Hub : Genes

Bag5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	pVTA	mRNA stability	Bag5	0.08	0.09	7.9e-05	0.07	0.05	0.05	0.06	2.2e-06	4.8e-05	9.5e-05	7.7e-06
2	Liver	gene expression	Bag5	0.02	0.02	6.3e-03	0.01	0.01	0.01	0.01	1.4e-02	3.0e-02	1.2e-02	2.5e-02
3	Brain	gene expression	Bag5	0.12	0.1	1.7e-08	0.09	0.08	0.07	0.08	1.2e-08	4.2e-08	4.2e-07	5.7e-08
4	Liver	alternative TSS	XM_006240601.4	0.02	0.02	7.8e-03	0	0.01	0	0	8.8e-02	6.5e-02	3.3e-01	1.7e-01
5	Liver	alternative TSS	NM_001008526.2	0.02	0.02	1.0e-02	0	0	-0	0	1.0e-01	9.3e-02	3.8e-01	2.4e-01
6	Adipose	isoform ratio	XM_006240601.4	0.02	0.02	7.8e-03	0.01	0.01	0.01	0.01	2.5e-02	1.8e-02	2.6e-02	3.2e-02
7	Adipose	isoform ratio	NM_001008526.2	0.02	0.02	9.5e-03	0.01	0.01	0.01	0.01	3.0e-02	2.4e-02	2.7e-02	3.8e-02
8	IL	alternative polyA	NM_001008526.2	0.13	0.11	5.5e-03	0.08	0.09	0.05	0.09	6.5e-03	3.7e-03	2.4e-02	4.6e-03
9	IL	alternative polyA	XM_006240601.4	0.12	0.11	8.5e-03	0.07	0.08	0.04	0.07	9.4e-03	5.5e-03	3.6e-02	7.4e-03
10	pVTA	gene expression	Bag5	0.04	0.04	5.4e-03	0.03	0.03	0.01	0.03	1.8e-03	3.8e-03	4.7e-02	4.2e-03
11	Adipose	gene expression	Bag5	0.07	0.07	3.2e-05	0.03	0.03	0.04	0.03	3.6e-04	3.8e-04	4.0e-05	5.5e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Bone: apparent density	0.1	0.2	0.3	0.5	0.5	0.5	0.4	-0.4	-0.4	0.4	0.4	-0.4	0.5	-0.1
Area under the delay curve	0.1	0.1	0.3	0.4	0.4	0.1	0.3	-0.3	-0.3	0.3	0.3	-0.3	0.5	0.1
BMI with tail	3.7	12.7	14.4	3.4	3.3	3.6	3.8	-3.8	-3.8	3.8	3.8	-3.8	3.3	2.5
BMI without tail	2.6	8.0	9.4	2.3	2.3	2.8	3.1	-3.0	-3.1	3.1	3.0	-3.0	2.4	3.0
Body weight	0.1	0.5	1.4	-1.1	-1.1	-0.6	-0.3	0.3	0.3	-0.3	-0.3	0.3	-0.4	1.2
Weight adjusted by age	0.1	0.1	0.6	-0.2	-0.2	0.1	-0.2	0.2	0.2	-0.2	-0.2	0.2	-0.1	-0.8
Bone surface	0.1	0.2	0.4	0.5	0.5	0.5	0.4	-0.4	-0.4	0.4	0.4	-0.4	0.5	-0.6
Bone volume	0.1	0.2	0.3	0.4	0.4	0.4	0.5	-0.5	-0.5	0.5	0.5	-0.5	0.6	-0.0
Breakpoint value in progressive ratio session	0.0	0.0	0.2	0.1	-0.0	-0.1	-0.2	0.2	0.2	-0.2	-0.2	0.2	-0.1	-0.4
Number of licking bursts	0.1	0.1	0.5	-0.0	-0.0	-0.1	-0.2	0.2	0.2	-0.2	-0.2	0.3	-0.7	-0.4
Context. condit. distance diff. score	1.8	2.2	3.3	-1.8	-1.8	-1.8	-1.4	1.4	1.4	-1.4	-1.4	1.4	-1.3	0.1
Locomotion velocity, session 1	0.3	0.3	1.3	-0.4	-0.4	-0.3	-0.5	0.5	0.5	-0.5	-0.5	0.5	-0.5	-1.1
Locomotion distance, session 1	0.5	0.7	1.1	1.0	1.0	1.0	0.7	-0.7	-0.7	0.7	0.7	-0.7	0.7	-1.0
Locomotion velocity, session 2	0.1	0.1	0.4	-0.2	-0.2	-0.2	0.1	-0.1	-0.1	0.1	0.1	-0.1	0.5	0.6
Locomotion distance, session 2	0.3	0.4	0.6	0.7	0.7	0.7	0.7	-0.7	-0.7	0.7	0.7	-0.7	0.8	0.3
Locomotion velocity, session 3	0.2	0.2	0.6	0.4	0.5	0.4	0.4	-0.4	-0.4	0.4	0.5	-0.5	0.8	0.1
Locomotion distance, session 3	0.0	0.0	0.3	0.1	0.1	0.0	-0.1	0.1	0.1	-0.1	-0.1	0.1	-0.1	-0.6
Stereotopy head waving bouts, day 3	0.1	0.1	0.2	-0.4	-0.4	-0.4	-0.4	0.4	0.4	-0.4	-0.4	0.4	-0.3	-0.2
Stereotopy head waving duration, day 3	0.3	0.3	0.5	-0.7	-0.7	-0.6	-0.6	0.6	0.6	-0.6	-0.6	0.6	-0.4	-0.1
Locomotion velocity, session 7	0.3	0.3	0.6	0.7	0.7	0.6	0.5	-0.5	-0.5	0.5	0.5	-0.5	0.7	-0.2
Locomotion distance, session 7	0.7	0.9	1.1	1.0	1.1	1.0	0.9	-0.9	-0.9	0.9	0.9	-0.9	1.0	0.5
Stereotopy head waving bouts, day 7	0.5	0.6	0.7	-0.8	-0.8	-0.8	-0.8	0.8	0.8	-0.8	-0.8	0.8	-0.7	-0.6
Stereotopy head waving duration, day 7	0.3	0.3	0.4	-0.6	-0.6	-0.5	-0.6	0.6	0.6	-0.6	-0.6	0.6	-0.4	-0.4
Locomotion velocity, session 8	0.2	0.3	0.7	-0.7	-0.7	-0.9	-0.5	0.5	0.5	-0.5	-0.4	0.4	-0.2	0.3
Locomotion distance, session 8	0.1	0.1	0.5	-0.2	-0.1	-0.1	0.2	-0.2	-0.2	0.2	0.2	-0.2	0.3	0.7
Degree of sensitization distance	0.1	0.1	0.2	0.4	0.4	0.5	0.3	-0.3	-0.3	0.3	0.3	-0.3	0.3	0.0
Degree of sensitization stereotypy	0.2	0.2	0.9	-0.3	-0.3	-0.3	-0.5	0.5	0.5	-0.5	-0.5	0.5	-0.4	-0.9
Conditioned locomotion	1.1	1.2	1.7	-1.3	-1.3	-1.2	-1.2	1.2	1.2	-1.2	-1.1	1.1	-0.8	-0.3
Cocaine response after cond. corrected	0.5	0.6	0.8	0.7	0.8	0.8	0.7	-0.7	-0.7	0.7	0.7	-0.7	0.7	0.9
Cocaine response after cond. not corrected	1.8	2.1	2.2	1.4	1.4	1.5	1.5	-1.5	-1.5	1.5	1.5	-1.5	1.4	1.4
Cocaine response before conditioning	2.2	2.7	3.0	1.6	1.6	1.6	1.7	-1.7	-1.7	1.7	1.7	-1.7	1.5	1.1
Saline control response	0.1	0.1	0.2	0.3	0.3	0.2	0.4	-0.4	-0.4	0.4	0.4	-0.4	0.3	0.2
Bone: connectivity density	0.0	0.0	0.2	-0.1	-0.0	-0.2	-0.1	0.1	0.1	-0.1	-0.1	0.1	0.1	-0.4
Bone: cortical apparent density	7.7	10.5	11.8	-3.3	-3.3	-3.3	-3.4	3.4	3.4	-3.4	-3.4	3.4	-3.2	-1.5
Bone: cortical area	0.5	0.8	1.4	-1.0	-1.0	-0.9	-0.9	0.9	0.9	-0.9	-0.9	0.9	-1.2	0.1
Bone: cortical porosity	0.0	0.0	0.1	-0.4	-0.3	-0.2	-0.1	0.1	0.1	-0.1	-0.1	0.1	-0.1	0.0
Bone: cortical porosity	0.2	0.2	0.2	0.3	0.4	0.5	0.4	-0.4	-0.4	0.4	0.4	-0.4	0.4	-0.1
Bone: cortical thickness	0.6	0.9	1.3	-1.0	-0.9	-0.8	-1.0	1.0	1.0	-1.0	-1.1	1.1	-1.1	-0.3
Bone: cortical thickness	0.8	1.0	1.4	-1.2	-1.1	-1.0	-1.0	1.0	1.0	-1.0	-1.0	1.0	-1.0	0.3
Bone: cortical tissue density	7.6	10.3	11.5	-3.3	-3.3	-3.3	-3.4	3.4	3.4	-3.4	-3.4	3.4	-3.1	-1.5
Condit. Reinf. active minus inactive responses	0.6	0.7	2.0	0.7	0.7	0.8	0.8	-0.8	-0.8	0.8	0.8	-0.8	0.7	1.4
Condit. Reinf. active-inactive response ratio	2.5	2.7	3.0	1.7	1.7	1.7	1.7	-1.7	-1.7	1.7	1.7	-1.7	1.6	1.2
Condit. Reinf. active responses	0.4	0.4	3.0	0.2	0.3	0.3	0.5	-0.5	-0.5	0.5	0.5	-0.5	0.6	1.7
Condit. Reinf. inactive responses	1.7	2.0	2.3	-1.5	-1.5	-1.5	-1.5	1.5	1.5	-1.5	-1.5	1.5	-1.4	-0.3
Incentive salience index mean	0.5	0.6	0.7	0.8	0.8	0.9	0.8	-0.8	-0.8	0.8	0.8	-0.8	0.7	0.7
Condit. Reinf. lever presses	0.2	0.2	0.4	0.5	0.5	0.5	0.4	-0.4	-0.4	0.4	0.4	-0.4	0.6	-0.2
Condit. Reinf. active minus inactive responses	0.3	0.4	0.7	-0.7	-0.7	-0.8	-0.6	0.6	0.6	-0.6	-0.6	0.6	-0.4	0.0
Condit. Reinf. active-inactive response ratio	0.4	0.5	0.9	-0.8	-0.9	-1.0	-0.6	0.6	0.6	-0.6	-0.6	0.6	-0.5	0.5
Condit. Reinf. active responses	0.1	0.1	0.6	-0.0	-0.0	-0.1	0.2	-0.2	-0.2	0.2	0.2	-0.2	0.3	0.7
Condit. Reinf. inactive responses	0.7	0.9	1.0	0.8	0.9	0.9	1.0	-1.0	-1.0	1.0	1.0	-1.0	0.9	0.9
Condit. Reinf. lever presses	1.6	2.2	2.5	1.3	1.2	1.1	1.6	-1.6	-1.6	1.6	1.6	-1.6	1.6	1.4
Condit. Reinf. lever reinforcers received	0.1	0.1	0.9	-0.1	-0.1	-0.2	0.2	-0.2	-0.2	0.2	0.2	-0.2	0.3	0.9
Conditioned reinforcement - actives	0.5	0.9	1.5	-1.2	-1.2	-1.0	-0.9	0.9	0.9	-0.9	-0.9	0.9	-0.8	0.8
Conditioned reinforcement - inactives	0.2	0.2	0.5	-0.7	-0.6	-0.4	-0.4	0.4	0.4	-0.4	-0.4	0.4	-0.2	0.6
Conditioned locomotion	0.5	0.7	2.2	0.3	0.3	0.7	0.7	-0.7	-0.7	0.7	0.8	-0.8	1.2	1.5
Patch foraging indifference point 0 sec	2.8	5.2	7.6	-2.5	-2.6	-2.8	-2.3	2.3	2.3	-2.3	-2.3	2.3	-2.1	-0.0
Patch foraging indifference point AUC	1.6	2.4	2.7	-1.6	-1.6	-1.7	-1.6	1.6	1.7	-1.7	-1.6	1.6	-1.3	-0.3
Delay disc. indifference point, 0s delay	0.2	0.2	0.5	-0.2	-0.3	-0.7	-0.5	0.5	0.5	-0.5	-0.5	0.5	-0.2	-0.6
Delay disc. indifference point, 16s delay	0.1	0.1	0.2	0.1	0.1	-0.2	0.2	-0.3	-0.2	0.2	0.3	-0.3	0.3	0.4
Delay disc. indifference point, 2s delay	0.1	0.2	0.5	0.7	0.7	0.0	0.2	-0.2	-0.2	0.2	0.2	-0.2	0.3	-0.7
Delay disc. indifference point, 24s delay	0.2	0.3	0.9	0.7	0.7	0.5	0.4	-0.3	-0.4	0.4	0.3	-0.3	0.0	-0.9
Delay disc. indifference point, 4s delay	0.2	0.2	0.4	-0.4	-0.3	-0.7	-0.4	0.4	0.4	-0.4	-0.4	0.4	-0.1	-0.1
Delay disc. indifference point, 8s delay	0.2	0.2	0.4	0.3	0.3	0.3	0.5	-0.5	-0.5	0.5	0.5	-0.5	0.6	0.4
Indifference point function ln k	0.3	0.6	0.9	-1.0	-0.8	-0.8	-0.8	0.8	0.7	-0.7	-0.8	0.8	-0.8	-0.4
Indifference point function log k	0.3	0.6	0.9	-1.0	-0.8	-0.8	-0.8	0.8	0.7	-0.7	-0.8	0.8	-0.8	-0.4
Patch foraging total patch changes 0 sec	3.0	5.7	8.4	-2.7	-2.7	-2.9	-2.4	2.4	2.4	-2.4	-2.4	2.4	-2.2	0.1
Patch foraging total patch changes 12 sec	3.5	4.6	6.2	-2.2	-2.3	-2.5	-2.2	2.2	2.2	-2.2	-2.2	2.2	-2.0	-0.1
Patch foraging total patch changes 18 sec	1.1	1.7	2.7	-1.2	-1.4	-1.6	-1.4	1.4	1.4	-1.4	-1.4	1.3	-0.8	-0.5
Patch foraging total patch changes 24 sec	0.2	0.3	0.5	-0.6	-0.6	-0.7	-0.5	0.5	0.5	-0.5	-0.5	0.4	-0.3	0.7
Patch foraging total patch changes 6 sec	2.4	3.7	6.3	-2.3	-2.3	-2.5	-1.7	1.7	1.7	-1.7	-1.7	1.7	-1.7	1.9
Patch foraging time to switch 0 sec	7.4	15.2	17.6	4.2	4.2	4.2	4.1	-4.1	-4.1	4.1	4.1	-4.1	3.6	0.9
Patch foraging water rate 0 sec	13.3	28.0	35.1	-5.7	-5.7	-5.9	-5.5	5.5	5.5	-5.5	-5.5	5.5	-5.0	-1.1
Patch foraging water rate 12 sec	7.0	14.6	18.2	-4.3	-4.2	-4.2	-3.9	3.9	3.9	-3.9	-3.9	3.9	-4.1	-0.5
Patch foraging water rate 18 sec	4.2	6.5	8.0	-2.5	-2.5	-2.7	-2.7	2.7	2.7	-2.7	-2.7	2.7	-2.8	-1.1
Patch foraging water rate 24 sec	3.9	5.4	6.8	-2.5	-2.4	-2.6	-2.4	2.4	2.4	-2.4	-2.4	2.4	-2.6	-0.6
Patch foraging water rate 6 sec	4.4	6.4	8.4	-2.9	-2.9	-2.8	-2.6	2.6	2.6	-2.6	-2.6	2.6	-2.2	0.2
Seeking ratio, delayed vs. immediate footshock	0.3	0.3	2.0	-0.3	-0.3	-0.0	-0.4	0.4	0.4	-0.4	-0.4	0.5	-0.4	-1.4
Distance traveled before self-admin	0.3	0.4	0.8	0.5	0.5	0.6	0.7	-0.7	-0.7	0.7	0.7	-0.7	0.9	0.4
Distance traveled after self-admin	0.1	0.1	0.2	-0.4	-0.4	-0.4	-0.3	0.3	0.3	-0.3	-0.3	0.3	-0.4	-0.3
Extensor digitorum longus weight	5.4	21.2	27.7	-5.3	-5.2	-5.0	-4.7	4.7	4.7	-4.7	-4.7	4.7	-4.5	-1.4
Bone: elastic displacement	0.5	0.5	0.7	-0.5	-0.5	-0.6	-0.8	0.8	0.8	-0.8	-0.8	0.8	-0.8	-0.8
Bone: elastic work	0.2	0.3	0.6	-0.3	-0.3	-0.3	-0.5	0.5	0.5	-0.5	-0.5	0.5	-0.7	-0.8
Bone: endosteal estimation	0.3	0.6	0.8	0.6	0.6	0.4	0.9	-0.9	-0.9	0.9	0.9	-0.9	0.7	0.1
Bone: endosteal perimeter	0.1	0.2	1.2	-0.0	-0.1	-0.1	0.3	-0.3	-0.3	0.3	0.3	-0.3	-0.1	1.1
Epididymis fat weight	2.6	9.0	10.5	3.2	3.2	3.1	3.1	-3.1	-3.1	3.1	3.1	-3.1	2.7	1.5
Delta time in closed arm before/after self-admin	0.0	0.0	0.2	-0.1	-0.1	0.1	0.2	-0.2	-0.2	0.2	0.2	-0.2	-0.0	0.5
Delta time in open arm before/after self-admin	0.6	0.6	1.0	-0.6	-0.6	-0.7	-0.8	0.8	0.8	-0.8	-0.8	0.8	-0.6	-1.0
Diff in mean of infusions in LGA sessions	0.0	0.0	0.3	0.3	0.1	-0.0	-0.0	0.0	0.0	-0.0	-0.0	0.0	0.5	0.2
Delay discount exponential model param	0.1	0.1	0.2	-0.3	-0.4	-0.1	-0.3	0.3	0.3	-0.3	-0.3	0.3	-0.5	-0.1
Extinction: sum of active levers before priming	0.3	0.3	0.5	0.4	0.5	0.6	0.6	-0.6	-0.6	0.6	0.6	-0.6	0.5	0.7
Active lever presses in extinction session 6	1.4	1.4	1.9	-1.4	-1.3	-1.2	-1.2	1.2	1.2	-1.2	-1.2	1.2	-0.9	-0.5
Bone: final force	0.1	0.2	0.5	-0.5	-0.5	-0.6	-0.4	0.4	0.4	-0.4	-0.5	0.5	-0.7	-0.3
Bone: final moment	0.2	0.3	0.6	-0.5	-0.5	-0.5	-0.5	0.5	0.5	-0.5	-0.5	0.5	-0.8	-0.5
Food consumed during 24 hour testing period	0.1	0.1	0.2	-0.4	-0.4	-0.4	-0.3	0.3	0.3	-0.3	-0.3	0.3	-0.2	-0.0
Glucose	0.6	1.0	1.3	-0.8	-0.8	-0.9	-1.1	1.1	1.1	-1.1	-1.1	1.1	-1.0	-0.4
Heart weight	0.6	0.9	1.3	-1.1	-1.1	-0.9	-1.0	1.0	1.0	-1.0	-1.0	1.0	-0.6	0.2
Delay discount hyperbolic model param	0.1	0.1	0.2	-0.3	-0.4	-0.1	-0.2	0.2	0.2	-0.2	-0.3	0.3	-0.4	0.1
Intermittent access intake day 1-15 change	1.4	2.9	3.7	1.5	1.7	1.7	1.8	-1.8	-1.8	1.8	1.8	-1.8	1.9	1.4
Intermittent access intake escalation	1.4	2.8	3.7	1.4	1.5	1.6	1.7	-1.7	-1.7	1.7	1.7	-1.7	1.9	1.7
Intermittent access intake escalation 2	0.7	0.8	1.0	0.8	0.8	0.9	0.9	-0.9	-0.9	0.9	0.9	-0.9	1.0	0.8
Intermitt. access day 1 inactive lever presses	0.1	0.5	0.6	-0.7	-0.7	-0.7	-0.8	0.8	0.8	-0.8	-0.8	0.8	-0.7	-0.5
Intermitt. access day 15 inactive lever presses	0.8	1.6	2.3	-1.4	-1.5	-1.5	-1.3	1.3	1.3	-1.3	-1.3	1.3	-1.3	0.1
Intermitt. access escalation Index	0.3	0.5	0.7	-0.8	-0.6	-0.8	-0.7	0.7	0.7	-0.7	-0.7	0.7	-0.7	-0.2
Intermittent access day 1 total infusions	0.4	0.6	2.4	0.3	0.3	0.7	0.7	-0.7	-0.7	0.7	0.7	-0.7	0.7	1.5
Intermittent access day 15 total infusions	1.4	2.0	5.0	0.9	1.0	1.3	1.4	-1.4	-1.4	1.4	1.4	-1.4	1.5	2.2
Intermittent access terminal intake (last 3 days)	2.0	2.6	5.7	1.1	1.2	1.5	1.6	-1.6	-1.6	1.6	1.6	-1.6	1.8	2.4
Intermittent access total infusions	1.1	1.3	5.5	0.4	0.5	0.9	1.0	-1.0	-1.0	1.0	1.0	-1.0	1.1	2.3
Intermittent access day 1 locomotion	1.8	2.3	3.4	1.1	1.1	1.5	1.5	-1.5	-1.5	1.5	1.5	-1.5	1.8	1.8
Intermittent access day 15 total locomotion	0.3	0.5	2.6	0.1	0.1	0.6	0.5	-0.5	-0.5	0.5	0.5	-0.5	0.9	1.6
Intermittent access total locomotion	0.9	1.1	4.0	0.5	0.5	0.9	1.0	-1.0	-1.0	1.0	1.0	-1.0	1.2	2.0
Intermittent access standard deviation	1.8	3.6	4.4	1.5	1.6	1.9	2.0	-2.0	-2.0	2.0	2.0	-2.0	2.1	2.1
Left kidney weight	0.7	3.4	6.0	-2.4	-2.3	-2.0	-1.8	1.8	1.8	-1.8	-1.8	1.8	-1.6	-0.2
Right kidney weight	0.6	2.9	4.9	-2.2	-2.1	-1.9	-1.7	1.7	1.6	-1.6	-1.6	1.6	-1.5	0.1
Cocaine induced anxiety	2.3	3.3	3.6	-1.6	-1.7	-1.9	-1.9	1.9	1.9	-1.9	-1.9	1.9	-1.9	-1.5
Post-drug Anxiety	4.6	4.9	5.5	-2.0	-2.1	-2.3	-2.3	2.3	2.3	-2.3	-2.3	2.3	-2.2	-1.6
Baseline Anxiety	0.0	0.0	0.0	0.2	0.2	0.1	0.2	-0.2	-0.2	0.2	0.2	-0.2	0.2	0.1
Tail length	3.5	13.7	18.9	-4.3	-4.3	-4.0	-3.7	3.7	3.7	-3.7	-3.7	3.7	-3.7	-0.6
Length with tail	5.2	22.6	29.4	-5.4	-5.4	-5.1	-4.9	4.9	4.9	-4.9	-4.9	4.9	-4.4	-1.4
Length without tail	2.3	7.5	8.3	-2.8	-2.9	-2.7	-2.9	2.9	2.9	-2.9	-2.9	2.9	-2.3	-2.0
Times rat made contact with spout	0.3	0.3	0.4	-0.6	-0.6	-0.6	-0.6	0.6	0.6	-0.6	-0.6	0.6	-0.5	0.0
Lifetime Intake	0.8	1.0	6.2	0.0	0.2	0.6	0.7	-0.7	-0.7	0.7	0.7	-0.8	0.9	2.5
Liver weight, left	2.1	3.5	5.0	-2.2	-2.2	-2.1	-1.9	1.9	1.9	-1.9	-1.9	1.9	-1.9	-0.1
Liver weight, right	0.4	0.8	0.9	0.6	0.5	0.9	0.9	-0.9	-0.9	0.9	0.9	-0.9	0.9	0.9
Locomotor activity	0.1	0.1	0.2	-0.3	-0.4	-0.4	-0.4	0.4	0.4	-0.4	-0.4	0.4	-0.1	0.0
Locomotor testing distance	0.2	0.3	0.5	-0.5	-0.6	-0.7	-0.7	0.7	0.7	-0.7	-0.6	0.6	-0.3	-0.1
Locomotor testing rearing	1.2	2.3	3.8	1.6	1.6	1.4	1.5	-1.5	-1.5	1.5	1.5	-1.5	1.9	1.2
Locomotion in novel chamber	2.9	3.7	5.1	-2.3	-2.2	-1.9	-1.9	1.9	1.9	-1.9	-1.9	1.9	-2.1	-0.1
Locomotion in novel chamber post-restriction	0.0	0.0	0.1	-0.2	-0.1	0.2	0.2	-0.2	-0.2	0.2	0.2	-0.2	-0.2	0.3
Fecal boli incidents, locomotor time 1	1.6	2.3	4.1	1.9	2.0	1.4	1.5	-1.5	-1.5	1.5	1.5	-1.5	1.3	-1.2
Change in fecal boli incidents, locomotor task	1.4	1.3	9.3	-1.5	-1.5	-0.6	-0.3	0.3	0.3	-0.3	-0.3	0.3	-0.3	3.0
Time >=10cm from walls, locomotor time 1	0.4	0.5	1.2	0.1	0.3	0.5	0.7	-0.7	-0.7	0.7	0.7	-0.7	0.8	1.1
Bouts of movement, locomotor time 1	1.7	2.0	4.2	2.0	2.0	1.0	1.1	-1.1	-1.2	1.2	1.1	-1.1	0.9	-2.0
Total resting periods, locomotor time 1	1.6	1.8	3.8	1.9	2.0	1.0	1.2	-1.2	-1.2	1.2	1.2	-1.1	0.9	-1.6
Rest time, locomotor task time 1	0.2	0.2	0.9	0.1	0.0	-0.4	-0.4	0.4	0.4	-0.4	-0.4	0.4	-0.9	-0.8
Distance moved, locomotor task time 1	0.3	0.5	2.2	-0.0	0.0	0.6	0.5	-0.5	-0.5	0.5	0.5	-0.5	1.0	1.5
Vertical activity count, locomotor time 1	0.3	0.6	0.8	-0.7	-0.8	-0.8	-0.9	0.9	0.9	-0.9	-0.9	0.9	-0.4	-0.8
Time >=10cm from walls, locomotor time 2	0.3	0.5	1.5	-0.3	-0.3	-0.7	-0.7	0.7	0.7	-0.7	-0.7	0.7	-0.1	-1.2
Bouts of movement, locomotor time 2	1.4	2.3	4.1	-1.2	-1.2	-1.6	-1.5	1.5	1.5	-1.5	-1.5	1.5	-2.0	-1.4
Total resting periods, locomotor time 2	1.0	1.8	3.9	-1.1	-1.1	-1.5	-1.3	1.3	1.3	-1.3	-1.3	1.3	-2.0	-0.9
Rest time, locomotor task time 2	0.4	0.5	2.3	-0.7	-0.7	-0.5	-0.6	0.6	0.6	-0.6	-0.6	0.6	-1.5	0.5
Distance moved, locomotor task time 2	0.3	0.4	2.0	0.6	0.7	0.5	0.5	-0.5	-0.5	0.5	0.5	-0.5	1.4	-0.1
Vertical activity count, locomotor time 2	0.6	0.8	4.7	-0.0	-0.2	-0.6	-0.8	0.8	0.8	-0.8	-0.8	0.8	-0.1	-2.2
Light reinforcement 1	0.0	0.0	0.2	-0.2	-0.0	-0.2	0.1	-0.1	-0.1	0.1	0.1	-0.1	0.1	0.4
Light reinforcement 2	1.1	1.7	2.0	1.3	1.4	1.3	1.4	-1.4	-1.4	1.4	1.4	-1.3	0.9	0.9
Bone: marrow area	0.2	0.5	0.7	0.6	0.6	0.4	0.8	-0.8	-0.8	0.8	0.8	-0.8	0.6	-0.1
Bone: maximum diameter	0.0	0.1	0.4	0.0	-0.0	-0.0	0.0	0.0	-0.0	0.0	-0.0	0.0	-0.5	0.7
Bone: maximum force	0.0	0.1	0.2	-0.3	-0.3	-0.4	-0.2	0.2	0.2	-0.2	-0.2	0.2	-0.5	-0.2
Bone: maximum moment	0.0	0.1	0.2	-0.2	-0.2	-0.3	-0.2	0.2	0.2	-0.2	-0.2	0.2	-0.5	-0.4
Mean time between licks in bursts	0.5	1.2	3.6	0.6	0.6	0.6	1.1	-1.1	-1.1	1.1	1.1	-1.1	1.2	1.9
Mean num. licks in bursts	0.0	0.1	0.2	-0.3	-0.3	-0.2	-0.1	0.1	0.1	-0.1	-0.1	0.1	0.4	0.5
Cd content in liver	0.1	0.1	0.6	-0.2	-0.2	0.1	0.0	-0.0	-0.0	0.0	0.0	-0.0	-0.1	0.7
Co content in liver	1.1	1.3	1.7	-1.2	-1.3	-1.2	-1.1	1.1	1.1	-1.1	-1.1	1.1	-0.9	-1.2
Cu content in liver	0.6	0.7	0.8	0.8	0.8	0.7	0.8	-0.8	-0.8	0.8	0.8	-0.8	0.6	0.9
Fe content in liver	0.3	0.4	0.4	0.6	0.7	0.7	0.7	-0.7	-0.7	0.7	0.7	-0.7	0.4	0.5
K content in liver	0.4	0.4	0.6	-0.8	-0.8	-0.8	-0.6	0.6	0.6	-0.6	-0.6	0.6	-0.2	-0.1
Mg content in liver	0.5	0.5	1.2	-1.1	-1.1	-1.0	-0.5	0.5	0.5	-0.5	-0.5	0.5	-0.1	0.9
Mn content in liver	0.2	0.2	0.5	0.1	0.1	0.1	0.5	-0.5	-0.5	0.5	0.5	-0.5	0.7	0.6
Na content in liver	0.1	0.1	0.5	0.3	0.3	0.3	0.2	-0.2	-0.2	0.2	0.2	-0.2	0.2	0.7
Rb content in liver	0.8	0.9	1.3	-1.1	-1.1	-0.9	-1.0	1.0	1.0	-1.0	-1.0	1.0	-1.0	-0.3
Se content in liver	0.1	0.1	0.2	0.2	0.2	0.4	0.4	-0.4	-0.4	0.4	0.4	-0.4	-0.4	0.4
Sr content in liver	0.3	0.2	0.5	-0.4	-0.5	-0.4	-0.5	0.5	0.5	-0.5	-0.5	0.5	-0.7	-0.3
Zn content in liver	1.5	1.7	3.1	-1.4	-1.5	-1.4	-1.3	1.3	1.2	-1.2	-1.3	1.3	-1.8	0.1
Bone: minimum diameter	0.5	0.8	1.5	-1.2	-1.2	-1.1	-0.8	0.8	0.8	-0.8	-0.8	0.8	-0.9	0.4
Time in familiar zone, hab. session 1	0.5	0.5	1.2	0.5	0.5	0.5	0.7	-0.7	-0.7	0.7	0.7	-0.7	1.1	0.4
Time in novel zone, hab. session 1	0.1	0.1	0.2	0.4	0.5	0.5	0.3	-0.3	-0.3	0.3	0.2	-0.2	-0.1	-0.2
Total zone transitions, hab. session 1	0.5	0.8	0.9	0.8	0.8	0.9	0.9	-0.9	-0.9	0.9	0.9	-0.9	0.9	0.6
Total locomotion distance, hab. session 1	0.1	0.2	0.8	-0.5	-0.5	-0.5	-0.2	0.2	0.1	-0.1	-0.1	0.1	-0.1	0.9
Locomotion velocity, hab. session 1	0.5	0.7	1.2	-1.1	-1.1	-1.0	-0.8	0.8	0.8	-0.8	-0.8	0.8	-0.7	0.7
Time in familiar zone, hab. session 2	0.6	0.6	1.5	0.5	0.5	0.5	0.7	-0.7	-0.7	0.7	0.8	-0.8	1.2	1.0
Time in novel zone, hab. session 2	0.0	0.0	0.1	0.1	0.1	0.2	0.2	-0.1	-0.2	0.2	0.1	-0.1	-0.3	0.2
Total zone transitions, hab. session 2	0.7	0.8	1.0	1.0	1.0	0.9	1.0	-1.0	-1.0	1.0	0.9	-0.9	0.9	0.2
Total locomotion distance, hab. session 2	0.4	0.5	0.7	-0.8	-0.7	-0.9	-0.7	0.7	0.7	-0.7	-0.7	0.7	-0.8	0.1
Locomotion velocity, hab. session 2	0.6	0.8	1.0	-0.9	-0.9	-1.0	-0.9	0.9	0.9	-0.9	-0.9	0.9	-0.9	-0.1
Novel to familiar place preference ratio	0.6	0.6	1.4	1.0	1.0	1.0	0.6	-0.6	-0.6	0.6	0.6	-0.6	0.3	-1.2
Novelty place preference	0.4	0.4	1.1	0.8	0.8	0.7	0.5	-0.5	-0.5	0.5	0.5	-0.4	0.2	-1.0
Time in novel zone, NPP test	0.3	0.3	1.1	0.8	0.8	0.7	0.4	-0.4	-0.4	0.4	0.4	-0.4	0.1	-1.0
Total zone transitions, NPP test	0.1	0.2	0.5	0.4	0.4	0.4	0.4	-0.4	-0.4	0.4	0.4	-0.4	0.3	-0.7
Total locomotion distance, NPP test	0.0	0.0	0.1	-0.2	-0.1	-0.2	-0.2	0.2	0.2	-0.2	-0.2	0.2	-0.3	-0.4
Locomotion velocity, NPP test	0.1	0.1	0.1	-0.3	-0.2	-0.3	-0.2	0.2	0.2	-0.2	-0.3	0.3	-0.4	-0.3
Intraocular pressure	0.1	0.1	0.3	0.1	0.3	0.5	0.2	-0.2	-0.2	0.2	0.2	-0.2	0.4	-0.3
Delta distance traveled before/after self-admin	0.0	0.0	0.2	0.3	0.1	0.0	0.1	-0.1	-0.1	0.1	0.1	-0.1	-0.0	-0.5
Delta ambulatory time before/after self-admin	0.4	0.5	0.7	-0.6	-0.7	-0.8	-0.7	0.7	0.7	-0.7	-0.7	0.7	-0.9	-0.8
Parametrial fat weight	0.4	0.9	1.1	0.9	0.9	1.0	1.0	-1.0	-1.0	1.0	1.0	-1.0	0.9	0.5
Pavlov. Cond. lever latency	0.6	0.7	1.1	-1.1	-1.0	-1.0	-0.8	0.8	0.8	-0.8	-0.8	0.8	-0.8	0.4
Pavlov. Cond. magazine entry latency	0.6	0.8	1.2	1.1	1.1	1.0	0.8	-0.8	-0.8	0.8	0.8	-0.8	0.9	-0.9
Pavlov. Cond. change in total contacts	0.3	0.3	0.5	0.6	0.6	0.6	0.5	-0.5	-0.5	0.5	0.6	-0.6	0.7	0.0
Pavlov. Cond. index score	1.0	1.3	2.0	1.4	1.4	1.3	1.1	-1.1	-1.0	1.0	1.0	-1.0	1.0	-0.9
Pavlov. Cond. latency score	0.7	0.9	1.4	1.2	1.2	1.1	0.8	-0.8	-0.8	0.8	0.8	-0.8	0.8	-0.8
Pavlov. Cond. lever contacts	1.1	1.3	2.0	1.4	1.4	1.4	1.1	-1.1	-1.1	1.1	1.1	-1.1	1.1	-0.4
Pavlov. Cond. magazine entry number	1.0	1.2	1.6	-1.3	-1.2	-1.1	-1.1	1.1	1.1	-1.1	-1.1	1.1	-1.2	0.3
Pavlov. Cond. intertrial magazine entries	5.2	6.3	8.0	-2.8	-2.8	-2.6	-2.6	2.6	2.6	-2.6	-2.6	2.6	-2.6	-0.2
Pavlov. Cond. lever-magazine prob. diff.	0.9	1.1	1.8	1.3	1.3	1.2	0.9	-0.9	-0.9	0.9	0.9	-0.9	0.9	-1.0
Pavlov. Cond. response bias	1.6	1.9	2.4	1.6	1.5	1.5	1.4	-1.4	-1.4	1.4	1.4	-1.4	1.4	-0.2
Pavlov. Cond. lever latency	2.1	2.9	3.3	-1.4	-1.4	-1.4	-1.8	1.8	1.8	-1.8	-1.8	1.8	-1.8	-1.6
Pavlov. Cond. magazine entry latency	4.6	5.5	6.1	2.2	2.1	2.3	2.5	-2.5	-2.5	2.5	2.5	-2.5	2.2	2.1
Pavlov. Cond. change in total contacts	3.3	5.3	5.9	2.3	2.1	2.2	2.4	-2.4	-2.4	2.4	2.4	-2.4	2.4	1.8
Pavlov. Cond. index score	4.7	6.3	7.2	2.2	2.1	2.3	2.7	-2.7	-2.7	2.7	2.7	-2.7	2.5	2.3
Pavlov. Cond. latency score	4.7	6.2	7.0	2.3	2.2	2.3	2.6	-2.6	-2.6	2.6	2.7	-2.7	2.5	2.1
Pavlov. Cond. lever contacts	2.8	3.9	4.5	1.7	1.7	1.7	2.1	-2.1	-2.1	2.1	2.1	-2.1	2.0	1.8
Pavlov. Cond. magazine entry number	4.2	5.2	6.0	-1.9	-1.9	-2.0	-2.4	2.4	2.4	-2.4	-2.4	2.4	-2.4	-2.4
Pavlov. Cond. intertrial magazine entries	4.2	6.4	7.6	-2.7	-2.7	-2.8	-2.7	2.7	2.7	-2.7	-2.6	2.6	-2.1	-1.1
Pavlov. Cond. lever-magazine prob. diff.	5.3	7.0	7.9	2.3	2.2	2.3	2.8	-2.8	-2.8	2.8	2.8	-2.8	2.7	2.6
Pavlov. Cond. response bias	3.8	5.1	5.9	1.9	1.8	1.9	2.4	-2.4	-2.4	2.4	2.4	-2.4	2.3	2.3
Time in closed arm before self-admin	1.8	2.3	3.6	1.9	1.8	1.8	1.5	-1.5	-1.5	1.5	1.5	-1.5	1.2	0.6
Time in closed arm after self-admin	0.8	0.8	1.3	1.2	1.0	0.9	0.9	-0.9	-0.9	0.9	0.9	-0.9	0.6	0.4
Time in open arm before self-admin	2.4	2.6	4.8	-2.2	-2.2	-1.8	-1.6	1.5	1.5	-1.5	-1.5	1.5	-1.3	0.4
Time in open arm after self-admin	1.9	2.1	2.9	-1.7	-1.6	-1.4	-1.5	1.5	1.5	-1.5	-1.5	1.5	-1.1	-0.5
Bone: periosteal estimation	0.0	0.1	0.2	-0.3	-0.4	-0.4	-0.1	0.1	0.1	-0.1	-0.1	0.1	-0.4	0.0
Bone: periosteal perimeter	0.1	0.2	1.5	-0.3	-0.3	-0.3	0.0	-0.0	-0.1	0.0	0.0	-0.0	-0.4	1.2
Bone: post-yield work	1.1	1.6	2.0	-1.3	-1.3	-1.4	-1.2	1.2	1.2	-1.2	-1.2	1.2	-1.4	-0.8
Progressive ratio test 1 active lever presses	0.3	0.4	2.5	0.2	0.2	0.3	0.5	-0.5	-0.5	0.5	0.5	-0.5	0.8	1.6
Progressive ratio test 1 breakpoint	0.5	0.6	2.8	0.3	0.3	0.5	0.6	-0.6	-0.6	0.6	0.6	-0.6	0.9	1.7
Progressive ratio test 1 inactive lever presses	1.1	1.6	2.0	-1.4	-1.4	-1.3	-1.3	1.3	1.3	-1.3	-1.3	1.3	-1.1	-0.2
Progressive ratio test 2 active lever presses	0.3	0.3	2.0	-0.7	-0.6	-0.3	-0.3	0.3	0.3	-0.3	-0.3	0.3	-0.4	1.4
Progressive ratio test 2 breakpoint	0.3	0.3	2.1	-0.7	-0.6	-0.3	-0.3	0.3	0.3	-0.3	-0.3	0.3	-0.4	1.4
Progressive ratio test 2 inactive lever presses	0.7	1.1	1.5	-1.2	-1.2	-1.1	-1.1	1.1	1.1	-1.1	-1.0	1.0	-1.2	0.5
Incentive Sensitization - Responses	0.2	0.2	0.6	-0.6	-0.5	-0.3	-0.4	0.4	0.4	-0.4	-0.4	0.4	-0.7	0.8
Incentive Sensitization - Breakpoint	0.2	0.3	0.6	-0.8	-0.6	-0.4	-0.4	0.4	0.4	-0.4	-0.4	0.4	-0.8	0.8
Sum of active levers in priming session hrs 5-6	0.1	0.1	0.2	-0.4	-0.4	-0.4	-0.3	0.3	0.3	-0.3	-0.3	0.3	-0.2	0.2
Progressive ratio	0.3	0.5	2.4	-1.0	-1.0	-0.4	-0.4	0.4	0.4	-0.4	-0.4	0.4	-0.2	1.5
Food seeking constrained by brief footshock	1.8	2.2	3.0	-0.9	-0.9	-1.4	-1.6	1.6	1.6	-1.6	-1.6	1.6	-1.7	-1.7
Seeking ratio, punishment vs. effort	0.4	0.6	4.4	0.5	0.4	-0.3	-0.4	0.4	0.4	-0.4	-0.4	0.4	-0.6	-2.1
Retroperitoneal fat weight	0.1	0.5	0.7	0.8	0.7	0.7	0.7	-0.7	-0.7	0.7	0.7	-0.7	0.5	0.2
Reaction time number correct	2.1	4.1	4.6	-2.0	-2.0	-2.0	-2.1	2.1	2.2	-2.1	-2.1	2.1	-1.9	-1.3
Reaction time mean minus median	0.1	0.2	0.8	0.6	0.6	0.6	0.3	-0.3	-0.3	0.3	0.3	-0.3	0.2	-0.9
Reaction time mean minus median AUC	0.1	0.2	0.4	0.6	0.6	0.5	0.4	-0.4	-0.4	0.4	0.4	-0.3	0.1	-0.5
Reaction time num false alarms	0.9	1.2	1.9	-1.3	-1.4	-1.3	-1.1	1.1	1.1	-1.1	-1.1	1.1	-0.9	0.3
Reaction time num false alarms AUC	1.2	1.9	2.6	-1.5	-1.6	-1.6	-1.4	1.4	1.4	-1.4	-1.4	1.4	-1.3	0.0
Reaction time trials correct on left	2.1	4.1	4.6	-2.0	-2.0	-2.0	-2.1	2.1	2.2	-2.1	-2.1	2.1	-1.9	-1.3
Reaction time trials on left	2.2	4.1	4.6	-2.0	-2.0	-2.0	-2.1	2.1	2.1	-2.1	-2.1	2.1	-1.9	-1.4
Reaction time mean	0.7	1.1	1.3	1.1	1.1	1.1	1.1	-1.1	-1.1	1.1	1.1	-1.1	1.1	0.2
Reaction time mean AUC	0.4	0.7	0.8	0.8	0.9	0.9	0.9	-0.9	-0.9	0.9	0.9	-0.9	0.8	0.1
Median of all reaction times	0.5	0.7	0.8	0.6	0.7	0.7	0.9	-0.9	-0.9	0.9	0.9	-0.9	0.9	0.7
Reaction time omissions	0.5	0.7	3.8	-0.3	-0.4	-0.4	-0.7	0.7	0.7	-0.7	-0.7	0.7	-0.9	-1.9
Reaction time false alarm rate	0.1	0.2	0.5	-0.5	-0.6	-0.6	-0.3	0.3	0.3	-0.3	-0.3	0.3	-0.3	0.7
Reaction time premature initiation rate	1.0	1.3	2.0	-1.3	-1.4	-1.4	-1.1	1.1	1.1	-1.1	-1.1	1.1	-1.1	0.2
Reaction time premature initiations	2.1	3.7	4.8	-2.1	-2.2	-2.2	-2.0	2.0	2.0	-2.0	-2.0	2.0	-1.8	-0.5
Std. dev. reaction times	0.3	0.5	0.8	0.9	0.9	0.9	0.6	-0.6	-0.6	0.6	0.6	-0.6	0.4	-0.7
Reaction time trials completed	2.2	4.1	4.6	-2.0	-2.0	-2.0	-2.1	2.1	2.1	-2.1	-2.1	2.1	-1.9	-1.4
Reaction time trials AUC	2.3	4.4	5.0	-2.1	-2.1	-2.1	-2.2	2.2	2.2	-2.2	-2.2	2.2	-1.9	-1.3
Run reversals in cocaine runway, females	0.9	0.9	2.2	1.4	1.3	0.6	0.7	-0.7	-0.7	0.7	0.7	-0.7	0.6	-1.5
Run reversals in cocaine runway, males	1.1	1.1	2.2	-0.8	-0.8	-0.9	-1.0	1.0	1.1	-1.1	-1.1	1.1	-1.0	-1.5
Latency to leave start box in cocaine runway	0.1	0.1	0.1	0.3	0.3	0.0	0.4	-0.4	-0.3	0.3	0.4	-0.4	0.3	0.3
Latency to leave start box in cocaine runway, F	0.1	0.1	0.3	0.5	0.5	-0.1	0.2	-0.2	-0.2	0.2	0.2	-0.3	0.4	-0.2
Latency to leave start box in cocaine runway, M	0.1	0.1	0.6	-0.1	-0.1	0.1	0.3	-0.3	-0.3	0.3	0.3	-0.3	-0.1	0.8
Std. dev. time between licks in bursts	0.6	0.8	1.5	0.5	0.5	0.7	0.9	-0.9	-1.0	1.0	1.0	-0.9	1.2	1.0
Total sessions with >9 infusions	0.5	0.6	4.1	-0.0	0.1	0.4	0.6	-0.6	-0.6	0.6	0.6	-0.6	0.9	2.0
Short access day 1 total inactive lever presses	0.1	0.1	0.7	-0.3	-0.2	-0.1	-0.0	0.0	0.0	-0.0	-0.0	0.0	-0.2	0.8
Short access day 10 total inactive lever presses	0.0	0.0	0.0	-0.1	-0.1	0.0	0.1	-0.1	-0.1	0.1	0.1	-0.1	0.1	0.1
Short access day 1 total infusions	0.4	0.5	1.9	-0.9	-0.9	-0.6	-0.5	0.5	0.5	-0.5	-0.4	0.4	-0.3	1.4
Short access day 10 total infusions	1.0	1.3	4.9	0.5	0.5	0.9	1.0	-1.0	-1.0	1.0	1.0	-1.0	1.2	2.2
Short access total infusions	0.5	0.6	4.3	-0.1	0.0	0.4	0.5	-0.5	-0.5	0.5	0.5	-0.5	0.7	2.1
Short access day 1 locomotion	0.6	0.7	3.7	0.2	0.2	0.6	0.6	-0.6	-0.6	0.6	0.7	-0.7	0.9	1.9
Short access day 10 total locomotion	1.8	3.3	5.4	1.6	1.6	1.8	1.8	-1.8	-1.8	1.8	1.8	-1.8	2.3	1.6
Short access total locomotion	0.5	0.6	2.7	0.3	0.2	0.6	0.6	-0.6	-0.6	0.6	0.6	-0.6	1.1	1.7
One hour access (0.3 mA shock)	0.2	0.2	1.7	-0.5	-0.5	-0.3	-0.2	0.2	0.2	-0.2	-0.2	0.2	-0.2	1.3
Compulsive drug intake	0.0	0.1	0.6	0.1	0.1	-0.1	-0.1	0.1	0.1	-0.1	-0.1	0.1	-0.1	-0.7
One hour access (shock baseline)	0.2	0.3	3.1	-0.6	-0.4	-0.2	-0.1	0.1	0.1	-0.1	-0.1	0.1	-0.0	1.8
Social response proportion	0.4	0.5	1.3	-0.8	-0.8	-0.8	-0.5	0.5	0.5	-0.5	-0.5	0.5	-0.5	1.1
Social responses	0.0	0.0	0.3	-0.0	-0.0	-0.2	0.2	-0.2	-0.2	0.2	0.2	-0.2	0.0	0.5
Social time	0.9	1.2	2.4	-1.4	-1.3	-1.2	-1.0	1.0	1.0	-1.0	-1.0	1.0	-1.6	-0.1
Soleus weight	0.1	0.2	1.1	-0.2	-0.1	-0.1	0.4	-0.4	-0.4	0.4	0.4	-0.4	0.5	1.1
Bone: stiffness	0.8	1.3	2.0	-1.3	-1.3	-1.3	-1.1	1.2	1.1	-1.1	-1.2	1.2	-1.4	-0.3
Tibialis anterior weight	0.2	0.7	1.1	-1.1	-1.1	-1.0	-0.8	0.8	0.8	-0.8	-0.8	0.8	-0.7	0.3
Time to tail flick, vehicle, before self-admin	0.3	0.3	0.9	-0.2	-0.3	-0.4	-0.6	0.6	0.6	-0.6	-0.6	0.6	-0.7	-0.9
Time to tail flick, vehicle, after self-admin	0.4	0.6	0.7	0.8	0.8	0.8	0.7	-0.7	-0.7	0.7	0.7	-0.7	0.8	0.2
Time to tail flick, test, before self-admin	0.0	0.0	0.0	-0.0	-0.1	-0.2	-0.0	0.0	0.1	-0.1	-0.1	0.1	0.0	-0.2
Time to tail flick, test, after self-admin	0.6	0.6	1.1	-0.6	-0.7	-0.6	-0.9	0.9	0.9	-0.9	-0.9	0.9	-1.0	-0.5
Delta time to tail flick, vehicle, before/after SA	0.0	0.0	0.1	0.1	0.2	0.1	0.2	-0.2	-0.2	0.2	0.2	-0.2	0.4	0.2
Delta time to tail flick, test, before/after SA	0.4	0.4	1.1	-0.5	-0.5	-0.4	-0.6	0.6	0.6	-0.6	-0.6	0.6	-1.0	-0.6
Tibia length	0.4	1.2	2.1	-0.7	-0.8	-0.8	-1.1	1.1	1.1	-1.1	-1.2	1.2	-1.3	-1.5
Ambulatory time before self-admin	0.4	0.6	1.0	0.8	0.7	0.8	0.8	-0.8	-0.8	0.8	0.8	-0.9	1.0	0.4
Ambulatory time after self-admin	0.1	0.1	0.1	0.4	0.2	0.2	0.4	-0.4	-0.4	0.4	0.4	-0.4	0.3	-0.1
Bone: tissue strength	0.3	0.4	1.8	0.1	-0.0	-0.2	-0.5	0.5	0.5	-0.5	-0.5	0.5	-0.8	-1.3
Total heroin consumption	2.4	2.8	3.2	-1.7	-1.7	-1.7	-1.8	1.8	1.8	-1.8	-1.8	1.8	-1.5	-0.9
Bone: trabecular number	0.0	0.0	0.0	-0.0	0.0	-0.0	0.0	-0.0	-0.0	0.0	0.0	-0.0	0.2	-0.1
Bone: trabecular spacing	0.0	0.0	0.1	0.0	0.0	0.0	0.0	-0.0	-0.1	0.1	0.0	-0.0	-0.2	-0.1
Bone: trabecular thickness	0.1	0.1	0.1	0.2	0.2	0.2	0.2	-0.2	-0.2	0.2	0.2	-0.2	0.3	0.3
Bone: trabecular tissue density	0.0	0.1	0.1	-0.1	-0.1	-0.1	-0.3	0.3	0.3	-0.3	-0.3	0.3	0.1	0.3
Water consumed over 24 hours	2.4	3.2	4.0	-2.0	-1.9	-2.0	-1.8	1.8	1.8	-1.8	-1.8	1.8	-1.7	-0.2
Number of responses in last shaping day	0.1	0.2	0.2	0.3	0.3	0.5	0.4	-0.4	-0.4	0.4	0.4	-0.4	0.4	-0.1