Hub : Genes

Bag5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Liver	gene expression	Bag5	0.02	0.02	5.3e-03	0.01	0.01	0.01	0.01	1.7e-02	2.3e-02	5.0e-02	3.3e-02
2	Brain	gene expression	Bag5	0.13	0.12	1.4e-09	0.09	0.1	0.09	0.09	2.0e-08	1.1e-09	2.2e-08	1.5e-08
3	LHb	alternative TSS	XM_006240601.3	0.13	0.12	3.3e-03	0.05	0.1	0	0.04	3.0e-02	3.0e-03	3.1e-01	3.2e-02
4	Adipose	gene expression	Bag5	0.1	0.09	4.7e-08	0.05	0.05	0.05	0.05	2.4e-06	1.9e-06	1.6e-06	4.6e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4
Bone: apparent density	0.1	0.1	0.2	-0.4	0.2	-0.2	0.4
Area under the delay curve	0.1	0.1	0.2	-0.3	0.2	-0.3	-0.5
BMI with tail	2.2	7.3	8.3	-2.5	2.8	-2.9	-2.6
BMI without tail	1.3	2.8	8.3	-0.3	1.2	-1.1	-2.9
Body weight	0.3	1.1	1.9	1.4	-0.7	0.6	-1.4
Weight adjusted by age	0.1	0.1	0.4	0.1	-0.1	0.1	0.6
Bone surface	0.1	0.1	0.2	-0.4	0.3	-0.2	0.5
Bone volume	0.0	0.0	0.1	-0.2	0.3	-0.2	-0.1
Breakpoint value in progressive ratio session	0.0	0.0	0.0	-0.2	0.1	-0.1	-0.1
Number of licking bursts	0.1	0.1	0.1	-0.1	-0.2	0.3	0.4
Context. condit. distance diff. score	1.7	2.0	3.4	1.8	-1.5	1.5	0.4
Locomotion velocity, session 1	0.2	0.2	0.3	0.3	-0.4	0.5	0.5
Locomotion distance, session 1	0.4	0.5	0.8	-0.9	0.7	-0.7	0.3
Locomotion velocity, session 2	0.2	0.2	0.6	0.3	-0.1	-0.0	-0.8
Locomotion distance, session 2	0.3	0.4	0.5	-0.6	0.7	-0.6	-0.6
Locomotion velocity, session 3	0.1	0.1	0.2	-0.4	0.4	-0.4	0.0
Locomotion distance, session 3	0.1	0.1	0.4	-0.0	-0.1	0.1	0.6
Stereotopy head waving bouts, day 3	0.1	0.1	0.2	0.4	-0.4	0.4	0.2
Stereotopy head waving duration, day 3	0.2	0.3	0.5	0.7	-0.5	0.5	-0.1
Locomotion velocity, session 7	0.3	0.3	0.5	-0.7	0.4	-0.5	0.4
Locomotion distance, session 7	0.6	0.8	1.0	-1.0	1.0	-1.0	-0.4
Stereotopy head waving bouts, day 7	1.0	1.1	1.2	1.0	-1.1	1.1	1.0
Stereotopy head waving duration, day 7	0.4	0.5	0.6	0.6	-0.7	0.6	0.8
Locomotion velocity, session 8	0.2	0.3	0.5	0.7	-0.5	0.4	-0.5
Locomotion distance, session 8	0.1	0.1	0.4	0.2	0.2	-0.1	-0.7
Degree of sensitization distance	0.1	0.1	0.2	-0.5	0.3	-0.3	0.0
Degree of sensitization stereotypy	0.5	0.5	1.5	0.2	-0.5	0.5	1.2
Conditioned locomotion	1.1	1.2	1.6	1.2	-1.3	1.2	0.6
Cocaine response after cond. corrected	0.6	0.7	1.2	-0.7	0.8	-0.7	-1.1
Cocaine response after cond. not corrected	1.9	2.1	2.2	-1.4	1.4	-1.4	-1.5
Cocaine response before conditioning	2.0	2.4	3.0	-1.7	1.7	-1.7	-0.8
Saline control response	0.2	0.2	0.3	-0.4	0.5	-0.5	-0.4
Bone: connectivity density	0.1	0.2	0.5	0.1	-0.3	0.2	0.7
Bone: cortical apparent density	7.1	9.4	12.1	3.2	-3.5	3.4	1.8
Bone: cortical area	0.7	1.1	1.7	1.2	-1.1	1.3	0.2
Bone: cortical porosity	0.0	0.0	0.2	0.1	-0.0	0.0	0.4
Bone: cortical porosity	0.1	0.2	0.2	-0.4	0.5	-0.5	0.1
Bone: cortical thickness	0.7	1.2	1.7	1.0	-1.2	1.3	0.8
Bone: cortical thickness	0.6	0.7	1.0	0.9	-0.9	1.0	0.1
Bone: cortical tissue density	7.2	9.5	12.2	3.3	-3.5	3.4	1.8
Condit. Reinf. active minus inactive responses	0.5	0.6	0.7	-0.6	0.8	-0.8	-0.9
Condit. Reinf. active-inactive response ratio	2.0	2.2	2.9	-1.6	1.7	-1.7	-0.6
Condit. Reinf. active responses	0.4	0.4	1.4	-0.1	0.4	-0.4	-1.2
Condit. Reinf. inactive responses	1.5	1.8	2.7	1.6	-1.5	1.5	0.3
Incentive salience index mean	0.4	0.4	0.6	-0.7	0.8	-0.7	-0.3
Condit. Reinf. lever presses	0.1	0.1	0.2	-0.4	0.4	-0.4	0.4
Condit. Reinf. active minus inactive responses	0.4	0.5	1.0	1.0	-0.7	0.6	-0.3
Condit. Reinf. active-inactive response ratio	0.5	0.6	1.2	1.1	-0.7	0.7	-0.5
Condit. Reinf. active responses	0.2	0.3	1.1	0.4	0.0	-0.1	-1.1
Condit. Reinf. inactive responses	0.7	0.9	1.6	-0.7	0.8	-0.9	-1.3
Condit. Reinf. lever presses	1.8	2.4	4.0	-1.0	1.5	-1.5	-2.0
Condit. Reinf. lever reinforcers received	0.3	0.4	1.6	0.4	0.0	-0.1	-1.3
Conditioned reinforcement - actives	1.8	1.8	3.0	1.7	-1.5	1.5	-0.1
Conditioned reinforcement - inactives	0.3	0.4	0.6	0.8	-0.6	0.6	-0.2
Conditioned locomotion	0.8	0.9	1.7	-0.6	0.9	-0.9	-1.3
Patch foraging indifference point 0 sec	2.9	4.7	6.2	2.5	-2.5	2.3	1.0
Patch foraging indifference point AUC	2.2	2.5	3.1	1.7	-1.8	1.8	1.0
Delay disc. indifference point, 0s delay	0.1	0.1	0.1	0.4	-0.3	0.3	-0.1
Delay disc. indifference point, 16s delay	0.4	0.4	1.5	0.2	0.1	-0.2	-1.2
Delay disc. indifference point, 2s delay	0.2	0.2	0.4	-0.6	0.3	-0.2	0.5
Delay disc. indifference point, 24s delay	0.4	0.3	0.8	-0.7	0.3	-0.2	0.9
Delay disc. indifference point, 4s delay	0.1	0.1	0.2	0.3	-0.4	0.3	-0.2
Delay disc. indifference point, 8s delay	0.2	0.2	0.4	-0.3	0.4	-0.5	-0.7
Indifference point function ln k	0.4	0.6	0.7	0.8	-0.8	0.8	0.4
Indifference point function log k	0.4	0.6	0.7	0.8	-0.8	0.8	0.4
Patch foraging total patch changes 0 sec	3.2	5.2	6.9	2.6	-2.6	2.5	0.9
Patch foraging total patch changes 12 sec	3.3	4.3	5.4	2.1	-2.3	2.2	1.5
Patch foraging total patch changes 18 sec	1.5	1.9	2.4	1.3	-1.6	1.4	1.3
Patch foraging total patch changes 24 sec	0.2	0.2	0.4	0.6	-0.6	0.4	0.0
Patch foraging total patch changes 6 sec	2.0	3.0	4.7	2.2	-1.9	1.7	-0.9
Patch foraging time to switch 0 sec	9.3	14.4	19.0	-4.4	4.2	-4.2	-1.8
Patch foraging water rate 0 sec	15.7	25.1	33.1	5.8	-5.7	5.6	2.0
Patch foraging water rate 12 sec	7.9	12.1	18.8	4.3	-3.8	3.8	0.5
Patch foraging water rate 18 sec	4.3	5.7	7.0	2.5	-2.6	2.6	1.6
Patch foraging water rate 24 sec	3.3	4.6	6.4	2.5	-2.4	2.4	0.8
Patch foraging water rate 6 sec	4.0	5.9	9.0	3.0	-2.7	2.7	0.4
Seeking ratio, delayed vs. immediate footshock	0.7	0.8	2.6	0.4	-0.5	0.5	1.6
Distance traveled before self-admin	0.1	0.1	0.3	-0.1	0.1	-0.1	-0.5
Distance traveled after self-admin	0.4	0.5	0.9	1.0	-0.7	0.7	-0.1
Extensor digitorum longus weight	4.9	19.2	26.1	5.1	-4.8	4.8	2.1
Bone: elastic displacement	0.5	0.6	0.7	0.6	-0.8	0.9	0.8
Bone: elastic work	0.1	0.1	0.2	0.2	-0.3	0.4	0.1
Bone: endosteal estimation	0.2	0.5	1.0	-0.4	0.7	-0.7	-1.0
Bone: endosteal perimeter	0.3	0.5	2.0	0.3	0.2	-0.1	-1.4
Epididymis fat weight	4.0	9.2	10.7	-3.1	3.2	-3.3	-2.5
Delta time in closed arm before/after self-admin	0.1	0.1	0.4	0.0	0.2	-0.2	-0.7
Delta time in open arm before/after self-admin	0.3	0.3	0.4	0.5	-0.7	0.7	0.3
Diff in mean of infusions in LGA sessions	0.0	0.0	0.0	0.0	-0.1	0.2	0.0
Delay discount exponential model param	0.1	0.1	0.2	0.2	-0.2	0.2	0.4
Extinction: sum of active levers before priming	0.1	0.1	0.4	-0.1	0.1	-0.0	-0.6
Active lever presses in extinction session 6	1.1	1.0	1.7	1.3	-1.1	1.1	0.1
Bone: final force	0.2	0.3	0.5	0.7	-0.6	0.7	-0.0
Bone: final moment	0.2	0.4	0.6	0.7	-0.6	0.8	0.1
Food consumed during 24 hour testing period	0.1	0.1	0.3	0.6	-0.3	0.4	-0.2
Glucose	0.7	1.1	1.4	1.0	-1.2	1.2	0.8
Heart weight	0.1	0.1	0.5	0.1	0.0	-0.1	-0.7
Delay discount hyperbolic model param	0.1	0.1	0.1	0.4	-0.2	0.3	0.2
Intermittent access intake day 1-15 change	1.2	1.1	1.3	-1.0	1.1	-1.1	-0.9
Intermittent access intake escalation	1.4	1.4	1.5	-1.1	1.2	-1.2	-1.1
Intermittent access intake escalation 2	0.1	0.1	0.1	-0.3	0.4	-0.3	-0.1
Intermitt. access day 1 inactive lever presses	2.1	2.3	3.0	1.7	-1.7	1.7	0.6
Intermitt. access day 15 inactive lever presses	0.8	0.9	1.4	1.2	-1.0	1.0	-0.1
Intermitt. access escalation Index	0.2	0.2	0.3	0.5	-0.6	0.5	-0.0
Intermittent access day 1 total infusions	0.6	0.7	1.9	-0.3	0.7	-0.7	-1.4
Intermittent access day 15 total infusions	1.9	2.1	3.2	-1.1	1.4	-1.4	-1.8
Intermittent access terminal intake (last 3 days)	2.2	2.4	3.5	-1.2	1.5	-1.5	-1.9
Intermittent access total infusions	1.2	1.3	3.5	-0.5	0.9	-0.9	-1.9
Intermittent access day 1 locomotion	1.2	1.2	2.5	-0.6	1.0	-1.0	-1.6
Intermittent access day 15 total locomotion	0.7	0.8	2.4	-0.1	0.6	-0.6	-1.6
Intermittent access total locomotion	0.7	0.8	2.2	-0.3	0.7	-0.7	-1.5
Intermittent access standard deviation	3.3	3.5	3.8	-1.6	2.0	-2.0	-1.9
Left kidney weight	0.6	1.7	2.9	1.7	-1.4	1.3	-0.5
Right kidney weight	0.3	0.9	1.6	1.3	-1.0	0.9	-0.6
Cocaine induced anxiety	2.3	2.7	3.5	1.8	-1.8	1.9	0.9
Post-drug Anxiety	2.0	2.2	2.8	1.7	-1.7	1.7	0.5
Baseline Anxiety	1.3	1.3	1.7	-1.3	1.3	-1.3	-0.6
Tail length	2.8	8.4	14.6	3.8	-3.1	3.1	-0.0
Length with tail	3.6	13.2	20.7	4.5	-4.0	3.9	0.7
Length without tail	1.7	3.8	4.7	2.0	-2.2	2.0	1.5
Times rat made contact with spout	0.3	0.3	0.4	0.6	-0.6	0.6	0.4
Lifetime Intake	1.0	1.2	4.0	-0.1	0.6	-0.6	-2.0
Liver weight, left	2.5	3.9	5.3	2.3	-2.2	2.3	0.7
Liver weight, right	0.0	0.0	0.0	0.2	-0.1	0.1	0.1
Locomotor activity	0.1	0.1	0.2	0.3	-0.4	0.4	0.2
Locomotor testing distance	0.3	0.4	0.7	0.6	-0.8	0.7	0.2
Locomotor testing rearing	1.0	1.6	2.1	-1.5	1.3	-1.4	-0.8
Locomotion in novel chamber	4.3	5.3	7.7	2.8	-2.6	2.6	0.5
Locomotion in novel chamber post-restriction	0.2	0.2	0.5	0.0	0.4	-0.3	-0.7
Fecal boli incidents, locomotor time 1	2.1	2.3	4.1	-2.0	1.6	-1.4	0.8
Change in fecal boli incidents, locomotor task	3.5	3.3	9.2	1.8	-0.5	0.4	-3.0
Time >=10cm from walls, locomotor time 1	0.9	0.9	2.6	-0.3	0.7	-0.7	-1.6
Bouts of movement, locomotor time 1	2.3	2.5	4.3	-2.1	1.2	-1.1	1.7
Total resting periods, locomotor time 1	1.9	2.1	3.9	-2.0	1.2	-1.1	1.3
Rest time, locomotor task time 1	0.6	0.6	2.1	-0.0	-0.4	0.5	1.4
Distance moved, locomotor task time 1	0.5	0.5	1.6	-0.1	0.4	-0.5	-1.3
Vertical activity count, locomotor time 1	0.6	0.6	0.8	0.7	-0.9	0.8	0.6
Time >=10cm from walls, locomotor time 2	0.6	0.7	1.2	0.3	-0.8	0.8	1.1
Bouts of movement, locomotor time 2	1.6	1.7	2.2	1.2	-1.4	1.5	1.2
Total resting periods, locomotor time 2	1.1	1.2	1.6	1.1	-1.2	1.3	0.7
Rest time, locomotor task time 2	0.3	0.3	0.6	0.8	-0.6	0.6	-0.3
Distance moved, locomotor task time 2	0.2	0.3	0.6	-0.8	0.4	-0.5	0.4
Vertical activity count, locomotor time 2	1.4	1.6	5.1	0.0	-0.8	0.8	2.3
Light reinforcement 1	0.0	0.1	0.2	0.0	0.0	-0.1	-0.5
Light reinforcement 2	1.6	2.1	2.4	-1.4	1.6	-1.4	-1.4
Bone: marrow area	0.2	0.4	0.7	-0.3	0.7	-0.6	-0.8
Bone: maximum diameter	0.0	0.1	0.1	0.2	-0.2	0.3	-0.3
Bone: maximum force	0.2	0.4	0.6	0.7	-0.6	0.7	0.0
Bone: maximum moment	0.2	0.3	0.5	0.6	-0.6	0.7	0.1
Mean time between licks in bursts	1.3	1.9	4.3	-0.7	1.2	-1.2	-2.1
Mean num. licks in bursts	0.1	0.1	0.2	0.4	-0.1	0.1	-0.2
Cd content in liver	0.4	0.5	1.0	1.0	-0.6	0.6	-0.3
Co content in liver	0.7	0.9	1.5	1.2	-1.0	1.0	-0.2
Cu content in liver	1.2	1.4	1.9	-1.1	1.1	-1.1	-1.4
Fe content in liver	0.2	0.2	0.5	-0.7	0.4	-0.3	0.4
K content in liver	0.1	0.1	0.1	0.4	-0.4	0.3	0.2
Mg content in liver	0.4	0.4	0.8	0.7	-0.3	0.3	-0.9
Mn content in liver	0.2	0.2	0.5	0.6	-0.2	0.1	-0.7
Na content in liver	0.1	0.1	0.3	-0.5	0.1	-0.1	0.5
Rb content in liver	0.6	0.8	1.2	1.1	-1.0	0.9	0.3
Se content in liver	0.1	0.1	0.2	-0.3	0.4	-0.3	0.0
Sr content in liver	0.2	0.2	0.4	0.6	-0.4	0.5	-0.2
Zn content in liver	0.2	0.2	0.4	0.6	-0.4	0.5	-0.3
Bone: minimum diameter	0.6	1.2	2.1	1.5	-1.1	1.1	-0.4
Time in familiar zone, hab. session 1	0.3	0.3	0.5	-0.6	0.6	-0.7	-0.2
Time in novel zone, hab. session 1	0.1	0.1	0.2	-0.4	0.4	-0.2	0.0
Total zone transitions, hab. session 1	0.5	0.7	0.9	-0.8	0.9	-0.9	-0.7
Total locomotion distance, hab. session 1	0.1	0.2	0.4	0.5	-0.2	0.2	-0.7
Locomotion velocity, hab. session 1	0.5	0.7	1.2	1.1	-0.8	0.8	-0.4
Time in familiar zone, hab. session 2	0.5	0.5	0.6	-0.7	0.6	-0.8	-0.7
Time in novel zone, hab. session 2	0.1	0.1	0.1	-0.0	0.2	-0.1	-0.4
Total zone transitions, hab. session 2	0.6	0.8	1.1	-1.0	1.0	-0.9	-0.4
Total locomotion distance, hab. session 2	0.3	0.4	0.5	0.7	-0.7	0.7	0.3
Locomotion velocity, hab. session 2	0.4	0.6	0.8	0.9	-0.8	0.9	0.3
Novel to familiar place preference ratio	0.5	0.5	0.8	-0.9	0.6	-0.6	0.8
Novelty place preference	0.3	0.3	0.5	-0.7	0.5	-0.5	0.6
Time in novel zone, NPP test	0.3	0.3	0.5	-0.6	0.4	-0.4	0.7
Total zone transitions, NPP test	0.1	0.1	0.2	-0.3	0.5	-0.4	0.0
Total locomotion distance, NPP test	0.0	0.1	0.1	0.2	-0.1	0.2	0.3
Locomotion velocity, NPP test	0.0	0.1	0.1	0.4	-0.2	0.3	0.1
Intraocular pressure	0.1	0.2	0.4	-0.5	0.3	-0.3	0.6
Delta distance traveled before/after self-admin	0.0	0.0	0.1	0.3	-0.1	0.1	0.2
Delta ambulatory time before/after self-admin	0.5	0.5	0.8	0.9	-0.7	0.7	0.5
Parametrial fat weight	0.0	0.0	0.1	-0.0	0.1	-0.0	0.3
Pavlov. Cond. lever latency	0.5	0.7	0.9	0.9	-0.9	0.9	-0.2
Pavlov. Cond. magazine entry latency	0.8	1.0	1.5	-1.2	0.8	-0.8	1.2
Pavlov. Cond. change in total contacts	0.2	0.2	0.3	-0.6	0.5	-0.5	0.2
Pavlov. Cond. index score	0.9	1.2	1.9	-1.4	1.1	-1.1	0.7
Pavlov. Cond. latency score	0.7	0.8	1.3	-1.1	0.9	-0.9	0.7
Pavlov. Cond. lever contacts	0.8	0.9	1.4	-1.2	1.0	-1.0	0.3
Pavlov. Cond. magazine entry number	0.9	1.1	1.5	1.2	-1.2	1.2	-0.1
Pavlov. Cond. intertrial magazine entries	4.5	5.5	8.4	2.9	-2.6	2.6	0.3
Pavlov. Cond. lever-magazine prob. diff.	0.8	1.0	1.5	-1.2	1.0	-0.9	0.8
Pavlov. Cond. response bias	1.0	1.2	1.6	-1.3	1.2	-1.2	0.1
Pavlov. Cond. lever latency	2.3	3.1	4.6	1.3	-1.8	1.8	2.1
Pavlov. Cond. magazine entry latency	4.7	5.4	6.0	-2.1	2.4	-2.5	-2.3
Pavlov. Cond. change in total contacts	3.7	5.1	5.9	-2.1	2.4	-2.4	-2.1
Pavlov. Cond. index score	5.0	6.4	7.7	-2.1	2.6	-2.6	-2.8
Pavlov. Cond. latency score	4.8	5.9	6.5	-2.1	2.5	-2.6	-2.5
Pavlov. Cond. lever contacts	3.4	4.6	7.0	-1.6	2.1	-2.1	-2.6
Pavlov. Cond. magazine entry number	4.1	5.0	6.7	1.8	-2.2	2.3	2.6
Pavlov. Cond. intertrial magazine entries	4.7	6.1	7.6	2.7	-2.8	2.7	1.6
Pavlov. Cond. lever-magazine prob. diff.	5.6	7.2	9.0	-2.2	2.7	-2.8	-3.0
Pavlov. Cond. response bias	4.4	5.9	9.0	-1.8	2.4	-2.4	-3.0
Time in closed arm before self-admin	2.6	2.9	4.2	-2.1	1.9	-1.9	-0.4
Time in closed arm after self-admin	1.3	1.3	1.8	-1.3	1.3	-1.3	-0.3
Time in open arm before self-admin	4.7	5.1	8.8	3.0	-2.4	2.4	0.1
Time in open arm after self-admin	2.7	3.0	4.7	2.2	-1.9	1.9	-0.1
Bone: periosteal estimation	0.1	0.2	0.3	0.6	-0.3	0.4	-0.5
Bone: periosteal perimeter	0.3	0.5	1.4	0.5	-0.1	0.3	-1.2
Bone: post-yield work	1.0	1.4	1.6	1.2	-1.3	1.3	1.0
Progressive ratio test 1 active lever presses	0.1	0.1	0.5	0.1	0.1	-0.1	-0.7
Progressive ratio test 1 breakpoint	0.2	0.2	0.7	-0.0	0.3	-0.3	-0.8
Progressive ratio test 1 inactive lever presses	2.2	2.4	3.1	1.7	-1.8	1.8	0.8
Progressive ratio test 2 active lever presses	0.3	0.4	1.4	0.2	0.1	-0.1	-1.2
Progressive ratio test 2 breakpoint	0.4	0.5	1.7	0.3	0.0	-0.1	-1.3
Progressive ratio test 2 inactive lever presses	0.8	0.9	1.4	1.2	-1.0	1.0	-0.2
Incentive Sensitization - Responses	0.2	0.2	0.6	0.0	0.1	-0.1	-0.8
Incentive Sensitization - Breakpoint	0.1	0.1	0.5	0.2	-0.0	0.0	-0.7
Sum of active levers in priming session hrs 5-6	0.4	0.4	1.3	-0.3	0.4	-0.4	-1.1
Progressive ratio	0.7	0.8	1.6	1.2	-0.7	0.7	-0.9
Food seeking constrained by brief footshock	1.6	2.0	2.9	0.9	-1.4	1.5	1.7
Seeking ratio, punishment vs. effort	0.6	0.7	2.4	-0.4	-0.3	0.3	1.5
Retroperitoneal fat weight	0.2	0.6	0.8	-0.9	0.9	-0.8	-0.5
Reaction time number correct	2.5	3.6	4.9	2.0	-2.2	2.1	1.0
Reaction time mean minus median	0.4	0.5	1.1	-0.8	0.5	-0.4	1.0
Reaction time mean minus median AUC	0.3	0.3	0.5	-0.7	0.5	-0.4	0.7
Reaction time num false alarms	0.8	1.1	1.7	1.3	-1.2	1.1	-0.4
Reaction time num false alarms AUC	1.2	1.6	2.4	1.5	-1.5	1.4	-0.1
Reaction time trials correct on left	2.5	3.6	4.9	2.0	-2.2	2.1	1.0
Reaction time trials on left	2.5	3.6	4.8	2.0	-2.2	2.1	1.1
Reaction time mean	0.8	1.2	1.8	-1.3	1.2	-1.2	0.1
Reaction time mean AUC	0.6	0.8	1.2	-1.1	1.0	-1.0	0.1
Median of all reaction times	0.5	0.6	0.9	-0.9	0.9	-0.9	-0.3
Reaction time omissions	1.4	2.0	5.3	0.7	-1.0	1.1	2.3
Reaction time false alarm rate	0.2	0.2	0.5	0.5	-0.4	0.3	-0.7
Reaction time premature initiation rate	0.7	0.9	1.6	1.3	-1.0	1.0	0.1
Reaction time premature initiations	2.1	3.0	4.3	2.1	-1.9	1.9	0.6
Std. dev. reaction times	0.5	0.8	1.1	-1.1	0.9	-0.8	0.8
Reaction time trials completed	2.5	3.6	4.8	2.0	-2.2	2.1	1.1
Reaction time trials AUC	2.7	3.8	5.2	2.1	-2.3	2.2	1.0
Run reversals in cocaine runway, females	1.4	1.4	2.6	-1.6	1.0	-1.1	0.8
Run reversals in cocaine runway, males	0.8	0.8	0.9	0.7	-1.0	1.0	0.9
Latency to leave start box in cocaine runway	0.2	0.2	0.6	-0.2	0.2	-0.3	-0.8
Latency to leave start box in cocaine runway, F	0.1	0.1	0.3	-0.5	0.2	-0.3	-0.3
Latency to leave start box in cocaine runway, M	0.1	0.1	0.2	-0.0	0.3	-0.3	-0.5
Std. dev. time between licks in bursts	0.9	1.0	2.1	-0.5	1.0	-0.9	-1.5
Total sessions with >9 infusions	0.5	0.6	2.1	0.3	0.2	-0.2	-1.4
Short access day 1 total inactive lever presses	0.2	0.2	0.9	0.2	0.2	-0.2	-0.9
Short access day 10 total inactive lever presses	0.3	0.3	0.4	0.6	-0.7	0.7	0.4
Short access day 1 total infusions	0.6	0.6	1.0	1.0	-0.5	0.5	-1.0
Short access day 10 total infusions	1.1	1.2	4.0	-0.1	0.6	-0.7	-2.0
Short access total infusions	1.0	1.1	4.0	0.1	0.5	-0.5	-2.0
Short access day 1 locomotion	1.1	1.2	3.5	-0.3	0.8	-0.9	-1.9
Short access day 10 total locomotion	0.8	0.9	1.9	-0.6	0.8	-0.8	-1.4
Short access total locomotion	0.5	0.5	1.9	0.1	0.2	-0.3	-1.4
One hour access (0.3 mA shock)	0.5	0.6	1.8	0.7	-0.3	0.3	-1.3
Compulsive drug intake	0.2	0.2	0.5	-0.4	0.1	-0.1	0.7
One hour access (shock baseline)	0.5	0.6	2.4	0.2	0.1	-0.1	-1.6
Social response proportion	0.5	0.6	0.8	0.9	-0.6	0.5	-0.9
Social responses	0.1	0.1	0.4	-0.0	0.2	-0.2	-0.6
Social time	0.7	1.0	1.8	1.3	-1.0	1.0	0.3
Soleus weight	0.0	0.1	0.3	0.1	0.1	-0.2	-0.5
Bone: stiffness	1.3	2.0	2.8	1.7	-1.5	1.6	0.5
Tibialis anterior weight	0.3	0.9	1.4	1.2	-1.0	1.0	0.1
Time to tail flick, vehicle, before self-admin	0.7	0.7	1.1	0.7	-0.7	0.8	1.0
Time to tail flick, vehicle, after self-admin	0.2	0.2	0.2	-0.4	0.4	-0.4	0.4
Time to tail flick, test, before self-admin	0.1	0.1	0.1	0.4	-0.3	0.3	-0.2
Time to tail flick, test, after self-admin	1.9	2.0	2.9	1.2	-1.3	1.3	1.7
Delta time to tail flick, vehicle, before/after SA	0.0	0.0	0.1	-0.3	0.2	-0.3	-0.0
Delta time to tail flick, test, before/after SA	1.2	1.1	1.8	0.9	-0.9	0.9	1.4
Tibia length	0.3	0.9	1.2	0.7	-1.0	1.1	1.0
Ambulatory time before self-admin	0.1	0.1	0.1	-0.4	0.2	-0.2	-0.3
Ambulatory time after self-admin	0.0	0.0	0.2	0.1	0.1	-0.1	-0.4
Bone: tissue strength	0.3	0.3	1.0	-0.1	-0.2	0.3	1.0
Total heroin consumption	0.8	1.0	1.4	1.1	-1.1	1.2	0.4
Bone: trabecular number	0.1	0.1	0.2	0.2	-0.3	0.2	0.4
Bone: trabecular spacing	0.1	0.2	0.4	-0.1	0.3	-0.2	-0.7
Bone: trabecular thickness	0.1	0.1	0.1	0.2	-0.3	0.4	0.3
Bone: trabecular tissue density	0.2	0.3	0.4	0.3	-0.7	0.6	0.5
Water consumed over 24 hours	2.7	3.2	4.7	2.2	-2.0	2.0	0.7
Number of responses in last shaping day	0.4	0.4	0.6	-0.5	0.8	-0.7	-0.6