Hub : Genes

Atxn10

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability Atxn10 0.04 0.03 6.1e-04 0.03 0.02 0.03 0.03 2.8e-04 2.2e-03 2.0e-04 8.3e-04
2 PL gene expression Atxn10 0.31 0.14 0.0e+00 0.19 0.21 0.2 0.21 7.4e-21 3.6e-23 1.2e-21 4.4e-23
3 OFC gene expression Atxn10 0.25 0.13 1.7e-04 0.11 0.1 0.09 0.08 1.2e-03 2.3e-03 4.2e-03 5.8e-03
4 Liver gene expression Atxn10 0.39 0.11 0.0e+00 0.23 0.25 0.25 0.25 1.0e-25 9.7e-28 9.2e-28 5.7e-28
5 pVTA gene expression Atxn10 0.25 0.11 7.3e-08 0.13 0.15 0.14 0.14 4.2e-06 3.3e-07 8.0e-07 1.5e-06
6 NAcc gene expression Atxn10 0.12 0.06 2.6e-14 0.1 0.13 0.13 0.13 3.0e-11 4.5e-15 4.0e-15 3.6e-15
7 Brain gene expression Atxn10 0.49 0.11 0.0e+00 0.29 0.19 0.31 0.28 5.7e-27 2.3e-17 4.6e-29 2.9e-26
8 IL gene expression Atxn10 0.27 0.12 7.6e-05 0.17 0.16 0.12 0.14 7.4e-05 1.1e-04 9.5e-04 3.9e-04
9 Adipose gene expression Atxn10 0.38 0.11 0.0e+00 0.17 0.18 0.17 0.18 3.5e-18 1.5e-19 1.0e-18 3.4e-19
10 BLA gene expression Atxn10 0.41 0.2 1.3e-09 0.06 0.11 0.18 0.14 3.0e-04 2.7e-06 1.0e-09 1.0e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.61.02.11.1-1.21.41.4-0.8-1.10.70.70.20.8
Area under the delay curve1.41.55.32.3-1.31.62.0-0.4-0.80.7-0.40.60.3
BMI with tail2.89.014.1-2.73.8-3.0-1.53.53.5-3.6-3.12.2-2.5
BMI without tail1.32.64.9-1.92.2-1.9-1.81.21.7-1.9-1.4-0.1-1.1
Body weight0.93.98.9-3.02.5-2.4-2.21.42.2-2.1-1.00.0-0.9
Weight adjusted by age1.11.22.9-1.71.5-1.2-1.20.90.9-1.2-0.50.4-1.0
Bone surface0.20.41.20.8-0.60.91.1-0.4-0.50.20.10.10.6
Bone volume0.30.50.90.9-0.80.80.9-0.7-0.70.50.5-0.10.6
Breakpoint value in progressive ratio session0.40.41.4-0.10.6-0.30.21.10.4-0.5-0.71.2-0.6
Number of licking bursts0.81.02.10.3-1.00.90.5-1.4-1.30.91.3-0.70.9
Context. condit. distance diff. score1.41.74.7-1.01.2-2.0-2.21.01.5-0.6-1.0-0.7-0.8
Locomotion velocity, session 10.50.51.6-0.90.7-0.9-0.9-0.00.6-0.2-0.4-1.30.3
Locomotion distance, session 10.50.71.90.2-0.80.1-0.2-1.3-0.71.10.0-1.41.0
Locomotion velocity, session 21.61.94.1-1.91.9-2.0-1.70.91.1-1.4-0.5-0.4-0.6
Locomotion distance, session 20.20.21.10.30.10.00.60.40.1-0.2-1.00.6-0.1
Locomotion velocity, session 31.92.27.4-1.40.9-2.0-2.7-0.60.5-0.00.8-2.5-0.3
Locomotion distance, session 30.80.92.5-0.3-0.4-0.3-0.9-1.3-0.90.91.2-1.60.8
Stereotopy head waving bouts, day 31.61.83.1-0.91.4-1.6-1.41.21.7-1.4-1.8-0.2-1.4
Stereotopy head waving duration, day 32.32.84.3-1.92.0-2.1-1.91.31.9-1.7-1.3-0.1-1.6
Locomotion velocity, session 71.31.43.9-1.61.2-1.9-2.0-0.10.7-0.80.2-0.9-1.0
Locomotion distance, session 70.10.20.5-0.4-0.1-0.4-0.7-0.5-0.00.2-0.1-0.60.3
Stereotopy head waving bouts, day 71.51.74.3-1.61.6-2.0-2.10.80.7-0.9-0.2-0.7-1.0
Stereotopy head waving duration, day 70.60.72.0-1.11.0-1.2-1.40.40.3-0.50.0-0.5-0.7
Locomotion velocity, session 84.55.410.0-2.23.1-3.2-2.42.52.4-2.4-1.30.3-2.1
Locomotion distance, session 80.71.13.0-0.60.9-1.7-1.60.80.9-0.2-1.2-0.8-0.4
Degree of sensitization distance1.51.54.3-0.41.0-0.8-0.31.51.7-1.2-2.11.0-0.9
Degree of sensitization stereotypy0.60.71.8-1.11.0-1.3-1.30.40.2-0.50.0-0.4-0.5
Conditioned locomotion0.10.10.3-0.5-0.1-0.2-0.3-0.4-0.20.20.2-0.00.1
Cocaine response after cond. corrected0.50.51.2-0.3-0.50.80.7-0.9-1.00.40.8-0.11.1
Cocaine response after cond. not corrected1.11.23.0-0.4-0.70.80.5-1.4-1.50.81.7-0.61.4
Cocaine response before conditioning0.40.51.70.3-0.50.2-0.2-0.9-0.70.81.3-0.80.4
Saline control response0.70.92.1-0.2-0.80.60.0-1.1-1.21.31.4-0.61.3
Bone: connectivity density0.40.61.10.9-0.91.10.9-0.7-0.70.50.4-0.20.7
Bone: cortical apparent density0.40.51.61.2-1.11.11.0-0.2-0.10.70.00.10.2
Bone: cortical area0.50.81.8-1.31.0-0.9-0.60.70.7-1.10.10.9-0.9
Bone: cortical porosity0.40.40.8-0.50.8-0.6-0.20.50.5-0.8-0.40.9-0.8
Bone: cortical porosity0.50.50.9-0.60.9-0.7-0.20.70.5-0.9-0.50.9-0.9
Bone: cortical thickness0.10.20.90.2-0.30.40.70.20.2-0.20.00.9-0.4
Bone: cortical thickness0.91.11.8-1.10.8-0.8-0.40.91.3-1.3-0.81.3-1.3
Bone: cortical tissue density0.30.41.21.1-1.00.90.8-0.10.00.6-0.10.10.1
Condit. Reinf. active minus inactive responses0.50.51.21.0-0.90.91.1-0.6-0.60.50.10.10.4
Condit. Reinf. active-inactive response ratio0.80.81.81.4-1.31.21.1-0.7-0.70.90.0-0.10.6
Condit. Reinf. active responses1.01.32.01.4-1.41.41.2-1.2-1.01.10.4-0.61.1
Condit. Reinf. inactive responses0.50.61.20.6-0.70.80.3-0.9-0.60.90.5-1.11.1
Incentive salience index mean0.50.61.50.4-0.90.70.5-1.2-0.70.70.8-0.60.8
Condit. Reinf. lever presses0.60.82.2-0.6-0.30.1-0.4-1.4-0.60.61.5-1.31.0
Condit. Reinf. active minus inactive responses0.40.50.9-0.30.9-0.7-0.20.80.6-1.0-0.90.8-0.5
Condit. Reinf. active-inactive response ratio0.10.10.4-0.30.2-0.10.30.2-0.2-0.5-0.10.60.2
Condit. Reinf. active responses1.52.13.7-0.91.9-1.7-1.01.61.6-1.7-1.60.9-1.2
Condit. Reinf. inactive responses2.53.15.3-1.42.3-2.1-1.61.72.2-1.8-1.80.6-1.6
Condit. Reinf. lever presses0.81.12.2-0.91.5-1.3-1.01.21.1-1.2-1.00.5-0.5
Condit. Reinf. lever reinforcers received1.11.52.8-0.71.7-1.4-0.71.51.3-1.4-1.40.9-1.0
Conditioned reinforcement - actives1.21.22.50.3-1.41.20.2-1.3-0.71.30.4-1.51.6
Conditioned reinforcement - inactives0.20.20.7-0.0-0.1-0.3-0.7-0.3-0.10.4-0.0-0.80.7
Conditioned locomotion0.40.42.1-1.40.8-0.4-0.80.10.1-0.40.7-0.30.2
Patch foraging indifference point 0 sec0.30.51.3-0.0-0.41.01.1-0.2-0.70.11.00.60.4
Patch foraging indifference point AUC0.10.10.50.70.10.00.20.10.10.4-0.7-0.20.1
Delay disc. indifference point, 0s delay0.10.10.20.20.20.10.30.40.5-0.5-0.40.3-0.4
Delay disc. indifference point, 16s delay2.02.14.62.1-1.62.02.2-0.8-1.41.10.40.41.0
Delay disc. indifference point, 2s delay0.40.41.31.1-0.50.71.1-0.0-0.0-0.0-0.50.6-0.3
Delay disc. indifference point, 24s delay0.50.51.70.30.4-0.00.90.80.1-0.6-0.81.3-0.6
Delay disc. indifference point, 4s delay1.11.24.42.1-0.81.31.90.2-0.10.3-0.70.8-0.1
Delay disc. indifference point, 8s delay1.11.14.72.2-1.01.21.6-0.2-0.70.6-0.60.60.2
Indifference point function ln k0.70.94.3-2.10.7-1.0-1.40.10.5-0.60.9-0.70.0
Indifference point function log k0.70.94.3-2.10.7-1.0-1.40.10.5-0.60.9-0.70.0
Patch foraging total patch changes 0 sec0.40.71.60.1-0.61.21.3-0.5-1.00.31.30.50.5
Patch foraging total patch changes 12 sec0.20.30.50.20.6-0.4-0.00.50.5-0.6-0.70.5-0.6
Patch foraging total patch changes 18 sec0.60.81.40.7-1.01.11.1-1.1-1.20.80.7-0.10.6
Patch foraging total patch changes 24 sec0.10.10.8-0.3-0.00.30.1-0.3-0.50.30.9-0.00.3
Patch foraging total patch changes 6 sec0.40.62.40.6-0.31.11.60.1-0.60.10.21.00.2
Patch foraging time to switch 0 sec0.30.51.40.40.6-0.9-0.50.40.3-0.7-0.50.7-1.2
Patch foraging water rate 0 sec0.20.31.1-1.00.60.10.10.70.2-0.50.30.5-0.1
Patch foraging water rate 12 sec0.60.92.5-1.0-0.41.00.3-0.7-1.10.81.6-0.71.2
Patch foraging water rate 18 sec0.20.20.6-0.3-0.30.70.6-0.2-0.50.30.3-0.10.8
Patch foraging water rate 24 sec0.10.20.8-0.50.4-0.10.10.90.3-0.4-0.60.2-0.1
Patch foraging water rate 6 sec0.71.02.10.2-1.00.90.2-1.1-1.01.31.4-1.31.1
Seeking ratio, delayed vs. immediate footshock0.70.81.40.8-0.81.21.2-0.4-1.00.51.10.70.6
Distance traveled before self-admin0.20.20.9-0.10.1-0.4-0.9-0.50.3-0.0-0.1-0.8-0.1
Distance traveled after self-admin0.50.51.4-1.01.2-0.7-0.80.50.3-0.80.40.5-0.7
Extensor digitorum longus weight0.20.82.4-1.51.2-1.1-0.90.70.7-0.9-0.70.0-0.2
Bone: elastic displacement0.20.20.8-0.40.2-0.1-0.4-0.1-0.40.30.9-0.70.7
Bone: elastic work1.92.55.2-1.92.3-1.9-1.41.61.3-1.8-0.40.7-1.5
Bone: endosteal estimation1.43.16.2-2.32.4-2.5-2.21.51.4-1.8-0.60.1-1.1
Bone: endosteal perimeter1.42.98.3-2.92.2-2.3-2.30.80.8-1.50.60.1-1.0
Epididymis fat weight0.10.10.4-0.30.0-0.3-0.30.20.50.0-0.2-0.50.6
Delta time in closed arm before/after self-admin0.20.20.60.10.2-0.00.20.30.4-0.5-0.60.8-0.6
Delta time in open arm before/after self-admin1.11.04.0-0.3-0.3-0.4-1.3-0.9-0.71.01.0-2.01.0
Diff in mean of infusions in LGA sessions0.70.82.70.10.00.11.00.90.9-0.7-1.31.6-0.5
Delay discount exponential model param1.51.55.7-2.41.3-1.6-2.00.40.8-0.70.5-0.6-0.3
Extinction: sum of active levers before priming0.50.51.20.90.10.51.11.00.4-0.3-1.00.9-0.1
Active lever presses in extinction session 62.32.33.9-1.01.4-0.80.12.01.7-1.8-1.81.9-1.4
Bone: final force1.32.13.7-0.61.4-0.70.01.91.8-1.8-1.61.7-1.5
Bone: final moment1.72.85.2-0.71.7-0.90.02.32.1-2.1-1.92.0-1.7
Food consumed during 24 hour testing period2.32.85.0-2.02.0-2.2-1.81.21.8-1.7-1.60.3-1.3
Glucose0.30.51.00.5-1.01.01.0-0.8-0.60.40.20.6-0.1
Heart weight0.10.10.5-0.1-0.10.20.40.30.3-0.5-0.40.7-0.3
Delay discount hyperbolic model param1.21.35.1-2.31.1-1.4-1.80.30.6-0.60.5-0.6-0.2
Intermittent access intake day 1-15 change0.50.50.80.6-0.70.50.1-0.9-0.80.80.6-0.70.8
Intermittent access intake escalation0.40.40.80.2-0.60.5-0.1-0.9-0.70.70.7-0.70.8
Intermittent access intake escalation 20.40.30.70.8-0.50.80.8-0.5-0.70.60.40.10.4
Intermitt. access day 1 inactive lever presses1.51.62.9-0.41.6-1.2-0.71.71.2-1.2-1.11.3-1.5
Intermitt. access day 15 inactive lever presses1.61.83.1-0.81.5-1.1-0.51.81.6-1.5-1.61.3-0.9
Intermitt. access escalation Index0.10.10.3-0.5-0.30.40.20.00.1-0.20.00.20.5
Intermittent access day 1 total infusions0.60.72.0-1.30.2-0.5-1.4-0.00.6-0.1-0.3-1.30.6
Intermittent access day 15 total infusions0.50.51.9-0.8-0.3-0.0-1.1-0.5-0.00.30.3-1.40.9
Intermittent access terminal intake (last 3 days)0.40.51.6-1.20.3-0.6-1.3-0.10.5-0.2-0.1-0.90.4
Intermittent access total infusions0.50.62.0-1.30.4-0.7-1.4-0.10.5-0.2-0.1-1.00.4
Intermittent access day 1 locomotion0.50.61.6-1.1-0.5-0.0-1.0-0.8-0.20.40.4-1.20.8
Intermittent access day 15 total locomotion0.91.02.8-1.5-0.0-0.6-1.7-0.6-0.10.40.7-1.60.8
Intermittent access total locomotion0.60.72.6-1.20.6-1.0-1.60.20.5-0.2-0.1-1.00.0
Intermittent access standard deviation0.40.40.80.10.7-0.9-0.50.80.7-0.4-0.80.2-0.7
Left kidney weight9.125.643.3-5.86.2-6.6-5.64.75.8-5.0-3.80.5-3.6
Right kidney weight9.426.442.2-5.46.3-6.5-5.25.16.0-5.3-4.11.1-4.1
Cocaine induced anxiety4.65.39.8-1.32.6-2.0-0.83.12.6-2.5-2.72.0-2.4
Post-drug Anxiety4.85.39.8-0.92.4-1.50.33.12.2-2.6-2.53.1-2.6
Baseline Anxiety2.12.33.90.9-2.01.91.6-1.8-1.81.31.5-0.21.2
Tail length0.72.17.20.4-1.30.7-0.7-2.0-1.11.41.3-2.71.6
Length with tail0.31.13.7-0.6-0.4-0.3-1.3-1.2-0.40.71.1-1.91.1
Length without tail0.10.20.6-0.40.4-0.6-0.40.70.8-0.2-0.30.20.1
Times rat made contact with spout0.50.61.4-0.50.5-0.8-0.90.11.1-0.5-1.2-0.90.0
Lifetime Intake0.70.83.2-1.40.6-0.9-1.8-0.10.6-0.3-0.1-1.20.3
Liver weight, left0.61.03.7-0.20.8-0.7-0.41.01.5-1.0-1.90.3-0.6
Liver weight, right0.61.04.3-0.6-0.1-0.9-1.6-0.90.40.70.5-2.10.8
Locomotor activity1.01.65.6-2.41.2-1.5-1.60.31.0-1.40.2-0.4-0.8
Locomotor testing distance0.20.31.6-1.3-0.0-0.0-0.3-0.50.0-0.30.8-0.30.0
Locomotor testing rearing0.40.72.4-1.60.5-0.6-1.2-0.70.2-0.31.0-0.9-0.1
Locomotion in novel chamber2.32.85.2-0.2-1.41.1-0.4-2.3-1.71.72.0-2.22.1
Locomotion in novel chamber post-restriction0.10.10.6-0.70.4-0.3-0.10.2-0.1-0.3-0.20.7-0.1
Fecal boli incidents, locomotor time 10.30.40.7-0.60.9-0.6-0.50.80.7-0.6-0.40.2-0.6
Change in fecal boli incidents, locomotor task0.60.61.10.3-0.60.70.1-0.7-1.01.00.9-0.81.1
Time >=10cm from walls, locomotor time 11.11.21.9-0.81.4-1.3-0.61.11.2-1.3-0.50.9-1.3
Bouts of movement, locomotor time 10.60.61.70.00.6-0.60.10.71.0-1.0-1.30.7-0.9
Total resting periods, locomotor time 10.90.92.20.10.6-0.30.60.91.1-1.1-1.51.4-1.0
Rest time, locomotor task time 10.91.01.8-0.71.3-1.0-0.41.01.2-1.3-1.00.6-1.1
Distance moved, locomotor task time 10.10.10.2-0.40.2-0.5-0.4-0.00.2-0.20.40.2-0.3
Vertical activity count, locomotor time 10.10.10.6-0.3-0.00.20.4-0.0-0.1-0.10.60.8-0.2
Time >=10cm from walls, locomotor time 20.50.51.8-1.00.70.10.60.6-0.0-0.60.71.4-0.3
Bouts of movement, locomotor time 21.11.23.11.80.0-0.00.81.01.0-0.6-1.71.2-1.1
Total resting periods, locomotor time 21.31.34.02.00.00.10.91.01.1-0.6-1.91.2-1.0
Rest time, locomotor task time 21.21.43.21.8-1.31.31.0-1.1-0.81.2-0.1-1.51.3
Distance moved, locomotor task time 21.61.84.8-2.21.6-1.8-1.70.80.8-1.10.60.5-1.1
Vertical activity count, locomotor time 21.92.16.6-2.61.8-1.6-1.41.11.0-1.30.70.9-1.3
Light reinforcement 10.50.93.3-1.80.8-0.7-1.4-0.3-0.30.11.3-0.80.6
Light reinforcement 21.11.55.1-2.31.6-1.4-1.60.70.7-1.10.30.1-0.5
Bone: marrow area1.43.16.2-2.22.4-2.5-2.11.61.5-1.8-0.60.2-1.1
Bone: maximum diameter2.95.310.0-3.23.0-2.9-2.42.02.1-2.6-0.70.9-1.8
Bone: maximum force2.03.45.9-1.02.0-1.3-0.32.42.1-2.2-1.72.1-2.1
Bone: maximum moment2.54.37.6-1.12.3-1.4-0.32.82.4-2.5-2.02.3-2.3
Mean time between licks in bursts1.52.14.00.4-1.61.51.0-2.0-1.81.31.9-0.61.3
Mean num. licks in bursts1.72.04.8-0.61.4-1.4-1.21.72.2-1.1-2.20.1-0.9
Cd content in liver0.30.31.00.6-0.61.00.90.0-0.30.4-0.10.40.5
Co content in liver0.20.31.1-1.00.4-0.5-0.8-0.20.1-0.20.5-0.40.1
Cu content in liver3.54.27.52.1-2.22.72.7-1.5-2.71.81.70.71.5
Fe content in liver0.10.10.4-0.10.20.20.20.0-0.2-0.20.60.5-0.3
K content in liver0.30.31.30.60.4-0.10.31.10.4-0.1-0.60.9-0.2
Mg content in liver0.50.51.90.60.20.31.01.00.1-0.4-0.51.4-0.3
Mn content in liver0.50.62.3-0.90.4-1.0-1.5-0.20.50.1-0.1-1.20.3
Na content in liver1.11.22.61.6-1.31.21.6-0.5-1.31.00.10.70.5
Rb content in liver0.50.62.10.6-0.51.11.50.3-0.3-0.20.31.3-0.0
Se content in liver0.60.81.70.3-0.80.70.1-0.8-0.81.11.3-0.91.2
Sr content in liver0.90.82.50.6-1.00.4-0.3-1.3-0.71.10.2-1.60.9
Zn content in liver1.11.22.00.7-1.11.00.5-1.3-1.31.31.4-0.71.2
Bone: minimum diameter0.71.23.6-1.91.1-1.4-1.6-0.2-0.0-0.61.5-0.4-0.3
Time in familiar zone, hab. session 10.70.72.2-1.51.2-1.0-0.80.50.5-0.9-0.20.3-0.4
Time in novel zone, hab. session 10.20.20.50.5-0.70.60.4-0.5-0.40.30.10.00.2
Total zone transitions, hab. session 11.01.42.71.5-1.71.21.0-1.1-1.21.5-0.3-0.41.2
Total locomotion distance, hab. session 10.30.41.5-0.1-0.5-0.1-0.7-0.5-0.41.0-0.3-1.20.7
Locomotion velocity, hab. session 10.30.41.6-0.1-0.3-0.3-0.8-0.4-0.30.9-0.4-1.30.5
Time in familiar zone, hab. session 20.70.71.5-0.2-0.70.7-0.0-1.0-0.70.91.1-1.11.2
Time in novel zone, hab. session 20.20.20.80.7-0.20.10.50.30.00.0-0.90.5-0.3
Total zone transitions, hab. session 20.40.61.7-0.50.7-0.7-0.11.00.6-0.6-1.30.8-0.4
Total locomotion distance, hab. session 20.10.10.3-0.50.5-0.5-0.30.50.1-0.1-0.60.1-0.1
Locomotion velocity, hab. session 20.10.10.5-0.40.4-0.5-0.30.50.2-0.1-0.70.1-0.1
Novel to familiar place preference ratio0.10.10.70.2-0.10.2-0.1-0.10.00.4-0.1-0.80.3
Novelty place preference0.20.21.3-0.1-0.0-0.1-0.5-0.20.00.40.2-1.10.3
Time in novel zone, NPP test0.20.21.5-0.1-0.1-0.1-0.5-0.3-0.00.50.1-1.20.3
Total zone transitions, NPP test0.40.61.21.0-0.80.80.8-0.1-0.61.1-0.3-0.31.0
Total locomotion distance, NPP test0.10.10.40.1-0.00.0-0.20.2-0.50.6-0.0-0.30.4
Locomotion velocity, NPP test0.10.10.50.2-0.10.1-0.1-0.0-0.60.70.5-0.40.5
Intraocular pressure0.30.41.5-0.5-0.0-0.4-1.0-0.8-0.00.40.1-1.20.7
Delta distance traveled before/after self-admin0.40.41.5-1.20.9-0.5-0.60.50.0-0.40.70.0-0.3
Delta ambulatory time before/after self-admin0.20.31.3-1.10.7-0.1-0.00.5-0.1-0.40.70.4-0.0
Parametrial fat weight0.20.41.10.8-0.50.50.1-0.9-0.30.6-0.4-1.10.8
Pavlov. Cond. lever latency0.81.03.20.40.6-0.40.11.61.0-0.8-1.80.8-1.2
Pavlov. Cond. magazine entry latency0.81.01.70.7-1.01.21.3-1.1-1.10.61.20.50.8
Pavlov. Cond. change in total contacts0.60.61.80.1-0.61.01.3-0.7-0.8-0.10.61.10.4
Pavlov. Cond. index score0.50.61.40.2-0.60.70.6-1.1-0.90.51.20.20.8
Pavlov. Cond. latency score0.40.51.8-0.1-0.50.50.3-1.1-0.90.41.30.00.8
Pavlov. Cond. lever contacts1.01.23.5-0.5-0.60.4-0.2-1.8-1.10.81.9-0.91.3
Pavlov. Cond. magazine entry number0.60.81.4-0.61.0-1.2-1.21.00.9-0.6-0.8-0.4-0.9
Pavlov. Cond. intertrial magazine entries1.01.23.31.4-1.31.81.6-0.3-0.91.00.3-0.10.9
Pavlov. Cond. lever-magazine prob. diff.0.70.92.00.3-0.90.90.7-1.4-1.10.71.40.01.0
Pavlov. Cond. response bias0.91.12.80.1-1.01.10.9-1.7-1.20.71.4-0.11.3
Pavlov. Cond. lever latency0.30.40.90.4-0.90.70.4-0.8-0.50.70.3-0.40.5
Pavlov. Cond. magazine entry latency1.01.24.01.10.00.91.71.1-0.1-0.5-0.92.0-0.6
Pavlov. Cond. change in total contacts1.31.94.3-0.11.4-0.90.31.80.9-1.7-1.22.1-1.6
Pavlov. Cond. index score0.50.62.00.30.7-0.10.61.10.3-0.8-0.71.4-0.7
Pavlov. Cond. latency score0.70.82.90.10.8-0.20.61.30.5-1.1-0.81.7-0.9
Pavlov. Cond. lever contacts0.60.91.7-0.51.2-0.9-0.31.30.9-1.1-0.71.1-0.8
Pavlov. Cond. magazine entry number0.50.71.9-0.4-0.50.1-0.6-1.1-0.30.71.0-1.41.0
Pavlov. Cond. intertrial magazine entries0.91.22.7-0.21.1-0.9-0.51.41.5-1.1-1.60.9-0.9
Pavlov. Cond. lever-magazine prob. diff.0.40.51.60.20.6-0.10.51.00.3-0.7-0.51.3-0.6
Pavlov. Cond. response bias0.60.81.80.00.9-0.40.31.30.6-1.1-0.91.3-0.9
Time in closed arm before self-admin0.91.03.11.2-1.01.41.8-0.4-1.00.70.90.60.5
Time in closed arm after self-admin0.20.20.70.2-0.60.60.3-0.8-0.60.30.80.20.1
Time in open arm before self-admin0.20.20.8-0.30.2-0.6-0.9-0.30.1-0.0-0.0-0.6-0.1
Time in open arm after self-admin0.40.51.3-0.40.9-1.1-1.10.70.5-0.1-0.4-0.5-0.3
Bone: periosteal estimation1.42.85.4-2.32.2-2.2-1.81.51.4-1.9-0.40.6-1.3
Bone: periosteal perimeter1.42.48.1-2.81.9-2.1-2.00.50.7-1.50.70.1-0.8
Bone: post-yield work0.60.81.90.70.20.31.21.01.0-0.8-1.21.4-0.6
Progressive ratio test 1 active lever presses0.50.62.1-0.9-0.50.2-0.6-0.70.20.3-0.1-1.51.2
Progressive ratio test 1 breakpoint0.50.51.9-0.8-0.50.3-0.6-0.80.20.3-0.0-1.41.2
Progressive ratio test 1 inactive lever presses0.30.31.2-0.90.0-0.4-1.1-0.20.5-0.1-0.5-0.70.1
Progressive ratio test 2 active lever presses0.40.52.10.20.2-0.3-0.41.01.0-0.2-1.4-0.2-0.1
Progressive ratio test 2 breakpoint0.50.52.30.20.3-0.3-0.41.21.1-0.3-1.5-0.1-0.2
Progressive ratio test 2 inactive lever presses0.50.61.7-0.50.5-0.7-1.00.91.1-0.4-1.3-0.2-0.1
Incentive Sensitization - Responses1.31.44.00.40.9-0.7-0.42.01.5-0.8-2.00.6-0.9
Incentive Sensitization - Breakpoint1.61.64.40.31.0-0.8-0.52.11.6-0.9-2.10.6-1.1
Sum of active levers in priming session hrs 5-60.80.81.9-0.11.0-0.7-0.11.40.8-0.8-0.81.2-1.0
Progressive ratio0.10.10.40.6-0.50.30.4-0.4-0.00.3-0.4-0.30.1
Food seeking constrained by brief footshock0.50.72.2-1.50.9-0.8-0.50.60.6-0.8-0.30.8-0.8
Seeking ratio, punishment vs. effort0.81.02.3-1.31.2-0.8-0.21.20.6-1.1-0.21.5-0.9
Retroperitoneal fat weight1.03.46.5-2.42.0-2.5-2.51.12.1-1.7-1.4-0.6-0.9
Reaction time number correct0.30.40.90.3-0.50.70.5-0.6-0.80.71.0-0.40.3
Reaction time mean minus median0.20.21.21.1-0.30.40.3-0.1-0.30.40.3-0.50.2
Reaction time mean minus median AUC0.20.20.40.50.5-0.5-0.60.50.4-0.1-0.5-0.6-0.3
Reaction time num false alarms0.91.23.3-0.1-1.00.4-0.3-1.8-1.11.21.2-1.61.0
Reaction time num false alarms AUC1.21.64.10.0-1.20.3-0.6-2.0-1.21.51.0-2.01.2
Reaction time trials correct on left0.30.40.90.3-0.50.70.5-0.6-0.80.71.0-0.40.3
Reaction time trials on left0.30.40.90.3-0.60.70.5-0.6-0.90.71.0-0.40.3
Reaction time mean0.60.93.71.9-0.70.91.30.4-0.40.5-0.60.9-0.0
Reaction time mean AUC0.60.84.02.0-0.70.91.20.3-0.40.6-0.50.70.1
Median of all reaction times0.91.24.22.1-0.91.11.70.4-0.50.5-0.81.3-0.0
Reaction time omissions0.70.92.51.3-1.01.51.6-0.2-0.70.7-0.20.60.6
Reaction time false alarm rate0.50.72.1-0.2-0.8-0.1-0.8-1.4-0.50.80.4-1.50.7
Reaction time premature initiation rate2.43.26.30.11.7-1.30.12.51.9-2.0-2.32.0-2.2
Reaction time premature initiations1.31.83.80.31.2-0.80.42.01.2-1.4-1.51.5-1.9
Std. dev. reaction times0.30.42.51.6-0.60.60.60.1-0.30.7-0.2-0.20.3
Reaction time trials completed0.30.40.90.3-0.60.70.5-0.6-0.90.71.0-0.40.3
Reaction time trials AUC0.10.20.60.1-0.20.50.4-0.3-0.60.40.7-0.30.1
Run reversals in cocaine runway, females2.52.44.90.4-1.91.70.7-2.2-1.71.41.7-1.21.7
Run reversals in cocaine runway, males0.70.62.7-0.7-0.1-0.6-1.2-0.7-0.20.40.1-1.60.8
Latency to leave start box in cocaine runway0.80.82.2-1.51.1-1.1-1.30.50.9-0.8-0.4-0.0-0.6
Latency to leave start box in cocaine runway, F0.30.31.5-1.20.3-0.4-0.70.00.6-0.5-0.2-0.2-0.3
Latency to leave start box in cocaine runway, M1.01.01.9-0.91.3-1.4-1.30.91.1-0.8-0.70.1-0.7
Std. dev. time between licks in bursts0.30.41.80.20.30.40.90.7-0.0-0.5-0.51.4-0.3
Total sessions with >9 infusions1.11.23.6-1.50.3-0.8-1.9-1.0-0.10.11.0-1.70.7
Short access day 1 total inactive lever presses1.11.22.6-1.61.4-1.3-1.60.81.0-1.1-0.4-0.0-0.1
Short access day 10 total inactive lever presses1.21.32.9-0.11.7-1.4-0.71.50.9-1.1-0.71.1-1.3
Short access day 1 total infusions0.91.04.1-1.40.4-1.0-2.0-0.60.5-0.20.2-1.50.3
Short access day 10 total infusions0.50.62.6-1.60.3-0.5-1.2-0.50.4-0.30.2-0.80.6
Short access total infusions1.31.54.6-2.11.2-1.5-2.10.21.0-0.9-0.2-0.8-0.2
Short access day 1 locomotion0.10.10.4-0.4-0.1-0.0-0.5-0.5-0.10.20.6-0.30.1
Short access day 10 total locomotion1.01.12.9-0.8-0.80.1-0.9-1.7-0.60.81.0-1.61.1
Short access total locomotion0.50.52.1-1.50.4-0.6-1.1-0.50.1-0.30.6-0.40.1
One hour access (0.3 mA shock)0.40.41.8-0.50.0-0.4-1.3-0.20.10.40.5-1.20.4
Compulsive drug intake0.30.30.70.80.2-0.00.50.80.1-0.2-0.30.8-0.8
One hour access (shock baseline)0.70.92.2-1.1-0.3-0.1-1.3-1.0-0.20.60.9-1.51.1
Social response proportion0.40.41.5-1.20.8-0.7-0.80.20.5-0.60.0-0.0-0.4
Social responses0.60.82.8-1.70.8-0.8-1.4-0.30.3-0.20.6-0.90.2
Social time1.31.84.00.8-1.81.51.0-2.0-0.91.30.6-1.21.5
Soleus weight0.31.02.4-0.10.9-0.60.21.41.4-1.2-1.61.0-0.6
Bone: stiffness1.62.59.00.11.0-0.11.11.81.0-1.7-1.43.0-2.1
Tibialis anterior weight0.00.20.50.20.10.10.50.40.1-0.4-0.70.60.0
Time to tail flick, vehicle, before self-admin0.20.20.80.2-0.50.50.10.10.30.3-0.3-0.70.9
Time to tail flick, vehicle, after self-admin0.10.10.5-0.0-0.40.4-0.0-0.3-0.10.30.2-0.70.5
Time to tail flick, test, before self-admin0.60.61.9-0.80.0-0.7-1.4-0.90.10.10.4-1.30.5
Time to tail flick, test, after self-admin1.11.13.00.8-1.11.71.7-0.5-1.00.40.81.00.8
Delta time to tail flick, vehicle, before/after SA0.90.81.9-0.30.9-0.8-0.11.00.9-1.1-1.11.0-1.4
Delta time to tail flick, test, before/after SA2.01.86.51.5-1.11.92.60.2-1.20.60.51.50.4
Tibia length0.00.10.30.10.5-0.2-0.00.50.2-0.2-0.20.20.1
Ambulatory time before self-admin0.30.31.1-0.10.0-0.5-1.1-0.40.20.2-0.2-1.00.1
Ambulatory time after self-admin0.10.10.4-0.50.30.20.10.1-0.4-0.10.60.30.1
Bone: tissue strength1.11.13.10.60.50.71.31.40.3-0.8-1.11.7-0.9
Total heroin consumption1.82.14.8-0.91.7-1.1-0.12.21.4-1.3-1.51.8-1.3
Bone: trabecular number1.11.83.01.0-1.51.41.0-1.7-1.61.41.4-0.81.3
Bone: trabecular spacing3.64.78.0-2.32.8-2.8-1.92.12.1-2.5-1.41.1-1.9
Bone: trabecular thickness0.40.50.90.7-0.90.60.2-0.8-0.60.90.7-0.70.4
Bone: trabecular tissue density0.30.52.11.4-0.20.30.80.60.1-0.1-0.60.9-0.6
Water consumed over 24 hours1.31.52.6-1.51.5-1.6-1.41.11.4-1.2-0.9-0.1-1.0
Number of responses in last shaping day0.10.10.7-0.1-0.60.40.3-0.9-0.2-0.00.3-0.10.2