Hub : Genes

Atad2b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	IL	alternative polyA	NM_001427483.1	0.29	0.15	7.9e-03	0.07	0.13	0.06	0.06	1.1e-02	6.4e-04	1.5e-02	1.3e-02
2	IL	alternative polyA	XM_039113113.2	0.32	0.16	5.8e-03	0.06	0.13	0.08	0.06	1.2e-02	5.7e-04	6.8e-03	1.3e-02
3	IL	alternative polyA	NM_001427483.1	0.33	0.18	5.1e-03	0	0.1	0.06	0.05	2.9e-01	2.3e-03	1.5e-02	2.4e-02
4	IL	alternative polyA	XM_039113113.2	0.29	0.17	8.6e-03	-0	0.09	0.04	0.03	3.7e-01	4.5e-03	3.1e-02	7.8e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4
Bone: apparent density	0.2	0.3	0.7	-0.4	0.0	0.7	-0.8
Area under the delay curve	0.2	0.3	0.4	-0.4	0.4	-0.6	0.6
BMI with tail	2.4	8.3	11.2	3.3	-3.3	2.4	-2.4
BMI without tail	1.9	10.2	12.3	3.5	-3.5	2.8	-2.9
Body weight	1.7	7.5	11.4	3.4	-3.2	2.1	-2.0
Weight adjusted by age	0.2	0.6	0.7	0.7	-0.7	0.8	-0.8
Bone surface	0.0	0.0	0.1	-0.3	0.1	0.1	-0.2
Bone volume	0.1	0.1	0.4	-0.6	0.3	0.1	-0.2
Breakpoint value in progressive ratio session	0.4	0.7	1.2	-1.1	0.9	-0.7	0.6
Number of licking bursts	0.3	0.9	1.7	1.3	-1.2	0.6	-0.6
Context. condit. distance diff. score	0.7	0.9	1.4	0.5	-0.7	1.1	-1.2
Locomotion velocity, session 1	0.1	0.1	0.2	0.4	-0.4	0.1	-0.1
Locomotion distance, session 1	0.3	0.4	0.5	-0.7	0.7	-0.5	0.5
Locomotion velocity, session 2	0.0	0.0	0.1	0.3	-0.2	0.1	-0.1
Locomotion distance, session 2	0.2	0.2	0.3	-0.4	0.4	-0.6	0.6
Locomotion velocity, session 3	0.4	0.4	0.5	0.6	-0.6	0.7	-0.7
Locomotion distance, session 3	0.5	0.5	0.7	0.6	-0.7	0.8	-0.8
Stereotopy head waving bouts, day 3	0.3	0.4	0.8	-0.9	0.7	-0.2	0.1
Stereotopy head waving duration, day 3	0.0	0.0	0.1	-0.3	0.3	-0.0	0.0
Locomotion velocity, session 7	0.1	0.1	0.2	0.4	-0.4	0.3	-0.3
Locomotion distance, session 7	0.9	1.1	1.3	1.1	-1.1	1.0	-1.0
Stereotopy head waving bouts, day 7	0.1	0.1	0.2	0.4	-0.4	0.1	-0.1
Stereotopy head waving duration, day 7	0.0	0.0	0.0	-0.0	0.0	0.0	0.0
Locomotion velocity, session 8	0.1	0.1	0.1	-0.3	0.1	0.3	-0.3
Locomotion distance, session 8	0.1	0.1	0.1	-0.4	0.2	0.3	-0.4
Degree of sensitization distance	0.4	0.4	0.8	0.9	-0.8	0.4	-0.4
Degree of sensitization stereotypy	0.1	0.2	0.4	0.6	-0.5	-0.1	0.2
Conditioned locomotion	0.3	0.3	0.6	-0.3	0.1	0.8	-0.8
Cocaine response after cond. corrected	0.1	0.2	0.3	-0.1	0.2	-0.5	0.5
Cocaine response after cond. not corrected	0.6	0.9	1.1	-0.8	0.9	-1.1	1.1
Cocaine response before conditioning	1.7	2.0	3.0	-1.7	1.7	-1.1	1.1
Saline control response	0.6	0.9	1.3	-1.1	1.1	-0.7	0.7
Bone: connectivity density	0.1	0.2	0.4	-0.1	-0.1	0.5	-0.6
Bone: cortical apparent density	1.0	1.6	2.2	-1.1	1.0	-1.5	1.4
Bone: cortical area	0.0	0.0	0.0	0.2	-0.1	-0.1	0.1
Bone: cortical porosity	1.6	1.7	2.4	-1.6	1.5	-1.0	1.1
Bone: cortical porosity	0.8	0.8	1.5	-1.2	1.1	-0.6	0.6
Bone: cortical thickness	0.4	0.7	1.3	-0.4	0.5	-1.1	1.1
Bone: cortical thickness	0.6	0.7	0.8	-0.9	0.8	-0.9	0.8
Bone: cortical tissue density	0.8	1.3	1.9	-0.9	0.9	-1.4	1.3
Condit. Reinf. active minus inactive responses	0.3	0.3	0.8	0.9	-0.7	-0.1	0.1
Condit. Reinf. active-inactive response ratio	0.4	0.5	1.0	1.0	-0.9	0.2	-0.2
Condit. Reinf. active responses	0.0	0.0	0.0	0.2	-0.1	-0.1	0.1
Condit. Reinf. inactive responses	0.2	0.3	0.7	-0.8	0.7	-0.2	0.1
Incentive salience index mean	0.1	0.1	0.3	0.5	-0.4	-0.0	0.1
Condit. Reinf. lever presses	0.2	0.3	0.4	-0.6	0.6	-0.4	0.5
Condit. Reinf. active minus inactive responses	0.2	0.3	0.5	-0.7	0.6	-0.5	0.5
Condit. Reinf. active-inactive response ratio	0.0	0.1	0.1	-0.3	0.3	-0.1	0.2
Condit. Reinf. active responses	0.6	0.8	1.0	-0.8	0.8	-1.0	1.0
Condit. Reinf. inactive responses	0.2	0.3	0.4	-0.4	0.4	-0.6	0.6
Condit. Reinf. lever presses	2.1	3.0	3.1	-1.7	1.7	-1.7	1.8
Condit. Reinf. lever reinforcers received	0.8	1.2	1.4	-0.9	1.0	-1.2	1.2
Conditioned reinforcement - actives	1.1	4.3	5.8	-2.4	2.3	-1.8	1.7
Conditioned reinforcement - inactives	1.2	3.3	4.7	-2.2	2.1	-1.5	1.5
Conditioned locomotion	3.3	4.8	5.4	-2.3	2.3	-2.1	2.1
Patch foraging indifference point 0 sec	0.2	0.4	0.6	0.5	-0.5	0.8	-0.8
Patch foraging indifference point AUC	0.7	1.8	2.6	1.0	-1.0	1.6	-1.6
Delay disc. indifference point, 0s delay	0.5	0.5	0.9	-0.4	0.5	-0.9	0.9
Delay disc. indifference point, 16s delay	0.0	0.0	0.0	-0.2	0.1	-0.2	0.2
Delay disc. indifference point, 2s delay	1.1	1.2	1.7	-0.9	0.9	-1.3	1.3
Delay disc. indifference point, 24s delay	0.4	0.6	1.1	-1.1	0.8	-0.5	0.4
Delay disc. indifference point, 4s delay	0.2	0.2	0.2	-0.4	0.5	-0.4	0.4
Delay disc. indifference point, 8s delay	0.1	0.2	0.2	-0.4	0.4	-0.5	0.4
Indifference point function ln k	0.9	2.7	2.9	-1.7	1.7	-1.6	1.6
Indifference point function log k	0.9	2.7	2.9	-1.7	1.7	-1.6	1.6
Patch foraging total patch changes 0 sec	0.1	0.4	0.5	0.4	-0.5	0.7	-0.7
Patch foraging total patch changes 12 sec	2.6	3.5	3.7	1.9	-1.9	1.9	-1.8
Patch foraging total patch changes 18 sec	1.3	3.0	3.6	1.5	-1.6	1.9	-1.9
Patch foraging total patch changes 24 sec	0.4	1.3	1.5	1.2	-1.2	1.1	-1.1
Patch foraging total patch changes 6 sec	1.5	2.6	2.8	1.6	-1.6	1.7	-1.6
Patch foraging time to switch 0 sec	0.1	0.5	0.8	0.9	-0.9	0.3	-0.4
Patch foraging water rate 0 sec	0.6	2.3	3.8	-2.0	1.9	-1.0	1.0
Patch foraging water rate 12 sec	0.2	0.8	1.2	-0.7	0.8	-1.0	1.1
Patch foraging water rate 18 sec	2.5	5.5	6.7	-2.5	2.6	-2.1	2.1
Patch foraging water rate 24 sec	0.0	0.0	0.0	0.1	-0.1	0.1	-0.1
Patch foraging water rate 6 sec	1.9	2.9	3.4	-1.8	1.8	-1.5	1.6
Seeking ratio, delayed vs. immediate footshock	0.1	0.1	0.2	0.4	-0.3	0.2	-0.1
Distance traveled before self-admin	0.0	0.0	0.0	0.1	-0.1	0.1	-0.1
Distance traveled after self-admin	0.0	0.0	0.0	-0.2	0.2	0.0	-0.0
Extensor digitorum longus weight	0.5	1.9	3.0	-1.7	1.6	-1.1	1.0
Bone: elastic displacement	0.7	0.9	1.3	-1.2	1.0	-0.8	0.7
Bone: elastic work	1.0	1.4	1.8	-1.3	1.2	-1.1	1.0
Bone: endosteal estimation	0.2	0.5	0.9	0.2	-0.4	0.9	-0.9
Bone: endosteal perimeter	0.6	1.4	1.7	1.0	-1.0	1.3	-1.3
Epididymis fat weight	6.4	32.4	49.2	7.0	-6.5	4.4	-4.3
Delta time in closed arm before/after self-admin	0.2	0.2	0.4	0.2	-0.3	0.6	-0.6
Delta time in open arm before/after self-admin	0.6	0.7	1.0	1.0	-1.0	0.6	-0.6
Diff in mean of infusions in LGA sessions	0.2	0.3	0.4	0.6	-0.6	0.5	-0.5
Delay discount exponential model param	0.2	0.3	0.3	0.6	-0.5	0.6	-0.5
Extinction: sum of active levers before priming	0.1	0.1	0.2	-0.2	0.1	0.4	-0.4
Active lever presses in extinction session 6	0.1	0.1	0.1	-0.3	0.2	0.4	-0.3
Bone: final force	0.0	0.0	0.0	0.2	-0.1	-0.1	0.1
Bone: final moment	0.0	0.0	0.0	0.1	-0.0	-0.1	0.1
Food consumed during 24 hour testing period	0.0	0.1	0.1	-0.3	0.3	-0.1	0.2
Glucose	1.0	1.6	2.1	1.5	-1.5	1.0	-1.1
Heart weight	0.2	0.4	0.6	0.7	-0.7	0.5	-0.4
Delay discount hyperbolic model param	0.2	0.2	0.3	0.5	-0.4	0.6	-0.5
Intermittent access intake day 1-15 change	0.5	2.6	3.3	-1.8	1.7	-1.5	1.4
Intermittent access intake escalation	0.4	2.4	2.9	-1.7	1.6	-1.5	1.4
Intermittent access intake escalation 2	0.7	1.1	1.5	-1.2	1.1	-1.0	0.9
Intermitt. access day 1 inactive lever presses	0.0	0.0	0.0	-0.1	0.2	0.0	0.0
Intermitt. access day 15 inactive lever presses	0.0	0.2	0.4	0.2	-0.2	0.6	-0.6
Intermitt. access escalation Index	0.4	1.2	1.6	1.3	-1.2	1.0	-0.9
Intermittent access day 1 total infusions	0.3	0.8	1.0	-1.0	1.0	-0.8	0.8
Intermittent access day 15 total infusions	1.5	3.7	4.1	-2.0	2.0	-1.9	1.8
Intermittent access terminal intake (last 3 days)	4.5	7.9	8.3	-2.9	2.9	-2.7	2.7
Intermittent access total infusions	3.4	4.0	4.3	-2.1	2.0	-2.0	1.9
Intermittent access day 1 locomotion	2.3	4.2	4.9	-1.9	2.0	-2.2	2.2
Intermittent access day 15 total locomotion	0.6	2.2	2.7	-1.2	1.3	-1.6	1.6
Intermittent access total locomotion	4.5	5.4	6.1	-2.1	2.2	-2.5	2.4
Intermittent access standard deviation	0.2	0.8	1.2	-1.1	1.0	-0.7	0.7
Left kidney weight	0.1	0.6	0.7	0.8	-0.8	0.7	-0.7
Right kidney weight	0.4	2.6	3.5	1.9	-1.8	1.4	-1.3
Cocaine induced anxiety	0.1	0.2	0.4	0.2	-0.4	0.5	-0.6
Post-drug Anxiety	2.4	2.7	2.9	1.7	-1.7	1.6	-1.6
Baseline Anxiety	0.7	1.1	1.9	1.4	-1.1	0.8	-0.7
Tail length	0.0	0.2	0.3	-0.5	0.5	-0.5	0.5
Length with tail	0.0	0.1	0.1	0.2	-0.1	-0.4	0.4
Length without tail	0.0	0.0	0.1	0.3	-0.2	-0.1	0.1
Times rat made contact with spout	0.1	0.1	0.2	-0.4	0.3	0.4	-0.4
Lifetime Intake	3.5	4.3	4.5	-2.1	2.1	-2.1	2.0
Liver weight, left	0.3	0.6	1.2	0.3	0.0	-1.0	1.1
Liver weight, right	1.4	2.4	4.5	2.1	-2.0	0.8	-0.8
Locomotor activity	1.7	2.7	4.2	2.0	-1.9	1.2	-1.2
Locomotor testing distance	1.3	3.1	4.1	2.0	-2.0	1.5	-1.5
Locomotor testing rearing	0.0	0.1	0.2	0.5	-0.4	0.3	-0.3
Locomotion in novel chamber	0.2	0.2	0.3	0.6	-0.4	-0.4	0.4
Locomotion in novel chamber post-restriction	0.0	0.1	0.1	0.3	-0.2	-0.2	0.3
Fecal boli incidents, locomotor time 1	0.4	1.1	1.6	-1.3	1.1	-0.9	0.8
Change in fecal boli incidents, locomotor task	0.5	0.5	0.6	0.8	-0.7	0.7	-0.6
Time >=10cm from walls, locomotor time 1	0.0	0.0	0.1	0.2	-0.2	0.0	-0.2
Bouts of movement, locomotor time 1	0.2	0.3	0.3	-0.5	0.5	-0.6	0.5
Total resting periods, locomotor time 1	0.0	0.0	0.1	-0.3	0.2	-0.2	0.1
Rest time, locomotor task time 1	0.0	0.0	0.0	0.1	-0.1	0.1	-0.1
Distance moved, locomotor task time 1	0.0	0.1	0.2	0.4	-0.3	0.2	-0.1
Vertical activity count, locomotor time 1	0.1	0.5	0.7	-0.5	0.5	-0.8	0.8
Time >=10cm from walls, locomotor time 2	0.0	0.0	0.0	-0.1	-0.1	0.1	-0.2
Bouts of movement, locomotor time 2	0.0	0.1	0.1	-0.3	0.3	-0.4	0.4
Total resting periods, locomotor time 2	0.0	0.0	0.0	-0.1	0.1	-0.1	0.1
Rest time, locomotor task time 2	0.0	0.1	0.1	0.3	-0.3	0.2	-0.2
Distance moved, locomotor task time 2	0.8	1.1	1.3	-1.0	1.0	-1.1	1.1
Vertical activity count, locomotor time 2	0.5	1.2	1.2	-1.0	1.1	-1.1	1.1
Light reinforcement 1	0.1	0.5	0.6	-0.7	0.7	-0.8	0.8
Light reinforcement 2	1.2	2.7	3.7	-1.9	1.8	-1.4	1.3
Bone: marrow area	0.2	0.4	0.7	0.2	-0.3	0.8	-0.8
Bone: maximum diameter	0.2	0.4	0.7	0.4	-0.4	0.8	-0.8
Bone: maximum force	0.0	0.0	0.0	-0.2	0.2	-0.2	0.2
Bone: maximum moment	0.0	0.0	0.1	-0.2	0.2	-0.2	0.2
Mean time between licks in bursts	0.1	0.8	1.0	1.0	-1.0	0.8	-0.8
Mean num. licks in bursts	0.3	0.9	1.9	-1.4	1.2	-0.3	0.3
Cd content in liver	0.7	0.8	0.9	0.9	-0.9	0.8	-0.9
Co content in liver	1.7	2.0	2.4	-1.5	1.5	-1.3	1.3
Cu content in liver	0.4	0.5	0.7	0.8	-0.8	0.6	-0.6
Fe content in liver	0.2	0.2	0.4	-0.6	0.4	0.3	-0.4
K content in liver	0.8	0.8	0.9	0.9	-0.9	0.9	-0.8
Mg content in liver	0.0	0.1	0.1	0.2	-0.2	0.2	-0.2
Mn content in liver	0.1	0.1	0.2	0.1	-0.1	-0.4	0.4
Na content in liver	1.2	1.3	2.0	-1.4	1.4	-0.8	0.8
Rb content in liver	1.9	2.2	3.0	1.2	-1.3	1.7	-1.7
Se content in liver	0.1	0.1	0.1	0.2	-0.1	-0.3	0.3
Sr content in liver	0.1	0.1	0.3	-0.5	0.4	-0.2	0.2
Zn content in liver	0.9	1.1	1.7	1.3	-1.2	0.8	-0.8
Bone: minimum diameter	0.4	0.8	1.5	1.2	-1.1	0.6	-0.5
Time in familiar zone, hab. session 1	0.2	0.2	0.5	0.7	-0.6	0.1	-0.1
Time in novel zone, hab. session 1	0.5	0.6	0.7	0.7	-0.7	0.8	-0.8
Total zone transitions, hab. session 1	0.0	0.0	0.1	-0.3	0.3	0.1	-0.0
Total locomotion distance, hab. session 1	0.6	0.9	1.1	-1.1	1.0	-0.8	0.8
Locomotion velocity, hab. session 1	1.5	2.2	2.8	-1.7	1.6	-1.3	1.3
Time in familiar zone, hab. session 2	0.0	0.0	0.0	-0.0	-0.0	-0.1	0.1
Time in novel zone, hab. session 2	0.5	0.6	0.7	0.8	-0.8	0.7	-0.7
Total zone transitions, hab. session 2	0.3	0.4	0.7	0.3	-0.4	0.8	-0.8
Total locomotion distance, hab. session 2	0.6	0.8	1.2	0.6	-0.7	1.1	-1.1
Locomotion velocity, hab. session 2	0.7	0.9	1.4	0.6	-0.7	1.2	-1.2
Novel to familiar place preference ratio	0.0	0.0	0.1	0.3	-0.2	0.1	-0.1
Novelty place preference	0.1	0.1	0.2	0.4	-0.3	0.0	-0.0
Time in novel zone, NPP test	0.2	0.2	0.4	0.6	-0.6	0.2	-0.2
Total zone transitions, NPP test	0.2	0.3	0.6	0.1	-0.2	0.8	-0.8
Total locomotion distance, NPP test	0.1	0.1	0.2	-0.3	0.2	0.5	-0.5
Locomotion velocity, NPP test	0.1	0.2	0.4	-0.6	0.5	0.2	-0.3
Intraocular pressure	0.9	1.4	2.3	1.5	-1.5	0.7	-0.8
Delta distance traveled before/after self-admin	0.1	0.1	0.2	0.4	-0.3	0.4	-0.3
Delta ambulatory time before/after self-admin	0.1	0.1	0.2	-0.5	0.4	-0.1	0.2
Parametrial fat weight	12.1	28.5	48.8	7.0	-6.4	3.6	-3.4
Pavlov. Cond. lever latency	0.0	0.0	0.1	0.0	0.0	-0.2	0.2
Pavlov. Cond. magazine entry latency	0.5	0.6	0.8	0.6	-0.7	0.8	-0.9
Pavlov. Cond. change in total contacts	0.1	0.1	0.3	-0.2	0.2	-0.5	0.4
Pavlov. Cond. index score	0.1	0.1	0.2	0.2	-0.3	0.4	-0.4
Pavlov. Cond. latency score	0.2	0.3	0.4	0.3	-0.4	0.6	-0.6
Pavlov. Cond. lever contacts	0.0	0.0	0.0	-0.2	0.2	-0.1	0.1
Pavlov. Cond. magazine entry number	0.5	0.7	1.0	-0.6	0.7	-0.9	1.0
Pavlov. Cond. intertrial magazine entries	0.3	0.4	0.7	-0.9	0.8	-0.5	0.4
Pavlov. Cond. lever-magazine prob. diff.	0.0	0.0	0.1	0.0	-0.1	0.3	-0.3
Pavlov. Cond. response bias	0.1	0.1	0.2	-0.0	-0.1	0.4	-0.5
Pavlov. Cond. lever latency	0.3	0.5	0.9	0.9	-0.9	0.2	-0.3
Pavlov. Cond. magazine entry latency	0.2	0.3	0.5	0.3	-0.3	0.7	-0.7
Pavlov. Cond. change in total contacts	0.0	0.0	0.1	-0.3	0.3	0.1	-0.1
Pavlov. Cond. index score	0.2	0.2	0.5	-0.7	0.7	-0.0	0.1
Pavlov. Cond. latency score	0.2	0.3	0.6	-0.7	0.7	0.0	0.0
Pavlov. Cond. lever contacts	0.2	0.2	0.5	-0.7	0.7	-0.1	0.2
Pavlov. Cond. magazine entry number	0.5	0.6	0.9	-0.6	0.6	-0.9	0.9
Pavlov. Cond. intertrial magazine entries	0.1	0.3	0.5	0.2	-0.1	-0.7	0.7
Pavlov. Cond. lever-magazine prob. diff.	0.1	0.1	0.3	-0.5	0.5	0.1	-0.1
Pavlov. Cond. response bias	0.1	0.2	0.4	-0.6	0.5	0.1	-0.1
Time in closed arm before self-admin	0.6	1.0	1.1	0.9	-0.9	1.1	-1.0
Time in closed arm after self-admin	0.2	0.3	0.4	0.6	-0.5	0.4	-0.4
Time in open arm before self-admin	0.6	0.7	0.9	-0.7	0.7	-1.0	0.9
Time in open arm after self-admin	0.0	0.0	0.0	0.1	-0.1	-0.2	0.1
Bone: periosteal estimation	0.0	0.1	0.2	0.0	-0.1	0.4	-0.4
Bone: periosteal perimeter	0.3	0.7	0.9	0.7	-0.7	1.0	-0.9
Bone: post-yield work	0.1	0.2	0.5	-0.7	0.6	0.3	-0.3
Progressive ratio test 1 active lever presses	1.0	1.8	1.8	-1.3	1.4	-1.3	1.3
Progressive ratio test 1 breakpoint	0.9	1.5	1.7	-1.3	1.3	-1.2	1.2
Progressive ratio test 1 inactive lever presses	0.2	0.4	0.7	-0.7	0.8	-0.5	0.6
Progressive ratio test 2 active lever presses	4.4	6.2	6.5	-2.6	2.5	-2.5	2.4
Progressive ratio test 2 breakpoint	5.4	6.9	7.0	-2.6	2.6	-2.6	2.6
Progressive ratio test 2 inactive lever presses	1.1	3.3	4.1	-2.0	2.0	-1.6	1.6
Incentive Sensitization - Responses	2.2	6.1	6.6	-2.5	2.4	-2.6	2.5
Incentive Sensitization - Breakpoint	3.0	6.8	7.5	-2.5	2.5	-2.7	2.7
Sum of active levers in priming session hrs 5-6	0.2	0.2	0.3	0.3	-0.4	0.5	-0.5
Progressive ratio	0.5	1.5	1.6	1.2	-1.2	1.3	-1.3
Food seeking constrained by brief footshock	1.5	1.9	3.6	-1.9	1.7	-0.8	0.7
Seeking ratio, punishment vs. effort	0.8	1.8	2.7	-1.6	1.5	-1.0	1.0
Retroperitoneal fat weight	15.4	68.7	114.6	10.7	-9.8	5.8	-5.5
Reaction time number correct	0.0	0.1	0.3	-0.5	0.5	-0.2	0.2
Reaction time mean minus median	0.2	1.0	1.9	1.4	-1.4	0.4	-0.5
Reaction time mean minus median AUC	0.2	1.2	2.1	1.4	-1.4	0.5	-0.6
Reaction time num false alarms	3.1	5.2	5.7	2.4	-2.4	2.2	-2.2
Reaction time num false alarms AUC	2.0	4.6	5.5	2.4	-2.3	2.0	-1.9
Reaction time trials correct on left	0.0	0.1	0.3	-0.5	0.5	-0.2	0.2
Reaction time trials on left	0.0	0.1	0.2	-0.4	0.4	-0.2	0.2
Reaction time mean	0.1	0.2	0.4	0.6	-0.6	-0.4	0.3
Reaction time mean AUC	0.1	0.2	0.3	0.5	-0.5	-0.4	0.3
Median of all reaction times	0.1	0.2	0.5	0.1	-0.1	-0.7	0.6
Reaction time omissions	2.3	3.8	5.5	2.3	-2.3	1.4	-1.5
Reaction time false alarm rate	2.5	3.4	4.5	2.1	-2.0	1.6	-1.6
Reaction time premature initiation rate	0.0	0.1	0.1	-0.2	0.2	0.3	-0.3
Reaction time premature initiations	0.0	0.1	0.3	-0.5	0.5	0.2	-0.2
Std. dev. reaction times	0.4	1.5	2.6	1.6	-1.6	0.6	-0.7
Reaction time trials completed	0.0	0.1	0.2	-0.4	0.4	-0.2	0.2
Reaction time trials AUC	0.0	0.1	0.2	-0.4	0.4	-0.3	0.3
Run reversals in cocaine runway, females	0.2	0.2	0.5	-0.7	0.6	0.1	-0.1
Run reversals in cocaine runway, males	1.1	1.3	1.5	-1.2	1.2	-1.0	1.1
Latency to leave start box in cocaine runway	1.8	2.4	3.9	0.9	-1.2	1.9	-2.0
Latency to leave start box in cocaine runway, F	2.0	2.5	3.7	1.0	-1.2	1.9	-1.9
Latency to leave start box in cocaine runway, M	0.4	0.4	0.8	0.2	-0.4	0.8	-0.9
Std. dev. time between licks in bursts	0.2	0.4	0.5	0.7	-0.7	0.6	-0.6
Total sessions with >9 infusions	3.8	4.7	5.1	-2.1	2.1	-2.3	2.2
Short access day 1 total inactive lever presses	1.0	2.0	2.9	-1.7	1.7	-1.1	1.1
Short access day 10 total inactive lever presses	0.4	2.5	3.4	1.3	-1.4	1.8	-1.8
Short access day 1 total infusions	0.7	1.3	1.4	-1.2	1.2	-1.2	1.1
Short access day 10 total infusions	1.5	2.5	2.8	-1.7	1.7	-1.5	1.4
Short access total infusions	1.6	2.3	2.4	-1.5	1.5	-1.5	1.5
Short access day 1 locomotion	1.1	1.8	2.1	-1.2	1.2	-1.5	1.4
Short access day 10 total locomotion	0.5	2.2	2.6	-1.4	1.4	-1.6	1.5
Short access total locomotion	3.0	4.5	5.5	-1.9	1.9	-2.3	2.3
One hour access (0.3 mA shock)	3.3	4.0	5.4	-2.3	2.1	-1.8	1.7
Compulsive drug intake	0.3	0.4	0.5	0.7	-0.7	0.5	-0.6
One hour access (shock baseline)	2.1	5.6	6.8	-2.6	2.5	-2.2	2.1
Social response proportion	0.8	1.0	1.2	-0.9	0.9	-1.1	1.1
Social responses	0.2	0.2	0.3	0.6	-0.5	0.3	-0.3
Social time	0.6	0.9	1.5	-0.5	0.6	-1.2	1.2
Soleus weight	0.8	2.5	4.9	-2.2	1.9	-0.8	0.7
Bone: stiffness	0.0	0.0	0.0	-0.1	0.2	-0.1	0.2
Tibialis anterior weight	0.2	0.8	1.4	-1.2	1.0	-0.6	0.6
Time to tail flick, vehicle, before self-admin	0.1	0.1	0.2	0.2	-0.1	-0.5	0.5
Time to tail flick, vehicle, after self-admin	2.1	4.3	6.0	2.5	-2.4	1.7	-1.7
Time to tail flick, test, before self-admin	1.9	2.1	2.2	-1.5	1.4	-1.5	1.5
Time to tail flick, test, after self-admin	0.8	0.9	1.1	-1.0	0.9	-0.9	0.9
Delta time to tail flick, vehicle, before/after SA	2.2	2.4	2.4	1.5	-1.6	1.5	-1.5
Delta time to tail flick, test, before/after SA	0.1	0.1	0.3	-0.6	0.4	-0.1	0.1
Tibia length	0.1	0.2	0.4	0.1	0.1	-0.6	0.6
Ambulatory time before self-admin	0.0	0.0	0.0	0.1	-0.1	-0.0	0.0
Ambulatory time after self-admin	0.0	0.0	0.1	-0.2	0.2	0.0	0.0
Bone: tissue strength	0.4	0.5	0.8	-0.2	0.3	-0.9	0.9
Total heroin consumption	2.6	3.0	4.2	-2.1	1.9	-1.5	1.4
Bone: trabecular number	0.1	0.2	0.3	-0.5	0.3	0.4	-0.5
Bone: trabecular spacing	0.4	0.6	1.1	-0.2	0.4	-1.0	1.0
Bone: trabecular thickness	0.8	1.1	1.5	0.8	-0.9	1.2	-1.2
Bone: trabecular tissue density	0.1	0.1	0.2	0.0	-0.0	0.4	-0.4
Water consumed over 24 hours	0.5	1.0	1.1	0.9	-1.0	1.0	-1.1
Number of responses in last shaping day	0.0	0.0	0.1	-0.3	0.2	0.1	-0.1