Hub : Genes

B3gnt2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA mRNA stability B3gnt2 0.18 0.08 1.6e-05 0 0.09 0.05 0.05 2.9e-01 2.7e-05 9.4e-04 1.7e-03
2 Adipose mRNA stability B3gnt2 0.07 0.04 9.5e-08 0.04 0.06 0.04 0.04 1.2e-05 6.4e-07 1.7e-05 1.9e-05
3 PL mRNA stability B3gnt2 0.1 0.04 1.1e-16 0.14 0.14 0.12 0.14 1.9e-15 1.6e-15 7.2e-13 1.3e-15
4 Liver gene expression B3gnt2 0.05 0.03 5.3e-10 0.09 0.09 0.09 0.09 1.4e-10 1.0e-09 5.6e-10 3.7e-10
5 NAcc isoform ratio XM_039092089.1 0.06 0.04 4.9e-04 0 0.03 0.03 0.02 6.9e-02 2.6e-04 7.2e-05 4.1e-03
6 Adipose isoform ratio XM_006251556.4 0.04 0.03 7.7e-03 0.01 0 0.01 0.01 1.8e-02 7.2e-02 8.6e-03 4.3e-02
7 Brain mRNA stability B3gnt2 0.06 0.03 1.1e-07 0.07 0.08 0.06 0.07 5.5e-07 9.6e-08 2.4e-06 5.8e-07
8 OFC mRNA stability B3gnt2 0.16 0.09 4.7e-03 0.03 0.03 0 0 6.7e-02 8.0e-02 2.5e-01 2.4e-01
9 Liver mRNA stability B3gnt2 0.07 0.03 5.1e-12 0.1 0.11 0.11 0.1 1.2e-10 7.1e-12 9.3e-12 7.2e-11
10 NAcc mRNA stability B3gnt2 0.05 0.03 4.1e-07 0.05 0.05 0.04 0.06 1.5e-06 7.3e-07 1.2e-05 3.7e-07
11 Brain gene expression B3gnt2 0.05 0.03 1.5e-04 0.04 0.03 0.03 0.03 1.9e-04 5.0e-04 2.0e-03 1.1e-03
12 Adipose gene expression B3gnt2 0.05 0.06 2.3e-03 0.01 0.01 0.01 0.01 1.2e-02 3.6e-02 3.5e-02 3.2e-02
13 NAcc isoform ratio XM_006251554.4 0.07 0.05 3.9e-03 0.02 0.01 0.01 0.01 3.3e-03 1.5e-02 5.3e-02 4.2e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density0.71.21.9-0.71.2-1.31.40.80.8-1.31.1-1.2-1.3-1.4-0.7-0.7
Area under the delay curve1.41.43.11.6-1.51.4-1.2-1.8-0.11.4-1.01.41.11.00.40.4
BMI with tail0.51.75.61.4-1.61.2-1.2-2.4-1.01.3-1.30.91.10.91.01.0
BMI without tail1.22.55.40.5-1.61.5-1.7-1.5-2.31.6-1.51.31.31.22.02.0
Body weight2.18.615.33.5-3.93.1-3.1-3.7-1.63.2-3.12.93.02.71.51.5
Weight adjusted by age0.10.10.9-0.2-0.1-0.20.1-0.9-0.1-0.2-0.0-0.30.1-0.1-0.5-0.5
Bone surface0.50.91.8-0.20.6-1.21.30.40.5-1.11.1-1.1-1.3-1.3-0.6-0.6
Bone volume0.40.61.3-0.40.6-1.11.10.10.2-0.90.8-1.1-1.1-1.1-0.3-0.3
Breakpoint value in progressive ratio session1.61.75.32.1-1.51.3-1.0-2.30.51.3-1.10.91.01.20.80.8
Number of licking bursts0.20.20.4-0.4-0.20.4-0.4-0.4-0.50.5-0.50.30.50.50.70.7
Context. condit. distance diff. score0.60.71.5-0.91.2-0.90.90.81.0-0.90.8-0.9-0.9-1.0-0.2-0.2
Locomotion velocity, session 10.70.73.41.8-1.0-0.30.5-0.50.20.00.00.1-0.3-0.2-1.5-1.5
Locomotion distance, session 10.81.03.51.6-0.5-0.50.6-0.21.5-0.10.3-0.1-0.3-0.3-1.9-1.9
Locomotion velocity, session 20.50.63.10.3-0.3-0.70.7-0.00.2-0.30.5-0.00.00.1-1.8-1.8
Locomotion distance, session 21.62.35.50.30.4-1.81.8-0.11.3-1.31.7-1.3-1.5-1.4-2.3-2.3
Locomotion velocity, session 30.60.72.51.6-1.10.10.0-0.10.40.4-0.30.80.40.4-1.5-1.5
Locomotion distance, session 31.21.35.62.4-1.50.9-0.9-0.21.01.0-0.81.20.70.8-1.0-1.0
Stereotopy head waving bouts, day 30.60.71.4-0.30.7-0.90.90.60.3-0.90.9-1.0-0.9-0.9-1.2-1.2
Stereotopy head waving duration, day 30.20.20.4-0.60.5-0.40.40.5-0.3-0.40.3-0.4-0.2-0.3-0.5-0.5
Locomotion velocity, session 70.50.51.5-0.30.4-0.80.80.80.4-0.60.7-0.3-0.5-0.6-1.2-1.2
Locomotion distance, session 71.41.73.1-0.81.0-1.51.40.91.0-1.31.5-1.2-1.2-1.2-1.8-1.8
Stereotopy head waving bouts, day 70.60.61.00.4-0.41.0-1.0-0.3-0.20.9-1.00.80.90.91.01.0
Stereotopy head waving duration, day 71.72.02.81.5-1.51.7-1.7-1.1-0.61.6-1.61.51.51.51.21.2
Locomotion velocity, session 80.30.31.40.3-0.3-0.70.8-1.20.3-0.20.5-0.4-0.2-0.2-0.8-0.8
Locomotion distance, session 80.71.01.90.20.3-1.21.4-0.31.2-0.81.0-0.7-0.8-0.9-1.4-1.4
Degree of sensitization distance4.64.67.3-2.72.7-2.52.51.11.2-2.42.5-2.7-2.2-2.3-0.9-0.9
Degree of sensitization stereotypy2.93.24.41.5-1.62.1-2.1-1.1-0.62.0-2.11.92.02.01.71.7
Conditioned locomotion1.01.14.10.70.5-0.90.9-0.22.0-0.80.8-0.7-0.8-0.6-1.7-1.7
Cocaine response after cond. corrected1.01.13.71.8-0.2-0.50.4-0.91.9-0.40.5-0.7-0.8-0.8-1.4-1.4
Cocaine response after cond. not corrected0.30.41.81.3-0.5-0.0-0.1-0.60.8-0.10.1-0.2-0.3-0.3-0.9-0.9
Cocaine response before conditioning1.41.76.1-1.0-0.81.2-1.20.3-2.51.0-1.21.31.41.41.31.3
Saline control response2.22.910.50.60.8-1.31.30.42.4-1.21.3-1.0-1.0-1.0-3.2-3.2
Bone: connectivity density1.01.62.3-1.31.5-1.41.51.50.7-1.41.3-1.2-1.4-1.3-0.6-0.6
Bone: cortical apparent density0.50.61.50.6-0.50.8-0.7-0.30.20.9-1.01.21.21.1-0.3-0.3
Bone: cortical area1.62.45.01.2-2.01.5-1.6-1.3-2.21.4-1.41.61.21.21.41.4
Bone: cortical porosity0.10.21.2-0.2-0.50.1-0.20.2-1.10.1-0.10.30.20.2-0.4-0.4
Bone: cortical porosity0.10.21.00.1-0.60.2-0.3-0.0-1.00.2-0.20.30.20.2-0.3-0.3
Bone: cortical thickness1.52.53.51.2-1.91.7-1.8-1.3-1.61.6-1.61.91.71.61.31.3
Bone: cortical thickness0.10.10.40.6-0.1-0.10.00.30.2-0.1-0.0-0.0-0.4-0.4-0.1-0.1
Bone: cortical tissue density0.40.51.30.5-0.40.8-0.6-0.30.30.9-0.91.11.21.1-0.3-0.3
Condit. Reinf. active minus inactive responses0.40.51.10.2-0.60.7-0.60.9-1.10.6-0.61.00.60.70.40.4
Condit. Reinf. active-inactive response ratio0.30.30.60.1-0.30.5-0.50.7-0.80.5-0.40.60.40.50.80.8
Condit. Reinf. active responses0.40.51.20.9-0.90.7-0.7-0.1-0.40.9-0.81.10.90.9-0.1-0.1
Condit. Reinf. inactive responses0.70.92.21.3-1.10.7-0.7-1.50.41.0-1.00.91.10.9-0.1-0.1
Incentive salience index mean1.11.42.91.7-1.61.2-1.2-0.2-0.61.3-1.21.61.21.30.10.1
Condit. Reinf. lever presses1.41.87.32.7-2.01.0-1.0-1.20.31.3-1.11.51.11.2-0.7-0.7
Condit. Reinf. active minus inactive responses0.40.52.31.5-0.80.5-0.5-1.21.20.7-0.40.20.20.30.10.1
Condit. Reinf. active-inactive response ratio0.60.71.41.2-0.70.8-0.9-0.80.70.9-0.70.40.40.41.11.1
Condit. Reinf. active responses0.20.21.00.7-0.2-0.20.2-0.21.00.00.3-0.2-0.2-0.1-0.8-0.8
Condit. Reinf. inactive responses2.12.66.8-0.61.0-1.71.71.50.7-1.61.6-1.2-1.4-1.4-2.6-2.6
Condit. Reinf. lever presses0.30.41.10.9-0.50.3-0.4-0.20.60.3-0.20.50.30.3-1.1-1.1
Condit. Reinf. lever reinforcers received0.10.20.60.3-0.0-0.30.3-0.00.8-0.10.4-0.3-0.3-0.2-0.8-0.8
Conditioned reinforcement - actives0.70.72.70.5-0.90.8-1.1-1.7-0.30.9-0.60.40.91.00.20.2
Conditioned reinforcement - inactives2.42.74.01.2-1.81.8-1.7-1.5-1.41.8-2.01.81.81.51.51.5
Conditioned locomotion0.40.51.1-0.80.9-0.50.40.30.5-0.80.7-0.8-0.6-0.4-1.0-1.0
Patch foraging indifference point 0 sec0.10.10.5-0.70.4-0.10.00.10.0-0.30.6-0.4-0.4-0.3-0.0-0.0
Patch foraging indifference point AUC0.20.31.30.7-0.0-0.10.1-0.31.10.10.20.00.10.1-0.9-0.9
Delay disc. indifference point, 0s delay2.83.14.92.2-2.02.0-1.8-2.1-0.32.1-1.71.91.71.41.51.5
Delay disc. indifference point, 16s delay0.50.51.81.4-0.80.6-0.5-0.90.30.7-0.50.70.60.6-0.2-0.2
Delay disc. indifference point, 2s delay2.32.64.22.0-2.01.7-1.5-1.90.02.0-1.71.81.71.50.80.8
Delay disc. indifference point, 24s delay0.50.50.7-0.90.8-0.70.60.80.1-0.80.8-0.7-0.7-0.6-0.8-0.8
Delay disc. indifference point, 4s delay1.11.22.71.0-1.41.3-1.2-1.6-0.61.3-0.91.21.00.80.70.7
Delay disc. indifference point, 8s delay1.01.12.91.7-1.51.1-0.9-1.70.21.0-0.71.00.90.7-0.2-0.2
Indifference point function ln k0.20.21.0-0.60.1-0.30.30.4-1.0-0.40.3-0.3-0.4-0.40.40.4
Indifference point function log k0.20.21.0-0.60.1-0.30.30.4-1.0-0.40.3-0.3-0.4-0.40.40.4
Patch foraging total patch changes 0 sec0.20.30.8-0.80.7-0.40.30.10.3-0.50.9-0.7-0.6-0.6-0.2-0.2
Patch foraging total patch changes 12 sec0.10.21.2-0.30.3-0.20.1-1.10.6-0.10.5-0.5-0.2-0.10.20.2
Patch foraging total patch changes 18 sec2.32.94.8-2.12.2-1.71.61.11.0-1.82.0-1.8-1.7-1.7-1.5-1.5
Patch foraging total patch changes 24 sec0.30.42.2-0.00.7-0.30.40.51.5-0.20.6-0.5-0.2-0.2-0.9-0.9
Patch foraging total patch changes 6 sec0.40.61.5-0.50.8-0.70.70.41.2-0.61.0-0.8-0.6-0.6-0.7-0.7
Patch foraging time to switch 0 sec0.40.62.2-1.50.9-0.20.31.4-1.2-0.60.2-0.3-0.3-0.40.40.4
Patch foraging water rate 0 sec0.10.20.70.8-0.4-0.30.2-0.20.90.20.20.0-0.1-0.1-0.5-0.5
Patch foraging water rate 12 sec0.50.71.3-0.50.7-1.01.11.00.4-0.80.9-0.9-1.1-1.0-0.6-0.6
Patch foraging water rate 18 sec0.60.81.3-0.20.6-1.11.20.40.9-0.81.0-1.1-1.1-1.0-0.9-0.9
Patch foraging water rate 24 sec1.82.44.1-0.91.3-1.81.91.11.0-1.61.7-1.7-2.0-2.0-1.4-1.4
Patch foraging water rate 6 sec0.30.40.90.9-0.90.6-0.6-0.5-0.10.8-0.60.60.50.60.30.3
Seeking ratio, delayed vs. immediate footshock0.10.11.0-0.4-0.00.1-0.00.1-1.0-0.0-0.10.30.10.00.30.3
Distance traveled before self-admin0.50.51.41.2-0.80.9-1.00.20.20.8-0.70.50.30.70.50.5
Distance traveled after self-admin0.10.10.70.40.20.2-0.30.00.90.1-0.1-0.2-0.1-0.00.30.3
Extensor digitorum longus weight0.20.72.61.6-0.70.6-0.61.10.60.4-0.50.80.30.3-1.2-1.2
Bone: elastic displacement3.54.05.81.8-2.42.2-2.1-1.4-1.22.4-2.42.32.42.31.11.1
Bone: elastic work1.92.53.81.4-1.91.7-1.6-1.0-1.71.7-1.71.71.41.41.51.5
Bone: endosteal estimation0.20.32.40.3-0.7-0.20.2-0.2-1.6-0.20.2-0.2-0.7-0.60.50.5
Bone: endosteal perimeter0.20.41.50.3-0.80.3-0.2-0.9-1.20.3-0.20.20.00.10.80.8
Epididymis fat weight0.20.51.50.4-1.00.7-0.5-1.1-1.20.7-0.80.60.70.50.30.3
Delta time in closed arm before/after self-admin0.30.31.90.7-0.40.4-0.4-1.40.20.2-0.30.20.30.4-0.1-0.1
Delta time in open arm before/after self-admin1.21.27.2-0.90.7-0.90.92.7-0.6-0.80.9-0.4-1.0-1.0-0.7-0.7
Diff in mean of infusions in LGA sessions0.40.42.2-0.1-0.20.5-0.5-0.4-0.50.20.10.0-0.20.31.51.5
Delay discount exponential model param1.01.02.0-1.31.3-1.21.01.40.2-1.20.8-1.2-1.0-0.9-0.2-0.2
Extinction: sum of active levers before priming0.40.43.51.00.20.1-0.1-0.11.90.10.3-0.2-0.2-0.3-0.2-0.2
Active lever presses in extinction session 60.60.62.41.6-0.40.2-0.0-1.21.60.00.5-0.1-0.40.0-0.5-0.5
Bone: final force0.40.63.60.1-0.90.5-0.5-0.2-1.90.4-0.50.60.30.30.90.9
Bone: final moment0.40.73.10.5-1.10.7-0.7-0.4-1.70.6-0.70.80.50.40.90.9
Food consumed during 24 hour testing period0.20.20.50.6-0.70.4-0.40.2-0.70.4-0.40.60.30.3-0.5-0.5
Glucose0.20.30.6-0.70.7-0.50.50.10.3-0.60.6-0.8-0.8-0.50.30.3
Heart weight3.14.47.3-2.02.1-2.52.50.90.1-2.62.5-2.6-2.7-2.6-0.9-0.9
Delay discount hyperbolic model param1.31.32.8-1.41.5-1.31.11.70.2-1.41.0-1.4-1.1-1.0-0.3-0.3
Intermittent access intake day 1-15 change1.51.53.1-0.3-1.11.4-1.5-0.2-1.71.3-1.31.51.61.80.40.4
Intermittent access intake escalation2.02.03.90.3-1.51.6-1.7-0.9-1.51.6-1.51.61.82.00.40.4
Intermittent access intake escalation 21.31.32.80.4-1.21.3-1.4-0.5-0.81.3-1.21.41.61.70.20.2
Intermitt. access day 1 inactive lever presses1.31.43.9-0.3-0.90.6-0.6-1.0-2.00.7-1.31.00.90.71.91.9
Intermitt. access day 15 inactive lever presses1.82.08.6-0.8-1.01.0-0.9-1.2-2.90.9-1.10.91.00.92.02.0
Intermitt. access escalation Index1.51.32.2-1.41.2-1.41.30.80.1-1.51.4-1.2-1.4-1.3-0.1-0.1
Intermittent access day 1 total infusions0.40.42.10.30.4-0.30.2-0.91.4-0.50.7-1.0-0.7-0.50.00.0
Intermittent access day 15 total infusions0.60.71.20.9-0.90.9-1.1-1.10.30.8-0.50.60.81.1-0.4-0.4
Intermittent access terminal intake (last 3 days)0.30.30.80.3-0.40.7-0.9-0.40.30.5-0.30.40.60.9-0.5-0.5
Intermittent access total infusions0.20.21.00.4-0.10.2-0.4-0.71.00.10.2-0.20.00.3-0.5-0.5
Intermittent access day 1 locomotion1.81.83.1-0.51.2-1.41.40.11.5-1.61.8-1.7-1.8-1.4-1.2-1.2
Intermittent access day 15 total locomotion0.50.50.9-0.50.8-0.50.60.30.8-0.70.8-0.9-0.8-0.5-0.9-0.9
Intermittent access total locomotion1.61.82.5-1.01.5-1.31.20.51.3-1.51.5-1.6-1.5-1.2-1.4-1.4
Intermittent access standard deviation0.40.51.6-0.6-0.50.6-0.7-1.2-1.30.4-0.30.40.60.90.30.3
Left kidney weight1.44.010.13.2-2.92.2-2.2-1.2-0.82.2-2.12.31.81.70.60.6
Right kidney weight1.85.010.23.1-3.22.4-2.6-2.5-1.02.5-1.92.22.02.11.11.1
Cocaine induced anxiety0.20.20.6-0.80.00.2-0.40.6-0.70.1-0.20.30.30.40.40.4
Post-drug Anxiety0.50.61.0-0.2-0.50.8-0.80.3-1.00.7-0.90.90.80.60.80.8
Baseline Anxiety0.10.10.20.5-0.40.3-0.2-0.2-0.40.4-0.40.50.40.30.40.4
Tail length1.75.28.22.2-2.92.6-2.7-1.9-1.82.6-2.42.62.32.21.61.6
Length with tail2.38.314.73.5-3.83.3-3.2-2.4-1.33.3-3.13.43.23.11.01.0
Length without tail1.22.76.82.6-2.31.7-1.5-1.90.31.6-1.61.61.71.6-0.6-0.6
Times rat made contact with spout0.60.71.40.4-0.91.1-1.1-0.1-0.91.0-1.01.21.01.00.30.3
Lifetime Intake0.40.40.90.7-0.70.8-1.0-0.90.30.7-0.40.40.60.9-0.1-0.1
Liver weight, left0.20.32.5-0.3-0.50.4-0.40.5-1.60.1-0.20.70.10.1-0.4-0.4
Liver weight, right0.71.22.51.0-1.41.2-1.3-1.6-1.01.2-1.01.31.11.00.40.4
Locomotor activity1.82.94.0-1.71.3-1.91.91.5-0.6-1.92.0-1.5-1.9-1.6-1.9-1.9
Locomotor testing distance2.33.96.0-1.21.5-2.42.50.50.5-2.22.4-2.3-2.2-2.2-2.1-2.1
Locomotor testing rearing0.40.51.6-1.10.4-0.60.61.1-1.3-0.60.7-0.5-0.7-0.6-0.5-0.5
Locomotion in novel chamber0.80.95.10.70.6-0.40.6-1.22.3-0.60.6-1.0-0.6-0.7-0.9-0.9
Locomotion in novel chamber post-restriction0.30.31.41.2-0.50.2-0.2-0.11.10.20.00.10.00.1-0.7-0.7
Fecal boli incidents, locomotor time 11.11.22.10.4-0.81.4-1.4-0.5-0.61.2-1.11.11.11.11.31.3
Change in fecal boli incidents, locomotor task0.20.20.80.9-0.4-0.40.5-0.40.3-0.20.1-0.3-0.4-0.5-0.6-0.6
Time >=10cm from walls, locomotor time 12.32.33.6-0.81.0-1.71.81.50.2-1.71.6-1.3-1.8-1.7-1.9-1.9
Bouts of movement, locomotor time 10.20.20.9-0.70.20.4-0.50.2-0.40.10.2-0.1-0.4-0.10.90.9
Total resting periods, locomotor time 10.30.30.9-0.80.40.3-0.30.6-0.5-0.00.1-0.2-0.5-0.30.90.9
Rest time, locomotor task time 10.70.82.7-1.60.6-0.40.31.1-1.6-0.70.8-0.7-0.9-0.50.60.6
Distance moved, locomotor task time 10.50.52.21.3-0.30.1-0.2-0.61.50.3-0.40.30.70.5-0.9-0.9
Vertical activity count, locomotor time 11.01.03.70.40.8-1.01.10.21.9-0.80.6-0.7-0.5-0.6-1.5-1.5
Time >=10cm from walls, locomotor time 20.50.51.5-0.20.6-0.91.00.21.2-0.50.5-0.9-0.6-0.7-0.6-0.6
Bouts of movement, locomotor time 21.11.23.0-0.11.1-1.01.10.71.7-0.90.9-1.2-1.4-1.4-0.9-0.9
Total resting periods, locomotor time 21.61.73.0-0.81.5-1.31.31.31.4-1.31.3-1.4-1.7-1.6-1.0-1.0
Rest time, locomotor task time 21.71.93.4-1.91.2-1.21.31.7-1.0-1.61.4-1.3-1.8-1.7-0.6-0.6
Distance moved, locomotor task time 20.20.20.80.7-0.30.1-0.1-0.50.90.5-0.30.30.70.3-0.2-0.2
Vertical activity count, locomotor time 21.11.22.4-0.71.1-1.51.60.61.3-1.01.1-1.3-0.8-1.0-0.9-0.9
Light reinforcement 10.81.43.30.9-1.31.2-1.2-1.8-0.51.3-1.20.91.21.11.21.2
Light reinforcement 20.40.51.00.1-0.60.7-0.6-0.3-0.70.7-1.00.91.00.90.60.6
Bone: marrow area0.20.42.60.2-0.7-0.20.3-0.2-1.6-0.30.3-0.3-0.7-0.70.40.4
Bone: maximum diameter0.50.94.20.7-1.50.5-0.5-1.6-2.00.4-0.40.50.10.20.80.8
Bone: maximum force0.20.32.1-0.2-0.40.1-0.1-0.4-1.40.00.00.1-0.1-0.20.90.9
Bone: maximum moment0.20.31.70.2-0.70.3-0.3-0.6-1.30.3-0.20.20.0-0.00.80.8
Mean time between licks in bursts0.10.10.50.2-0.30.3-0.30.5-0.30.3-0.50.70.40.3-0.1-0.1
Mean num. licks in bursts0.10.10.70.8-0.30.1-0.10.20.20.1-0.10.30.0-0.0-0.5-0.5
Cd content in liver2.42.714.1-3.81.8-1.31.31.8-2.1-1.31.3-1.0-0.9-0.80.50.5
Co content in liver0.50.62.6-1.10.3-0.20.20.5-1.6-0.40.3-0.1-0.5-0.41.11.1
Cu content in liver0.40.51.01.0-1.00.7-0.80.2-0.30.7-0.71.00.70.7-0.2-0.2
Fe content in liver0.40.51.40.30.2-0.50.60.60.6-0.70.5-0.6-0.6-0.7-1.2-1.2
K content in liver1.41.46.12.5-1.70.9-0.9-0.91.01.0-0.91.10.90.9-0.8-0.8
Mg content in liver0.70.83.61.9-0.70.0-0.0-1.31.60.2-0.10.0-0.1-0.1-0.8-0.8
Mn content in liver0.60.73.41.8-1.20.5-0.4-1.10.60.7-0.50.80.30.4-0.4-0.4
Na content in liver0.40.42.11.4-1.00.1-0.1-0.40.0-0.00.10.3-0.4-0.2-1.1-1.1
Rb content in liver0.50.60.90.5-0.40.9-0.8-0.30.00.7-0.90.90.90.90.90.9
Se content in liver0.40.42.31.5-1.10.6-0.7-0.70.10.5-0.50.40.10.10.40.4
Sr content in liver1.41.32.4-1.01.0-1.31.21.2-0.2-1.21.2-1.1-1.5-1.5-0.7-0.7
Zn content in liver0.50.52.2-0.7-0.10.3-0.40.2-1.50.2-0.30.30.10.21.31.3
Bone: minimum diameter0.71.35.6-0.3-1.00.6-0.6-1.0-2.40.6-0.50.50.30.41.91.9
Time in familiar zone, hab. session 11.01.01.7-0.50.9-1.11.1-0.20.8-1.01.3-1.3-1.2-1.2-0.8-0.8
Time in novel zone, hab. session 10.40.31.9-1.10.3-0.20.20.7-1.4-0.30.1-0.0-0.2-0.10.50.5
Total zone transitions, hab. session 10.81.13.61.9-0.6-0.50.5-1.21.8-0.10.4-0.4-0.5-0.5-1.5-1.5
Total locomotion distance, hab. session 10.50.73.01.7-0.80.1-0.0-1.31.60.5-0.20.10.20.1-0.6-0.6
Locomotion velocity, hab. session 11.11.56.32.5-1.50.8-0.7-1.61.71.2-0.90.81.00.9-0.5-0.5
Time in familiar zone, hab. session 22.02.14.9-2.21.8-1.61.51.50.3-1.51.6-1.3-1.1-1.2-1.2-1.2
Time in novel zone, hab. session 21.21.21.81.3-1.21.1-1.0-1.3-0.71.1-1.10.80.60.81.31.3
Total zone transitions, hab. session 20.81.03.61.1-0.2-0.90.90.60.9-0.60.8-0.3-1.0-0.8-1.9-1.9
Total locomotion distance, hab. session 20.10.10.40.6-0.2-0.20.30.00.50.00.10.1-0.2-0.1-0.5-0.5
Locomotion velocity, hab. session 20.20.30.90.8-0.2-0.40.5-0.01.0-0.10.3-0.1-0.4-0.3-0.8-0.8
Novel to familiar place preference ratio0.20.20.7-0.60.9-0.20.3-0.00.8-0.30.3-0.4-0.2-0.20.50.5
Novelty place preference0.30.30.9-1.00.9-0.30.3-0.10.5-0.40.4-0.5-0.2-0.20.70.7
Time in novel zone, NPP test0.30.30.8-0.80.8-0.20.2-0.20.4-0.20.2-0.3-0.1-0.10.90.9
Total zone transitions, NPP test0.71.13.01.6-1.70.9-0.9-1.0-0.71.1-1.01.20.90.90.10.1
Total locomotion distance, NPP test0.50.71.10.7-1.10.8-0.7-0.7-0.41.0-1.00.91.01.00.70.7
Locomotion velocity, NPP test0.20.30.60.6-0.80.4-0.3-0.5-0.00.7-0.60.50.60.60.30.3
Intraocular pressure0.20.31.40.30.10.5-0.5-0.11.20.6-0.40.40.70.8-0.1-0.1
Delta distance traveled before/after self-admin0.10.10.5-0.70.5-0.10.1-0.1-0.1-0.2-0.1-0.10.1-0.20.50.5
Delta ambulatory time before/after self-admin0.40.51.3-0.51.0-0.60.7-0.51.1-0.70.6-0.9-0.5-0.7-0.1-0.1
Parametrial fat weight0.20.30.6-0.50.2-0.60.60.4-0.8-0.70.6-0.5-0.7-0.8-0.6-0.6
Pavlov. Cond. lever latency2.93.67.3-2.72.4-2.12.01.00.3-2.22.1-2.4-2.1-2.1-0.6-0.6
Pavlov. Cond. magazine entry latency0.40.51.71.3-1.10.6-0.5-0.7-0.20.7-0.60.60.40.50.30.3
Pavlov. Cond. change in total contacts4.24.57.12.0-2.62.2-2.1-1.1-1.72.3-2.32.72.22.41.61.6
Pavlov. Cond. index score2.22.76.02.4-2.31.7-1.6-1.3-0.51.8-1.71.91.61.70.70.7
Pavlov. Cond. latency score2.63.37.22.7-2.51.9-1.9-1.2-0.62.0-2.02.21.81.80.80.8
Pavlov. Cond. lever contacts2.32.75.62.4-2.31.7-1.7-1.1-0.61.8-1.72.11.71.70.60.6
Pavlov. Cond. magazine entry number0.81.02.3-1.51.5-1.00.90.80.7-1.11.1-1.1-0.8-0.9-0.6-0.6
Pavlov. Cond. intertrial magazine entries0.40.41.20.3-0.50.6-0.7-1.10.60.8-0.50.51.00.80.20.2
Pavlov. Cond. lever-magazine prob. diff.2.22.85.72.4-2.31.7-1.6-1.2-0.61.8-1.72.01.71.70.60.6
Pavlov. Cond. response bias1.31.63.41.8-1.91.2-1.1-1.1-0.61.4-1.31.51.21.30.50.5
Pavlov. Cond. lever latency0.60.82.70.3-0.60.7-0.7-1.1-0.40.8-0.80.40.70.61.61.6
Pavlov. Cond. magazine entry latency2.63.08.3-2.92.1-1.81.81.7-0.4-1.81.8-1.3-1.3-1.3-1.6-1.6
Pavlov. Cond. change in total contacts0.91.23.8-0.30.8-1.00.90.30.9-1.01.2-0.8-0.8-0.8-2.0-2.0
Pavlov. Cond. index score0.81.12.5-1.31.0-0.90.91.1-0.1-1.01.0-0.6-0.6-0.6-1.6-1.6
Pavlov. Cond. latency score0.60.82.2-1.10.8-0.80.70.8-0.2-0.80.8-0.4-0.5-0.4-1.5-1.5
Pavlov. Cond. lever contacts0.91.23.3-0.50.8-1.00.91.10.5-1.11.1-0.7-1.0-0.9-1.8-1.8
Pavlov. Cond. magazine entry number0.91.03.61.9-1.31.1-1.1-0.80.41.0-1.10.70.60.60.90.9
Pavlov. Cond. intertrial magazine entries0.50.73.01.7-1.20.8-0.8-1.00.50.7-0.60.30.30.50.60.6
Pavlov. Cond. lever-magazine prob. diff.0.70.92.7-1.10.9-0.90.80.8-0.1-0.91.0-0.5-0.6-0.6-1.6-1.6
Pavlov. Cond. response bias2.02.74.3-1.61.7-1.71.71.70.4-1.81.8-1.3-1.5-1.5-2.1-2.1
Time in closed arm before self-admin0.00.10.3-0.40.2-0.10.00.5-0.0-0.1-0.0-0.1-0.1-0.1-0.3-0.3
Time in closed arm after self-admin0.60.61.50.5-0.41.0-1.0-1.00.10.8-1.20.60.90.90.60.6
Time in open arm before self-admin0.40.53.81.0-0.50.00.2-1.90.80.10.1-0.20.00.0-0.3-0.3
Time in open arm after self-admin1.31.52.2-0.60.7-1.31.41.4-0.1-1.21.5-0.9-1.3-1.4-1.5-1.5
Bone: periosteal estimation0.61.26.90.6-1.60.7-0.7-1.0-2.60.6-0.60.70.20.21.21.2
Bone: periosteal perimeter0.91.63.31.2-1.81.1-1.1-1.6-1.81.0-1.01.00.70.71.31.3
Bone: post-yield work1.21.73.4-1.41.3-1.51.5-0.70.6-1.31.6-1.8-1.5-1.40.60.6
Progressive ratio test 1 active lever presses1.11.13.20.50.4-0.80.7-1.81.6-0.81.2-1.2-1.1-0.8-0.9-0.9
Progressive ratio test 1 breakpoint1.01.12.70.40.5-0.80.7-1.61.7-0.91.2-1.2-1.1-0.8-0.8-0.8
Progressive ratio test 1 inactive lever presses0.50.51.8-1.30.4-0.50.50.3-1.2-0.40.4-0.5-0.5-0.40.90.9
Progressive ratio test 2 active lever presses1.51.65.61.9-1.11.4-1.4-2.41.21.2-1.00.71.01.2-0.2-0.2
Progressive ratio test 2 breakpoint1.51.76.12.0-1.21.4-1.3-2.51.21.2-1.00.71.01.1-0.3-0.3
Progressive ratio test 2 inactive lever presses0.60.71.40.6-0.81.0-1.1-1.2-0.20.8-0.90.70.90.90.40.4
Incentive Sensitization - Responses1.41.42.81.6-1.01.4-1.3-1.71.11.3-1.30.91.21.20.10.1
Incentive Sensitization - Breakpoint1.11.12.11.5-0.81.2-1.1-1.41.01.1-1.20.81.11.1-0.1-0.1
Sum of active levers in priming session hrs 5-60.20.21.00.60.1-0.10.2-0.71.0-0.20.4-0.4-0.5-0.30.10.1
Progressive ratio0.50.53.01.0-0.60.3-0.2-1.70.70.6-0.50.20.60.60.70.7
Food seeking constrained by brief footshock0.20.30.60.6-0.70.4-0.5-0.8-0.30.6-0.60.40.60.40.50.5
Seeking ratio, punishment vs. effort0.30.41.3-0.40.2-0.40.31.2-0.5-0.50.4-0.3-0.6-0.7-0.8-0.8
Retroperitoneal fat weight0.10.30.9-0.70.2-0.40.5-0.2-1.0-0.50.5-0.6-0.7-0.6-0.4-0.4
Reaction time number correct0.91.22.1-1.01.1-1.41.41.41.0-1.11.2-0.8-0.9-0.8-1.0-1.0
Reaction time mean minus median0.70.91.70.4-0.71.3-1.20.4-0.90.9-1.11.10.90.90.90.9
Reaction time mean minus median AUC0.60.71.30.0-0.51.1-1.10.4-0.80.7-1.01.00.90.90.90.9
Reaction time num false alarms2.02.84.90.8-1.91.8-1.8-1.3-2.21.5-1.41.81.71.81.51.5
Reaction time num false alarms AUC1.31.75.30.3-1.61.3-1.3-0.9-2.31.1-1.01.51.31.51.11.1
Reaction time trials correct on left0.91.22.1-1.01.1-1.41.41.41.0-1.11.2-0.8-0.9-0.8-1.0-1.0
Reaction time trials on left0.91.32.3-1.01.2-1.41.41.51.1-1.11.3-0.9-1.0-0.8-1.0-1.0
Reaction time mean0.10.20.70.2-0.10.7-0.7-0.1-0.10.2-0.30.10.10.10.80.8
Reaction time mean AUC0.10.10.40.10.20.3-0.4-0.10.2-0.1-0.0-0.2-0.2-0.20.60.6
Median of all reaction times0.10.20.70.00.10.4-0.4-0.40.0-0.0-0.1-0.3-0.2-0.20.80.8
Reaction time omissions0.60.81.3-1.00.9-0.80.91.10.0-1.01.0-0.8-1.0-1.1-0.6-0.6
Reaction time false alarm rate2.43.37.50.9-2.11.9-2.0-1.8-2.71.6-1.61.81.71.81.51.5
Reaction time premature initiation rate0.50.71.6-0.4-0.40.9-1.01.1-1.30.7-0.51.00.80.80.60.6
Reaction time premature initiations0.20.32.7-0.90.5-0.20.11.7-0.2-0.30.60.1-0.1-0.1-0.2-0.2
Std. dev. reaction times0.10.20.4-0.40.20.5-0.50.5-0.40.1-0.10.20.20.10.60.6
Reaction time trials completed0.91.32.3-1.01.2-1.41.41.51.1-1.11.3-0.9-1.0-0.8-1.0-1.0
Reaction time trials AUC0.50.81.5-0.70.8-1.11.11.20.9-0.81.0-0.6-0.6-0.5-0.9-0.9
Run reversals in cocaine runway, females2.42.33.8-1.61.9-1.61.61.80.5-1.71.7-1.5-1.6-1.6-1.0-1.0
Run reversals in cocaine runway, males0.70.61.10.6-1.01.0-1.0-0.5-0.50.9-0.90.90.90.90.50.5
Latency to leave start box in cocaine runway2.62.96.6-1.1-0.71.4-1.5-0.2-2.61.2-1.31.51.62.12.52.5
Latency to leave start box in cocaine runway, F2.62.84.6-0.1-1.11.8-1.90.1-2.01.6-1.71.91.92.12.02.0
Latency to leave start box in cocaine runway, M1.00.94.8-1.80.10.1-0.2-0.5-2.2-0.1-0.00.10.30.71.31.3
Std. dev. time between licks in bursts1.11.32.81.0-1.51.1-1.0-0.2-1.71.1-1.21.41.11.00.70.7
Total sessions with >9 infusions0.30.32.10.8-0.70.1-0.2-1.40.10.20.4-0.2-0.20.0-0.5-0.5
Short access day 1 total inactive lever presses0.20.20.6-0.70.3-0.40.5-0.1-0.6-0.40.4-0.5-0.5-0.5-0.1-0.1
Short access day 10 total inactive lever presses2.02.27.8-2.81.5-1.51.51.7-1.9-1.51.0-0.9-1.3-1.40.60.6
Short access day 1 total infusions0.50.52.60.2-1.00.7-0.6-0.7-1.60.6-0.40.80.40.50.20.2
Short access day 10 total infusions0.20.20.8-0.60.5-0.30.0-0.10.4-0.50.9-0.6-0.50.0-0.4-0.4
Short access total infusions0.30.30.80.2-0.70.7-0.9-0.2-0.60.6-0.30.60.50.70.10.1
Short access day 1 locomotion0.10.20.60.7-0.60.1-0.1-0.8-0.10.1-0.30.20.2-0.2-0.3-0.3
Short access day 10 total locomotion0.80.91.5-0.70.8-1.11.2-0.40.3-1.11.1-1.2-1.2-1.2-0.7-0.7
Short access total locomotion0.91.01.6-0.30.6-1.11.1-0.10.7-1.11.2-0.9-1.2-1.1-1.3-1.3
One hour access (0.3 mA shock)1.92.27.11.5-1.91.7-1.7-2.7-0.31.5-1.21.01.41.70.40.4
Compulsive drug intake0.90.93.3-1.50.9-0.81.11.8-0.9-0.70.6-0.7-0.8-0.9-0.0-0.0
One hour access (shock baseline)2.12.47.31.8-1.81.7-1.9-2.70.31.5-1.31.11.51.90.40.4
Social response proportion0.20.20.8-0.1-0.20.0-0.1-0.5-0.7-0.0-0.50.30.30.30.90.9
Social responses0.40.61.91.2-1.20.4-0.4-1.4-0.50.5-0.70.60.60.6-0.0-0.0
Social time1.72.38.7-2.81.0-0.80.82.2-3.0-0.90.6-0.4-0.8-0.61.41.4
Soleus weight0.41.22.21.5-1.40.9-0.90.1-0.10.9-0.81.31.21.2-1.3-1.3
Bone: stiffness0.10.20.4-0.50.2-0.40.40.6-0.7-0.50.4-0.2-0.6-0.60.10.1
Tibialis anterior weight0.10.21.00.3-0.00.3-0.31.00.40.2-0.10.20.30.3-0.7-0.7
Time to tail flick, vehicle, before self-admin2.22.24.0-0.0-1.01.5-1.4-0.5-1.61.7-2.01.62.01.61.71.7
Time to tail flick, vehicle, after self-admin0.70.74.0-0.4-0.70.6-0.61.2-2.00.4-0.71.00.60.50.40.4
Time to tail flick, test, before self-admin0.60.61.4-0.60.00.7-0.40.7-0.90.7-1.20.70.80.41.01.0
Time to tail flick, test, after self-admin0.40.41.7-1.30.3-0.10.21.2-1.1-0.20.00.40.20.0-0.3-0.3
Delta time to tail flick, vehicle, before/after SA1.81.83.3-0.30.7-1.21.21.80.4-1.51.5-0.9-1.7-1.4-1.8-1.8
Delta time to tail flick, test, before/after SA0.60.61.5-1.20.6-0.80.60.7-0.4-0.81.1-0.5-0.7-0.6-0.7-0.7
Tibia length7.721.631.14.3-5.65.2-5.2-4.2-2.85.2-5.04.95.25.03.53.5
Ambulatory time before self-admin0.30.31.00.6-0.30.7-0.91.00.10.5-0.40.30.00.60.20.2
Ambulatory time after self-admin0.30.42.20.20.8-0.20.20.41.5-0.30.4-0.8-0.7-0.40.10.1
Bone: tissue strength0.90.83.6-0.6-0.80.4-0.4-1.4-1.90.6-0.30.40.70.61.11.1
Total heroin consumption0.91.15.41.5-1.00.7-0.7-2.30.60.9-0.50.30.50.81.01.0
Bone: trabecular number0.50.71.2-1.01.1-1.01.10.90.1-0.90.8-1.0-1.0-1.00.10.1
Bone: trabecular spacing0.10.20.40.0-0.50.6-0.6-0.0-0.70.4-0.50.50.50.5-0.0-0.0
Bone: trabecular thickness0.60.72.70.10.8-0.80.8-0.21.7-0.80.8-0.9-0.9-1.0-0.7-0.7
Bone: trabecular tissue density0.81.11.7-0.1-0.61.2-1.2-0.3-1.11.0-1.11.11.21.11.31.3
Water consumed over 24 hours0.20.21.9-0.6-0.20.0-0.00.3-1.40.10.00.40.10.2-0.4-0.4
Number of responses in last shaping day1.01.12.20.7-1.41.2-1.1-1.5-1.30.9-0.90.90.70.70.80.8