Hub : Genes

Atg7

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Eye gene expression Atg7 0.41 0.2 6.3e-03 -0.01 -0.02 0.01 -0.02 4.7e-01 6.6e-01 2.2e-01 8.3e-01
2 pVTA isoform ratio XM_063286089.1 0.04 0.03 7.6e-03 0.01 0.03 0.02 0.02 2.3e-02 1.0e-03 1.2e-02 7.4e-03
3 Adipose mRNA stability Atg7 0.04 0.03 1.4e-05 0.01 0.04 0.02 0.03 1.5e-02 7.9e-05 1.5e-03 6.2e-04
4 Liver gene expression Atg7 0.14 0.06 0.0e+00 0.19 0.18 0.18 0.18 7.3e-21 3.3e-19 1.1e-19 3.6e-20
5 Liver mRNA stability Atg7 0.03 0.02 1.4e-04 0.03 0.04 0.03 0.04 1.7e-04 4.0e-05 1.3e-04 6.0e-05
6 pVTA gene expression Atg7 0.04 0.03 1.8e-04 0.07 0.05 0.04 0.06 3.2e-06 1.4e-04 3.2e-04 1.6e-05
7 Liver alternative TSS XM_063286089.1 0.02 0.02 6.1e-03 0.02 0.01 0.01 0.02 2.3e-03 1.4e-02 4.2e-02 5.3e-03
8 Adipose alternative polyA XM_008763239.4 0.04 0.02 7.3e-05 0.04 0.03 0.03 0.03 7.9e-05 1.6e-04 5.9e-04 2.9e-04
9 Adipose alternative polyA XM_063286089.1 0.04 0.02 8.3e-05 0.03 0.03 0.03 0.03 1.1e-04 2.2e-04 7.9e-04 4.2e-04
10 Adipose alternative polyA XM_008763239.4 0.03 0.02 1.9e-04 0.03 0.03 0.02 0.03 2.5e-04 5.3e-04 2.1e-03 5.3e-04
11 Adipose alternative polyA XM_063286089.1 0.03 0.02 1.8e-04 0.03 0.03 0.02 0.03 2.8e-04 5.9e-04 2.5e-03 6.0e-04
12 Adipose isoform ratio XM_008763239.4 0.05 0.03 3.3e-06 0.05 0.05 0.05 0.05 1.2e-06 4.2e-06 3.1e-06 3.1e-06
13 IL gene expression Atg7 0.19 0.12 3.9e-03 0.05 0.08 0.07 0.06 2.7e-02 4.9e-03 1.0e-02 1.3e-02
14 Adipose gene expression Atg7 0.11 0.06 1.1e-06 0.01 0.04 0.04 0.03 1.8e-02 1.5e-05 1.0e-05 2.8e-04
15 NAcc alternative TSS XM_063286089.1 0.03 0.02 7.2e-04 0 0.01 0 0 1.6e-01 6.0e-03 5.4e-02 1.3e-01
16 NAcc alternative TSS NM_001012097.1 0.03 0.02 6.7e-04 0 0.01 0.01 0 1.6e-01 5.1e-03 1.9e-02 1.0e-01
17 Liver isoform ratio NM_001012097.1 0.03 0.02 5.8e-04 0.03 0.03 0.03 0.03 6.8e-04 1.8e-04 4.4e-04 4.4e-04
18 Liver intron excision ratio chr4_149513607_149597306 0.05 0.03 5.2e-06 0.05 0.04 0.04 0.04 2.4e-06 2.7e-05 1.3e-05 1.5e-05
19 Liver isoform ratio XM_063286089.1 0.07 0.04 3.4e-08 0.08 0.07 0.08 0.08 7.1e-09 1.2e-08 9.3e-09 8.2e-09
20 NAcc gene expression Atg7 0.06 0.03 4.1e-09 0.06 0.06 0.06 0.06 8.2e-09 2.6e-09 6.9e-09 1.0e-08
21 Brain gene expression Atg7 0.2 0.09 7.6e-15 0.15 0.16 0.15 0.16 7.9e-14 4.1e-15 3.0e-14 1.3e-14
22 PL gene expression Atg7 0.16 0.07 0.0e+00 0.15 0.19 0.18 0.18 1.6e-16 5.3e-20 5.4e-19 2.6e-19
23 BLA gene expression Atg7 0.33 0.1 0.0e+00 0.22 0.36 0.37 0.36 8.6e-12 2.8e-20 2.0e-20 5.6e-20
24 IC gene expression Atg7 0.2 0.09 5.2e-05 0.05 0.09 0.08 0.05 3.5e-03 1.0e-04 2.5e-04 2.6e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density0.40.61.7-1.30.70.10.90.41.20.0-0.90.9-0.90.9-0.9-0.91.30.8-0.90.9-0.1-0.1-0.60.1-0.6-0.4-1.2
Area under the delay curve0.10.10.40.1-0.1-0.00.10.30.10.1-0.10.1-0.10.1-0.1-0.2-0.50.3-0.40.4-0.6-0.6-0.3-0.4-0.4-0.4-0.4
BMI with tail1.65.512.3-3.23.5-2.7-3.1-3.0-2.82.62.8-2.82.8-2.82.8-2.11.91.9-1.9-2.31.91.9-0.60.3-0.20.90.7
BMI without tail0.30.93.6-1.51.9-0.7-1.0-1.1-1.10.90.9-0.90.9-0.90.9-0.61.30.6-0.7-0.90.80.80.30.70.40.80.5
Body weight1.15.014.8-3.43.8-2.0-2.5-2.8-2.32.42.5-2.52.5-2.52.5-1.52.91.3-1.4-2.41.81.80.31.30.61.61.1
Weight adjusted by age0.10.20.70.6-0.50.10.30.60.3-0.6-0.20.2-0.20.2-0.2-0.1-0.90.2-0.20.6-0.6-0.6-0.3-0.5-0.4-0.5-0.6
Bone surface0.50.83.0-0.5-0.20.61.50.91.7-0.6-1.41.4-1.41.4-1.4-0.20.80.2-0.21.0-0.6-0.6-0.30.2-0.3-0.4-1.0
Bone volume0.20.41.8-1.10.50.10.90.21.20.1-0.70.7-0.70.7-0.7-0.61.30.4-0.50.50.10.1-0.30.3-0.2-0.1-0.8
Breakpoint value in progressive ratio session2.02.49.7-3.13.1-1.3-1.4-1.7-1.41.41.5-1.51.5-1.51.5-1.52.11.4-1.5-1.21.31.3-0.00.90.20.90.2
Number of licking bursts0.20.30.8-0.10.60.80.50.40.6-0.9-0.50.5-0.50.5-0.50.40.8-0.20.00.2-0.0-0.00.90.90.70.60.1
Context. condit. distance diff. score2.73.36.2-2.22.3-1.8-2.1-2.5-2.12.52.1-2.12.1-2.12.1-1.12.00.7-0.6-2.12.02.0-0.10.60.31.11.0
Locomotion velocity, session 10.10.10.30.5-0.10.30.2-0.00.1-0.40.0-0.00.0-0.00.00.50.0-0.50.5-0.30.50.50.50.40.50.40.5
Locomotion distance, session 10.40.51.40.50.21.00.70.30.6-0.7-0.50.5-0.50.5-0.51.00.8-0.80.7-0.10.50.51.21.21.01.00.7
Locomotion velocity, session 20.70.81.61.3-1.11.21.31.01.2-0.7-1.11.1-1.11.1-1.11.0-0.4-0.90.90.6-0.3-0.30.60.30.40.10.0
Locomotion distance, session 20.91.33.00.70.21.71.30.81.2-1.2-1.11.1-1.11.1-1.11.51.0-1.21.00.20.40.41.71.71.51.20.8
Locomotion velocity, session 30.91.01.91.0-1.30.31.01.21.2-0.5-0.90.9-0.90.9-0.9-0.2-1.20.4-0.41.4-1.2-1.2-0.8-1.1-1.0-1.2-1.2
Locomotion distance, session 30.80.81.70.5-0.60.51.11.11.3-0.8-1.21.2-1.21.2-1.2-0.2-0.20.3-0.41.3-1.2-1.2-0.4-0.5-0.6-0.8-1.2
Stereotopy head waving bouts, day 30.81.03.01.6-1.01.30.70.60.7-1.2-0.50.5-0.50.5-0.51.7-0.3-1.61.6-0.10.20.21.40.91.20.81.1
Stereotopy head waving duration, day 30.91.03.31.7-1.11.10.40.20.3-0.8-0.20.2-0.20.2-0.21.8-0.4-1.81.8-0.50.50.51.40.81.30.91.5
Locomotion velocity, session 70.60.71.60.2-0.60.31.20.91.3-0.2-1.01.0-1.01.0-1.0-0.3-0.40.3-0.41.1-0.9-0.9-0.6-0.5-0.7-0.9-1.1
Locomotion distance, session 70.60.72.1-1.20.5-0.80.00.00.10.9-0.20.2-0.20.2-0.2-1.50.31.3-1.30.7-0.6-0.6-1.3-0.8-1.2-1.0-1.4
Stereotopy head waving bouts, day 71.31.53.21.8-1.71.51.71.31.7-1.5-1.51.5-1.51.5-1.51.3-0.5-1.31.30.9-0.5-0.50.70.20.5-0.0-0.0
Stereotopy head waving duration, day 71.41.73.51.9-1.61.71.61.01.6-1.4-1.41.4-1.41.4-1.41.80.0-1.81.80.40.00.01.20.81.10.60.6
Locomotion velocity, session 80.80.93.2-0.31.10.5-0.0-0.60.00.30.1-0.10.1-0.10.10.71.8-0.70.7-1.01.41.41.41.61.41.51.2
Locomotion distance, session 81.92.78.6-1.82.5-0.5-1.2-1.9-1.11.71.2-1.21.2-1.21.2-0.02.9-0.20.2-2.12.42.41.21.91.52.11.7
Degree of sensitization distance0.40.41.3-1.10.6-0.8-0.7-0.8-0.81.10.6-0.60.6-0.60.6-0.70.50.4-0.3-0.60.80.8-0.5-0.0-0.20.10.0
Degree of sensitization stereotypy0.30.40.90.9-0.90.60.90.60.9-0.7-0.70.7-0.70.7-0.70.6-0.3-0.60.60.5-0.3-0.30.2-0.00.1-0.1-0.1
Conditioned locomotion0.91.14.2-1.51.1-1.1-0.5-0.0-0.40.20.6-0.60.6-0.60.6-1.7-0.61.9-2.00.6-0.4-0.4-1.3-1.1-1.4-1.0-1.2
Cocaine response after cond. corrected2.53.06.41.8-0.92.52.01.41.9-1.8-2.02.0-2.02.0-2.02.31.1-2.11.90.60.00.02.21.91.91.30.8
Cocaine response after cond. not corrected3.84.58.52.7-2.02.92.62.32.5-2.7-2.72.7-2.72.7-2.72.5-0.0-2.12.01.5-1.0-1.01.91.21.40.50.2
Cocaine response before conditioning1.01.23.71.4-1.80.40.81.20.8-1.3-0.80.8-0.80.8-0.80.2-1.9-0.00.11.2-1.6-1.6-0.7-1.3-0.9-1.4-0.9
Saline control response3.54.710.01.4-2.10.61.82.71.8-1.9-2.12.1-2.12.1-2.1-0.7-2.71.2-1.33.2-2.7-2.7-1.8-2.3-2.3-2.8-3.0
Bone: connectivity density0.20.41.9-0.90.60.41.00.21.00.2-0.80.8-0.80.8-0.8-0.21.40.1-0.20.30.20.20.10.70.20.2-0.4
Bone: cortical apparent density0.00.10.30.5-0.50.20.40.20.3-0.2-0.10.1-0.10.1-0.10.3-0.2-0.40.40.1-0.1-0.10.1-0.10.1-0.00.0
Bone: cortical area0.10.10.3-0.10.20.30.3-0.00.4-0.4-0.00.0-0.00.0-0.00.30.2-0.30.3-0.20.50.50.40.40.40.40.4
Bone: cortical porosity0.30.31.80.9-1.20.40.2-0.00.20.1-0.30.3-0.30.3-0.30.9-0.1-1.21.3-0.30.40.40.30.10.50.30.6
Bone: cortical porosity0.30.31.00.4-0.6-0.1-0.3-0.6-0.30.60.3-0.30.3-0.30.30.50.1-0.81.0-0.70.80.80.20.10.40.50.8
Bone: cortical thickness0.20.31.10.6-0.60.50.5-0.00.4-0.4-0.10.1-0.10.1-0.10.90.0-1.01.0-0.40.80.80.60.50.70.60.8
Bone: cortical thickness0.30.41.80.5-1.00.00.60.70.6-0.7-0.30.3-0.30.3-0.3-0.1-1.40.2-0.10.7-0.7-0.7-0.7-0.9-0.7-0.9-0.6
Bone: cortical tissue density0.00.00.20.4-0.50.20.40.10.3-0.2-0.10.1-0.10.1-0.10.3-0.1-0.30.40.0-0.1-0.10.1-0.10.10.00.1
Condit. Reinf. active minus inactive responses3.13.46.51.9-2.51.32.12.32.1-2.2-2.12.1-2.12.1-2.10.5-1.8-0.30.32.3-2.4-2.4-0.6-1.2-0.9-1.7-1.7
Condit. Reinf. active-inactive response ratio3.84.18.12.5-2.91.82.32.62.3-2.5-2.42.4-2.42.4-2.41.1-1.9-0.80.82.3-2.4-2.4-0.1-0.9-0.5-1.5-1.4
Condit. Reinf. active responses1.21.53.00.9-1.60.21.11.41.1-1.3-1.01.0-1.01.0-1.0-0.3-1.70.4-0.31.6-1.6-1.6-1.1-1.4-1.2-1.6-1.5
Condit. Reinf. inactive responses0.60.72.0-1.41.3-1.1-0.7-0.8-0.70.70.9-0.90.9-0.90.9-1.20.31.2-1.2-0.40.70.7-0.7-0.3-0.6-0.1-0.3
Incentive salience index mean2.43.06.12.1-2.51.62.22.12.1-2.2-2.12.1-2.12.1-2.11.0-1.2-1.01.01.8-1.9-1.90.0-0.5-0.3-1.0-1.0
Condit. Reinf. lever presses0.81.22.71.7-1.41.31.20.91.2-1.2-1.21.2-1.21.2-1.21.4-0.1-1.51.50.4-0.4-0.41.00.60.80.30.4
Condit. Reinf. active minus inactive responses1.01.33.01.3-1.71.31.41.31.5-1.0-1.61.6-1.61.6-1.61.0-0.4-1.11.11.0-0.7-0.70.30.10.2-0.3-0.4
Condit. Reinf. active-inactive response ratio0.40.41.50.7-0.70.80.40.10.5-0.1-0.60.6-0.60.6-0.61.00.4-1.21.2-0.20.20.20.70.70.80.60.6
Condit. Reinf. active responses0.81.22.71.1-1.60.91.21.31.3-1.3-1.41.4-1.41.4-1.40.5-1.0-0.50.51.3-1.0-1.0-0.2-0.5-0.4-0.8-0.8
Condit. Reinf. inactive responses1.21.63.60.3-0.7-0.00.91.30.8-1.3-0.90.9-0.90.9-0.9-0.9-1.51.2-1.21.8-1.7-1.7-1.3-1.5-1.6-1.7-1.9
Condit. Reinf. lever presses0.10.20.60.3-0.10.50.70.60.7-0.5-0.60.6-0.60.6-0.60.2-0.10.0-0.10.6-0.4-0.40.20.1-0.0-0.0-0.3
Condit. Reinf. lever reinforcers received1.21.63.11.3-1.71.21.61.61.6-1.5-1.81.8-1.81.8-1.80.7-0.8-0.70.71.4-1.0-1.0-0.0-0.3-0.2-0.7-0.8
Conditioned reinforcement - actives1.32.35.7-1.30.9-2.4-1.8-1.3-1.71.31.5-1.51.5-1.51.5-2.2-1.12.0-1.9-0.50.10.1-2.1-1.8-1.8-1.1-1.0
Conditioned reinforcement - inactives0.10.21.2-0.80.6-0.4-0.1-0.4-0.00.1-0.10.1-0.10.1-0.1-0.71.10.4-0.4-0.10.30.3-0.40.1-0.20.0-0.5
Conditioned locomotion0.10.10.5-0.50.4-0.4-0.1-0.2-0.10.5-0.00.0-0.00.0-0.0-0.70.60.5-0.50.10.10.1-0.5-0.2-0.4-0.2-0.6
Patch foraging indifference point 0 sec0.10.20.7-0.80.1-0.5-0.3-0.1-0.3-0.20.1-0.10.1-0.10.1-0.7-0.40.7-0.60.2-0.1-0.1-0.8-0.6-0.7-0.6-0.6
Patch foraging indifference point AUC0.91.33.51.9-1.61.01.11.51.0-1.6-0.90.9-0.90.9-0.90.9-1.4-0.50.51.2-1.8-1.80.3-0.5-0.1-0.6-0.5
Delay disc. indifference point, 0s delay0.91.02.8-0.3-0.2-1.2-0.4-0.0-0.50.40.6-0.60.6-0.60.6-1.3-1.51.4-1.30.5-0.9-0.9-1.6-1.7-1.6-1.4-1.1
Delay disc. indifference point, 16s delay0.00.00.10.1-0.3-0.1-0.1-0.0-0.00.20.0-0.00.0-0.00.00.0-0.3-0.10.2-0.0-0.1-0.1-0.2-0.2-0.1-0.20.0
Delay disc. indifference point, 2s delay0.60.71.5-1.00.8-1.2-0.9-0.6-0.90.90.8-0.80.8-0.80.8-1.2-0.31.2-1.2-0.20.40.4-1.0-0.8-1.0-0.5-0.5
Delay disc. indifference point, 24s delay0.50.61.31.0-0.61.20.91.00.9-0.7-1.01.0-1.01.0-1.00.90.0-0.70.60.6-0.7-0.70.80.50.50.10.1
Delay disc. indifference point, 4s delay0.10.10.50.1-0.1-0.2-0.10.2-0.10.20.1-0.10.1-0.10.1-0.3-0.70.5-0.50.3-0.7-0.7-0.4-0.6-0.5-0.5-0.4
Delay disc. indifference point, 8s delay0.20.20.40.4-0.10.60.70.70.7-0.5-0.50.5-0.50.5-0.50.30.0-0.1-0.00.6-0.7-0.70.30.20.1-0.0-0.2
Indifference point function ln k1.32.35.0-2.02.1-1.1-1.7-2.0-1.61.61.5-1.51.5-1.51.5-0.62.00.2-0.2-1.92.22.20.41.10.81.31.2
Indifference point function log k1.32.35.0-2.02.1-1.1-1.7-2.0-1.61.61.5-1.51.5-1.51.5-0.62.00.2-0.2-1.92.22.20.41.10.81.31.2
Patch foraging total patch changes 0 sec0.10.20.8-0.90.3-0.7-0.6-0.4-0.60.00.4-0.40.4-0.40.4-0.7-0.20.6-0.6-0.10.10.1-0.7-0.5-0.6-0.4-0.4
Patch foraging total patch changes 12 sec0.50.62.00.8-1.20.70.81.10.7-1.4-0.80.8-0.80.8-0.80.4-1.0-0.30.31.0-0.8-0.8-0.2-0.4-0.3-0.6-0.6
Patch foraging total patch changes 18 sec0.91.33.41.2-1.50.71.01.50.9-1.6-1.01.0-1.01.0-1.00.3-1.50.0-0.11.5-1.8-1.8-0.4-1.0-0.7-1.3-1.1
Patch foraging total patch changes 24 sec0.71.24.30.6-1.2-0.6-0.20.7-0.2-0.5-0.10.1-0.10.1-0.1-0.8-2.10.9-0.81.0-1.6-1.6-1.5-1.9-1.6-1.7-1.3
Patch foraging total patch changes 6 sec0.30.41.1-1.10.6-0.9-0.6-0.5-0.70.40.7-0.70.7-0.70.7-0.90.10.8-0.8-0.20.00.0-0.7-0.5-0.6-0.3-0.4
Patch foraging time to switch 0 sec0.30.51.7-1.30.9-0.9-0.7-0.7-0.71.30.6-0.60.6-0.60.6-1.00.50.8-0.8-0.40.70.7-0.7-0.2-0.5-0.1-0.1
Patch foraging water rate 0 sec0.20.42.01.3-1.20.50.3-0.00.2-0.4-0.20.2-0.20.2-0.21.0-0.3-1.31.4-0.40.20.20.50.20.60.40.6
Patch foraging water rate 12 sec0.10.10.7-0.20.60.1-0.3-0.3-0.4-0.40.1-0.10.1-0.10.10.10.9-0.10.1-0.30.30.30.50.60.50.60.2
Patch foraging water rate 18 sec0.20.30.8-0.2-0.2-0.8-0.7-0.8-0.90.40.9-0.90.9-0.90.9-0.3-0.40.00.1-0.70.20.2-0.4-0.4-0.2-0.10.3
Patch foraging water rate 24 sec0.10.10.40.5-0.10.4-0.0-0.0-0.1-0.2-0.10.1-0.10.1-0.10.50.5-0.60.7-0.20.10.10.60.50.60.50.4
Patch foraging water rate 6 sec0.20.30.70.3-0.10.70.20.10.1-0.3-0.30.3-0.30.3-0.30.70.7-0.90.8-0.20.20.20.90.90.80.70.5
Seeking ratio, delayed vs. immediate footshock1.01.32.9-0.91.5-1.3-1.7-1.4-1.61.11.4-1.41.4-1.41.4-0.8-0.10.9-0.9-1.20.90.9-0.2-0.1-0.10.40.6
Distance traveled before self-admin0.60.81.61.0-0.91.31.11.01.0-1.0-1.21.2-1.21.2-1.21.0-0.1-0.90.90.60.10.10.60.50.50.10.1
Distance traveled after self-admin0.70.93.81.1-1.4-0.20.40.70.4-0.4-0.50.5-0.50.5-0.5-0.3-1.90.4-0.40.9-1.3-1.3-1.1-1.5-1.2-1.4-1.0
Extensor digitorum longus weight4.919.335.3-5.15.6-4.9-5.9-5.6-5.95.75.6-5.65.6-5.65.6-3.32.52.8-2.7-4.63.73.7-1.00.3-0.21.82.0
Bone: elastic displacement1.01.12.7-0.5-0.0-0.60.20.70.1-0.1-0.20.2-0.20.2-0.2-1.3-1.41.6-1.61.2-1.5-1.5-1.4-1.4-1.6-1.5-1.6
Bone: elastic work0.30.41.6-1.21.2-0.6-0.3-0.2-0.20.50.4-0.40.4-0.40.4-0.90.11.2-1.30.1-0.1-0.1-0.4-0.2-0.5-0.2-0.4
Bone: endosteal estimation0.10.31.1-1.00.9-0.7-0.5-0.4-0.20.50.5-0.50.5-0.50.5-0.90.40.9-0.9-0.10.10.1-0.5-0.2-0.5-0.3-0.4
Bone: endosteal perimeter0.20.51.8-0.60.6-0.10.40.70.6-0.5-0.30.3-0.30.3-0.3-0.8-0.31.2-1.30.9-0.8-0.8-0.5-0.4-0.8-0.8-1.1
Epididymis fat weight0.20.82.9-1.51.4-0.9-0.6-0.3-0.61.10.5-0.50.5-0.50.5-1.40.21.6-1.70.2-0.4-0.4-0.8-0.4-0.8-0.5-0.9
Delta time in closed arm before/after self-admin1.00.93.7-0.30.20.40.1-0.7-0.10.20.0-0.00.0-0.00.00.71.5-1.11.2-1.11.91.90.91.21.21.31.2
Delta time in open arm before/after self-admin0.10.10.50.40.20.3-0.30.1-0.4-0.50.3-0.30.3-0.30.30.60.2-0.30.3-0.2-0.1-0.10.70.40.60.40.6
Diff in mean of infusions in LGA sessions0.40.52.4-1.61.3-0.6-0.3-0.1-0.40.20.2-0.20.2-0.20.2-1.20.41.4-1.50.4-0.0-0.0-0.7-0.3-0.7-0.5-0.9
Delay discount exponential model param0.10.10.5-0.20.2-0.1-0.2-0.4-0.20.00.2-0.20.2-0.20.20.10.4-0.30.3-0.50.70.70.20.30.30.40.4
Extinction: sum of active levers before priming0.20.31.0-1.00.5-0.5-0.1-0.2-0.00.00.0-0.00.0-0.00.0-0.8-0.10.7-0.70.10.80.8-0.7-0.3-0.6-0.3-0.6
Active lever presses in extinction session 62.12.14.1-2.01.9-1.3-1.6-2.0-1.61.91.5-1.51.5-1.51.5-0.81.60.3-0.2-1.82.02.00.10.80.51.11.0
Bone: final force0.30.51.2-0.50.3-0.7-0.8-1.1-0.61.00.9-0.90.9-0.90.9-0.20.4-0.20.3-1.11.01.0-0.10.10.20.40.8
Bone: final moment0.30.51.2-0.70.3-0.8-0.8-1.1-0.61.00.9-0.90.9-0.90.9-0.40.30.10.0-1.00.90.9-0.3-0.1-0.00.30.5
Food consumed during 24 hour testing period0.20.31.40.20.10.10.20.60.2-0.8-0.20.2-0.20.2-0.2-0.3-0.50.6-0.70.7-1.2-1.2-0.2-0.4-0.4-0.5-0.7
Glucose1.32.05.3-2.32.3-1.7-1.5-1.5-1.61.61.5-1.51.5-1.51.5-1.71.21.6-1.7-0.90.90.9-0.7-0.1-0.50.1-0.2
Heart weight0.20.30.9-0.40.8-0.5-0.6-0.4-0.70.01.0-1.01.0-1.01.0-0.2-0.30.5-0.5-0.4-0.3-0.30.10.00.10.20.3
Delay discount hyperbolic model param0.10.10.40.00.00.20.0-0.20.1-0.2-0.00.0-0.00.0-0.00.30.5-0.50.5-0.30.60.60.40.40.40.40.4
Intermittent access intake day 1-15 change0.51.02.3-0.70.8-1.2-1.4-1.5-1.40.71.4-1.41.4-1.41.4-0.5-0.10.2-0.1-1.41.11.1-0.2-0.00.10.50.8
Intermittent access intake escalation0.71.42.9-1.21.0-1.5-1.6-1.7-1.61.11.5-1.51.5-1.51.5-0.8-0.10.5-0.4-1.51.31.3-0.5-0.2-0.10.40.7
Intermittent access intake escalation 22.22.54.7-1.31.8-1.1-2.0-2.1-2.01.41.9-1.91.9-1.91.9-0.31.4-0.00.1-2.21.91.90.61.00.91.61.6
Intermitt. access day 1 inactive lever presses0.51.74.42.1-1.61.71.31.51.4-1.4-1.61.6-1.61.6-1.61.40.1-1.31.31.1-1.3-1.30.90.40.6-0.0-0.3
Intermitt. access day 15 inactive lever presses0.40.91.51.2-1.01.21.11.01.1-1.1-1.21.2-1.21.2-1.21.00.4-1.01.00.7-0.7-0.70.70.50.50.2-0.0
Intermitt. access escalation Index0.20.20.80.5-0.30.60.50.90.6-0.9-0.40.4-0.40.4-0.40.4-0.50.0-0.10.7-0.7-0.70.2-0.0-0.0-0.3-0.2
Intermittent access day 1 total infusions0.30.41.2-1.10.8-0.9-0.6-0.6-0.50.80.5-0.50.5-0.50.5-1.10.50.9-0.9-0.20.30.3-0.7-0.4-0.6-0.3-0.5
Intermittent access day 15 total infusions2.13.27.2-2.11.6-2.7-2.2-1.9-2.11.62.0-2.02.0-2.02.0-2.4-0.72.2-2.1-1.00.70.7-2.0-1.4-1.6-0.7-0.6
Intermittent access terminal intake (last 3 days)3.04.07.9-2.42.3-2.8-2.7-2.4-2.62.02.4-2.42.4-2.42.4-2.40.12.1-2.0-1.61.21.2-1.5-0.9-1.1-0.1-0.1
Intermittent access total infusions2.53.06.5-2.31.8-2.6-2.0-1.7-1.91.61.8-1.81.8-1.81.8-2.5-0.32.3-2.3-0.70.70.7-1.9-1.4-1.6-0.8-0.9
Intermittent access day 1 locomotion1.11.43.2-1.81.8-1.5-1.2-1.3-1.31.41.3-1.31.3-1.31.3-1.50.81.4-1.4-0.80.70.7-0.7-0.2-0.60.1-0.3
Intermittent access day 15 total locomotion1.62.95.4-1.81.9-2.3-2.3-2.3-2.12.02.1-2.12.1-2.12.1-1.80.41.4-1.3-1.71.51.5-1.0-0.5-0.60.30.3
Intermittent access total locomotion2.32.76.1-2.11.8-2.5-1.9-1.9-1.81.91.8-1.81.8-1.81.8-2.30.22.0-1.9-1.11.11.1-1.6-1.0-1.3-0.3-0.5
Intermittent access standard deviation0.10.10.4-0.0-0.2-0.4-0.2-0.1-0.2-0.30.0-0.00.0-0.00.0-0.5-0.10.3-0.30.2-0.4-0.4-0.6-0.5-0.5-0.5-0.6
Left kidney weight0.52.25.41.4-0.42.21.10.91.1-1.6-1.31.3-1.31.3-1.32.21.4-2.01.80.1-0.1-0.12.32.12.01.41.1
Right kidney weight0.62.96.41.5-0.82.52.01.72.0-2.2-2.02.0-2.02.0-2.02.01.1-1.71.61.0-1.1-1.12.01.81.60.80.3
Cocaine induced anxiety0.50.73.41.8-1.60.60.80.91.2-0.7-0.40.4-0.40.4-0.40.8-1.2-0.60.70.6-1.1-1.10.1-0.5-0.1-0.4-0.1
Post-drug Anxiety2.52.67.32.7-2.22.12.11.92.4-1.9-1.71.7-1.71.7-1.71.9-0.5-1.71.61.3-1.1-1.11.10.30.7-0.10.0
Baseline Anxiety1.01.22.70.3-0.31.11.41.61.2-1.6-1.61.6-1.61.6-1.60.10.10.3-0.41.6-0.8-0.80.00.0-0.3-0.7-1.2
Tail length0.10.61.50.10.01.20.90.70.9-0.8-0.80.8-0.80.8-0.81.00.6-0.80.70.3-0.2-0.21.11.11.00.60.4
Length with tail0.10.63.3-1.61.8-0.1-0.3-0.6-0.20.60.5-0.50.5-0.50.5-0.31.80.3-0.5-0.50.40.40.61.20.70.90.4
Length without tail0.51.74.4-2.02.1-1.7-1.3-1.2-1.31.21.4-1.41.4-1.41.4-1.81.01.9-1.9-0.50.00.0-0.9-0.4-0.8-0.2-0.6
Times rat made contact with spout0.20.20.9-0.00.40.50.30.10.3-0.4-0.30.3-0.30.3-0.30.41.0-0.30.3-0.10.30.30.70.80.60.60.3
Lifetime Intake1.92.35.7-2.11.6-2.3-1.6-1.4-1.51.41.4-1.41.4-1.41.4-2.4-0.12.2-2.1-0.50.50.5-1.8-1.2-1.5-0.7-1.0
Liver weight, left0.20.31.4-0.30.80.50.0-0.00.1-0.4-0.20.2-0.20.2-0.20.31.2-0.20.1-0.20.30.30.91.00.80.80.4
Liver weight, right0.50.84.3-0.31.10.4-0.1-0.60.1-0.10.2-0.20.2-0.20.20.72.1-0.70.7-0.91.01.01.41.61.41.51.0
Locomotor activity0.81.33.40.4-0.41.51.81.21.7-1.3-1.61.6-1.61.6-1.60.90.7-0.70.60.9-0.7-0.70.90.90.70.2-0.2
Locomotor testing distance0.71.22.80.7-0.81.51.70.91.5-1.1-1.51.5-1.51.5-1.51.11.0-1.21.20.50.00.00.91.00.90.50.1
Locomotor testing rearing1.93.97.41.7-2.21.42.42.62.2-2.3-2.52.5-2.52.5-2.50.2-1.50.1-0.22.7-2.4-2.4-0.7-1.1-1.1-1.9-2.1
Locomotion in novel chamber0.20.31.1-0.30.90.4-0.2-0.2-0.20.50.1-0.10.1-0.10.10.50.8-0.30.2-0.40.10.11.01.11.00.80.7
Locomotion in novel chamber post-restriction0.91.54.01.1-0.41.40.60.00.4-0.3-0.40.4-0.40.4-0.41.91.5-2.02.0-0.70.70.72.01.82.01.61.7
Fecal boli incidents, locomotor time 10.20.30.90.50.21.00.60.70.6-0.9-0.60.6-0.60.6-0.60.60.5-0.40.20.4-0.2-0.20.80.70.60.40.1
Change in fecal boli incidents, locomotor task0.80.82.5-0.1-0.3-0.8-0.30.3-0.20.30.3-0.30.3-0.30.3-1.0-1.41.1-1.10.7-1.6-1.6-1.2-1.4-1.3-1.2-1.1
Time >=10cm from walls, locomotor time 12.62.85.22.2-2.22.01.72.21.6-2.3-1.81.8-1.81.8-1.81.7-1.8-1.31.21.6-1.9-1.90.7-0.10.3-0.6-0.3
Bouts of movement, locomotor time 10.20.30.9-0.90.3-0.8-0.2-0.4-0.40.80.2-0.20.2-0.20.2-0.90.20.7-0.6-0.10.20.2-0.9-0.5-0.7-0.4-0.5
Total resting periods, locomotor time 10.60.62.1-1.50.8-1.2-0.7-0.9-0.91.30.6-0.60.6-0.60.6-1.20.50.9-0.9-0.40.40.4-0.9-0.4-0.7-0.3-0.4
Rest time, locomotor task time 13.64.511.0-3.33.3-2.2-2.5-2.7-2.52.42.6-2.62.6-2.62.6-1.51.51.4-1.4-2.31.71.7-0.20.70.31.21.1
Distance moved, locomotor task time 13.75.615.73.1-4.02.22.92.93.0-2.6-2.92.9-2.92.9-2.91.6-1.8-1.61.72.5-1.7-1.7-0.2-0.9-0.5-1.5-1.3
Vertical activity count, locomotor time 11.12.58.42.3-2.91.11.82.01.8-1.7-1.71.7-1.71.7-1.70.7-1.8-0.70.81.8-1.3-1.3-0.6-1.3-0.8-1.4-1.2
Time >=10cm from walls, locomotor time 20.91.33.51.4-1.11.51.31.51.5-1.9-1.21.2-1.21.2-1.21.1-0.9-0.70.61.1-1.3-1.30.70.20.3-0.2-0.2
Bouts of movement, locomotor time 20.30.40.80.8-0.50.90.90.70.6-0.7-0.90.9-0.90.9-0.90.70.1-0.50.50.5-0.7-0.70.50.30.40.0-0.0
Total resting periods, locomotor time 20.30.51.01.0-0.61.00.90.80.7-0.8-1.01.0-1.01.0-1.00.80.1-0.70.60.5-0.7-0.70.70.40.50.10.1
Rest time, locomotor task time 20.60.82.1-1.21.5-1.0-1.1-1.1-1.11.21.1-1.11.1-1.11.1-0.60.40.7-0.7-1.00.60.6-0.00.20.10.50.5
Distance moved, locomotor task time 21.21.44.81.4-2.21.11.61.41.6-1.5-1.51.5-1.51.5-1.50.8-0.7-1.01.01.2-0.3-0.3-0.2-0.5-0.3-0.8-0.7
Vertical activity count, locomotor time 20.20.31.50.1-0.30.50.3-0.10.3-0.4-0.20.2-0.20.2-0.20.50.9-0.80.9-0.31.21.20.50.60.60.60.4
Light reinforcement 10.20.51.70.6-0.80.91.00.90.8-1.3-0.90.9-0.90.9-0.90.6-0.0-0.60.60.7-0.3-0.30.30.30.2-0.1-0.2
Light reinforcement 20.20.30.8-0.5-0.2-0.40.00.2-0.1-0.10.1-0.10.1-0.10.1-0.6-0.90.7-0.70.6-0.9-0.9-0.9-0.8-0.9-0.8-0.7
Bone: marrow area0.10.30.9-1.00.8-0.7-0.5-0.4-0.20.40.4-0.40.4-0.40.4-0.90.30.9-0.9-0.10.00.0-0.5-0.3-0.5-0.3-0.4
Bone: maximum diameter0.20.41.40.20.31.00.80.80.9-1.2-0.70.7-0.70.7-0.70.50.3-0.20.10.5-0.2-0.20.80.70.50.2-0.0
Bone: maximum force0.61.02.1-1.31.0-1.1-1.0-1.4-0.91.41.2-1.21.2-1.21.2-0.70.70.4-0.3-1.21.31.3-0.40.0-0.10.40.6
Bone: maximum moment0.51.02.0-1.41.0-1.2-1.0-1.3-0.81.41.2-1.21.2-1.21.2-0.90.70.6-0.5-1.11.21.2-0.6-0.1-0.20.20.4
Mean time between licks in bursts0.20.41.9-1.31.4-0.2-0.3-0.5-0.20.30.3-0.30.3-0.30.3-0.41.30.4-0.5-0.30.70.70.30.70.30.60.1
Mean num. licks in bursts0.00.10.60.4-0.8-0.1-0.1-0.1-0.20.30.1-0.10.1-0.10.10.1-0.3-0.30.5-0.10.10.1-0.3-0.4-0.1-0.20.1
Cd content in liver0.30.30.80.30.00.2-0.3-0.5-0.2-0.10.3-0.30.3-0.30.30.60.5-0.70.8-0.80.70.70.70.60.80.80.9
Co content in liver0.80.92.7-1.31.6-0.8-0.9-1.2-0.81.01.1-1.11.1-1.11.1-0.61.30.5-0.6-1.01.11.10.20.60.30.70.5
Cu content in liver0.70.81.8-1.30.6-1.3-0.9-1.0-0.91.30.9-0.90.9-0.90.9-1.20.30.9-0.7-0.60.60.6-1.1-0.6-0.7-0.4-0.3
Fe content in liver1.31.63.9-1.40.8-1.7-1.7-1.8-1.72.01.7-1.71.7-1.71.7-1.00.30.6-0.4-1.41.01.0-0.8-0.4-0.30.10.5
K content in liver1.21.22.61.0-0.41.61.00.71.1-1.1-1.11.1-1.11.1-1.11.50.8-1.41.30.10.20.21.61.41.41.00.8
Mg content in liver0.20.20.50.7-0.70.50.50.40.4-0.7-0.50.5-0.50.5-0.50.5-0.2-0.50.50.3-0.1-0.10.20.00.2-0.10.0
Mn content in liver0.20.20.5-0.4-0.10.40.70.30.7-0.2-0.60.6-0.60.6-0.60.00.7-0.20.20.3-0.2-0.20.00.30.1-0.0-0.3
Na content in liver0.70.81.51.0-1.20.80.91.11.0-1.0-1.01.0-1.01.0-1.00.5-1.1-0.40.31.0-1.2-1.20.0-0.4-0.2-0.6-0.5
Rb content in liver0.20.20.5-0.1-0.50.10.60.30.5-0.3-0.60.6-0.60.6-0.6-0.20.30.00.00.5-0.2-0.2-0.4-0.3-0.4-0.5-0.7
Se content in liver1.11.33.4-1.20.6-1.5-1.3-1.7-1.31.91.5-1.51.5-1.51.5-0.80.70.2-0.0-1.51.21.2-0.6-0.2-0.10.30.6
Sr content in liver0.70.61.51.0-0.21.20.80.70.7-1.0-0.60.6-0.60.6-0.61.20.1-0.80.70.20.00.01.20.90.90.70.6
Zn content in liver0.40.41.40.10.30.4-0.0-0.4-0.00.10.1-0.10.1-0.10.10.61.2-0.70.7-0.61.01.00.80.90.90.90.9
Bone: minimum diameter0.71.22.1-1.31.2-1.4-1.4-1.3-1.21.21.4-1.41.4-1.41.4-1.00.30.9-0.8-1.11.01.0-0.6-0.3-0.30.10.4
Time in familiar zone, hab. session 10.10.10.30.2-0.40.30.40.10.40.1-0.40.4-0.40.4-0.40.30.5-0.50.50.00.00.00.10.20.20.10.1
Time in novel zone, hab. session 10.10.10.60.5-0.2-0.0-0.20.0-0.2-0.30.2-0.20.2-0.20.20.1-0.8-0.00.1-0.0-0.1-0.10.1-0.2-0.0-0.00.1
Total zone transitions, hab. session 10.60.92.10.6-0.30.81.21.41.1-1.5-1.11.1-1.11.1-1.10.2-0.50.3-0.51.4-1.4-1.40.1-0.2-0.3-0.6-0.9
Total locomotion distance, hab. session 10.20.31.20.1-0.10.10.30.60.3-0.5-0.30.3-0.30.3-0.3-0.2-0.90.6-0.60.7-1.1-1.1-0.3-0.5-0.5-0.6-0.6
Locomotion velocity, hab. session 10.20.20.90.2-0.10.30.30.70.3-0.7-0.40.4-0.40.4-0.40.0-0.70.3-0.40.6-0.9-0.9-0.0-0.2-0.3-0.4-0.4
Time in familiar zone, hab. session 20.10.10.3-0.50.40.1-0.3-0.3-0.30.50.1-0.10.1-0.10.10.20.4-0.20.2-0.40.50.50.30.50.40.40.4
Time in novel zone, hab. session 20.20.20.90.8-1.00.10.50.20.5-0.4-0.10.1-0.10.1-0.10.2-0.7-0.30.40.2-0.3-0.3-0.2-0.5-0.2-0.3-0.2
Total zone transitions, hab. session 20.81.12.40.40.31.51.51.11.4-1.4-1.41.4-1.41.4-1.40.81.0-0.40.20.8-0.3-0.31.11.10.80.6-0.1
Total locomotion distance, hab. session 21.01.32.80.9-0.41.61.71.31.6-1.3-1.61.6-1.61.6-1.61.00.5-0.70.61.0-0.4-0.41.00.90.70.4-0.1
Locomotion velocity, hab. session 20.91.22.40.8-0.31.51.51.31.5-1.3-1.51.5-1.51.5-1.50.90.4-0.50.41.0-0.5-0.50.90.80.50.3-0.3
Novel to familiar place preference ratio0.00.00.10.2-0.3-0.1-0.1-0.1-0.2-0.20.1-0.10.1-0.10.10.1-0.2-0.20.2-0.1-0.2-0.2-0.1-0.2-0.0-0.10.1
Novelty place preference0.10.10.40.3-0.3-0.1-0.3-0.4-0.40.00.4-0.40.4-0.40.40.4-0.0-0.50.6-0.50.20.20.20.10.30.30.6
Time in novel zone, NPP test0.10.10.30.1-0.3-0.3-0.5-0.4-0.50.10.5-0.50.5-0.50.50.1-0.2-0.30.4-0.50.10.1-0.1-0.20.10.10.4
Total zone transitions, NPP test0.60.91.70.5-0.21.31.00.40.8-0.9-0.90.9-0.90.9-0.91.21.0-1.31.2-0.10.50.51.31.31.21.00.8
Total locomotion distance, NPP test0.10.20.6-0.20.30.40.2-0.10.0-0.1-0.20.2-0.20.2-0.20.40.7-0.50.4-0.30.50.50.60.80.70.70.5
Locomotion velocity, NPP test0.30.41.3-0.00.30.80.40.00.3-0.3-0.40.4-0.40.4-0.40.81.0-0.80.8-0.30.60.61.01.21.00.90.7
Intraocular pressure0.10.10.4-0.60.7-0.1-0.10.1-0.30.2-0.10.1-0.10.1-0.1-0.40.20.5-0.60.2-0.5-0.5-0.10.1-0.1-0.1-0.3
Delta distance traveled before/after self-admin2.93.19.0-0.3-0.4-2.3-0.9-0.3-1.00.61.0-1.01.0-1.01.0-2.3-2.62.3-2.20.6-1.6-1.6-2.7-3.0-2.7-2.4-1.9
Delta ambulatory time before/after self-admin1.41.74.5-0.4-0.1-1.8-0.8-0.4-0.90.80.9-0.90.9-0.90.9-1.8-1.51.8-1.70.3-1.1-1.1-2.0-2.1-2.0-1.6-1.4
Parametrial fat weight0.00.10.30.00.20.20.30.10.10.1-0.30.3-0.30.3-0.3-0.00.6-0.0-0.00.1-0.0-0.00.20.30.10.1-0.2
Pavlov. Cond. lever latency0.40.51.4-0.20.40.1-0.4-0.7-0.40.40.6-0.60.6-0.60.60.60.6-0.60.7-1.01.11.10.80.80.91.01.2
Pavlov. Cond. magazine entry latency0.81.12.10.9-0.71.41.30.91.4-0.7-1.41.4-1.41.4-1.41.10.9-1.11.10.6-0.1-0.11.01.00.80.50.1
Pavlov. Cond. change in total contacts0.20.20.50.3-0.60.20.30.40.4-0.1-0.50.5-0.50.5-0.5-0.0-0.1-0.10.10.5-0.7-0.7-0.2-0.3-0.3-0.4-0.5
Pavlov. Cond. index score0.20.30.70.2-0.30.40.60.60.7-0.2-0.80.8-0.80.8-0.8-0.00.3-0.0-0.00.6-0.5-0.5-0.1-0.0-0.2-0.3-0.6
Pavlov. Cond. latency score0.20.30.70.4-0.40.50.60.60.7-0.3-0.90.9-0.90.9-0.90.20.2-0.20.10.6-0.5-0.50.10.1-0.0-0.2-0.5
Pavlov. Cond. lever contacts0.20.20.60.1-0.3-0.20.30.30.3-0.0-0.40.4-0.40.4-0.4-0.5-0.30.5-0.50.6-0.7-0.7-0.6-0.6-0.6-0.7-0.8
Pavlov. Cond. magazine entry number0.50.71.4-0.70.8-1.0-1.1-0.7-1.10.41.2-1.21.2-1.21.2-0.7-0.60.9-0.9-0.50.30.3-0.5-0.5-0.5-0.20.1
Pavlov. Cond. intertrial magazine entries0.50.61.8-0.5-0.1-0.9-0.20.0-0.20.20.3-0.30.3-0.30.3-1.2-0.61.2-1.10.5-0.6-0.6-1.3-1.3-1.3-1.1-1.1
Pavlov. Cond. lever-magazine prob. diff.0.30.30.80.2-0.30.50.70.60.8-0.2-0.90.9-0.90.9-0.90.10.4-0.10.10.7-0.6-0.6-0.00.1-0.1-0.2-0.6
Pavlov. Cond. response bias0.50.61.40.7-0.80.91.00.81.1-0.5-1.21.2-1.21.2-1.20.60.4-0.70.70.6-0.4-0.40.40.40.30.0-0.3
Pavlov. Cond. lever latency0.10.10.40.3-0.6-0.3-0.2-0.2-0.20.00.2-0.20.2-0.20.2-0.0-0.5-0.20.3-0.1-0.3-0.3-0.3-0.4-0.2-0.3-0.0
Pavlov. Cond. magazine entry latency0.20.20.60.30.00.70.50.30.5-0.2-0.40.4-0.40.4-0.40.70.3-0.60.50.0-0.0-0.00.80.70.70.60.5
Pavlov. Cond. change in total contacts0.71.12.30.8-0.31.51.20.71.0-0.8-1.21.2-1.21.2-1.21.31.0-1.31.20.20.40.41.41.41.21.00.6
Pavlov. Cond. index score0.10.20.40.30.10.60.60.30.5-0.1-0.50.5-0.50.5-0.50.60.4-0.40.30.10.20.20.60.60.50.50.3
Pavlov. Cond. latency score0.20.30.90.40.10.80.50.20.5-0.2-0.40.4-0.40.4-0.40.80.6-0.70.6-0.10.40.40.90.90.80.80.6
Pavlov. Cond. lever contacts0.10.10.3-0.00.40.40.40.30.4-0.1-0.40.4-0.40.4-0.40.20.5-0.0-0.10.20.20.20.40.50.30.30.0
Pavlov. Cond. magazine entry number0.81.02.0-0.90.7-1.4-1.1-0.5-1.10.51.0-1.01.0-1.01.0-1.4-0.61.4-1.4-0.1-0.2-0.2-1.2-1.1-1.2-0.9-0.8
Pavlov. Cond. intertrial magazine entries0.40.52.10.6-1.1-0.10.50.70.6-0.7-0.40.4-0.40.4-0.4-0.3-1.50.2-0.20.8-0.8-0.8-0.9-1.1-0.9-1.1-0.9
Pavlov. Cond. lever-magazine prob. diff.0.20.30.60.4-0.10.70.70.40.7-0.3-0.60.6-0.60.6-0.60.70.3-0.50.50.20.10.10.60.60.50.50.3
Pavlov. Cond. response bias0.10.20.4-0.10.30.50.60.30.60.0-0.50.5-0.50.5-0.50.20.7-0.10.00.20.20.20.40.60.30.3-0.0
Time in closed arm before self-admin0.10.10.3-0.30.0-0.5-0.2-0.2-0.20.50.4-0.40.4-0.40.4-0.4-0.30.4-0.3-0.0-0.5-0.5-0.4-0.4-0.4-0.2-0.2
Time in closed arm after self-admin0.91.02.7-0.60.6-0.3-0.5-1.3-0.60.50.8-0.80.8-0.80.80.40.9-0.80.9-1.51.61.60.71.01.01.31.4
Time in open arm before self-admin0.20.31.2-1.00.9-0.4-0.2-0.5-0.30.90.1-0.10.1-0.10.1-0.61.10.4-0.4-0.30.80.8-0.20.3-0.00.2-0.2
Time in open arm after self-admin0.10.20.9-0.40.8-0.2-0.30.2-0.20.20.1-0.10.1-0.10.1-0.50.50.8-0.90.3-0.3-0.3-0.1-0.1-0.3-0.2-0.5
Bone: periosteal estimation0.00.10.5-0.70.6-0.3-0.1-0.20.20.00.2-0.20.2-0.20.2-0.40.30.5-0.5-0.10.30.3-0.20.0-0.2-0.1-0.1
Bone: periosteal perimeter0.40.71.60.5-0.40.71.11.21.3-1.2-1.01.0-1.01.0-1.00.1-0.70.3-0.41.2-0.8-0.8-0.1-0.3-0.4-0.6-0.8
Bone: post-yield work0.10.21.0-0.70.80.10.4-0.20.5-0.10.1-0.10.1-0.10.1-0.11.00.0-0.1-0.20.50.50.30.70.40.50.2
Progressive ratio test 1 active lever presses1.01.23.3-0.60.1-1.2-0.30.1-0.40.20.1-0.10.1-0.10.1-1.7-1.31.7-1.70.9-0.7-0.7-1.8-1.7-1.8-1.5-1.7
Progressive ratio test 1 breakpoint0.91.13.0-0.70.2-1.2-0.30.1-0.40.30.2-0.20.2-0.20.2-1.7-1.11.7-1.70.8-0.5-0.5-1.7-1.6-1.7-1.4-1.6
Progressive ratio test 1 inactive lever presses0.00.00.1-0.1-0.2-0.10.30.00.40.0-0.20.2-0.20.2-0.2-0.20.20.1-0.10.2-0.2-0.2-0.3-0.1-0.3-0.1-0.4
Progressive ratio test 2 active lever presses2.42.86.1-2.11.8-2.5-2.0-1.6-1.81.61.8-1.81.8-1.81.8-2.4-0.12.3-2.2-0.70.60.6-1.8-1.3-1.5-0.6-0.8
Progressive ratio test 2 breakpoint2.62.96.3-2.32.0-2.5-2.1-1.7-1.91.61.8-1.81.8-1.81.8-2.40.02.3-2.3-0.80.60.6-1.8-1.2-1.5-0.6-0.7
Progressive ratio test 2 inactive lever presses0.60.92.3-1.51.3-1.5-1.0-1.1-0.80.80.9-0.90.9-0.90.9-1.50.41.3-1.3-0.50.10.1-1.0-0.5-0.8-0.2-0.5
Incentive Sensitization - Responses1.92.75.5-2.32.3-2.2-2.1-1.9-1.81.81.9-1.91.9-1.91.9-2.00.71.8-1.8-1.20.80.8-1.1-0.4-0.80.1-0.1
Incentive Sensitization - Breakpoint2.33.06.0-2.52.4-2.3-2.3-2.1-2.01.92.1-2.12.1-2.12.1-2.00.71.9-1.8-1.40.90.9-1.0-0.4-0.70.20.0
Sum of active levers in priming session hrs 5-60.30.31.2-1.11.0-0.6-0.4-0.6-0.30.50.4-0.40.4-0.40.4-0.80.70.6-0.7-0.30.70.7-0.30.1-0.20.1-0.2
Progressive ratio0.40.63.0-1.11.7-0.4-0.6-0.7-0.70.60.9-0.90.9-0.90.9-0.40.80.7-0.8-0.60.20.20.40.60.30.70.4
Food seeking constrained by brief footshock1.82.25.4-2.32.1-1.9-1.4-1.2-1.52.01.3-1.31.3-1.31.3-2.20.42.3-2.3-0.40.20.2-1.4-0.7-1.3-0.4-0.9
Seeking ratio, punishment vs. effort0.20.21.1-0.2-0.6-0.7-0.4-0.4-0.30.70.1-0.10.1-0.10.1-0.6-0.50.3-0.1-0.10.30.3-1.0-0.9-0.8-0.6-0.4
Retroperitoneal fat weight0.00.10.3-0.20.1-0.40.0-0.20.10.60.2-0.20.2-0.20.2-0.5-0.40.4-0.40.1-0.1-0.1-0.5-0.4-0.4-0.3-0.3
Reaction time number correct0.30.61.3-1.10.8-1.0-0.8-0.7-1.00.90.9-0.90.9-0.90.9-1.00.20.9-0.9-0.40.10.1-0.7-0.5-0.6-0.3-0.3
Reaction time mean minus median0.30.73.11.5-1.80.10.20.70.2-0.3-0.50.5-0.50.5-0.50.2-1.7-0.20.30.7-1.0-1.0-0.7-1.2-0.8-1.1-0.6
Reaction time mean minus median AUC0.20.63.31.2-1.8-0.00.20.50.1-0.2-0.40.4-0.40.4-0.40.1-1.5-0.30.50.6-0.7-0.7-0.8-1.2-0.8-1.1-0.5
Reaction time num false alarms1.92.65.1-1.11.8-0.3-1.6-1.9-1.61.21.4-1.41.4-1.41.40.61.9-0.80.8-2.32.22.21.41.81.72.12.2
Reaction time num false alarms AUC1.52.34.7-0.91.60.1-1.1-1.6-1.10.81.1-1.11.1-1.11.10.82.1-1.01.0-2.02.22.21.62.01.92.12.1
Reaction time trials correct on left0.30.61.3-1.10.8-1.0-0.8-0.7-1.00.90.9-0.90.9-0.90.9-1.00.20.9-0.9-0.40.10.1-0.7-0.5-0.6-0.3-0.3
Reaction time trials on left0.30.51.1-1.00.7-0.9-0.7-0.6-0.90.80.8-0.80.8-0.80.8-0.90.20.8-0.8-0.30.10.1-0.7-0.4-0.5-0.3-0.3
Reaction time mean1.52.47.32.1-2.70.51.01.71.1-1.0-1.31.3-1.31.3-1.30.2-2.6-0.10.21.7-2.1-2.1-1.1-1.9-1.3-1.9-1.4
Reaction time mean AUC1.32.06.91.9-2.60.40.91.51.0-0.8-1.21.2-1.21.2-1.20.2-2.3-0.10.31.6-1.8-1.8-1.2-1.8-1.3-1.8-1.3
Median of all reaction times1.62.26.31.8-2.50.41.11.61.2-1.0-1.31.3-1.31.3-1.30.1-2.50.00.11.7-2.0-2.0-1.2-1.8-1.4-1.8-1.4
Reaction time omissions1.42.15.42.3-1.91.91.31.41.4-1.5-1.61.6-1.61.6-1.62.0-0.4-1.91.90.7-0.5-0.51.30.71.00.40.5
Reaction time false alarm rate1.11.64.00.10.60.7-0.4-0.8-0.30.00.3-0.30.3-0.30.31.41.4-1.51.5-1.51.81.81.81.91.91.92.0
Reaction time premature initiation rate0.40.52.01.4-1.10.80.40.80.5-1.4-0.50.5-0.50.5-0.50.9-1.0-0.70.70.5-0.8-0.80.4-0.10.2-0.20.2
Reaction time premature initiations0.20.31.41.0-0.80.50.20.70.1-1.2-0.30.3-0.30.3-0.30.5-0.9-0.30.20.5-1.0-1.00.1-0.3-0.0-0.4-0.1
Std. dev. reaction times0.81.46.62.5-2.61.00.81.10.8-0.7-1.21.2-1.21.2-1.21.3-1.5-1.31.50.7-1.0-1.00.1-0.60.0-0.6-0.0
Reaction time trials completed0.30.51.1-1.00.7-0.9-0.7-0.6-0.90.80.8-0.80.8-0.80.8-0.90.20.8-0.8-0.30.10.1-0.7-0.4-0.5-0.3-0.3
Reaction time trials AUC0.30.51.1-1.00.7-1.0-0.8-0.7-1.00.90.9-0.90.9-0.90.9-0.90.30.8-0.7-0.40.20.2-0.6-0.4-0.5-0.2-0.2
Run reversals in cocaine runway, females1.01.02.81.1-0.21.70.91.00.7-1.4-0.90.9-0.90.9-0.91.50.6-1.11.00.4-0.5-0.51.61.31.30.70.5
Run reversals in cocaine runway, males1.11.12.70.4-0.11.20.5-0.00.6-0.3-0.60.6-0.60.6-0.61.41.2-1.61.6-0.61.41.41.51.61.61.51.3
Latency to leave start box in cocaine runway2.22.65.32.3-2.21.81.92.11.9-2.2-1.91.9-1.91.9-1.91.4-1.2-1.11.01.6-1.6-1.60.5-0.20.1-0.7-0.6
Latency to leave start box in cocaine runway, F1.01.13.92.0-1.71.21.01.31.0-1.5-1.11.1-1.11.1-1.11.1-0.8-1.01.00.9-1.0-1.00.4-0.20.2-0.5-0.1
Latency to leave start box in cocaine runway, M1.91.83.31.1-1.50.81.51.71.5-1.5-1.51.5-1.51.5-1.50.2-1.60.1-0.21.8-1.7-1.7-0.5-0.9-0.8-1.2-1.3
Std. dev. time between licks in bursts0.81.13.00.00.50.90.2-0.50.2-0.1-0.10.1-0.10.1-0.11.21.5-1.31.3-1.01.51.51.51.71.61.71.4
Total sessions with >9 infusions0.80.92.8-0.4-0.0-0.9-0.00.30.2-0.1-0.10.1-0.10.1-0.1-1.5-0.71.5-1.40.9-1.1-1.1-1.5-1.4-1.6-1.3-1.7
Short access day 1 total inactive lever presses1.41.94.00.7-0.80.81.71.81.8-1.1-1.71.7-1.71.7-1.7-0.2-0.70.6-0.82.0-1.9-1.9-0.5-0.7-0.9-1.2-1.7
Short access day 10 total inactive lever presses1.22.85.92.3-1.72.41.71.51.8-1.7-1.71.7-1.71.7-1.72.30.9-2.32.30.7-0.8-0.81.81.41.50.70.6
Short access day 1 total infusions0.70.92.8-0.3-0.3-0.50.50.50.5-0.2-0.70.7-0.70.7-0.7-1.2-0.41.1-1.11.1-1.2-1.2-1.3-1.2-1.4-1.2-1.7
Short access day 10 total infusions1.21.63.7-1.21.0-1.9-1.6-1.4-1.71.31.5-1.51.5-1.51.5-1.6-0.51.4-1.3-0.90.60.6-1.2-1.0-1.0-0.4-0.2
Short access total infusions0.70.92.5-0.80.3-1.3-0.5-0.3-0.30.50.3-0.30.3-0.30.3-1.6-0.71.5-1.40.4-0.4-0.4-1.6-1.4-1.5-1.1-1.3
Short access day 1 locomotion1.41.74.4-2.01.7-1.9-1.3-1.4-1.31.31.2-1.21.2-1.21.2-2.10.41.9-1.8-0.60.40.4-1.4-0.8-1.2-0.4-0.8
Short access day 10 total locomotion0.00.10.30.5-0.3-0.20.00.1-0.3-0.2-0.00.0-0.00.0-0.0-0.2-0.30.1-0.10.1-0.2-0.2-0.3-0.4-0.3-0.3-0.3
Short access total locomotion1.11.33.70.0-0.6-1.00.20.40.2-0.2-0.20.2-0.20.2-0.2-1.5-1.61.5-1.41.1-1.2-1.2-1.9-1.9-1.9-1.7-1.8
One hour access (0.3 mA shock)3.84.410.8-2.11.4-3.3-2.7-2.3-2.52.12.3-2.32.3-2.32.3-2.7-1.22.3-2.1-1.31.01.0-2.4-2.0-2.0-0.8-0.6
Compulsive drug intake1.41.77.42.5-2.60.51.01.21.2-1.2-0.80.8-0.80.8-0.80.8-2.7-0.60.71.0-1.6-1.6-0.4-1.4-0.7-1.0-0.4
One hour access (shock baseline)3.04.610.0-3.22.6-2.9-2.7-2.4-2.62.22.3-2.32.3-2.32.3-2.80.52.4-2.3-1.41.71.7-1.8-0.9-1.3-0.2-0.4
Social response proportion1.72.04.61.5-1.21.31.62.11.5-2.1-1.61.6-1.61.6-1.60.5-1.60.0-0.22.0-1.7-1.7-0.0-0.6-0.5-1.2-1.2
Social responses1.21.63.31.7-1.31.81.61.21.3-1.6-1.41.4-1.41.4-1.41.7-0.0-1.61.50.6-0.1-0.11.30.91.10.50.5
Social time0.30.41.11.1-0.50.80.70.70.8-0.8-0.60.6-0.60.6-0.60.7-0.1-0.50.50.5-0.5-0.50.60.30.40.10.1
Soleus weight0.92.76.0-1.81.7-2.1-2.4-2.0-2.52.22.1-2.12.1-2.12.1-1.60.41.4-1.3-1.50.70.7-0.9-0.5-0.60.10.3
Bone: stiffness0.61.03.2-1.31.1-0.6-0.9-1.3-0.81.30.9-0.90.9-0.90.9-0.21.5-0.10.2-1.31.81.80.20.80.61.00.9
Tibialis anterior weight0.82.98.3-1.40.9-2.0-1.2-0.1-1.10.70.9-0.90.9-0.90.9-2.5-1.52.8-2.90.9-1.5-1.5-2.4-2.3-2.5-2.0-2.0
Time to tail flick, vehicle, before self-admin1.01.12.11.3-1.41.01.11.41.1-0.7-1.31.3-1.31.3-1.30.6-1.0-0.40.41.2-1.3-1.30.0-0.4-0.2-0.7-0.6
Time to tail flick, vehicle, after self-admin1.41.96.9-1.21.80.3-0.8-1.2-0.70.20.7-0.70.7-0.70.70.72.6-0.90.8-1.61.91.91.62.21.82.11.7
Time to tail flick, test, before self-admin0.20.20.9-0.20.2-0.5-0.1-0.50.00.90.3-0.30.3-0.30.3-0.4-0.00.2-0.1-0.40.80.8-0.4-0.2-0.20.0-0.0
Time to tail flick, test, after self-admin0.20.20.9-0.1-0.10.30.2-0.20.10.3-0.20.2-0.20.2-0.20.50.7-0.70.7-0.40.90.90.40.60.60.50.6
Delta time to tail flick, vehicle, before/after SA0.80.82.7-0.10.60.70.1-0.40.2-0.5-0.10.1-0.10.1-0.10.91.7-1.01.0-0.71.11.11.31.51.31.41.1
Delta time to tail flick, test, before/after SA0.40.40.70.3-0.60.80.60.70.4-0.8-0.80.8-0.80.8-0.80.70.4-0.60.50.5-0.6-0.60.50.40.40.10.0
Tibia length0.51.53.50.9-1.31.31.71.51.9-1.4-1.71.7-1.71.7-1.70.6-0.1-0.60.51.4-1.1-1.10.10.0-0.1-0.6-0.9
Ambulatory time before self-admin0.40.71.50.9-0.61.20.80.70.7-1.0-0.90.9-0.90.9-0.91.10.1-1.11.00.30.20.20.90.80.80.50.4
Ambulatory time after self-admin0.40.52.10.5-0.7-0.6-0.20.2-0.30.10.1-0.10.1-0.10.1-0.6-1.50.6-0.50.4-0.7-0.7-1.0-1.4-1.1-1.1-0.7
Bone: tissue strength0.40.51.0-0.40.10.41.00.81.0-0.5-0.90.9-0.90.9-0.9-0.40.20.5-0.61.0-0.5-0.5-0.3-0.1-0.5-0.5-1.0
Total heroin consumption0.20.31.4-1.21.2-0.4-0.5-0.4-0.50.50.5-0.50.5-0.50.5-0.50.80.6-0.7-0.30.10.10.10.40.10.3-0.1
Bone: trabecular number0.61.12.7-0.4-0.20.41.51.21.6-0.5-1.41.4-1.41.4-1.4-0.60.30.6-0.71.5-0.8-0.8-0.7-0.4-0.8-0.9-1.5
Bone: trabecular spacing0.30.31.5-0.10.3-0.6-1.0-0.6-1.20.10.9-0.90.9-0.90.9-0.1-0.50.2-0.1-0.6-0.1-0.1-0.0-0.20.00.00.4
Bone: trabecular thickness0.60.82.2-1.30.7-0.50.70.41.00.3-0.40.4-0.40.4-0.4-1.30.51.4-1.50.9-0.5-0.5-1.1-0.6-1.1-0.8-1.5
Bone: trabecular tissue density2.33.47.11.5-2.20.51.62.31.6-1.9-1.51.5-1.51.5-1.5-0.3-2.50.7-0.72.5-2.7-2.7-1.4-2.1-1.8-2.4-2.3
Water consumed over 24 hours0.10.10.5-0.50.6-0.1-0.3-0.4-0.40.20.3-0.30.3-0.30.3-0.00.7-0.0-0.0-0.50.30.30.30.50.40.40.4
Number of responses in last shaping day2.22.45.7-2.41.7-2.2-1.8-1.9-1.72.21.5-1.51.5-1.51.5-2.11.21.6-1.5-1.11.41.4-1.4-0.6-0.9-0.2-0.4