Hub : Genes

B4galt1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression B4galt1 0.08 0.07 3.2e-05 0.03 0.03 0.03 0.03 1.4e-04 2.4e-04 8.0e-04 3.5e-04
2 Liver gene expression B4galt1 0.07 0.07 1.8e-04 0.01 0.03 0.03 0.03 1.2e-02 5.6e-04 9.9e-05 3.5e-04
3 Adipose isoform ratio XM_039109259.2 0.05 0.03 5.5e-06 0.01 0.03 0.03 0.03 1.6e-02 1.0e-04 1.4e-04 3.9e-04
4 Adipose isoform ratio NM_053287.1 0.05 0.04 3.7e-06 0.01 0.04 0.04 0.03 1.2e-02 7.7e-05 8.5e-05 2.0e-04
5 Adipose alternative polyA XM_039109259.2 0.06 0.04 3.7e-07 0.01 0.04 0.04 0.04 1.8e-02 1.0e-05 1.8e-05 5.9e-05
6 Liver intron excision ratio chr5_60743801_60748924 0.13 0.07 8.4e-15 0.12 0.12 0.12 0.12 7.6e-13 9.1e-13 3.0e-13 7.5e-13
7 Liver alternative polyA NM_053287.1 0.2 0.09 0.0e+00 0.19 0.18 0.18 0.18 2.4e-20 9.2e-20 1.4e-19 9.8e-20
8 Liver isoform ratio XM_039109259.2 0.27 0.1 0.0e+00 0.27 0.27 0.27 0.26 1.2e-29 1.8e-29 1.5e-29 2.5e-29
9 Liver alternative polyA XM_039109259.2 0.24 0.1 0.0e+00 0.24 0.24 0.23 0.24 6.5e-26 7.5e-26 1.4e-25 6.2e-26
10 Liver intron excision ratio chr5_60738316_60748924 0.04 0.03 3.6e-04 0.02 0.02 0.01 0.02 3.0e-03 1.6e-03 7.0e-03 3.8e-03
11 Liver isoform ratio NM_053287.1 0.27 0.1 0.0e+00 0.27 0.27 0.27 0.27 7.7e-30 6.7e-30 8.7e-30 9.2e-30
12 Adipose alternative polyA NM_053287.1 0.06 0.04 3.0e-07 0.01 0.04 0.05 0.04 1.2e-02 1.1e-05 6.3e-06 4.9e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.81.42.71.30.1-1.61.6-1.6-0.90.9-0.9-1.11.41.01.0
Area under the delay curve0.50.61.0-1.00.01.0-1.00.90.5-0.50.50.6-0.9-0.7-0.8
BMI with tail0.31.25.72.40.7-1.41.3-1.3-0.20.2-0.2-0.51.10.6-0.8
BMI without tail0.31.05.32.31.0-1.31.2-1.20.1-0.10.1-0.20.90.30.2
Body weight0.62.612.93.62.8-0.90.7-0.61.5-1.61.60.90.1-0.8-0.3
Weight adjusted by age0.71.01.40.51.20.8-0.80.91.1-1.11.11.1-1.0-1.21.0
Bone surface0.20.31.11.00.7-0.60.6-0.60.1-0.10.1-0.10.40.10.8
Bone volume0.30.51.00.90.3-1.01.0-0.9-0.40.4-0.4-0.60.80.51.0
Breakpoint value in progressive ratio session4.55.47.9-0.11.12.8-2.82.82.3-2.32.32.6-2.7-2.5-1.8
Number of licking bursts1.52.57.02.61.0-2.32.2-2.1-0.60.6-0.6-1.21.70.91.0
Context. condit. distance diff. score0.10.10.3-0.5-0.4-0.10.1-0.1-0.40.4-0.4-0.30.20.3-0.1
Locomotion velocity, session 17.88.512.00.92.82.8-2.93.03.4-3.33.33.3-3.2-3.5-0.9
Locomotion distance, session 12.22.73.90.61.81.5-1.61.61.9-1.91.91.9-1.8-2.00.1
Locomotion velocity, session 20.60.71.91.40.4-1.31.2-1.2-0.40.4-0.4-0.71.00.60.3
Locomotion distance, session 20.81.23.21.71.80.2-0.30.41.2-1.21.20.9-0.7-1.20.4
Locomotion velocity, session 31.61.92.40.51.21.3-1.31.41.6-1.51.51.6-1.4-1.5-1.2
Locomotion distance, session 31.11.12.31.51.40.5-0.50.61.2-1.21.21.1-0.8-1.1-1.0
Stereotopy head waving bouts, day 30.50.61.00.50.80.7-0.70.70.9-0.90.90.8-0.8-1.0-0.3
Stereotopy head waving duration, day 30.00.00.10.30.2-0.10.1-0.10.1-0.10.1-0.0-0.0-0.10.3
Locomotion velocity, session 70.10.11.2-0.1-0.30.2-0.20.2-0.10.1-0.1-0.0-0.1-0.0-1.1
Locomotion distance, session 70.30.31.10.60.50.4-0.40.50.5-0.50.50.4-0.5-0.6-1.1
Stereotopy head waving bouts, day 70.50.62.31.51.2-0.70.6-0.60.4-0.40.40.10.3-0.21.3
Stereotopy head waving duration, day 70.40.51.61.20.9-0.80.8-0.70.1-0.10.1-0.20.50.01.3
Locomotion velocity, session 81.72.03.10.31.71.2-1.21.21.7-1.71.71.7-1.4-1.60.4
Locomotion distance, session 80.81.21.80.41.30.9-1.01.01.3-1.31.31.2-1.2-1.3-0.1
Degree of sensitization distance0.20.20.8-0.9-0.60.00.0-0.1-0.50.5-0.5-0.40.20.4-0.1
Degree of sensitization stereotypy0.60.72.31.30.9-1.00.9-0.90.0-0.00.0-0.30.60.21.5
Conditioned locomotion1.31.52.10.21.11.2-1.21.21.4-1.41.41.4-1.2-1.3-1.1
Cocaine response after cond. corrected1.92.33.4-0.80.81.9-1.91.91.5-1.51.51.7-1.8-1.6-0.8
Cocaine response after cond. not corrected2.42.84.0-0.61.11.9-1.92.01.8-1.81.81.8-2.0-1.9-0.6
Cocaine response before conditioning0.30.41.01.00.5-0.80.8-0.7-0.10.1-0.1-0.30.50.20.9
Saline control response1.01.43.91.72.00.2-0.20.31.4-1.41.41.1-0.7-1.20.8
Bone: connectivity density0.61.01.60.6-0.2-1.31.3-1.2-0.90.9-0.9-1.11.21.01.0
Bone: cortical apparent density0.91.31.7-0.2-1.0-1.21.2-1.2-1.31.3-1.3-1.31.31.30.3
Bone: cortical area1.82.85.51.80.2-2.42.3-2.3-1.21.2-1.2-1.62.01.51.4
Bone: cortical porosity0.20.20.6-0.4-0.4-0.30.3-0.3-0.50.5-0.5-0.50.40.40.8
Bone: cortical porosity0.10.10.70.20.3-0.20.2-0.20.0-0.00.0-0.00.1-0.00.8
Bone: cortical thickness2.43.96.20.8-0.7-2.52.5-2.5-1.91.9-1.9-2.12.32.01.7
Bone: cortical thickness0.91.11.4-0.5-0.9-0.91.0-1.0-1.21.2-1.2-1.21.01.11.0
Bone: cortical tissue density0.71.01.3-0.2-1.0-1.01.0-1.0-1.21.2-1.2-1.11.11.10.2
Condit. Reinf. active minus inactive responses0.10.10.50.70.4-0.30.3-0.20.2-0.20.20.10.1-0.10.1
Condit. Reinf. active-inactive response ratio0.20.20.9-1.0-0.80.2-0.20.2-0.40.4-0.4-0.20.00.3-0.1
Condit. Reinf. active responses0.50.63.51.91.1-1.00.9-0.80.2-0.20.2-0.10.60.10.5
Condit. Reinf. inactive responses0.81.03.92.01.0-1.41.3-1.3-0.10.1-0.1-0.51.00.40.8
Incentive salience index mean0.81.05.92.41.7-0.70.6-0.50.8-0.80.80.40.2-0.50.5
Condit. Reinf. lever presses2.53.516.94.13.4-0.80.7-0.51.7-1.71.71.0-0.2-1.31.1
Condit. Reinf. active minus inactive responses0.20.30.60.70.3-0.70.7-0.7-0.20.2-0.2-0.30.60.40.5
Condit. Reinf. active-inactive response ratio0.20.30.4-0.1-0.3-0.60.6-0.6-0.50.5-0.5-0.50.60.60.6
Condit. Reinf. active responses0.40.52.31.50.7-1.01.0-0.9-0.00.0-0.0-0.30.70.30.4
Condit. Reinf. inactive responses1.01.23.61.90.3-1.61.5-1.5-0.60.6-0.6-0.91.30.80.3
Condit. Reinf. lever presses1.42.03.71.8-0.1-1.91.9-1.9-1.01.0-1.0-1.31.71.3-0.2
Condit. Reinf. lever reinforcers received0.40.63.01.70.8-1.01.0-1.00.0-0.00.0-0.30.70.30.2
Conditioned reinforcement - actives0.20.31.21.1-0.1-0.60.6-0.6-0.20.2-0.2-0.30.60.5-1.1
Conditioned reinforcement - inactives0.10.21.61.30.20.1-0.10.10.2-0.30.30.3-0.1-0.2-0.6
Conditioned locomotion0.00.00.20.40.2-0.10.0-0.00.2-0.20.20.20.0-0.1-0.4
Patch foraging indifference point 0 sec3.25.97.81.22.52.3-2.32.42.8-2.72.72.6-2.6-2.8-1.6
Patch foraging indifference point AUC0.81.16.52.51.5-1.00.9-0.80.6-0.60.60.20.5-0.30.5
Delay disc. indifference point, 0s delay0.40.50.8-0.60.20.9-0.90.90.6-0.60.60.7-0.9-0.7-0.1
Delay disc. indifference point, 16s delay1.92.13.4-0.40.61.9-1.91.81.3-1.31.31.5-1.7-1.4-1.6
Delay disc. indifference point, 2s delay0.50.50.90.1-0.3-0.90.9-0.9-0.70.7-0.7-0.80.90.80.2
Delay disc. indifference point, 24s delay0.10.10.7-0.4-0.20.4-0.40.30.0-0.00.00.1-0.3-0.1-0.9
Delay disc. indifference point, 4s delay0.10.11.0-1.0-0.30.2-0.20.2-0.10.1-0.1-0.0-0.10.00.1
Delay disc. indifference point, 8s delay0.00.10.4-0.4-0.10.1-0.10.1-0.00.0-0.0-0.1-0.1-0.0-0.6
Indifference point function ln k0.30.62.1-1.4-0.41.1-1.01.00.2-0.20.20.4-0.8-0.4-0.6
Indifference point function log k0.30.62.1-1.4-0.41.1-1.01.00.2-0.20.20.4-0.8-0.4-0.6
Patch foraging total patch changes 0 sec2.64.87.11.62.71.8-1.81.92.6-2.52.52.3-2.2-2.6-1.2
Patch foraging total patch changes 12 sec0.20.31.81.30.8-0.30.3-0.20.4-0.40.40.20.1-0.2-0.8
Patch foraging total patch changes 18 sec0.30.50.80.60.70.5-0.60.60.7-0.70.70.7-0.7-0.8-0.9
Patch foraging total patch changes 24 sec0.50.82.81.71.60.0-0.10.21.0-1.01.00.7-0.5-0.90.2
Patch foraging total patch changes 6 sec2.03.04.92.22.20.9-1.01.12.0-2.02.01.7-1.4-1.9-1.6
Patch foraging time to switch 0 sec0.71.44.6-1.9-2.1-0.00.1-0.2-1.41.4-1.4-1.00.61.2-0.3
Patch foraging water rate 0 sec0.81.73.91.62.00.6-0.60.71.6-1.61.61.2-1.0-1.5-0.8
Patch foraging water rate 12 sec0.10.30.70.10.80.4-0.40.40.6-0.70.70.5-0.5-0.70.4
Patch foraging water rate 18 sec0.91.42.30.5-0.2-1.51.5-1.5-1.11.1-1.1-1.31.41.21.0
Patch foraging water rate 24 sec0.81.11.5-0.5-0.5-1.21.2-1.2-1.11.1-1.1-1.21.11.11.0
Patch foraging water rate 6 sec0.40.51.81.31.2-0.90.8-0.80.2-0.20.2-0.20.4-0.01.0
Seeking ratio, delayed vs. immediate footshock0.40.51.91.40.9-0.80.7-0.70.2-0.20.2-0.00.50.01.0
Distance traveled before self-admin1.21.57.22.72.2-0.70.6-0.51.1-1.11.10.6-0.0-0.80.5
Distance traveled after self-admin1.92.44.81.90.9-2.22.2-2.1-0.80.8-0.8-1.31.71.11.5
Extensor digitorum longus weight1.14.425.95.12.6-2.52.4-2.20.3-0.30.3-0.61.50.20.5
Bone: elastic displacement1.61.89.1-3.0-2.40.8-0.70.6-1.11.1-1.1-0.6-0.10.8-0.7
Bone: elastic work3.95.19.8-2.0-3.1-1.41.5-1.6-2.82.8-2.8-2.52.02.6-0.0
Bone: endosteal estimation0.51.23.41.81.60.3-0.30.41.3-1.31.31.0-0.6-1.0-0.7
Bone: endosteal perimeter0.61.32.91.71.70.3-0.40.51.4-1.41.41.1-0.7-1.1-0.8
Epididymis fat weight0.10.20.80.60.5-0.60.6-0.6-0.10.1-0.1-0.20.40.20.9
Delta time in closed arm before/after self-admin0.60.50.7-0.7-0.6-0.70.7-0.7-0.80.8-0.8-0.80.80.80.4
Delta time in open arm before/after self-admin0.60.63.80.60.20.6-0.60.60.5-0.50.50.6-0.6-0.5-2.0
Diff in mean of infusions in LGA sessions1.01.25.70.4-1.2-0.60.6-0.6-1.01.0-1.0-0.90.81.0-2.4
Delay discount exponential model param0.50.50.91.00.0-1.00.9-0.9-0.50.5-0.5-0.60.80.60.8
Extinction: sum of active levers before priming0.60.73.2-0.9-0.61.1-1.01.00.2-0.20.20.4-0.8-0.4-1.8
Active lever presses in extinction session 60.10.10.5-0.4-0.10.2-0.20.2-0.10.1-0.1-0.0-0.2-0.10.7
Bone: final force0.71.13.81.90.7-1.51.4-1.4-0.30.3-0.3-0.71.10.60.4
Bone: final moment0.81.32.91.70.3-1.61.6-1.5-0.70.6-0.6-0.91.30.90.4
Food consumed during 24 hour testing period0.60.82.41.21.50.1-0.10.21.1-1.11.10.8-0.5-0.8-0.0
Glucose0.30.52.51.61.2-0.40.3-0.30.6-0.60.60.30.0-0.40.0
Heart weight0.10.10.60.80.6-0.40.4-0.40.2-0.20.20.00.20.00.3
Delay discount hyperbolic model param0.40.50.80.9-0.0-0.90.9-0.9-0.50.5-0.5-0.60.80.60.8
Intermittent access intake day 1-15 change0.30.62.81.5-0.1-0.60.6-0.6-0.20.3-0.3-0.30.60.4-1.7
Intermittent access intake escalation0.40.82.41.4-0.3-0.90.9-0.8-0.50.6-0.6-0.60.90.7-1.6
Intermittent access intake escalation 22.12.43.51.7-0.7-1.91.8-1.8-1.31.4-1.4-1.61.81.5-1.1
Intermitt. access day 1 inactive lever presses0.10.41.21.10.90.3-0.30.30.8-0.70.70.6-0.5-0.8-0.2
Intermitt. access day 15 inactive lever presses0.10.10.70.80.4-0.10.0-0.00.2-0.10.10.1-0.1-0.20.6
Intermitt. access escalation Index0.00.10.40.70.3-0.20.1-0.10.1-0.10.10.10.1-0.10.3
Intermittent access day 1 total infusions0.50.81.7-1.3-0.61.3-1.31.20.4-0.50.50.9-1.0-0.6-0.5
Intermittent access day 15 total infusions0.40.63.10.7-0.8-0.50.5-0.5-0.60.6-0.6-0.50.70.7-1.8
Intermittent access terminal intake (last 3 days)0.50.73.51.6-0.1-0.70.6-0.6-0.30.3-0.3-0.30.60.5-1.9
Intermittent access total infusions0.20.22.10.8-0.2-0.0-0.00.00.1-0.10.10.20.10.1-1.5
Intermittent access day 1 locomotion0.60.72.2-1.5-0.41.2-1.21.10.4-0.40.40.8-0.9-0.60.5
Intermittent access day 15 total locomotion0.40.81.6-1.3-0.81.2-1.21.20.3-0.30.30.7-0.9-0.4-1.1
Intermittent access total locomotion0.30.41.5-1.2-1.20.2-0.20.1-0.60.5-0.5-0.20.10.5-0.4
Intermittent access standard deviation0.20.43.11.00.20.1-0.10.10.3-0.30.30.3-0.1-0.2-1.8
Left kidney weight0.83.67.82.02.80.9-1.01.12.4-2.42.42.1-1.4-2.00.1
Right kidney weight0.20.92.71.61.50.0-0.10.11.1-1.21.21.0-0.3-0.6-0.3
Cocaine induced anxiety0.20.32.50.30.8-0.30.3-0.20.3-0.30.30.1-0.0-0.31.6
Post-drug Anxiety0.80.82.91.31.7-0.30.2-0.20.9-0.90.90.5-0.3-0.81.4
Baseline Anxiety0.20.20.40.60.2-0.60.6-0.6-0.20.2-0.2-0.40.50.30.1
Tail length0.31.14.42.11.7-1.11.0-0.90.7-0.70.70.20.6-0.20.8
Length with tail0.73.38.92.33.00.4-0.50.62.3-2.32.31.9-1.1-1.80.1
Length without tail0.82.53.80.61.81.3-1.41.41.9-1.91.91.8-1.6-1.7-0.8
Times rat made contact with spout0.50.61.00.8-0.1-1.01.0-1.0-0.60.6-0.6-0.80.90.70.0
Lifetime Intake0.30.42.10.90.20.3-0.40.40.5-0.60.60.7-0.3-0.4-1.4
Liver weight, left0.20.30.40.40.60.3-0.30.40.7-0.70.70.6-0.5-0.6-0.2
Liver weight, right0.10.31.1-1.0-0.80.1-0.10.1-0.20.2-0.20.00.20.5-1.0
Locomotor activity0.00.00.30.2-0.30.1-0.10.1-0.20.2-0.2-0.10.00.1-0.6
Locomotor testing distance0.50.81.2-0.00.61.1-1.11.10.9-0.90.91.0-1.1-1.0-0.5
Locomotor testing rearing0.30.52.61.60.9-0.0-0.00.10.7-0.60.60.5-0.2-0.4-0.9
Locomotion in novel chamber0.60.86.2-0.60.1-0.60.6-0.6-0.50.5-0.5-0.60.50.42.5
Locomotion in novel chamber post-restriction1.32.23.91.10.0-2.02.0-2.0-1.11.1-1.1-1.41.81.41.5
Fecal boli incidents, locomotor time 10.40.62.8-1.0-1.10.8-0.80.7-0.20.2-0.20.1-0.40.1-1.7
Change in fecal boli incidents, locomotor task0.60.62.10.81.10.2-0.20.20.8-0.80.80.7-0.4-0.81.5
Time >=10cm from walls, locomotor time 10.40.40.50.50.60.6-0.60.60.7-0.70.70.7-0.6-0.7-0.1
Bouts of movement, locomotor time 10.20.31.9-0.5-0.60.2-0.20.1-0.30.3-0.3-0.20.10.4-1.4
Total resting periods, locomotor time 10.60.61.7-1.0-1.2-0.00.0-0.1-0.80.8-0.8-0.60.40.8-1.3
Rest time, locomotor task time 12.73.45.8-1.7-2.4-1.31.4-1.5-2.22.2-2.2-2.01.82.1-0.4
Distance moved, locomotor task time 11.72.54.52.12.10.9-1.01.11.8-1.81.81.6-1.4-1.8-0.6
Vertical activity count, locomotor time 11.23.05.41.52.31.2-1.21.32.1-2.12.11.9-1.6-2.00.2
Time >=10cm from walls, locomotor time 20.20.30.40.20.60.4-0.50.50.7-0.70.70.6-0.5-0.6-0.3
Bouts of movement, locomotor time 20.10.20.91.00.6-0.60.5-0.50.1-0.10.1-0.00.40.20.6
Total resting periods, locomotor time 20.10.20.50.70.2-0.50.5-0.5-0.00.1-0.1-0.10.40.30.7
Rest time, locomotor task time 20.50.71.8-1.0-1.3-0.40.4-0.4-1.01.0-1.0-0.70.60.90.5
Distance moved, locomotor task time 20.30.32.10.6-0.0-0.50.4-0.4-0.30.3-0.3-0.40.40.3-1.5
Vertical activity count, locomotor time 20.30.41.10.81.00.3-0.30.40.8-0.80.80.7-0.5-0.7-0.1
Light reinforcement 12.15.17.02.02.41.6-1.71.82.7-2.62.62.4-2.1-2.5-2.3
Light reinforcement 23.24.97.01.32.41.9-2.02.02.6-2.62.62.5-2.3-2.6-1.1
Bone: marrow area0.40.93.51.91.40.0-0.10.11.0-1.01.00.8-0.4-0.8-0.7
Bone: maximum diameter0.81.54.02.00.9-1.71.7-1.6-0.40.4-0.4-0.81.30.71.2
Bone: maximum force1.12.08.12.91.1-2.01.9-1.8-0.30.3-0.3-0.91.50.70.3
Bone: maximum moment1.22.16.42.50.7-2.12.0-1.9-0.60.6-0.6-1.11.61.00.4
Mean time between licks in bursts0.10.20.6-0.8-0.00.5-0.50.50.4-0.40.40.6-0.3-0.10.1
Mean num. licks in bursts0.50.83.3-1.8-1.21.2-1.11.0-0.10.1-0.10.4-0.7-0.1-1.0
Cd content in liver0.40.41.41.20.6-1.00.9-0.9-0.10.1-0.1-0.40.70.40.1
Co content in liver0.81.01.8-0.40.31.3-1.31.30.8-0.80.81.0-1.3-1.1-0.3
Cu content in liver0.30.42.2-1.5-1.00.3-0.30.2-0.50.5-0.5-0.3-0.10.3-0.2
Fe content in liver1.51.82.8-0.70.51.7-1.71.71.3-1.31.31.5-1.6-1.4-0.6
K content in liver0.50.50.8-0.30.20.9-0.90.90.6-0.60.60.7-0.9-0.7-0.5
Mg content in liver0.30.41.3-1.1-0.40.8-0.80.80.2-0.20.20.4-0.6-0.3-0.4
Mn content in liver1.41.63.31.30.2-1.81.8-1.7-0.80.8-0.8-1.21.51.10.7
Na content in liver0.20.21.1-1.0-0.80.1-0.10.1-0.40.4-0.4-0.20.10.4-0.4
Rb content in liver1.51.87.0-2.6-1.11.8-1.71.70.4-0.40.40.9-1.3-0.6-0.8
Se content in liver1.41.73.41.80.4-1.81.8-1.7-0.80.8-0.8-1.21.51.00.7
Sr content in liver0.30.20.50.60.1-0.70.7-0.7-0.30.3-0.3-0.50.60.40.3
Zn content in liver0.20.20.40.0-0.5-0.40.5-0.4-0.60.6-0.6-0.60.40.50.2
Bone: minimum diameter0.10.20.4-0.4-0.6-0.30.4-0.4-0.60.6-0.6-0.50.50.60.1
Time in familiar zone, hab. session 15.75.57.8-0.9-2.3-2.22.3-2.3-2.82.8-2.8-2.82.52.70.4
Time in novel zone, hab. session 16.06.08.7-0.81.42.9-3.03.02.6-2.62.62.9-2.9-2.6-0.6
Total zone transitions, hab. session 10.00.00.3-0.2-0.30.1-0.10.1-0.20.2-0.2-0.2-0.1-0.0-0.5
Total locomotion distance, hab. session 11.72.43.60.3-1.0-1.71.8-1.8-1.71.7-1.7-1.91.71.60.9
Locomotion velocity, hab. session 11.62.23.81.1-0.4-1.91.9-1.9-1.41.4-1.4-1.71.71.40.8
Time in familiar zone, hab. session 22.22.34.0-1.3-2.0-1.11.1-1.2-1.91.8-1.8-1.71.41.8-0.0
Time in novel zone, hab. session 23.13.24.5-0.41.22.1-2.12.11.9-1.91.92.0-2.1-2.0-0.2
Total zone transitions, hab. session 21.11.42.60.81.60.8-0.80.91.4-1.41.41.2-1.1-1.40.5
Total locomotion distance, hab. session 20.20.31.30.90.6-0.60.6-0.5-0.00.0-0.0-0.30.3-0.01.1
Locomotion velocity, hab. session 20.30.31.10.90.6-0.70.7-0.7-0.10.2-0.2-0.40.40.11.0
Novel to familiar place preference ratio2.42.75.1-1.6-0.12.3-2.22.21.3-1.31.31.7-1.9-1.4-1.0
Novelty place preference2.32.44.9-1.9-0.42.2-2.22.11.0-1.01.01.5-1.8-1.2-0.9
Time in novel zone, NPP test2.82.96.0-2.1-0.42.4-2.42.31.2-1.21.21.7-2.0-1.3-1.0
Total zone transitions, NPP test0.81.12.31.01.50.6-0.70.71.2-1.21.21.1-1.0-1.30.7
Total locomotion distance, NPP test0.60.82.41.51.5-0.0-0.00.10.9-0.90.90.6-0.4-0.90.6
Locomotion velocity, NPP test0.50.62.91.71.4-0.30.3-0.20.7-0.70.70.3-0.1-0.60.7
Intraocular pressure0.40.64.32.11.1-0.30.3-0.20.6-0.60.60.4-0.0-0.5-0.4
Delta distance traveled before/after self-admin0.40.51.70.1-0.0-0.60.6-0.6-0.60.6-0.6-0.70.70.61.3
Delta ambulatory time before/after self-admin0.40.52.0-0.2-0.2-0.50.5-0.5-0.70.7-0.7-0.70.60.61.4
Parametrial fat weight0.61.41.9-0.70.71.4-1.41.41.2-1.31.31.4-1.4-1.30.1
Pavlov. Cond. lever latency1.62.111.1-3.3-2.51.0-0.90.7-1.11.1-1.1-0.5-0.20.8-0.7
Pavlov. Cond. magazine entry latency0.10.20.50.70.7-0.0-0.00.00.5-0.50.50.3-0.2-0.40.4
Pavlov. Cond. change in total contacts1.01.03.71.91.70.0-0.10.11.2-1.21.20.9-0.5-0.90.1
Pavlov. Cond. index score0.70.84.62.21.5-0.80.7-0.70.5-0.50.50.10.3-0.30.7
Pavlov. Cond. latency score0.60.84.52.11.5-0.70.6-0.60.6-0.60.60.20.2-0.40.4
Pavlov. Cond. lever contacts1.51.89.73.12.3-1.00.9-0.80.9-1.01.00.40.3-0.60.7
Pavlov. Cond. magazine entry number0.10.10.6-0.8-0.50.4-0.40.3-0.10.1-0.10.0-0.20.0-0.6
Pavlov. Cond. intertrial magazine entries0.10.10.40.60.1-0.40.4-0.3-0.10.1-0.1-0.20.30.2-0.2
Pavlov. Cond. lever-magazine prob. diff.0.60.84.22.11.2-1.01.0-0.90.2-0.20.2-0.20.6-0.00.6
Pavlov. Cond. response bias0.91.15.42.31.8-0.70.6-0.50.9-0.90.90.40.1-0.50.6
Pavlov. Cond. lever latency1.41.93.6-1.60.21.9-1.91.81.1-1.11.11.3-1.7-1.30.5
Pavlov. Cond. magazine entry latency0.40.40.9-0.5-0.9-0.40.4-0.5-0.80.8-0.8-0.70.60.8-0.6
Pavlov. Cond. change in total contacts2.03.14.30.4-1.4-2.02.0-2.0-1.91.9-1.9-2.02.12.0-0.5
Pavlov. Cond. index score1.11.52.00.2-1.1-1.31.3-1.3-1.31.3-1.3-1.41.41.4-0.7
Pavlov. Cond. latency score1.41.92.60.3-1.1-1.51.6-1.6-1.51.5-1.5-1.61.61.6-0.6
Pavlov. Cond. lever contacts1.21.73.01.3-0.4-1.71.7-1.7-1.11.1-1.1-1.31.61.3-0.5
Pavlov. Cond. magazine entry number1.72.12.80.01.31.5-1.51.51.6-1.61.61.6-1.6-1.70.6
Pavlov. Cond. intertrial magazine entries0.20.31.10.60.8-0.10.1-0.00.5-0.50.50.4-0.1-0.31.1
Pavlov. Cond. lever-magazine prob. diff.1.31.82.40.1-1.2-1.41.4-1.5-1.51.5-1.5-1.51.51.5-0.7
Pavlov. Cond. response bias1.41.82.70.7-0.8-1.61.6-1.6-1.31.3-1.3-1.51.61.5-0.6
Time in closed arm before self-admin0.20.21.4-1.2-0.60.4-0.30.3-0.20.2-0.2-0.0-0.20.10.2
Time in closed arm after self-admin0.40.50.9-0.9-0.9-0.40.4-0.4-0.80.8-0.8-0.70.60.7-0.3
Time in open arm before self-admin1.01.12.51.41.60.4-0.50.51.2-1.21.21.0-0.7-1.10.7
Time in open arm after self-admin0.70.83.01.71.30.2-0.30.31.0-1.01.00.8-0.5-0.8-0.7
Bone: periosteal estimation0.40.84.22.01.1-1.11.1-1.00.1-0.10.1-0.20.70.20.4
Bone: periosteal perimeter0.30.51.41.21.20.1-0.20.20.9-0.90.90.7-0.4-0.7-0.0
Bone: post-yield work0.81.14.92.21.8-0.20.2-0.11.1-1.11.10.7-0.3-0.8-0.6
Progressive ratio test 1 active lever presses0.40.40.80.40.20.7-0.70.70.7-0.70.70.8-0.6-0.6-0.9
Progressive ratio test 1 breakpoint0.40.40.80.50.30.6-0.60.60.7-0.70.70.8-0.6-0.6-0.9
Progressive ratio test 1 inactive lever presses1.01.52.91.71.30.8-0.80.91.4-1.41.41.3-1.0-1.3-0.8
Progressive ratio test 2 active lever presses0.70.81.60.20.11.0-1.11.00.8-0.80.81.0-0.9-0.8-1.3
Progressive ratio test 2 breakpoint0.70.81.60.10.11.1-1.11.10.9-0.90.91.1-0.9-0.8-1.3
Progressive ratio test 2 inactive lever presses0.20.31.71.30.30.1-0.20.20.4-0.40.40.4-0.1-0.2-1.2
Incentive Sensitization - Responses0.30.40.90.40.20.6-0.60.60.6-0.60.60.7-0.5-0.5-0.9
Incentive Sensitization - Breakpoint0.30.41.10.30.10.7-0.70.70.6-0.60.60.8-0.6-0.5-1.0
Sum of active levers in priming session hrs 5-63.63.46.3-1.1-0.12.5-2.42.41.3-1.31.31.7-2.1-1.6-2.5
Progressive ratio0.20.30.5-0.70.20.7-0.70.70.5-0.50.50.6-0.7-0.60.3
Food seeking constrained by brief footshock2.93.610.83.33.2-0.30.2-0.12.0-2.02.01.5-0.6-1.62.2
Seeking ratio, punishment vs. effort0.71.15.82.41.5-1.01.0-0.90.5-0.50.50.10.5-0.10.9
Retroperitoneal fat weight0.20.74.2-2.0-1.20.2-0.10.1-0.70.7-0.7-0.40.20.61.1
Reaction time number correct0.30.50.70.10.50.8-0.80.80.8-0.80.80.9-0.8-0.7-0.5
Reaction time mean minus median2.56.28.90.1-2.2-2.62.7-2.7-2.82.8-2.8-2.82.93.0-0.2
Reaction time mean minus median AUC1.94.87.20.8-1.5-2.62.6-2.6-2.32.2-2.2-2.42.72.60.1
Reaction time num false alarms0.91.31.70.8-0.9-1.21.2-1.2-1.31.3-1.3-1.31.31.3-0.6
Reaction time num false alarms AUC0.50.72.31.5-0.1-1.00.9-0.9-0.60.6-0.6-0.80.90.7-0.9
Reaction time trials correct on left0.30.50.70.10.50.8-0.80.80.8-0.80.80.9-0.8-0.7-0.5
Reaction time trials on left0.30.50.7-0.00.40.8-0.80.80.7-0.70.70.8-0.8-0.7-0.6
Reaction time mean2.43.97.2-1.6-2.7-1.31.4-1.5-2.42.4-2.4-2.21.82.3-0.1
Reaction time mean AUC2.84.58.0-1.7-2.8-1.41.5-1.6-2.62.6-2.6-2.32.02.5-0.1
Median of all reaction times1.42.05.4-2.2-2.3-0.30.4-0.5-1.71.7-1.7-1.30.81.40.0
Reaction time omissions0.40.62.4-1.5-1.20.9-0.80.8-0.20.2-0.20.2-0.40.2-1.2
Reaction time false alarm rate0.81.11.40.7-0.8-1.11.1-1.1-1.11.1-1.1-1.21.21.1-0.5
Reaction time premature initiation rate1.21.75.4-2.0-2.30.3-0.30.2-1.21.2-1.2-0.80.30.9-2.1
Reaction time premature initiations0.71.24.6-1.8-1.80.8-0.70.6-0.60.6-0.6-0.2-0.20.4-2.1
Std. dev. reaction times3.05.58.2-0.6-2.5-2.12.2-2.3-2.82.8-2.8-2.72.62.9-0.4
Reaction time trials completed0.30.50.7-0.00.40.8-0.80.80.7-0.70.70.8-0.8-0.7-0.6
Reaction time trials AUC0.20.50.6-0.10.30.8-0.80.80.7-0.70.70.8-0.8-0.7-0.6
Run reversals in cocaine runway, females0.70.70.9-0.4-0.7-0.70.7-0.8-0.90.9-0.9-0.90.91.00.7
Run reversals in cocaine runway, males0.10.10.3-0.6-0.4-0.00.0-0.0-0.20.2-0.2-0.10.10.2-0.0
Latency to leave start box in cocaine runway0.20.20.50.60.4-0.70.7-0.7-0.00.0-0.0-0.30.50.2-0.0
Latency to leave start box in cocaine runway, F0.60.71.2-0.40.30.9-0.90.90.9-0.90.90.9-0.9-0.8-1.1
Latency to leave start box in cocaine runway, M1.11.02.61.61.1-1.41.3-1.2-0.00.0-0.0-0.50.90.21.5
Std. dev. time between licks in bursts0.10.20.6-0.7-0.70.2-0.10.1-0.30.3-0.3-0.10.10.3-0.5
Total sessions with >9 infusions0.40.51.21.00.50.4-0.40.40.7-0.80.80.8-0.4-0.5-1.1
Short access day 1 total inactive lever presses1.52.03.01.61.60.9-1.01.01.7-1.71.71.6-1.3-1.6-0.3
Short access day 10 total inactive lever presses0.10.32.11.50.7-0.30.3-0.20.2-0.20.2-0.00.1-0.2-0.3
Short access day 1 total infusions1.01.32.01.41.10.8-0.80.91.3-1.31.31.3-1.0-1.1-0.9
Short access day 10 total infusions0.81.01.50.00.31.2-1.21.21.0-1.11.11.2-1.1-1.0-1.1
Short access total infusions0.91.11.70.60.61.0-1.11.11.1-1.21.21.3-1.0-1.0-1.3
Short access day 1 locomotion0.60.71.6-1.1-0.41.3-1.21.20.4-0.40.40.8-1.0-0.6-0.3
Short access day 10 total locomotion0.50.92.7-1.6-1.4-0.30.3-0.4-1.21.1-1.1-0.90.61.10.0
Short access total locomotion0.20.30.8-0.9-0.60.6-0.60.60.0-0.10.10.3-0.4-0.1-0.8
One hour access (0.3 mA shock)0.40.52.40.9-0.10.6-0.60.60.5-0.50.50.6-0.5-0.5-1.6
Compulsive drug intake0.20.30.5-0.3-0.6-0.40.4-0.4-0.70.7-0.7-0.70.40.50.2
One hour access (shock baseline)1.01.52.20.80.61.2-1.31.31.3-1.31.31.5-1.2-1.3-1.3
Social response proportion0.60.73.6-1.9-0.70.5-0.40.3-0.30.3-0.3-0.1-0.20.11.8
Social responses0.10.20.70.80.6-0.20.2-0.20.4-0.40.40.30.0-0.20.4
Social time0.40.61.80.40.30.8-0.80.80.7-0.80.80.8-0.7-0.7-1.3
Soleus weight1.85.27.10.41.92.4-2.42.42.6-2.62.62.7-2.6-2.6-0.7
Bone: stiffness1.42.39.43.11.3-2.12.0-1.9-0.20.2-0.2-0.81.50.70.8
Tibialis anterior weight1.55.131.25.63.6-2.01.8-1.61.4-1.41.40.40.8-0.60.4
Time to tail flick, vehicle, before self-admin0.60.63.4-1.9-1.30.5-0.50.5-0.30.3-0.3-0.1-0.20.2-0.9
Time to tail flick, vehicle, after self-admin0.30.41.5-0.5-0.6-0.50.5-0.5-0.50.5-0.5-0.50.50.51.2
Time to tail flick, test, before self-admin0.10.10.80.10.2-0.50.4-0.4-0.0-0.00.0-0.10.30.10.9
Time to tail flick, test, after self-admin1.51.62.30.1-0.8-1.51.5-1.5-1.31.3-1.3-1.41.51.40.7
Delta time to tail flick, vehicle, before/after SA0.20.21.01.00.5-0.40.4-0.40.0-0.00.0-0.10.20.01.0
Delta time to tail flick, test, before/after SA0.50.50.8-0.5-0.9-0.40.4-0.5-0.90.9-0.9-0.80.60.8-0.3
Tibia length0.71.92.90.51.71.0-1.11.11.7-1.71.71.5-1.4-1.60.7
Ambulatory time before self-admin1.01.46.72.62.1-0.40.3-0.21.2-1.21.20.7-0.2-0.9-0.2
Ambulatory time after self-admin0.60.73.11.81.5-0.90.8-0.70.3-0.30.3-0.10.4-0.20.8
Bone: tissue strength0.10.10.20.50.0-0.40.4-0.4-0.20.2-0.2-0.30.30.30.1
Total heroin consumption0.91.11.9-0.6-0.11.4-1.41.40.8-0.80.81.1-1.2-0.9-1.3
Bone: trabecular number0.71.12.11.10.1-1.41.4-1.4-0.80.8-0.8-1.01.20.90.8
Bone: trabecular spacing0.30.40.50.2-0.3-0.70.7-0.7-0.60.6-0.6-0.70.70.60.7
Bone: trabecular thickness0.10.10.4-0.6-0.5-0.10.2-0.2-0.40.4-0.4-0.40.20.40.4
Bone: trabecular tissue density1.01.56.12.51.3-1.61.6-1.5-0.00.0-0.0-0.51.10.41.1
Water consumed over 24 hours0.30.52.21.51.0-0.80.7-0.70.2-0.20.2-0.10.40.00.5
Number of responses in last shaping day4.65.17.00.32.02.3-2.32.42.6-2.62.62.6-2.5-2.7-0.1