Hub : Genes

B4galt1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression B4galt1 0.08 0.07 3.2e-05 0.03 0.03 0.03 0.03 1.4e-04 2.4e-04 8.0e-04 3.1e-04
2 Liver gene expression B4galt1 0.07 0.07 1.8e-04 0.01 0.03 0.03 0.03 1.2e-02 5.6e-04 9.9e-05 3.6e-04
3 Adipose isoform ratio XM_039109259.2 0.05 0.03 5.5e-06 0.01 0.03 0.03 0.03 1.6e-02 1.0e-04 1.4e-04 3.8e-04
4 Adipose isoform ratio NM_053287.1 0.05 0.04 3.7e-06 0.01 0.04 0.04 0.03 1.2e-02 7.7e-05 8.8e-05 1.8e-04
5 Adipose alternative polyA XM_039109259.2 0.06 0.04 3.7e-07 0.01 0.04 0.04 0.04 1.8e-02 1.0e-05 1.8e-05 6.4e-05
6 Liver intron excision ratio chr5_60743801_60748924 0.13 0.07 8.4e-15 0.12 0.12 0.12 0.12 7.6e-13 9.1e-13 3.0e-13 7.4e-13
7 Liver alternative polyA NM_053287.1 0.2 0.09 0.0e+00 0.19 0.18 0.18 0.18 2.4e-20 9.2e-20 1.4e-19 9.2e-20
8 Liver isoform ratio XM_039109259.2 0.27 0.1 0.0e+00 0.27 0.27 0.27 0.26 1.2e-29 1.8e-29 1.5e-29 2.5e-29
9 Liver alternative polyA XM_039109259.2 0.24 0.1 0.0e+00 0.24 0.24 0.23 0.24 6.5e-26 7.5e-26 1.4e-25 6.2e-26
10 Liver intron excision ratio chr5_60738316_60748924 0.04 0.03 3.6e-04 0.02 0.02 0.01 0.02 3.0e-03 1.6e-03 7.0e-03 4.4e-03
11 Liver isoform ratio NM_053287.1 0.27 0.1 0.0e+00 0.27 0.27 0.27 0.27 7.7e-30 6.7e-30 8.6e-30 8.3e-30
12 Adipose alternative polyA NM_053287.1 0.06 0.04 3.0e-07 0.01 0.04 0.05 0.04 1.2e-02 1.1e-05 6.3e-06 4.1e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.81.42.7-1.3-0.1-1.61.6-1.60.9-0.90.9-1.21.41.0-1.0
Area under the delay curve0.40.61.01.0-0.01.0-1.00.9-0.50.5-0.50.6-0.9-0.70.8
BMI with tail0.31.25.7-2.4-0.7-1.41.3-1.30.2-0.20.2-0.61.10.60.8
BMI without tail0.21.05.3-2.3-1.0-1.31.2-1.2-0.10.1-0.1-0.20.90.3-0.2
Body weight0.62.612.9-3.6-2.8-0.90.7-0.6-1.51.6-1.60.90.1-0.80.3
Weight adjusted by age0.31.01.4-0.5-1.20.8-0.80.9-1.11.1-1.11.1-1.0-1.2-1.0
Bone surface0.10.31.1-1.0-0.7-0.60.6-0.6-0.10.1-0.1-0.10.40.1-0.8
Bone volume0.30.51.0-0.9-0.3-1.01.0-0.90.4-0.40.4-0.60.80.5-1.0
Breakpoint value in progressive ratio session3.05.47.90.1-1.12.8-2.82.8-2.32.3-2.32.6-2.7-2.51.8
Number of licking bursts0.82.57.0-2.6-1.0-2.32.2-2.10.6-0.60.6-1.21.70.9-1.0
Context. condit. distance diff. score0.10.10.30.50.4-0.10.1-0.10.4-0.40.4-0.30.20.30.1
Locomotion velocity, session 17.58.512.0-0.9-2.82.8-2.93.0-3.43.3-3.33.3-3.2-3.50.8
Locomotion distance, session 12.12.73.9-0.6-1.81.5-1.61.6-1.91.9-1.91.9-1.8-2.0-0.1
Locomotion velocity, session 20.60.71.9-1.4-0.4-1.31.2-1.20.4-0.40.4-0.71.00.6-0.3
Locomotion distance, session 20.81.23.2-1.7-1.80.2-0.30.4-1.21.2-1.20.9-0.7-1.2-0.4
Locomotion velocity, session 31.61.92.4-0.5-1.21.3-1.31.4-1.61.5-1.51.6-1.4-1.51.2
Locomotion distance, session 31.01.12.3-1.5-1.40.5-0.50.6-1.21.2-1.21.1-0.8-1.11.0
Stereotopy head waving bouts, day 30.50.61.0-0.5-0.80.7-0.70.7-0.90.9-0.90.8-0.8-1.00.3
Stereotopy head waving duration, day 30.00.00.1-0.3-0.2-0.10.1-0.1-0.10.1-0.1-0.0-0.0-0.1-0.3
Locomotion velocity, session 70.10.11.20.10.30.2-0.20.20.1-0.10.1-0.0-0.1-0.01.1
Locomotion distance, session 70.30.31.1-0.6-0.50.4-0.40.5-0.50.5-0.50.4-0.5-0.61.1
Stereotopy head waving bouts, day 70.50.62.3-1.5-1.2-0.70.6-0.6-0.40.4-0.40.10.3-0.2-1.3
Stereotopy head waving duration, day 70.40.51.6-1.2-0.9-0.80.8-0.7-0.10.1-0.1-0.20.50.0-1.3
Locomotion velocity, session 81.72.03.1-0.3-1.71.2-1.21.2-1.71.7-1.71.7-1.4-1.6-0.4
Locomotion distance, session 80.81.21.8-0.4-1.30.9-1.01.0-1.31.3-1.31.2-1.2-1.30.1
Degree of sensitization distance0.20.20.80.90.60.00.0-0.10.5-0.50.5-0.40.20.40.1
Degree of sensitization stereotypy0.60.72.3-1.3-0.9-1.00.9-0.9-0.00.0-0.0-0.30.60.2-1.5
Conditioned locomotion1.31.52.1-0.2-1.11.2-1.21.2-1.41.4-1.41.4-1.2-1.31.1
Cocaine response after cond. corrected1.62.33.40.8-0.81.9-1.91.9-1.51.5-1.51.7-1.8-1.60.8
Cocaine response after cond. not corrected1.92.84.00.6-1.21.9-1.92.0-1.81.8-1.81.8-2.0-1.90.6
Cocaine response before conditioning0.30.41.0-1.0-0.5-0.80.8-0.70.1-0.10.1-0.30.50.2-0.9
Saline control response1.01.43.9-1.7-2.00.2-0.20.3-1.41.4-1.41.1-0.7-1.2-0.8
Bone: connectivity density0.61.01.6-0.60.3-1.31.3-1.20.9-0.90.9-1.11.21.0-1.0
Bone: cortical apparent density0.81.31.70.21.0-1.21.2-1.21.3-1.31.3-1.31.31.3-0.3
Bone: cortical area1.72.85.5-1.8-0.2-2.42.3-2.31.2-1.21.2-1.62.01.5-1.4
Bone: cortical porosity0.20.20.60.40.4-0.30.3-0.30.5-0.50.5-0.50.40.4-0.8
Bone: cortical porosity0.10.10.7-0.2-0.3-0.20.2-0.2-0.00.0-0.0-0.00.1-0.0-0.8
Bone: cortical thickness2.43.96.2-0.80.7-2.52.5-2.51.9-1.91.9-2.12.32.0-1.7
Bone: cortical thickness0.91.11.40.50.9-0.91.0-1.01.2-1.21.2-1.21.01.1-1.0
Bone: cortical tissue density0.61.01.30.21.0-1.01.0-1.01.2-1.21.2-1.11.11.1-0.2
Condit. Reinf. active minus inactive responses0.10.10.5-0.7-0.4-0.30.3-0.2-0.20.2-0.20.00.1-0.1-0.1
Condit. Reinf. active-inactive response ratio0.20.20.91.00.80.2-0.20.20.4-0.40.4-0.20.00.30.1
Condit. Reinf. active responses0.50.63.5-1.9-1.0-1.00.9-0.8-0.20.2-0.2-0.10.60.1-0.5
Condit. Reinf. inactive responses0.81.03.9-2.0-1.0-1.41.3-1.30.1-0.10.1-0.51.00.4-0.8
Incentive salience index mean0.81.05.9-2.4-1.7-0.70.6-0.5-0.80.8-0.80.40.2-0.5-0.5
Condit. Reinf. lever presses2.33.516.9-4.1-3.4-0.80.7-0.5-1.71.7-1.71.0-0.2-1.3-1.1
Condit. Reinf. active minus inactive responses0.20.30.6-0.7-0.3-0.70.7-0.70.2-0.20.2-0.30.60.4-0.5
Condit. Reinf. active-inactive response ratio0.20.30.40.10.3-0.60.6-0.60.5-0.50.5-0.50.60.6-0.6
Condit. Reinf. active responses0.40.52.3-1.5-0.7-1.01.0-0.90.0-0.00.0-0.30.70.3-0.4
Condit. Reinf. inactive responses0.81.23.6-1.9-0.3-1.61.5-1.50.6-0.60.6-0.91.30.8-0.3
Condit. Reinf. lever presses1.42.03.7-1.80.1-1.91.9-1.91.0-1.01.0-1.31.71.30.2
Condit. Reinf. lever reinforcers received0.40.63.0-1.7-0.8-1.01.0-1.0-0.00.0-0.0-0.30.70.3-0.2
Conditioned reinforcement - actives0.10.31.2-1.10.1-0.60.6-0.60.2-0.20.2-0.30.60.51.1
Conditioned reinforcement - inactives0.10.21.6-1.3-0.20.1-0.10.1-0.20.3-0.30.3-0.1-0.20.6
Conditioned locomotion0.00.00.2-0.4-0.2-0.10.0-0.0-0.20.2-0.20.20.0-0.10.4
Patch foraging indifference point 0 sec2.15.97.8-1.2-2.52.3-2.32.4-2.82.7-2.72.6-2.6-2.81.6
Patch foraging indifference point AUC0.51.16.5-2.5-1.5-1.00.9-0.8-0.60.6-0.60.20.5-0.3-0.5
Delay disc. indifference point, 0s delay0.40.50.80.6-0.20.9-0.90.9-0.60.6-0.60.7-0.9-0.70.1
Delay disc. indifference point, 16s delay1.52.13.40.4-0.61.9-1.91.8-1.31.3-1.31.5-1.7-1.41.6
Delay disc. indifference point, 2s delay0.50.50.9-0.10.3-0.90.9-0.90.7-0.70.7-0.80.90.8-0.2
Delay disc. indifference point, 24s delay0.10.10.70.40.20.4-0.40.3-0.00.0-0.00.1-0.3-0.10.9
Delay disc. indifference point, 4s delay0.10.11.01.00.30.2-0.20.20.1-0.10.1-0.0-0.10.0-0.2
Delay disc. indifference point, 8s delay0.00.10.40.40.10.1-0.10.10.0-0.00.0-0.1-0.1-0.00.6
Indifference point function ln k0.20.62.11.40.41.1-1.01.0-0.20.2-0.20.4-0.8-0.40.6
Indifference point function log k0.20.62.11.40.41.1-1.01.0-0.20.2-0.20.4-0.8-0.40.6
Patch foraging total patch changes 0 sec1.64.87.1-1.6-2.71.8-1.81.9-2.62.5-2.52.3-2.2-2.61.2
Patch foraging total patch changes 12 sec0.20.31.8-1.3-0.8-0.30.3-0.2-0.40.4-0.40.20.1-0.20.8
Patch foraging total patch changes 18 sec0.20.50.8-0.6-0.70.5-0.60.6-0.70.7-0.70.7-0.7-0.80.9
Patch foraging total patch changes 24 sec0.20.82.8-1.7-1.60.0-0.10.2-1.01.0-1.00.7-0.5-0.9-0.2
Patch foraging total patch changes 6 sec1.83.04.9-2.2-2.20.9-1.01.1-2.02.0-2.01.7-1.4-1.91.6
Patch foraging time to switch 0 sec0.41.44.61.92.1-0.00.1-0.21.4-1.41.4-1.00.61.20.3
Patch foraging water rate 0 sec0.51.73.9-1.6-2.00.6-0.60.7-1.61.6-1.61.2-1.0-1.50.8
Patch foraging water rate 12 sec0.10.30.7-0.1-0.80.4-0.40.4-0.60.7-0.70.5-0.5-0.7-0.4
Patch foraging water rate 18 sec0.61.42.3-0.50.2-1.51.5-1.51.1-1.11.1-1.31.41.2-1.0
Patch foraging water rate 24 sec0.81.11.50.50.5-1.21.2-1.21.1-1.11.1-1.21.11.1-1.0
Patch foraging water rate 6 sec0.40.51.8-1.3-1.2-0.90.8-0.8-0.20.2-0.2-0.20.4-0.0-0.9
Seeking ratio, delayed vs. immediate footshock0.30.51.9-1.4-0.9-0.80.7-0.7-0.20.2-0.2-0.00.50.0-1.0
Distance traveled before self-admin0.71.57.2-2.7-2.2-0.70.6-0.5-1.11.1-1.10.6-0.0-0.8-0.5
Distance traveled after self-admin1.32.44.8-1.9-0.9-2.22.2-2.10.8-0.80.8-1.31.71.1-1.5
Extensor digitorum longus weight1.14.425.9-5.1-2.6-2.52.4-2.2-0.30.3-0.3-0.61.50.2-0.5
Bone: elastic displacement1.41.89.13.02.40.8-0.70.61.1-1.11.1-0.6-0.10.80.7
Bone: elastic work3.95.19.82.03.1-1.41.5-1.62.8-2.82.8-2.52.02.60.0
Bone: endosteal estimation0.51.23.4-1.8-1.60.3-0.30.4-1.31.3-1.31.0-0.6-1.00.7
Bone: endosteal perimeter0.51.32.9-1.7-1.70.3-0.40.5-1.41.4-1.41.1-0.7-1.10.8
Epididymis fat weight0.00.20.8-0.6-0.5-0.60.6-0.60.1-0.10.1-0.20.40.2-0.9
Delta time in closed arm before/after self-admin0.60.50.70.70.6-0.70.7-0.70.8-0.80.8-0.80.80.8-0.4
Delta time in open arm before/after self-admin0.50.63.8-0.6-0.20.6-0.60.6-0.50.5-0.50.6-0.6-0.52.0
Diff in mean of infusions in LGA sessions0.61.25.7-0.41.2-0.60.6-0.61.0-1.01.0-0.90.81.02.4
Delay discount exponential model param0.40.50.9-1.0-0.0-1.00.9-0.90.5-0.50.5-0.60.80.6-0.8
Extinction: sum of active levers before priming0.50.73.20.90.61.1-1.01.0-0.20.2-0.20.4-0.8-0.41.8
Active lever presses in extinction session 60.10.10.50.40.10.2-0.20.20.1-0.10.1-0.0-0.2-0.1-0.7
Bone: final force0.61.13.8-1.9-0.7-1.51.4-1.40.3-0.30.3-0.71.10.6-0.4
Bone: final moment0.81.32.9-1.7-0.3-1.61.6-1.50.7-0.60.6-1.01.30.9-0.4
Food consumed during 24 hour testing period0.40.82.4-1.2-1.50.1-0.10.2-1.11.1-1.10.8-0.5-0.80.0
Glucose0.30.52.5-1.6-1.2-0.40.3-0.3-0.60.6-0.60.30.0-0.4-0.0
Heart weight0.10.10.6-0.8-0.6-0.40.4-0.4-0.20.2-0.20.00.20.0-0.3
Delay discount hyperbolic model param0.40.50.8-0.90.0-0.90.9-0.90.5-0.50.5-0.60.80.6-0.8
Intermittent access intake day 1-15 change0.10.62.9-1.50.1-0.60.6-0.60.2-0.30.3-0.30.60.41.7
Intermittent access intake escalation0.10.82.4-1.40.4-0.90.9-0.80.5-0.60.6-0.60.90.71.6
Intermittent access intake escalation 21.42.43.5-1.70.7-1.91.8-1.81.3-1.41.4-1.61.81.51.1
Intermitt. access day 1 inactive lever presses0.00.41.2-1.1-0.90.3-0.30.3-0.80.7-0.70.6-0.5-0.80.2
Intermitt. access day 15 inactive lever presses0.00.10.7-0.8-0.4-0.10.0-0.0-0.20.1-0.10.1-0.1-0.2-0.6
Intermitt. access escalation Index0.00.10.4-0.7-0.3-0.20.1-0.1-0.10.1-0.10.10.1-0.1-0.3
Intermittent access day 1 total infusions0.30.81.71.30.61.3-1.31.2-0.40.5-0.50.9-1.0-0.60.5
Intermittent access day 15 total infusions0.20.63.1-0.70.8-0.50.5-0.50.6-0.60.6-0.50.70.71.8
Intermittent access terminal intake (last 3 days)0.40.73.5-1.60.1-0.70.6-0.60.3-0.30.3-0.30.60.51.9
Intermittent access total infusions0.20.22.1-0.80.2-0.0-0.00.0-0.10.1-0.10.20.10.11.5
Intermittent access day 1 locomotion0.40.72.21.50.41.2-1.21.1-0.40.4-0.40.8-0.9-0.6-0.5
Intermittent access day 15 total locomotion0.20.81.61.30.81.2-1.21.2-0.30.3-0.30.7-0.9-0.41.1
Intermittent access total locomotion0.30.41.51.21.20.2-0.20.10.6-0.50.5-0.20.10.50.4
Intermittent access standard deviation0.10.43.1-1.0-0.20.1-0.10.1-0.30.3-0.30.3-0.1-0.21.8
Left kidney weight0.43.67.8-2.0-2.80.9-1.01.1-2.42.4-2.42.1-1.4-2.0-0.1
Right kidney weight0.10.92.7-1.6-1.50.0-0.10.1-1.11.2-1.21.0-0.3-0.60.3
Cocaine induced anxiety0.10.32.5-0.3-0.8-0.30.3-0.2-0.30.3-0.30.1-0.0-0.3-1.6
Post-drug Anxiety0.70.82.9-1.3-1.7-0.30.2-0.2-0.90.9-0.90.5-0.3-0.8-1.4
Baseline Anxiety0.10.20.4-0.6-0.2-0.60.6-0.60.2-0.20.2-0.40.50.3-0.1
Tail length0.21.14.4-2.1-1.7-1.11.0-0.9-0.70.7-0.70.20.6-0.2-0.8
Length with tail0.73.38.9-2.3-3.00.4-0.50.6-2.32.3-2.31.9-1.1-1.8-0.1
Length without tail0.52.53.8-0.6-1.81.3-1.41.4-1.91.9-1.91.8-1.6-1.70.8
Times rat made contact with spout0.50.61.0-0.80.1-1.01.0-1.00.6-0.60.6-0.80.90.7-0.0
Lifetime Intake0.30.42.1-0.9-0.20.3-0.40.4-0.50.6-0.60.7-0.3-0.41.4
Liver weight, left0.20.30.4-0.4-0.60.3-0.30.4-0.70.7-0.70.6-0.5-0.60.2
Liver weight, right0.10.31.11.00.80.1-0.10.10.2-0.20.20.00.20.51.0
Locomotor activity0.00.00.3-0.20.30.1-0.10.10.2-0.20.2-0.10.00.10.6
Locomotor testing distance0.30.81.20.0-0.61.1-1.11.1-0.90.9-0.91.0-1.1-1.00.5
Locomotor testing rearing0.10.52.6-1.6-0.9-0.0-0.00.1-0.70.6-0.60.5-0.2-0.40.9
Locomotion in novel chamber0.60.86.20.6-0.1-0.60.6-0.60.5-0.50.5-0.60.50.4-2.5
Locomotion in novel chamber post-restriction0.72.23.9-1.1-0.0-2.02.0-2.01.1-1.11.1-1.41.81.4-1.5
Fecal boli incidents, locomotor time 10.20.62.81.01.10.8-0.80.70.2-0.20.20.1-0.40.11.7
Change in fecal boli incidents, locomotor task0.60.62.1-0.8-1.10.2-0.20.2-0.80.8-0.80.7-0.4-0.8-1.5
Time >=10cm from walls, locomotor time 10.30.40.5-0.5-0.60.6-0.60.6-0.70.7-0.70.7-0.6-0.70.1
Bouts of movement, locomotor time 10.20.31.90.50.60.2-0.20.10.3-0.30.3-0.20.10.41.4
Total resting periods, locomotor time 10.50.61.71.01.2-0.00.0-0.10.8-0.80.8-0.60.40.81.3
Rest time, locomotor task time 12.13.45.81.72.4-1.31.4-1.52.2-2.22.2-2.01.82.10.4
Distance moved, locomotor task time 10.92.54.5-2.1-2.10.9-1.01.1-1.81.8-1.81.6-1.4-1.80.6
Vertical activity count, locomotor time 10.43.05.4-1.5-2.31.2-1.21.3-2.12.1-2.11.9-1.6-2.0-0.2
Time >=10cm from walls, locomotor time 20.10.30.4-0.2-0.60.4-0.50.5-0.70.7-0.70.6-0.5-0.60.3
Bouts of movement, locomotor time 20.10.20.9-1.0-0.6-0.60.5-0.5-0.10.1-0.1-0.00.40.2-0.6
Total resting periods, locomotor time 20.00.20.5-0.7-0.2-0.50.5-0.50.0-0.10.1-0.10.40.3-0.7
Rest time, locomotor task time 20.40.71.81.01.3-0.40.4-0.41.0-1.01.0-0.70.60.9-0.5
Distance moved, locomotor task time 20.20.32.1-0.60.0-0.50.4-0.40.3-0.30.3-0.40.40.31.5
Vertical activity count, locomotor time 20.20.41.1-0.8-1.00.3-0.30.4-0.80.8-0.80.7-0.5-0.70.1
Light reinforcement 11.15.17.0-2.0-2.41.6-1.71.8-2.72.6-2.62.4-2.1-2.52.3
Light reinforcement 22.24.97.0-1.3-2.41.9-2.02.0-2.62.6-2.62.5-2.3-2.61.1
Bone: marrow area0.40.93.5-1.9-1.40.0-0.10.1-1.01.0-1.00.8-0.4-0.80.7
Bone: maximum diameter0.71.54.0-2.0-0.9-1.71.7-1.60.4-0.40.4-0.81.30.7-1.2
Bone: maximum force1.02.08.1-2.9-1.1-2.01.9-1.80.3-0.30.3-0.91.50.7-0.3
Bone: maximum moment1.12.16.4-2.5-0.7-2.12.0-1.90.6-0.60.6-1.11.61.0-0.4
Mean time between licks in bursts0.00.20.60.80.00.5-0.50.5-0.40.4-0.40.6-0.3-0.1-0.1
Mean num. licks in bursts0.30.83.31.81.21.2-1.11.00.1-0.10.10.4-0.7-0.11.0
Cd content in liver0.40.41.4-1.2-0.6-1.00.9-0.90.1-0.10.1-0.40.70.4-0.1
Co content in liver0.81.01.80.4-0.31.3-1.31.3-0.80.8-0.81.0-1.3-1.10.3
Cu content in liver0.30.42.21.51.00.3-0.30.20.5-0.50.5-0.3-0.10.30.2
Fe content in liver1.41.82.80.7-0.61.7-1.71.7-1.31.3-1.31.5-1.6-1.40.6
K content in liver0.50.50.80.3-0.20.9-0.90.9-0.60.6-0.60.7-0.9-0.70.5
Mg content in liver0.30.41.31.10.40.8-0.80.8-0.20.2-0.20.4-0.6-0.30.4
Mn content in liver1.41.63.3-1.3-0.2-1.81.8-1.70.8-0.80.8-1.21.51.1-0.7
Na content in liver0.20.21.11.00.80.1-0.10.10.4-0.40.4-0.20.10.40.4
Rb content in liver1.51.87.02.61.11.8-1.71.7-0.40.4-0.40.9-1.3-0.60.8
Se content in liver1.41.73.4-1.8-0.4-1.81.8-1.70.8-0.80.8-1.21.51.0-0.7
Sr content in liver0.30.20.5-0.6-0.1-0.70.7-0.70.3-0.30.3-0.50.60.4-0.3
Zn content in liver0.20.20.4-0.00.5-0.40.5-0.40.6-0.60.6-0.60.40.5-0.2
Bone: minimum diameter0.10.20.40.40.6-0.30.4-0.40.6-0.60.6-0.50.50.6-0.1
Time in familiar zone, hab. session 15.05.57.80.92.3-2.22.3-2.32.8-2.82.8-2.82.52.7-0.4
Time in novel zone, hab. session 15.46.08.70.8-1.42.9-3.03.0-2.62.6-2.62.9-2.9-2.60.6
Total zone transitions, hab. session 10.00.00.30.20.30.1-0.10.10.2-0.20.2-0.2-0.1-0.00.5
Total locomotion distance, hab. session 11.72.43.6-0.31.0-1.71.8-1.81.7-1.71.7-1.91.71.6-0.9
Locomotion velocity, hab. session 11.62.23.8-1.10.4-1.91.9-1.91.4-1.41.4-1.71.71.4-0.8
Time in familiar zone, hab. session 22.02.34.01.32.0-1.11.1-1.21.9-1.81.8-1.71.41.80.0
Time in novel zone, hab. session 22.93.24.50.4-1.22.1-2.12.1-1.91.9-1.92.0-2.1-2.00.2
Total zone transitions, hab. session 21.11.42.6-0.8-1.60.8-0.80.9-1.41.4-1.41.2-1.1-1.4-0.5
Total locomotion distance, hab. session 20.20.31.3-0.9-0.6-0.60.6-0.50.0-0.00.0-0.30.3-0.0-1.1
Locomotion velocity, hab. session 20.30.31.1-0.9-0.6-0.70.7-0.70.1-0.20.2-0.40.40.1-1.0
Novel to familiar place preference ratio2.02.75.11.60.12.3-2.22.2-1.31.3-1.31.7-1.9-1.40.9
Novelty place preference1.92.44.91.90.42.2-2.22.1-1.01.0-1.01.5-1.8-1.20.9
Time in novel zone, NPP test2.42.96.02.10.42.4-2.42.3-1.21.2-1.21.7-2.0-1.31.0
Total zone transitions, NPP test0.81.12.2-1.0-1.50.6-0.70.7-1.21.2-1.21.1-1.0-1.3-0.7
Total locomotion distance, NPP test0.50.82.4-1.5-1.5-0.0-0.00.1-0.90.9-0.90.6-0.4-0.9-0.6
Locomotion velocity, NPP test0.40.62.9-1.7-1.4-0.30.3-0.2-0.70.7-0.70.3-0.1-0.6-0.7
Intraocular pressure0.40.64.3-2.1-1.1-0.30.3-0.2-0.60.6-0.60.4-0.0-0.50.4
Delta distance traveled before/after self-admin0.40.51.7-0.10.0-0.60.6-0.60.6-0.60.6-0.70.70.6-1.3
Delta ambulatory time before/after self-admin0.30.52.00.20.2-0.50.5-0.50.7-0.70.7-0.70.60.6-1.4
Parametrial fat weight0.61.41.90.7-0.71.4-1.41.4-1.21.3-1.31.4-1.4-1.3-0.1
Pavlov. Cond. lever latency1.62.111.13.32.51.0-0.90.71.1-1.11.1-0.5-0.20.80.7
Pavlov. Cond. magazine entry latency0.10.20.5-0.7-0.7-0.0-0.00.0-0.50.5-0.50.3-0.2-0.4-0.4
Pavlov. Cond. change in total contacts1.01.03.7-1.9-1.70.0-0.10.1-1.21.2-1.20.9-0.5-0.9-0.1
Pavlov. Cond. index score0.70.84.6-2.2-1.5-0.80.7-0.7-0.50.5-0.50.10.3-0.3-0.6
Pavlov. Cond. latency score0.60.84.5-2.1-1.5-0.70.6-0.6-0.60.6-0.60.20.2-0.4-0.4
Pavlov. Cond. lever contacts1.51.89.7-3.1-2.3-1.00.9-0.8-0.91.0-1.00.40.3-0.6-0.7
Pavlov. Cond. magazine entry number0.10.10.60.80.50.4-0.40.30.1-0.10.10.0-0.20.00.6
Pavlov. Cond. intertrial magazine entries0.10.10.4-0.6-0.1-0.40.4-0.30.1-0.10.1-0.20.30.20.2
Pavlov. Cond. lever-magazine prob. diff.0.60.84.2-2.1-1.2-1.01.0-0.9-0.20.2-0.2-0.20.6-0.0-0.6
Pavlov. Cond. response bias0.91.15.4-2.3-1.8-0.70.6-0.5-0.90.9-0.90.40.1-0.5-0.6
Pavlov. Cond. lever latency1.41.93.61.6-0.21.9-1.91.8-1.11.1-1.11.4-1.7-1.3-0.5
Pavlov. Cond. magazine entry latency0.30.40.90.50.9-0.40.4-0.50.8-0.80.8-0.70.60.80.6
Pavlov. Cond. change in total contacts1.33.14.3-0.41.4-2.02.0-2.01.9-1.91.9-2.02.12.00.5
Pavlov. Cond. index score1.01.52.0-0.21.1-1.31.3-1.31.3-1.31.3-1.41.41.40.7
Pavlov. Cond. latency score1.21.92.6-0.31.1-1.51.6-1.61.5-1.51.5-1.61.61.60.6
Pavlov. Cond. lever contacts1.11.73.0-1.30.4-1.71.7-1.71.1-1.11.1-1.31.61.30.5
Pavlov. Cond. magazine entry number1.62.12.8-0.0-1.31.5-1.51.5-1.61.6-1.61.6-1.6-1.7-0.6
Pavlov. Cond. intertrial magazine entries0.10.31.1-0.6-0.8-0.10.1-0.0-0.50.5-0.50.4-0.1-0.3-1.1
Pavlov. Cond. lever-magazine prob. diff.1.21.82.4-0.11.2-1.41.4-1.51.5-1.51.5-1.51.51.50.7
Pavlov. Cond. response bias1.31.82.7-0.70.8-1.61.6-1.61.3-1.31.3-1.51.61.50.6
Time in closed arm before self-admin0.10.21.41.20.60.4-0.30.30.2-0.20.2-0.0-0.20.1-0.2
Time in closed arm after self-admin0.40.50.90.90.9-0.40.4-0.40.8-0.80.8-0.70.60.70.3
Time in open arm before self-admin0.91.12.5-1.4-1.60.4-0.50.5-1.21.2-1.21.0-0.7-1.1-0.7
Time in open arm after self-admin0.70.83.0-1.7-1.30.2-0.30.3-1.01.0-1.00.8-0.5-0.80.7
Bone: periosteal estimation0.30.84.2-2.0-1.1-1.11.1-1.0-0.10.1-0.1-0.20.70.2-0.4
Bone: periosteal perimeter0.30.51.4-1.2-1.20.1-0.20.2-0.90.9-0.90.7-0.4-0.70.1
Bone: post-yield work0.61.14.9-2.2-1.8-0.20.2-0.1-1.11.1-1.10.7-0.3-0.80.6
Progressive ratio test 1 active lever presses0.20.40.8-0.4-0.20.7-0.70.7-0.70.7-0.70.8-0.6-0.60.9
Progressive ratio test 1 breakpoint0.20.40.8-0.5-0.30.6-0.60.6-0.70.7-0.70.8-0.6-0.60.9
Progressive ratio test 1 inactive lever presses0.61.52.9-1.7-1.30.8-0.80.9-1.41.4-1.41.3-1.0-1.30.8
Progressive ratio test 2 active lever presses0.60.81.6-0.2-0.11.0-1.11.0-0.80.8-0.81.0-0.9-0.81.3
Progressive ratio test 2 breakpoint0.70.81.6-0.1-0.11.1-1.11.1-0.90.9-0.91.1-0.9-0.81.3
Progressive ratio test 2 inactive lever presses0.10.31.7-1.3-0.30.1-0.20.2-0.40.4-0.40.4-0.1-0.21.2
Incentive Sensitization - Responses0.10.40.9-0.4-0.10.6-0.60.6-0.60.6-0.60.7-0.5-0.50.9
Incentive Sensitization - Breakpoint0.20.41.1-0.3-0.10.7-0.70.7-0.60.6-0.60.8-0.6-0.51.0
Sum of active levers in priming session hrs 5-63.63.46.21.10.12.5-2.42.4-1.31.3-1.31.7-2.1-1.62.5
Progressive ratio0.10.30.50.7-0.20.7-0.70.7-0.50.5-0.50.6-0.7-0.6-0.3
Food seeking constrained by brief footshock2.93.610.8-3.3-3.2-0.30.2-0.1-2.02.0-2.01.5-0.6-1.6-2.2
Seeking ratio, punishment vs. effort0.51.15.8-2.4-1.5-1.01.0-0.9-0.50.5-0.50.10.5-0.1-0.9
Retroperitoneal fat weight0.20.74.22.01.20.2-0.10.10.7-0.70.7-0.40.20.6-1.1
Reaction time number correct0.10.50.7-0.1-0.50.8-0.80.8-0.80.8-0.80.9-0.8-0.70.5
Reaction time mean minus median1.06.28.9-0.12.2-2.62.7-2.72.8-2.82.8-2.82.93.00.2
Reaction time mean minus median AUC0.74.87.2-0.81.5-2.62.6-2.62.3-2.22.2-2.42.72.6-0.1
Reaction time num false alarms0.81.31.7-0.80.9-1.21.2-1.21.3-1.31.3-1.31.31.30.6
Reaction time num false alarms AUC0.30.72.3-1.50.1-1.00.9-0.90.6-0.60.6-0.80.90.70.9
Reaction time trials correct on left0.10.50.7-0.1-0.50.8-0.80.8-0.80.8-0.80.9-0.8-0.70.5
Reaction time trials on left0.10.50.70.0-0.40.8-0.80.8-0.70.7-0.70.8-0.8-0.70.6
Reaction time mean1.83.97.21.62.7-1.31.4-1.52.4-2.42.4-2.11.82.30.1
Reaction time mean AUC1.94.58.01.72.8-1.41.5-1.62.6-2.62.6-2.32.02.50.1
Median of all reaction times1.32.05.42.22.3-0.30.4-0.51.7-1.71.7-1.30.81.4-0.0
Reaction time omissions0.40.62.41.51.20.9-0.80.80.2-0.20.20.2-0.40.21.2
Reaction time false alarm rate0.81.11.4-0.70.8-1.11.1-1.11.1-1.11.1-1.21.21.10.6
Reaction time premature initiation rate1.11.75.42.02.30.3-0.30.21.2-1.21.2-0.80.30.92.1
Reaction time premature initiations0.41.24.61.81.80.8-0.70.60.6-0.60.6-0.2-0.20.42.1
Std. dev. reaction times1.75.58.20.62.5-2.12.2-2.32.8-2.82.8-2.72.62.90.4
Reaction time trials completed0.10.50.70.0-0.40.8-0.80.8-0.70.7-0.70.8-0.8-0.70.6
Reaction time trials AUC0.10.50.60.1-0.30.8-0.80.8-0.70.7-0.70.8-0.8-0.70.6
Run reversals in cocaine runway, females0.60.70.90.40.7-0.70.7-0.80.9-0.90.9-0.90.91.0-0.7
Run reversals in cocaine runway, males0.10.10.30.60.4-0.00.0-0.00.2-0.20.2-0.10.10.20.0
Latency to leave start box in cocaine runway0.10.20.5-0.6-0.4-0.70.7-0.70.0-0.00.0-0.30.50.20.0
Latency to leave start box in cocaine runway, F0.60.71.20.4-0.30.9-0.90.9-0.90.9-0.90.9-0.9-0.81.1
Latency to leave start box in cocaine runway, M1.11.02.6-1.6-1.1-1.41.3-1.20.0-0.00.0-0.50.90.2-1.5
Std. dev. time between licks in bursts0.10.20.60.70.70.2-0.10.10.3-0.30.3-0.10.10.30.5
Total sessions with >9 infusions0.40.51.2-1.0-0.50.4-0.40.4-0.70.8-0.80.8-0.4-0.51.1
Short access day 1 total inactive lever presses1.02.03.0-1.6-1.60.9-1.01.0-1.71.7-1.71.6-1.3-1.60.3
Short access day 10 total inactive lever presses0.00.32.1-1.5-0.7-0.30.3-0.2-0.20.2-0.2-0.00.1-0.20.3
Short access day 1 total infusions0.61.32.0-1.4-1.10.8-0.80.9-1.31.3-1.31.3-1.0-1.10.9
Short access day 10 total infusions0.61.01.5-0.0-0.31.2-1.21.2-1.01.1-1.11.2-1.1-1.01.1
Short access total infusions0.81.11.7-0.6-0.61.0-1.11.1-1.11.2-1.21.3-1.0-1.01.3
Short access day 1 locomotion0.40.71.61.10.41.3-1.21.2-0.40.4-0.40.8-1.0-0.60.3
Short access day 10 total locomotion0.20.92.71.61.4-0.30.3-0.41.2-1.11.1-0.90.61.1-0.0
Short access total locomotion0.20.30.80.90.60.6-0.60.6-0.00.1-0.10.3-0.4-0.10.8
One hour access (0.3 mA shock)0.40.52.4-0.90.00.6-0.60.6-0.50.5-0.50.6-0.5-0.51.6
Compulsive drug intake0.20.30.50.30.6-0.40.4-0.40.7-0.70.7-0.70.40.5-0.2
One hour access (shock baseline)0.61.52.2-0.8-0.61.2-1.31.3-1.31.3-1.31.5-1.2-1.31.3
Social response proportion0.50.73.61.90.70.5-0.40.30.3-0.30.3-0.1-0.20.1-1.8
Social responses0.10.20.7-0.8-0.6-0.20.2-0.2-0.40.4-0.40.30.0-0.2-0.4
Social time0.40.61.8-0.4-0.30.8-0.80.8-0.80.8-0.80.8-0.7-0.71.3
Soleus weight1.85.27.1-0.4-1.92.4-2.42.4-2.62.6-2.62.7-2.6-2.60.7
Bone: stiffness1.22.39.4-3.1-1.3-2.12.0-1.90.2-0.20.2-0.81.50.7-0.8
Tibialis anterior weight1.55.131.2-5.6-3.6-2.01.8-1.6-1.41.4-1.40.40.8-0.6-0.4
Time to tail flick, vehicle, before self-admin0.50.63.41.91.30.5-0.50.50.3-0.30.3-0.1-0.20.20.9
Time to tail flick, vehicle, after self-admin0.20.41.60.50.6-0.50.5-0.50.5-0.50.5-0.50.50.5-1.2
Time to tail flick, test, before self-admin0.10.10.8-0.1-0.2-0.50.4-0.40.00.0-0.0-0.10.30.1-0.9
Time to tail flick, test, after self-admin1.51.62.3-0.10.8-1.51.5-1.51.3-1.31.3-1.41.51.4-0.7
Delta time to tail flick, vehicle, before/after SA0.20.21.0-1.0-0.5-0.40.4-0.4-0.00.0-0.0-0.10.20.0-1.0
Delta time to tail flick, test, before/after SA0.40.50.80.50.9-0.40.4-0.50.9-0.90.9-0.80.60.80.3
Tibia length0.71.92.9-0.5-1.71.0-1.11.1-1.71.7-1.71.5-1.4-1.6-0.7
Ambulatory time before self-admin0.51.46.7-2.6-2.1-0.40.3-0.2-1.21.2-1.20.7-0.2-0.90.2
Ambulatory time after self-admin0.40.73.1-1.8-1.5-0.90.8-0.7-0.30.3-0.3-0.10.4-0.2-0.8
Bone: tissue strength0.10.10.2-0.5-0.0-0.40.4-0.40.2-0.20.2-0.30.30.3-0.1
Total heroin consumption0.91.11.90.60.11.4-1.41.4-0.80.8-0.81.1-1.2-0.91.3
Bone: trabecular number0.61.12.1-1.1-0.0-1.41.4-1.40.8-0.80.8-1.01.20.9-0.8
Bone: trabecular spacing0.30.40.5-0.20.3-0.70.7-0.70.6-0.60.6-0.70.70.6-0.7
Bone: trabecular thickness0.10.10.40.60.5-0.10.2-0.20.4-0.40.4-0.40.20.4-0.4
Bone: trabecular tissue density0.91.56.1-2.5-1.3-1.61.6-1.50.0-0.00.0-0.51.10.4-1.1
Water consumed over 24 hours0.20.52.2-1.5-1.0-0.80.7-0.7-0.20.2-0.2-0.10.40.0-0.5
Number of responses in last shaping day3.95.17.0-0.3-2.02.3-2.32.4-2.62.6-2.62.6-2.5-2.70.1