Hub : Genes

Atp5mc1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Atp5mc1 0.32 0.11 0.0e+00 0.37 0.34 0.37 0.17 1.5e-43 1.9e-38 1.2e-43 3.5e-18
2 Liver alternative TSS NM_017311.1 0.04 0.03 7.4e-06 0.04 0.04 0.03 0.04 1.4e-05 7.3e-05 3.4e-04 2.3e-05
3 Liver alternative TSS XM_006247188.5 0.06 0.04 1.6e-08 0.07 0.07 0.07 0.08 5.6e-08 2.4e-08 1.0e-08 5.9e-09
4 Liver intron excision ratio chr10_81522788_81523301 0.2 0.1 4.4e-16 0.15 0.12 0.14 0.14 4.3e-16 1.3e-13 1.0e-15 7.9e-15
5 Liver intron excision ratio chr10_81522788_81523371 0.17 0.1 1.1e-16 0.15 0.13 0.14 0.13 3.2e-16 2.5e-14 8.6e-15 3.1e-14
6 NAcc gene expression Atp5mc1 0.02 0.02 9.9e-04 0.03 0.02 0.02 0.02 8.1e-05 1.3e-03 1.3e-04 1.4e-04
7 Liver isoform ratio XM_006247188.5 0.13 0.11 1.1e-10 0.08 0.07 0.09 0.08 5.3e-09 7.5e-08 2.9e-10 1.9e-09
8 Liver isoform ratio NM_017311.1 0.03 0.06 5.5e-03 0 0 -0 -0 8.4e-02 3.4e-01 7.5e-01 6.3e-01
9 RMTg isoform ratio XM_006247189.3 0.15 0.11 1.2e-03 0.03 0.06 0.08 0.04 5.9e-02 1.1e-02 4.5e-03 2.9e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density1.62.73.41.81.7-1.71.8-1.81.7-1.41.6-1.4
Area under the delay curve0.10.10.5-0.2-0.10.10.0-0.0-0.70.6-0.00.6
BMI with tail20.369.986.49.38.2-8.48.7-8.79.1-8.47.5-6.9
BMI without tail1.85.37.12.72.2-2.42.5-2.52.2-2.52.0-1.5
Body weight1.25.36.52.42.0-2.22.5-2.52.4-2.21.9-2.5
Weight adjusted by age0.10.20.5-0.6-0.20.3-0.40.4-0.7-0.3-0.20.6
Bone surface0.81.42.01.21.0-1.11.2-1.21.1-1.41.4-1.1
Bone volume1.52.73.21.81.5-1.61.7-1.71.7-1.61.7-1.7
Breakpoint value in progressive ratio session2.42.94.0-1.8-2.01.9-1.71.7-1.81.5-1.31.5
Number of licking bursts0.61.01.4-0.5-1.21.1-1.01.0-0.80.8-1.11.2
Context. condit. distance diff. score1.11.33.01.01.1-1.11.1-1.10.9-1.71.2-0.8
Locomotion velocity, session 10.00.00.1-0.0-0.10.1-0.20.20.2-0.4-0.30.1
Locomotion distance, session 14.45.56.7-2.4-2.62.5-2.42.4-2.41.8-2.32.3
Locomotion velocity, session 21.11.32.1-1.4-1.11.1-1.21.2-1.31.1-0.70.7
Locomotion distance, session 26.18.59.4-2.8-3.13.0-3.03.0-2.92.2-3.12.9
Locomotion velocity, session 30.40.41.60.30.5-0.50.5-0.50.3-0.31.2-0.9
Locomotion distance, session 31.41.52.2-1.4-1.11.1-1.21.2-1.51.1-0.91.3
Stereotopy head waving bouts, day 34.55.36.62.41.9-2.02.2-2.22.3-2.52.5-2.6
Stereotopy head waving duration, day 33.64.35.71.91.8-1.92.0-2.02.0-2.42.2-2.4
Locomotion velocity, session 71.11.21.6-1.1-1.31.2-1.11.1-1.10.5-1.21.1
Locomotion distance, session 75.67.18.8-2.7-2.92.8-2.72.7-2.81.5-3.02.6
Stereotopy head waving bouts, day 70.30.30.70.70.3-0.40.5-0.50.5-0.40.8-0.5
Stereotopy head waving duration, day 70.20.30.70.50.3-0.40.5-0.50.5-0.10.9-0.6
Locomotion velocity, session 80.91.13.60.90.8-0.80.7-0.70.7-1.91.4-0.7
Locomotion distance, session 80.60.81.6-1.0-0.90.9-0.80.8-1.30.1-0.71.1
Degree of sensitization distance0.20.20.8-0.3-0.60.5-0.40.4-0.1-0.3-0.90.3
Degree of sensitization stereotypy0.20.20.4-0.2-0.60.5-0.50.5-0.40.6-0.30.6
Conditioned locomotion1.61.83.01.31.7-1.61.4-1.41.2-1.40.8-1.0
Cocaine response after cond. corrected4.75.67.32.72.6-2.62.5-2.52.7-1.71.6-2.0
Cocaine response after cond. not corrected2.52.93.91.91.9-1.92.0-2.01.9-0.81.0-1.5
Cocaine response before conditioning2.93.44.9-2.0-2.01.9-1.71.7-2.02.2-1.71.5
Saline control response0.20.31.4-0.2-0.10.00.0-0.00.0-0.1-1.11.2
Bone: connectivity density0.40.71.00.80.8-0.91.0-1.00.7-0.81.0-0.5
Bone: cortical apparent density4.46.07.9-2.8-2.72.7-2.62.6-2.51.4-2.12.4
Bone: cortical area0.50.71.30.81.0-1.01.1-1.10.6-0.30.9-0.5
Bone: cortical porosity0.20.20.30.40.5-0.50.5-0.50.4-0.00.5-0.4
Bone: cortical porosity0.30.30.60.60.6-0.70.8-0.80.5-0.20.5-0.5
Bone: cortical thickness0.10.20.20.10.5-0.50.5-0.50.2-0.40.50.0
Bone: cortical thickness0.50.61.8-0.9-0.60.6-0.70.7-1.30.70.10.8
Bone: cortical tissue density5.06.88.9-3.0-2.92.8-2.82.8-2.61.5-2.32.5
Condit. Reinf. active minus inactive responses0.91.01.7-0.8-1.21.3-1.31.3-0.80.1-0.70.8
Condit. Reinf. active-inactive response ratio0.10.10.70.40.1-0.00.0-0.00.4-0.40.8-0.2
Condit. Reinf. active responses1.11.32.0-1.0-1.41.4-1.41.4-1.10.5-1.00.8
Condit. Reinf. inactive responses1.21.43.2-1.2-1.21.1-1.01.0-1.21.0-1.81.2
Incentive salience index mean1.82.23.0-1.3-1.61.7-1.71.7-1.41.0-1.21.3
Condit. Reinf. lever presses2.53.54.0-1.7-1.81.9-1.91.9-1.71.8-2.02.0
Condit. Reinf. active minus inactive responses0.20.20.9-0.1-0.20.2-0.20.2-0.10.7-1.00.7
Condit. Reinf. active-inactive response ratio0.30.41.60.2-0.20.2-0.30.30.00.7-1.31.0
Condit. Reinf. active responses0.10.10.4-0.1-0.20.10.0-0.0-0.20.3-0.60.6
Condit. Reinf. inactive responses0.00.00.1-0.3-0.0-0.00.2-0.2-0.3-0.30.3-0.0
Condit. Reinf. lever presses0.30.41.0-1.0-0.40.4-0.40.4-1.00.6-0.40.6
Condit. Reinf. lever reinforcers received0.10.10.6-0.3-0.30.2-0.10.1-0.30.3-0.60.8
Conditioned reinforcement - actives0.50.81.8-0.4-1.11.0-0.70.7-0.71.4-1.00.5
Conditioned reinforcement - inactives0.00.10.30.0-0.10.10.1-0.10.1-0.5-0.60.2
Conditioned locomotion0.20.30.50.60.5-0.60.7-0.70.70.50.0-0.4
Patch foraging indifference point 0 sec1.01.82.91.21.5-1.51.5-1.51.20.01.7-1.4
Patch foraging indifference point AUC0.10.10.2-0.40.10.1-0.40.4-0.2-0.4-0.00.1
Delay disc. indifference point, 0s delay0.20.20.8-0.60.00.0-0.10.1-0.70.4-0.70.9
Delay disc. indifference point, 16s delay1.01.11.91.01.2-1.21.2-1.20.6-0.31.4-0.8
Delay disc. indifference point, 2s delay0.10.10.2-0.2-0.00.1-0.10.1-0.40.5-0.40.4
Delay disc. indifference point, 24s delay0.40.51.0-0.6-0.70.7-0.60.6-0.61.0-0.60.9
Delay disc. indifference point, 4s delay1.51.63.1-1.4-1.21.1-1.01.0-1.81.2-0.91.4
Delay disc. indifference point, 8s delay0.10.20.6-0.3-0.30.2-0.10.1-0.70.8-0.20.4
Indifference point function ln k0.10.21.4-0.3-0.40.3-0.10.1-0.41.2-0.50.3
Indifference point function log k0.10.21.4-0.3-0.40.3-0.10.1-0.41.2-0.50.3
Patch foraging total patch changes 0 sec1.01.92.71.21.6-1.51.5-1.51.3-0.11.7-1.4
Patch foraging total patch changes 12 sec0.00.00.1-0.10.3-0.20.1-0.10.10.30.0-0.1
Patch foraging total patch changes 18 sec1.42.12.91.21.7-1.71.6-1.61.2-0.11.7-1.7
Patch foraging total patch changes 24 sec0.50.91.60.81.1-1.00.9-0.90.70.31.3-1.1
Patch foraging total patch changes 6 sec0.71.01.80.81.1-1.11.0-1.01.0-0.51.4-1.0
Patch foraging time to switch 0 sec0.00.10.1-0.1-0.20.2-0.30.3-0.3-0.2-0.20.1
Patch foraging water rate 0 sec1.22.63.71.51.6-1.61.6-1.61.5-1.21.9-1.6
Patch foraging water rate 12 sec0.30.61.60.50.5-0.70.9-0.90.4-0.61.3-0.5
Patch foraging water rate 18 sec0.00.00.2-0.1-0.20.10.0-0.0-0.10.4-0.20.3
Patch foraging water rate 24 sec1.11.61.91.31.2-1.21.3-1.31.1-1.41.4-1.2
Patch foraging water rate 6 sec0.10.10.20.30.0-0.10.2-0.2-0.30.40.40.2
Seeking ratio, delayed vs. immediate footshock3.44.211.21.62.0-2.01.9-1.91.8-3.31.8-1.6
Distance traveled before self-admin1.21.63.1-1.0-1.41.3-1.11.1-1.01.8-1.31.3
Distance traveled after self-admin0.10.20.60.60.0-0.10.2-0.20.10.70.8-0.1
Extensor digitorum longus weight0.93.54.91.72.0-2.01.9-1.91.7-1.72.2-1.6
Bone: elastic displacement0.00.00.10.30.2-0.20.2-0.20.2-0.20.3-0.2
Bone: elastic work0.00.00.10.00.1-0.20.3-0.3-0.1-0.10.10.0
Bone: endosteal estimation0.10.20.40.50.4-0.40.5-0.50.00.20.2-0.6
Bone: endosteal perimeter0.30.71.01.00.9-0.90.9-0.90.60.10.8-1.0
Epididymis fat weight0.10.40.70.70.4-0.60.7-0.70.8-0.5-0.2-0.2
Delta time in closed arm before/after self-admin0.50.52.10.50.4-0.50.5-0.50.8-1.50.3-0.4
Delta time in open arm before/after self-admin0.90.91.6-1.1-0.80.8-1.01.0-1.30.6-0.60.9
Diff in mean of infusions in LGA sessions1.11.32.7-0.8-1.61.5-1.31.3-0.80.7-1.10.9
Delay discount exponential model param0.20.20.70.30.3-0.30.1-0.10.8-0.60.1-0.7
Extinction: sum of active levers before priming1.01.11.7-1.1-1.11.0-0.90.9-1.10.9-1.31.0
Active lever presses in extinction session 60.20.20.70.40.3-0.30.3-0.30.20.60.9-0.4
Bone: final force0.20.30.60.70.6-0.60.7-0.70.5-0.10.1-0.0
Bone: final moment0.30.40.80.80.7-0.80.9-0.90.6-0.10.3-0.1
Food consumed during 24 hour testing period2.02.73.6-1.4-1.61.7-1.81.8-1.51.9-1.71.5
Glucose2.13.35.11.61.8-1.71.5-1.51.9-2.31.8-2.0
Heart weight1.32.03.21.71.0-1.21.4-1.41.6-1.81.0-1.3
Delay discount hyperbolic model param0.20.20.60.30.3-0.20.1-0.10.8-0.70.1-0.7
Intermittent access intake day 1-15 change0.20.43.10.0-0.10.1-0.20.2-0.61.80.1-0.1
Intermittent access intake escalation0.10.32.40.1-0.10.1-0.10.1-0.61.50.1-0.1
Intermittent access intake escalation 20.40.40.80.70.6-0.60.5-0.50.20.90.7-0.8
Intermitt. access day 1 inactive lever presses0.10.21.70.2-0.10.1-0.10.10.3-1.30.10.1
Intermitt. access day 15 inactive lever presses0.81.73.31.01.5-1.41.3-1.31.4-0.21.3-1.8
Intermitt. access escalation Index0.40.62.2-0.4-0.70.8-0.80.8-0.61.5-0.30.5
Intermittent access day 1 total infusions0.10.10.7-0.1-0.30.3-0.20.20.1-0.8-0.20.4
Intermittent access day 15 total infusions0.10.20.8-0.2-0.30.3-0.40.4-0.50.9-0.30.3
Intermittent access terminal intake (last 3 days)0.00.00.10.2-0.1-0.00.0-0.0-0.20.4-0.0-0.1
Intermittent access total infusions0.00.00.30.1-0.0-0.10.2-0.20.0-0.6-0.1-0.0
Intermittent access day 1 locomotion0.30.30.8-0.6-0.60.6-0.60.6-0.4-0.0-0.90.4
Intermittent access day 15 total locomotion0.20.41.6-0.2-0.60.5-0.30.3-0.51.3-0.90.4
Intermittent access total locomotion0.10.10.4-0.2-0.30.2-0.10.1-0.30.3-0.60.1
Intermittent access standard deviation0.40.81.20.91.0-1.11.1-1.10.60.40.7-1.0
Left kidney weight0.00.10.40.10.1-0.20.3-0.30.0-0.50.5-0.7
Right kidney weight0.41.82.41.21.2-1.21.3-1.31.4-1.41.4-1.6
Cocaine induced anxiety0.20.31.10.60.3-0.30.4-0.40.6-1.10.2-0.4
Post-drug Anxiety0.40.40.8-0.7-0.90.8-0.70.7-0.40.0-0.90.4
Baseline Anxiety1.51.73.1-1.5-1.41.3-1.21.2-1.21.8-1.10.9
Tail length19.375.294.5-9.6-8.78.8-8.88.8-9.78.7-7.66.9
Length with tail7.331.842.7-6.5-5.75.7-5.75.7-6.45.7-5.13.7
Length without tail0.20.71.90.60.6-0.70.9-0.90.7-1.00.4-1.4
Times rat made contact with spout0.91.02.0-0.7-1.01.0-1.11.1-0.31.3-1.40.6
Lifetime Intake0.00.00.10.00.1-0.10.1-0.1-0.0-0.30.1-0.0
Liver weight, left0.00.10.20.30.1-0.10.0-0.00.5-0.10.20.3
Liver weight, right0.10.10.2-0.3-0.50.4-0.30.3-0.40.30.20.0
Locomotor activity0.30.42.20.80.2-0.30.4-0.40.51.5-0.2-0.0
Locomotor testing distance0.61.02.01.40.8-1.01.2-1.21.21.00.3-0.3
Locomotor testing rearing0.10.20.40.60.4-0.50.6-0.60.30.70.10.3
Locomotion in novel chamber0.30.42.40.0-0.40.3-0.20.2-0.1-1.5-0.10.7
Locomotion in novel chamber post-restriction1.62.64.51.71.5-1.61.8-1.82.1-2.10.5-0.8
Fecal boli incidents, locomotor time 13.04.46.92.32.0-1.91.8-1.82.1-1.52.6-2.5
Change in fecal boli incidents, locomotor task1.91.92.9-1.4-1.71.6-1.31.3-1.40.1-1.41.5
Time >=10cm from walls, locomotor time 10.10.10.6-0.1-0.20.1-0.10.1-0.2-0.4-0.40.8
Bouts of movement, locomotor time 10.30.30.60.20.4-0.50.6-0.60.4-0.80.6-0.6
Total resting periods, locomotor time 10.70.81.50.60.7-0.80.9-0.90.8-1.20.9-1.0
Rest time, locomotor task time 10.10.20.50.20.4-0.40.2-0.20.70.40.1-0.7
Distance moved, locomotor task time 11.21.72.7-1.2-1.41.4-1.31.3-1.30.6-1.41.6
Vertical activity count, locomotor time 10.20.51.8-0.5-0.70.7-0.50.5-0.60.1-0.81.3
Time >=10cm from walls, locomotor time 20.30.51.0-0.6-0.70.7-0.80.8-0.4-0.0-0.81.0
Bouts of movement, locomotor time 20.00.10.30.30.2-0.20.2-0.20.1-0.60.0-0.1
Total resting periods, locomotor time 20.10.10.50.30.3-0.30.3-0.30.1-0.7-0.10.0
Rest time, locomotor task time 20.70.81.1-1.0-0.90.9-1.01.0-0.70.8-0.90.8
Distance moved, locomotor task time 20.10.10.2-0.3-0.40.3-0.20.2-0.5-0.2-0.10.2
Vertical activity count, locomotor time 20.00.00.1-0.0-0.20.1-0.00.0-0.2-0.3-0.20.3
Light reinforcement 10.00.10.20.40.2-0.30.4-0.40.30.00.00.1
Light reinforcement 20.20.30.5-0.5-0.30.5-0.70.7-0.60.7-0.70.6
Bone: marrow area0.10.10.20.40.3-0.30.4-0.4-0.10.30.1-0.5
Bone: maximum diameter0.40.81.11.10.9-1.01.0-1.00.7-0.00.9-0.8
Bone: maximum force0.61.11.81.11.1-1.21.3-1.31.0-0.61.0-0.8
Bone: maximum moment0.81.52.21.21.2-1.31.5-1.51.0-0.71.2-1.0
Mean time between licks in bursts0.51.22.10.81.2-1.31.4-1.41.1-0.90.4-0.7
Mean num. licks in bursts0.00.10.3-0.20.3-0.20.1-0.10.4-0.00.1-0.6
Cd content in liver0.10.10.50.3-0.00.00.0-0.00.20.1-0.50.7
Co content in liver0.10.10.60.2-0.10.0-0.00.0-0.0-0.8-0.10.2
Cu content in liver7.38.710.8-2.5-3.33.2-3.13.1-2.62.6-3.03.0
Fe content in liver0.60.71.1-0.8-0.90.8-0.80.8-0.90.6-1.01.1
K content in liver0.80.71.3-0.8-1.21.1-0.90.9-0.50.5-1.10.1
Mg content in liver4.95.06.8-2.2-2.62.5-2.32.3-2.01.5-2.61.9
Mn content in liver4.85.37.4-2.7-2.32.4-2.42.4-2.71.9-1.81.9
Na content in liver0.10.20.4-0.0-0.40.4-0.40.40.00.5-0.4-0.6
Rb content in liver0.60.71.9-0.3-1.31.0-0.60.6-0.80.2-0.81.4
Se content in liver0.20.20.60.60.6-0.50.4-0.40.8-0.40.1-0.2
Sr content in liver1.71.52.9-1.7-0.91.1-1.31.3-1.51.4-0.70.5
Zn content in liver0.10.10.30.2-0.50.4-0.30.30.20.1-0.50.4
Bone: minimum diameter0.10.10.30.10.2-0.30.6-0.60.00.30.1-0.5
Time in familiar zone, hab. session 10.20.20.9-0.2-0.20.2-0.20.2-0.3-0.3-0.70.9
Time in novel zone, hab. session 12.32.34.71.61.2-1.31.4-1.41.3-1.02.0-2.2
Total zone transitions, hab. session 16.59.111.1-3.0-3.23.2-3.13.1-2.92.0-3.23.3
Total locomotion distance, hab. session 13.65.16.3-2.1-2.52.4-2.22.2-2.31.4-2.42.5
Locomotion velocity, hab. session 14.76.68.6-2.5-2.82.7-2.52.5-2.51.7-2.92.9
Time in familiar zone, hab. session 21.31.31.71.21.2-1.21.1-1.11.2-1.31.3-0.9
Time in novel zone, hab. session 20.20.20.3-0.4-0.40.4-0.30.3-0.50.4-0.50.4
Total zone transitions, hab. session 24.35.56.5-2.3-2.42.4-2.32.3-2.22.0-2.52.4
Total locomotion distance, hab. session 20.91.12.0-0.9-1.21.2-1.01.0-0.90.8-1.41.0
Locomotion velocity, hab. session 21.11.42.1-1.1-1.41.3-1.21.2-1.10.9-1.51.0
Novel to familiar place preference ratio0.20.20.8-0.3-0.40.4-0.30.3-0.60.3-0.30.9
Novelty place preference0.20.20.7-0.3-0.30.3-0.30.3-0.60.2-0.10.9
Time in novel zone, NPP test0.10.10.6-0.1-0.20.2-0.10.1-0.40.00.10.7
Total zone transitions, NPP test6.49.211.8-3.1-2.82.9-2.92.9-3.03.0-3.43.3
Total locomotion distance, NPP test2.02.84.4-1.6-1.61.5-1.51.5-1.71.5-2.11.9
Locomotion velocity, NPP test2.63.75.4-2.0-1.81.8-1.81.8-1.91.8-2.32.0
Intraocular pressure1.21.73.4-1.6-1.21.1-0.90.9-1.41.8-1.31.2
Delta distance traveled before/after self-admin1.41.52.61.31.3-1.31.2-1.20.9-1.11.6-1.0
Delta ambulatory time before/after self-admin1.41.82.61.51.2-1.21.2-1.21.4-1.61.5-1.1
Parametrial fat weight0.10.31.10.50.3-0.50.6-0.60.5-1.10.3-0.3
Pavlov. Cond. lever latency1.51.83.51.11.2-1.21.3-1.31.2-1.41.5-1.9
Pavlov. Cond. magazine entry latency0.10.20.3-0.3-0.30.4-0.40.4-0.40.4-0.30.6
Pavlov. Cond. change in total contacts3.53.74.9-1.8-2.02.0-1.91.9-1.81.7-2.02.2
Pavlov. Cond. index score0.91.22.3-0.9-1.01.0-1.01.0-0.91.0-1.11.5
Pavlov. Cond. latency score0.91.22.2-0.9-1.01.1-1.11.1-0.91.0-1.11.5
Pavlov. Cond. lever contacts2.93.55.2-1.7-1.71.8-1.81.8-1.71.9-2.12.3
Pavlov. Cond. magazine entry number0.60.81.40.70.8-0.80.8-0.80.8-0.90.9-1.2
Pavlov. Cond. intertrial magazine entries0.91.12.4-1.0-1.31.2-1.01.0-0.80.1-1.60.9
Pavlov. Cond. lever-magazine prob. diff.0.91.22.3-0.9-1.01.0-1.01.0-1.01.1-1.11.5
Pavlov. Cond. response bias1.11.32.6-0.9-1.01.0-1.01.0-1.11.2-1.31.6
Pavlov. Cond. lever latency1.62.23.1-1.0-1.81.6-1.41.4-0.91.7-1.71.6
Pavlov. Cond. magazine entry latency0.20.30.7-0.8-0.30.5-0.70.7-0.50.3-0.4-0.1
Pavlov. Cond. change in total contacts0.40.61.20.31.1-1.00.7-0.70.2-0.50.9-1.0
Pavlov. Cond. index score0.40.61.30.30.9-0.80.6-0.60.4-0.80.8-1.1
Pavlov. Cond. latency score0.20.20.80.00.6-0.50.3-0.30.1-0.30.4-0.9
Pavlov. Cond. lever contacts1.31.82.81.01.7-1.51.3-1.30.9-1.51.5-1.4
Pavlov. Cond. magazine entry number0.20.20.90.2-0.30.2-0.10.1-0.10.8-0.50.9
Pavlov. Cond. intertrial magazine entries1.52.34.2-1.2-1.81.6-1.31.3-1.51.4-1.62.0
Pavlov. Cond. lever-magazine prob. diff.0.50.71.40.31.0-0.90.7-0.70.4-0.90.9-1.2
Pavlov. Cond. response bias1.31.82.41.01.6-1.41.2-1.21.0-1.61.4-1.5
Time in closed arm before self-admin3.03.84.71.92.0-1.91.9-1.91.7-2.02.1-2.2
Time in closed arm after self-admin4.14.48.42.12.0-1.91.8-1.82.1-2.91.9-2.2
Time in open arm before self-admin0.50.51.8-0.4-0.60.6-0.40.4-0.30.2-1.21.3
Time in open arm after self-admin2.42.74.3-1.7-1.51.5-1.51.5-1.81.5-1.62.1
Bone: periosteal estimation0.40.71.30.90.9-1.01.1-1.10.6-0.10.6-0.7
Bone: periosteal perimeter1.32.22.91.61.7-1.71.7-1.71.2-0.61.5-1.3
Bone: post-yield work1.01.42.31.01.0-1.11.3-1.30.9-1.51.5-1.2
Progressive ratio test 1 active lever presses1.11.31.6-1.1-1.21.2-1.21.2-1.01.0-1.21.2
Progressive ratio test 1 breakpoint0.81.01.3-0.9-1.11.0-1.11.1-0.80.8-1.01.1
Progressive ratio test 1 inactive lever presses0.30.40.70.60.7-0.60.4-0.40.9-0.80.6-0.3
Progressive ratio test 2 active lever presses0.50.61.1-0.4-0.90.7-0.50.5-0.61.1-1.10.9
Progressive ratio test 2 breakpoint0.50.51.0-0.3-0.90.7-0.50.5-0.61.0-1.00.9
Progressive ratio test 2 inactive lever presses0.10.10.60.30.1-0.20.3-0.30.3-0.8-0.1-0.1
Incentive Sensitization - Responses0.10.10.40.2-0.2-0.10.3-0.3-0.10.7-0.60.4
Incentive Sensitization - Breakpoint0.10.10.40.4-0.0-0.20.5-0.5-0.10.6-0.40.2
Sum of active levers in priming session hrs 5-64.44.14.8-2.2-2.22.1-2.12.1-2.12.0-1.61.9
Progressive ratio0.10.20.40.30.6-0.50.4-0.40.3-0.5-0.20.2
Food seeking constrained by brief footshock0.40.54.40.1-0.10.1-0.10.1-0.22.10.1-0.4
Seeking ratio, punishment vs. effort0.71.02.4-0.9-1.11.1-1.01.0-1.01.5-0.40.3
Retroperitoneal fat weight0.41.62.31.21.4-1.51.5-1.51.2-1.30.6-1.0
Reaction time number correct0.61.21.80.61.2-1.31.3-1.30.7-0.71.3-0.9
Reaction time mean minus median1.02.43.4-1.8-1.51.5-1.61.6-1.51.7-1.51.0
Reaction time mean minus median AUC1.33.24.0-1.9-1.81.8-1.81.8-1.61.9-2.01.3
Reaction time num false alarms1.11.63.8-1.0-1.41.3-1.21.2-1.02.0-1.01.0
Reaction time num false alarms AUC1.21.94.4-1.2-1.61.5-1.31.3-1.22.1-1.11.1
Reaction time trials correct on left0.61.21.80.61.2-1.31.3-1.30.7-0.71.3-0.9
Reaction time trials on left0.61.11.70.61.2-1.31.3-1.30.7-0.61.2-0.8
Reaction time mean0.61.01.5-1.0-1.11.2-1.21.2-0.70.5-1.20.5
Reaction time mean AUC0.71.21.8-1.1-1.21.3-1.31.3-0.70.6-1.30.6
Median of all reaction times0.30.40.8-0.5-0.80.8-0.90.9-0.30.0-0.80.2
Reaction time omissions1.42.13.2-1.6-1.41.4-1.41.4-1.41.8-1.41.0
Reaction time false alarm rate1.82.54.5-1.2-1.81.7-1.61.6-1.32.1-1.51.2
Reaction time premature initiation rate0.30.50.8-0.9-0.40.5-0.60.6-0.70.9-0.80.7
Reaction time premature initiations0.10.20.5-0.70.2-0.1-0.00.0-0.50.7-0.10.3
Std. dev. reaction times1.22.12.7-1.6-1.51.5-1.61.6-1.21.6-1.50.8
Reaction time trials completed0.61.11.70.61.2-1.31.3-1.30.7-0.61.2-0.8
Reaction time trials AUC0.61.11.70.61.2-1.31.3-1.30.7-0.61.3-0.8
Run reversals in cocaine runway, females0.10.10.6-0.3-0.30.3-0.30.3-0.50.70.3-0.0
Run reversals in cocaine runway, males1.51.52.71.41.3-1.31.3-1.31.5-1.60.0-0.1
Latency to leave start box in cocaine runway6.97.814.32.72.7-2.62.5-2.52.5-3.82.7-2.9
Latency to leave start box in cocaine runway, F8.69.813.73.03.3-3.23.0-3.02.8-3.73.0-3.1
Latency to leave start box in cocaine runway, M0.70.62.60.80.3-0.30.4-0.40.7-1.60.7-0.9
Std. dev. time between licks in bursts0.70.91.50.71.2-1.21.1-1.10.8-0.00.6-1.0
Total sessions with >9 infusions0.00.00.2-0.00.2-0.1-0.10.10.00.40.1-0.2
Short access day 1 total inactive lever presses0.40.51.8-1.3-0.50.4-0.30.3-1.10.3-0.40.9
Short access day 10 total inactive lever presses0.61.62.11.11.2-1.31.4-1.41.2-1.41.0-1.0
Short access day 1 total infusions0.20.21.2-0.30.4-0.30.2-0.2-0.31.10.4-0.5
Short access day 10 total infusions0.00.00.20.20.1-0.10.1-0.10.2-0.20.0-0.5
Short access total infusions0.10.20.40.20.6-0.50.4-0.40.2-0.20.5-0.6
Short access day 1 locomotion0.40.51.30.70.8-0.70.6-0.60.80.20.7-1.1
Short access day 10 total locomotion0.10.21.60.30.1-0.10.2-0.20.41.3-0.2-0.6
Short access total locomotion0.20.30.70.50.5-0.50.4-0.40.60.50.2-0.8
One hour access (0.3 mA shock)0.50.61.1-0.7-0.80.8-0.80.8-0.90.2-0.61.0
Compulsive drug intake2.42.93.8-1.7-2.01.9-1.91.9-1.70.4-1.01.9
One hour access (shock baseline)0.60.81.21.11.0-1.01.0-1.00.9-0.70.6-0.9
Social response proportion2.22.53.9-1.6-1.71.8-2.02.0-1.51.3-1.01.2
Social responses0.00.10.2-0.0-0.10.2-0.30.3-0.1-0.00.40.3
Social time0.10.20.60.50.4-0.30.2-0.20.8-0.1-0.20.5
Soleus weight1.75.16.42.32.1-2.22.2-2.22.0-2.32.5-2.4
Bone: stiffness0.10.10.30.40.2-0.30.5-0.50.3-0.20.2-0.2
Tibialis anterior weight0.10.31.1-0.5-0.40.4-0.50.5-0.61.0-0.10.8
Time to tail flick, vehicle, before self-admin2.72.84.1-1.7-1.81.8-1.81.8-1.60.3-1.62.0
Time to tail flick, vehicle, after self-admin1.21.62.41.11.4-1.41.4-1.40.9-1.51.0-1.1
Time to tail flick, test, before self-admin0.50.51.10.50.7-0.60.5-0.50.4-0.80.9-1.0
Time to tail flick, test, after self-admin1.11.22.90.81.0-1.01.0-1.00.9-1.71.1-1.1
Delta time to tail flick, vehicle, before/after SA5.45.26.42.22.5-2.52.4-2.42.0-1.82.3-2.3
Delta time to tail flick, test, before/after SA0.20.20.5-0.5-0.50.4-0.30.3-0.50.4-0.40.7
Tibia length0.82.12.81.41.5-1.61.7-1.71.2-1.41.3-1.3
Ambulatory time before self-admin0.60.91.9-0.7-1.00.9-0.70.7-0.71.4-1.11.0
Ambulatory time after self-admin0.10.10.40.60.0-0.10.3-0.30.30.50.6-0.2
Bone: tissue strength1.21.21.70.71.1-1.21.3-1.31.0-1.20.8-0.9
Total heroin consumption1.11.21.7-1.1-1.31.3-1.11.1-1.20.8-0.61.2
Bone: trabecular number0.30.61.01.00.6-0.60.7-0.70.9-0.90.6-0.5
Bone: trabecular spacing0.10.10.60.00.1-0.0-0.20.2-0.10.8-0.40.6
Bone: trabecular thickness4.25.27.11.92.4-2.42.4-2.42.0-1.72.6-2.7
Bone: trabecular tissue density0.30.42.8-0.6-0.10.1-0.10.1-0.31.7-0.9-0.1
Water consumed over 24 hours0.10.10.2-0.1-0.20.3-0.40.4-0.10.4-0.20.4
Number of responses in last shaping day1.31.42.81.01.2-1.21.2-1.21.2-1.70.9-0.8