Hub : Genes

Atraid

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL mRNA stability Atraid 0.23 0.19 5.8e-04 0.16 0.1 0.14 0.13 1.5e-04 2.0e-03 2.9e-04 5.9e-04
2 BLA mRNA stability Atraid 0.25 0.28 9.8e-04 0.05 0.05 0.03 0.04 1.8e-03 1.9e-03 6.2e-03 3.3e-03
3 Brain mRNA stability Atraid 0.07 0.05 3.8e-08 0.06 0.08 0.06 0.07 3.1e-06 1.1e-07 4.4e-06 7.6e-07
4 LHb gene expression Atraid 0.48 0.38 2.8e-05 0.22 0.15 0.17 0.19 7.1e-06 1.8e-04 8.3e-05 2.4e-05
5 pVTA intron excision ratio chr6_31037182_31038877 0.13 0.09 2.2e-05 0.05 0.06 0.06 0.06 6.9e-05 6.8e-06 2.2e-05 1.2e-05
6 Liver gene expression Atraid 0.33 0.19 0.0e+00 0.26 0.26 0.26 0.26 3.2e-28 3.9e-28 3.0e-28 3.1e-28
7 Adipose gene expression Atraid 0.22 0.16 0.0e+00 0.16 0.16 0.16 0.16 5.4e-17 6.1e-18 8.2e-18 7.1e-18
8 Adipose mRNA stability Atraid 0.04 0.04 9.4e-04 0.02 0.02 0.02 0.02 4.4e-03 3.6e-03 3.7e-03 4.1e-03
9 PL gene expression Atraid 0.45 0.08 5.6e-17 0.17 0.15 0.16 0.16 7.0e-18 3.6e-16 1.3e-16 3.6e-17
10 NAcc mRNA stability Atraid 0.04 0.03 2.3e-07 0.04 0.04 0.04 0.04 1.9e-06 3.6e-07 1.1e-06 7.1e-07
11 PL mRNA stability Atraid 0.05 0.05 1.2e-05 0.04 0.05 0.04 0.04 3.0e-05 8.3e-06 1.3e-05 1.3e-05
12 OFC mRNA stability Atraid 0.42 0.38 1.4e-04 0.17 0.14 0.14 0.15 8.6e-05 3.7e-04 3.8e-04 2.1e-04
13 RMTg gene expression Atraid 0.21 0.12 2.2e-06 0.19 0.2 0.17 0.2 7.3e-06 5.0e-06 2.5e-05 5.7e-06
14 pVTA gene expression Atraid 0.17 0.1 4.1e-13 0.17 0.17 0.15 0.17 1.2e-13 5.7e-14 3.7e-12 7.2e-14
15 Brain gene expression Atraid 0.52 0.21 0.0e+00 0.22 0.2 0.22 0.21 2.9e-20 4.9e-18 4.1e-20 1.0e-19
16 PL intron excision ratio chr6_31037182_31038552 0.03 0.03 1.8e-03 0.03 0.03 0.03 0.03 1.7e-04 8.7e-04 2.8e-04 2.7e-04
17 IC gene expression Atraid 0.28 0.23 4.6e-03 0.03 0.04 0.02 0.02 2.2e-02 1.4e-02 3.8e-02 6.0e-02
18 NAcc gene expression Atraid 0.21 0.37 5.6e-14 0.1 0.09 0.1 0.1 3.9e-15 3.1e-13 1.2e-14 6.2e-15
19 BLA gene expression Atraid 0.16 0.16 5.5e-06 0.12 0.09 0.11 0.11 1.0e-06 1.2e-05 1.4e-06 2.8e-06
20 PL intron excision ratio chr6_31037182_31038877 0.03 0.03 8.0e-04 0.03 0.03 0.03 0.03 1.9e-04 3.6e-04 1.6e-04 2.0e-04
21 pVTA mRNA stability Atraid 0.17 0.11 1.1e-09 0.12 0.12 0.11 0.12 5.0e-10 4.6e-10 4.4e-09 3.2e-10

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density3.76.89.5-1.9-3.12.81.92.23.0-2.8-2.82.82.62.6-3.1-2.9-2.62.81.9-2.42.72.9-1.92.3
Area under the delay curve0.10.21.20.3-0.60.3-0.20.10.2-0.2-0.20.40.20.2-0.9-0.2-0.10.2-0.1-0.00.41.10.20.1
BMI with tail0.41.33.41.81.0-1.3-1.4-1.6-0.91.11.1-1.1-1.2-1.10.80.91.1-1.1-1.01.3-0.9-0.90.9-1.0
BMI without tail0.42.44.52.11.5-1.6-1.9-1.8-1.41.51.5-1.4-1.5-1.51.51.41.5-1.6-1.41.4-1.2-1.51.3-1.4
Body weight2.410.413.83.73.3-3.3-3.5-3.4-3.13.33.2-3.1-3.3-3.33.03.23.3-3.2-3.33.2-2.8-2.83.3-3.2
Weight adjusted by age0.10.20.6-0.7-0.20.30.70.60.2-0.3-0.40.50.40.50.1-0.4-0.60.50.5-0.40.4-0.3-0.50.6
Bone surface1.73.45.7-0.8-2.32.10.91.22.4-2.0-2.02.21.81.8-2.4-2.2-1.82.20.9-1.62.22.1-0.81.4
Bone volume1.73.45.7-0.9-2.42.10.91.42.4-2.1-2.12.11.91.9-2.3-2.2-1.82.20.9-1.62.12.1-0.81.5
Breakpoint value in progressive ratio session0.61.01.8-0.6-0.90.90.51.10.8-1.0-1.01.21.01.0-1.3-1.0-1.11.20.8-0.91.11.3-0.81.2
Number of licking bursts0.00.10.70.8-0.4-0.0-0.6-0.60.30.00.00.1-0.2-0.1-0.6-0.20.20.1-0.40.40.20.40.3-0.2
Context. condit. distance diff. score0.00.00.1-0.30.20.10.30.20.0-0.1-0.10.00.10.10.0-0.0-0.0-0.00.3-0.10.10.0-0.30.0
Locomotion velocity, session 10.20.20.80.90.2-0.1-0.8-0.40.00.20.2-0.3-0.2-0.20.20.10.3-0.2-0.90.3-0.2-0.30.9-0.3
Locomotion distance, session 11.11.42.7-0.3-1.51.50.40.81.7-1.4-1.41.31.21.2-1.5-1.5-1.11.30.3-1.01.21.6-0.30.8
Locomotion velocity, session 20.30.30.50.60.6-0.5-0.6-0.7-0.50.60.6-0.6-0.6-0.60.50.60.7-0.7-0.40.6-0.6-0.30.4-0.7
Locomotion distance, session 20.00.00.20.50.00.0-0.5-0.20.10.00.0-0.1-0.1-0.10.1-0.00.1-0.0-0.30.1-0.20.00.3-0.2
Locomotion velocity, session 30.91.01.7-1.3-0.70.91.31.10.8-1.0-1.00.91.01.1-0.7-1.0-1.21.01.2-1.10.80.7-1.21.3
Locomotion distance, session 30.60.61.0-0.5-0.90.90.40.61.0-0.9-0.90.90.80.9-1.0-1.0-0.80.80.5-0.80.70.9-0.40.8
Stereotopy head waving bouts, day 32.32.83.6-1.9-1.41.61.91.81.5-1.6-1.61.61.71.7-1.3-1.6-1.81.61.9-1.81.71.3-1.91.8
Stereotopy head waving duration, day 30.30.40.7-0.8-0.20.40.80.80.3-0.5-0.50.50.60.6-0.2-0.5-0.70.50.8-0.70.50.3-0.90.8
Locomotion velocity, session 70.91.01.6-0.3-1.31.00.30.71.2-1.1-1.11.31.01.1-0.9-1.2-1.11.20.3-0.91.20.9-0.31.0
Locomotion distance, session 70.10.20.90.9-0.10.1-1.0-0.30.3-0.1-0.20.40.00.10.1-0.3-0.10.4-0.80.00.3-0.00.70.0
Stereotopy head waving bouts, day 70.00.10.2-0.5-0.30.10.5-0.10.1-0.1-0.1-0.10.10.1-0.2-0.1-0.1-0.10.4-0.10.10.2-0.50.1
Stereotopy head waving duration, day 70.60.72.0-1.4-0.70.61.40.80.5-0.7-0.70.50.70.7-0.6-0.6-0.70.51.2-0.80.70.6-1.20.8
Locomotion velocity, session 80.30.30.5-0.6-0.30.60.60.70.5-0.6-0.60.70.60.6-0.1-0.5-0.60.60.5-0.70.60.1-0.50.5
Locomotion distance, session 80.20.30.5-0.4-0.50.70.30.40.7-0.6-0.60.60.60.5-0.5-0.6-0.50.60.4-0.50.60.7-0.40.3
Degree of sensitization distance1.01.12.01.40.9-1.0-1.3-1.2-0.91.01.0-0.8-1.0-1.01.00.91.0-0.8-1.21.0-0.7-1.01.2-1.1
Degree of sensitization stereotypy0.20.20.5-0.00.2-0.50.0-0.6-0.50.50.5-0.7-0.5-0.50.30.50.5-0.7-0.00.5-0.5-0.2-0.1-0.4
Conditioned locomotion3.33.95.1-2.2-1.92.02.22.11.8-1.9-1.91.92.01.9-1.7-1.8-1.91.82.2-2.01.81.9-2.21.9
Cocaine response after cond. corrected0.30.51.4-0.1-0.90.80.10.40.9-0.8-0.80.80.70.7-0.9-0.8-0.60.90.1-0.50.91.2-0.10.5
Cocaine response after cond. not corrected1.01.42.8-0.8-1.61.30.80.91.4-1.3-1.21.21.21.1-1.5-1.3-1.11.20.8-0.91.31.7-0.80.9
Cocaine response before conditioning1.92.34.3-2.0-1.61.52.11.61.3-1.4-1.41.11.51.4-1.3-1.3-1.41.12.1-1.51.21.1-2.11.3
Saline control response0.81.12.2-1.4-0.91.01.41.00.9-1.0-1.00.91.01.0-0.7-0.9-1.00.91.4-1.10.90.7-1.50.9
Bone: connectivity density3.75.88.5-1.7-2.82.61.72.02.8-2.6-2.62.62.42.5-2.9-2.7-2.42.61.8-2.22.62.8-1.72.3
Bone: cortical apparent density0.30.51.0-0.3-1.00.70.40.40.8-0.7-0.70.70.60.6-1.0-0.8-0.60.80.4-0.50.71.0-0.40.5
Bone: cortical area0.40.61.30.2-1.00.9-0.10.21.2-0.8-0.80.90.70.7-1.1-1.0-0.60.9-0.1-0.51.01.00.10.4
Bone: cortical porosity1.61.73.3-1.8-1.21.31.81.51.1-1.2-1.21.01.31.2-1.2-1.1-1.21.01.7-1.41.00.9-1.61.3
Bone: cortical porosity1.51.62.3-1.5-1.21.31.51.51.2-1.3-1.31.11.31.3-1.3-1.2-1.31.11.4-1.41.10.9-1.31.3
Bone: cortical thickness0.10.10.40.6-0.1-0.1-0.5-0.70.20.10.1-0.2-0.3-0.3-0.20.00.4-0.2-0.60.4-0.20.20.5-0.5
Bone: cortical thickness1.11.31.9-0.5-1.31.30.60.91.4-1.2-1.21.31.21.2-1.4-1.3-1.11.40.6-1.11.21.4-0.61.1
Bone: cortical tissue density0.20.30.7-0.2-0.90.60.20.30.7-0.6-0.60.60.50.5-0.8-0.6-0.40.60.3-0.30.50.8-0.30.4
Condit. Reinf. active minus inactive responses0.91.01.91.30.7-1.0-1.4-1.2-0.81.00.9-0.8-1.0-1.00.70.81.0-0.8-1.31.2-0.9-0.61.3-0.9
Condit. Reinf. active-inactive response ratio1.01.12.31.40.8-1.0-1.5-1.0-0.91.01.0-0.8-1.0-0.90.70.90.9-0.8-1.41.1-0.9-0.71.4-0.8
Condit. Reinf. active responses0.10.10.50.2-0.60.3-0.2-0.10.4-0.3-0.30.30.20.2-0.6-0.3-0.10.2-0.10.00.30.70.10.1
Condit. Reinf. inactive responses1.31.72.6-1.1-1.61.41.11.01.5-1.4-1.41.21.31.3-1.5-1.4-1.21.21.3-1.21.41.6-1.31.1
Incentive salience index mean0.10.10.40.6-0.3-0.0-0.6-0.30.10.00.00.2-0.1-0.1-0.3-0.10.10.1-0.50.3-0.00.30.6-0.1
Condit. Reinf. lever presses0.50.71.4-0.3-1.20.90.40.71.0-0.9-0.90.90.80.8-1.1-0.9-0.80.90.5-0.60.81.2-0.40.7
Condit. Reinf. active minus inactive responses3.75.68.8-2.9-2.02.23.02.42.1-2.2-2.22.12.32.3-2.2-2.2-2.32.02.9-2.32.02.3-2.92.4
Condit. Reinf. active-inactive response ratio1.21.95.0-2.2-0.91.12.21.21.0-1.1-1.10.81.21.2-1.1-1.0-1.10.82.2-1.20.91.1-2.21.2
Condit. Reinf. active responses3.34.75.5-2.3-2.12.02.32.22.0-2.1-2.12.12.22.2-2.1-2.1-2.32.02.3-2.12.02.2-2.32.3
Condit. Reinf. inactive responses1.21.72.5-0.5-1.51.30.51.31.4-1.4-1.41.61.41.4-1.5-1.4-1.51.50.5-1.21.51.5-0.51.4
Condit. Reinf. lever presses2.03.03.8-1.9-1.61.72.01.71.6-1.7-1.71.81.71.7-1.7-1.6-1.61.71.9-1.71.61.9-1.91.5
Condit. Reinf. lever reinforcers received3.14.45.6-2.3-2.02.02.42.11.9-2.0-2.02.02.12.1-2.0-2.0-2.21.92.3-2.11.92.1-2.32.2
Conditioned reinforcement - actives0.83.16.3-2.3-0.91.62.32.51.1-1.6-1.61.81.81.7-0.6-1.3-1.91.82.2-2.31.70.4-2.01.9
Conditioned reinforcement - inactives1.64.46.6-2.0-2.62.22.32.22.1-2.1-2.12.02.12.1-2.1-2.1-2.11.92.1-1.72.11.7-2.12.0
Conditioned locomotion0.60.92.4-1.30.20.51.41.60.1-0.6-0.61.00.80.80.6-0.4-1.00.81.3-1.40.7-1.0-1.21.0
Patch foraging indifference point 0 sec0.20.71.10.90.6-1.0-0.8-0.9-0.80.90.8-1.0-0.9-0.80.60.70.7-0.8-0.80.9-1.1-0.90.8-0.7
Patch foraging indifference point AUC0.51.22.6-0.2-1.41.30.30.61.6-1.3-1.31.31.11.1-1.4-1.4-1.01.20.6-1.21.21.1-0.50.9
Delay disc. indifference point, 0s delay3.33.75.52.31.5-1.8-2.4-1.9-1.91.91.9-1.8-2.0-2.01.32.02.1-1.8-2.12.1-1.7-1.12.2-2.2
Delay disc. indifference point, 16s delay0.10.11.0-0.0-0.40.20.30.10.2-0.2-0.20.20.20.2-0.7-0.2-0.10.00.2-0.10.21.0-0.10.2
Delay disc. indifference point, 2s delay0.20.20.50.50.3-0.4-0.7-0.5-0.40.40.4-0.4-0.5-0.50.20.40.5-0.4-0.70.5-0.2-0.20.7-0.6
Delay disc. indifference point, 24s delay0.71.15.2-0.8-1.41.01.01.00.9-0.9-0.91.00.90.9-1.8-0.8-0.80.90.4-0.70.92.3-0.30.8
Delay disc. indifference point, 4s delay0.10.10.40.6-0.30.0-0.6-0.20.1-0.0-0.00.1-0.0-0.0-0.2-0.10.00.0-0.20.10.20.30.2-0.1
Delay disc. indifference point, 8s delay0.10.10.80.0-0.40.20.00.20.1-0.1-0.10.30.10.1-0.8-0.1-0.10.2-0.0-0.00.20.90.10.0
Indifference point function ln k0.00.10.8-0.90.00.20.70.7-0.0-0.2-0.20.20.30.20.0-0.1-0.30.30.5-0.30.30.0-0.40.3
Indifference point function log k0.00.10.8-0.90.00.20.70.7-0.0-0.2-0.20.20.30.20.0-0.1-0.30.30.5-0.30.30.0-0.40.3
Patch foraging total patch changes 0 sec0.20.61.00.90.5-0.9-0.8-1.0-0.80.90.8-0.9-0.8-0.80.50.70.7-0.7-0.70.9-1.0-0.80.6-0.7
Patch foraging total patch changes 12 sec1.11.52.31.51.0-1.3-1.4-1.4-1.11.21.2-1.3-1.2-1.21.01.11.2-1.2-1.11.2-1.4-1.31.1-1.2
Patch foraging total patch changes 18 sec0.10.20.80.90.1-0.4-0.7-0.8-0.20.40.3-0.3-0.4-0.40.30.20.4-0.2-0.60.3-0.4-0.60.5-0.4
Patch foraging total patch changes 24 sec0.41.22.61.11.2-1.2-0.9-1.2-1.01.11.1-1.1-1.1-1.11.31.01.1-1.0-0.61.0-1.3-1.60.6-1.1
Patch foraging total patch changes 6 sec0.20.31.01.00.1-0.6-0.9-0.8-0.30.50.4-0.5-0.5-0.40.10.30.4-0.5-0.80.5-0.8-0.50.8-0.3
Patch foraging time to switch 0 sec0.00.00.10.10.2-0.3-0.1-0.3-0.30.20.2-0.2-0.2-0.10.20.10.1-0.2-0.10.30.00.2-0.00.0
Patch foraging water rate 0 sec0.00.10.5-0.7-0.00.30.60.60.1-0.2-0.20.20.30.2-0.0-0.1-0.20.30.7-0.50.0-0.3-0.50.1
Patch foraging water rate 12 sec0.41.62.40.61.6-1.3-0.7-0.9-1.51.31.4-1.4-1.3-1.31.61.51.3-1.2-0.71.0-1.5-1.60.8-1.3
Patch foraging water rate 18 sec0.20.51.1-0.41.0-0.70.1-0.1-1.00.70.8-1.0-0.6-0.71.01.00.7-0.9-0.20.5-0.7-1.00.3-0.7
Patch foraging water rate 24 sec1.62.33.90.92.0-1.7-0.9-1.1-2.01.71.7-1.5-1.6-1.61.91.91.5-1.4-0.91.2-1.7-1.61.0-1.4
Patch foraging water rate 6 sec0.91.32.00.51.4-1.1-0.7-0.7-1.41.21.2-1.4-1.1-1.21.41.41.3-1.4-0.70.9-1.2-1.40.8-1.3
Seeking ratio, delayed vs. immediate footshock0.00.10.70.00.3-0.1-0.1-0.0-0.10.10.1-0.2-0.1-0.10.70.1-0.0-0.1-0.0-0.1-0.0-0.8-0.0-0.1
Distance traveled before self-admin0.00.00.1-0.10.00.00.0-0.1-0.00.10.1-0.1-0.1-0.20.10.20.3-0.2-0.20.1-0.1-0.00.3-0.4
Distance traveled after self-admin1.62.83.41.71.7-1.5-1.8-1.8-1.41.61.6-1.6-1.7-1.71.61.61.8-1.6-1.81.5-1.6-1.41.8-1.8
Extensor digitorum longus weight4.417.618.7-4.1-4.34.24.24.04.2-4.2-4.24.24.24.2-4.3-4.2-4.14.14.3-4.24.34.3-4.34.0
Bone: elastic displacement0.70.91.6-0.9-0.80.90.91.30.7-0.9-0.91.00.90.9-0.9-0.8-1.01.11.0-0.90.70.9-0.91.0
Bone: elastic work0.81.11.6-0.6-1.11.10.61.11.1-1.1-1.11.21.01.1-1.2-1.1-1.11.20.7-1.01.11.2-0.61.0
Bone: endosteal estimation0.51.12.2-0.0-1.21.20.00.81.3-1.1-1.21.41.01.1-1.2-1.3-1.11.40.1-1.01.51.1-0.11.0
Bone: endosteal perimeter0.20.51.10.2-0.80.7-0.20.40.8-0.7-0.70.90.60.6-0.7-0.8-0.70.9-0.1-0.61.00.80.20.5
Epididymis fat weight10.955.262.37.77.9-7.9-7.5-7.3-7.87.77.6-7.2-7.6-7.57.57.57.3-7.1-7.07.3-7.2-7.46.9-7.0
Delta time in closed arm before/after self-admin0.00.00.20.20.2-0.00.1-0.20.1-0.0-0.10.20.00.0-0.1-0.1-0.10.2-0.0-0.00.40.20.10.1
Delta time in open arm before/after self-admin0.10.10.2-0.2-0.40.30.30.40.3-0.4-0.40.40.40.4-0.3-0.4-0.50.40.3-0.40.30.3-0.40.5
Diff in mean of infusions in LGA sessions0.00.00.20.2-0.30.1-0.20.10.1-0.1-0.10.20.10.1-0.3-0.2-0.20.40.1-0.10.00.1-0.20.2
Delay discount exponential model param0.30.42.00.10.9-0.6-0.1-0.5-0.50.50.5-0.7-0.5-0.51.10.50.5-0.6-0.20.4-0.7-1.40.1-0.4
Extinction: sum of active levers before priming0.20.41.0-0.3-0.70.50.50.40.5-0.5-0.50.60.50.6-0.9-0.6-0.50.60.7-0.40.51.0-0.80.5
Active lever presses in extinction session 60.80.81.9-0.9-0.50.80.71.40.6-0.9-0.91.11.01.0-0.3-0.8-1.11.01.1-1.20.80.1-1.01.3
Bone: final force0.10.10.30.4-0.20.3-0.30.00.5-0.3-0.30.60.20.2-0.3-0.4-0.20.5-0.3-0.20.50.30.40.1
Bone: final moment0.10.20.30.4-0.30.4-0.40.00.6-0.4-0.40.60.30.3-0.4-0.5-0.30.5-0.4-0.30.50.40.40.2
Food consumed during 24 hour testing period0.10.20.3-0.3-0.50.40.30.20.6-0.4-0.40.30.40.4-0.5-0.5-0.30.30.3-0.30.40.4-0.40.3
Glucose0.20.40.80.70.6-0.6-0.5-0.7-0.50.60.6-0.5-0.6-0.60.70.50.6-0.5-0.60.6-0.5-0.90.7-0.7
Heart weight3.15.06.22.32.0-2.1-2.2-2.4-2.02.22.2-2.4-2.2-2.32.22.12.4-2.5-2.22.3-2.0-2.22.2-2.4
Delay discount hyperbolic model param0.20.21.3-0.10.7-0.40.1-0.3-0.40.40.4-0.5-0.3-0.40.90.40.3-0.4-0.00.2-0.6-1.2-0.1-0.3
Intermittent access intake day 1-15 change0.00.21.0-0.6-0.00.40.70.50.2-0.3-0.30.40.40.30.1-0.1-0.20.30.8-1.00.4-0.3-0.50.3
Intermittent access intake escalation0.00.10.4-0.30.20.10.40.1-0.1-0.00.00.10.0-0.00.20.20.1-0.00.4-0.60.1-0.5-0.2-0.0
Intermittent access intake escalation 20.00.00.3-0.10.00.10.3-0.20.1-0.0-0.0-0.10.0-0.10.30.00.2-0.20.2-0.40.2-0.50.0-0.1
Intermitt. access day 1 inactive lever presses0.11.93.2-1.6-1.21.31.81.51.3-1.3-1.31.21.41.4-1.1-1.4-1.41.31.7-1.21.20.8-1.81.4
Intermitt. access day 15 inactive lever presses1.26.69.5-2.1-2.72.82.42.33.1-2.8-2.82.52.72.7-2.0-3.0-2.72.52.4-2.52.61.9-2.52.6
Intermitt. access escalation Index0.30.92.71.60.8-0.9-1.5-1.6-0.40.80.7-0.9-0.8-0.80.90.50.9-0.8-1.10.8-1.0-0.80.9-0.7
Intermittent access day 1 total infusions1.85.36.6-2.5-2.32.32.42.62.2-2.3-2.32.32.42.4-1.9-2.3-2.52.22.4-2.12.02.0-2.42.4
Intermittent access day 15 total infusions0.92.33.1-1.8-1.31.61.71.71.4-1.6-1.51.51.61.5-1.0-1.4-1.51.41.7-1.81.31.0-1.61.5
Intermittent access terminal intake (last 3 days)1.93.34.7-2.1-1.51.92.12.01.7-1.8-1.81.81.91.8-1.3-1.7-1.81.62.2-2.01.61.2-2.01.8
Intermittent access total infusions2.83.35.3-2.3-1.51.72.22.31.4-1.7-1.71.91.81.8-1.3-1.6-1.91.72.2-1.91.61.2-2.01.9
Intermittent access day 1 locomotion1.42.64.0-1.7-1.41.51.91.81.4-1.6-1.51.61.61.6-1.5-1.5-1.71.41.9-1.41.31.4-2.01.6
Intermittent access day 15 total locomotion0.10.51.3-0.8-0.70.61.10.80.5-0.6-0.60.90.60.7-0.5-0.6-0.70.61.1-0.60.70.1-1.10.7
Intermittent access total locomotion0.70.82.1-1.1-0.60.61.41.20.3-0.7-0.71.10.80.8-0.4-0.6-1.00.81.4-0.80.70.1-1.40.9
Intermittent access standard deviation0.31.72.3-1.4-1.31.31.51.41.2-1.3-1.31.31.31.3-1.1-1.3-1.41.31.4-1.31.20.9-1.31.3
Left kidney weight0.00.00.10.10.3-0.2-0.3-0.1-0.30.20.2-0.1-0.2-0.20.20.20.1-0.1-0.40.1-0.10.00.3-0.1
Right kidney weight0.32.12.91.51.2-1.5-1.5-1.5-1.51.51.5-1.6-1.5-1.50.81.51.6-1.6-1.61.7-1.3-0.71.6-1.5
Cocaine induced anxiety0.10.30.5-0.2-0.60.50.70.30.6-0.5-0.60.50.50.5-0.4-0.6-0.50.50.3-0.50.50.3-0.50.5
Post-drug Anxiety1.31.52.41.50.9-1.2-1.3-1.4-1.11.21.2-1.2-1.2-1.20.91.11.3-1.2-1.51.3-1.2-1.11.4-1.3
Baseline Anxiety2.44.06.42.11.9-2.0-2.5-1.9-2.02.02.0-1.9-2.0-2.01.62.01.9-1.9-2.02.1-2.1-1.72.1-2.0
Tail length0.31.72.41.21.4-1.2-1.5-1.1-1.41.31.3-1.2-1.2-1.31.51.41.3-1.4-1.51.0-1.0-1.41.5-1.3
Length with tail1.77.610.12.43.2-2.8-2.6-2.3-3.02.82.8-2.7-2.7-2.83.03.02.8-2.7-2.82.4-2.5-2.82.9-2.7
Length without tail0.42.02.81.41.7-1.4-1.4-1.2-1.51.41.4-1.3-1.4-1.41.51.51.4-1.2-1.61.4-1.2-1.31.7-1.4
Times rat made contact with spout1.82.03.2-1.3-1.61.41.31.21.5-1.4-1.41.51.41.4-1.7-1.5-1.31.51.3-1.21.51.8-1.31.2
Lifetime Intake2.93.66.0-2.3-1.51.82.22.41.5-1.8-1.82.01.91.9-1.3-1.7-2.11.92.2-2.01.81.2-2.12.1
Liver weight, left3.86.67.62.72.4-2.5-2.8-2.5-2.52.62.6-2.6-2.6-2.62.52.52.5-2.6-2.72.6-2.5-2.42.7-2.5
Liver weight, right9.516.519.23.84.3-4.2-3.7-3.9-4.24.24.2-4.3-4.1-4.14.44.24.1-4.4-3.64.1-4.1-4.23.5-3.9
Locomotor activity0.30.51.31.20.4-0.8-0.9-0.9-0.70.70.7-0.6-0.8-0.70.00.60.7-0.6-0.81.0-0.7-0.10.8-0.6
Locomotor testing distance0.10.20.60.1-0.40.20.20.10.4-0.3-0.40.40.30.4-0.8-0.5-0.40.50.2-0.20.30.8-0.30.6
Locomotor testing rearing0.41.32.3-1.0-0.70.81.31.30.8-1.0-1.01.31.11.2-1.0-1.0-1.41.51.3-1.31.10.9-1.31.5
Locomotion in novel chamber0.20.21.40.11.0-0.5-0.30.1-0.60.40.3-0.2-0.2-0.21.20.50.1-0.2-0.2-0.3-0.4-0.9-0.00.1
Locomotion in novel chamber post-restriction1.44.35.71.92.2-2.3-1.7-2.0-2.42.22.2-2.2-2.1-2.12.32.22.0-2.0-1.72.1-2.3-2.01.6-1.8
Fecal boli incidents, locomotor time 10.10.30.7-0.9-0.40.60.70.70.6-0.6-0.60.40.60.6-0.4-0.5-0.50.30.8-0.70.40.5-0.80.6
Change in fecal boli incidents, locomotor task4.24.56.72.22.0-2.2-2.6-2.1-2.12.12.1-2.0-2.1-2.11.92.12.0-1.9-2.42.2-2.1-2.02.3-2.1
Time >=10cm from walls, locomotor time 10.10.10.20.10.2-0.2-0.1-0.0-0.30.30.3-0.3-0.3-0.30.00.40.3-0.1-0.20.3-0.40.30.2-0.4
Bouts of movement, locomotor time 11.31.73.0-1.3-1.11.31.50.91.5-1.4-1.41.61.31.3-1.3-1.4-1.21.21.0-1.31.71.5-1.01.2
Total resting periods, locomotor time 11.72.03.3-1.3-1.31.51.31.01.6-1.5-1.51.71.41.4-1.4-1.6-1.41.31.0-1.41.81.5-1.01.3
Rest time, locomotor task time 10.10.10.50.10.2-0.2-0.5-0.1-0.20.20.2-0.2-0.2-0.20.60.20.1-0.2-0.70.2-0.2-0.30.7-0.1
Distance moved, locomotor task time 10.41.11.81.31.2-1.1-0.9-1.0-1.11.11.1-1.2-1.1-1.10.91.11.2-1.2-0.71.2-1.2-0.70.7-1.0
Vertical activity count, locomotor time 10.10.61.21.10.9-0.7-0.8-0.7-0.70.70.7-0.7-0.7-0.80.30.80.8-0.8-0.60.9-0.9-0.20.7-0.8
Time >=10cm from walls, locomotor time 20.10.40.8-0.5-0.60.70.70.90.4-0.6-0.60.70.60.50.0-0.4-0.60.70.7-0.70.70.2-0.80.4
Bouts of movement, locomotor time 20.00.10.4-0.10.4-0.20.2-0.7-0.20.30.3-0.2-0.4-0.40.20.30.4-0.2-0.40.3-0.1-0.10.4-0.6
Total resting periods, locomotor time 20.00.00.3-0.40.10.10.5-0.40.2-0.1-0.00.2-0.0-0.0-0.1-0.10.10.2-0.1-0.00.30.10.1-0.3
Rest time, locomotor task time 20.81.32.2-1.0-1.51.20.80.81.3-1.2-1.21.21.11.2-1.4-1.3-1.21.20.7-1.01.21.3-0.71.1
Distance moved, locomotor task time 20.81.01.81.31.2-1.0-0.9-0.7-1.21.11.1-1.0-1.0-1.01.31.11.0-1.1-0.50.9-1.0-1.10.5-0.9
Vertical activity count, locomotor time 20.20.51.10.70.9-0.7-0.7-0.3-0.80.70.7-0.6-0.7-0.71.10.80.7-0.6-0.60.5-0.6-1.00.6-0.7
Light reinforcement 11.35.78.5-1.9-2.82.52.01.62.9-2.5-2.52.52.42.4-2.9-2.7-2.32.41.8-2.22.62.6-1.82.2
Light reinforcement 21.73.86.2-1.7-2.42.21.61.42.4-2.1-2.11.91.91.9-2.5-2.2-1.82.01.5-1.72.22.1-1.41.7
Bone: marrow area0.51.12.2-0.1-1.21.10.10.81.3-1.1-1.21.41.01.1-1.2-1.3-1.11.40.1-1.01.51.1-0.11.0
Bone: maximum diameter0.81.52.7-0.1-1.51.30.20.61.6-1.3-1.41.61.21.2-1.7-1.5-1.21.60.1-1.11.71.5-0.11.0
Bone: maximum force0.10.20.40.0-0.30.5-0.00.30.6-0.5-0.50.60.40.4-0.4-0.5-0.40.6-0.0-0.40.60.40.00.3
Bone: maximum moment0.10.30.5-0.0-0.50.6-0.00.40.7-0.6-0.60.70.50.5-0.6-0.6-0.50.70.0-0.50.70.60.00.4
Mean time between licks in bursts0.63.84.51.91.9-2.0-2.0-1.9-1.92.02.0-2.1-2.0-2.01.82.02.0-2.0-1.92.0-2.1-1.71.9-1.9
Mean num. licks in bursts0.10.41.4-1.2-0.30.60.90.80.4-0.5-0.50.50.60.6-0.2-0.4-0.60.40.8-0.70.40.4-0.70.5
Cd content in liver0.00.00.10.30.00.00.0-0.20.1-0.0-0.00.1-0.00.00.0-0.1-0.00.1-0.0-0.00.00.1-0.0-0.0
Co content in liver5.46.38.0-2.2-2.82.72.12.42.7-2.6-2.62.72.52.5-2.8-2.6-2.42.72.1-2.52.72.7-2.12.2
Cu content in liver0.10.10.3-0.3-0.40.40.40.60.3-0.3-0.30.20.40.4-0.3-0.3-0.30.30.4-0.40.30.3-0.40.4
Fe content in liver1.01.32.7-1.0-0.81.11.01.60.9-1.1-1.21.01.31.3-0.7-1.1-1.41.21.0-1.30.90.7-1.01.6
K content in liver0.30.30.70.7-0.60.5-0.8-0.10.8-0.5-0.50.60.40.4-0.5-0.7-0.30.5-0.8-0.20.70.60.80.2
Mg content in liver0.30.30.70.7-0.70.5-0.7-0.20.8-0.5-0.50.60.40.4-0.6-0.7-0.30.6-0.7-0.20.70.80.70.2
Mn content in liver0.10.10.40.60.00.1-0.6-0.20.3-0.2-0.20.40.10.20.0-0.4-0.30.5-0.6-0.10.40.10.60.3
Na content in liver0.50.61.1-0.7-0.70.90.61.00.8-0.8-0.80.70.80.8-0.6-0.7-0.70.60.6-0.90.70.6-0.50.7
Rb content in liver0.10.10.30.5-0.1-0.1-0.6-0.20.10.0-0.00.0-0.00.0-0.0-0.1-0.00.1-0.60.10.00.20.60.1
Se content in liver0.10.10.50.10.6-0.40.0-0.1-0.40.30.3-0.2-0.2-0.20.70.20.1-0.1-0.00.1-0.2-0.7-0.0-0.0
Sr content in liver0.10.10.30.30.3-0.2-0.2-0.2-0.40.30.4-0.4-0.3-0.40.30.50.5-0.5-0.30.3-0.4-0.20.3-0.5
Zn content in liver1.11.32.61.60.9-1.0-1.5-1.1-0.91.01.0-1.0-1.0-1.11.00.91.1-0.9-1.51.0-0.9-1.01.5-1.1
Bone: minimum diameter0.20.41.61.20.1-0.3-1.2-0.7-0.10.30.3-0.1-0.4-0.40.20.10.4-0.1-1.10.5-0.1-0.41.2-0.5
Time in familiar zone, hab. session 10.80.91.81.30.9-0.9-1.3-1.0-0.70.80.8-0.7-0.9-0.81.00.70.8-0.7-1.30.8-0.7-1.01.2-0.8
Time in novel zone, hab. session 10.30.30.9-0.10.9-0.80.2-0.2-0.90.70.7-0.7-0.5-0.50.90.70.4-0.50.00.4-0.7-0.8-0.0-0.3
Total zone transitions, hab. session 10.10.10.2-0.4-0.40.40.30.20.4-0.4-0.30.30.30.3-0.3-0.3-0.30.50.4-0.30.40.5-0.40.1
Total locomotion distance, hab. session 10.10.20.3-0.2-0.50.50.10.30.5-0.5-0.50.40.40.4-0.4-0.5-0.40.50.2-0.30.60.4-0.20.2
Locomotion velocity, hab. session 10.81.11.8-0.8-1.41.30.70.91.3-1.2-1.11.01.11.0-1.3-1.2-1.01.20.8-0.91.11.2-0.70.8
Time in familiar zone, hab. session 20.00.00.0-0.10.20.00.1-0.20.1-0.0-0.00.20.00.00.0-0.1-0.00.20.1-0.10.2-0.0-0.10.0
Time in novel zone, hab. session 20.50.50.70.80.6-0.7-0.8-0.4-0.80.70.7-0.8-0.7-0.70.60.80.6-0.8-0.80.7-0.8-0.60.8-0.6
Total zone transitions, hab. session 20.10.10.30.3-0.40.2-0.3-0.20.4-0.2-0.20.20.10.1-0.4-0.3-0.10.3-0.4-0.00.30.60.4-0.0
Total locomotion distance, hab. session 20.10.10.4-0.0-0.60.4-0.0-0.10.6-0.4-0.40.30.30.3-0.6-0.5-0.20.3-0.1-0.10.40.60.10.1
Locomotion velocity, hab. session 20.20.30.7-0.2-0.80.60.20.10.8-0.6-0.60.50.50.5-0.8-0.7-0.40.50.2-0.30.60.9-0.10.3
Novel to familiar place preference ratio0.91.11.41.00.9-1.1-1.0-1.2-1.11.11.1-1.0-1.1-1.10.71.11.1-1.1-1.11.2-1.1-0.81.1-1.2
Novelty place preference1.31.72.01.21.2-1.4-1.2-1.4-1.41.41.4-1.3-1.4-1.41.01.41.4-1.3-1.31.4-1.4-1.11.3-1.4
Time in novel zone, NPP test1.51.92.21.31.4-1.5-1.2-1.4-1.51.41.4-1.4-1.4-1.41.11.41.4-1.4-1.31.4-1.5-1.21.3-1.4
Total zone transitions, NPP test1.21.82.5-1.2-1.51.51.21.21.5-1.4-1.41.21.41.4-1.5-1.4-1.31.31.3-1.31.21.6-1.21.2
Total locomotion distance, NPP test1.82.53.0-1.7-1.71.71.51.41.7-1.6-1.61.41.61.6-1.6-1.6-1.51.51.6-1.51.51.7-1.51.4
Locomotion velocity, NPP test2.84.15.2-1.9-2.32.11.81.72.2-2.1-2.12.02.02.0-2.2-2.1-1.92.01.9-1.92.02.3-1.81.8
Intraocular pressure5.28.59.82.92.9-3.1-2.8-3.1-3.03.03.0-2.9-3.0-3.02.52.93.0-2.8-3.03.1-3.0-2.33.0-2.8
Delta distance traveled before/after self-admin1.82.02.61.61.6-1.4-1.6-1.6-1.21.41.3-1.5-1.4-1.41.61.21.4-1.3-1.41.2-1.4-1.61.3-1.3
Delta ambulatory time before/after self-admin0.20.41.01.00.7-0.5-1.0-0.8-0.30.50.5-0.6-0.5-0.50.60.40.6-0.4-0.70.4-0.5-0.60.6-0.5
Parametrial fat weight12.730.038.75.85.1-5.4-5.3-6.2-4.95.45.4-5.4-5.6-5.65.25.25.7-5.6-5.65.5-5.2-5.15.6-5.9
Pavlov. Cond. lever latency1.41.73.10.81.8-1.5-0.9-1.0-1.61.41.4-1.5-1.3-1.31.61.51.3-1.4-0.81.1-1.4-1.60.8-1.2
Pavlov. Cond. magazine entry latency0.00.10.2-0.0-0.40.30.10.00.4-0.3-0.30.20.20.2-0.2-0.3-0.20.2-0.1-0.10.20.30.10.2
Pavlov. Cond. change in total contacts0.00.00.10.1-0.30.2-0.10.10.2-0.2-0.20.10.10.1-0.2-0.2-0.10.1-0.2-0.00.10.30.20.1
Pavlov. Cond. index score0.50.61.4-0.2-1.20.90.40.41.1-0.9-0.90.90.80.8-1.0-1.0-0.70.80.2-0.50.81.1-0.10.7
Pavlov. Cond. latency score0.50.61.4-0.2-1.20.90.40.41.1-0.9-0.90.90.70.8-1.0-1.0-0.70.80.1-0.50.81.1-0.10.6
Pavlov. Cond. lever contacts0.91.02.1-0.5-1.41.20.60.81.3-1.1-1.11.21.01.0-1.3-1.2-0.91.10.4-0.81.11.3-0.40.9
Pavlov. Cond. magazine entry number0.30.40.80.30.9-0.7-0.4-0.4-0.90.70.7-0.6-0.6-0.60.60.80.6-0.6-0.20.5-0.6-0.70.2-0.6
Pavlov. Cond. intertrial magazine entries1.41.62.6-1.1-1.31.31.21.41.2-1.2-1.21.11.31.3-1.4-1.2-1.21.01.6-1.21.21.4-1.61.3
Pavlov. Cond. lever-magazine prob. diff.1.01.32.4-0.6-1.61.30.80.81.4-1.2-1.21.21.11.2-1.3-1.3-1.11.20.6-0.91.21.5-0.51.1
Pavlov. Cond. response bias1.11.32.2-0.8-1.51.30.91.01.4-1.3-1.31.21.21.2-1.2-1.3-1.11.10.7-1.01.11.4-0.61.1
Pavlov. Cond. lever latency1.52.12.51.51.4-1.4-1.5-1.4-1.41.41.4-1.6-1.4-1.41.51.41.4-1.6-1.51.4-1.5-1.51.5-1.3
Pavlov. Cond. magazine entry latency0.20.30.6-0.5-0.50.60.50.50.6-0.6-0.60.80.60.6-0.5-0.6-0.60.80.6-0.60.60.2-0.60.4
Pavlov. Cond. change in total contacts0.51.11.8-1.1-1.01.01.11.00.9-1.0-1.01.31.01.0-1.2-1.0-1.01.31.2-1.01.01.2-1.20.9
Pavlov. Cond. index score1.11.72.3-1.3-1.21.31.31.21.2-1.3-1.31.51.21.2-1.3-1.2-1.31.51.3-1.31.31.1-1.31.1
Pavlov. Cond. latency score1.01.72.4-1.3-1.21.31.31.21.3-1.3-1.31.61.31.2-1.2-1.2-1.21.51.4-1.31.31.1-1.41.1
Pavlov. Cond. lever contacts1.01.51.8-1.3-1.21.21.31.11.1-1.2-1.21.31.21.2-1.3-1.1-1.21.31.3-1.21.31.3-1.21.0
Pavlov. Cond. magazine entry number0.10.20.50.30.3-0.5-0.3-0.3-0.50.50.4-0.7-0.4-0.40.40.50.4-0.7-0.40.4-0.5-0.30.4-0.3
Pavlov. Cond. intertrial magazine entries2.45.26.12.22.3-2.4-2.2-2.3-2.42.42.4-2.4-2.3-2.32.12.32.3-2.5-2.22.3-2.3-2.02.2-2.1
Pavlov. Cond. lever-magazine prob. diff.0.71.11.6-1.0-1.01.11.00.91.0-1.0-1.01.31.01.0-1.1-1.0-1.01.31.0-1.01.10.9-1.00.9
Pavlov. Cond. response bias1.72.32.7-1.5-1.51.51.51.41.5-1.5-1.51.61.51.5-1.6-1.5-1.51.61.6-1.51.61.6-1.51.4
Time in closed arm before self-admin0.50.81.50.71.1-1.0-0.8-0.8-1.11.01.0-0.8-0.9-0.91.21.00.8-0.7-0.30.9-0.8-1.20.2-0.8
Time in closed arm after self-admin0.91.12.20.81.5-1.3-0.7-0.8-1.41.11.1-1.0-1.1-1.01.31.20.9-0.8-0.41.0-0.9-1.40.5-0.8
Time in open arm before self-admin0.10.10.4-0.1-0.60.30.1-0.00.3-0.2-0.20.10.10.1-0.6-0.2-0.0-0.00.1-0.00.20.7-0.00.1
Time in open arm after self-admin1.21.32.4-0.8-1.51.20.90.91.4-1.2-1.21.11.21.2-1.4-1.3-1.11.00.9-1.01.11.4-1.01.2
Bone: periosteal estimation0.71.62.8-0.1-1.61.40.10.81.7-1.4-1.41.61.21.2-1.5-1.5-1.21.50.2-1.11.71.4-0.11.0
Bone: periosteal perimeter0.30.51.10.0-1.00.80.00.31.0-0.8-0.80.90.70.7-0.9-0.9-0.60.90.0-0.61.01.00.00.5
Bone: post-yield work1.01.72.7-1.6-0.91.21.61.41.1-1.2-1.21.31.31.2-0.9-1.1-1.31.31.6-1.41.11.1-1.61.2
Progressive ratio test 1 active lever presses1.22.13.6-1.7-1.51.41.61.91.1-1.4-1.41.51.41.5-1.3-1.3-1.61.41.4-1.21.50.9-1.41.5
Progressive ratio test 1 breakpoint1.22.13.6-1.7-1.51.41.61.91.1-1.4-1.41.51.41.5-1.3-1.3-1.61.41.4-1.21.51.0-1.41.5
Progressive ratio test 1 inactive lever presses1.84.87.0-2.4-2.12.22.52.72.0-2.2-2.22.12.32.3-1.5-2.1-2.42.12.3-2.32.11.3-2.42.3
Progressive ratio test 2 active lever presses0.40.61.7-1.2-0.40.61.11.30.3-0.6-0.60.80.70.7-0.1-0.4-0.80.60.9-0.90.6-0.0-0.70.7
Progressive ratio test 2 breakpoint0.30.41.4-1.1-0.30.51.01.20.2-0.5-0.50.70.60.60.0-0.3-0.70.50.8-0.80.5-0.1-0.60.6
Progressive ratio test 2 inactive lever presses0.82.53.8-1.8-1.31.62.02.01.4-1.6-1.51.61.61.6-0.8-1.5-1.71.61.8-1.71.60.5-1.71.6
Incentive Sensitization - Responses0.10.20.7-0.6-0.10.50.50.70.3-0.4-0.40.40.50.40.1-0.3-0.40.30.5-0.80.2-0.0-0.30.3
Incentive Sensitization - Breakpoint0.00.10.4-0.40.00.30.30.50.2-0.3-0.30.30.30.20.3-0.1-0.20.20.4-0.70.0-0.2-0.20.2
Sum of active levers in priming session hrs 5-60.40.31.20.4-1.10.5-0.4-0.10.8-0.6-0.60.40.40.5-1.0-0.7-0.40.40.1-0.10.51.1-0.10.4
Progressive ratio0.00.00.30.30.2-0.2-0.50.0-0.10.10.10.0-0.1-0.00.20.0-0.00.00.00.0-0.0-0.50.00.1
Food seeking constrained by brief footshock4.35.48.6-2.7-2.12.32.52.91.9-2.3-2.22.12.42.4-1.8-2.1-2.42.32.7-2.62.01.5-2.52.4
Seeking ratio, punishment vs. effort0.30.61.3-1.1-0.90.81.10.90.7-0.8-0.70.50.80.7-0.9-0.6-0.70.60.7-0.70.51.0-0.70.6
Retroperitoneal fat weight21.998.0115.210.79.8-10.3-10.3-10.5-9.710.09.9-9.6-10.0-9.99.99.69.7-9.6-9.910.0-9.5-9.79.7-9.4
Reaction time number correct0.20.71.1-0.9-1.00.90.80.71.0-0.9-0.90.90.80.8-1.0-0.9-0.80.90.7-0.80.70.9-0.70.7
Reaction time mean minus median0.00.10.5-0.4-0.00.00.50.3-0.1-0.0-0.00.00.10.10.30.0-0.1-0.10.7-0.20.1-0.3-0.60.1
Reaction time mean minus median AUC0.00.10.10.00.2-0.30.1-0.1-0.30.30.3-0.3-0.2-0.20.30.30.2-0.30.20.1-0.2-0.4-0.2-0.2
Reaction time num false alarms0.20.30.80.8-0.5-0.3-0.7-0.90.10.20.2-0.2-0.3-0.2-0.6-0.10.3-0.1-0.90.7-0.30.50.8-0.3
Reaction time num false alarms AUC0.10.31.00.9-0.6-0.2-0.8-1.00.10.20.2-0.1-0.3-0.2-0.8-0.10.3-0.1-0.90.8-0.30.60.7-0.3
Reaction time trials correct on left0.20.71.1-0.9-1.00.90.80.71.0-0.9-0.90.90.80.8-1.0-0.9-0.80.90.7-0.80.70.9-0.70.7
Reaction time trials on left0.20.81.2-0.9-1.11.00.90.71.0-0.9-0.90.90.90.9-1.1-0.9-0.80.90.7-0.90.71.0-0.70.8
Reaction time mean0.71.62.21.11.0-1.2-1.2-1.1-1.31.31.3-1.3-1.3-1.41.11.41.4-1.5-1.11.4-1.2-1.31.1-1.4
Reaction time mean AUC0.61.32.01.00.9-1.1-1.0-1.0-1.21.21.2-1.2-1.2-1.21.01.31.3-1.4-1.01.3-1.1-1.21.0-1.3
Median of all reaction times1.21.92.61.41.0-1.3-1.4-1.3-1.41.41.4-1.4-1.4-1.51.11.51.6-1.6-1.31.5-1.3-1.31.4-1.6
Reaction time omissions0.00.10.40.2-0.60.1-0.00.00.3-0.2-0.20.20.20.2-0.3-0.3-0.30.20.1-0.10.20.1-0.10.3
Reaction time false alarm rate0.40.61.61.2-0.1-0.7-1.1-1.3-0.30.60.6-0.6-0.7-0.6-0.20.40.7-0.5-1.21.2-0.70.11.1-0.7
Reaction time premature initiation rate0.10.20.30.10.4-0.5-0.1-0.3-0.50.40.4-0.4-0.4-0.40.50.50.3-0.50.10.4-0.4-0.40.0-0.4
Reaction time premature initiations0.00.00.1-0.4-0.10.10.40.10.0-0.1-0.10.10.10.1-0.1-0.0-0.10.00.4-0.1-0.00.1-0.30.1
Std. dev. reaction times0.10.40.70.40.5-0.6-0.5-0.4-0.70.60.7-0.6-0.6-0.60.70.70.6-0.8-0.40.6-0.6-0.80.5-0.7
Reaction time trials completed0.20.81.2-0.9-1.11.00.90.71.0-0.9-0.90.90.90.9-1.1-0.9-0.80.90.7-0.90.71.0-0.70.8
Reaction time trials AUC0.31.01.4-1.1-1.11.11.00.91.1-1.0-1.01.01.01.0-1.2-1.0-0.91.00.9-1.00.81.1-0.90.9
Run reversals in cocaine runway, females0.00.10.3-0.20.2-0.1-0.00.1-0.30.20.2-0.4-0.1-0.20.20.30.2-0.3-0.10.2-0.50.00.2-0.2
Run reversals in cocaine runway, males0.10.10.5-0.7-0.00.30.50.50.1-0.2-0.20.10.30.3-0.3-0.1-0.30.30.4-0.30.10.6-0.30.2
Latency to leave start box in cocaine runway0.50.61.1-0.6-0.70.90.31.00.7-0.8-0.80.90.90.8-0.7-0.7-0.80.80.8-1.10.80.4-0.70.8
Latency to leave start box in cocaine runway, F0.20.30.8-0.2-0.90.50.00.40.5-0.5-0.50.50.50.5-0.9-0.5-0.40.40.6-0.50.50.6-0.60.5
Latency to leave start box in cocaine runway, M0.20.20.7-0.60.40.40.40.80.1-0.4-0.30.40.40.40.5-0.2-0.40.40.3-0.80.4-0.5-0.10.4
Std. dev. time between licks in bursts0.20.31.21.10.1-0.4-0.9-1.0-0.10.40.4-0.4-0.5-0.50.30.20.6-0.5-0.80.6-0.2-0.10.7-0.6
Total sessions with >9 infusions1.11.32.9-1.5-0.51.01.51.70.7-1.0-1.01.21.21.2-0.3-0.9-1.31.31.3-1.41.10.2-1.31.4
Short access day 1 total inactive lever presses4.48.812.0-2.7-3.53.13.02.83.3-3.1-3.13.03.03.1-2.7-3.2-3.02.92.8-2.62.82.5-2.93.0
Short access day 10 total inactive lever presses0.64.14.9-2.0-2.22.02.21.82.1-2.0-2.01.92.02.0-2.1-2.1-2.01.92.2-1.71.82.0-2.12.0
Short access day 1 total infusions2.85.48.2-2.4-1.82.22.52.92.0-2.3-2.32.52.42.4-1.5-2.3-2.62.62.5-2.62.21.2-2.42.7
Short access day 10 total infusions1.72.94.6-1.9-1.61.71.82.11.5-1.7-1.71.81.71.7-1.3-1.6-1.81.71.7-1.61.51.3-1.71.8
Short access total infusions1.31.83.5-1.5-0.81.21.61.91.0-1.3-1.31.51.41.4-0.5-1.2-1.61.41.5-1.51.20.5-1.61.6
Short access day 1 locomotion2.64.27.8-2.5-1.41.92.82.51.6-1.9-1.92.12.12.1-1.3-1.8-2.22.12.3-2.31.91.1-2.32.3
Short access day 10 total locomotion0.62.55.5-2.0-1.61.52.31.61.4-1.5-1.51.51.51.5-1.5-1.5-1.61.31.9-1.31.51.2-2.01.5
Short access total locomotion0.30.51.6-1.1-0.10.51.31.00.2-0.5-0.50.70.60.6-0.2-0.4-0.80.60.9-0.60.5-0.1-1.00.7
One hour access (0.3 mA shock)1.31.62.8-1.7-1.01.31.51.61.1-1.2-1.21.21.31.2-0.7-1.1-1.21.21.5-1.41.40.7-1.31.2
Compulsive drug intake1.11.63.21.70.8-1.1-1.7-1.8-0.81.11.1-1.5-1.2-1.20.61.01.4-1.2-1.51.4-1.4-0.21.4-1.3
One hour access (shock baseline)1.23.15.3-2.3-1.41.82.32.31.4-1.7-1.71.91.81.7-1.3-1.5-1.81.62.0-2.01.90.9-1.71.7
Social response proportion0.30.41.20.50.6-0.5-0.8-0.3-0.60.50.5-0.4-0.5-0.50.70.60.5-0.5-1.10.5-0.2-0.91.1-0.5
Social responses0.20.20.70.50.1-0.3-0.6-0.5-0.30.30.3-0.2-0.4-0.40.40.30.3-0.4-0.80.40.1-0.70.8-0.4
Social time0.20.42.00.40.7-0.6-0.4-0.4-0.70.60.6-0.4-0.5-0.61.10.60.5-0.4-0.40.3-0.5-1.40.5-0.5
Soleus weight4.413.016.5-3.3-4.03.83.33.43.8-3.7-3.63.63.63.6-3.9-3.6-3.43.63.5-3.43.74.1-3.53.2
Bone: stiffness0.00.00.0-0.2-0.10.10.2-0.10.2-0.1-0.10.10.10.1-0.2-0.10.00.10.1-0.20.20.1-0.1-0.0
Tibialis anterior weight3.512.014.2-3.1-3.73.53.33.13.6-3.5-3.53.63.43.5-3.7-3.6-3.43.53.3-3.33.73.8-3.33.2
Time to tail flick, vehicle, before self-admin0.70.81.80.31.2-1.0-0.2-0.4-1.31.01.0-0.9-0.9-0.91.21.10.7-0.8-0.40.7-1.2-1.30.5-0.6
Time to tail flick, vehicle, after self-admin2.14.25.71.82.4-2.2-1.9-1.8-2.42.22.2-1.8-2.1-2.12.12.21.9-1.8-1.82.0-2.2-2.21.8-2.0
Time to tail flick, test, before self-admin0.10.10.2-0.4-0.10.20.50.40.1-0.3-0.30.30.30.3-0.4-0.2-0.40.20.4-0.20.20.3-0.50.4
Time to tail flick, test, after self-admin0.20.20.6-0.8-0.50.40.30.60.2-0.4-0.30.30.40.3-0.4-0.2-0.40.40.6-0.30.30.2-0.50.3
Delta time to tail flick, vehicle, before/after SA0.10.10.70.70.4-0.3-0.8-0.4-0.20.30.3-0.1-0.3-0.30.20.20.2-0.1-0.40.4-0.2-0.20.4-0.3
Delta time to tail flick, test, before/after SA1.21.52.4-1.3-1.61.40.91.11.3-1.3-1.21.11.21.2-1.3-1.2-1.11.21.2-1.21.31.2-1.11.0
Tibia length2.87.910.22.92.8-2.7-2.9-2.7-2.72.72.7-2.7-2.8-2.82.82.72.8-2.8-3.22.7-2.7-2.93.2-2.7
Ambulatory time before self-admin0.00.00.1-0.2-0.10.20.30.00.1-0.1-0.00.10.0-0.0-0.10.00.1-0.10.1-0.00.00.2-0.0-0.2
Ambulatory time after self-admin1.11.72.21.41.5-1.2-1.4-1.5-1.01.31.2-1.4-1.3-1.41.41.21.5-1.4-1.31.2-1.4-1.21.3-1.4
Bone: tissue strength0.80.91.20.71.0-0.9-0.7-0.8-1.01.01.0-1.1-0.9-1.00.81.01.0-1.1-0.90.9-1.1-0.60.9-0.9
Total heroin consumption2.83.35.5-1.7-2.01.81.71.51.9-1.8-1.81.91.81.8-2.3-1.8-1.71.81.7-1.61.82.2-1.71.7
Bone: trabecular number2.54.77.3-1.4-2.72.51.31.92.6-2.4-2.42.32.22.2-2.7-2.4-2.22.31.3-2.02.32.5-1.22.0
Bone: trabecular spacing2.43.54.81.22.2-2.0-1.2-1.7-2.22.02.0-2.1-1.9-1.92.22.12.0-2.2-1.11.8-2.2-1.81.0-1.7
Bone: trabecular thickness0.50.71.20.0-1.11.0-0.00.61.1-0.9-1.01.00.90.9-1.1-1.0-0.91.1-0.0-0.71.00.80.00.7
Bone: trabecular tissue density0.30.50.8-0.9-0.50.70.90.60.8-0.7-0.70.50.70.7-0.6-0.7-0.60.50.8-0.80.70.5-0.80.6
Water consumed over 24 hours0.20.41.3-0.1-1.10.70.20.11.0-0.7-0.70.70.50.6-1.1-0.8-0.50.60.3-0.40.90.8-0.30.4
Number of responses in last shaping day0.30.30.8-0.50.40.50.50.90.3-0.5-0.50.80.60.50.4-0.4-0.70.70.3-0.90.9-0.3-0.30.7