Hub : Genes

Asic1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Asic1 0.21 0.13 0.0e+00 0.19 0.2 0.19 0.19 6.2e-21 2.4e-21 7.3e-21 5.6e-21
2 Brain isoform ratio XM_017595126.2 0.04 0.03 2.3e-04 0.02 0.03 0.02 0.02 2.5e-03 1.3e-03 3.9e-03 3.7e-03
3 LHb gene expression Asic1 0.16 0.12 2.2e-03 0.1 0.08 0.07 0.11 3.0e-03 6.6e-03 1.1e-02 1.5e-03
4 Brain alternative TSS XM_017595126.2 0.04 0.03 4.4e-05 0.03 0.03 0.03 0.03 1.5e-03 1.0e-03 1.6e-03 1.5e-03
5 NAcc alternative TSS XM_017595126.2 0.12 0.08 1.1e-16 0.14 0.14 0.15 0.16 9.1e-16 2.5e-16 1.9e-17 1.4e-17
6 NAcc alternative TSS XM_017595126.2 0.04 0.03 2.2e-06 0.05 0.05 0.05 0.01 7.1e-07 1.5e-06 4.2e-06 1.4e-02
7 NAcc isoform ratio XM_017595125.2 0.02 0.02 5.6e-03 0.02 0.02 0.02 0.02 4.6e-03 3.9e-03 4.0e-03 5.3e-03
8 OFC gene expression Asic1 0.34 0.21 1.7e-03 0.07 -0.01 0.05 0.06 1.1e-02 8.8e-01 2.8e-02 1.7e-02
9 Adipose gene expression Asic1 0.36 0.18 0.0e+00 0.34 0.33 0.34 0.34 8.9e-39 4.6e-38 1.1e-38 1.4e-38
10 BLA gene expression Asic1 0.09 0.08 3.2e-04 0.04 0.06 0.05 0.04 2.1e-03 3.1e-04 1.7e-03 2.7e-03
11 BLA intron excision ratio chr7_130799643_130800530 0.04 0.04 9.4e-03 0.06 0.02 0.04 0.04 6.5e-04 2.7e-02 4.0e-03 2.9e-03
12 BLA intron excision ratio chr7_130800022_130800530 0.04 0.04 8.2e-03 0.06 0.02 0.04 0.04 6.0e-04 2.2e-02 4.0e-03 2.8e-03
13 BLA mRNA stability Asic1 0.05 0.04 3.8e-03 0.08 0.03 0.06 0.06 3.6e-05 6.6e-03 3.6e-04 2.6e-04
14 IL gene expression Asic1 0.2 0.16 5.7e-03 0.04 0.09 0.07 0.01 3.9e-02 3.7e-03 7.2e-03 1.7e-01
15 NAcc isoform ratio XM_017595126.2 0.16 0.12 0.0e+00 0.17 0.18 0.21 0.09 1.1e-19 1.2e-20 1.3e-23 8.1e-11
16 PL gene expression Asic1 0.15 0.11 1.2e-08 0.06 0.07 0.07 0.07 1.0e-07 1.9e-08 6.2e-08 6.1e-08
17 Brain mRNA stability Asic1 0.09 0.06 4.4e-05 0.04 0.05 0.04 0.04 5.4e-05 1.6e-05 8.4e-05 5.4e-05
18 Brain gene expression Asic1 0.13 0.09 2.8e-05 0.03 0.04 0.02 0.03 6.4e-04 1.1e-04 2.5e-03 7.6e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density6.711.217.3-3.93.8-4.23.73.5-3.6-3.53.53.4-3.3-3.43.4-2.8-2.8-3.1-2.62.6-2.2
Area under the delay curve1.11.11.6-1.11.1-1.01.11.2-1.3-1.11.21.0-1.1-1.01.0-1.1-1.0-1.1-1.01.0-0.9
BMI with tail4.012.915.3-3.93.9-3.83.93.7-3.5-3.83.73.6-3.6-3.73.7-3.9-3.3-3.2-3.23.2-2.8
BMI without tail0.20.51.1-0.40.40.20.50.7-0.7-0.60.60.6-0.7-0.70.7-0.8-0.9-0.5-0.91.0-1.1
Body weight4.619.425.9-4.94.8-5.14.74.8-4.9-4.55.14.3-4.3-4.34.3-4.6-3.7-4.2-3.63.5-3.1
Weight adjusted by age0.50.61.9-0.80.8-1.40.71.0-1.2-0.61.00.4-0.4-0.50.5-0.7-0.1-0.9-0.00.00.1
Bone surface8.915.721.5-4.54.5-4.64.44.1-4.2-4.24.14.1-4.0-4.14.1-3.5-3.4-3.6-3.33.3-2.8
Bone volume8.213.916.8-4.14.1-4.04.13.8-3.9-3.93.93.9-3.8-3.93.9-3.4-3.4-3.3-3.33.3-3.0
Breakpoint value in progressive ratio session0.10.10.5-0.30.3-0.60.20.4-0.5-0.20.70.2-0.1-0.10.1-0.20.0-0.50.1-0.10.1
Number of licking bursts1.31.62.91.2-1.20.9-1.2-1.61.71.2-1.6-1.21.21.2-1.20.81.21.41.1-1.11.1
Context. condit. distance diff. score0.10.20.3-0.50.5-0.50.50.3-0.3-0.50.50.4-0.5-0.40.40.2-0.4-0.3-0.40.4-0.3
Locomotion velocity, session 13.84.15.31.9-1.91.2-2.0-2.01.82.1-1.9-2.12.22.1-2.12.32.31.72.3-2.32.3
Locomotion distance, session 12.63.43.82.0-2.01.8-2.0-1.91.91.9-1.9-1.91.91.9-1.91.81.81.71.7-1.71.6
Locomotion velocity, session 20.30.30.70.6-0.60.6-0.6-0.50.50.6-0.6-0.60.60.6-0.60.80.50.40.5-0.50.5
Locomotion distance, session 22.94.15.52.1-2.11.8-2.1-2.02.02.1-2.1-2.12.12.1-2.12.31.91.71.9-1.91.8
Locomotion velocity, session 34.35.16.12.4-2.42.2-2.4-2.52.42.4-2.4-2.32.32.3-2.31.62.12.22.1-2.11.9
Locomotion distance, session 32.73.05.92.1-2.12.4-2.0-1.81.71.9-1.7-1.81.71.8-1.81.61.31.51.3-1.20.9
Stereotopy head waving bouts, day 30.10.11.0-0.30.3-1.00.30.2-0.2-0.10.20.10.0-0.10.1-0.40.3-0.20.4-0.40.6
Stereotopy head waving duration, day 30.10.10.6-0.10.1-0.8-0.0-0.10.10.2-0.1-0.20.30.2-0.2-0.30.60.10.6-0.60.8
Locomotion velocity, session 72.83.04.41.6-1.60.8-1.7-1.61.51.8-1.3-1.81.91.8-1.81.92.01.42.1-2.12.1
Locomotion distance, session 73.84.85.42.2-2.21.8-2.3-2.22.02.3-1.9-2.32.32.3-2.32.22.31.82.3-2.32.2
Stereotopy head waving bouts, day 70.50.50.7-0.80.8-0.80.80.7-0.7-0.80.80.9-0.7-0.90.9-0.5-0.6-0.6-0.60.6-0.5
Stereotopy head waving duration, day 71.01.21.5-1.21.2-1.21.21.0-1.0-1.21.11.2-1.1-1.21.2-1.1-1.0-0.9-1.01.0-0.9
Locomotion velocity, session 80.50.61.30.5-0.50.0-0.6-0.80.90.7-0.7-0.70.80.7-0.71.10.90.71.0-1.01.0
Locomotion distance, session 81.21.83.81.3-1.31.3-1.3-1.51.51.3-1.3-1.31.31.3-1.32.01.21.31.2-1.21.1
Degree of sensitization distance0.10.10.4-0.20.2-0.60.10.1-0.1-0.00.1-0.00.10.0-0.00.10.3-0.10.3-0.30.4
Degree of sensitization stereotypy0.60.71.0-0.70.7-0.30.80.7-0.7-0.80.81.0-0.9-1.01.0-0.6-1.0-0.6-1.01.0-1.0
Conditioned locomotion0.00.10.30.0-0.0-0.2-0.0-0.30.50.1-0.4-0.10.10.1-0.1-0.30.20.30.2-0.20.3
Cocaine response after cond. corrected0.00.00.2-0.00.0-0.00.00.2-0.2-0.00.40.1-0.00.1-0.1-0.4-0.0-0.2-0.00.0-0.1
Cocaine response after cond. not corrected0.20.20.40.6-0.60.7-0.5-0.40.30.5-0.3-0.40.40.5-0.5-0.10.30.30.3-0.30.1
Cocaine response before conditioning2.02.44.01.8-1.82.0-1.7-1.81.81.6-1.9-1.51.51.5-1.51.41.21.61.1-1.10.9
Saline control response0.10.10.2-0.10.1-0.40.0-0.30.40.0-0.5-0.10.10.1-0.10.50.20.30.2-0.30.4
Bone: connectivity density3.55.511.6-2.82.8-3.42.72.4-2.5-2.52.42.4-2.3-2.42.4-2.0-1.7-2.2-1.61.6-1.2
Bone: cortical apparent density0.10.20.30.6-0.60.6-0.6-0.40.40.5-0.2-0.50.50.4-0.4-0.10.40.30.4-0.40.3
Bone: cortical area5.48.113.6-3.33.3-3.73.23.0-3.1-3.03.02.9-2.8-2.82.8-2.7-2.3-2.6-2.22.2-1.8
Bone: cortical porosity0.10.10.50.1-0.00.60.00.00.0-0.2-0.00.2-0.3-0.20.2-0.3-0.50.0-0.60.6-0.7
Bone: cortical porosity0.10.10.80.3-0.30.9-0.2-0.20.20.1-0.3-0.0-0.00.1-0.1-0.0-0.30.2-0.40.4-0.5
Bone: cortical thickness1.42.34.8-1.81.8-2.21.71.5-1.5-1.61.61.5-1.5-1.51.5-1.7-1.1-1.3-1.11.0-0.8
Bone: cortical thickness0.30.40.80.4-0.4-0.1-0.4-0.60.50.5-0.6-0.60.60.6-0.60.50.80.50.8-0.80.9
Bone: cortical tissue density0.20.30.50.7-0.70.7-0.7-0.50.40.6-0.3-0.60.60.5-0.50.10.50.40.5-0.50.4
Condit. Reinf. active minus inactive responses0.10.10.10.3-0.30.2-0.3-0.30.20.3-0.2-0.30.30.3-0.30.40.30.30.3-0.30.3
Condit. Reinf. active-inactive response ratio0.10.10.3-0.40.4-0.60.40.3-0.4-0.40.30.3-0.3-0.30.3-0.3-0.2-0.2-0.20.2-0.1
Condit. Reinf. active responses0.70.91.01.0-1.00.9-1.0-1.00.91.0-0.9-1.01.01.0-1.01.00.90.90.9-0.90.8
Condit. Reinf. inactive responses2.63.03.71.9-1.91.9-1.9-1.81.81.8-1.7-1.81.81.8-1.81.81.61.61.6-1.51.4
Incentive salience index mean0.00.00.0-0.00.0-0.10.0-0.0-0.1-0.00.1-0.0-0.00.0-0.00.1-0.00.0-0.00.00.0
Condit. Reinf. lever presses0.50.60.8-0.70.7-0.30.70.9-0.9-0.80.90.8-0.8-0.80.8-0.5-0.9-0.7-0.90.9-0.9
Condit. Reinf. active minus inactive responses0.91.12.4-0.80.8-0.00.90.7-0.3-1.00.41.2-1.2-1.21.2-1.1-1.4-0.5-1.51.5-1.5
Condit. Reinf. active-inactive response ratio0.90.92.7-0.50.60.50.70.6-0.1-0.90.31.0-1.0-1.11.1-0.7-1.4-0.4-1.51.5-1.6
Condit. Reinf. active responses0.10.20.6-0.10.10.40.20.10.1-0.3-0.00.4-0.4-0.40.4-0.5-0.6-0.0-0.70.7-0.8
Condit. Reinf. inactive responses0.70.81.11.0-1.00.9-1.0-0.90.71.0-0.7-1.01.01.0-1.00.60.90.70.9-0.90.8
Condit. Reinf. lever presses0.00.00.1-0.00.00.00.0-0.10.3-0.0-0.30.0-0.00.0-0.0-0.1-0.00.1-0.00.0-0.0
Condit. Reinf. lever reinforcers received0.10.10.70.3-0.30.8-0.2-0.40.60.1-0.6-0.00.00.1-0.1-0.1-0.20.4-0.30.3-0.4
Conditioned reinforcement - actives1.01.02.01.2-1.21.4-1.1-0.91.01.1-0.9-1.01.00.9-0.91.10.80.70.8-0.70.6
Conditioned reinforcement - inactives1.82.03.01.6-1.61.7-1.6-1.51.51.5-1.5-1.41.41.4-1.41.41.21.21.2-1.21.0
Conditioned locomotion0.10.20.50.5-0.50.7-0.4-0.50.60.4-0.5-0.40.30.3-0.30.40.20.50.2-0.20.1
Patch foraging indifference point 0 sec5.89.411.03.0-3.02.1-3.0-3.33.03.1-3.0-3.33.23.2-3.23.23.22.83.2-3.23.1
Patch foraging indifference point AUC0.20.31.00.5-0.50.7-0.5-0.71.00.5-0.9-0.30.40.3-0.30.30.30.60.2-0.20.1
Delay disc. indifference point, 0s delay1.92.12.6-1.51.5-1.21.51.4-1.3-1.51.41.6-1.5-1.61.6-1.5-1.4-1.2-1.41.4-1.3
Delay disc. indifference point, 16s delay0.90.91.4-1.01.0-1.01.01.1-1.1-1.01.20.9-0.9-0.90.9-1.0-0.9-1.0-0.80.8-0.8
Delay disc. indifference point, 2s delay1.82.02.7-1.51.5-1.31.51.6-1.6-1.51.61.4-1.5-1.41.4-1.1-1.3-1.4-1.31.3-1.2
Delay disc. indifference point, 24s delay0.70.61.4-0.90.9-1.20.90.8-1.0-0.80.90.7-0.7-0.70.7-1.2-0.5-0.7-0.50.5-0.3
Delay disc. indifference point, 4s delay1.11.21.4-1.01.0-0.61.01.1-1.1-1.11.11.2-1.1-1.11.1-0.9-1.2-1.0-1.21.2-1.2
Delay disc. indifference point, 8s delay1.41.42.4-1.41.4-1.51.31.4-1.5-1.21.41.0-1.1-1.01.0-1.2-0.9-1.3-0.90.8-0.7
Indifference point function ln k4.76.68.1-2.72.7-2.62.72.8-2.8-2.72.82.4-2.6-2.62.6-2.6-2.4-2.4-2.32.3-2.1
Indifference point function log k4.76.68.1-2.72.7-2.62.72.8-2.8-2.72.82.4-2.6-2.62.6-2.6-2.4-2.4-2.32.3-2.1
Patch foraging total patch changes 0 sec5.58.810.22.9-2.92.1-2.9-3.22.93.0-2.9-3.23.13.1-3.13.23.12.83.0-3.13.0
Patch foraging total patch changes 12 sec5.87.58.72.7-2.71.9-2.7-2.92.82.8-2.6-2.82.82.8-2.83.02.82.52.8-2.82.7
Patch foraging total patch changes 18 sec7.19.211.33.1-3.12.6-3.1-3.33.43.1-3.3-3.13.13.0-3.03.22.92.92.9-2.92.7
Patch foraging total patch changes 24 sec4.45.46.82.3-2.31.8-2.4-2.62.62.4-2.5-2.42.42.3-2.32.32.32.32.3-2.32.2
Patch foraging total patch changes 6 sec6.59.711.13.1-3.12.2-3.2-3.33.13.2-3.1-3.23.33.2-3.22.93.32.83.2-3.23.2
Patch foraging time to switch 0 sec2.03.14.12.0-2.01.7-2.0-1.61.42.0-1.7-1.91.91.9-1.91.51.71.31.7-1.71.5
Patch foraging water rate 0 sec2.84.55.4-2.32.3-2.02.32.0-1.9-2.32.12.2-2.2-2.22.2-2.0-2.1-1.7-2.02.0-1.8
Patch foraging water rate 12 sec2.33.55.3-2.22.2-2.32.21.8-1.7-2.11.62.0-1.9-1.81.8-2.0-1.6-1.5-1.61.5-1.3
Patch foraging water rate 18 sec0.40.50.8-0.80.8-0.60.80.7-0.8-0.80.90.7-0.8-0.70.7-0.6-0.7-0.5-0.70.7-0.6
Patch foraging water rate 24 sec4.36.06.9-2.62.6-2.22.62.6-2.3-2.62.42.6-2.6-2.52.5-2.4-2.4-2.2-2.42.4-2.2
Patch foraging water rate 6 sec5.07.28.2-2.82.9-2.32.92.8-2.6-2.92.82.8-2.8-2.72.7-2.5-2.7-2.4-2.72.6-2.5
Seeking ratio, delayed vs. immediate footshock0.50.60.9-0.80.8-0.60.90.6-0.4-0.90.30.9-0.9-0.90.9-0.7-0.9-0.5-1.01.0-0.9
Distance traveled before self-admin2.22.32.81.6-1.61.2-1.6-1.51.21.6-1.1-1.61.61.6-1.61.71.61.31.7-1.61.6
Distance traveled after self-admin0.50.50.80.7-0.70.6-0.7-0.90.60.8-0.4-0.70.80.7-0.70.70.80.70.8-0.80.8
Extensor digitorum longus weight4.417.419.9-4.44.4-4.04.44.5-4.4-4.34.44.3-4.2-4.34.3-4.1-3.9-3.9-3.83.8-3.6
Bone: elastic displacement6.06.87.52.7-2.72.1-2.7-2.72.62.7-2.7-2.72.72.7-2.72.22.72.42.7-2.62.5
Bone: elastic work0.00.00.2-0.10.0-0.30.00.2-0.40.00.3-0.00.10.1-0.1-0.40.2-0.20.2-0.20.2
Bone: endosteal estimation6.514.318.1-4.34.2-4.24.24.0-4.0-4.03.83.9-3.9-3.93.9-2.8-3.4-3.5-3.33.3-2.9
Bone: endosteal perimeter6.012.515.5-3.93.9-3.73.93.6-3.5-3.83.43.7-3.7-3.73.7-3.0-3.3-3.0-3.33.2-2.9
Epididymis fat weight0.00.00.3-0.30.3-0.60.20.1-0.0-0.10.20.0-0.1-0.10.1-0.10.1-0.10.1-0.10.3
Delta time in closed arm before/after self-admin0.10.10.4-0.40.4-0.60.30.3-0.2-0.30.30.2-0.3-0.20.2-0.2-0.2-0.2-0.20.2-0.1
Delta time in open arm before/after self-admin3.63.45.22.0-2.02.1-2.0-2.12.11.9-2.3-1.81.81.8-1.81.81.61.91.5-1.51.3
Diff in mean of infusions in LGA sessions1.31.52.7-1.31.3-1.41.21.6-1.6-1.21.61.0-1.1-1.01.0-1.0-0.9-1.4-0.90.9-0.7
Delay discount exponential model param1.11.11.61.1-1.11.0-1.1-1.21.31.1-1.2-1.01.10.9-0.91.11.01.11.0-1.00.9
Extinction: sum of active levers before priming0.60.61.0-0.80.8-0.80.80.9-0.9-0.81.00.8-0.8-0.80.8-0.8-0.7-0.9-0.70.7-0.6
Active lever presses in extinction session 60.10.10.5-0.40.3-0.70.30.4-0.4-0.20.60.3-0.2-0.20.2-0.2-0.0-0.50.0-0.00.1
Bone: final force9.815.819.0-4.44.3-4.24.34.2-4.2-4.24.14.1-4.1-4.04.0-3.8-3.6-3.7-3.53.5-3.2
Bone: final moment11.218.121.5-4.64.6-4.44.64.5-4.4-4.54.44.4-4.4-4.34.3-4.1-3.9-3.9-3.83.8-3.5
Food consumed during 24 hour testing period1.31.62.1-1.51.5-1.41.41.3-1.2-1.41.31.3-1.3-1.31.3-1.0-1.2-1.2-1.21.2-1.0
Glucose0.40.61.20.5-0.5-0.1-0.5-1.01.10.6-1.0-0.70.70.6-0.60.70.90.90.9-0.91.1
Heart weight0.10.10.2-0.30.3-0.40.30.2-0.2-0.30.40.2-0.3-0.30.3-0.4-0.3-0.2-0.30.3-0.2
Delay discount hyperbolic model param1.11.21.71.1-1.11.0-1.1-1.21.31.1-1.3-1.11.11.0-1.01.11.11.11.0-1.01.0
Intermittent access intake day 1-15 change0.30.31.50.7-0.71.2-0.6-0.50.70.4-0.5-0.30.30.3-0.3-0.0-0.10.4-0.20.2-0.4
Intermittent access intake escalation0.20.21.00.4-0.31.0-0.3-0.10.30.1-0.10.0-0.1-0.00.0-0.3-0.40.0-0.50.5-0.7
Intermittent access intake escalation 20.30.21.70.6-0.61.3-0.5-0.40.60.3-0.4-0.20.10.3-0.3-0.1-0.30.3-0.30.3-0.6
Intermitt. access day 1 inactive lever presses0.40.41.90.8-0.81.4-0.7-0.70.80.6-0.7-0.50.40.4-0.40.40.10.70.1-0.1-0.1
Intermitt. access day 15 inactive lever presses0.10.21.20.5-0.51.1-0.4-0.30.40.3-0.3-0.20.10.3-0.30.3-0.20.3-0.20.2-0.4
Intermitt. access escalation Index0.80.70.90.8-0.80.4-0.8-0.90.70.8-0.9-0.90.90.9-0.90.80.90.80.9-0.91.0
Intermittent access day 1 total infusions1.11.32.01.2-1.21.2-1.2-1.11.11.2-1.1-1.21.21.1-1.11.41.01.01.0-1.00.9
Intermittent access day 15 total infusions1.51.73.51.6-1.61.9-1.5-1.41.41.4-1.3-1.31.31.2-1.21.30.91.10.9-0.90.6
Intermittent access terminal intake (last 3 days)1.51.73.71.6-1.61.9-1.5-1.41.41.4-1.3-1.31.21.2-1.21.40.91.20.8-0.80.6
Intermittent access total infusions1.51.63.41.6-1.61.8-1.5-1.31.31.4-1.3-1.31.21.2-1.21.40.91.10.9-0.90.6
Intermittent access day 1 locomotion1.31.42.01.2-1.21.0-1.2-1.11.01.2-1.1-1.31.21.1-1.11.41.21.01.2-1.21.1
Intermittent access day 15 total locomotion1.11.12.01.2-1.21.4-1.2-1.21.31.1-1.2-1.11.01.0-1.00.90.81.10.8-0.80.6
Intermittent access total locomotion3.64.14.82.2-2.22.1-2.1-2.22.12.1-2.1-2.12.02.0-2.02.01.91.91.8-1.81.7
Intermittent access standard deviation0.10.10.50.2-0.20.7-0.10.10.1-0.00.10.1-0.1-0.10.10.1-0.4-0.1-0.50.5-0.7
Left kidney weight1.02.85.1-1.51.5-1.01.61.8-2.1-1.62.31.6-1.6-1.61.6-1.7-1.7-1.7-1.61.6-1.6
Right kidney weight2.16.010.2-2.62.6-2.72.52.7-3.2-2.43.12.3-2.3-2.32.3-2.4-2.0-2.5-1.91.9-1.7
Cocaine induced anxiety0.91.02.1-1.01.0-1.01.01.3-1.4-1.01.30.9-0.9-0.90.9-0.3-0.8-1.2-0.70.7-0.7
Post-drug Anxiety4.75.37.2-2.52.5-2.42.42.5-2.7-2.42.52.3-2.3-2.32.3-1.9-2.1-2.2-2.02.0-1.8
Baseline Anxiety0.80.81.9-1.01.0-1.11.00.8-0.9-0.90.90.9-0.9-0.90.9-1.4-0.8-0.6-0.70.7-0.6
Tail length0.00.10.40.3-0.30.6-0.3-0.0-0.30.20.1-0.20.20.2-0.20.20.00.0-0.00.0-0.1
Length with tail1.65.89.0-2.62.6-2.72.52.7-3.0-2.43.02.3-2.3-2.32.3-2.4-2.0-2.4-1.91.9-1.6
Length without tail4.59.817.2-3.63.6-4.23.53.3-3.4-3.23.63.1-3.0-3.03.0-3.2-2.4-3.0-2.32.2-1.8
Times rat made contact with spout0.00.00.10.2-0.20.4-0.2-0.20.30.1-0.1-0.10.10.1-0.10.2-0.00.2-0.00.0-0.1
Lifetime Intake2.12.43.61.8-1.81.9-1.8-1.61.51.7-1.5-1.61.61.5-1.51.61.31.31.3-1.21.0
Liver weight, left1.42.33.4-1.71.7-1.81.71.5-1.6-1.61.31.5-1.5-1.61.6-1.6-1.3-1.3-1.31.2-1.0
Liver weight, right1.42.33.2-1.61.6-1.61.61.7-1.8-1.61.71.5-1.5-1.41.4-1.5-1.3-1.5-1.31.3-1.1
Locomotor activity1.01.62.41.5-1.51.5-1.4-1.00.61.4-0.5-1.51.31.4-1.41.21.20.91.2-1.21.0
Locomotor testing distance2.94.86.02.4-2.42.4-2.4-2.21.82.4-1.7-2.42.32.4-2.42.02.11.92.0-2.01.8
Locomotor testing rearing2.03.14.12.0-2.02.0-1.9-1.81.61.9-1.5-1.91.81.9-1.91.81.61.61.5-1.51.4
Locomotion in novel chamber2.53.14.5-1.61.6-0.81.71.7-1.4-1.81.41.8-1.9-1.91.9-1.9-2.1-1.5-2.12.1-2.1
Locomotion in novel chamber post-restriction0.50.61.0-0.60.6-0.20.70.7-0.6-0.70.70.8-0.8-0.80.8-0.8-0.9-0.5-1.00.9-1.0
Fecal boli incidents, locomotor time 11.21.32.41.3-1.31.5-1.2-1.41.31.2-1.3-1.11.11.2-1.20.80.81.20.8-0.70.6
Change in fecal boli incidents, locomotor task0.40.41.6-0.80.8-1.30.70.8-0.8-0.60.70.5-0.4-0.40.4-0.7-0.2-0.8-0.10.10.0
Time >=10cm from walls, locomotor time 10.40.41.10.4-0.4-0.1-0.5-0.50.40.6-0.4-0.60.70.7-0.70.60.90.30.9-1.01.1
Bouts of movement, locomotor time 10.00.00.1-0.10.1-0.20.10.00.0-0.00.1-0.0-0.00.1-0.1-0.30.0-0.10.0-0.00.1
Total resting periods, locomotor time 10.40.40.70.6-0.60.3-0.6-0.60.70.6-0.6-0.70.70.8-0.80.30.70.50.7-0.70.7
Rest time, locomotor task time 10.70.81.30.9-0.90.6-0.9-0.90.90.9-0.9-1.00.91.1-1.10.90.90.70.8-0.90.8
Distance moved, locomotor task time 10.00.00.0-0.00.0-0.10.0-0.10.10.0-0.10.10.0-0.20.2-0.00.10.10.1-0.10.2
Vertical activity count, locomotor time 10.91.01.4-1.11.1-1.11.11.1-1.2-1.01.11.1-1.0-1.11.1-0.8-0.8-1.0-0.80.8-0.6
Time >=10cm from walls, locomotor time 20.30.40.90.7-0.70.9-0.7-0.50.50.6-0.5-0.50.60.5-0.51.00.50.40.4-0.40.3
Bouts of movement, locomotor time 23.03.23.7-1.91.9-1.81.91.8-1.8-1.91.81.9-1.9-1.81.8-1.9-1.7-1.6-1.71.7-1.5
Total resting periods, locomotor time 23.53.74.6-2.02.0-1.92.01.9-1.8-2.01.92.1-2.0-2.02.0-2.1-1.8-1.6-1.81.8-1.6
Rest time, locomotor task time 20.10.20.30.2-0.2-0.1-0.3-0.50.40.3-0.4-0.30.40.5-0.5-0.20.40.40.5-0.50.5
Distance moved, locomotor task time 20.10.10.70.2-0.20.3-0.2-0.10.10.2-0.1-0.20.20.1-0.10.90.20.10.2-0.20.2
Vertical activity count, locomotor time 20.10.10.2-0.20.20.00.30.4-0.4-0.30.40.5-0.4-0.50.50.1-0.4-0.4-0.40.4-0.5
Light reinforcement 10.91.75.41.6-1.62.3-1.5-1.51.61.3-1.4-1.11.11.1-1.11.30.61.40.5-0.50.2
Light reinforcement 20.20.21.20.2-0.21.1-0.10.1-0.4-0.10.30.3-0.2-0.20.20.3-0.6-0.2-0.60.7-0.9
Bone: marrow area6.113.317.1-4.14.1-4.14.13.8-3.9-3.93.73.8-3.7-3.73.7-2.7-3.3-3.4-3.23.1-2.7
Bone: maximum diameter1.42.65.5-2.01.9-2.31.91.7-1.8-1.71.71.6-1.6-1.61.6-1.4-1.2-1.4-1.11.1-0.8
Bone: maximum force13.022.527.6-5.25.2-5.35.25.1-5.1-5.05.04.8-4.8-4.74.7-4.4-4.2-4.5-4.14.0-3.6
Bone: maximum moment14.725.330.5-5.55.5-5.45.45.4-5.4-5.35.35.1-5.1-5.05.0-4.7-4.5-4.7-4.44.4-3.9
Mean time between licks in bursts0.00.00.10.1-0.10.2-0.10.0-0.20.10.2-0.00.10.2-0.20.30.1-0.10.1-0.10.0
Mean num. licks in bursts0.60.71.5-0.70.7-0.30.71.1-1.1-0.71.20.8-0.8-0.80.8-0.4-0.9-1.0-0.80.9-0.9
Cd content in liver0.50.50.90.8-0.81.0-0.8-0.80.90.7-0.9-0.70.70.7-0.70.50.50.80.5-0.50.4
Co content in liver0.40.51.00.9-0.91.0-0.9-0.60.50.8-0.5-0.70.70.7-0.70.30.60.50.6-0.50.4
Cu content in liver0.20.20.9-0.60.6-1.00.60.4-0.3-0.50.30.5-0.4-0.30.3-0.8-0.2-0.3-0.20.2-0.0
Fe content in liver0.81.01.31.0-1.00.7-1.1-1.00.81.1-0.8-1.01.11.1-1.10.81.10.81.1-1.11.1
K content in liver0.10.10.50.1-0.1-0.4-0.2-0.20.10.3-0.1-0.20.40.4-0.40.10.50.20.6-0.60.7
Mg content in liver0.20.20.30.4-0.40.2-0.5-0.50.50.5-0.5-0.40.50.6-0.60.10.50.50.5-0.50.5
Mn content in liver0.10.10.3-0.40.4-0.40.40.4-0.4-0.40.40.4-0.3-0.30.3-0.5-0.3-0.3-0.30.3-0.2
Na content in liver0.20.30.40.5-0.50.2-0.5-0.50.50.5-0.5-0.50.60.6-0.60.30.60.40.6-0.60.6
Rb content in liver2.22.73.31.5-1.50.9-1.6-1.71.71.6-1.7-1.71.71.8-1.81.51.81.51.8-1.81.8
Se content in liver2.02.53.21.5-1.51.1-1.6-1.71.81.6-1.8-1.61.61.5-1.51.21.61.51.6-1.61.6
Sr content in liver0.00.00.1-0.10.1-0.30.1-0.00.1-0.1-0.10.1-0.0-0.10.1-0.00.0-0.00.0-0.00.1
Zn content in liver2.73.03.51.8-1.81.7-1.8-1.81.71.8-1.7-1.81.81.9-1.91.91.61.61.6-1.61.4
Bone: minimum diameter7.714.317.6-4.24.2-4.24.14.0-4.0-4.03.83.9-3.9-3.83.8-3.4-3.4-3.5-3.33.3-2.9
Time in familiar zone, hab. session 10.00.00.20.1-0.00.4-0.00.00.1-0.10.00.2-0.1-0.20.20.1-0.3-0.0-0.30.3-0.4
Time in novel zone, hab. session 10.00.00.2-0.20.2-0.50.20.1-0.1-0.10.10.0-0.1-0.00.0-0.30.1-0.10.1-0.10.2
Total zone transitions, hab. session 10.10.10.40.4-0.40.6-0.3-0.40.50.3-0.4-0.20.20.2-0.20.30.10.40.1-0.1-0.0
Total locomotion distance, hab. session 10.30.51.00.5-0.5-0.1-0.5-0.70.60.6-0.6-0.70.70.7-0.70.10.90.60.9-0.91.0
Locomotion velocity, hab. session 10.20.30.70.3-0.3-0.2-0.4-0.50.50.5-0.5-0.60.60.6-0.60.10.70.50.7-0.80.9
Time in familiar zone, hab. session 21.51.51.9-1.21.2-0.71.21.3-1.1-1.31.21.3-1.3-1.31.3-0.8-1.4-1.1-1.41.4-1.4
Time in novel zone, hab. session 21.71.72.51.2-1.20.6-1.2-1.41.31.3-1.3-1.41.41.4-1.40.91.51.21.5-1.51.6
Total zone transitions, hab. session 20.20.30.50.6-0.60.6-0.6-0.60.70.5-0.6-0.60.50.6-0.60.40.40.50.4-0.40.3
Total locomotion distance, hab. session 20.40.50.70.6-0.60.3-0.7-0.70.80.7-0.8-0.80.70.8-0.80.40.80.60.8-0.80.8
Locomotion velocity, hab. session 20.20.30.40.5-0.50.2-0.5-0.50.60.5-0.6-0.60.60.6-0.60.20.60.50.6-0.60.6
Novel to familiar place preference ratio1.31.32.5-1.31.3-1.41.31.1-1.1-1.21.11.1-1.2-1.11.1-1.6-1.0-0.9-1.00.9-0.8
Novelty place preference0.70.81.8-1.01.0-1.21.00.7-0.7-0.90.70.8-0.9-0.80.8-1.3-0.7-0.6-0.70.6-0.5
Time in novel zone, NPP test0.50.51.5-0.90.9-1.10.80.5-0.5-0.80.50.7-0.7-0.70.7-1.2-0.5-0.4-0.50.5-0.3
Total zone transitions, NPP test2.53.63.91.9-1.91.5-1.9-1.91.82.0-1.8-2.02.02.0-2.01.92.01.72.0-2.01.9
Total locomotion distance, NPP test3.34.55.12.1-2.11.6-2.2-2.22.22.2-2.2-2.32.22.3-2.31.92.21.92.2-2.22.1
Locomotion velocity, NPP test2.23.13.51.7-1.71.2-1.7-1.81.81.8-1.8-1.91.81.9-1.91.51.91.61.8-1.91.8
Intraocular pressure4.76.511.63.0-2.93.4-2.9-2.72.62.7-2.7-2.52.52.5-2.52.82.02.41.9-1.91.5
Delta distance traveled before/after self-admin0.20.20.3-0.40.4-0.20.50.3-0.1-0.50.20.4-0.5-0.50.5-0.5-0.5-0.2-0.50.5-0.5
Delta ambulatory time before/after self-admin0.10.10.2-0.20.30.10.30.10.0-0.30.10.3-0.3-0.30.3-0.3-0.4-0.0-0.50.4-0.4
Parametrial fat weight1.32.54.31.8-1.82.1-1.7-1.82.01.6-1.7-1.51.51.5-1.51.51.11.71.0-1.00.8
Pavlov. Cond. lever latency0.20.31.00.1-0.1-0.5-0.2-0.50.40.4-0.4-0.40.50.4-0.40.80.80.40.8-0.81.0
Pavlov. Cond. magazine entry latency1.01.22.3-0.90.9-0.21.01.1-1.1-1.11.11.1-1.2-1.11.1-0.9-1.4-1.0-1.41.4-1.5
Pavlov. Cond. change in total contacts1.41.52.8-0.90.9-0.11.01.2-1.2-1.11.21.2-1.2-1.21.2-1.2-1.5-1.0-1.51.5-1.7
Pavlov. Cond. index score0.81.02.0-0.70.70.00.81.0-0.9-0.90.90.9-1.0-0.90.9-1.1-1.2-0.8-1.31.3-1.4
Pavlov. Cond. latency score0.60.71.7-0.50.60.10.60.8-0.7-0.80.80.8-0.9-0.80.8-1.0-1.1-0.7-1.21.2-1.3
Pavlov. Cond. lever contacts0.20.20.90.1-0.10.80.00.3-0.2-0.20.30.3-0.3-0.30.3-0.6-0.7-0.3-0.70.8-1.0
Pavlov. Cond. magazine entry number0.40.41.00.4-0.4-0.2-0.5-0.60.70.6-0.7-0.60.70.6-0.60.30.90.60.9-0.91.0
Pavlov. Cond. intertrial magazine entries4.65.69.12.0-2.00.7-2.1-2.32.22.4-2.2-2.52.52.5-2.52.12.92.02.9-2.93.0
Pavlov. Cond. lever-magazine prob. diff.1.11.32.1-0.90.9-0.31.01.2-1.1-1.11.21.1-1.2-1.11.1-1.3-1.4-1.0-1.41.4-1.5
Pavlov. Cond. response bias0.30.41.0-0.30.30.30.40.6-0.6-0.50.60.6-0.6-0.60.6-0.5-0.8-0.5-0.90.9-1.0
Pavlov. Cond. lever latency1.01.42.4-0.90.9-0.31.01.2-1.4-1.11.51.1-1.1-1.11.1-1.3-1.3-1.1-1.31.3-1.4
Pavlov. Cond. magazine entry latency0.30.31.2-0.10.1-1.00.0-0.30.30.2-0.6-0.30.40.3-0.30.70.80.30.8-0.81.1
Pavlov. Cond. change in total contacts0.30.41.3-0.90.9-1.10.90.6-0.3-0.80.30.7-0.7-0.70.7-0.3-0.5-0.5-0.50.5-0.3
Pavlov. Cond. index score0.60.82.00.3-0.3-0.5-0.4-0.81.00.6-1.2-0.70.80.7-0.71.21.20.81.2-1.21.4
Pavlov. Cond. latency score0.60.81.90.3-0.3-0.5-0.4-0.81.00.6-1.2-0.70.80.7-0.71.21.10.71.1-1.21.4
Pavlov. Cond. lever contacts0.91.22.40.9-0.90.6-1.0-1.21.41.0-1.6-1.01.11.0-1.01.21.11.11.1-1.11.1
Pavlov. Cond. magazine entry number0.30.31.90.5-0.41.4-0.30.1-0.20.10.40.0-0.1-0.00.0-0.6-0.6-0.1-0.70.7-1.0
Pavlov. Cond. intertrial magazine entries1.92.56.72.0-2.02.6-1.9-1.61.61.7-1.4-1.61.51.6-1.61.01.01.40.9-0.90.6
Pavlov. Cond. lever-magazine prob. diff.0.30.41.4-0.0-0.0-0.8-0.1-0.50.70.3-0.9-0.40.50.4-0.40.80.90.50.9-0.91.2
Pavlov. Cond. response bias0.50.71.60.6-0.60.2-0.6-0.91.10.7-1.3-0.70.80.7-0.70.90.90.80.9-0.90.9
Time in closed arm before self-admin0.91.11.5-1.21.2-1.21.11.1-1.2-1.11.11.0-1.0-1.11.1-1.0-0.8-0.9-0.80.8-0.7
Time in closed arm after self-admin0.40.40.9-0.80.8-0.90.70.8-0.6-0.70.80.6-0.6-0.60.6-0.6-0.5-0.6-0.50.5-0.4
Time in open arm before self-admin0.20.20.9-0.40.4-0.90.40.7-0.9-0.31.00.2-0.2-0.10.1-0.30.0-0.70.0-0.10.2
Time in open arm after self-admin0.20.20.30.5-0.50.5-0.5-0.40.20.5-0.4-0.40.50.6-0.60.50.50.30.5-0.50.4
Bone: periosteal estimation8.517.523.7-4.74.7-4.94.64.4-4.5-4.44.34.3-4.2-4.24.2-3.5-3.6-3.9-3.53.5-3.0
Bone: periosteal perimeter8.213.717.2-4.24.1-4.14.13.8-3.7-4.03.73.9-3.8-3.83.8-3.4-3.4-3.2-3.33.2-2.8
Bone: post-yield work7.410.113.1-3.63.6-3.63.63.4-3.4-3.43.33.2-3.3-3.23.2-2.2-2.8-3.0-2.82.7-2.4
Progressive ratio test 1 active lever presses7.78.18.93.0-3.02.4-3.0-3.02.73.0-2.9-2.93.02.9-2.92.92.82.52.8-2.82.6
Progressive ratio test 1 breakpoint6.66.97.72.8-2.82.3-2.8-2.82.62.8-2.7-2.72.72.7-2.72.72.62.32.5-2.52.4
Progressive ratio test 1 inactive lever presses1.92.14.21.7-1.72.0-1.7-1.51.51.6-1.5-1.51.41.4-1.41.31.21.21.1-1.10.9
Progressive ratio test 2 active lever presses1.82.03.11.6-1.61.8-1.6-1.51.41.5-1.5-1.41.41.4-1.41.51.11.31.1-1.10.9
Progressive ratio test 2 breakpoint2.12.33.91.8-1.82.0-1.7-1.71.61.6-1.6-1.51.51.5-1.51.51.21.41.1-1.10.9
Progressive ratio test 2 inactive lever presses1.01.23.21.4-1.31.8-1.3-1.21.21.1-1.2-1.11.00.9-0.91.10.71.00.6-0.60.4
Incentive Sensitization - Responses0.30.30.7-0.40.40.10.50.4-0.4-0.50.40.5-0.6-0.70.7-0.5-0.8-0.4-0.80.8-0.8
Incentive Sensitization - Breakpoint0.20.20.6-0.30.30.20.40.3-0.3-0.50.30.4-0.5-0.60.6-0.5-0.7-0.3-0.70.7-0.8
Sum of active levers in priming session hrs 5-60.50.50.80.5-0.50.1-0.6-0.80.80.6-0.7-0.60.70.6-0.60.50.80.60.8-0.80.9
Progressive ratio0.91.01.50.9-0.90.4-1.0-1.00.81.0-1.0-1.11.11.2-1.20.91.20.81.2-1.21.2
Food seeking constrained by brief footshock1.61.92.71.3-1.30.8-1.4-1.31.01.5-1.1-1.51.51.5-1.51.41.61.01.6-1.61.6
Seeking ratio, punishment vs. effort0.10.10.2-0.30.3-0.00.30.3-0.3-0.30.50.4-0.3-0.40.4-0.2-0.4-0.3-0.40.4-0.4
Retroperitoneal fat weight1.03.44.21.8-1.91.6-1.9-1.92.01.9-1.7-1.91.91.9-1.92.01.81.61.8-1.81.7
Reaction time number correct1.01.42.4-1.51.5-1.51.41.2-1.1-1.31.21.3-1.2-1.11.1-0.8-1.0-1.0-0.90.9-0.7
Reaction time mean minus median5.67.411.63.0-3.03.4-2.9-3.03.22.8-3.1-2.72.62.7-2.72.62.12.72.0-2.01.6
Reaction time mean minus median AUC4.05.27.72.5-2.52.8-2.5-2.62.82.3-2.6-2.32.22.3-2.32.21.82.41.7-1.71.4
Reaction time num false alarms1.31.72.51.5-1.51.6-1.4-1.51.51.4-1.4-1.41.31.2-1.21.41.11.41.0-1.00.9
Reaction time num false alarms AUC1.52.03.21.6-1.61.8-1.6-1.71.61.5-1.5-1.51.41.3-1.31.31.11.51.1-1.00.9
Reaction time trials correct on left1.01.42.4-1.51.5-1.51.41.2-1.1-1.31.21.3-1.2-1.11.1-0.8-1.0-1.0-0.90.9-0.7
Reaction time trials on left0.81.11.9-1.31.3-1.41.21.1-0.9-1.21.11.1-1.1-1.01.0-0.7-0.9-0.9-0.80.8-0.6
Reaction time mean0.60.91.21.0-1.01.0-1.0-1.11.01.0-1.0-1.00.90.9-0.90.60.81.00.8-0.80.7
Reaction time mean AUC0.30.50.60.8-0.80.7-0.8-0.80.70.7-0.6-0.80.70.7-0.70.30.60.70.6-0.60.5
Median of all reaction times0.00.00.10.1-0.1-0.1-0.1-0.20.10.1-0.0-0.10.10.1-0.1-0.40.10.20.1-0.10.2
Reaction time omissions7.09.613.93.5-3.53.7-3.5-3.23.23.3-3.1-3.23.13.1-3.13.12.62.82.6-2.52.1
Reaction time false alarm rate1.62.23.91.8-1.82.0-1.7-1.71.61.6-1.6-1.61.51.4-1.41.11.21.51.1-1.10.9
Reaction time premature initiation rate3.95.29.92.7-2.73.1-2.7-2.01.82.5-2.0-2.52.32.4-2.42.51.91.71.8-1.81.4
Reaction time premature initiations1.62.34.71.8-1.82.2-1.7-1.21.11.6-1.2-1.61.51.7-1.71.91.21.01.2-1.20.9
Std. dev. reaction times4.76.68.82.9-2.83.0-2.8-2.92.92.7-2.8-2.62.52.6-2.62.42.12.62.0-2.01.8
Reaction time trials completed0.81.11.9-1.31.3-1.41.21.1-0.9-1.21.11.1-1.1-1.01.0-0.7-0.9-0.9-0.80.8-0.6
Reaction time trials AUC1.31.83.1-1.71.7-1.71.61.4-1.2-1.51.41.5-1.4-1.31.3-1.0-1.1-1.2-1.11.1-0.9
Run reversals in cocaine runway, females0.60.51.0-0.60.6-0.20.60.8-0.6-0.70.60.8-0.8-0.70.7-0.8-0.9-0.7-0.90.9-1.0
Run reversals in cocaine runway, males0.80.81.71.0-1.01.2-1.0-1.11.30.9-1.3-0.70.80.8-0.80.40.61.10.5-0.50.4
Latency to leave start box in cocaine runway0.00.00.10.0-0.00.2-0.00.1-0.10.00.3-0.2-0.00.1-0.10.3-0.0-0.0-0.10.1-0.1
Latency to leave start box in cocaine runway, F1.41.52.21.4-1.41.5-1.4-1.21.11.3-0.8-1.41.31.3-1.31.41.11.01.1-1.10.9
Latency to leave start box in cocaine runway, M2.02.02.4-1.61.6-1.41.61.4-1.2-1.51.21.4-1.5-1.51.5-1.3-1.4-1.1-1.41.4-1.2
Std. dev. time between licks in bursts1.21.42.41.3-1.31.4-1.3-1.20.91.3-1.1-1.11.21.3-1.31.61.01.01.0-1.00.9
Total sessions with >9 infusions1.31.41.91.4-1.41.3-1.3-1.31.31.3-1.3-1.31.21.1-1.11.21.01.11.0-1.00.9
Short access day 1 total inactive lever presses1.11.21.91.3-1.31.4-1.3-1.21.21.2-1.2-1.21.11.1-1.11.20.90.90.9-0.90.7
Short access day 10 total inactive lever presses0.10.10.2-0.10.10.20.20.10.1-0.20.10.3-0.3-0.20.2-0.3-0.4-0.0-0.40.4-0.5
Short access day 1 total infusions0.50.60.80.7-0.70.5-0.8-0.70.60.8-0.7-0.90.80.7-0.70.90.80.50.8-0.80.8
Short access day 10 total infusions2.42.73.01.7-1.71.3-1.7-1.71.61.7-1.7-1.71.71.6-1.61.61.71.41.7-1.71.6
Short access total infusions1.51.72.01.4-1.41.1-1.4-1.31.31.4-1.3-1.41.41.3-1.31.41.31.01.3-1.31.2
Short access day 1 locomotion0.20.20.30.5-0.50.4-0.5-0.50.50.5-0.5-0.50.50.4-0.40.30.50.40.4-0.40.4
Short access day 10 total locomotion0.10.20.20.4-0.40.4-0.4-0.40.30.4-0.4-0.50.40.4-0.40.50.40.40.4-0.40.4
Short access total locomotion0.50.50.60.8-0.80.8-0.7-0.70.80.7-0.7-0.70.70.7-0.70.70.60.60.6-0.60.6
One hour access (0.3 mA shock)0.10.10.60.1-0.10.6-0.00.3-0.1-0.10.20.2-0.3-0.20.2-0.4-0.5-0.3-0.60.6-0.8
Compulsive drug intake1.71.72.4-1.41.4-1.21.41.3-1.2-1.41.31.3-1.3-1.31.3-1.5-1.3-1.2-1.31.3-1.2
One hour access (shock baseline)0.10.10.40.2-0.20.7-0.10.1-0.00.00.00.1-0.1-0.10.10.0-0.3-0.1-0.30.3-0.5
Social response proportion0.10.10.20.4-0.40.5-0.3-0.20.30.3-0.1-0.20.30.3-0.30.10.20.10.2-0.20.1
Social responses5.16.511.32.9-2.93.4-2.8-2.93.02.6-2.6-2.62.52.5-2.52.22.02.51.9-1.91.5
Social time0.30.41.0-0.50.5-0.20.50.7-0.6-0.60.90.5-0.6-0.60.6-1.0-0.7-0.6-0.70.7-0.7
Soleus weight1.02.83.3-1.71.7-1.51.71.7-1.8-1.71.81.7-1.7-1.81.8-1.6-1.7-1.5-1.61.6-1.5
Bone: stiffness16.826.631.5-5.65.6-5.35.65.5-5.5-5.45.55.3-5.3-5.25.2-4.5-4.8-4.8-4.74.6-4.2
Tibialis anterior weight2.99.912.3-2.92.9-1.83.03.4-3.3-3.13.23.2-3.3-3.23.2-3.2-3.5-2.9-3.43.5-3.5
Time to tail flick, vehicle, before self-admin0.70.70.90.9-0.90.8-0.9-0.70.80.9-1.0-0.90.90.8-0.80.80.70.50.7-0.70.6
Time to tail flick, vehicle, after self-admin0.60.61.1-0.70.7-0.60.71.0-1.0-0.80.90.7-0.8-0.80.8-0.7-0.7-0.9-0.70.7-0.7
Time to tail flick, test, before self-admin0.10.10.10.3-0.40.4-0.3-0.10.00.3-0.2-0.30.30.3-0.30.30.20.00.3-0.30.1
Time to tail flick, test, after self-admin0.80.91.2-0.80.8-0.60.91.0-1.1-0.91.11.0-0.9-1.01.0-0.9-1.0-1.0-0.90.9-1.0
Delta time to tail flick, vehicle, before/after SA0.70.71.0-0.90.9-0.60.90.9-0.9-0.91.00.9-0.9-0.80.8-0.8-0.8-0.7-0.80.8-0.8
Delta time to tail flick, test, before/after SA0.80.71.1-0.80.8-0.30.80.7-0.5-0.90.60.9-0.9-0.90.9-0.8-1.0-0.5-1.01.0-1.0
Tibia length3.911.018.7-3.93.9-4.33.83.4-3.5-3.53.53.4-3.3-3.43.4-2.7-2.7-3.0-2.62.5-2.0
Ambulatory time before self-admin4.04.14.82.2-2.22.0-2.2-2.11.92.1-1.9-2.12.12.1-2.12.11.91.81.9-1.91.7
Ambulatory time after self-admin1.81.93.01.5-1.51.6-1.4-1.71.71.4-1.6-1.31.31.3-1.31.21.21.51.1-1.11.0
Bone: tissue strength2.01.92.5-1.41.4-1.31.41.5-1.6-1.41.61.4-1.4-1.41.4-1.3-1.3-1.4-1.21.2-1.1
Total heroin consumption1.11.32.1-1.31.3-1.41.31.4-1.4-1.21.41.0-1.1-1.11.1-0.8-0.8-1.2-0.80.8-0.6
Bone: trabecular number3.65.710.2-2.82.8-3.22.72.4-2.5-2.52.52.4-2.4-2.42.4-1.9-1.9-2.2-1.81.7-1.4
Bone: trabecular spacing1.31.73.11.5-1.51.8-1.4-1.51.71.3-1.6-1.21.21.2-1.20.70.91.40.8-0.80.6
Bone: trabecular thickness0.70.81.9-0.50.50.20.60.9-1.1-0.81.00.8-0.9-0.80.8-1.1-1.2-0.8-1.21.2-1.4
Bone: trabecular tissue density0.91.22.8-0.70.70.10.80.9-0.7-1.00.81.1-1.2-1.11.1-1.5-1.5-0.8-1.51.5-1.7
Water consumed over 24 hours0.10.10.30.2-0.2-0.1-0.2-0.30.20.3-0.3-0.40.30.4-0.40.20.40.20.4-0.50.5
Number of responses in last shaping day0.40.40.8-0.50.5-0.10.60.5-0.4-0.60.50.7-0.7-0.70.7-0.6-0.8-0.5-0.90.9-0.9