60.62.60.2-0.1-0.7-0.7-0.0-0.4-1.00.01.1-1.6-1.30.0
Co content in liver0.30.31.10.1-0.6-1.0-0.9-0.40.5-0.5-0.10.4-0.6-0.30.0
Cu content in liver2.12.66.2-2.5-1.6-2.0-2.1-1.71.2-2.0-0.11.3-1.7-0.10.0
Fe content in liver2.42.96.22.52.22.02.02.2-1.71.90.4-1.51.50.40.0
K content in liver0.30.31.5-0.10.10.20.10.20.30.2-1.20.70.4-1.10.0
Mg content in liver0.20.20.80.10.30.40.20.20.20.4-0.90.40.6-0.60.0
Mn content in liver0.91.02.0-1.0-1.1-1.0-1.3-1.10.7-1.3-0.61.2-1.4-0.50.0
Na content in liver0.10.10.2-0.4-0.1-0.2-0.3-0.40.2-0.30.2-0.1-0.1-0.00.0
Rb content in liver0.10.20.8-0.10.10.40.4-0.10.40.20.2-0.50.50.90.0
Se content in liver1.51.85.5-0.9-0.9-1.8-1.9-1.1-0.3-2.10.41.1-2.3-0.60.0
Sr content in liver4.13.76.9-2.6-2.2-2.2-2.2-2.41.9-2.40.11.4-2.40.10.0
Zn content in liver0.40.40.8-0.7-0.5-0.9-0.8-0.3-0.1-0.8-0.40.9-0.7-0.80.0
Bone: minimum diameter0.30.51.81.40.50.50.40.70.00.9-0.8-0.00.9-0.50.0
Time in familiar zone, hab. session 10.20.20.90.10.60.10.20.8-0.60.4-0.3-0.21.00.10.0
Time in novel zone, hab. session 10.30.31.21.10.50.80.80.4-0.50.40.3-0.2-0.3-0.30.0
Total zone transitions, hab. session 11.52.24.9-2.1-1.4-1.6-1.7-1.70.1-2.2-0.11.4-2.0-0.10.0
Total locomotion distance, hab. session 10.71.12.7-1.2-1.0-1.1-1.2-1.3-0.4-1.70.50.6-1.60.10.0
Locomotion velocity, hab. session 10.91.22.8-1.4-1.2-1.3-1.3-1.50.0-1.70.40.7-1.50.20.0
Time in familiar zone, hab. session 20.40.41.0-0.6-0.0-0.6-0.6-0.3-0.8-0.71.0-0.2-0.80.80.0
Time in novel zone, hab. session 20.40.41.70.4-0.8-0.0-0.1-0.51.30.2-1.00.50.2-0.70.0
Total zone transitions, hab. session 20.40.51.2-1.1-0.9-0.8-0.8-0.90.4-0.5-0.90.50.40.50.0
Total locomotion distance, hab. session 20.30.42.3-0.3-0.7-0.6-0.6-0.50.5-0.2-1.50.80.5-0.20.0
Locomotion velocity, hab. session 20.30.41.7-0.5-0.7-0.6-0.6-0.60.6-0.2-1.30.60.60.10.0
Novel to familiar place preference ratio0.80.82.91.51.01.00.91.0-1.70.50.7-0.4-0.2-0.40.0
Novelty place preference1.01.03.61.61.11.00.91.0-1.90.41.0-0.5-0.4-0.30.0
Time in novel zone, NPP test1.01.03.91.61.11.01.01.0-2.00.41.1-0.6-0.4-0.20.0
Total zone transitions, NPP test1.11.64.6-2.1-1.3-1.6-1.6-1.50.1-1.8-0.51.2-1.00.20.0
Total locomotion distance, NPP test0.10.20.6-0.8-0.2-0.2-0.3-0.3-0.4-0.3-0.80.60.3-0.20.0
Locomotion velocity, NPP test0.30.41.5-1.2-0.5-0.6-0.7-0.6-0.1-0.7-0.80.8-0.0-0.10.0
Intraocular pressure0.30.40.90.90.70.70.70.9-0.80.6-0.50.00.6-0.70.0
Delta distance traveled before/after self-admin3.23.57.01.61.52.02.21.5-1.92.21.4-2.62.31.80.0
Delta ambulatory time before/after self-admin3.63.97.31.91.72.22.41.8-2.12.51.0-2.52.71.40.0
Parametrial fat weight0.61.26.5-0.10.10.30.1-0.4-0.1-0.22.5-1.9-0.12.00.0
Pavlov. Cond. lever latency0.20.20.60.60.40.80.70.4-0.30.5-0.60.10.2-0.30.0
Pavlov. Cond. magazine entry latency0.81.12.5-0.8-1.2-1.4-1.4-0.71.6-0.9-1.01.2-0.3-0.70.0
Pavlov. Cond. change in total contacts1.31.32.6-0.9-1.5-1.6-1.5-1.11.5-0.9-1.31.2-0.1-0.60.0
Pavlov. Cond. index score0.20.20.7-0.3-0.6-0.8-0.8-0.30.8-0.2-0.30.20.4-0.20.0
Pavlov. Cond. latency score0.10.10.4-0.1-0.5-0.7-0.6-0.20.7-0.1-0.10.10.3-0.10.0
Pavlov. Cond. lever contacts0.20.20.6-0.7-0.6-0.7-0.7-0.40.8-0.40.1-0.10.20.40.0
Pavlov. Cond. magazine entry number0.50.71.50.81.01.21.20.7-1.00.70.7-0.90.20.40.0
Pavlov. Cond. intertrial magazine entries0.40.51.9-0.8-0.40.30.3-0.80.30.11.2-1.10.31.40.0
Pavlov. Cond. lever-magazine prob. diff.0.30.30.9-0.6-0.8-1.0-0.9-0.50.9-0.5-0.20.30.1-0.10.0
Pavlov. Cond. response bias0.50.61.7-0.8-1.0-1.2-1.1-0.61.3-0.5-0.50.40.2-0.00.0
Pavlov. Cond. lever latency0.20.31.00.0-0.5-0.7-0.6-0.3-0.2-0.4-0.00.9-0.7-1.00.0
Pavlov. Cond. magazine entry latency0.70.83.0-1.2-1.2-0.8-0.8-1.11.7-0.6-0.70.30.00.50.0
Pavlov. Cond. change in total contacts2.02.77.81.41.72.12.01.9-0.12.2-0.4-1.62.80.80.0
Pavlov. Cond. index score0.20.31.1-0.7-0.20.20.1-0.20.90.2-0.3-0.60.81.00.0
Pavlov. Cond. latency score0.30.41.7-0.8-0.30.20.1-0.31.10.2-0.1-0.80.91.30.0
Pavlov. Cond. lever contacts0.20.31.6-0.30.30.50.40.10.20.20.3-1.00.61.30.0
Pavlov. Cond. magazine entry number0.20.20.80.70.3-0.1-0.00.3-0.9-0.10.10.4-0.5-0.90.0
Pavlov. Cond. intertrial magazine entries0.10.20.40.1-0.30.00.1-0.20.50.30.6-0.60.60.60.0
Pavlov. Cond. lever-magazine prob. diff.0.20.20.8-0.6-0.10.20.1-0.20.90.1-0.2-0.50.60.90.0
Pavlov. Cond. response bias0.10.20.6-0.30.20.30.20.20.60.3-0.5-0.40.80.70.0
Time in closed arm before self-admin0.70.73.7-0.8-1.0-0.9-0.9-1.01.9-0.5-0.60.3-0.30.20.0
Time in closed arm after self-admin0.30.31.00.6-0.20.30.3-0.30.80.50.5-1.00.51.00.0
Time in open arm before self-admin0.60.71.8-0.20.90.90.80.5-1.30.51.3-1.00.50.70.0
Time in open arm after self-admin0.30.30.7-0.9-0.2-0.5-0.5-0.6-0.1-0.70.8-0.1-0.70.50.0
Bone: periosteal estimation1.12.36.32.51.81.41.32.1-1.01.9-0.7-0.51.9-0.80.0
Bone: periosteal perimeter2.13.69.73.12.31.71.82.6-1.72.3-0.1-1.22.2-0.50.0
Bone: post-yield work0.10.20.70.50.3-0.20.00.50.10.4-0.70.50.8-0.20.0
Progressive ratio test 1 active lever presses0.80.84.5-0.2-1.0-0.6-0.6-0.51.2-0.0-2.11.20.3-0.60.0
Progressive ratio test 1 breakpoint0.40.42.4-0.3-0.7-0.4-0.4-0.40.70.0-1.50.80.4-0.30.0
Progressive ratio test 1 inactive lever presses1.11.24.2-0.6-1.1-0.8-0.8-0.62.0-0.3-2.01.4-0.3-0.60.0
Progressive ratio test 2 active lever presses1.11.23.0-1.1-1.7-1.3-1.3-1.51.4-0.9-1.10.8-0.20.30.0
Progressive ratio test 2 breakpoint0.70.71.8-0.8-1.3-0.9-0.9-1.11.2-0.4-1.30.70.20.10.0
Progressive ratio test 2 inactive lever presses1.61.83.4-1.7-1.8-1.6-1.6-1.61.7-1.1-1.31.3-0.4-0.00.0
Incentive Sensitization - Responses0.60.61.4-1.1-1.0-0.9-0.9-1.20.4-0.90.30.0-0.60.80.0
Incentive Sensitization - Breakpoint0.60.61.4-1.1-1.1-0.9-0.9-1.20.4-0.90.20.0-0.60.80.0
Sum of active levers in priming session hrs 5-60.10.11.0-0.2-0.2-0.2-0.2-0.11.00.0-0.60.3-0.1-0.30.0
Progressive ratio0.20.21.10.00.00.40.30.10.40.5-1.00.30.4-0.20.0
Food seeking constrained by brief footshock0.30.31.10.6-0.3-0.9-0.6-0.00.0-0.3-0.50.8-0.3-1.00.0
Seeking ratio, punishment vs. effort0.10.10.70.1-0.3-0.8-0.5-0.10.0-0.40.30.2-0.2-0.30.0
Retroperitoneal fat weight1.96.214.63.82.92.72.82.8-2.62.62.2-2.71.60.40.0
Reaction time number correct0.71.12.8-1.3-0.7-1.3-1.3-0.8-0.9-1.70.30.9-1.5-0.00.0
Reaction time mean minus median0.00.00.20.10.20.40.40.2-0.00.3-0.2-0.00.20.10.0
Reaction time mean minus median AUC0.10.10.30.40.20.50.50.20.00.40.2-0.30.00.10.0
Reaction time num false alarms0.10.10.30.3-0.4-0.4-0.3-0.40.0-0.40.4-0.0-0.5-0.00.0
Reaction time num false alarms AUC0.10.10.40.1-0.5-0.4-0.4-0.5-0.1-0.60.40.2-0.6-0.30.0
Reaction time trials correct on left0.71.12.8-1.3-0.7-1.3-1.3-0.8-0.9-1.70.30.9-1.5-0.00.0
Reaction time trials on left0.91.23.2-1.3-0.8-1.4-1.4-0.9-0.9-1.80.31.0-1.6-0.10.0
Reaction time mean0.40.61.30.20.91.21.10.8-0.10.90.7-0.80.60.70.0
Reaction time mean AUC0.20.30.80.10.70.90.90.6-0.10.70.5-0.50.40.60.0
Median of all reaction times0.40.51.20.10.91.11.10.8-0.00.90.6-0.70.70.60.0
Reaction time omissions2.02.77.2-0.8-1.4-1.7-1.7-1.11.3-1.6-2.02.7-1.7-2.10.0
Reaction time false alarm rate0.10.10.30.5-0.20.20.2-0.20.50.00.3-0.2-0.1-0.20.0
Reaction time premature initiation rate0.30.41.61.30.20.30.30.40.60.9-0.5-0.41.0-0.10.0
Reaction time premature initiations0.00.10.40.6-0.2-0.2-0.2-0.10.20.1-0.3-0.10.30.10.0
Std. dev. reaction times0.30.40.80.80.60.90.90.5-0.20.70.4-0.60.40.40.0
Reaction time trials completed0.91.23.2-1.3-0.8-1.4-1.4-0.9-0.9-1.80.31.0-1.6-0.10.0
Reaction time trials AUC0.60.92.3-1.0-0.6-1.2-1.2-0.8-1.0-1.50.30.9-1.4-0.10.0
Run reversals in cocaine runway, females0.80.73.3-0.50.70.50.50.1-1.2-0.41.8-1.0-0.41.20.0
Run reversals in cocaine runway, males0.50.41.60.60.51.00.50.3-1.30.7-0.60.20.7-0.70.0
Latency to leave start box in cocaine runway1.11.22.81.21.51.20.81.7-1.00.7-0.80.70.1-1.70.0
Latency to leave start box in cocaine runway, F0.80.93.70.51.20.60.61.4-0.70.3-1.01.10.0-1.90.0
Latency to leave start box in cocaine runway, M0.40.41.51.20.70.90.30.8-0.70.4-0.20.3-0.3-0.60.0
Std. dev. time between licks in bursts0.30.41.2-0.00.50.70.70.7-0.20.8-0.6-0.31.1-0.30.0
Total sessions with >9 infusions0.30.31.80.8-0.40.10.10.00.40.6-1.30.30.8-0.30.0
Short access day 1 total inactive lever presses1.01.13.40.90.41.11.10.90.51.5-1.8-0.01.9-0.20.0
Short access day 10 total inactive lever presses2.02.26.20.91.11.61.60.8-1.01.61.7-2.51.81.70.0
Short access day 1 total infusions0.30.41.30.60.00.50.50.30.30.8-1.10.01.1-0.10.0
Short access day 10 total infusions1.01.16.41.1-0.3-0.1-0.10.30.60.6-2.51.40.7-1.50.0
Short access total infusions0.91.05.31.20.00.40.40.70.41.0-2.30.81.3-1.20.0
Short access day 1 locomotion0.50.53.20.3-0.6-0.2-0.2-0.20.90.3-1.80.80.6-0.40.0
Short access day 10 total locomotion1.31.47.1-0.3-1.8-1.2-1.2-1.72.7-0.4-0.5-0.1-0.00.90.0
Short access total locomotion0.50.61.90.8-0.50.10.1-0.21.40.9-1.3-0.11.10.30.0
One hour access (0.3 mA shock)3.64.27.0-1.9-2.7-2.6-2.6-2.12.1-2.1-2.02.5-1.4-1.10.0
Compulsive drug intake2.22.24.2-2.0-1.8-1.5-1.5-2.01.5-1.51.3-0.3-1.21.50.0
One hour access (shock baseline)0.80.92.8-0.2-0.9-1.0-1.0-0.50.6-0.7-1.71.7-0.5-1.20.0
Social response proportion1.41.55.41.31.00.60.71.40.10.5-2.31.40.1-2.30.0
Social responses0.40.62.80.1-0.2-0.2-0.30.00.4-0.4-1.71.3-0.1-1.30.0
Social time1.41.94.2-1.5-1.7-1.6-1.6-1.32.1-1.2-1.51.4-0.6-0.70.0
Soleus weight1.02.98.3-1.5-2.1-1.5-1.5-2.12.5-0.61.3-1.50.42.90.0
Bone: stiffness0.71.13.21.81.11.00.91.40.11.4-0.2-0.71.7-0.10.0
Tibialis anterior weight2.37.814.9-3.1-3.4-3.3-3.4-3.23.9-2.8-1.62.6-2.6-0.10.0
Time to tail flick, vehicle, before self-admin0.00.00.20.4-0.3-0.1-0.0-0.20.0-0.1-0.20.2-0.3-0.00.0
Time to tail flick, vehicle, after self-admin0.40.41.70.10.30.40.50.1-0.60.11.2-1.00.11.30.0
Time to tail flick, test, before self-admin1.21.22.3-1.1-1.2-1.3-1.5-1.10.6-1.3-0.61.4-1.3-0.60.0
Time to tail flick, test, after self-admin0.40.51.5-1.2-0.2-0.4-0.4-0.6-0.3-0.71.0-0.2-0.41.20.0
Delta time to tail flick, vehicle, before/after SA0.10.10.4-0.10.30.30.30.3-0.10.30.1-0.20.60.10.0
Delta time to tail flick, test, before/after SA0.80.73.0-0.9-0.0-0.2-0.2-0.6-0.3-0.81.7-0.8-0.61.50.0
Tibia length0.41.12.71.71.31.01.01.5-0.71.5-0.1-0.61.4-0.20.0
Ambulatory time before self-admin1.71.84.2-1.4-1.6-1.4-1.5-1.52.0-1.1-1.31.5-0.9-0.50.0
Ambulatory time after self-admin0.30.41.90.3-0.10.40.50.10.31.0-0.5-0.71.40.50.0
Bone: tissue strength0.20.20.70.80.50.60.60.50.00.4-0.2-0.30.3-0.00.0
Total heroin consumption1.11.32.7-0.3-1.2-1.4-1.5-1.00.8-1.0-1.31.6-1.1-1.40.0
Bone: trabecular number0.10.20.50.20.50.40.50.3-0.70.20.7-0.4-0.20.40.0
Bone: trabecular spacing0.40.52.20.90.50.50.60.70.20.9-0.5-0.61.50.50.0
Bone: trabecular thickness0.20.20.6-0.7-0.3-0.2-0.2-0.60.3-0.40.8-0.3-0.60.60.0
Bone: trabecular tissue density0.30.41.9-0.6-0.10.2-0.0-0.30.4-0.21.4-1.0-0.21.10.0
Water consumed over 24 hours0.20.30.7-0.0-0.8-0.6-0.7-0.90.2-0.40.5-0.40.10.80.0
Number of responses in last shaping day3.33.411.1-0.5-1.9-1.8-1.8-1.02.2-0.9-3.32.9-0.6-2.10.0