Hub : Genes

Atp5f1b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Atp5f1b 0.21 0.12 0.0e+00 0.17 0.17 0.17 0.17 5.2e-16 2.7e-15 7.8e-16 7.2e-16
2 BLA gene expression Atp5f1b 0.17 0.11 8.0e-10 0.19 0.19 0.19 0.19 1.3e-10 1.9e-10 1.7e-10 1.2e-10
3 NAcc gene expression Atp5f1b 0.07 0.05 1.9e-08 0.06 0.05 0.06 0.06 8.5e-08 6.6e-07 1.2e-07 5.2e-07
4 Liver gene expression Atp5f1b 0.13 0.08 6.9e-15 0.12 0.12 0.12 0.12 1.8e-13 2.9e-13 2.7e-13 3.2e-13
5 PL gene expression Atp5f1b 0.05 0.04 4.1e-06 0.05 0.05 0.04 0.05 4.7e-06 4.4e-06 1.6e-05 4.5e-06
6 IL gene expression Atp5f1b 0.16 0.12 8.4e-03 0.02 0.01 0 0 1.0e-01 2.1e-01 3.2e-01 3.2e-01
7 Adipose mRNA stability Atp5f1b 0.08 0.06 5.2e-08 0.06 0.06 0.07 0.07 5.8e-07 3.0e-07 3.5e-08 7.3e-08
8 Adipose gene expression Atp5f1b 0.24 0.15 0.0e+00 0.14 0.15 0.15 0.15 1.6e-15 5.1e-16 1.7e-16 3.7e-16

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bone: apparent density1.01.64.0-0.91.0-1.0-1.01.10.8-2.0-1.8
Area under the delay curve0.10.10.2-0.20.2-0.3-0.10.2-0.1-0.4-0.4
BMI with tail6.922.227.45.2-5.14.95.0-4.85.13.63.8
BMI without tail1.53.23.81.7-1.91.92.0-1.91.61.61.7
Body weight1.04.35.22.0-2.22.22.3-2.22.31.61.7
Weight adjusted by age0.10.10.40.2-0.40.30.4-0.3-0.20.60.5
Bone surface2.54.49.9-1.71.9-1.8-1.82.00.9-3.1-2.8
Bone volume2.33.99.2-1.51.6-1.6-1.61.81.1-3.0-2.7
Breakpoint value in progressive ratio session1.41.52.8-1.41.3-1.3-1.31.2-1.7-0.5-0.7
Number of licking bursts4.35.06.12.5-2.32.22.3-2.31.72.32.2
Context. condit. distance diff. score0.20.30.40.5-0.50.60.6-0.50.50.50.5
Locomotion velocity, session 10.40.40.9-0.90.4-0.4-0.30.50.5-1.0-0.9
Locomotion distance, session 11.01.22.4-0.91.1-1.0-1.01.10.1-1.6-1.5
Locomotion velocity, session 22.83.35.0-2.11.8-1.7-1.71.9-0.5-2.2-2.1
Locomotion distance, session 24.36.07.2-2.32.6-2.5-2.52.6-1.4-2.7-2.7
Locomotion velocity, session 34.35.06.6-2.62.4-2.3-2.32.3-2.5-1.7-1.7
Locomotion distance, session 30.00.00.1-0.10.4-0.2-0.20.2-0.4-0.00.0
Stereotopy head waving bouts, day 35.66.67.5-2.72.7-2.7-2.72.7-2.5-2.2-2.4
Stereotopy head waving duration, day 33.44.14.8-2.22.1-2.1-2.12.1-1.9-1.8-1.8
Locomotion velocity, session 70.20.20.5-0.20.4-0.4-0.40.4-0.1-0.7-0.5
Locomotion distance, session 70.40.40.80.9-0.60.50.6-0.70.10.80.8
Stereotopy head waving bouts, day 71.71.92.7-1.31.4-1.4-1.41.5-0.7-1.6-1.6
Stereotopy head waving duration, day 71.82.23.2-1.61.4-1.5-1.41.5-0.6-1.8-1.8
Locomotion velocity, session 83.13.75.4-2.22.0-1.8-1.82.0-0.8-2.3-2.2
Locomotion distance, session 80.50.81.0-0.81.0-0.9-0.90.9-0.6-0.9-0.9
Degree of sensitization distance0.50.50.80.9-0.80.70.7-0.70.80.50.5
Degree of sensitization stereotypy0.10.10.4-0.10.2-0.2-0.20.30.4-0.6-0.6
Conditioned locomotion1.92.23.21.6-1.51.51.5-1.50.51.81.7
Cocaine response after cond. corrected3.64.15.31.8-2.32.12.1-2.11.22.22.2
Cocaine response after cond. not corrected4.04.45.62.0-2.42.12.2-2.21.22.22.3
Cocaine response before conditioning0.60.80.9-0.80.9-1.0-1.00.9-0.7-0.9-0.9
Saline control response0.40.60.70.6-0.80.80.8-0.80.60.70.8
Bone: connectivity density0.61.02.2-0.80.8-0.8-0.80.90.6-1.5-1.4
Bone: cortical apparent density1.31.72.31.0-1.51.51.4-1.41.51.11.1
Bone: cortical area0.40.63.10.6-0.50.50.4-0.41.8-0.4-0.3
Bone: cortical porosity0.10.10.3-0.10.4-0.3-0.30.30.2-0.6-0.5
Bone: cortical porosity0.10.20.60.10.2-0.1-0.10.10.8-0.6-0.5
Bone: cortical thickness0.91.43.71.3-1.21.21.1-1.11.90.50.6
Bone: cortical thickness1.01.21.41.2-1.01.21.1-1.20.91.21.1
Bone: cortical tissue density1.01.31.60.7-1.31.31.2-1.21.31.01.0
Condit. Reinf. active minus inactive responses1.82.02.7-1.41.6-1.4-1.41.5-1.4-1.3-1.2
Condit. Reinf. active-inactive response ratio0.10.10.3-0.10.4-0.2-0.20.2-0.6-0.00.1
Condit. Reinf. active responses3.34.15.1-2.02.3-2.1-2.12.1-1.5-2.0-2.0
Condit. Reinf. inactive responses2.42.83.7-1.61.8-1.7-1.81.8-1.0-1.8-1.9
Incentive salience index mean1.92.22.8-1.61.7-1.5-1.51.6-0.9-1.6-1.5
Condit. Reinf. lever presses1.52.03.7-1.51.4-1.2-1.21.4-0.0-1.9-1.8
Condit. Reinf. active minus inactive responses0.91.13.3-1.01.0-1.1-1.11.0-1.8-0.2-0.4
Condit. Reinf. active-inactive response ratio0.30.31.5-0.1-0.1-0.1-0.0-0.1-1.20.80.7
Condit. Reinf. active responses0.91.21.9-1.01.2-1.2-1.21.1-1.4-0.7-0.8
Condit. Reinf. inactive responses0.50.60.9-0.60.9-0.8-0.80.8-0.3-0.9-0.9
Condit. Reinf. lever presses1.62.14.8-1.41.6-1.5-1.51.4-2.2-0.6-0.8
Condit. Reinf. lever reinforcers received0.50.71.7-0.80.9-0.9-0.90.8-1.3-0.4-0.5
Conditioned reinforcement - actives0.10.10.3-0.30.1-0.3-0.30.30.3-0.6-0.5
Conditioned reinforcement - inactives2.12.42.81.3-1.61.71.7-1.61.01.71.6
Conditioned locomotion1.92.22.7-1.31.6-1.6-1.61.6-1.5-1.4-1.4
Patch foraging indifference point 0 sec3.04.87.62.6-2.22.32.2-2.22.81.41.5
Patch foraging indifference point AUC0.40.40.8-0.60.7-0.8-0.60.7-0.9-0.4-0.4
Delay disc. indifference point, 0s delay0.40.41.90.4-0.30.30.4-0.21.4-0.8-0.6
Delay disc. indifference point, 16s delay0.40.40.6-0.60.5-0.8-0.60.6-0.7-0.7-0.6
Delay disc. indifference point, 2s delay0.00.00.20.3-0.0-0.10.10.00.5-0.1-0.1
Delay disc. indifference point, 24s delay0.10.10.30.6-0.30.20.3-0.30.30.00.1
Delay disc. indifference point, 4s delay0.90.91.4-0.81.0-1.1-1.01.0-0.5-1.2-1.2
Delay disc. indifference point, 8s delay0.20.20.20.2-0.40.30.5-0.5-0.20.50.5
Indifference point function ln k0.20.20.30.4-0.40.60.5-0.50.60.30.4
Indifference point function log k0.20.20.30.4-0.40.60.5-0.50.60.30.4
Patch foraging total patch changes 0 sec3.04.97.32.7-2.22.32.3-2.22.61.51.6
Patch foraging total patch changes 12 sec2.43.24.62.1-1.71.81.9-1.81.41.81.7
Patch foraging total patch changes 18 sec0.00.00.10.2-0.20.10.2-0.20.10.10.2
Patch foraging total patch changes 24 sec0.30.30.80.7-0.50.60.6-0.50.90.20.3
Patch foraging total patch changes 6 sec1.82.74.02.0-1.61.71.7-1.61.91.21.2
Patch foraging time to switch 0 sec0.10.10.50.0-0.20.20.1-0.10.7-0.3-0.2
Patch foraging water rate 0 sec1.01.52.01.2-1.21.31.4-1.30.71.41.4
Patch foraging water rate 12 sec1.42.12.61.4-1.51.51.5-1.50.81.61.6
Patch foraging water rate 18 sec0.81.12.60.6-0.70.90.8-1.0-0.51.61.5
Patch foraging water rate 24 sec3.65.08.22.1-2.12.22.2-2.30.52.92.7
Patch foraging water rate 6 sec0.10.20.9-0.20.00.10.0-0.1-0.90.60.6
Seeking ratio, delayed vs. immediate footshock1.61.92.3-1.51.4-1.4-1.41.4-0.8-1.4-1.4
Distance traveled before self-admin0.91.01.6-0.61.3-1.1-1.21.1-1.0-0.8-0.9
Distance traveled after self-admin0.20.20.4-0.30.6-0.5-0.60.5-0.4-0.2-0.5
Extensor digitorum longus weight5.822.827.14.5-5.15.25.2-5.04.34.34.5
Bone: elastic displacement0.00.00.00.1-0.0-0.1-0.10.10.1-0.1-0.2
Bone: elastic work0.30.41.30.8-0.60.50.4-0.51.10.00.1
Bone: endosteal estimation0.30.82.50.9-0.90.80.8-0.71.60.00.3
Bone: endosteal perimeter0.51.01.9-0.71.0-1.1-0.91.0-0.1-1.4-1.2
Epididymis fat weight0.00.10.30.10.2-0.3-0.30.2-0.60.00.0
Delta time in closed arm before/after self-admin3.33.25.81.8-1.71.71.7-1.80.32.42.3
Delta time in open arm before/after self-admin0.50.51.40.6-0.60.80.8-0.71.20.20.4
Diff in mean of infusions in LGA sessions1.51.62.6-1.21.4-1.4-1.41.3-1.6-0.9-1.0
Delay discount exponential model param0.10.10.10.2-0.20.40.2-0.20.20.40.3
Extinction: sum of active levers before priming1.51.55.0-1.21.2-1.2-1.21.1-2.2-0.3-0.4
Active lever presses in extinction session 61.51.41.7-1.01.3-1.2-1.31.2-1.1-1.1-1.2
Bone: final force1.32.16.41.7-1.41.41.3-1.32.50.40.6
Bone: final moment1.32.06.21.7-1.31.31.3-1.32.50.30.5
Food consumed during 24 hour testing period0.40.51.21.1-0.60.60.7-0.70.70.50.5
Glucose1.62.53.01.7-1.61.71.7-1.61.71.21.3
Heart weight0.10.20.30.2-0.50.40.5-0.40.10.50.6
Delay discount hyperbolic model param0.00.00.1-0.1-0.10.20.0-0.1-0.00.20.2
Intermittent access intake day 1-15 change0.00.00.2-0.10.3-0.2-0.20.2-0.4-0.0-0.0
Intermittent access intake escalation0.30.30.70.4-0.30.40.4-0.4-0.50.80.8
Intermittent access intake escalation 20.20.21.0-0.10.1-0.1-0.10.1-1.00.40.2
Intermitt. access day 1 inactive lever presses0.40.40.90.4-0.60.50.5-0.5-0.50.90.8
Intermitt. access day 15 inactive lever presses0.30.31.3-0.70.5-0.4-0.40.4-1.20.1-0.1
Intermitt. access escalation Index0.60.61.2-0.80.7-0.6-0.60.70.4-1.1-0.9
Intermittent access day 1 total infusions0.20.20.60.2-0.50.50.5-0.50.80.20.3
Intermittent access day 15 total infusions0.30.30.40.5-0.50.60.6-0.60.40.60.6
Intermittent access terminal intake (last 3 days)0.10.10.60.1-0.30.30.3-0.30.8-0.00.1
Intermittent access total infusions0.40.40.60.6-0.70.70.7-0.70.80.60.6
Intermittent access day 1 locomotion0.00.00.0-0.2-0.10.10.1-0.1-0.00.20.1
Intermittent access day 15 total locomotion0.10.20.5-0.70.3-0.3-0.30.3-0.5-0.1-0.2
Intermittent access total locomotion0.20.30.6-0.80.5-0.5-0.50.5-0.4-0.4-0.5
Intermittent access standard deviation0.00.00.10.00.10.00.0-0.0-0.30.20.2
Left kidney weight0.10.41.0-0.50.1-0.3-0.20.40.8-1.0-0.9
Right kidney weight0.31.01.6-1.20.9-1.0-0.81.0-0.4-1.2-1.1
Cocaine induced anxiety2.52.93.5-1.81.7-1.8-1.81.8-1.1-1.9-1.9
Post-drug Anxiety1.61.83.2-1.21.3-1.2-1.21.3-0.1-1.8-1.7
Baseline Anxiety0.10.10.10.2-0.10.20.2-0.30.00.40.3
Tail length3.610.816.9-3.73.5-3.3-3.43.3-4.1-2.2-2.3
Length with tail1.76.28.5-2.92.7-2.5-2.62.5-2.5-2.0-2.1
Length without tail0.10.10.5-0.0-0.1-0.1-0.10.10.7-0.5-0.5
Times rat made contact with spout1.41.62.01.4-1.31.31.3-1.30.91.31.3
Lifetime Intake0.70.82.00.8-0.90.90.9-0.91.40.50.6
Liver weight, left2.03.24.12.0-1.81.81.9-1.81.51.61.7
Liver weight, right0.71.21.70.9-1.31.21.2-1.11.30.80.8
Locomotor activity4.57.18.8-3.02.9-2.6-2.82.7-2.1-2.6-2.5
Locomotor testing distance1.62.63.3-1.71.8-1.7-1.61.7-1.3-1.6-1.5
Locomotor testing rearing0.00.00.10.0-0.00.00.1-0.1-0.30.30.3
Locomotion in novel chamber0.40.50.80.9-0.70.60.7-0.60.60.70.7
Locomotion in novel chamber post-restriction2.73.34.6-1.61.9-2.1-1.91.9-2.1-1.3-1.4
Fecal boli incidents, locomotor time 11.21.32.41.0-1.21.11.1-1.20.41.51.4
Change in fecal boli incidents, locomotor task1.51.42.5-1.11.2-0.9-1.11.2-0.0-1.6-1.5
Time >=10cm from walls, locomotor time 10.20.20.80.3-0.40.20.3-0.20.9-0.3-0.3
Bouts of movement, locomotor time 10.40.41.0-0.60.5-0.8-0.60.6-1.0-0.4-0.4
Total resting periods, locomotor time 11.11.21.9-1.21.0-1.3-1.11.0-1.4-0.8-0.8
Rest time, locomotor task time 10.70.81.0-1.00.8-1.0-0.90.9-0.8-0.8-0.8
Distance moved, locomotor task time 10.40.42.00.5-0.30.60.4-0.31.4-0.2-0.2
Vertical activity count, locomotor time 11.41.52.11.2-1.21.41.3-1.31.30.91.0
Time >=10cm from walls, locomotor time 21.51.61.91.2-1.41.21.3-1.30.91.31.3
Bouts of movement, locomotor time 21.11.22.1-1.30.9-1.2-0.91.0-0.6-1.4-1.3
Total resting periods, locomotor time 21.21.32.3-1.30.9-1.2-0.91.0-0.4-1.5-1.4
Rest time, locomotor task time 20.30.40.7-0.50.5-0.6-0.50.6-0.0-0.9-0.8
Distance moved, locomotor task time 20.30.40.60.5-0.50.70.5-0.60.10.80.8
Vertical activity count, locomotor time 22.22.43.01.2-1.51.71.7-1.70.91.61.7
Light reinforcement 13.46.27.4-2.62.7-2.6-2.62.6-2.4-2.3-2.2
Light reinforcement 20.91.11.6-0.91.2-1.1-1.31.1-1.1-0.9-1.0
Bone: marrow area0.30.72.20.9-0.90.70.8-0.71.50.00.2
Bone: maximum diameter0.91.63.2-1.31.1-1.2-1.21.30.0-1.8-1.6
Bone: maximum force1.52.77.01.8-1.71.61.5-1.52.70.60.8
Bone: maximum moment1.52.66.91.8-1.61.61.5-1.52.60.50.8
Mean time between licks in bursts0.30.41.3-0.50.7-0.7-0.70.6-1.1-0.1-0.2
Mean num. licks in bursts1.01.21.3-1.11.1-1.1-1.11.1-0.9-1.2-1.0
Cd content in liver0.50.51.51.2-0.70.60.7-0.70.60.50.5
Co content in liver0.60.71.8-1.20.8-0.8-0.80.7-1.3-0.2-0.3
Cu content in liver0.50.62.50.7-0.70.70.7-0.51.6-0.1-0.1
Fe content in liver0.81.01.31.1-1.10.91.1-1.00.61.01.0
K content in liver1.01.01.6-0.81.0-1.1-0.91.0-0.5-1.3-1.2
Mg content in liver1.01.01.9-0.71.0-1.1-0.91.1-0.3-1.4-1.4
Mn content in liver2.32.65.3-1.01.4-1.6-1.41.60.1-2.3-2.3
Na content in liver0.10.10.2-0.10.1-0.2-0.10.20.3-0.5-0.5
Rb content in liver0.30.31.60.5-0.40.40.4-0.31.3-0.4-0.3
Se content in liver0.10.10.1-0.30.2-0.3-0.20.3-0.2-0.3-0.3
Sr content in liver0.20.20.70.1-0.10.20.1-0.3-0.50.80.8
Zn content in liver0.70.83.8-0.80.7-0.8-0.70.5-1.90.40.3
Bone: minimum diameter0.10.21.20.2-0.20.10.2-0.11.1-0.6-0.4
Time in familiar zone, hab. session 13.63.36.2-1.42.0-2.0-2.01.8-2.5-1.1-1.2
Time in novel zone, hab. session 11.81.85.31.1-1.41.41.4-1.22.30.30.4
Total zone transitions, hab. session 11.21.72.6-1.11.4-1.3-1.31.3-0.4-1.6-1.6
Total locomotion distance, hab. session 13.65.17.2-2.12.4-2.3-2.22.4-0.9-2.7-2.7
Locomotion velocity, hab. session 13.34.65.8-2.22.3-2.2-2.12.2-1.1-2.4-2.4
Time in familiar zone, hab. session 22.82.96.6-1.81.7-1.8-1.81.6-2.6-0.9-0.9
Time in novel zone, hab. session 23.03.07.51.8-1.81.81.8-1.62.70.80.8
Total zone transitions, hab. session 20.30.41.4-0.20.2-0.00.00.21.2-1.0-0.8
Total locomotion distance, hab. session 21.11.42.1-1.41.2-1.1-1.11.2-0.3-1.5-1.4
Locomotion velocity, hab. session 21.52.03.1-1.61.4-1.3-1.21.4-0.3-1.8-1.7
Novel to familiar place preference ratio1.11.24.41.0-0.81.11.2-0.92.10.10.2
Novelty place preference0.70.73.00.8-0.50.80.9-0.61.7-0.00.0
Time in novel zone, NPP test1.11.13.91.1-0.81.11.2-0.92.00.20.3
Total zone transitions, NPP test0.10.10.60.2-0.00.10.1-0.10.8-0.4-0.3
Total locomotion distance, NPP test0.30.40.9-0.60.5-0.4-0.40.50.5-1.0-0.9
Locomotion velocity, NPP test0.50.71.3-0.90.7-0.7-0.70.80.1-1.1-1.1
Intraocular pressure0.20.31.4-0.30.2-0.3-0.20.1-1.20.50.5
Delta distance traveled before/after self-admin0.00.00.1-0.2-0.20.10.1-0.10.30.30.1
Delta ambulatory time before/after self-admin0.00.00.2-0.2-0.0-0.0-0.00.10.4-0.1-0.2
Parametrial fat weight0.00.00.10.3-0.1-0.1-0.20.0-0.40.20.0
Pavlov. Cond. lever latency0.60.71.31.1-0.70.70.6-0.8-0.11.11.1
Pavlov. Cond. magazine entry latency1.11.52.3-1.51.2-1.2-1.21.2-1.5-0.8-0.8
Pavlov. Cond. change in total contacts0.10.10.30.2-0.20.40.5-0.30.60.20.2
Pavlov. Cond. index score0.91.11.9-1.41.1-1.0-0.91.1-0.5-1.1-1.1
Pavlov. Cond. latency score1.21.52.5-1.61.2-1.1-1.11.2-0.4-1.4-1.4
Pavlov. Cond. lever contacts0.70.81.6-1.10.8-0.7-0.60.80.3-1.3-1.2
Pavlov. Cond. magazine entry number0.50.61.11.1-0.80.80.7-0.80.80.60.6
Pavlov. Cond. intertrial magazine entries0.10.10.40.20.00.20.1-0.2-0.40.60.6
Pavlov. Cond. lever-magazine prob. diff.1.01.21.9-1.41.2-1.1-1.01.1-0.6-1.2-1.1
Pavlov. Cond. response bias0.70.91.3-1.11.0-1.0-0.91.0-0.9-0.8-0.8
Pavlov. Cond. lever latency1.52.02.61.4-1.61.51.5-1.41.51.11.1
Pavlov. Cond. magazine entry latency2.32.63.1-1.61.8-1.7-1.81.7-1.6-1.4-1.4
Pavlov. Cond. change in total contacts0.50.71.1-0.71.0-0.9-0.90.8-1.0-0.5-0.6
Pavlov. Cond. index score1.72.22.8-1.41.7-1.6-1.61.5-1.7-1.1-1.2
Pavlov. Cond. latency score2.12.63.3-1.51.8-1.7-1.71.7-1.7-1.3-1.4
Pavlov. Cond. lever contacts1.01.32.3-1.11.3-1.2-1.21.1-1.5-0.7-0.8
Pavlov. Cond. magazine entry number2.02.42.91.5-1.71.71.7-1.61.51.31.4
Pavlov. Cond. intertrial magazine entries1.01.31.70.6-1.21.31.3-1.20.91.21.3
Pavlov. Cond. lever-magazine prob. diff.1.82.32.9-1.51.7-1.7-1.71.6-1.6-1.2-1.3
Pavlov. Cond. response bias1.52.13.4-1.51.6-1.5-1.61.4-1.8-0.9-1.0
Time in closed arm before self-admin0.20.20.4-0.50.1-0.3-0.20.30.7-0.5-0.5
Time in closed arm after self-admin0.40.40.70.4-0.60.60.6-0.50.70.80.7
Time in open arm before self-admin0.10.10.30.30.1-0.1-0.10.0-0.5-0.1-0.1
Time in open arm after self-admin1.11.22.21.5-1.11.21.2-1.20.90.50.8
Bone: periosteal estimation0.40.94.40.8-0.80.70.7-0.62.1-0.4-0.1
Bone: periosteal perimeter0.30.51.3-0.20.5-0.6-0.50.60.7-1.2-1.0
Bone: post-yield work0.30.40.60.3-0.70.70.6-0.60.80.30.5
Progressive ratio test 1 active lever presses1.31.41.81.0-1.21.31.3-1.21.31.01.1
Progressive ratio test 1 breakpoint1.31.42.01.1-1.21.31.3-1.21.40.91.0
Progressive ratio test 1 inactive lever presses0.00.00.1-0.2-0.00.10.1-0.00.4-0.1-0.0
Progressive ratio test 2 active lever presses0.40.50.90.3-0.70.70.7-0.71.00.40.5
Progressive ratio test 2 breakpoint0.10.10.6-0.3-0.10.20.2-0.10.8-0.3-0.1
Progressive ratio test 2 inactive lever presses0.10.20.80.1-0.30.40.4-0.30.9-0.00.1
Incentive Sensitization - Responses0.10.10.3-0.60.2-0.3-0.30.3-0.2-0.3-0.3
Incentive Sensitization - Breakpoint0.20.20.5-0.70.4-0.4-0.40.5-0.2-0.5-0.5
Sum of active levers in priming session hrs 5-60.20.20.4-0.10.6-0.5-0.50.4-0.60.1-0.1
Progressive ratio1.31.62.01.1-1.31.41.3-1.31.21.21.2
Food seeking constrained by brief footshock1.51.82.7-1.21.4-1.5-1.41.4-1.7-1.0-1.1
Seeking ratio, punishment vs. effort2.22.73.7-1.51.7-1.8-1.71.7-1.9-1.3-1.3
Retroperitoneal fat weight2.37.79.22.7-3.03.03.0-2.92.82.32.5
Reaction time number correct1.62.44.22.0-1.41.51.4-1.50.71.71.6
Reaction time mean minus median1.92.54.8-2.21.6-1.4-1.61.5-1.3-1.5-1.3
Reaction time mean minus median AUC3.24.26.1-2.52.1-1.9-2.02.1-0.9-2.4-2.2
Reaction time num false alarms0.60.81.10.7-0.91.01.0-1.00.81.00.9
Reaction time num false alarms AUC0.91.21.60.8-1.11.31.2-1.20.81.21.2
Reaction time trials correct on left1.62.44.22.0-1.41.51.4-1.50.71.71.6
Reaction time trials on left1.52.24.02.0-1.41.41.4-1.50.71.61.5
Reaction time mean1.92.74.2-2.01.5-1.7-1.61.7-1.0-1.7-1.6
Reaction time mean AUC1.11.52.6-1.61.0-1.2-1.11.2-0.5-1.4-1.3
Median of all reaction times1.01.42.2-1.51.0-1.3-1.11.2-0.7-1.3-1.3
Reaction time omissions0.00.00.1-0.10.0-0.2-0.10.20.2-0.3-0.2
Reaction time false alarm rate0.10.10.2-0.3-0.20.30.3-0.20.50.10.1
Reaction time premature initiation rate0.71.03.2-1.30.9-0.9-0.90.8-1.8-0.2-0.2
Reaction time premature initiations0.30.41.9-0.10.1-0.1-0.1-0.0-1.40.70.7
Std. dev. reaction times1.41.93.4-1.81.3-1.3-1.31.4-0.9-1.5-1.3
Reaction time trials completed1.52.24.02.0-1.41.41.4-1.50.71.61.5
Reaction time trials AUC1.92.74.72.2-1.51.61.5-1.70.71.81.7
Run reversals in cocaine runway, females2.12.02.4-1.31.5-1.6-1.61.5-1.3-1.3-1.4
Run reversals in cocaine runway, males2.72.63.2-1.61.6-1.8-1.61.7-1.3-1.6-1.5
Latency to leave start box in cocaine runway0.40.51.1-0.50.6-0.4-0.50.50.8-1.1-1.0
Latency to leave start box in cocaine runway, F0.70.82.0-0.40.6-0.6-0.60.71.0-1.4-1.2
Latency to leave start box in cocaine runway, M0.20.20.50.1-0.20.60.2-0.5-0.10.70.6
Std. dev. time between licks in bursts0.91.11.7-0.81.1-1.0-1.01.1-0.3-1.2-1.3
Total sessions with >9 infusions0.30.31.60.1-0.0-0.0-0.00.11.3-0.8-0.5
Short access day 1 total inactive lever presses0.00.00.10.0-0.10.10.1-0.10.3-0.0-0.0
Short access day 10 total inactive lever presses0.30.30.70.2-0.60.50.5-0.5-0.10.80.7
Short access day 1 total infusions0.50.53.10.1-0.30.40.4-0.31.8-0.5-0.2
Short access day 10 total infusions0.60.71.40.8-0.80.90.9-0.91.20.50.6
Short access total infusions0.80.94.10.7-0.80.90.9-0.82.00.00.3
Short access day 1 locomotion0.20.20.4-0.60.4-0.4-0.40.40.2-0.6-0.5
Short access day 10 total locomotion0.60.72.1-1.00.6-0.8-0.80.8-1.4-0.2-0.4
Short access total locomotion0.20.20.3-0.50.4-0.4-0.40.4-0.2-0.5-0.5
One hour access (0.3 mA shock)0.40.40.70.5-0.90.60.6-0.70.80.50.5
Compulsive drug intake0.10.10.20.3-0.40.30.3-0.30.50.20.2
One hour access (shock baseline)0.40.40.70.8-0.60.60.6-0.70.20.70.7
Social response proportion1.31.41.8-1.21.1-1.3-1.21.3-1.0-1.2-1.2
Social responses10.113.014.9-3.83.7-3.8-3.93.7-3.3-3.3-3.3
Social time1.01.31.91.0-1.21.41.2-1.21.11.01.1
Soleus weight5.215.118.63.3-4.24.34.3-4.14.33.13.3
Bone: stiffness2.94.59.42.1-2.22.22.2-2.13.11.21.4
Tibialis anterior weight1.03.54.41.8-2.02.12.1-1.92.11.31.6
Time to tail flick, vehicle, before self-admin2.52.63.5-1.91.6-1.8-1.71.8-0.6-1.4-1.6
Time to tail flick, vehicle, after self-admin0.10.10.7-0.10.1-0.1-0.10.0-0.80.10.2
Time to tail flick, test, before self-admin2.22.23.6-1.91.2-1.4-1.31.5-0.5-1.9-1.6
Time to tail flick, test, after self-admin0.40.50.8-0.60.6-0.7-0.70.70.1-0.9-0.8
Delta time to tail flick, vehicle, before/after SA1.91.92.41.6-1.51.41.4-1.50.21.41.5
Delta time to tail flick, test, before/after SA0.20.20.50.4-0.00.0-0.0-0.1-0.60.70.5
Tibia length0.92.54.1-1.91.6-1.5-1.61.5-2.0-1.0-1.1
Ambulatory time before self-admin0.30.30.5-0.10.7-0.6-0.60.5-0.5-0.5-0.5
Ambulatory time after self-admin0.00.10.1-0.00.4-0.2-0.30.2-0.10.0-0.3
Bone: tissue strength3.33.25.32.2-1.91.81.8-1.82.31.11.2
Total heroin consumption2.52.93.5-1.51.8-1.9-1.91.8-1.7-1.5-1.5
Bone: trabecular number1.82.84.3-1.51.7-1.7-1.71.7-0.5-2.1-2.0
Bone: trabecular spacing2.02.65.31.4-1.51.51.5-1.6-0.32.32.1
Bone: trabecular thickness2.12.56.3-1.11.3-1.1-1.11.31.3-2.5-2.2
Bone: trabecular tissue density6.49.110.52.8-3.23.23.2-3.22.72.82.9
Water consumed over 24 hours0.30.41.70.7-0.50.50.5-0.41.3-0.1-0.2
Number of responses in last shaping day0.60.71.2-1.10.8-0.8-0.80.8-0.7-0.7-0.7