Hub : Genes

Armc6

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA mRNA stability Armc6 0.08 0.05 3.6e-03 0.03 0.02 0 0.03 1.2e-02 4.5e-02 2.2e-01 6.8e-03
2 Liver gene expression Armc6 0.03 0.02 1.7e-03 0.02 0.01 0.01 0.01 3.6e-03 2.2e-02 2.5e-02 1.0e-02
3 Adipose mRNA stability Armc6 0.07 0.04 1.3e-06 0.04 0.05 0.05 0.04 3.7e-05 7.0e-06 5.6e-06 1.4e-05
4 Brain mRNA stability Armc6 0.46 0.12 0.0e+00 0.3 0.3 0.33 0.32 2.6e-28 1.5e-28 2.9e-31 3.1e-30
5 PL mRNA stability Armc6 0.28 0.09 0.0e+00 0.2 0.2 0.19 0.2 3.0e-21 6.6e-22 1.4e-20 1.7e-21
6 NAcc mRNA stability Armc6 0.16 0.08 8.2e-08 0.06 0.05 0.05 0.05 6.6e-09 3.7e-08 5.6e-08 2.5e-08
7 pVTA mRNA stability Armc6 0.1 0.05 2.5e-04 0.04 0.05 0.05 0.05 3.1e-04 8.2e-05 9.9e-05 5.2e-05
8 IL mRNA stability Armc6 0.47 0.14 1.0e-07 0.26 0.21 0.23 0.24 6.9e-07 1.0e-05 2.5e-06 1.7e-06
9 OFC mRNA stability Armc6 0.31 0.15 5.3e-04 0.2 0.09 0.11 0.16 1.3e-05 3.3e-03 1.3e-03 1.1e-04
10 Adipose gene expression Armc6 0.06 0.03 1.5e-05 0.02 0.05 0.04 0.04 8.7e-04 3.2e-06 1.4e-05 3.3e-05
11 LHb mRNA stability Armc6 0.21 0.12 7.1e-03 0.03 0.03 0 0.03 6.6e-02 6.0e-02 2.6e-01 7.7e-02
12 PL intron excision ratio chr16_19230869_19234614 0.03 0.02 8.9e-03 0.03 0.01 0.02 0.02 7.7e-04 1.2e-02 2.1e-03 3.5e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density5.08.713.53.20.41.93.73.43.53.53.33.30.62.83.2
Area under the delay curve0.20.20.8-0.2-0.50.9-0.4-0.4-0.1-0.3-0.4-0.30.60.2-0.8
BMI with tail1.03.59.32.02.32.81.71.61.21.11.01.33.01.91.2
BMI without tail1.65.013.12.43.03.21.72.01.41.51.31.53.62.21.3
Body weight4.519.732.35.04.75.74.24.53.93.83.54.15.14.83.6
Weight adjusted by age0.91.33.11.41.70.91.51.31.00.80.81.11.30.90.6
Bone surface2.54.57.12.50.31.72.52.42.72.42.22.40.92.12.1
Bone volume4.07.210.33.20.82.13.23.13.23.02.83.01.22.62.7
Breakpoint value in progressive ratio session0.10.20.80.00.20.1-0.4-0.4-0.2-0.9-0.4-0.20.4-0.5-0.3
Number of licking bursts0.10.20.4-0.5-0.30.6-0.3-0.6-0.3-0.3-0.5-0.40.10.3-0.3
Context. condit. distance diff. score0.30.31.4-0.8-0.2-0.7-0.6-0.4-0.50.0-0.3-0.5-1.20.00.1
Locomotion velocity, session 11.51.62.6-1.4-0.7-0.1-1.5-1.4-1.6-1.3-1.6-1.60.6-0.9-1.3
Locomotion distance, session 10.70.93.3-1.1-1.8-0.6-0.9-0.9-0.8-0.5-0.9-0.8-0.7-0.7-0.8
Locomotion velocity, session 20.70.83.4-0.31.11.1-0.6-0.4-0.7-0.6-0.9-0.81.80.3-0.6
Locomotion distance, session 20.71.04.1-1.0-2.0-0.9-0.8-1.0-0.7-0.7-0.7-0.7-0.9-1.0-0.7
Locomotion velocity, session 32.32.74.0-2.0-0.5-1.6-1.8-1.9-1.8-1.7-1.8-1.9-1.2-1.5-1.3
Locomotion distance, session 30.30.41.30.1-0.9-0.70.30.40.50.80.50.4-1.10.10.3
Stereotopy head waving bouts, day 31.01.22.9-1.6-0.7-0.7-1.2-1.5-1.0-1.0-1.0-0.9-1.7-0.5-0.1
Stereotopy head waving duration, day 30.81.02.0-1.4-0.1-0.3-1.4-1.4-1.0-1.0-1.2-1.0-0.9-0.3-0.4
Locomotion velocity, session 71.61.72.5-1.3-1.4-1.3-1.5-1.3-1.2-1.2-1.1-1.3-1.0-1.5-1.6
Locomotion distance, session 70.40.62.1-0.7-1.4-0.7-0.7-0.8-0.5-0.6-0.5-0.5-0.7-0.9-0.5
Stereotopy head waving bouts, day 70.10.10.5-0.00.2-0.1-0.10.00.20.20.30.2-0.70.30.1
Stereotopy head waving duration, day 70.10.10.6-0.30.8-0.0-0.6-0.3-0.3-0.3-0.2-0.3-0.30.1-0.3
Locomotion velocity, session 85.06.09.6-3.0-1.5-1.9-3.1-2.8-2.6-2.5-2.8-2.9-1.3-2.1-2.1
Locomotion distance, session 80.40.52.1-0.9-1.4-0.6-0.8-0.7-0.6-0.2-0.5-0.7-0.8-0.4-0.1
Degree of sensitization distance0.70.71.7-0.9-0.4-0.3-0.8-1.1-0.9-1.3-1.0-0.90.1-0.9-0.6
Degree of sensitization stereotypy0.40.40.80.70.50.30.50.80.70.90.80.8-0.20.80.2
Conditioned locomotion0.20.30.50.4-0.00.40.70.30.50.50.70.7-0.30.40.7
Cocaine response after cond. corrected0.20.21.20.00.4-0.50.30.30.10.40.50.5-1.10.10.5
Cocaine response after cond. not corrected0.50.61.5-0.9-0.1-1.0-0.8-0.8-0.8-0.6-0.5-0.6-1.2-0.7-0.4
Cocaine response before conditioning2.63.14.8-1.7-1.2-0.8-2.1-2.0-1.8-2.1-2.1-2.20.2-1.6-2.1
Saline control response0.10.10.5-0.3-0.7-0.7-0.30.1-0.20.1-0.4-0.1-0.3-0.2-0.0
Bone: connectivity density4.06.39.72.70.31.83.03.02.83.12.72.71.02.52.8
Bone: cortical apparent density0.10.10.70.1-0.8-0.10.60.0-0.2-0.1-0.1-0.00.4-0.4-0.5
Bone: cortical area7.010.816.54.13.02.93.43.63.73.03.53.32.23.03.3
Bone: cortical porosity0.20.20.9-0.0-0.30.4-0.4-0.3-0.2-0.4-0.2-0.30.6-0.2-1.0
Bone: cortical porosity0.10.10.50.1-0.30.5-0.3-0.2-0.0-0.10.0-0.10.60.0-0.7
Bone: cortical thickness5.99.813.63.72.42.53.63.43.63.13.63.41.32.93.2
Bone: cortical thickness6.07.011.42.71.11.73.12.73.12.93.33.0-0.52.63.4
Bone: cortical tissue density0.10.20.9-0.1-0.9-0.20.4-0.1-0.4-0.2-0.2-0.20.3-0.6-0.7
Condit. Reinf. active minus inactive responses1.51.72.71.30.41.21.31.31.61.61.51.50.11.61.1
Condit. Reinf. active-inactive response ratio3.23.45.71.90.21.02.02.02.42.32.22.2-0.41.81.8
Condit. Reinf. active responses1.01.22.41.00.71.50.81.11.31.31.21.10.51.50.8
Condit. Reinf. inactive responses0.20.31.6-0.00.80.8-0.5-0.0-0.4-0.2-0.4-0.41.30.3-0.1
Incentive salience index mean1.11.33.41.10.61.90.91.01.31.11.11.11.01.50.7
Condit. Reinf. lever presses0.71.04.50.80.72.10.40.40.60.50.60.61.71.20.6
Condit. Reinf. active minus inactive responses0.10.20.8-0.2-0.6-0.9-0.2-0.3-0.1-0.2-0.4-0.3-0.6-0.6-0.1
Condit. Reinf. active-inactive response ratio0.20.20.60.50.70.30.80.40.40.30.30.30.30.40.6
Condit. Reinf. active responses1.62.23.3-1.5-1.4-1.8-1.6-1.5-1.3-1.4-1.7-1.6-1.0-1.6-1.3
Condit. Reinf. inactive responses4.76.18.5-2.6-2.0-2.6-2.9-2.6-2.5-2.5-2.7-2.7-1.3-2.6-2.4
Condit. Reinf. lever presses0.81.12.2-0.80.1-0.4-1.5-1.2-1.1-1.4-1.4-1.30.5-0.9-1.0
Condit. Reinf. lever reinforcers received0.91.21.8-1.0-0.8-1.3-1.3-1.1-1.0-1.1-1.3-1.2-0.5-1.3-0.9
Conditioned reinforcement - actives1.01.63.31.31.71.11.81.41.01.30.91.01.31.31.0
Conditioned reinforcement - inactives5.27.713.52.93.72.43.03.12.42.72.62.52.12.92.6
Conditioned locomotion0.81.02.30.81.51.11.51.00.51.00.60.61.11.10.9
Patch foraging indifference point 0 sec0.81.55.50.82.12.30.10.10.4-0.10.0-0.12.31.10.7
Patch foraging indifference point AUC0.60.92.2-0.8-0.30.5-1.2-1.1-1.2-1.5-0.8-0.80.8-0.8-0.9
Delay disc. indifference point, 0s delay3.03.35.0-2.2-2.0-0.6-1.9-2.2-2.0-1.9-2.0-1.9-0.7-1.4-2.0
Delay disc. indifference point, 16s delay0.80.91.6-1.0-0.9-0.1-1.0-1.2-0.9-1.0-1.3-1.20.1-0.7-1.1
Delay disc. indifference point, 2s delay0.30.31.6-0.5-1.30.4-0.6-0.6-0.2-0.5-0.4-0.2-0.2-0.2-0.9
Delay disc. indifference point, 24s delay0.70.71.5-0.70.50.8-0.9-0.7-0.9-0.6-1.1-1.11.00.1-1.2
Delay disc. indifference point, 4s delay0.10.10.4-0.2-0.50.6-0.2-0.1-0.0-0.1-0.3-0.10.60.1-0.6
Delay disc. indifference point, 8s delay0.30.31.3-0.00.31.2-0.5-0.2-0.2-0.3-0.3-0.31.00.3-0.7
Indifference point function ln k1.12.03.61.41.11.01.71.61.41.91.41.20.61.61.5
Indifference point function log k1.12.03.61.41.11.01.71.61.41.91.41.20.61.61.5
Patch foraging total patch changes 0 sec1.32.58.41.22.62.90.50.50.70.20.30.22.81.61.1
Patch foraging total patch changes 12 sec0.60.81.3-0.50.90.9-1.1-1.0-0.8-1.1-0.9-0.91.1-0.1-0.8
Patch foraging total patch changes 18 sec0.71.13.3-0.8-0.0-0.1-1.1-1.5-1.0-1.8-1.2-1.10.1-1.2-0.8
Patch foraging total patch changes 24 sec0.10.20.70.30.60.80.1-0.10.4-0.40.10.10.50.30.5
Patch foraging total patch changes 6 sec0.91.33.1-0.51.31.4-1.0-1.1-1.0-1.4-1.3-1.21.80.1-0.6
Patch foraging time to switch 0 sec1.12.23.5-1.5-1.5-1.6-1.7-1.4-1.3-1.4-1.6-1.4-1.0-1.6-1.9
Patch foraging water rate 0 sec0.81.75.41.21.32.31.00.80.91.01.10.81.71.51.4
Patch foraging water rate 12 sec1.12.23.51.70.51.61.91.51.71.51.41.31.11.61.6
Patch foraging water rate 18 sec0.60.92.00.9-0.61.41.20.71.01.00.80.70.90.90.5
Patch foraging water rate 24 sec2.13.04.51.80.22.01.91.81.92.11.81.51.31.91.6
Patch foraging water rate 6 sec1.62.33.61.61.41.91.71.41.31.51.41.21.41.71.5
Seeking ratio, delayed vs. immediate footshock2.02.44.5-2.0-1.3-1.0-1.8-1.5-2.1-1.3-1.7-1.9-0.2-1.2-1.6
Distance traveled before self-admin0.40.51.3-0.31.20.7-0.8-0.3-0.7-0.6-0.7-0.81.10.1-0.7
Distance traveled after self-admin0.30.31.80.41.40.8-0.30.3-0.10.1-0.1-0.21.00.50.1
Extensor digitorum longus weight0.10.30.9-0.21.00.8-0.4-0.4-0.4-0.4-0.3-0.50.80.30.0
Bone: elastic displacement0.10.10.7-0.2-0.8-0.3-0.20.0-0.00.3-0.1-0.1-0.4-0.0-0.4
Bone: elastic work1.41.82.51.61.31.41.31.51.41.41.31.31.21.40.9
Bone: endosteal estimation0.10.31.70.40.51.0-0.30.10.1-0.1-0.1-0.11.30.4-0.0
Bone: endosteal perimeter0.71.53.41.51.81.20.91.21.30.80.90.91.31.11.2
Epididymis fat weight1.03.58.92.31.22.31.82.11.51.61.21.63.01.71.3
Delta time in closed arm before/after self-admin0.20.21.30.00.11.1-0.0-0.2-0.2-0.00.0-0.20.80.3-0.3
Delta time in open arm before/after self-admin0.40.40.9-0.4-0.8-1.0-0.6-0.5-0.3-0.6-0.5-0.3-0.6-0.8-0.4
Diff in mean of infusions in LGA sessions1.21.42.8-0.61.30.4-0.9-1.0-1.3-1.7-1.6-1.31.5-0.6-1.3
Delay discount exponential model param0.10.20.9-0.00.2-1.00.20.1-0.2-0.00.10.0-0.6-0.40.5
Extinction: sum of active levers before priming0.10.10.80.2-0.90.3-0.10.00.3-0.00.10.10.3-0.20.1
Active lever presses in extinction session 60.60.61.1-0.7-0.5-0.8-1.1-0.7-0.7-0.8-1.0-0.7-0.4-0.7-1.0
Bone: final force6.09.615.73.73.44.02.82.93.02.32.92.83.23.22.7
Bone: final moment5.89.314.73.63.33.82.72.93.02.42.92.83.13.22.6
Food consumed during 24 hour testing period0.10.11.20.1-1.10.1-0.0-0.00.30.20.20.1-0.3-0.00.2
Glucose0.40.73.00.71.41.30.30.30.2-0.20.30.21.70.50.4
Heart weight1.52.44.61.41.20.71.71.81.72.21.61.8-0.41.91.3
Delay discount hyperbolic model param0.20.21.00.00.2-1.00.30.1-0.10.10.20.0-0.6-0.40.6
Intermittent access intake day 1-15 change0.91.93.21.60.50.01.51.71.81.61.61.7-0.20.91.5
Intermittent access intake escalation0.91.93.21.50.2-0.11.41.71.81.81.71.8-0.30.91.5
Intermittent access intake escalation 21.01.22.11.30.70.61.01.51.21.31.11.20.80.90.9
Intermitt. access day 1 inactive lever presses0.00.20.60.20.7-0.80.60.50.10.40.30.3-0.3-0.0-0.2
Intermitt. access day 15 inactive lever presses0.10.21.2-0.20.3-1.10.10.1-0.10.1-0.00.0-1.0-0.2-0.3
Intermitt. access escalation Index0.10.20.6-0.6-0.80.0-0.7-0.5-0.4-0.2-0.4-0.4-0.3-0.1-0.3
Intermittent access day 1 total infusions0.30.42.1-0.21.40.8-0.1-0.3-0.7-0.5-0.5-0.50.90.2-0.3
Intermittent access day 15 total infusions0.91.42.21.30.80.61.21.41.21.51.41.40.31.01.3
Intermittent access terminal intake (last 3 days)0.81.01.31.10.90.90.91.11.01.11.11.10.60.91.1
Intermittent access total infusions0.81.02.31.11.51.10.91.00.70.80.90.81.00.91.0
Intermittent access day 1 locomotion0.70.83.00.71.71.51.00.50.00.20.30.11.60.70.4
Intermittent access day 15 total locomotion0.50.91.61.10.70.91.31.00.90.91.11.00.60.81.1
Intermittent access total locomotion1.11.32.91.21.71.51.41.10.70.80.80.81.41.01.0
Intermittent access standard deviation0.10.20.60.40.80.30.40.60.10.70.30.30.50.60.3
Left kidney weight0.10.73.70.41.41.30.0-0.0-0.2-0.5-0.1-0.21.90.20.3
Right kidney weight0.52.411.61.62.22.30.81.10.40.30.50.53.40.90.8
Cocaine induced anxiety0.60.92.0-0.51.40.1-0.5-0.8-1.0-1.3-1.2-1.00.7-0.5-1.2
Post-drug Anxiety0.80.91.9-0.90.2-0.5-0.9-1.0-1.1-1.2-1.1-1.1-0.0-0.8-1.4
Baseline Anxiety0.50.63.5-0.6-1.9-0.8-0.9-0.5-0.10.10.1-0.2-1.0-0.5-0.0
Tail length0.62.24.91.61.82.10.81.51.01.31.01.02.21.61.0
Length with tail1.87.811.33.32.93.42.42.92.62.52.52.63.02.92.3
Length without tail2.78.611.73.42.22.53.13.23.22.93.33.41.32.73.3
Times rat made contact with spout0.10.10.60.1-0.50.80.60.00.00.20.30.30.30.3-0.1
Lifetime Intake1.31.64.11.32.01.41.21.20.91.01.01.01.31.31.1
Liver weight, left0.10.21.00.2-1.0-0.5-0.00.00.10.00.00.1-0.4-0.6-0.1
Liver weight, right1.11.95.31.81.21.51.41.50.90.90.91.22.30.91.2
Locomotor activity0.71.01.81.2-0.61.20.81.11.01.31.01.00.91.00.9
Locomotor testing distance0.40.72.00.7-1.00.40.60.90.91.40.80.7-0.10.80.5
Locomotor testing rearing0.10.21.20.0-1.10.4-0.20.10.10.5-0.1-0.20.50.2-0.3
Locomotion in novel chamber0.50.62.30.80.11.50.60.60.60.50.60.61.00.80.6
Locomotion in novel chamber post-restriction3.25.38.42.4-0.32.02.42.42.92.52.62.80.72.12.6
Fecal boli incidents, locomotor time 10.10.10.50.2-0.60.60.60.20.30.00.30.20.70.00.1
Change in fecal boli incidents, locomotor task2.02.03.3-1.6-0.2-0.8-1.8-1.8-1.7-1.6-1.6-1.6-0.6-1.2-1.5
Time >=10cm from walls, locomotor time 10.20.20.6-0.20.00.2-0.2-0.6-0.6-0.8-0.3-0.50.5-0.7-0.3
Bouts of movement, locomotor time 10.10.20.5-0.1-0.4-0.1-0.3-0.2-0.4-0.3-0.6-0.30.4-0.4-0.7
Total resting periods, locomotor time 10.30.30.7-0.3-0.8-0.4-0.4-0.4-0.5-0.5-0.7-0.40.1-0.6-0.8
Rest time, locomotor task time 10.50.61.5-0.70.1-0.2-1.2-0.7-0.7-0.8-1.1-0.8-0.0-0.2-1.2
Distance moved, locomotor task time 10.10.20.4-0.5-0.1-0.5-0.4-0.5-0.5-0.5-0.2-0.5-0.3-0.6-0.1
Vertical activity count, locomotor time 10.00.10.20.2-0.3-0.20.20.30.10.30.40.20.1-0.00.5
Time >=10cm from walls, locomotor time 20.40.62.7-0.6-1.3-1.2-0.1-0.4-0.20.00.2-0.2-1.6-0.60.1
Bouts of movement, locomotor time 20.20.40.7-0.7-0.1-0.6-0.8-0.7-0.6-0.8-0.5-0.6-0.5-0.6-0.3
Total resting periods, locomotor time 20.20.30.8-0.60.2-0.4-0.7-0.7-0.5-0.9-0.5-0.5-0.4-0.5-0.3
Rest time, locomotor task time 20.20.31.50.11.20.7-0.6-0.1-0.2-0.2-0.3-0.10.70.4-0.5
Distance moved, locomotor task time 20.30.31.6-0.2-0.7-1.30.40.10.10.10.30.0-1.0-0.50.5
Vertical activity count, locomotor time 20.50.71.70.3-0.5-1.20.80.70.60.81.00.7-1.30.10.9
Light reinforcement 10.10.30.6-0.3-0.10.4-0.3-0.6-0.5-0.8-0.7-0.60.7-0.2-0.2
Light reinforcement 20.60.92.1-0.80.50.1-1.0-1.1-1.2-1.5-1.1-1.00.7-0.7-0.7
Bone: marrow area0.10.31.60.30.41.0-0.30.00.1-0.1-0.2-0.11.30.4-0.0
Bone: maximum diameter2.44.46.42.52.51.92.02.12.41.72.12.01.42.02.4
Bone: maximum force6.311.216.24.03.24.03.23.33.42.73.23.23.33.42.9
Bone: maximum moment5.710.114.83.83.03.73.03.13.32.63.13.13.03.22.8
Mean time between licks in bursts0.81.94.71.41.92.01.01.30.81.00.60.92.21.71.0
Mean num. licks in bursts0.60.91.71.10.10.11.31.21.01.11.31.2-0.00.41.0
Cd content in liver6.57.211.03.01.41.82.63.13.23.23.23.30.32.72.7
Co content in liver0.00.00.20.0-0.1-0.1-0.1-0.10.2-0.1-0.00.1-0.4-0.0-0.5
Cu content in liver0.30.41.9-0.6-1.4-0.60.1-0.4-0.1-0.0-0.0-0.1-1.3-0.30.1
Fe content in liver0.50.61.4-0.8-1.0-1.2-0.6-0.7-0.8-0.7-0.6-0.6-0.9-1.1-0.1
K content in liver2.32.23.5-1.9-1.3-1.4-1.6-1.8-1.3-1.5-1.5-1.6-1.4-1.3-0.8
Mg content in liver0.20.20.6-0.6-0.2-0.6-0.6-0.4-0.3-0.3-0.3-0.3-0.7-0.3-0.1
Mn content in liver0.10.10.6-0.30.3-0.6-0.80.0-0.10.1-0.1-0.2-0.4-0.1-0.2
Na content in liver2.02.24.9-1.7-2.2-1.2-1.3-1.5-1.5-1.3-1.5-1.6-0.7-1.4-1.1
Rb content in liver1.92.36.11.11.80.61.61.51.41.51.51.6-0.41.52.5
Se content in liver0.20.31.3-0.4-0.6-1.0-0.1-0.2-0.0-0.3-0.0-0.1-1.1-0.60.3
Sr content in liver0.10.10.30.1-0.5-0.3-0.00.2-0.1-0.0-0.3-0.20.3-0.4-0.4
Zn content in liver0.20.20.4-0.30.1-0.6-0.6-0.4-0.5-0.5-0.6-0.5-0.1-0.6-0.4
Bone: minimum diameter2.03.76.12.51.82.11.72.01.91.51.71.62.51.71.5
Time in familiar zone, hab. session 10.20.21.00.40.30.50.60.40.00.30.20.21.00.30.5
Time in novel zone, hab. session 10.30.30.80.3-0.10.20.00.40.60.90.50.5-0.80.80.2
Total zone transitions, hab. session 10.10.21.1-0.3-1.00.3-0.5-0.4-0.3-0.2-0.3-0.40.4-0.2-0.5
Total locomotion distance, hab. session 10.20.32.6-0.2-1.60.1-0.3-0.10.10.1-0.1-0.10.2-0.1-0.5
Locomotion velocity, hab. session 10.30.52.4-0.6-1.6-0.1-0.7-0.6-0.4-0.4-0.6-0.60.3-0.5-0.9
Time in familiar zone, hab. session 20.10.10.6-0.10.3-0.30.10.2-0.30.3-0.1-0.20.30.10.8
Time in novel zone, hab. session 20.30.30.60.6-0.10.20.50.50.80.50.70.7-0.40.3-0.1
Total zone transitions, hab. session 20.10.10.3-0.1-0.4-0.40.1-0.10.10.00.20.0-0.6-0.30.0
Total locomotion distance, hab. session 20.40.50.90.5-0.8-0.20.80.70.90.90.90.8-0.80.40.6
Locomotion velocity, hab. session 20.20.30.90.2-0.9-0.20.50.40.60.60.60.5-0.60.20.2
Novel to familiar place preference ratio0.50.50.91.00.40.80.70.80.70.60.90.80.70.50.4
Novelty place preference0.20.30.50.70.30.50.50.60.50.40.70.60.50.40.2
Time in novel zone, NPP test0.20.20.40.60.00.40.50.50.40.40.60.50.30.20.1
Total zone transitions, NPP test0.20.32.2-0.4-1.50.1-0.3-0.5-0.1-0.1-0.2-0.1-0.4-0.2-0.4
Total locomotion distance, NPP test0.30.43.8-0.4-2.0-0.0-0.2-0.20.20.3-0.00.1-0.70.0-0.8
Locomotion velocity, NPP test0.40.53.6-0.6-1.9-0.1-0.5-0.4-0.0-0.1-0.4-0.1-0.5-0.2-1.2
Intraocular pressure0.81.12.51.01.60.51.01.31.01.11.01.10.21.20.7
Delta distance traveled before/after self-admin0.40.40.80.90.90.60.60.70.60.40.50.50.80.50.5
Delta ambulatory time before/after self-admin0.20.20.50.60.40.10.70.40.50.20.50.50.10.10.5
Parametrial fat weight1.22.910.61.53.12.40.81.20.50.60.60.63.31.50.7
Pavlov. Cond. lever latency0.20.21.4-0.20.2-1.2-0.30.1-0.30.0-0.1-0.3-0.9-0.4-0.2
Pavlov. Cond. magazine entry latency0.30.31.20.60.31.10.70.30.50.30.30.31.00.60.1
Pavlov. Cond. change in total contacts0.80.84.10.70.82.00.60.20.60.30.50.51.41.20.3
Pavlov. Cond. index score0.20.21.20.1-0.21.10.1-0.30.1-0.2-0.2-0.11.00.3-0.4
Pavlov. Cond. latency score0.20.30.9-0.2-0.41.0-0.2-0.6-0.2-0.5-0.5-0.30.80.1-0.7
Pavlov. Cond. lever contacts0.20.31.40.20.11.20.1-0.20.1-0.2-0.10.01.20.3-0.3
Pavlov. Cond. magazine entry number0.20.31.3-0.5-0.4-1.0-0.5-0.2-0.4-0.2-0.1-0.1-1.1-0.50.1
Pavlov. Cond. intertrial magazine entries1.31.63.10.7-0.40.11.21.41.31.81.51.5-1.31.31.4
Pavlov. Cond. lever-magazine prob. diff.0.10.20.8-0.0-0.10.9-0.0-0.3-0.0-0.3-0.3-0.20.90.2-0.4
Pavlov. Cond. response bias0.40.51.90.60.31.40.70.30.60.40.40.41.20.70.3
Pavlov. Cond. lever latency0.60.81.70.4-0.8-0.21.20.90.91.31.01.0-1.10.60.6
Pavlov. Cond. magazine entry latency0.20.20.60.00.70.4-0.2-0.4-0.3-0.8-0.4-0.20.8-0.30.1
Pavlov. Cond. change in total contacts0.50.82.0-0.50.80.2-1.4-1.0-0.8-1.4-1.0-1.00.7-0.5-0.6
Pavlov. Cond. index score0.50.71.7-0.41.10.5-1.0-0.8-0.8-1.3-0.8-0.81.1-0.4-0.3
Pavlov. Cond. latency score0.50.71.9-0.50.80.2-1.1-1.0-0.8-1.4-1.0-0.80.7-0.6-0.4
Pavlov. Cond. lever contacts0.70.92.0-0.70.70.1-1.4-1.0-1.1-1.4-1.1-1.10.8-0.7-0.7
Pavlov. Cond. magazine entry number0.40.52.3-0.2-1.3-0.90.40.30.40.80.40.2-1.50.1-0.1
Pavlov. Cond. intertrial magazine entries0.10.21.5-0.2-1.2-0.40.00.0-0.10.4-0.0-0.2-0.5-0.1-0.2
Pavlov. Cond. lever-magazine prob. diff.0.50.71.5-0.31.20.6-0.9-0.7-0.7-1.2-0.8-0.71.2-0.3-0.3
Pavlov. Cond. response bias0.50.71.5-0.31.00.4-1.0-0.7-0.9-1.2-0.8-0.81.2-0.5-0.4
Time in closed arm before self-admin1.01.28.0-0.22.80.7-0.5-0.1-0.9-0.7-1.0-0.91.50.5-0.6
Time in closed arm after self-admin0.80.96.10.32.51.10.20.3-0.30.2-0.2-0.31.30.9-0.1
Time in open arm before self-admin0.20.31.70.2-1.30.00.30.20.40.50.60.5-0.2-0.00.3
Time in open arm after self-admin0.60.73.80.2-1.9-0.80.20.30.80.50.60.8-1.1-0.20.6
Bone: periosteal estimation2.14.47.02.62.02.21.92.22.31.82.02.02.02.01.9
Bone: periosteal perimeter3.86.510.33.13.22.12.42.72.82.32.52.41.82.42.5
Bone: post-yield work0.40.61.30.9-0.20.70.90.81.10.70.91.10.10.70.9
Progressive ratio test 1 active lever presses0.81.03.90.52.01.80.80.2-0.0-0.10.10.11.70.80.2
Progressive ratio test 1 breakpoint0.70.93.50.51.91.70.70.20.0-0.10.10.11.60.80.2
Progressive ratio test 1 inactive lever presses0.40.52.50.61.60.31.10.80.20.60.30.20.70.50.3
Progressive ratio test 2 active lever presses0.40.51.60.71.30.90.60.60.40.50.50.41.00.70.6
Progressive ratio test 2 breakpoint0.30.41.10.61.10.80.50.50.40.40.50.30.80.60.5
Progressive ratio test 2 inactive lever presses0.71.12.91.01.71.11.11.00.80.91.00.90.71.20.9
Incentive Sensitization - Responses0.10.10.20.40.40.5-0.10.20.30.30.30.20.40.30.3
Incentive Sensitization - Breakpoint0.00.10.10.30.10.3-0.10.20.30.20.30.20.30.20.2
Sum of active levers in priming session hrs 5-61.51.44.40.5-2.1-1.00.60.71.41.01.11.3-1.8-0.01.1
Progressive ratio0.10.20.40.3-0.2-0.40.10.40.60.40.50.6-0.60.10.5
Food seeking constrained by brief footshock2.42.95.41.5-0.5-0.21.21.82.32.22.12.2-1.41.32.0
Seeking ratio, punishment vs. effort0.40.61.50.5-0.60.30.80.80.91.20.90.9-0.30.80.8
Retroperitoneal fat weight2.08.513.83.23.43.72.62.92.52.42.12.33.73.22.2
Reaction time number correct0.10.30.70.6-0.80.30.70.50.60.50.30.10.70.2-0.0
Reaction time mean minus median0.20.61.4-0.80.0-0.1-0.9-1.0-1.0-1.2-1.1-0.60.3-0.7-0.5
Reaction time mean minus median AUC0.20.51.1-0.90.4-0.2-0.9-0.9-1.0-1.0-1.0-0.60.2-0.6-0.4
Reaction time num false alarms0.20.31.80.61.30.10.20.20.7-0.20.20.40.10.10.5
Reaction time num false alarms AUC0.10.21.30.51.2-0.10.00.10.7-0.30.20.3-0.2-0.00.5
Reaction time trials correct on left0.10.30.70.6-0.80.30.70.50.60.50.30.10.70.2-0.0
Reaction time trials on left0.10.30.70.6-0.70.30.70.50.60.50.30.10.80.20.0
Reaction time mean0.20.21.80.11.30.1-0.3-0.0-0.3-0.5-0.3-0.00.8-0.20.1
Reaction time mean AUC0.40.71.5-0.60.9-0.4-1.0-0.8-1.0-1.2-1.0-0.70.5-0.9-0.6
Median of all reaction times0.20.22.10.31.5-0.1-0.10.2-0.0-0.20.10.20.5-0.10.4
Reaction time omissions0.50.73.10.21.71.0-0.5-0.3-0.5-0.8-0.3-0.21.8-0.00.0
Reaction time false alarm rate0.30.42.20.51.50.30.10.20.7-0.00.60.7-0.20.40.8
Reaction time premature initiation rate0.10.10.5-0.1-0.70.50.2-0.30.1-0.10.10.2-0.20.0-0.2
Reaction time premature initiations0.10.10.60.1-0.80.60.4-0.20.3-0.00.1-0.00.40.1-0.3
Std. dev. reaction times0.10.20.90.00.80.4-0.3-0.2-0.5-0.6-0.3-0.01.0-0.30.1
Reaction time trials completed0.10.30.70.6-0.70.30.70.50.60.50.30.10.80.20.0
Reaction time trials AUC0.20.40.90.7-0.60.50.80.70.80.60.40.21.00.30.1
Run reversals in cocaine runway, females2.22.26.31.52.51.90.91.41.01.11.31.11.61.61.4
Run reversals in cocaine runway, males1.01.01.5-1.0-1.1-1.2-0.6-1.1-0.8-1.2-0.9-0.8-1.0-1.2-0.9
Latency to leave start box in cocaine runway0.10.10.70.10.10.7-0.00.1-0.10.20.2-0.20.80.30.1
Latency to leave start box in cocaine runway, F0.60.61.50.80.71.20.60.70.50.80.80.51.00.90.8
Latency to leave start box in cocaine runway, M0.80.81.2-1.0-0.6-0.6-1.0-0.9-1.0-0.9-1.0-1.0-0.2-0.8-1.1
Std. dev. time between licks in bursts1.72.34.61.71.62.11.11.51.31.41.11.31.71.90.9
Total sessions with >9 infusions2.02.57.01.62.61.72.01.51.01.11.21.11.61.51.2
Short access day 1 total inactive lever presses1.52.03.61.21.81.01.91.61.01.71.41.10.71.61.3
Short access day 10 total inactive lever presses1.84.46.9-2.3-0.2-2.0-2.3-2.2-2.5-2.2-2.2-2.4-1.2-1.9-2.6
Short access day 1 total infusions3.64.87.32.22.52.32.72.41.82.12.02.01.92.41.8
Short access day 10 total infusions1.11.42.31.01.31.41.21.21.01.41.01.00.91.51.2
Short access total infusions1.41.84.31.22.11.81.51.10.81.00.90.91.51.51.0
Short access day 1 locomotion3.34.19.32.03.12.02.02.31.52.01.71.61.82.31.6
Short access day 10 total locomotion1.83.34.91.91.41.52.12.21.62.22.01.71.11.82.0
Short access total locomotion2.83.44.12.02.01.92.02.01.61.91.91.61.21.91.9
One hour access (0.3 mA shock)1.31.52.41.10.91.11.01.31.31.51.31.30.31.51.6
Compulsive drug intake0.40.51.2-0.7-1.0-0.8-1.0-0.7-0.3-0.5-0.4-0.4-1.1-0.6-0.3
One hour access (shock baseline)1.32.03.81.42.01.41.31.51.21.31.31.21.21.51.3
Social response proportion5.96.79.52.81.61.92.72.93.02.93.03.10.32.72.7
Social responses2.63.35.51.80.11.31.82.02.22.32.22.20.11.92.0
Social time0.20.31.00.20.1-0.10.00.40.50.60.80.7-1.00.41.0
Soleus weight0.51.46.00.81.92.00.20.30.3-0.0-0.00.12.51.20.5
Bone: stiffness3.55.78.32.82.92.92.22.22.31.72.22.12.42.42.1
Tibialis anterior weight0.10.51.20.90.21.10.80.60.50.60.50.51.10.70.4
Time to tail flick, vehicle, before self-admin0.50.61.21.00.50.10.90.71.10.70.80.9-0.10.41.0
Time to tail flick, vehicle, after self-admin0.40.50.9-0.40.2-0.9-0.9-0.4-0.8-0.6-0.9-0.90.1-0.7-1.0
Time to tail flick, test, before self-admin0.70.72.30.91.50.60.70.90.80.60.90.90.20.90.7
Time to tail flick, test, after self-admin0.20.31.30.0-0.6-0.80.2-0.10.3-0.10.30.4-1.2-0.40.4
Delta time to tail flick, vehicle, before/after SA1.00.91.8-1.1-0.6-0.9-1.1-0.8-1.2-0.7-1.0-1.2-0.3-0.8-1.3
Delta time to tail flick, test, before/after SA0.20.21.60.1-1.3-0.10.2-0.00.30.30.20.2-0.3-0.20.4
Tibia length0.61.62.81.21.31.51.41.01.11.01.01.21.11.41.7
Ambulatory time before self-admin0.81.12.6-0.51.40.9-1.3-0.6-1.1-0.8-1.2-1.31.60.1-1.1
Ambulatory time after self-admin0.60.72.90.61.71.3-0.10.4-0.10.1-0.0-0.21.70.6-0.1
Bone: tissue strength0.50.51.3-0.20.3-0.0-1.0-0.6-0.7-0.9-0.7-0.70.8-0.7-1.2
Total heroin consumption0.30.41.1-0.10.50.4-0.5-0.6-0.4-1.1-0.7-0.50.8-0.5-0.7
Bone: trabecular number4.47.210.33.00.62.23.23.13.03.22.92.91.42.82.8
Bone: trabecular spacing0.91.32.2-1.20.0-0.8-1.5-1.3-1.3-1.4-1.2-1.4-0.2-1.2-0.9
Bone: trabecular thickness3.54.48.02.40.21.82.82.32.52.32.22.50.82.11.8
Bone: trabecular tissue density0.30.51.3-0.4-1.1-0.1-0.4-0.7-0.6-1.0-0.6-0.60.4-0.9-1.0
Water consumed over 24 hours0.60.82.21.0-0.31.51.00.71.00.70.91.00.80.90.4
Number of responses in last shaping day2.12.33.11.50.61.61.51.51.71.71.61.70.51.71.8