Bahd1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	BLA	mRNA stability	Bahd1	0.12	0.08	2.3e-03	0.05	0.01	0.04	0.02	1.0e-03	1.0e-01	4.6e-03	2.5e-02
2	Brain	gene expression	Bahd1	0.09	0.05	1.4e-06	0.07	0.07	0.07	0.07	1.9e-07	1.9e-07	5.4e-07	5.3e-07
3	pVTA	gene expression	Bahd1	0.04	0.03	7.8e-03	0	0	0	0	1.5e-01	1.1e-01	2.3e-01	3.2e-01
4	Adipose	gene expression	Bahd1	0.06	0.03	2.4e-06	0.01	0.03	0.02	0.02	2.9e-02	2.8e-04	2.5e-03	3.3e-03
5	NAcc	gene expression	Bahd1	0.05	0.03	9.7e-04	0.03	0.02	0.03	0.03	2.1e-05	1.1e-04	1.6e-05	2.0e-05
6	pVTA	mRNA stability	Bahd1	0.04	0.02	5.7e-03	0	0.01	0.02	0.01	2.5e-01	4.4e-02	1.8e-02	3.4e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6
Bone: apparent density	0.5	0.9	1.8	-1.0	1.3	-0.9	-1.0	0.4	-0.9
Area under the delay curve	1.2	1.9	5.1	-0.9	1.2	-1.9	0.2	2.3	0.5
BMI with tail	1.8	6.3	21.7	-4.7	3.4	-1.3	-1.3	0.6	-1.0
BMI without tail	2.1	11.2	29.8	-5.5	4.4	-2.1	-2.7	0.7	-2.5
Body weight	2.0	8.5	30.4	-5.5	3.8	-1.5	-1.4	0.7	-1.3
Weight adjusted by age	0.1	0.3	1.3	-1.1	0.5	0.0	0.5	0.3	-0.3
Bone surface	0.4	0.8	1.4	-1.1	0.9	0.1	-1.0	-0.8	-1.2
Bone volume	0.5	0.9	1.4	-1.2	1.1	-0.1	-1.0	-0.8	-1.1
Breakpoint value in progressive ratio session	0.1	0.2	0.5	0.5	0.0	0.1	-0.4	-0.3	-0.7
Number of licking bursts	0.1	0.4	0.9	0.6	0.1	-0.1	-1.0	-0.6	-0.9
Context. condit. distance diff. score	2.1	2.6	4.4	-1.6	2.1	-0.5	-1.9	-0.7	-2.1
Locomotion velocity, session 1	1.9	2.2	5.9	2.4	-1.4	-0.3	1.2	1.4	1.3
Locomotion distance, session 1	1.0	1.2	3.2	1.8	-0.9	-0.5	0.7	1.5	0.7
Locomotion velocity, session 2	1.6	2.0	5.3	-0.0	1.3	-2.1	-0.5	2.3	-0.1
Locomotion distance, session 2	0.4	0.6	1.7	1.3	-0.1	-0.7	-0.2	1.0	-0.4
Locomotion velocity, session 3	0.4	0.4	1.1	0.7	0.5	-1.0	-0.1	0.8	0.3
Locomotion distance, session 3	0.8	1.0	2.2	0.1	1.0	-0.5	-1.5	-0.5	-1.4
Stereotopy head waving bouts, day 3	0.6	0.8	2.5	-1.6	1.1	-0.6	0.4	0.4	0.5
Stereotopy head waving duration, day 3	1.1	1.4	2.1	-1.4	1.3	-1.5	0.3	1.4	0.8
Locomotion velocity, session 7	0.7	0.7	1.2	-0.6	1.1	-0.7	-1.1	0.1	-1.1
Locomotion distance, session 7	0.7	0.8	2.4	-0.4	0.7	0.2	-1.2	-0.8	-1.6
Stereotopy head waving bouts, day 7	0.4	0.5	0.8	0.4	-0.8	0.6	0.8	-0.5	0.9
Stereotopy head waving duration, day 7	0.6	0.8	1.3	0.1	-0.8	0.9	1.1	-0.7	1.1
Locomotion velocity, session 8	1.8	2.2	4.3	-0.9	2.0	-2.1	-1.0	1.5	-0.7
Locomotion distance, session 8	1.3	1.9	3.8	-0.5	1.7	-1.1	-1.7	0.4	-1.9
Degree of sensitization distance	0.8	0.8	2.0	-0.1	-1.1	1.4	0.8	-1.0	0.3
Degree of sensitization stereotypy	0.8	0.9	2.0	0.2	-1.1	1.4	0.7	-1.3	0.5
Conditioned locomotion	1.4	1.6	2.7	-1.6	1.7	-0.8	-1.3	0.0	-1.5
Cocaine response after cond. corrected	0.6	0.9	2.9	1.7	0.1	-1.0	-1.0	-0.0	-0.6
Cocaine response after cond. not corrected	0.7	1.1	3.9	2.0	-0.0	-1.2	-0.8	0.5	-0.4
Cocaine response before conditioning	0.4	0.5	1.5	0.4	-0.4	-0.2	0.8	1.2	0.8
Saline control response	0.7	1.0	3.6	-1.9	0.2	0.9	1.0	-0.5	0.8
Bone: connectivity density	0.1	0.2	0.6	-0.8	0.0	0.4	0.5	0.1	0.4
Bone: cortical apparent density	1.1	1.8	5.0	0.3	-1.2	2.0	-0.0	-2.2	-0.5
Bone: cortical area	0.4	0.7	2.3	-1.5	1.1	-0.5	-0.5	0.2	-0.4
Bone: cortical porosity	2.4	2.6	6.1	1.5	0.8	-2.5	-0.7	2.4	-0.2
Bone: cortical porosity	1.8	2.0	4.9	0.7	1.1	-2.2	-0.7	2.2	-0.2
Bone: cortical thickness	0.5	0.8	1.4	-1.1	1.2	-1.0	-0.4	0.9	-0.2
Bone: cortical thickness	0.5	0.6	1.1	0.5	0.7	-0.4	-1.1	-0.5	-1.0
Bone: cortical tissue density	1.1	1.7	4.7	0.3	-1.1	2.0	0.0	-2.2	-0.4
Condit. Reinf. active minus inactive responses	2.3	2.6	6.1	-0.3	-1.9	2.5	1.7	-1.4	1.2
Condit. Reinf. active-inactive response ratio	0.7	0.7	1.3	-1.1	-0.4	1.1	0.8	-0.7	0.7
Condit. Reinf. active responses	3.7	4.8	11.1	0.1	-2.7	3.3	2.0	-2.0	1.3
Condit. Reinf. inactive responses	1.9	2.4	5.6	0.7	-2.1	2.4	1.0	-1.8	0.3
Incentive salience index mean	3.1	4.0	7.9	0.4	-2.7	2.8	2.2	-1.1	1.6
Condit. Reinf. lever presses	2.4	3.5	7.2	0.8	-2.7	2.4	2.2	-0.6	1.6
Condit. Reinf. active minus inactive responses	0.9	1.4	3.3	-1.5	-0.4	1.8	0.4	-1.7	-0.1
Condit. Reinf. active-inactive response ratio	0.6	1.0	2.1	-1.3	-0.4	1.4	0.1	-1.4	-0.3
Condit. Reinf. active responses	1.5	2.2	4.8	-2.0	-0.5	2.2	0.7	-1.9	0.1
Condit. Reinf. inactive responses	1.0	1.6	2.9	-1.5	-0.7	1.7	1.3	-1.1	0.9
Condit. Reinf. lever presses	1.7	2.5	4.3	-1.7	-1.0	2.1	1.8	-1.2	1.5
Condit. Reinf. lever reinforcers received	1.8	2.6	6.1	-1.9	-0.9	2.5	1.1	-1.9	0.6
Conditioned reinforcement - actives	0.1	0.4	1.7	0.6	-0.5	-0.4	0.4	1.3	0.2
Conditioned reinforcement - inactives	0.3	0.8	2.3	-0.3	0.8	-0.7	-1.2	0.5	-1.5
Conditioned locomotion	1.0	1.5	2.8	0.2	-0.8	-0.2	1.6	1.7	1.7
Patch foraging indifference point 0 sec	0.9	2.6	6.3	-1.6	-0.3	0.5	2.4	0.9	2.5
Patch foraging indifference point AUC	0.5	1.2	2.9	1.7	-1.5	0.9	0.7	-0.3	0.8
Delay disc. indifference point, 0s delay	1.0	1.1	2.8	-0.1	-0.7	0.0	1.7	1.0	1.6
Delay disc. indifference point, 16s delay	0.7	0.9	2.7	0.2	0.5	-1.5	0.2	1.7	0.5
Delay disc. indifference point, 2s delay	0.4	0.4	2.1	-1.5	0.5	0.2	-0.0	-0.3	-0.1
Delay disc. indifference point, 24s delay	0.7	1.1	1.7	1.3	-0.8	-0.2	1.2	1.3	1.0
Delay disc. indifference point, 4s delay	1.2	1.3	4.4	-0.4	0.8	-1.6	0.1	2.1	0.4
Delay disc. indifference point, 8s delay	1.4	2.3	4.4	-1.5	1.7	-2.1	0.2	2.1	0.5
Indifference point function ln k	1.3	3.9	8.1	-2.2	2.8	-1.8	-1.9	0.5	-1.9
Indifference point function log k	1.3	3.9	8.1	-2.2	2.8	-1.8	-1.9	0.5	-1.9
Patch foraging total patch changes 0 sec	0.7	2.2	5.4	-1.4	-0.3	0.6	2.2	0.6	2.3
Patch foraging total patch changes 12 sec	1.2	1.7	3.5	0.1	-1.4	1.3	1.9	0.0	1.7
Patch foraging total patch changes 18 sec	0.4	1.0	1.7	0.6	-1.3	1.0	1.2	-0.2	1.1
Patch foraging total patch changes 24 sec	0.2	0.7	1.4	-0.8	0.3	-0.4	0.8	1.1	1.2
Patch foraging total patch changes 6 sec	0.7	1.2	2.7	0.1	-1.1	1.0	1.5	0.2	1.6
Patch foraging time to switch 0 sec	0.7	2.6	4.3	0.3	-2.1	1.9	2.0	-0.6	1.7
Patch foraging water rate 0 sec	0.4	1.4	2.2	-1.2	1.4	-0.2	-1.5	-0.9	-1.5
Patch foraging water rate 12 sec	0.6	2.5	5.7	-0.0	1.6	-1.0	-2.4	-0.6	-2.4
Patch foraging water rate 18 sec	0.8	1.8	3.4	-0.2	1.9	-1.7	-1.6	0.5	-1.2
Patch foraging water rate 24 sec	1.5	2.2	4.2	-0.9	1.1	0.3	-1.8	-1.8	-2.1
Patch foraging water rate 6 sec	1.2	1.7	3.7	0.9	0.3	0.2	-1.8	-1.6	-1.9
Seeking ratio, delayed vs. immediate footshock	0.7	1.0	3.0	-0.7	0.5	0.4	-1.2	-0.9	-1.7
Distance traveled before self-admin	0.3	0.6	1.3	-0.7	1.1	-0.8	-0.5	1.0	-0.5
Distance traveled after self-admin	0.1	0.1	0.2	-0.2	0.1	0.5	-0.3	-0.5	-0.5
Extensor digitorum longus weight	0.2	0.6	1.4	-0.6	1.2	-1.1	-0.8	0.3	-0.5
Bone: elastic displacement	0.2	0.3	0.8	0.1	-0.3	-0.1	0.7	0.6	0.9
Bone: elastic work	0.3	0.4	1.0	-1.0	-0.1	0.4	0.6	-0.1	0.8
Bone: endosteal estimation	0.4	0.9	2.0	-0.2	0.8	-0.4	-1.4	-0.7	-1.4
Bone: endosteal perimeter	0.1	0.2	0.6	-0.2	0.2	-0.1	-0.7	-0.5	-0.8
Epididymis fat weight	0.4	2.0	4.1	-0.6	1.7	-2.0	-0.7	2.0	-0.2
Delta time in closed arm before/after self-admin	0.4	0.4	1.4	-0.3	0.3	0.0	-0.9	-0.2	-1.2
Delta time in open arm before/after self-admin	2.0	2.4	4.8	-1.3	1.7	-0.5	-2.0	-0.7	-2.2
Diff in mean of infusions in LGA sessions	0.4	0.7	1.6	-0.1	-1.0	1.3	1.1	-0.3	0.6
Delay discount exponential model param	1.3	1.8	4.9	0.7	-1.1	1.9	-0.1	-2.2	-0.4
Extinction: sum of active levers before priming	0.4	0.6	1.4	1.2	-0.7	-0.2	0.7	0.8	0.7
Active lever presses in extinction session 6	0.6	0.6	2.2	0.8	-0.1	-0.8	0.3	1.5	0.4
Bone: final force	0.7	1.1	3.2	-1.8	0.7	0.4	-0.8	-1.0	-1.1
Bone: final moment	0.6	1.0	2.8	-1.7	0.6	0.4	-0.8	-1.0	-1.0
Food consumed during 24 hour testing period	0.2	0.3	0.9	0.4	0.5	-0.5	-1.0	0.1	-0.5
Glucose	1.4	2.3	4.5	-1.4	2.1	-1.0	-1.7	-0.2	-1.7
Heart weight	1.8	2.8	6.9	-2.6	2.3	-1.2	-1.3	0.6	-1.2
Delay discount hyperbolic model param	1.1	1.5	3.8	0.9	-1.1	1.7	-0.1	-1.9	-0.3
Intermittent access intake day 1-15 change	0.6	3.0	6.5	-0.6	1.9	-1.0	-2.5	-0.7	-2.6
Intermittent access intake escalation	0.5	2.8	5.7	-0.9	1.9	-0.9	-2.2	-0.8	-2.4
Intermittent access intake escalation 2	2.4	4.1	8.4	0.3	2.1	-2.0	-2.9	0.2	-2.8
Intermitt. access day 1 inactive lever presses	0.0	0.5	2.7	-1.6	0.5	-0.2	0.2	0.4	0.2
Intermitt. access day 15 inactive lever presses	0.2	0.8	1.8	-1.0	0.9	-0.4	-1.1	0.1	-1.3
Intermitt. access escalation Index	0.5	1.5	3.4	-1.2	-0.5	1.8	0.6	-1.8	0.1
Intermittent access day 1 total infusions	0.2	0.6	1.2	0.3	-0.9	0.1	1.1	1.0	0.8
Intermittent access day 15 total infusions	0.2	0.6	1.5	-0.8	0.8	-0.3	-0.8	-0.1	-1.2
Intermittent access terminal intake (last 3 days)	0.9	1.5	4.2	-0.4	1.2	-0.9	-1.6	-0.0	-2.0
Intermittent access total infusions	0.1	0.1	0.3	-0.3	0.2	-0.3	-0.3	0.2	-0.5
Intermittent access day 1 locomotion	0.7	1.3	3.6	-0.5	0.1	-0.7	1.1	1.9	1.5
Intermittent access day 15 total locomotion	0.4	1.7	3.1	-0.9	1.6	-1.1	-1.6	0.4	-1.7
Intermittent access total locomotion	0.3	0.4	1.2	-0.4	0.6	-0.8	-0.1	1.1	-0.1
Intermittent access standard deviation	0.4	1.9	4.4	-0.1	1.2	-1.2	-2.1	-0.3	-2.1
Left kidney weight	1.1	8.6	14.6	-3.6	3.8	-3.1	-2.0	2.8	-1.6
Right kidney weight	1.6	11.4	19.9	-4.5	4.4	-3.6	-1.8	3.4	-1.3
Cocaine induced anxiety	0.4	1.1	3.6	-1.0	0.8	-0.9	0.5	1.9	0.6
Post-drug Anxiety	1.0	1.1	2.3	-1.5	1.3	-0.9	-0.4	1.3	-0.4
Baseline Anxiety	0.2	0.4	1.1	-0.4	0.2	0.3	-0.7	-1.0	-0.5
Tail length	1.2	6.2	10.9	-3.3	3.2	-1.5	-2.5	0.3	-2.7
Length with tail	0.5	2.4	7.3	-2.7	2.0	-0.7	-1.0	0.3	-1.1
Length without tail	0.1	0.5	1.3	-1.1	1.1	-0.5	-0.4	0.3	-0.3
Times rat made contact with spout	0.1	0.1	0.5	-0.1	-0.1	0.2	0.7	0.1	0.5
Lifetime Intake	0.1	0.1	0.3	0.1	-0.1	-0.4	0.0	0.5	-0.1
Liver weight, left	1.2	2.1	9.3	-3.0	1.4	-0.1	-0.7	-0.2	-0.8
Liver weight, right	0.7	1.2	4.7	-2.2	1.4	-0.5	-0.1	0.4	0.1
Locomotor activity	0.3	0.4	0.8	0.9	-0.4	-0.2	0.6	0.8	0.6
Locomotor testing distance	0.2	0.5	1.1	1.1	-0.6	-0.1	0.7	0.7	0.7
Locomotor testing rearing	0.2	0.8	2.3	1.5	-1.3	0.8	0.5	-0.3	0.1
Locomotion in novel chamber	0.1	0.1	0.2	-0.4	0.1	0.1	0.2	-0.3	-0.5
Locomotion in novel chamber post-restriction	0.4	1.3	2.6	-1.6	1.3	-0.6	-1.4	-0.3	-1.2
Fecal boli incidents, locomotor time 1	0.2	0.5	1.6	1.3	-0.6	-0.6	0.2	0.5	0.4
Change in fecal boli incidents, locomotor task	1.2	1.3	2.9	-1.7	1.6	-0.6	-1.2	0.1	-0.9
Time >=10cm from walls, locomotor time 1	0.2	0.3	1.0	0.1	0.1	0.2	-0.6	-1.0	-0.3
Bouts of movement, locomotor time 1	1.7	2.2	7.9	2.8	-1.8	0.3	1.0	0.4	0.9
Total resting periods, locomotor time 1	2.0	2.3	7.2	2.7	-2.0	0.7	1.1	0.1	1.1
Rest time, locomotor task time 1	0.2	0.3	0.5	0.2	-0.7	0.7	0.4	-0.4	0.7
Distance moved, locomotor task time 1	0.1	0.3	0.6	0.1	-0.6	0.7	0.7	-0.8	0.2
Vertical activity count, locomotor time 1	0.1	0.4	1.1	-0.4	0.2	0.5	-0.3	-1.0	-0.7
Time >=10cm from walls, locomotor time 2	1.0	2.8	12.4	-3.5	2.0	-0.1	-0.3	-0.4	-0.7
Bouts of movement, locomotor time 2	0.2	0.6	2.1	-0.2	-0.2	1.1	0.3	-1.5	-0.2
Total resting periods, locomotor time 2	0.2	0.6	2.2	-0.2	-0.2	1.2	0.3	-1.5	-0.1
Rest time, locomotor task time 2	1.0	1.7	5.5	2.3	-1.8	0.4	0.5	0.2	0.8
Distance moved, locomotor task time 2	0.5	0.7	3.3	-1.8	0.6	0.2	0.4	-0.1	0.1
Vertical activity count, locomotor time 2	0.7	1.7	6.0	-2.5	1.2	0.8	-0.3	-1.3	-0.7
Light reinforcement 1	1.4	6.1	11.8	-1.4	-1.8	3.0	3.4	-1.2	3.0
Light reinforcement 2	0.8	1.7	3.1	1.2	-1.7	1.5	1.4	-0.5	1.2
Bone: marrow area	0.3	0.8	1.8	-0.3	0.8	-0.4	-1.3	-0.6	-1.3
Bone: maximum diameter	0.3	0.6	1.9	-1.4	0.7	0.2	-0.4	-0.7	-0.5
Bone: maximum force	0.6	1.1	5.0	-2.2	1.0	-0.1	-0.6	-0.2	-0.6
Bone: maximum moment	0.5	0.9	4.1	-2.0	0.9	-0.1	-0.6	-0.1	-0.6
Mean time between licks in bursts	0.1	0.8	1.8	1.3	-0.1	-1.2	-0.4	1.3	-0.2
Mean num. licks in bursts	0.2	0.5	1.2	-0.8	-0.1	0.4	1.1	0.3	0.8
Cd content in liver	0.2	0.2	0.8	-0.5	0.5	0.1	-0.2	-0.4	-0.9
Co content in liver	0.5	0.6	1.9	0.5	0.7	-1.4	-0.4	1.0	-0.2
Cu content in liver	0.7	0.8	3.1	0.4	0.4	-0.2	-1.2	-0.4	-1.8
Fe content in liver	3.1	3.8	8.7	0.5	-2.4	3.0	0.9	-2.7	0.5
K content in liver	0.7	0.7	1.7	-0.6	0.9	-0.5	-1.1	-0.1	-1.3
Mg content in liver	2.2	2.4	5.5	-0.9	1.7	-0.7	-2.0	-0.8	-2.3
Mn content in liver	0.7	0.8	2.7	-1.6	1.3	-0.5	-0.3	0.2	0.0
Na content in liver	0.2	0.2	0.4	0.6	-0.5	0.2	-0.5	-0.2	-0.4
Rb content in liver	3.2	3.7	7.1	-2.0	2.7	-1.8	-1.5	0.7	-2.3
Se content in liver	0.2	0.3	0.6	-0.6	0.3	0.3	-0.5	-0.8	-0.6
Sr content in liver	0.3	0.3	0.8	0.6	-0.1	-0.6	0.2	0.9	0.5
Zn content in liver	1.0	1.2	3.2	0.3	-0.2	0.8	-1.1	-1.4	-1.8
Bone: minimum diameter	0.6	1.2	2.6	-1.0	1.4	-1.6	-0.2	1.4	0.2
Time in familiar zone, hab. session 1	0.5	0.5	2.3	1.5	-0.9	0.1	0.0	-0.1	0.1
Time in novel zone, hab. session 1	0.8	0.9	4.3	-2.1	1.0	0.1	-0.1	-0.4	-0.2
Total zone transitions, hab. session 1	0.7	0.9	2.1	1.5	-0.7	-0.3	0.7	1.4	0.7
Total locomotion distance, hab. session 1	0.6	0.8	1.5	1.2	-0.7	-0.3	0.8	1.2	0.8
Locomotion velocity, hab. session 1	1.0	1.5	2.5	1.6	-1.1	-0.2	1.2	1.5	1.2
Time in familiar zone, hab. session 2	0.2	0.3	1.2	0.1	-0.3	0.7	0.1	-1.1	0.1
Time in novel zone, hab. session 2	0.5	0.6	1.2	-0.9	0.8	-0.9	-0.2	1.1	-0.1
Total zone transitions, hab. session 2	0.5	0.7	2.5	0.8	0.2	-0.9	-0.2	1.6	-0.1
Total locomotion distance, hab. session 2	0.1	0.1	0.4	-0.1	-0.1	0.0	0.3	0.7	0.3
Locomotion velocity, hab. session 2	0.2	0.2	0.5	0.2	-0.5	0.2	0.6	0.7	0.4
Novel to familiar place preference ratio	0.5	0.6	2.9	-1.7	0.3	0.4	0.5	-0.3	0.3
Novelty place preference	0.4	0.5	2.5	-1.6	0.4	0.3	0.5	-0.3	0.4
Time in novel zone, NPP test	0.5	0.5	2.6	-1.6	0.4	0.3	0.4	-0.4	0.3
Total zone transitions, NPP test	1.1	1.6	4.0	2.0	0.3	-1.4	-0.8	1.5	-0.7
Total locomotion distance, NPP test	1.1	1.6	3.8	1.0	0.8	-1.8	-0.7	2.0	-0.5
Locomotion velocity, NPP test	1.3	1.8	4.7	1.2	0.7	-1.9	-0.6	2.2	-0.4
Intraocular pressure	1.2	2.0	3.5	1.9	-1.7	0.6	1.5	-0.3	1.8
Delta distance traveled before/after self-admin	0.6	0.6	1.0	0.3	-1.0	1.0	0.6	-0.9	0.7
Delta ambulatory time before/after self-admin	0.8	1.4	2.3	0.4	-1.5	1.5	1.2	-0.9	1.2
Parametrial fat weight	0.3	0.7	1.5	-0.4	-0.7	0.3	1.2	0.9	1.2
Pavlov. Cond. lever latency	0.6	0.8	1.6	-0.9	0.9	-0.0	-1.0	-1.3	-0.8
Pavlov. Cond. magazine entry latency	1.5	1.9	3.5	-0.9	-1.4	1.7	1.9	-0.2	1.5
Pavlov. Cond. change in total contacts	0.1	0.1	0.4	-0.3	-0.1	0.2	-0.3	0.3	-0.6
Pavlov. Cond. index score	1.1	1.3	2.5	0.3	-1.5	1.0	1.6	0.6	1.4
Pavlov. Cond. latency score	1.2	1.6	3.2	0.3	-1.5	0.9	1.8	0.9	1.6
Pavlov. Cond. lever contacts	0.8	0.9	1.3	0.7	-1.2	0.3	1.1	1.1	1.0
Pavlov. Cond. magazine entry number	0.9	1.1	1.9	1.0	1.0	-1.2	-1.4	-0.1	-1.1
Pavlov. Cond. intertrial magazine entries	0.7	0.9	2.4	0.3	0.1	0.4	-1.1	-1.5	-1.1
Pavlov. Cond. lever-magazine prob. diff.	0.8	1.0	1.8	0.5	-1.3	0.7	1.3	0.7	1.1
Pavlov. Cond. response bias	0.5	0.7	1.5	0.1	-1.2	1.1	0.9	0.0	0.6
Pavlov. Cond. lever latency	1.5	2.0	6.4	2.5	0.0	-1.6	-1.1	1.1	-0.9
Pavlov. Cond. magazine entry latency	1.9	2.6	6.2	-1.6	-1.0	2.5	1.3	-2.0	0.7
Pavlov. Cond. change in total contacts	0.8	2.0	4.9	-1.8	-0.8	2.2	0.7	-1.7	0.2
Pavlov. Cond. index score	1.9	2.9	6.3	-2.3	-0.6	2.5	0.9	-2.1	0.4
Pavlov. Cond. latency score	1.4	2.2	4.8	-2.0	-0.4	2.2	0.7	-1.9	0.2
Pavlov. Cond. lever contacts	1.8	2.7	7.0	-2.6	-0.3	2.0	1.4	-1.4	1.1
Pavlov. Cond. magazine entry number	1.7	2.1	5.0	1.8	0.6	-2.2	-0.7	1.9	-0.2
Pavlov. Cond. intertrial magazine entries	0.6	1.2	3.1	0.5	1.2	-1.8	-0.4	1.5	0.1
Pavlov. Cond. lever-magazine prob. diff.	1.8	2.7	6.0	-2.2	-0.6	2.4	1.0	-2.1	0.4
Pavlov. Cond. response bias	2.7	3.8	8.7	-2.9	-0.5	2.6	1.3	-2.1	0.9
Time in closed arm before self-admin	1.3	2.3	3.7	1.7	-1.9	1.5	1.3	-1.2	1.2
Time in closed arm after self-admin	1.3	1.5	3.1	0.8	-1.6	1.8	0.8	-1.4	0.1
Time in open arm before self-admin	0.2	0.2	0.5	-0.5	0.3	-0.3	0.4	0.3	0.7
Time in open arm after self-admin	3.0	3.3	5.8	-1.5	2.4	-1.5	-2.3	0.2	-2.1
Bone: periosteal estimation	0.3	0.6	1.0	-1.0	1.0	-0.5	-0.9	-0.2	-0.8
Bone: periosteal perimeter	0.3	0.5	1.1	-1.0	0.9	-0.8	-0.4	0.6	-0.2
Bone: post-yield work	0.6	1.0	1.6	0.3	0.7	-1.2	-1.3	1.0	-1.3
Progressive ratio test 1 active lever presses	0.1	0.2	0.5	0.1	-0.7	0.6	0.6	0.0	0.1
Progressive ratio test 1 breakpoint	0.1	0.2	0.5	0.2	-0.7	0.5	0.6	0.1	0.1
Progressive ratio test 1 inactive lever presses	0.0	0.1	0.2	-0.1	-0.4	0.4	0.1	-0.0	-0.4
Progressive ratio test 2 active lever presses	0.2	0.2	0.7	-0.3	-0.4	0.8	0.2	-0.5	-0.0
Progressive ratio test 2 breakpoint	0.2	0.3	0.7	-0.5	-0.3	0.8	0.2	-0.6	-0.2
Progressive ratio test 2 inactive lever presses	0.1	0.2	0.4	-0.6	0.3	-0.1	-0.4	0.2	-0.7
Incentive Sensitization - Responses	0.0	0.0	0.0	-0.2	0.1	-0.0	-0.2	0.1	0.0
Incentive Sensitization - Breakpoint	0.0	0.0	0.1	-0.2	-0.0	0.2	-0.1	-0.1	0.1
Sum of active levers in priming session hrs 5-6	0.6	0.5	1.3	0.5	0.4	-0.5	-1.1	0.1	-1.1
Progressive ratio	0.1	0.2	0.6	0.2	-0.5	0.8	0.3	-0.3	-0.2
Food seeking constrained by brief footshock	0.1	0.1	0.3	-0.2	-0.1	-0.2	-0.0	0.5	0.3
Seeking ratio, punishment vs. effort	0.0	0.1	0.4	-0.1	0.0	-0.2	0.1	0.2	0.6
Retroperitoneal fat weight	0.9	4.1	19.9	-4.5	1.4	0.9	1.0	-0.2	0.9
Reaction time number correct	1.2	4.1	6.8	-1.7	2.5	-1.3	-2.6	-0.4	-2.6
Reaction time mean minus median	0.0	0.3	1.3	-1.1	0.4	0.1	0.2	-0.1	0.2
Reaction time mean minus median AUC	0.2	1.0	4.7	-2.2	1.1	-0.3	-0.2	0.1	-0.2
Reaction time num false alarms	0.0	0.0	0.1	-0.2	0.0	-0.2	-0.1	0.4	-0.2
Reaction time num false alarms AUC	0.0	0.1	0.1	-0.1	-0.3	0.3	0.0	-0.2	-0.2
Reaction time trials correct on left	1.2	4.1	6.8	-1.7	2.5	-1.3	-2.6	-0.4	-2.6
Reaction time trials on left	1.2	3.9	6.4	-1.7	2.5	-1.2	-2.5	-0.5	-2.5
Reaction time mean	0.7	1.6	3.8	0.4	-1.3	1.9	0.6	-1.9	0.3
Reaction time mean AUC	0.4	1.0	2.7	0.1	-0.9	1.5	0.5	-1.6	0.2
Median of all reaction times	1.6	2.5	4.7	1.1	-1.8	2.2	0.8	-2.2	0.4
Reaction time omissions	0.4	0.6	1.1	-1.1	-0.2	0.8	1.0	-0.4	0.8
Reaction time false alarm rate	0.7	1.0	2.1	0.6	-1.4	0.8	1.3	0.0	1.1
Reaction time premature initiation rate	2.0	3.1	5.2	0.5	-2.2	2.3	2.2	-0.9	1.7
Reaction time premature initiations	0.3	0.9	2.4	-0.4	-0.8	1.6	0.6	-1.3	0.1
Std. dev. reaction times	0.2	0.7	1.7	-1.3	-0.1	0.9	0.6	-0.9	0.6
Reaction time trials completed	1.2	3.9	6.4	-1.7	2.5	-1.2	-2.5	-0.5	-2.5
Reaction time trials AUC	1.1	3.9	6.9	-1.7	2.3	-0.8	-2.5	-0.9	-2.6
Run reversals in cocaine runway, females	1.6	1.8	3.3	0.3	1.4	-1.4	-1.8	0.8	-1.8
Run reversals in cocaine runway, males	0.1	0.1	0.4	0.6	-0.2	0.0	-0.1	-0.0	0.3
Latency to leave start box in cocaine runway	0.3	0.4	1.1	-0.3	-0.5	1.1	0.2	-1.0	0.1
Latency to leave start box in cocaine runway, F	0.1	0.2	0.4	0.6	-0.5	-0.0	0.3	0.3	0.5
Latency to leave start box in cocaine runway, M	2.1	2.0	5.2	-1.6	-0.2	2.0	-0.0	-2.3	-0.5
Std. dev. time between licks in bursts	0.5	0.9	1.9	-0.8	1.1	-1.2	0.0	1.4	0.5
Total sessions with >9 infusions	1.2	1.4	2.6	0.8	-1.1	0.0	1.6	1.3	1.5
Short access day 1 total inactive lever presses	0.7	1.3	3.5	-0.6	1.3	-1.9	-0.6	1.5	-0.2
Short access day 10 total inactive lever presses	0.3	2.1	3.5	-1.4	1.6	-1.0	-1.9	0.3	-1.8
Short access day 1 total infusions	0.5	1.0	2.7	1.1	-0.5	-0.8	0.6	1.6	0.8
Short access day 10 total infusions	0.5	0.8	1.7	0.4	-1.2	0.6	1.3	0.6	0.8
Short access total infusions	0.5	0.7	0.9	0.8	-0.9	-0.1	0.9	0.9	1.0
Short access day 1 locomotion	0.9	1.4	2.6	1.2	-1.3	0.5	1.5	0.6	1.6
Short access day 10 total locomotion	0.7	3.0	8.5	-0.2	1.6	-2.6	-0.5	2.9	0.3
Short access total locomotion	1.1	1.7	4.2	-0.1	-0.2	-0.7	1.4	2.0	1.8
One hour access (0.3 mA shock)	2.0	2.3	6.3	-0.1	0.9	-0.1	-2.3	-1.3	-2.5
Compulsive drug intake	0.8	1.2	3.4	0.1	0.8	-0.1	-1.9	-1.1	-1.4
One hour access (shock baseline)	0.1	0.3	0.6	-0.4	-0.7	0.8	0.6	-0.5	-0.1
Social response proportion	2.6	3.2	8.2	-1.3	-1.2	2.9	0.6	-2.8	-0.2
Social responses	3.6	4.7	12.2	0.1	-2.2	3.5	1.5	-3.0	0.7
Social time	0.8	1.2	4.7	-0.5	-0.5	1.5	0.2	-2.2	-0.3
Soleus weight	0.2	0.7	2.2	0.2	-0.6	1.3	0.1	-1.5	-0.1
Bone: stiffness	0.4	0.7	3.3	-1.8	0.7	0.1	-0.4	-0.1	-0.6
Tibialis anterior weight	0.5	1.7	5.4	-0.9	-0.5	1.8	-0.2	-2.3	-0.6
Time to tail flick, vehicle, before self-admin	0.3	0.3	1.4	-0.0	0.1	-0.4	0.6	0.3	1.2
Time to tail flick, vehicle, after self-admin	0.1	0.2	0.6	-0.2	0.6	-0.5	-0.8	-0.2	-0.3
Time to tail flick, test, before self-admin	0.4	0.4	0.9	0.1	-0.7	0.7	0.9	-0.5	0.6
Time to tail flick, test, after self-admin	0.2	0.2	0.7	-0.8	0.2	0.2	0.3	-0.2	0.3
Delta time to tail flick, vehicle, before/after SA	1.6	1.7	3.1	-1.3	1.4	-0.4	-1.7	-0.5	-1.8
Delta time to tail flick, test, before/after SA	0.1	0.1	0.2	-0.3	0.2	0.0	0.2	0.2	0.4
Tibia length	0.6	1.6	3.8	-1.3	0.1	-0.6	1.3	1.9	1.5
Ambulatory time before self-admin	0.2	0.5	1.1	-0.6	1.0	-0.8	-0.2	1.1	-0.2
Ambulatory time after self-admin	0.1	0.2	0.5	0.1	-0.4	0.7	0.1	-0.6	-0.1
Bone: tissue strength	0.5	0.5	1.2	-0.4	0.7	-1.1	-0.4	1.1	-0.2
Total heroin consumption	0.8	0.9	2.6	1.0	0.3	-1.3	-0.3	1.6	0.3
Bone: trabecular number	1.3	2.5	4.0	-1.7	2.0	-0.8	-1.9	-0.3	-2.0
Bone: trabecular spacing	2.4	3.5	7.5	0.9	-1.9	1.5	2.6	-0.1	2.7
Bone: trabecular thickness	0.4	0.6	1.4	0.4	-0.1	0.4	-0.9	-1.0	-1.2
Bone: trabecular tissue density	1.4	2.4	4.5	1.9	0.3	-1.2	-2.1	0.6	-2.1
Water consumed over 24 hours	0.4	0.8	1.9	0.0	-0.9	1.3	0.4	-1.4	0.4
Number of responses in last shaping day	0.8	1.1	2.2	0.7	-1.2	0.4	1.5	0.6	1.3