Babam2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL mRNA stability Babam2 0.09 0.07 1.0e-11 0.11 0.11 0.11 0.1 9.8e-12 1.1e-11 8.5e-12 1.5e-11
2 Liver isoform ratio NM_199270.2 0.18 0.14 4.4e-16 0.14 0.14 0.14 0.14 1.1e-15 1.3e-15 1.4e-15 1.2e-15
3 Liver isoform ratio XM_006239802.4 0.39 0.35 0.0e+00 0.23 0.23 0.23 0.23 1.1e-24 4.2e-25 7.8e-25 8.8e-25
4 Liver alternative TSS NM_199270.2 0.06 0.06 1.3e-05 0.04 0.04 0.04 0.04 1.3e-05 1.4e-05 1.2e-05 1.6e-05
5 Liver alternative TSS XM_039112467.1 0.38 0.23 0.0e+00 0.29 0.3 0.3 0.3 8.1e-33 1.3e-33 2.4e-33 2.6e-33
6 LHb mRNA stability Babam2 0.31 0.2 6.8e-06 0.19 0.2 0.19 0.2 3.1e-05 1.5e-05 2.3e-05 1.8e-05
7 Brain mRNA stability Babam2 0.07 0.05 4.2e-08 0.07 0.07 0.07 0.07 3.8e-07 2.3e-07 3.5e-07 7.5e-07
8 pVTA mRNA stability Babam2 0.68 0.07 1.1e-14 0.32 0.32 0.3 0.32 3.2e-14 1.9e-14 1.4e-13 1.3e-14
9 Adipose isoform ratio XM_006239802.4 0.12 0.1 1.8e-10 0.09 0.09 0.09 0.09 8.4e-10 2.5e-10 3.2e-10 3.9e-10
10 Adipose intron excision ratio chr6_24743562_24743863 0.18 0.14 6.7e-16 0.14 0.14 0.14 0.14 3.9e-15 1.7e-15 3.8e-15 3.7e-15
11 Brain gene expression Babam2 0.05 0.04 3.7e-06 0.05 0.05 0.05 0.05 2.8e-05 1.6e-05 3.2e-05 4.3e-05
12 Adipose intron excision ratio chr6_24743562_24747293 0.33 0.26 0.0e+00 0.22 0.22 0.22 0.22 6.8e-24 2.1e-24 1.9e-24 4.4e-24
13 Adipose isoform ratio XR_005505534.1 0.03 0.03 3.9e-03 0.02 0.02 0.02 0.02 3.4e-03 3.7e-03 2.9e-03 3.8e-03
14 Liver intron excision ratio chr6_24656998_24709868 0.64 0.23 0.0e+00 0.47 0.48 0.48 0.47 4.2e-58 1.5e-59 4.5e-60 4.6e-59
15 Liver intron excision ratio chr6_24656998_24714770 0.63 0.23 0.0e+00 0.46 0.47 0.47 0.47 4.5e-57 2.3e-58 8.0e-59 7.4e-58
16 pVTA gene expression Babam2 0.07 0.06 1.9e-03 0.06 0.06 0.05 0.05 1.2e-03 1.0e-03 2.4e-03 2.5e-03
17 PL gene expression Babam2 0.07 0.05 2.1e-07 0.06 0.06 0.07 0.07 5.4e-07 1.8e-07 3.2e-08 4.1e-08
18 BLA mRNA stability Babam2 0.22 0.15 5.3e-09 0.14 0.16 0.15 0.14 4.2e-08 5.6e-09 3.0e-08 7.6e-08
19 Liver intron excision ratio chr6_24743562_24747293 0.36 0.26 0.0e+00 0.26 0.26 0.26 0.25 3.3e-28 3.0e-28 2.0e-28 4.6e-28
20 Liver intron excision ratio chr6_24743562_24743863 0.29 0.22 0.0e+00 0.2 0.21 0.21 0.2 4.2e-22 1.2e-22 7.5e-23 2.4e-22
21 Liver mRNA stability Babam2 0.38 0.22 0.0e+00 0.33 0.33 0.33 0.33 1.9e-37 1.1e-37 1.7e-37 1.0e-37
22 Liver intron excision ratio chr6_24743936_24747293 0.24 0.17 0.0e+00 0.2 0.19 0.2 0.2 2.9e-21 4.3e-21 2.5e-21 3.4e-21
23 Liver isoform ratio XM_039112467.1 0.61 0.36 0.0e+00 0.21 0.22 0.22 0.21 9.5e-23 1.3e-23 6.2e-24 3.3e-23
24 NAcc mRNA stability Babam2 0.15 0.06 0.0e+00 0.19 0.19 0.18 0.19 3.5e-21 8.7e-22 7.8e-21 3.3e-21
25 NAcc gene expression Babam2 0.09 0.09 3.5e-05 0.03 0.04 0.04 0.04 8.1e-05 1.4e-05 2.8e-05 5.5e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25
Bone: apparent density5.59.19.5-3.13.03.13.03.13.13.13.03.13.03.03.03.0-3.03.03.0-3.03.03.0-3.03.0-3.0-3.02.92.9
Area under the delay curve0.60.62.2-0.5-0.10.4-0.10.50.50.61.00.60.60.60.70.9-0.60.60.8-1.20.90.7-0.71.0-0.9-0.81.21.5
BMI with tail0.41.31.51.0-0.9-1.1-0.7-1.1-1.1-1.1-1.2-1.1-1.1-1.1-1.2-1.01.1-1.1-1.21.1-1.2-1.11.1-1.21.21.1-1.2-1.2
BMI without tail0.30.71.20.7-0.5-0.8-0.2-0.8-0.7-0.8-1.0-0.8-0.8-0.8-0.8-0.70.8-0.8-0.81.1-0.9-0.80.8-0.90.90.8-1.0-1.0
Body weight1.97.88.62.8-2.7-2.9-2.6-2.9-2.8-2.8-2.8-2.8-2.8-2.8-2.9-2.72.8-2.8-2.82.9-2.8-2.82.8-2.82.82.8-2.8-2.7
Weight adjusted by age0.00.10.30.0-0.10.00.4-0.1-0.1-0.2-0.3-0.2-0.2-0.2-0.20.10.1-0.1-0.30.3-0.3-0.10.1-0.40.20.2-0.4-0.5
Bone surface2.64.65.4-2.12.32.22.22.22.22.22.12.22.22.22.22.1-2.22.22.1-2.02.12.1-2.12.2-2.1-2.12.01.9
Bone volume2.84.75.5-2.12.32.32.22.22.22.22.22.22.22.22.22.1-2.22.22.2-2.02.22.2-2.12.2-2.1-2.12.02.0
Breakpoint value in progressive ratio session1.21.32.0-1.41.01.11.21.11.11.11.11.11.11.11.11.3-1.21.21.1-1.31.11.2-1.21.0-1.2-1.31.21.1
Number of licking bursts0.20.30.7-0.70.20.40.30.40.40.40.60.40.40.40.50.6-0.50.50.5-0.80.50.5-0.50.5-0.5-0.60.70.7
Context. condit. distance diff. score0.00.00.10.3-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.10.1-0.1-0.10.2-0.1-0.10.1-0.10.10.1-0.1-0.1
Locomotion velocity, session 10.10.10.30.20.0-0.1-0.1-0.2-0.2-0.2-0.4-0.2-0.2-0.2-0.2-0.40.2-0.2-0.30.4-0.3-0.30.3-0.40.30.3-0.4-0.5
Locomotion distance, session 12.12.62.8-1.71.71.71.61.71.71.61.61.61.61.61.71.5-1.61.61.6-1.61.61.6-1.61.5-1.6-1.61.61.5
Locomotion velocity, session 20.10.20.20.5-0.5-0.4-0.5-0.4-0.4-0.4-0.4-0.4-0.4-0.4-0.4-0.40.4-0.4-0.40.3-0.4-0.40.4-0.40.40.4-0.3-0.3
Locomotion distance, session 20.00.00.10.10.10.00.10.00.00.0-0.1-0.0-0.0-0.0-0.0-0.10.0-0.0-0.00.2-0.1-0.10.1-0.10.10.1-0.2-0.2
Locomotion velocity, session 30.50.50.7-0.70.90.80.80.80.80.80.70.80.80.70.70.7-0.80.80.7-0.60.70.7-0.70.7-0.7-0.70.60.6
Locomotion distance, session 30.91.01.1-1.01.11.01.11.01.01.01.01.01.01.01.01.0-1.01.01.0-0.91.01.0-1.01.0-1.0-1.00.90.9
Stereotopy head waving bouts, day 31.61.92.4-1.41.51.41.61.41.41.41.41.41.41.41.41.4-1.41.41.4-1.21.31.4-1.41.4-1.3-1.41.31.2
Stereotopy head waving duration, day 30.10.10.1-0.30.30.30.40.30.30.30.30.30.30.30.30.3-0.30.30.3-0.20.30.3-0.30.3-0.3-0.30.20.2
Locomotion velocity, session 70.70.81.4-0.91.21.01.11.01.01.00.81.01.01.00.90.8-0.90.90.9-0.60.90.9-0.90.8-0.8-0.80.70.6
Locomotion distance, session 70.00.00.20.20.40.10.30.10.10.1-0.10.10.10.10.0-0.0-0.10.00.00.40.0-0.00.0-0.00.10.1-0.2-0.2
Stereotopy head waving bouts, day 70.00.00.0-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.00.1-0.1-0.1-0.1-0.1-0.10.0-0.10.00.0-0.0-0.0
Stereotopy head waving duration, day 70.30.40.7-0.80.60.60.60.60.60.60.60.60.60.60.60.6-0.60.60.6-0.80.60.6-0.60.6-0.6-0.60.70.6
Locomotion velocity, session 80.00.00.3-0.20.50.30.40.30.30.2-0.00.20.20.20.20.0-0.20.20.10.20.10.1-0.10.0-0.0-0.0-0.2-0.3
Locomotion distance, session 80.20.40.6-0.30.80.60.80.70.70.70.60.70.70.60.60.6-0.60.60.6-0.20.60.6-0.60.6-0.6-0.60.50.5
Degree of sensitization distance1.01.01.41.1-0.9-1.0-0.9-1.0-1.0-1.0-1.0-1.0-1.0-1.0-1.0-1.01.0-1.0-1.01.2-1.0-1.01.0-1.01.01.0-1.0-1.0
Degree of sensitization stereotypy0.10.10.20.1-0.5-0.3-0.5-0.4-0.4-0.3-0.3-0.3-0.3-0.3-0.3-0.30.3-0.3-0.3-0.0-0.3-0.30.3-0.30.30.2-0.2-0.1
Conditioned locomotion3.44.04.4-1.91.91.91.92.02.02.02.12.02.02.02.02.1-2.02.02.0-1.92.02.0-2.02.1-2.0-2.02.02.1
Cocaine response after cond. corrected1.41.52.1-1.01.01.20.91.21.21.21.31.21.21.21.21.3-1.21.21.3-1.41.31.3-1.31.3-1.3-1.31.41.4
Cocaine response after cond. not corrected2.73.03.7-1.61.41.71.41.71.71.71.81.71.71.71.71.8-1.71.71.7-1.91.81.7-1.81.8-1.8-1.81.91.9
Cocaine response before conditioning1.01.22.0-1.41.21.21.31.11.11.11.01.11.11.11.11.1-1.11.11.1-1.11.01.1-1.11.0-1.0-1.11.00.9
Saline control response0.50.71.1-0.81.00.91.00.90.90.90.80.90.90.90.90.8-0.90.90.8-0.60.80.8-0.80.8-0.8-0.80.70.6
Bone: connectivity density5.48.59.0-3.02.93.02.92.92.92.93.02.92.92.92.92.9-2.92.92.9-3.02.92.9-2.92.9-2.9-2.92.92.8
Bone: cortical apparent density0.40.60.8-0.80.60.70.50.70.70.80.80.80.80.80.80.8-0.70.70.8-0.90.80.7-0.70.8-0.8-0.80.80.9
Bone: cortical area0.30.50.6-0.60.70.70.60.70.70.70.70.70.70.70.70.6-0.70.70.7-0.60.70.7-0.70.7-0.7-0.60.60.6
Bone: cortical porosity1.11.21.5-1.21.21.11.21.21.21.21.11.21.21.21.11.1-1.11.11.1-1.01.11.1-1.11.2-1.1-1.11.01.0
Bone: cortical porosity1.01.11.4-1.11.21.01.11.11.11.11.01.11.11.11.01.0-1.01.01.0-0.91.01.0-1.01.1-1.0-1.00.90.9
Bone: cortical thickness0.00.00.00.2-0.1-0.1-0.2-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.20.1-0.1-0.10.2-0.1-0.10.1-0.10.10.1-0.1-0.1
Bone: cortical thickness1.61.82.1-1.51.41.41.41.41.41.41.41.41.41.41.31.4-1.41.41.4-1.21.31.3-1.31.4-1.4-1.31.31.3
Bone: cortical tissue density0.30.40.6-0.70.50.60.40.60.60.60.70.60.60.60.70.6-0.60.60.7-0.70.70.6-0.60.7-0.7-0.60.70.8
Condit. Reinf. active minus inactive responses0.40.40.80.7-0.9-0.7-0.8-0.7-0.7-0.7-0.6-0.7-0.7-0.7-0.7-0.60.7-0.7-0.70.4-0.6-0.60.6-0.60.60.6-0.5-0.5
Condit. Reinf. active-inactive response ratio0.50.51.00.8-1.0-0.8-0.9-0.8-0.8-0.8-0.6-0.8-0.8-0.8-0.7-0.60.7-0.7-0.70.4-0.7-0.70.7-0.70.60.6-0.5-0.5
Condit. Reinf. active responses0.40.40.9-0.70.40.60.40.60.60.60.70.60.60.60.60.8-0.60.60.6-0.90.70.7-0.70.7-0.7-0.70.80.8
Condit. Reinf. inactive responses2.02.32.6-1.61.51.51.51.51.51.51.51.51.51.51.51.6-1.51.51.5-1.61.51.5-1.51.5-1.5-1.51.51.5
Incentive salience index mean0.10.10.3-0.30.10.20.10.20.20.20.40.20.20.30.30.4-0.30.30.3-0.50.30.3-0.30.3-0.3-0.30.40.5
Condit. Reinf. lever presses0.91.21.7-1.10.81.00.81.01.01.01.21.01.01.01.11.2-1.01.01.1-1.31.11.1-1.11.1-1.1-1.11.21.3
Condit. Reinf. active minus inactive responses4.15.16.0-2.32.12.22.12.22.22.22.32.22.22.22.32.3-2.22.22.3-2.52.32.3-2.32.2-2.3-2.32.32.3
Condit. Reinf. active-inactive response ratio1.11.21.7-1.11.01.10.91.11.11.11.11.11.11.11.11.1-1.11.11.1-1.31.11.1-1.11.1-1.1-1.11.21.2
Condit. Reinf. active responses3.34.65.5-2.22.02.12.12.12.12.12.12.12.12.12.22.2-2.12.12.1-2.32.12.1-2.12.1-2.1-2.22.22.2
Condit. Reinf. inactive responses1.92.32.6-1.61.41.51.61.51.51.51.61.51.51.51.51.6-1.51.51.5-1.61.51.5-1.51.5-1.5-1.61.61.5
Condit. Reinf. lever presses2.33.13.5-1.91.61.71.71.71.71.71.81.71.71.71.71.9-1.81.81.8-1.91.81.8-1.81.7-1.8-1.81.81.8
Condit. Reinf. lever reinforcers received2.84.04.6-2.11.92.01.92.02.02.02.02.02.02.02.02.0-2.02.02.0-2.12.02.0-2.01.9-2.0-2.02.02.0
Conditioned reinforcement - actives0.30.31.5-0.71.20.61.10.70.70.60.30.60.60.60.50.3-0.50.50.50.40.40.4-0.40.5-0.4-0.30.0-0.1
Conditioned reinforcement - inactives2.22.53.8-1.71.81.91.71.81.71.71.41.71.71.61.71.4-1.71.61.5-1.61.51.6-1.51.5-1.4-1.51.21.1
Conditioned locomotion0.20.31.80.20.3-0.30.0-0.2-0.2-0.2-0.6-0.3-0.2-0.3-0.4-0.70.4-0.4-0.41.3-0.5-0.50.5-0.40.60.6-0.9-1.0
Patch foraging indifference point 0 sec0.40.60.70.6-0.8-0.7-0.9-0.8-0.8-0.8-0.7-0.8-0.8-0.8-0.8-0.80.8-0.8-0.80.7-0.8-0.80.8-0.70.70.8-0.7-0.7
Patch foraging indifference point AUC1.92.23.6-1.71.91.51.81.61.61.61.41.51.61.51.41.5-1.51.51.5-1.11.41.4-1.41.5-1.4-1.41.21.1
Delay disc. indifference point, 0s delay1.71.84.41.8-1.9-1.6-2.1-1.5-1.5-1.4-1.0-1.4-1.4-1.4-1.2-1.11.5-1.5-1.20.9-1.1-1.41.3-1.01.21.3-0.8-0.5
Delay disc. indifference point, 16s delay1.01.02.6-0.90.30.70.40.80.80.81.20.90.80.90.91.2-0.90.91.0-1.41.11.0-1.01.1-1.1-1.11.51.6
Delay disc. indifference point, 2s delay0.10.20.40.5-0.5-0.5-0.6-0.4-0.4-0.4-0.3-0.4-0.4-0.4-0.4-0.40.5-0.5-0.40.3-0.3-0.40.4-0.30.30.4-0.3-0.2
Delay disc. indifference point, 24s delay4.24.08.4-2.00.81.61.01.61.61.72.31.71.71.81.92.3-1.81.82.0-2.82.12.0-2.12.1-2.2-2.22.72.9
Delay disc. indifference point, 4s delay0.00.00.10.00.10.1-0.20.10.20.20.30.20.20.20.20.1-0.10.10.2-0.20.30.1-0.10.3-0.2-0.10.20.4
Delay disc. indifference point, 8s delay0.70.72.2-0.60.00.50.00.50.50.61.00.60.60.70.81.0-0.60.60.8-1.40.90.7-0.81.0-0.9-0.81.31.5
Indifference point function ln k0.00.00.10.3-0.2-0.1-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.20.2-0.2-0.20.0-0.2-0.20.2-0.20.20.2-0.2-0.2
Indifference point function log k0.00.00.10.3-0.2-0.1-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.20.2-0.2-0.20.0-0.2-0.20.2-0.20.20.2-0.2-0.2
Patch foraging total patch changes 0 sec0.20.40.60.5-0.7-0.6-0.7-0.6-0.7-0.6-0.6-0.6-0.6-0.6-0.7-0.60.6-0.6-0.60.5-0.6-0.60.6-0.50.60.6-0.6-0.5
Patch foraging total patch changes 12 sec0.81.01.31.0-0.9-1.0-1.1-1.0-1.0-1.0-0.9-1.0-1.0-1.0-1.0-1.01.0-1.0-1.01.1-1.0-1.01.0-0.81.01.0-1.0-0.9
Patch foraging total patch changes 18 sec0.00.00.1-0.00.0-0.1-0.0-0.1-0.2-0.2-0.3-0.2-0.2-0.2-0.2-0.20.2-0.2-0.20.4-0.2-0.20.2-0.20.20.3-0.4-0.4
Patch foraging total patch changes 24 sec1.11.42.31.2-0.9-1.1-1.1-1.1-1.1-1.1-1.2-1.1-1.1-1.1-1.2-1.21.1-1.1-1.21.5-1.2-1.21.2-1.11.21.2-1.3-1.3
Patch foraging total patch changes 6 sec0.00.00.1-0.1-0.1-0.2-0.1-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.3-0.20.2-0.2-0.20.1-0.2-0.20.2-0.10.20.2-0.2-0.2
Patch foraging time to switch 0 sec0.10.10.40.1-0.30.1-0.20.10.10.10.30.10.10.20.30.3-0.20.20.2-0.50.30.3-0.30.3-0.3-0.30.50.6
Patch foraging water rate 0 sec0.10.10.4-0.00.2-0.10.2-0.1-0.1-0.2-0.4-0.2-0.2-0.2-0.3-0.30.2-0.2-0.30.6-0.3-0.30.3-0.30.30.3-0.5-0.6
Patch foraging water rate 12 sec1.72.72.91.5-1.6-1.6-1.5-1.6-1.7-1.7-1.6-1.7-1.7-1.7-1.7-1.61.6-1.6-1.71.6-1.7-1.61.6-1.61.61.6-1.7-1.7
Patch foraging water rate 18 sec0.71.01.41.2-1.0-1.0-1.1-1.0-1.0-0.9-0.9-1.0-1.0-1.0-1.0-1.01.0-1.0-1.01.1-0.9-1.01.0-0.81.01.0-1.0-0.9
Patch foraging water rate 24 sec2.02.73.31.6-1.8-1.8-1.6-1.7-1.7-1.7-1.7-1.7-1.7-1.7-1.7-1.61.7-1.7-1.61.6-1.6-1.61.6-1.81.61.6-1.5-1.4
Patch foraging water rate 6 sec1.52.22.61.4-1.3-1.5-1.3-1.4-1.4-1.5-1.5-1.5-1.4-1.5-1.5-1.51.4-1.5-1.51.6-1.5-1.51.5-1.61.51.5-1.5-1.6
Seeking ratio, delayed vs. immediate footshock0.30.42.00.90.0-0.4-0.1-0.3-0.3-0.3-0.7-0.4-0.4-0.4-0.5-0.70.5-0.5-0.51.4-0.5-0.60.6-0.50.70.7-0.9-0.9
Distance traveled before self-admin0.00.00.10.20.20.10.30.20.20.20.20.20.20.20.20.3-0.20.20.20.10.20.2-0.20.2-0.2-0.20.30.4
Distance traveled after self-admin0.50.60.80.9-0.7-0.8-0.5-0.8-0.8-0.8-0.8-0.8-0.8-0.8-0.9-0.60.7-0.7-0.80.9-0.8-0.70.7-0.80.70.6-0.7-0.7
Extensor digitorum longus weight4.718.519.7-4.34.24.34.14.34.34.34.44.34.34.34.34.4-4.34.34.3-4.24.34.3-4.34.4-4.3-4.34.34.3
Bone: elastic displacement0.91.01.4-1.00.80.90.81.01.01.01.11.01.01.01.01.1-1.01.01.0-1.11.01.0-1.01.0-1.1-1.01.11.2
Bone: elastic work1.31.62.2-1.41.11.21.11.21.21.21.41.21.21.21.31.4-1.31.31.3-1.51.31.3-1.31.3-1.3-1.31.41.4
Bone: endosteal estimation0.40.81.0-0.91.00.91.00.90.90.90.90.90.90.90.90.8-0.90.90.9-0.80.90.9-0.90.9-0.9-0.80.80.7
Bone: endosteal perimeter0.10.30.3-0.50.60.60.50.60.60.60.60.60.60.60.60.5-0.60.60.6-0.60.50.6-0.60.6-0.6-0.60.50.5
Epididymis fat weight15.335.637.26.0-5.9-6.1-6.0-6.0-6.0-6.0-6.0-6.0-6.0-6.0-6.0-6.06.0-6.0-5.95.9-5.9-6.06.0-5.96.05.9-5.8-5.7
Delta time in closed arm before/after self-admin0.00.00.00.1-0.1-0.1-0.2-0.1-0.2-0.2-0.0-0.2-0.2-0.2-0.2-0.10.1-0.1-0.20.0-0.2-0.10.1-0.00.10.1-0.1-0.2
Delta time in open arm before/after self-admin0.30.30.6-0.30.50.60.50.60.60.60.60.60.60.60.60.6-0.60.60.6-0.40.70.5-0.50.6-0.6-0.50.60.7
Diff in mean of infusions in LGA sessions0.10.20.4-0.60.50.30.60.40.40.40.20.40.40.40.40.3-0.30.30.4-0.50.40.3-0.30.2-0.3-0.30.40.3
Delay discount exponential model param1.01.13.10.8-0.2-0.7-0.2-0.7-0.8-0.9-1.3-0.9-0.9-0.9-1.0-1.20.9-0.9-1.11.4-1.2-1.01.0-1.31.21.1-1.5-1.8
Extinction: sum of active levers before priming0.70.71.2-0.90.60.80.60.80.80.81.00.80.80.80.80.9-0.80.80.9-1.00.90.9-0.91.0-0.9-0.91.01.1
Active lever presses in extinction session 60.10.10.4-0.20.60.30.60.30.40.30.20.30.30.30.30.2-0.30.30.30.20.20.3-0.30.2-0.2-0.30.1-0.0
Bone: final force0.10.10.2-0.10.50.40.30.40.40.40.40.40.40.40.40.2-0.40.40.4-0.10.40.3-0.30.4-0.3-0.30.30.3
Bone: final moment0.10.20.3-0.10.50.50.40.50.50.50.50.50.50.50.40.3-0.40.40.4-0.20.40.4-0.40.5-0.4-0.40.30.4
Food consumed during 24 hour testing period0.20.30.4-0.50.60.60.60.50.50.50.50.50.50.50.50.5-0.50.50.5-0.40.50.5-0.50.5-0.5-0.50.40.4
Glucose0.30.50.70.8-0.5-0.6-0.6-0.6-0.6-0.6-0.7-0.7-0.7-0.7-0.7-0.70.7-0.7-0.70.8-0.7-0.70.7-0.60.70.7-0.8-0.8
Heart weight10.314.617.04.0-3.4-3.7-3.7-3.7-3.7-3.7-3.9-3.8-3.8-3.8-3.8-4.13.8-3.8-3.84.0-3.9-3.93.9-3.73.93.9-4.0-4.0
Delay discount hyperbolic model param0.90.92.50.7-0.3-0.7-0.2-0.7-0.7-0.8-1.2-0.8-0.8-0.9-0.9-1.10.8-0.8-1.01.3-1.1-0.90.9-1.21.11.0-1.4-1.6
Intermittent access intake day 1-15 change0.10.10.6-0.30.80.10.70.20.20.1-0.20.10.10.10.0-0.1-0.10.00.00.2-0.1-0.00.0-0.10.10.1-0.4-0.5
Intermittent access intake escalation0.10.10.6-0.10.5-0.10.5-0.1-0.1-0.1-0.4-0.1-0.1-0.2-0.2-0.40.2-0.2-0.20.5-0.3-0.30.3-0.30.30.3-0.6-0.8
Intermittent access intake escalation 20.60.51.70.60.1-0.50.0-0.5-0.5-0.6-0.9-0.6-0.6-0.6-0.7-0.90.6-0.6-0.71.0-0.8-0.70.7-0.80.80.8-1.2-1.3
Intermitt. access day 1 inactive lever presses0.00.10.3-0.10.30.50.30.30.30.2-0.00.20.20.20.20.0-0.30.30.1-0.20.10.2-0.20.0-0.0-0.1-0.2-0.2
Intermitt. access day 15 inactive lever presses5.66.211.2-2.63.32.93.32.82.82.72.22.62.62.62.52.2-2.62.62.4-1.52.32.4-2.42.3-2.3-2.21.61.4
Intermitt. access escalation Index0.40.30.80.6-0.0-0.4-0.1-0.4-0.4-0.4-0.7-0.5-0.5-0.5-0.6-0.70.5-0.5-0.60.8-0.6-0.60.6-0.60.60.7-0.9-0.9
Intermittent access day 1 total infusions4.65.46.5-2.42.42.52.42.42.42.42.32.42.42.42.42.2-2.42.42.3-2.22.32.3-2.32.3-2.3-2.22.12.0
Intermittent access day 15 total infusions1.71.93.8-1.61.91.61.81.51.51.51.21.41.41.41.41.2-1.41.41.3-1.11.21.3-1.31.3-1.2-1.20.90.8
Intermittent access terminal intake (last 3 days)1.31.43.0-1.41.71.41.61.41.31.31.01.31.31.21.21.0-1.21.21.1-0.81.01.1-1.11.1-1.1-1.10.70.6
Intermittent access total infusions1.61.72.4-1.51.51.51.41.41.41.41.21.41.41.41.31.2-1.31.31.3-1.21.31.3-1.31.3-1.3-1.21.11.0
Intermittent access day 1 locomotion2.22.42.7-1.41.51.61.41.61.61.61.51.61.61.61.61.5-1.61.61.5-1.51.51.5-1.51.5-1.5-1.51.51.5
Intermittent access day 15 total locomotion0.50.50.9-0.90.90.80.80.80.80.80.60.70.70.70.70.5-0.70.70.7-0.80.60.6-0.60.6-0.6-0.60.50.4
Intermittent access total locomotion0.10.10.3-0.50.50.50.40.50.50.40.30.40.40.40.40.2-0.40.40.4-0.30.40.3-0.30.3-0.3-0.30.20.2
Intermittent access standard deviation0.00.00.20.00.40.30.40.30.20.2-0.00.20.20.20.2-0.0-0.20.20.10.30.10.1-0.10.0-0.0-0.1-0.1-0.2
Left kidney weight0.00.00.10.2-0.20.0-0.3-0.0-0.0-0.00.0-0.0-0.0-0.00.0-0.0-0.00.0-0.0-0.10.00.0-0.0-0.0-0.0-0.00.10.1
Right kidney weight0.72.14.11.6-1.9-1.5-2.0-1.6-1.6-1.5-1.3-1.5-1.5-1.5-1.4-1.51.5-1.4-1.40.8-1.4-1.41.4-1.31.31.3-1.0-0.9
Cocaine induced anxiety0.20.20.7-0.50.90.60.80.50.50.50.20.50.50.40.40.2-0.40.40.3-0.20.30.3-0.30.3-0.3-0.30.0-0.1
Post-drug Anxiety0.60.70.80.9-0.7-0.8-0.7-0.8-0.8-0.8-0.9-0.8-0.8-0.8-0.8-0.90.8-0.8-0.80.8-0.8-0.80.8-0.80.80.8-0.9-0.9
Baseline Anxiety0.80.91.91.1-1.4-1.1-1.4-1.1-1.0-1.0-0.8-1.0-1.0-1.0-0.9-0.81.0-1.0-0.90.7-0.8-0.90.9-0.80.80.8-0.5-0.4
Tail length0.20.51.00.5-0.5-0.8-0.4-0.7-0.7-0.7-0.8-0.7-0.7-0.7-0.7-0.70.7-0.7-0.71.0-0.7-0.70.7-0.80.70.7-0.7-0.8
Length with tail1.55.46.22.4-2.3-2.5-2.4-2.4-2.4-2.3-2.2-2.3-2.3-2.3-2.4-2.42.4-2.4-2.32.5-2.3-2.32.3-2.22.32.3-2.2-2.2
Length without tail0.61.32.11.2-1.2-1.2-1.5-1.2-1.2-1.1-1.0-1.2-1.2-1.1-1.1-1.21.2-1.2-1.11.0-1.1-1.11.1-1.01.11.1-1.0-1.0
Times rat made contact with spout2.63.03.6-1.71.51.71.51.71.71.71.81.71.71.71.71.8-1.71.71.7-1.91.71.8-1.81.8-1.8-1.81.91.9
Lifetime Intake2.12.43.2-1.81.81.71.71.71.71.61.51.61.61.61.61.4-1.61.61.5-1.41.51.5-1.51.5-1.5-1.41.31.2
Liver weight, left1.32.12.31.2-1.4-1.4-1.4-1.4-1.4-1.4-1.4-1.4-1.4-1.4-1.5-1.41.4-1.4-1.51.5-1.5-1.41.5-1.41.41.4-1.5-1.5
Liver weight, right9.215.316.14.0-3.8-3.9-3.7-3.9-3.9-3.9-4.0-3.9-3.9-3.9-4.0-3.93.9-3.9-3.94.0-4.0-3.93.9-3.93.93.9-4.0-4.0
Locomotor activity0.10.10.70.6-0.8-0.4-0.9-0.4-0.4-0.3-0.0-0.3-0.3-0.3-0.2-0.10.3-0.3-0.2-0.3-0.1-0.20.2-0.10.10.20.20.3
Locomotor testing distance0.30.41.2-0.20.20.50.10.50.50.60.80.60.60.60.70.7-0.60.60.7-1.00.70.6-0.70.7-0.7-0.70.91.1
Locomotor testing rearing0.60.91.1-0.90.90.90.90.90.91.01.01.01.01.01.00.9-1.01.01.0-0.81.01.0-1.00.9-1.0-1.01.01.0
Locomotion in novel chamber1.21.53.31.4-1.1-1.4-1.3-1.2-1.2-1.1-1.1-1.2-1.1-1.1-1.3-1.21.2-1.2-1.11.8-1.1-1.21.2-1.11.21.1-1.1-1.0
Locomotion in novel chamber post-restriction2.02.43.81.8-2.0-1.7-1.7-1.6-1.6-1.6-1.5-1.6-1.6-1.6-1.5-1.31.5-1.5-1.51.7-1.5-1.51.5-1.61.41.4-1.2-1.2
Fecal boli incidents, locomotor time 10.30.40.70.10.60.50.20.60.60.70.80.60.60.70.60.5-0.60.60.7-0.30.70.6-0.60.8-0.6-0.60.70.9
Change in fecal boli incidents, locomotor task4.24.04.61.9-2.2-2.0-2.0-2.1-2.1-2.1-2.0-2.1-2.1-2.1-2.0-1.92.0-2.0-2.01.9-2.0-1.91.9-2.11.91.9-1.9-1.9
Time >=10cm from walls, locomotor time 10.10.10.4-0.1-0.4-0.0-0.6-0.1-0.1-0.00.4-0.0-0.00.00.00.2-0.00.00.1-0.40.20.1-0.10.4-0.2-0.10.40.6
Bouts of movement, locomotor time 12.83.14.2-1.31.61.61.41.71.81.81.91.81.81.81.81.8-1.71.71.8-1.41.91.7-1.72.0-1.8-1.71.92.1
Total resting periods, locomotor time 12.93.24.0-1.31.81.71.51.81.81.91.91.81.81.91.81.8-1.81.81.9-1.51.91.7-1.72.0-1.8-1.71.82.0
Rest time, locomotor task time 10.00.00.1-0.00.20.20.10.20.20.20.10.20.20.20.10.0-0.10.10.10.10.10.1-0.10.2-0.1-0.10.10.1
Distance moved, locomotor task time 10.80.91.30.7-1.1-1.0-1.0-1.0-1.1-1.1-0.9-1.1-1.1-1.1-1.1-0.81.0-1.0-1.00.7-1.0-0.90.9-1.00.90.9-0.8-0.8
Vertical activity count, locomotor time 10.30.30.50.2-0.7-0.6-0.5-0.6-0.6-0.6-0.5-0.6-0.6-0.6-0.6-0.30.5-0.5-0.60.2-0.6-0.50.5-0.60.40.4-0.4-0.4
Time >=10cm from walls, locomotor time 20.00.00.2-0.20.30.20.10.20.20.20.20.20.20.20.10.0-0.10.10.10.40.10.1-0.10.3-0.1-0.0-0.0-0.0
Bouts of movement, locomotor time 20.10.10.40.6-0.3-0.3-0.5-0.3-0.2-0.2-0.1-0.2-0.2-0.2-0.3-0.30.3-0.3-0.20.2-0.2-0.30.3-0.00.30.3-0.2-0.1
Total resting periods, locomotor time 20.00.00.10.30.1-0.0-0.20.00.00.00.10.00.00.0-0.0-0.10.0-0.00.00.10.0-0.00.00.20.10.0-0.10.0
Rest time, locomotor task time 21.71.92.6-1.31.31.41.31.41.41.41.51.41.41.41.41.4-1.31.31.4-1.61.41.4-1.41.4-1.4-1.41.41.4
Distance moved, locomotor task time 21.11.32.00.7-1.1-1.1-1.0-1.1-1.2-1.2-1.2-1.2-1.2-1.2-1.2-1.11.1-1.1-1.21.4-1.2-1.11.1-1.21.11.1-1.2-1.3
Vertical activity count, locomotor time 20.80.92.00.5-0.7-0.9-0.7-0.9-0.9-0.9-1.0-0.9-0.9-0.9-1.0-0.90.9-0.9-1.01.4-1.0-0.91.0-1.00.91.0-1.1-1.2
Light reinforcement 14.58.18.7-2.92.93.02.92.92.92.92.92.92.92.92.82.9-2.92.92.8-2.62.82.9-2.92.9-2.8-2.82.72.7
Light reinforcement 23.95.26.0-2.32.42.42.32.42.42.32.32.32.32.32.32.2-2.32.32.3-2.22.22.3-2.32.4-2.2-2.22.12.0
Bone: marrow area0.40.81.0-1.01.01.01.01.00.90.90.90.90.90.90.90.9-0.90.90.9-0.90.90.9-0.90.9-0.9-0.90.80.8
Bone: maximum diameter0.91.71.8-1.31.31.31.21.31.31.31.31.31.31.31.31.3-1.31.31.3-1.31.31.3-1.31.3-1.3-1.31.21.2
Bone: maximum force0.00.00.00.20.20.10.00.10.10.10.10.10.10.10.1-0.1-0.10.10.10.20.10.0-0.00.2-0.0-0.0-0.0-0.0
Bone: maximum moment0.00.00.10.10.30.20.10.20.20.20.20.20.20.20.20.1-0.20.20.20.00.20.2-0.20.3-0.2-0.10.10.1
Mean time between licks in bursts2.43.33.71.9-1.9-1.9-1.9-1.9-1.9-1.8-1.8-1.8-1.8-1.8-1.8-1.81.8-1.8-1.81.6-1.8-1.81.8-1.81.81.8-1.7-1.7
Mean num. licks in bursts0.10.10.2-0.10.40.30.40.30.30.30.30.30.30.30.30.3-0.30.30.3-0.10.30.3-0.30.3-0.3-0.30.20.2
Cd content in liver0.00.00.00.10.10.0-0.00.10.10.10.10.10.10.10.10.1-0.00.00.10.00.10.0-0.00.1-0.1-0.00.10.1
Co content in liver5.96.97.5-2.62.62.62.42.62.62.62.72.62.62.62.72.7-2.62.62.7-2.72.72.6-2.62.7-2.6-2.62.72.7
Cu content in liver0.00.00.0-0.10.20.10.20.20.20.20.20.20.20.20.20.2-0.20.20.2-0.20.20.2-0.20.2-0.2-0.20.20.2
Fe content in liver0.10.10.20.4-0.1-0.2-0.2-0.2-0.2-0.2-0.3-0.2-0.2-0.2-0.3-0.30.3-0.3-0.30.5-0.3-0.30.3-0.20.30.3-0.4-0.4
K content in liver0.10.10.10.3-0.1-0.2-0.1-0.2-0.2-0.2-0.3-0.2-0.2-0.2-0.2-0.30.2-0.2-0.30.3-0.3-0.20.2-0.30.30.2-0.3-0.4
Mg content in liver0.20.20.30.5-0.3-0.3-0.3-0.4-0.4-0.4-0.5-0.4-0.4-0.4-0.4-0.40.4-0.4-0.40.5-0.4-0.40.4-0.50.40.4-0.5-0.5
Mn content in liver0.50.50.8-0.70.80.80.90.80.80.70.70.80.80.70.70.7-0.80.80.7-0.50.70.8-0.80.6-0.7-0.70.60.6
Na content in liver0.30.30.7-0.40.80.70.80.70.70.60.50.60.60.60.60.5-0.60.60.6-0.30.60.5-0.50.6-0.5-0.50.40.3
Rb content in liver0.00.00.10.3-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.10.1-0.1-0.10.2-0.1-0.10.1-0.10.10.1-0.1-0.1
Se content in liver0.50.71.10.9-0.6-0.7-0.6-0.7-0.7-0.8-0.9-0.8-0.8-0.8-0.8-0.90.8-0.8-0.81.0-0.8-0.80.8-0.80.90.9-1.0-1.0
Sr content in liver0.00.00.10.1-0.3-0.2-0.3-0.2-0.2-0.2-0.1-0.2-0.2-0.2-0.1-0.10.2-0.2-0.1-0.0-0.1-0.10.1-0.10.10.1-0.00.0
Zn content in liver1.41.51.71.3-1.2-1.3-1.2-1.2-1.2-1.2-1.2-1.2-1.2-1.2-1.2-1.21.2-1.2-1.21.2-1.2-1.21.2-1.21.21.2-1.2-1.2
Bone: minimum diameter0.10.20.30.4-0.3-0.4-0.4-0.4-0.4-0.4-0.5-0.4-0.4-0.4-0.4-0.50.4-0.4-0.50.5-0.5-0.50.5-0.40.50.5-0.5-0.5
Time in familiar zone, hab. session 11.00.91.81.2-0.8-0.9-0.8-0.9-0.9-0.9-0.9-0.9-0.9-0.9-0.9-1.00.9-0.9-0.91.3-0.9-1.01.0-0.81.01.0-1.1-1.0
Time in novel zone, hab. session 10.70.60.80.6-0.9-0.8-0.9-0.8-0.9-0.8-0.9-0.8-0.8-0.8-0.8-0.80.8-0.8-0.80.6-0.8-0.80.8-0.90.80.8-0.7-0.7
Total zone transitions, hab. session 10.10.10.2-0.30.40.40.40.40.40.40.40.40.40.40.40.4-0.40.40.4-0.30.40.4-0.40.3-0.4-0.40.40.4
Total locomotion distance, hab. session 10.10.10.3-0.40.50.40.50.40.40.40.30.40.40.40.40.3-0.40.40.4-0.10.30.4-0.40.3-0.3-0.30.30.2
Locomotion velocity, hab. session 11.11.51.7-1.31.31.31.31.21.21.21.21.21.21.21.21.2-1.21.21.2-1.21.21.2-1.21.2-1.2-1.21.21.1
Time in familiar zone, hab. session 20.00.00.20.30.20.00.10.00.00.0-0.10.00.00.0-0.0-0.1-0.00.0-0.00.5-0.0-0.00.0-0.10.10.0-0.2-0.2
Time in novel zone, hab. session 20.40.40.70.4-0.9-0.7-0.8-0.7-0.7-0.7-0.5-0.7-0.7-0.7-0.6-0.60.7-0.7-0.60.2-0.6-0.60.6-0.50.60.6-0.4-0.4
Total zone transitions, hab. session 20.20.20.3-0.50.30.40.30.40.40.40.40.40.40.40.40.5-0.40.40.5-0.60.50.5-0.50.4-0.5-0.50.50.5
Total locomotion distance, hab. session 20.20.30.5-0.70.50.60.50.60.60.60.50.60.60.60.60.5-0.60.60.6-0.60.60.6-0.60.5-0.6-0.60.60.5
Locomotion velocity, hab. session 20.50.71.0-1.00.80.80.70.80.80.80.80.80.80.80.80.8-0.80.80.8-0.90.80.8-0.80.8-0.8-0.80.90.8
Novel to familiar place preference ratio0.70.71.20.7-1.1-1.0-1.0-1.0-1.0-0.9-0.7-0.9-0.9-0.9-0.9-0.70.9-0.9-0.90.5-0.8-0.90.9-0.70.80.8-0.7-0.6
Novelty place preference1.31.31.91.0-1.4-1.2-1.3-1.2-1.2-1.2-1.0-1.2-1.2-1.2-1.2-1.01.2-1.2-1.10.8-1.1-1.11.1-1.01.11.1-1.0-0.9
Time in novel zone, NPP test1.61.62.31.2-1.5-1.4-1.4-1.4-1.4-1.3-1.2-1.3-1.3-1.3-1.3-1.21.3-1.3-1.31.0-1.3-1.31.3-1.21.21.2-1.1-1.1
Total zone transitions, NPP test1.42.12.2-1.41.51.51.31.51.51.51.41.51.51.51.51.4-1.51.51.5-1.31.51.5-1.41.4-1.4-1.41.41.4
Total locomotion distance, NPP test1.92.62.9-1.71.71.71.61.71.71.71.61.71.71.61.61.5-1.61.61.6-1.51.61.6-1.61.6-1.6-1.61.61.5
Locomotion velocity, NPP test3.44.95.4-2.32.22.22.12.22.22.22.22.22.22.22.22.1-2.22.22.2-2.22.22.2-2.22.1-2.2-2.22.22.1
Intraocular pressure4.15.78.32.4-2.9-2.6-2.7-2.6-2.6-2.6-2.2-2.5-2.5-2.5-2.4-2.22.4-2.4-2.41.8-2.4-2.32.3-2.32.22.3-2.0-1.9
Delta distance traveled before/after self-admin1.61.72.31.2-1.1-1.2-1.1-1.3-1.3-1.3-1.4-1.3-1.3-1.3-1.4-1.41.3-1.3-1.31.4-1.4-1.31.3-1.41.31.3-1.5-1.5
Delta ambulatory time before/after self-admin0.30.30.60.4-0.3-0.5-0.3-0.5-0.5-0.6-0.7-0.6-0.6-0.6-0.6-0.60.5-0.5-0.60.7-0.6-0.60.6-0.60.60.6-0.7-0.8
Parametrial fat weight5.610.811.83.4-3.2-3.3-3.1-3.3-3.3-3.3-3.3-3.3-3.3-3.3-3.3-3.33.3-3.3-3.33.4-3.3-3.33.3-3.33.33.3-3.3-3.2
Pavlov. Cond. lever latency1.82.32.61.5-1.6-1.6-1.5-1.5-1.5-1.5-1.5-1.5-1.5-1.5-1.5-1.51.5-1.5-1.51.4-1.5-1.51.5-1.61.51.4-1.4-1.4
Pavlov. Cond. magazine entry latency0.00.00.1-0.00.20.20.20.20.20.20.10.10.10.10.10.1-0.10.10.10.00.10.1-0.10.1-0.1-0.10.10.1
Pavlov. Cond. change in total contacts0.10.10.1-0.20.20.20.20.20.20.20.30.20.20.20.20.3-0.20.20.2-0.30.30.2-0.20.3-0.2-0.20.20.3
Pavlov. Cond. index score0.81.01.1-0.91.11.01.01.01.01.01.01.01.01.01.01.0-1.01.01.0-0.91.01.0-1.01.0-1.0-0.90.90.9
Pavlov. Cond. latency score0.70.91.1-0.91.11.01.01.01.01.01.01.01.01.01.00.9-0.90.90.9-0.80.90.9-0.91.0-0.9-0.90.80.8
Pavlov. Cond. lever contacts1.21.41.6-1.21.21.21.11.21.21.21.31.21.21.21.21.2-1.21.21.2-1.21.21.2-1.21.3-1.2-1.21.21.2
Pavlov. Cond. magazine entry number0.40.50.70.6-0.8-0.8-0.8-0.8-0.8-0.7-0.7-0.7-0.7-0.7-0.7-0.70.7-0.7-0.70.5-0.7-0.70.7-0.70.70.7-0.6-0.6
Pavlov. Cond. intertrial magazine entries1.51.82.7-1.61.11.31.11.31.31.31.41.31.31.31.31.4-1.31.31.3-1.61.31.3-1.31.3-1.3-1.31.41.4
Pavlov. Cond. lever-magazine prob. diff.1.72.12.3-1.41.51.51.51.51.51.51.51.51.51.51.51.5-1.51.51.5-1.41.51.4-1.41.5-1.5-1.41.41.4
Pavlov. Cond. response bias1.51.82.0-1.21.41.41.41.41.41.41.41.41.41.41.41.4-1.41.41.4-1.21.41.4-1.31.4-1.3-1.31.31.3
Pavlov. Cond. lever latency1.82.52.81.7-1.5-1.6-1.6-1.6-1.6-1.6-1.6-1.6-1.6-1.6-1.6-1.61.6-1.6-1.61.5-1.6-1.61.6-1.51.61.6-1.5-1.5
Pavlov. Cond. magazine entry latency0.20.20.5-0.60.70.50.70.50.50.50.30.50.50.50.40.4-0.50.50.4-0.30.40.4-0.40.4-0.4-0.40.20.1
Pavlov. Cond. change in total contacts0.71.01.2-1.10.91.01.01.01.01.01.01.01.01.01.01.0-1.01.01.0-1.11.01.0-1.01.0-1.0-1.01.01.0
Pavlov. Cond. index score1.01.31.7-1.31.31.21.31.21.21.21.11.21.21.21.11.1-1.11.11.1-1.01.11.1-1.11.1-1.1-1.11.00.9
Pavlov. Cond. latency score1.01.21.7-1.21.31.21.31.21.11.11.01.11.11.11.11.1-1.11.11.1-0.91.01.1-1.11.0-1.0-1.00.90.8
Pavlov. Cond. lever contacts1.01.41.7-1.31.11.21.11.21.21.21.21.21.21.21.21.2-1.21.21.2-1.21.21.2-1.21.1-1.2-1.21.21.2
Pavlov. Cond. magazine entry number0.10.10.30.4-0.5-0.4-0.5-0.4-0.3-0.3-0.2-0.3-0.3-0.3-0.3-0.30.3-0.3-0.30.2-0.2-0.30.3-0.20.20.3-0.1-0.1
Pavlov. Cond. intertrial magazine entries3.24.25.72.0-2.3-2.1-2.4-2.1-2.1-2.1-2.0-2.1-2.1-2.1-2.0-2.12.1-2.1-2.01.8-2.0-2.02.0-2.02.02.0-1.8-1.8
Pavlov. Cond. lever-magazine prob. diff.0.70.91.2-1.11.11.01.11.01.01.00.91.01.01.00.90.9-1.01.00.9-0.90.90.9-0.90.9-0.9-0.90.80.7
Pavlov. Cond. response bias1.82.52.8-1.71.51.61.61.61.61.61.61.61.61.61.61.6-1.61.61.6-1.61.61.6-1.61.5-1.6-1.61.61.5
Time in closed arm before self-admin0.70.71.00.8-0.9-0.8-0.8-0.8-0.8-0.8-1.0-0.8-0.8-0.8-0.8-0.90.8-0.8-0.91.0-0.9-0.80.8-1.00.90.9-0.9-0.9
Time in closed arm after self-admin1.71.71.91.3-1.4-1.4-1.3-1.3-1.3-1.3-1.3-1.3-1.3-1.3-1.3-1.31.3-1.3-1.31.4-1.3-1.31.3-1.31.31.3-1.2-1.3
Time in open arm before self-admin0.20.21.1-0.60.20.40.30.30.30.30.50.30.30.30.40.5-0.40.40.4-1.10.40.5-0.50.5-0.5-0.50.60.7
Time in open arm after self-admin2.72.93.7-1.61.61.71.51.71.71.71.81.71.71.71.81.7-1.71.71.7-1.91.81.7-1.71.8-1.7-1.71.81.9
Bone: periosteal estimation0.61.21.4-1.11.21.21.11.11.11.11.11.11.11.11.11.1-1.11.11.1-1.01.11.1-1.11.1-1.1-1.11.01.0
Bone: periosteal perimeter0.20.40.4-0.50.60.60.50.60.60.60.70.60.60.60.60.6-0.60.60.6-0.60.60.6-0.60.7-0.6-0.60.60.6
Bone: post-yield work0.30.50.6-0.40.80.70.60.70.70.70.70.70.70.70.70.6-0.70.70.7-0.40.70.7-0.70.8-0.7-0.70.60.7
Progressive ratio test 1 active lever presses0.60.71.3-1.11.11.01.01.01.00.90.70.90.90.90.80.6-0.80.80.8-0.50.70.7-0.70.7-0.7-0.60.40.3
Progressive ratio test 1 breakpoint0.50.61.1-1.01.11.00.90.90.90.90.60.80.80.80.80.6-0.80.80.7-0.50.70.7-0.70.7-0.6-0.60.40.3
Progressive ratio test 1 inactive lever presses1.82.04.6-1.52.11.72.01.71.61.61.11.51.51.51.41.1-1.51.41.3-0.71.21.3-1.31.2-1.1-1.20.70.5
Progressive ratio test 2 active lever presses0.00.00.3-0.10.30.10.10.00.0-0.0-0.3-0.0-0.0-0.1-0.1-0.30.1-0.1-0.20.4-0.2-0.10.1-0.20.20.2-0.4-0.5
Progressive ratio test 2 breakpoint0.00.00.2-0.10.30.10.20.10.10.0-0.20.00.00.0-0.0-0.20.0-0.0-0.10.3-0.1-0.10.1-0.10.10.1-0.3-0.4
Progressive ratio test 2 inactive lever presses1.01.23.1-1.31.71.41.61.31.31.20.81.21.21.11.10.8-1.11.11.0-0.50.91.0-0.90.9-0.9-0.80.40.2
Incentive Sensitization - Responses0.20.20.40.3-0.1-0.3-0.1-0.3-0.3-0.3-0.5-0.4-0.3-0.4-0.4-0.50.4-0.4-0.40.4-0.4-0.40.4-0.40.40.4-0.6-0.6
Incentive Sensitization - Breakpoint0.40.40.90.6-0.2-0.5-0.3-0.5-0.5-0.5-0.7-0.6-0.6-0.6-0.6-0.80.6-0.6-0.60.7-0.7-0.60.6-0.70.60.7-0.8-0.9
Sum of active levers in priming session hrs 5-61.21.21.4-1.10.91.11.11.11.01.01.11.11.11.11.11.2-1.11.11.1-1.11.11.2-1.21.0-1.2-1.21.11.1
Progressive ratio0.10.10.9-0.4-0.0-0.00.2-0.1-0.2-0.3-0.5-0.3-0.3-0.3-0.4-0.40.2-0.2-0.40.4-0.5-0.20.3-0.50.30.3-0.7-0.9
Food seeking constrained by brief footshock2.73.34.6-2.12.21.92.11.91.91.91.71.91.91.91.81.7-1.81.71.8-1.91.71.7-1.71.8-1.7-1.61.51.4
Seeking ratio, punishment vs. effort1.01.22.3-0.70.90.90.71.01.01.11.21.01.01.11.11.2-0.91.01.2-1.31.21.0-1.01.3-1.1-1.01.31.5
Retroperitoneal fat weight22.072.181.09.0-8.5-8.4-8.7-8.5-8.5-8.5-8.5-8.5-8.5-8.5-8.5-8.68.5-8.5-8.58.3-8.5-8.58.5-8.38.58.5-8.3-8.2
Reaction time number correct0.60.91.1-0.90.90.91.00.90.90.90.90.90.90.90.91.0-1.01.00.9-0.90.91.0-1.00.9-0.9-1.00.90.9
Reaction time mean minus median0.00.00.00.1-0.1-0.1-0.2-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.10.2-0.2-0.10.2-0.1-0.20.2-0.00.10.2-0.1-0.1
Reaction time mean minus median AUC0.10.10.20.2-0.3-0.3-0.4-0.3-0.3-0.2-0.2-0.3-0.3-0.3-0.3-0.20.3-0.3-0.20.3-0.2-0.30.3-0.20.20.3-0.2-0.2
Reaction time num false alarms0.30.41.1-0.60.20.60.20.50.40.50.70.50.50.50.60.7-0.60.60.6-1.00.60.6-0.60.6-0.7-0.70.80.9
Reaction time num false alarms AUC0.40.61.6-0.80.30.70.30.60.60.60.90.60.60.60.80.8-0.70.70.7-1.30.80.8-0.80.8-0.8-0.81.01.1
Reaction time trials correct on left0.60.91.1-0.90.90.91.00.90.90.90.90.90.90.90.91.0-1.01.00.9-0.90.91.0-1.00.9-0.9-1.00.90.9
Reaction time trials on left0.71.01.1-1.01.01.01.11.01.01.00.91.01.01.01.01.0-1.01.01.0-1.01.01.0-1.00.9-1.0-1.01.01.0
Reaction time mean1.11.61.81.1-1.3-1.3-1.3-1.3-1.3-1.3-1.3-1.3-1.3-1.3-1.3-1.31.3-1.3-1.31.0-1.3-1.31.3-1.31.21.3-1.2-1.2
Reaction time mean AUC1.01.31.51.0-1.2-1.1-1.2-1.2-1.2-1.2-1.2-1.2-1.2-1.2-1.1-1.11.1-1.1-1.20.8-1.2-1.11.1-1.21.11.1-1.1-1.1
Median of all reaction times1.11.61.81.1-1.3-1.2-1.3-1.3-1.3-1.3-1.3-1.3-1.3-1.3-1.3-1.31.2-1.2-1.30.9-1.3-1.21.2-1.41.21.2-1.2-1.2
Reaction time omissions0.10.10.2-0.50.30.30.30.30.30.30.20.30.30.30.30.3-0.30.30.3-0.30.30.3-0.30.2-0.3-0.30.30.3
Reaction time false alarm rate0.00.10.4-0.2-0.30.1-0.30.00.00.00.30.10.00.10.20.2-0.10.10.1-0.70.20.2-0.20.2-0.2-0.20.40.5
Reaction time premature initiation rate0.20.20.50.7-0.6-0.5-0.7-0.5-0.5-0.4-0.3-0.4-0.4-0.4-0.4-0.40.5-0.5-0.40.3-0.4-0.50.5-0.20.40.5-0.3-0.2
Reaction time premature initiations0.00.00.10.1-0.00.1-0.10.10.10.10.20.10.10.10.20.2-0.10.10.1-0.20.20.1-0.10.3-0.2-0.10.20.3
Std. dev. reaction times0.40.60.70.7-0.7-0.7-0.8-0.7-0.7-0.7-0.8-0.8-0.8-0.8-0.7-0.80.8-0.8-0.80.7-0.8-0.80.8-0.80.80.8-0.8-0.8
Reaction time trials completed0.71.01.1-1.01.01.01.11.01.01.00.91.01.01.01.01.0-1.01.01.0-1.01.01.0-1.00.9-1.0-1.01.01.0
Reaction time trials AUC0.81.21.5-1.11.11.11.21.11.11.11.11.11.11.11.11.1-1.11.11.1-1.11.11.1-1.11.0-1.1-1.11.11.1
Run reversals in cocaine runway, females0.00.00.2-0.1-0.4-0.1-0.3-0.1-0.1-0.10.2-0.1-0.1-0.1-0.00.20.1-0.10.0-0.40.1-0.0-0.00.2-0.0-0.00.30.4
Run reversals in cocaine runway, males0.40.40.9-0.40.20.50.50.50.50.50.70.50.50.50.60.9-0.60.60.6-0.70.60.7-0.70.6-0.7-0.70.90.9
Latency to leave start box in cocaine runway0.40.40.9-0.91.00.60.80.70.70.70.50.70.70.70.60.5-0.70.70.7-0.30.60.7-0.70.5-0.6-0.70.60.5
Latency to leave start box in cocaine runway, F0.70.71.3-1.11.00.81.00.80.80.80.80.80.80.80.80.8-0.90.90.8-1.00.80.9-0.90.7-0.8-0.90.80.8
Latency to leave start box in cocaine runway, M0.20.20.7-0.50.80.40.60.50.50.50.30.50.50.50.40.2-0.50.50.40.40.40.4-0.40.4-0.4-0.40.20.1
Std. dev. time between licks in bursts0.10.10.30.5-0.2-0.3-0.3-0.3-0.2-0.3-0.3-0.3-0.3-0.3-0.3-0.40.3-0.3-0.30.5-0.3-0.40.4-0.20.40.4-0.4-0.4
Total sessions with >9 infusions1.11.22.0-1.41.31.31.31.21.21.21.11.21.21.21.11.0-1.21.11.1-0.61.01.1-1.01.1-1.0-1.00.80.7
Short access day 1 total inactive lever presses4.14.56.3-2.22.42.42.52.32.32.22.02.22.22.22.22.1-2.22.22.1-2.12.02.1-2.02.0-2.0-1.91.71.6
Short access day 10 total inactive lever presses0.91.01.5-1.01.11.21.21.11.11.00.91.01.01.01.01.0-1.01.00.9-1.00.91.0-1.00.9-0.9-0.90.70.7
Short access day 1 total infusions2.93.14.8-2.12.22.02.21.91.91.91.61.91.91.81.71.6-1.81.81.7-1.41.61.7-1.61.6-1.6-1.61.31.1
Short access day 10 total infusions3.23.54.2-2.02.02.01.92.02.02.01.82.02.01.91.91.8-1.91.91.9-1.71.91.8-1.81.9-1.8-1.81.71.6
Short access total infusions1.71.92.9-1.51.71.61.61.51.51.51.31.51.51.51.41.3-1.41.41.4-1.11.31.3-1.31.3-1.3-1.21.00.9
Short access day 1 locomotion4.64.96.9-2.52.62.42.52.42.42.32.12.32.32.32.22.1-2.22.22.2-1.72.12.2-2.22.2-2.1-2.11.91.7
Short access day 10 total locomotion0.50.60.9-0.60.90.90.70.90.90.90.70.90.90.90.80.6-0.80.80.8-0.50.80.7-0.70.8-0.6-0.70.60.6
Short access total locomotion0.20.20.4-0.40.70.70.50.60.60.60.40.60.60.60.50.3-0.50.50.5-0.20.50.4-0.50.5-0.3-0.40.30.2
One hour access (0.3 mA shock)1.51.82.5-1.61.61.51.51.41.41.41.21.41.31.31.31.2-1.41.41.3-1.31.21.3-1.31.3-1.3-1.31.11.0
Compulsive drug intake0.10.10.50.2-0.7-0.3-0.5-0.4-0.4-0.3-0.0-0.3-0.3-0.3-0.20.00.2-0.2-0.2-0.1-0.1-0.10.1-0.10.00.10.10.2
One hour access (shock baseline)1.11.22.1-1.51.41.21.21.21.21.21.01.21.21.21.10.9-1.11.11.1-0.91.01.1-1.11.0-1.0-1.00.80.7
Social response proportion0.50.60.90.5-0.5-0.7-0.6-0.7-0.7-0.7-0.8-0.7-0.7-0.7-0.8-0.80.7-0.7-0.80.8-0.8-0.80.8-0.70.80.8-0.9-0.9
Social responses0.20.20.60.2-0.2-0.3-0.2-0.4-0.4-0.4-0.6-0.4-0.4-0.4-0.4-0.60.4-0.4-0.50.7-0.5-0.50.5-0.50.50.5-0.7-0.8
Social time1.21.53.30.9-0.5-1.0-0.7-1.0-1.0-1.1-1.4-1.1-1.1-1.1-1.2-1.41.2-1.2-1.21.6-1.3-1.31.3-1.21.41.4-1.7-1.8
Soleus weight5.014.716.4-3.83.53.83.53.73.83.84.03.83.83.83.84.0-3.83.83.9-4.03.93.9-3.93.9-3.9-3.94.04.1
Bone: stiffness0.00.00.10.3-0.0-0.2-0.2-0.2-0.1-0.2-0.2-0.2-0.2-0.2-0.2-0.30.2-0.2-0.20.4-0.2-0.20.2-0.10.20.2-0.3-0.3
Tibialis anterior weight3.813.014.0-3.63.63.63.43.63.63.63.73.63.63.63.63.7-3.63.63.6-3.53.63.6-3.63.7-3.6-3.63.63.6
Time to tail flick, vehicle, before self-admin2.62.73.21.5-1.7-1.7-1.8-1.7-1.7-1.7-1.6-1.7-1.7-1.7-1.6-1.71.7-1.7-1.61.5-1.6-1.71.7-1.51.61.7-1.6-1.5
Time to tail flick, vehicle, after self-admin4.85.16.22.5-2.3-2.3-2.4-2.3-2.3-2.2-2.3-2.2-2.2-2.2-2.2-2.32.3-2.3-2.22.1-2.2-2.32.3-2.22.32.3-2.1-2.1
Time to tail flick, test, before self-admin0.50.50.6-0.60.70.70.60.70.70.70.70.70.70.70.70.7-0.70.70.7-0.80.70.7-0.70.7-0.7-0.70.70.7
Time to tail flick, test, after self-admin0.10.10.20.2-0.4-0.3-0.5-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.40.4-0.3-0.30.4-0.3-0.30.3-0.30.30.3-0.3-0.3
Delta time to tail flick, vehicle, before/after SA0.10.10.20.4-0.2-0.2-0.2-0.2-0.2-0.2-0.3-0.2-0.2-0.2-0.2-0.30.2-0.2-0.20.3-0.2-0.20.2-0.20.30.3-0.2-0.2
Delta time to tail flick, test, before/after SA0.30.30.6-0.80.60.60.60.60.60.60.50.60.60.60.60.5-0.60.60.5-0.50.50.5-0.50.5-0.5-0.50.50.5
Tibia length2.77.68.82.7-2.5-2.7-2.5-2.7-2.7-2.7-2.8-2.7-2.7-2.7-2.8-2.92.7-2.7-2.83.0-2.8-2.82.8-2.72.82.8-2.9-2.9
Ambulatory time before self-admin0.20.20.4-0.20.40.40.50.40.40.40.50.40.50.50.50.5-0.50.50.5-0.40.50.5-0.50.4-0.5-0.50.60.7
Ambulatory time after self-admin0.40.40.70.8-0.5-0.7-0.3-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.50.6-0.6-0.70.8-0.7-0.60.6-0.70.60.6-0.7-0.7
Bone: tissue strength0.60.61.20.9-1.0-0.8-1.1-0.8-0.8-0.8-0.6-0.8-0.8-0.8-0.7-0.70.8-0.8-0.70.6-0.7-0.70.7-0.70.70.7-0.5-0.5
Total heroin consumption3.23.85.1-2.21.91.92.11.91.91.91.81.91.91.92.02.0-1.91.91.9-2.31.92.0-2.01.7-1.9-2.01.91.9
Bone: trabecular number4.36.87.0-2.62.62.62.62.62.62.62.62.62.62.62.62.6-2.62.62.6-2.62.62.6-2.62.6-2.6-2.62.52.5
Bone: trabecular spacing2.93.84.72.0-2.2-2.1-2.1-2.0-2.0-2.0-1.9-2.0-2.0-2.0-2.0-1.92.0-2.0-1.91.7-1.9-1.91.9-1.91.91.9-1.7-1.6
Bone: trabecular thickness0.60.71.1-0.91.00.91.00.90.90.90.80.90.90.90.80.8-0.90.90.8-0.70.80.8-0.80.8-0.8-0.80.70.6
Bone: trabecular tissue density0.10.10.3-0.40.50.40.50.40.40.40.30.40.40.40.40.3-0.40.40.4-0.30.40.3-0.30.3-0.3-0.30.30.2
Water consumed over 24 hours1.92.22.8-1.71.51.51.51.51.51.51.51.51.51.51.51.5-1.51.51.5-1.51.51.5-1.51.5-1.5-1.51.41.4
Number of responses in last shaping day0.10.20.8-0.70.70.40.90.40.40.40.20.40.40.30.20.4-0.30.30.30.20.20.3-0.30.2-0.2-0.2-0.0-0.1