Hub : Genes

Atp5f1d

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain mRNA stability Atp5f1d 0.04 0.03 8.1e-04 0.03 0.02 0.01 0.02 1.0e-03 2.6e-03 3.6e-02 3.0e-03
2 PL alternative TSS XM_063262989.1 0.03 0.02 2.0e-04 0.03 0.03 0.03 0.03 7.8e-04 2.2e-04 3.8e-04 4.0e-04
3 OFC alternative TSS XM_063262989.1 0.1 0.08 5.2e-03 0.07 0.07 0.01 0.07 1.2e-02 7.7e-03 1.9e-01 1.0e-02
4 OFC alternative TSS XM_063262988.1 0.17 0.12 1.3e-03 0.14 0.12 0.06 0.13 3.5e-04 9.7e-04 1.2e-02 5.9e-04
5 Brain alternative TSS XM_063262989.1 0.05 0.04 1.7e-05 0.05 0.04 0.04 0.05 9.3e-06 8.3e-05 5.7e-05 2.8e-05
6 NAcc intron excision ratio chr7_10214758_10216460 0.01 0.01 8.5e-03 0.01 0 0 0 1.3e-02 8.5e-02 8.0e-02 1.1e-01
7 Brain alternative TSS XM_063262988.1 0.06 0.04 7.7e-06 0.06 0.05 0.05 0.05 2.9e-06 1.3e-05 2.0e-05 8.7e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density0.20.40.8-0.7-0.1-0.30.90.70.9-0.7
Area under the delay curve1.62.42.71.6-1.6-1.6-1.31.61.5-1.6
BMI with tail6.622.926.24.8-4.9-4.9-5.14.64.6-4.6
BMI without tail1.26.37.92.7-2.6-2.5-2.82.42.2-2.2
Body weight1.04.24.82.1-2.1-2.1-2.22.12.0-1.9
Weight adjusted by age0.20.61.41.2-0.8-0.7-0.80.50.6-0.4
Bone surface0.61.13.9-1.80.60.32.00.20.3-0.3
Bone volume0.51.03.9-1.60.40.22.00.40.6-0.3
Breakpoint value in progressive ratio session2.44.44.9-1.92.22.21.7-2.2-2.22.2
Number of licking bursts0.10.20.80.9-0.3-0.2-0.6-0.1-0.00.2
Context. condit. distance diff. score0.30.30.50.5-0.5-0.5-0.60.70.2-0.7
Locomotion velocity, session 10.60.61.5-1.20.80.71.2-0.3-0.40.4
Locomotion distance, session 10.50.62.6-1.60.70.51.00.1-0.1-0.1
Locomotion velocity, session 24.55.410.3-3.22.52.32.6-1.7-2.01.6
Locomotion distance, session 21.92.76.3-2.51.71.52.1-1.1-0.91.0
Locomotion velocity, session 36.47.48.5-2.52.82.92.4-2.8-2.92.7
Locomotion distance, session 30.00.00.10.3-0.00.0-0.1-0.1-0.1-0.0
Stereotopy head waving bouts, day 35.56.68.0-2.82.72.62.5-2.5-2.52.3
Stereotopy head waving duration, day 36.68.18.8-3.03.02.92.8-2.9-2.82.7
Locomotion velocity, session 70.50.50.9-0.60.70.71.0-0.6-0.90.7
Locomotion distance, session 70.30.30.91.0-0.6-0.5-0.80.30.2-0.2
Stereotopy head waving bouts, day 70.10.10.3-0.50.10.00.50.10.2-0.3
Stereotopy head waving duration, day 70.40.51.4-1.10.70.61.2-0.4-0.20.2
Locomotion velocity, session 80.81.02.6-1.61.00.81.5-0.3-0.50.4
Locomotion distance, session 80.30.41.1-1.00.70.60.7-0.1-0.50.2
Degree of sensitization distance0.40.50.80.6-0.7-0.7-0.60.90.5-0.6
Degree of sensitization stereotypy1.61.82.51.0-1.3-1.4-0.91.51.6-1.5
Conditioned locomotion1.51.83.41.8-1.4-1.2-1.70.91.0-0.9
Cocaine response after cond. corrected4.46.69.73.1-2.8-2.6-3.02.22.0-2.1
Cocaine response after cond. not corrected4.76.810.53.2-2.8-2.6-3.12.22.0-2.1
Cocaine response before conditioning0.50.60.9-0.70.80.81.0-0.7-0.80.7
Saline control response0.20.20.50.6-0.5-0.4-0.70.30.3-0.2
Bone: connectivity density0.30.51.0-0.3-0.5-0.60.20.91.0-0.9
Bone: cortical apparent density0.81.21.71.0-1.2-1.2-0.91.01.3-1.1
Bone: cortical area0.40.71.10.4-0.8-0.90.11.11.1-1.0
Bone: cortical porosity0.20.20.6-0.60.40.30.8-0.0-0.00.2
Bone: cortical porosity0.20.20.5-0.60.1-0.00.70.40.4-0.2
Bone: cortical thickness1.01.72.61.0-1.3-1.4-0.71.51.6-1.4
Bone: cortical thickness0.10.10.50.7-0.10.0-0.2-0.4-0.20.4
Bone: cortical tissue density0.50.81.20.8-1.0-1.0-0.70.81.1-0.9
Condit. Reinf. active minus inactive responses4.85.46.3-2.42.42.42.1-2.4-2.52.1
Condit. Reinf. active-inactive response ratio2.22.43.4-1.21.61.61.1-1.7-1.81.6
Condit. Reinf. active responses4.25.47.6-2.82.42.32.4-2.1-2.21.9
Condit. Reinf. inactive responses1.01.33.0-1.71.21.01.5-0.4-0.70.7
Incentive salience index mean2.63.45.2-2.32.01.91.8-1.6-1.81.4
Condit. Reinf. lever presses0.20.31.5-1.20.40.20.80.20.2-0.2
Condit. Reinf. active minus inactive responses1.52.43.9-0.61.51.61.3-1.9-1.52.0
Condit. Reinf. active-inactive response ratio0.10.20.60.80.00.1-0.4-0.5-0.00.7
Condit. Reinf. active responses1.82.63.7-0.81.61.61.7-1.9-1.41.9
Condit. Reinf. inactive responses0.91.42.2-0.91.21.21.5-1.2-1.21.1
Condit. Reinf. lever presses1.62.33.1-1.01.51.61.3-1.7-1.61.8
Condit. Reinf. lever reinforcers received1.31.83.0-0.41.31.41.3-1.7-1.21.7
Conditioned reinforcement - actives0.31.21.8-0.61.11.20.8-1.3-1.41.1
Conditioned reinforcement - inactives0.00.10.20.3-0.2-0.1-0.5-0.1-0.0-0.2
Conditioned locomotion6.29.29.8-3.13.13.13.0-3.0-2.92.9
Patch foraging indifference point 0 sec0.10.30.70.2-0.5-0.6-0.20.70.8-0.5
Patch foraging indifference point AUC0.41.01.4-0.71.01.00.8-1.1-1.11.2
Delay disc. indifference point, 0s delay7.38.311.02.0-2.8-3.0-2.13.33.3-3.3
Delay disc. indifference point, 16s delay0.10.10.20.4-0.4-0.4-0.20.30.5-0.4
Delay disc. indifference point, 2s delay6.16.88.22.1-2.7-2.7-2.22.82.8-2.9
Delay disc. indifference point, 24s delay0.50.81.31.2-1.0-0.9-0.70.80.9-0.6
Delay disc. indifference point, 4s delay1.11.21.80.9-1.1-1.1-0.71.11.1-1.3
Delay disc. indifference point, 8s delay0.91.62.61.6-1.4-1.3-1.21.21.0-1.0
Indifference point function ln k0.10.20.30.6-0.5-0.5-0.30.30.4-0.4
Indifference point function log k0.10.20.30.6-0.5-0.5-0.30.30.4-0.4
Patch foraging total patch changes 0 sec0.10.20.40.2-0.5-0.5-0.20.60.7-0.5
Patch foraging total patch changes 12 sec0.40.61.30.7-0.8-0.7-1.10.70.6-0.4
Patch foraging total patch changes 18 sec0.51.21.6-1.31.11.11.1-0.9-1.01.1
Patch foraging total patch changes 24 sec0.00.10.2-0.50.30.20.3-0.1-0.10.3
Patch foraging total patch changes 6 sec0.10.20.5-0.60.50.50.7-0.3-0.20.5
Patch foraging time to switch 0 sec0.41.52.90.1-1.0-1.2-0.71.71.4-1.7
Patch foraging water rate 0 sec0.10.31.21.1-0.3-0.1-0.6-0.4-0.30.4
Patch foraging water rate 12 sec0.52.15.02.2-1.5-1.3-1.80.80.9-0.8
Patch foraging water rate 18 sec0.30.71.81.3-0.10.2-1.0-0.9-0.80.8
Patch foraging water rate 24 sec0.91.23.92.0-1.0-0.7-1.80.10.1-0.1
Patch foraging water rate 6 sec0.30.51.10.60.30.5-0.2-1.0-0.91.0
Seeking ratio, delayed vs. immediate footshock3.44.95.5-2.42.32.22.3-2.1-2.02.1
Distance traveled before self-admin0.10.20.50.3-0.5-0.5-0.10.60.5-0.7
Distance traveled after self-admin0.00.00.0-0.10.10.00.20.0-0.00.1
Extensor digitorum longus weight4.417.421.24.6-4.4-4.2-4.63.93.5-3.9
Bone: elastic displacement0.10.20.3-0.30.30.30.5-0.5-0.30.4
Bone: elastic work0.30.40.60.7-0.7-0.7-0.10.80.6-0.7
Bone: endosteal estimation0.10.30.60.5-0.5-0.6-0.30.70.4-0.8
Bone: endosteal perimeter0.30.71.4-1.00.80.81.2-0.6-0.70.5
Epididymis fat weight0.00.20.80.5-0.00.1-0.9-0.3-0.40.2
Delta time in closed arm before/after self-admin1.11.13.11.8-1.0-0.8-1.60.30.3-0.3
Delta time in open arm before/after self-admin0.40.50.60.7-0.7-0.7-0.70.70.7-0.6
Diff in mean of infusions in LGA sessions1.22.22.4-1.51.61.61.3-1.5-1.51.5
Delay discount exponential model param1.52.02.3-1.51.51.51.2-1.4-1.41.4
Extinction: sum of active levers before priming0.60.91.3-0.70.91.00.4-1.0-1.11.1
Active lever presses in extinction session 62.22.22.8-1.61.51.51.7-1.3-1.31.5
Bone: final force1.32.13.21.2-1.5-1.6-0.61.81.6-1.6
Bone: final moment1.11.72.61.1-1.3-1.4-0.51.61.4-1.5
Food consumed during 24 hour testing period0.40.81.21.1-1.0-0.9-0.80.80.7-0.8
Glucose3.04.85.62.4-2.3-2.2-2.02.12.3-1.9
Heart weight0.50.91.5-0.30.80.90.2-1.2-1.21.1
Delay discount hyperbolic model param2.73.53.9-1.92.02.01.5-1.9-1.91.9
Intermittent access intake day 1-15 change1.16.37.9-2.02.52.62.1-2.7-2.72.8
Intermittent access intake escalation1.05.56.9-1.92.42.42.0-2.5-2.52.6
Intermittent access intake escalation 23.05.06.3-1.92.32.32.0-2.4-2.32.5
Intermitt. access day 1 inactive lever presses0.00.20.40.40.10.2-0.4-0.5-0.60.5
Intermitt. access day 15 inactive lever presses0.10.50.7-0.80.70.70.7-0.7-0.70.5
Intermitt. access escalation Index0.30.91.40.5-0.9-1.0-0.31.21.2-1.2
Intermittent access day 1 total infusions0.00.10.40.00.30.4-0.0-0.5-0.60.3
Intermittent access day 15 total infusions1.43.44.2-1.51.91.91.6-2.0-2.01.9
Intermittent access terminal intake (last 3 days)1.32.22.5-1.31.51.61.3-1.6-1.61.5
Intermittent access total infusions0.91.01.4-0.81.01.10.8-1.1-1.21.0
Intermittent access day 1 locomotion0.91.72.8-0.81.31.40.7-1.6-1.71.4
Intermittent access day 15 total locomotion1.35.16.5-1.92.32.41.7-2.6-2.52.4
Intermittent access total locomotion2.22.63.5-1.31.61.71.2-1.8-1.91.6
Intermittent access standard deviation1.47.37.8-2.52.82.82.7-2.7-2.82.7
Left kidney weight0.00.10.50.7-0.2-0.1-0.6-0.1-0.40.1
Right kidney weight0.31.93.5-0.61.21.40.8-1.6-1.91.7
Cocaine induced anxiety0.61.83.6-1.91.41.31.7-0.9-0.90.9
Post-drug Anxiety1.51.73.8-1.91.41.31.5-0.9-0.90.9
Baseline Anxiety0.00.10.1-0.10.20.30.2-0.3-0.30.3
Tail length2.513.215.3-3.23.73.73.5-3.6-3.93.7
Length with tail1.98.510.0-2.63.03.02.7-2.9-3.23.0
Length without tail0.00.00.10.3-0.1-0.1-0.20.10.1-0.1
Times rat made contact with spout0.30.30.80.9-0.6-0.5-0.70.30.3-0.2
Lifetime Intake0.40.50.8-0.50.70.80.5-0.8-0.90.7
Liver weight, left0.91.62.11.4-1.3-1.3-1.41.11.2-1.1
Liver weight, right0.61.11.71.3-1.1-1.1-1.20.90.7-1.0
Locomotor activity3.25.08.1-2.82.22.12.8-1.8-1.72.0
Locomotor testing distance1.33.25.2-2.31.81.72.3-1.4-1.31.6
Locomotor testing rearing0.00.10.20.30.00.10.1-0.3-0.10.4
Locomotion in novel chamber0.71.01.5-0.71.01.00.8-1.1-1.01.2
Locomotion in novel chamber post-restriction0.61.82.3-1.11.31.41.3-1.4-1.51.4
Fecal boli incidents, locomotor time 10.82.02.91.4-1.4-1.4-1.71.51.2-1.3
Change in fecal boli incidents, locomotor task0.20.31.1-0.40.40.31.1-0.3-0.20.4
Time >=10cm from walls, locomotor time 10.50.61.20.3-0.7-0.80.01.11.1-0.6
Bouts of movement, locomotor time 10.30.40.7-0.40.60.60.5-0.6-0.80.7
Total resting periods, locomotor time 10.50.50.8-0.60.70.70.7-0.7-0.90.7
Rest time, locomotor task time 10.30.40.7-0.80.70.60.6-0.5-0.80.4
Distance moved, locomotor task time 10.30.91.90.5-0.9-1.0-0.11.21.4-1.0
Vertical activity count, locomotor time 10.10.51.21.1-0.8-0.7-0.40.50.9-0.3
Time >=10cm from walls, locomotor time 20.61.82.81.7-1.5-1.4-1.31.41.2-0.9
Bouts of movement, locomotor time 20.20.51.4-1.20.80.70.8-0.5-0.50.3
Total resting periods, locomotor time 20.10.51.4-1.20.70.60.9-0.4-0.40.3
Rest time, locomotor task time 20.50.91.5-1.21.00.91.2-0.7-0.80.7
Distance moved, locomotor task time 20.60.81.31.0-0.9-0.9-1.10.80.7-0.7
Vertical activity count, locomotor time 20.40.81.71.3-0.9-0.8-1.30.60.5-0.5
Light reinforcement 12.511.315.1-3.93.53.43.4-3.1-3.13.1
Light reinforcement 21.33.04.1-2.01.81.81.8-1.6-1.41.5
Bone: marrow area0.10.30.60.5-0.5-0.5-0.30.70.4-0.8
Bone: maximum diameter0.91.83.4-1.61.41.31.9-1.0-1.01.0
Bone: maximum force1.12.23.01.4-1.5-1.6-0.81.71.5-1.6
Bone: maximum moment1.01.82.51.3-1.4-1.5-0.71.61.4-1.5
Mean time between licks in bursts1.06.06.7-2.22.52.62.3-2.6-2.32.6
Mean num. licks in bursts0.00.00.1-0.1-0.1-0.20.00.20.1-0.3
Cd content in liver0.10.20.3-0.30.40.40.5-0.4-0.10.4
Co content in liver1.51.72.3-0.91.31.41.2-1.5-1.21.5
Cu content in liver0.30.30.9-0.80.50.40.9-0.2-0.10.2
Fe content in liver0.10.20.3-0.20.50.50.1-0.5-0.60.5
K content in liver0.10.10.4-0.60.20.10.50.10.2-0.1
Mg content in liver0.30.30.5-0.70.60.50.7-0.5-0.30.4
Mn content in liver1.82.14.7-2.01.41.32.2-0.8-0.90.8
Na content in liver0.70.81.40.2-0.8-0.9-0.51.21.1-1.2
Rb content in liver0.20.20.6-0.70.20.10.80.20.3-0.2
Se content in liver0.30.30.4-0.60.60.60.4-0.5-0.60.5
Sr content in liver0.00.00.10.3-0.1-0.1-0.3-0.0-0.00.0
Zn content in liver3.33.95.9-1.21.92.11.1-2.4-2.22.4
Bone: minimum diameter0.00.10.2-0.1-0.1-0.10.40.30.1-0.3
Time in familiar zone, hab. session 12.12.43.4-1.21.51.61.2-1.7-1.81.6
Time in novel zone, hab. session 11.11.22.10.7-1.1-1.1-0.51.31.4-1.3
Total zone transitions, hab. session 11.11.53.4-1.81.31.11.6-0.8-0.70.7
Total locomotion distance, hab. session 11.52.25.0-2.21.51.32.1-0.8-0.90.8
Locomotion velocity, hab. session 12.02.96.1-2.51.81.62.1-1.2-1.21.1
Time in familiar zone, hab. session 26.06.88.7-2.22.72.82.0-2.8-2.92.8
Time in novel zone, hab. session 24.65.06.51.9-2.3-2.4-1.62.42.6-2.4
Total zone transitions, hab. session 20.40.50.8-0.9-0.1-0.30.30.70.9-0.9
Total locomotion distance, hab. session 21.41.94.6-2.11.41.31.5-1.0-0.90.9
Locomotion velocity, hab. session 21.51.95.2-2.31.41.21.6-0.9-0.80.7
Novel to familiar place preference ratio3.54.66.31.6-2.1-2.3-1.42.52.5-2.4
Novelty place preference2.12.74.01.1-1.6-1.7-1.02.01.9-1.9
Time in novel zone, NPP test2.63.14.41.2-1.8-1.9-1.22.12.0-2.0
Total zone transitions, NPP test0.10.20.9-0.90.20.00.30.20.5-0.3
Total locomotion distance, NPP test0.10.20.8-0.90.20.00.40.30.3-0.4
Locomotion velocity, NPP test0.20.31.4-1.20.50.30.7-0.00.1-0.1
Intraocular pressure0.20.30.80.8-0.2-0.0-0.9-0.3-0.40.4
Delta distance traveled before/after self-admin0.40.50.8-0.60.70.70.5-0.7-0.70.9
Delta ambulatory time before/after self-admin0.30.50.5-0.70.70.70.6-0.6-0.70.7
Parametrial fat weight0.00.00.1-0.30.0-0.00.10.2-0.0-0.2
Pavlov. Cond. lever latency0.20.21.01.0-0.3-0.1-0.5-0.1-0.00.2
Pavlov. Cond. magazine entry latency3.64.65.5-2.32.32.31.7-2.0-2.32.0
Pavlov. Cond. change in total contacts0.10.10.4-0.60.40.30.2-0.2-0.40.2
Pavlov. Cond. index score0.70.92.1-1.51.00.90.8-0.7-0.90.6
Pavlov. Cond. latency score0.70.92.6-1.61.00.90.9-0.6-0.80.5
Pavlov. Cond. lever contacts0.10.20.8-0.90.20.10.40.10.0-0.3
Pavlov. Cond. magazine entry number1.11.31.81.3-1.2-1.2-0.81.11.3-1.0
Pavlov. Cond. intertrial magazine entries0.20.20.50.20.20.30.0-0.7-0.50.6
Pavlov. Cond. lever-magazine prob. diff.0.91.12.2-1.51.11.00.9-0.8-1.00.7
Pavlov. Cond. response bias1.11.31.8-1.41.21.20.8-1.1-1.31.0
Pavlov. Cond. lever latency0.60.81.40.4-0.8-0.9-1.20.90.8-1.1
Pavlov. Cond. magazine entry latency0.40.50.7-0.70.70.70.8-0.6-0.80.7
Pavlov. Cond. change in total contacts0.30.61.1-0.30.70.70.9-0.9-0.61.1
Pavlov. Cond. index score0.40.71.0-0.50.80.81.0-0.9-0.81.0
Pavlov. Cond. latency score0.50.71.3-0.60.80.81.1-0.8-0.81.0
Pavlov. Cond. lever contacts0.40.61.0-0.20.70.70.9-0.9-0.81.0
Pavlov. Cond. magazine entry number0.70.81.20.8-0.9-0.9-1.10.90.9-0.9
Pavlov. Cond. intertrial magazine entries0.30.61.61.2-0.7-0.7-0.90.40.6-0.5
Pavlov. Cond. lever-magazine prob. diff.0.50.81.3-0.60.80.91.1-0.9-0.81.0
Pavlov. Cond. response bias1.31.82.7-0.71.31.31.4-1.5-1.41.6
Time in closed arm before self-admin0.30.41.0-0.0-0.5-0.6-0.20.90.8-1.0
Time in closed arm after self-admin0.10.20.3-0.10.30.40.0-0.5-0.50.5
Time in open arm before self-admin0.10.10.3-0.40.30.30.5-0.2-0.20.2
Time in open arm after self-admin1.01.21.31.1-1.1-1.1-1.01.01.0-1.1
Bone: periosteal estimation0.20.40.80.3-0.6-0.70.10.90.7-0.9
Bone: periosteal perimeter0.10.31.1-0.70.40.31.1-0.0-0.20.1
Bone: post-yield work0.50.91.11.1-1.0-1.0-0.90.90.7-0.9
Progressive ratio test 1 active lever presses0.10.10.40.30.20.3-0.3-0.5-0.60.3
Progressive ratio test 1 breakpoint0.10.10.30.40.10.2-0.3-0.5-0.60.3
Progressive ratio test 1 inactive lever presses0.10.40.7-0.40.60.60.2-0.8-0.80.4
Progressive ratio test 2 active lever presses0.20.20.50.30.30.4-0.1-0.7-0.70.5
Progressive ratio test 2 breakpoint0.20.30.70.20.40.5-0.1-0.8-0.80.6
Progressive ratio test 2 inactive lever presses0.00.10.2-0.40.40.40.2-0.4-0.40.2
Incentive Sensitization - Responses0.10.20.50.7-0.3-0.2-0.7-0.1-0.10.0
Incentive Sensitization - Breakpoint0.00.10.30.5-0.1-0.0-0.5-0.2-0.20.2
Sum of active levers in priming session hrs 5-60.00.00.10.1-0.1-0.1-0.20.20.1-0.1
Progressive ratio0.10.41.50.6-0.5-0.5-1.20.40.2-0.3
Food seeking constrained by brief footshock0.30.41.0-1.00.70.70.1-0.4-0.60.3
Seeking ratio, punishment vs. effort0.20.50.9-1.00.70.70.9-0.5-0.40.3
Retroperitoneal fat weight0.41.94.31.7-1.3-1.2-2.11.00.8-1.1
Reaction time number correct0.31.03.11.8-1.0-0.8-1.30.30.5-0.5
Reaction time mean minus median0.10.60.9-0.40.80.80.7-0.9-0.90.9
Reaction time mean minus median AUC0.00.10.2-0.20.0-0.10.50.30.1-0.2
Reaction time num false alarms0.20.31.11.0-0.6-0.5-0.50.10.2-0.2
Reaction time num false alarms AUC0.20.41.31.1-0.7-0.5-0.70.10.2-0.2
Reaction time trials correct on left0.31.03.11.8-1.0-0.8-1.30.30.5-0.5
Reaction time trials on left0.31.03.01.7-1.0-0.8-1.30.30.5-0.6
Reaction time mean0.00.10.10.2-0.2-0.30.20.30.3-0.2
Reaction time mean AUC0.00.10.20.2-0.3-0.30.20.40.4-0.3
Median of all reaction times0.20.40.60.4-0.6-0.7-0.10.70.8-0.7
Reaction time omissions0.10.20.4-0.50.40.40.7-0.2-0.20.2
Reaction time false alarm rate0.00.00.10.2-0.3-0.3-0.10.20.2-0.2
Reaction time premature initiation rate0.81.21.9-0.71.11.10.8-1.3-1.21.4
Reaction time premature initiations0.30.81.50.20.70.80.2-1.2-1.11.2
Std. dev. reaction times0.00.10.3-0.10.30.30.5-0.3-0.40.4
Reaction time trials completed0.31.03.01.7-1.0-0.8-1.30.30.5-0.6
Reaction time trials AUC0.31.03.41.8-1.0-0.8-1.40.30.4-0.5
Run reversals in cocaine runway, females0.60.71.2-1.10.90.81.0-0.6-0.80.5
Run reversals in cocaine runway, males1.82.02.6-1.61.51.51.5-1.3-1.31.1
Latency to leave start box in cocaine runway0.40.51.6-0.90.60.51.3-0.30.00.5
Latency to leave start box in cocaine runway, F0.30.31.0-0.3-0.2-0.30.80.71.0-0.4
Latency to leave start box in cocaine runway, M1.81.72.3-1.01.31.41.0-1.5-1.41.5
Std. dev. time between licks in bursts0.50.92.2-0.70.90.91.5-0.8-0.50.8
Total sessions with >9 infusions0.20.20.4-0.20.40.50.2-0.6-0.70.3
Short access day 1 total inactive lever presses0.20.40.6-0.60.60.70.3-0.7-0.80.4
Short access day 10 total inactive lever presses0.00.10.20.3-0.2-0.1-0.50.0-0.00.1
Short access day 1 total infusions0.20.40.6-0.70.70.70.5-0.7-0.80.4
Short access day 10 total infusions0.10.10.30.10.20.3-0.2-0.5-0.50.2
Short access total infusions0.20.30.5-0.40.50.60.3-0.6-0.70.5
Short access day 1 locomotion0.91.62.0-1.11.31.31.2-1.4-1.41.0
Short access day 10 total locomotion1.76.89.2-1.82.62.72.0-3.0-3.02.8
Short access total locomotion1.62.43.2-1.21.61.61.3-1.7-1.81.5
One hour access (0.3 mA shock)0.00.00.10.3-0.1-0.1-0.3-0.1-0.1-0.3
Compulsive drug intake0.91.32.20.4-1.0-1.2-0.41.41.5-1.4
One hour access (shock baseline)0.20.61.3-0.20.70.80.3-1.1-1.10.7
Social response proportion0.81.01.4-1.21.11.01.1-0.9-0.70.9
Social responses7.19.311.4-3.23.13.03.4-2.8-2.82.9
Social time0.40.60.90.6-0.8-0.8-0.90.81.0-0.7
Soleus weight8.625.327.35.1-5.2-5.2-4.75.04.9-5.1
Bone: stiffness2.34.15.51.7-2.1-2.1-1.52.32.1-2.2
Tibialis anterior weight1.13.74.02.0-2.0-2.0-1.91.91.7-2.0
Time to tail flick, vehicle, before self-admin0.10.10.3-0.50.30.30.3-0.2-0.20.1
Time to tail flick, vehicle, after self-admin0.20.50.90.00.50.7-0.1-0.9-1.01.0
Time to tail flick, test, before self-admin0.30.40.9-0.90.60.50.9-0.4-0.40.3
Time to tail flick, test, after self-admin0.10.10.2-0.40.40.40.2-0.4-0.40.3
Delta time to tail flick, vehicle, before/after SA0.30.31.01.0-0.5-0.3-1.00.0-0.00.0
Delta time to tail flick, test, before/after SA0.10.10.40.4-0.00.1-0.6-0.3-0.30.3
Tibia length0.82.32.8-1.31.51.51.4-1.7-1.61.6
Ambulatory time before self-admin0.10.20.40.4-0.5-0.5-0.20.60.6-0.6
Ambulatory time after self-admin0.00.00.0-0.0-0.0-0.00.10.10.1-0.1
Bone: tissue strength1.92.02.41.1-1.4-1.5-1.21.51.5-1.5
Total heroin consumption1.61.92.5-1.61.51.41.4-1.3-1.31.2
Bone: trabecular number0.50.92.3-1.50.90.81.4-0.5-0.50.4
Bone: trabecular spacing0.81.13.61.9-0.9-0.7-1.70.10.2-0.2
Bone: trabecular thickness0.60.82.2-1.2-0.0-0.31.50.91.0-0.7
Bone: trabecular tissue density1.22.02.81.5-1.5-1.4-1.71.41.3-1.3
Water consumed over 24 hours0.50.91.20.8-1.0-1.0-0.51.11.1-1.1
Number of responses in last shaping day1.31.72.4-1.01.31.41.0-1.5-1.61.3