Arhgef28

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL mRNA stability Arhgef28 0.26 0.13 3.7e-08 0.08 0.06 0.07 0.07 6.6e-09 1.1e-06 1.8e-08 4.5e-08
2 BLA isoform ratio NM_001415065.1 0.08 0.05 1.4e-03 0.07 0.04 0.04 0.05 1.3e-04 2.7e-03 3.4e-03 1.7e-03
3 PL intron excision ratio chr2_31227347_31234535 0.06 0.03 7.6e-10 0.06 0.08 0.08 0.07 1.4e-07 9.4e-09 9.1e-09 2.9e-08
4 BLA mRNA stability Arhgef28 0.2 0.09 6.2e-09 0.16 0.13 0.13 0.13 5.9e-09 1.5e-07 1.4e-07 3.1e-07
5 IC mRNA stability Arhgef28 0.07 0.04 4.4e-04 0.04 0.06 0.02 0.03 9.9e-03 1.7e-03 5.7e-02 2.8e-02
6 BLA intron excision ratio chr2_31227347_31234535 0.09 0.05 8.7e-05 0.05 0.06 0.02 0.05 1.7e-03 5.3e-04 3.1e-02 1.4e-03
7 pVTA intron excision ratio chr2_31227347_31234535 0.04 0.02 1.2e-03 0.01 0.03 0 0.01 3.8e-02 2.2e-03 1.4e-01 6.2e-02
8 pVTA mRNA stability Arhgef28 0.04 0.03 5.4e-04 0.02 0.02 0.02 0.01 8.2e-03 1.1e-02 1.5e-02 2.4e-02
9 pVTA gene expression Arhgef28 0.12 0.06 4.0e-09 0.08 0.11 0.1 0.1 5.2e-07 3.4e-09 1.0e-08 8.9e-09
10 Brain intron excision ratio chr2_31176326_31234535 0.06 0.03 4.0e-06 0.04 0.02 0.03 0.01 4.6e-05 8.4e-03 1.9e-03 1.9e-02
11 PL intron excision ratio chr2_31176326_31234535 0.03 0.02 1.1e-03 0.03 0.01 0 0.02 4.0e-04 8.1e-03 1.4e-01 7.0e-03
12 Brain mRNA stability Arhgef28 0.09 0.04 2.6e-11 0.09 0.08 0.1 0.08 1.3e-08 7.3e-08 1.8e-09 1.0e-07
13 IC intron excision ratio chr2_31227347_31234535 0.09 0.07 2.2e-03 0.06 0.06 0.05 0.05 1.4e-03 1.8e-03 5.3e-03 4.8e-03
14 PL isoform ratio NM_001415065.1 0.1 0.05 2.3e-05 0.03 0.04 0.04 0.03 2.0e-04 3.9e-05 2.5e-05 4.4e-04
15 NAcc alternative TSS XM_063282028.1 0.05 0.04 3.4e-03 0.01 0.01 0.01 0.01 1.9e-02 3.1e-02 3.2e-02 2.5e-02
16 IC intron excision ratio chr2_31176326_31234535 0.16 0.14 6.0e-03 0.05 0.04 0.04 0.05 2.7e-03 1.0e-02 1.2e-02 3.1e-03
17 NAcc gene expression Arhgef28 0.09 0.04 0.0e+00 0.14 0.12 0.13 0.13 8.2e-20 4.7e-18 1.7e-19 2.9e-19
18 OFC gene expression Arhgef28 0.38 0.15 3.7e-03 0.17 0.13 0.12 0.13 7.6e-05 4.8e-04 7.4e-04 6.5e-04
19 PL gene expression Arhgef28 0.3 0.12 9.2e-05 0.04 0.03 0.02 0.03 8.7e-05 2.8e-04 2.3e-03 4.5e-04
20 IC gene expression Arhgef28 0.38 0.14 2.1e-04 0.08 0.05 0.03 0.04 3.0e-04 5.2e-03 1.6e-02 7.2e-03
21 PL isoform ratio XR_010063623.1 0.1 0.05 1.4e-05 0.02 0.05 0.04 0.03 1.4e-03 4.2e-06 1.0e-05 1.8e-04
22 BLA intron excision ratio chr2_31176326_31234535 0.18 0.09 5.1e-08 0.12 0.12 0.13 0.12 7.2e-07 8.6e-07 1.6e-07 4.6e-07
23 NAcc intron excision ratio chr2_31176326_31234535 0.04 0.03 1.7e-03 0.01 0.01 0.02 0.01 2.3e-02 3.8e-03 4.6e-04 7.3e-03
24 Adipose gene expression Arhgef28 0.12 0.06 1.8e-05 0.03 0.05 0.04 0.04 4.2e-04 7.6e-06 2.2e-05 3.1e-05
25 Adipose mRNA stability Arhgef28 0.05 0.03 7.2e-04 0 0.01 0.01 0 1.3e-01 2.6e-02 1.5e-02 9.5e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25
Bone: apparent density0.20.31.20.60.5-0.80.40.4-0.6-0.30.4-0.10.40.40.6-0.21.1-0.20.70.2-0.7-1.0-0.8-1.00.30.20.70.6
Area under the delay curve0.60.71.8-1.1-0.91.1-1.1-0.90.80.7-0.9-0.8-1.0-1.0-0.61.0-0.61.0-1.0-1.3-0.7-0.2-0.50.4-0.4-0.6-0.4-0.0
BMI with tail1.13.68.1-2.5-2.82.2-2.2-2.32.22.2-1.8-1.9-1.5-1.5-2.62.0-2.32.0-1.7-2.4-1.0-0.5-0.91.5-0.70.0-1.6-2.2
BMI without tail1.23.57.0-2.4-2.61.9-1.9-2.12.32.3-2.0-2.0-1.7-1.7-2.31.9-2.62.0-1.8-1.9-1.1-0.5-0.82.3-1.1-0.8-0.4-1.6
Body weight1.87.817.9-3.9-4.03.5-3.3-3.03.33.0-2.7-2.4-2.5-2.5-3.23.0-4.22.8-2.7-2.8-0.60.1-0.33.8-1.5-1.2-1.6-2.2
Weight adjusted by age0.10.21.90.30.20.10.2-0.20.30.2-0.2-0.0-0.5-0.5-0.20.4-0.40.5-0.60.2-0.2-0.1-0.00.2-1.0-1.40.4-0.2
Bone surface0.10.20.4-0.4-0.40.5-0.4-0.50.30.4-0.6-0.4-0.6-0.6-0.30.60.00.6-0.1-0.6-0.4-0.5-0.3-0.3-0.20.1-0.3-0.1
Bone volume0.30.51.01.00.9-0.90.90.7-0.8-0.80.60.70.60.60.8-0.51.0-0.51.00.50.50.20.4-1.00.70.5-0.10.4
Breakpoint value in progressive ratio session0.30.31.60.70.3-0.30.00.2-0.4-0.10.2-0.50.50.50.3-0.20.4-0.2-0.40.0-1.3-1.2-1.0-0.50.0-0.00.90.7
Number of licking bursts0.30.53.3-0.20.1-0.90.40.5-0.4-0.10.6-0.40.60.60.4-0.90.1-0.80.41.1-0.5-0.8-0.80.60.50.11.81.0
Context. condit. distance diff. score1.41.73.11.01.1-1.41.21.6-1.4-1.51.61.41.61.61.4-1.80.4-1.61.01.51.41.71.70.01.30.60.21.0
Locomotion velocity, session 10.50.51.40.70.8-1.10.40.9-0.6-0.71.20.61.21.20.6-0.8-0.0-0.90.50.70.50.10.20.60.80.10.0-0.2
Locomotion distance, session 10.81.12.20.81.2-1.40.91.3-1.3-1.21.50.81.51.51.0-1.10.8-1.11.01.00.60.40.4-0.41.41.0-0.30.1
Locomotion velocity, session 20.40.41.60.10.3-0.70.10.9-0.6-0.70.30.70.30.31.1-0.80.1-0.80.50.60.70.50.50.40.4-0.31.11.3
Locomotion distance, session 21.62.23.91.82.0-2.01.51.9-1.8-1.71.81.31.81.81.6-1.61.3-1.61.81.61.20.60.7-0.51.70.90.00.3
Locomotion velocity, session 30.40.52.20.30.3-0.40.20.4-0.1-0.40.70.80.70.70.1-0.6-0.5-0.50.20.51.51.51.31.00.5-0.1-0.3-0.2
Locomotion distance, session 30.40.53.20.10.40.00.40.00.2-0.10.20.90.20.2-0.2-0.2-0.3-0.00.30.61.61.81.60.4-0.0-0.6-0.7-0.7
Stereotopy head waving bouts, day 30.60.71.90.60.5-0.90.61.1-1.0-1.11.20.71.21.20.9-0.90.2-0.90.60.80.80.70.50.31.41.0-0.50.2
Stereotopy head waving duration, day 30.20.21.3-0.6-0.80.2-0.60.1-0.2-0.20.1-0.40.10.10.20.1-0.50.0-0.4-0.4-0.4-0.4-0.40.70.71.1-0.80.0
Locomotion velocity, session 71.41.65.30.70.7-1.00.61.2-0.9-1.21.31.61.31.31.1-1.4-0.1-1.31.21.42.22.02.30.41.20.50.10.8
Locomotion distance, session 70.20.31.10.10.2-0.40.20.5-0.4-0.40.50.40.50.50.7-0.7-0.0-0.60.40.70.70.40.60.20.2-0.31.01.1
Stereotopy head waving bouts, day 70.91.02.30.40.3-1.10.41.2-1.2-1.11.20.71.21.21.3-1.50.3-1.40.71.30.70.70.60.21.31.20.61.5
Stereotopy head waving duration, day 70.10.10.4-0.1-0.2-0.2-0.20.2-0.1-0.20.20.20.20.20.3-0.5-0.4-0.3-0.10.30.30.60.50.70.40.60.20.6
Locomotion velocity, session 83.84.57.82.42.4-2.32.22.5-2.1-2.32.12.62.12.12.4-2.51.5-2.42.02.82.62.42.4-0.81.70.50.71.5
Locomotion distance, session 81.21.83.01.41.6-1.71.31.7-1.4-1.51.61.41.61.61.6-1.70.7-1.51.01.51.41.31.40.01.0-0.10.61.0
Degree of sensitization distance0.50.61.70.50.4-0.90.50.9-0.9-0.80.80.30.80.81.1-1.00.4-1.00.60.8-0.2-0.5-0.2-0.10.90.71.01.3
Degree of sensitization stereotypy0.60.71.90.30.2-0.90.20.9-0.9-0.80.90.60.90.91.0-1.30.4-1.10.60.90.40.50.4-0.11.11.20.61.4
Conditioned locomotion0.30.32.4-0.10.00.30.1-0.3-0.10.1-0.3-0.2-0.3-0.3-0.40.11.20.10.1-0.3-0.6-0.8-0.8-1.6-0.00.8-0.9-0.6
Cocaine response after cond. corrected0.20.20.5-0.3-0.30.5-0.4-0.50.70.5-0.5-0.2-0.5-0.5-0.60.5-0.70.5-0.3-0.60.10.20.20.7-0.4-0.6-0.2-0.7
Cocaine response after cond. not corrected0.30.32.6-0.3-0.30.3-0.4-0.20.50.3-0.10.1-0.1-0.1-0.50.2-1.20.2-0.2-0.20.70.80.81.6-0.1-0.6-0.4-0.7
Cocaine response before conditioning0.70.82.20.30.3-0.80.40.8-0.6-0.81.11.01.11.10.5-1.0-0.4-1.00.71.11.41.51.41.01.00.5-0.40.2
Saline control response0.10.11.3-0.2-0.10.20.1-0.30.00.1-0.0-0.0-0.0-0.0-0.30.10.60.20.30.1-0.0-0.3-0.1-1.20.20.4-0.6-0.1
Bone: connectivity density0.50.73.6-0.6-0.80.5-0.9-0.70.30.7-0.7-1.2-0.7-0.7-0.30.80.20.7-0.3-0.8-1.6-1.9-1.6-0.5-0.30.10.60.4
Bone: cortical apparent density1.31.73.11.71.8-1.51.71.4-1.3-1.41.61.41.61.61.1-1.21.1-1.31.41.31.21.01.2-0.71.40.9-0.30.1
Bone: cortical area1.32.05.81.91.5-0.31.70.7-0.9-1.40.52.20.50.50.7-0.51.4-0.51.20.82.12.22.3-2.20.61.4-2.4-0.5
Bone: cortical porosity1.71.88.10.50.4-0.70.70.9-1.0-1.11.50.81.51.50.2-0.8-0.2-0.91.30.41.51.51.30.42.52.6-2.8-1.6
Bone: cortical porosity3.13.310.51.11.0-1.31.41.6-1.8-1.92.21.52.22.21.0-1.60.5-1.62.01.12.02.01.8-0.33.03.2-2.7-0.9
Bone: cortical thickness2.13.46.62.62.2-1.22.41.3-1.5-1.91.52.61.51.51.1-1.11.9-1.21.91.32.22.42.4-2.51.21.8-2.3-0.5
Bone: cortical thickness1.11.37.30.10.40.20.80.2-0.2-0.70.21.60.20.20.1-0.4-0.3-0.40.60.32.32.72.70.01.11.4-2.1-0.2
Bone: cortical tissue density1.21.62.81.61.7-1.51.61.4-1.2-1.31.61.41.61.61.1-1.21.0-1.31.41.31.21.01.2-0.61.40.9-0.20.2
Condit. Reinf. active minus inactive responses0.50.63.1-0.10.0-0.70.10.6-0.7-0.40.5-0.40.50.50.9-0.50.6-0.60.20.4-0.9-1.3-1.3-0.30.30.21.61.8
Condit. Reinf. active-inactive response ratio0.20.20.8-0.0-0.1-0.4-0.10.2-0.3-0.10.3-0.30.30.30.3-0.30.2-0.30.00.3-0.8-0.8-0.8-0.20.00.50.90.9
Condit. Reinf. active responses0.50.63.6-0.20.0-0.70.10.5-0.6-0.30.4-0.40.40.40.9-0.40.5-0.50.10.3-0.8-1.3-1.3-0.10.1-0.41.91.8
Condit. Reinf. inactive responses0.20.22.1-0.20.10.1-0.20.00.00.1-0.3-0.3-0.3-0.30.40.20.20.1-0.3-0.3-0.2-0.6-0.60.1-0.5-1.51.00.8
Incentive salience index mean0.60.73.5-0.8-0.6-0.4-0.60.2-0.3-0.00.1-1.00.10.10.7-0.10.0-0.1-0.30.0-1.3-1.7-1.70.4-0.2-0.71.91.7
Condit. Reinf. lever presses0.40.62.9-0.9-0.6-0.1-0.7-0.10.10.3-0.3-1.0-0.3-0.30.20.4-0.50.4-0.6-0.1-1.0-1.2-1.21.1-0.6-1.71.40.8
Condit. Reinf. active minus inactive responses0.81.02.81.71.6-1.21.10.9-0.8-0.90.91.21.01.00.9-1.01.1-1.00.91.40.60.40.5-1.20.1-0.30.90.9
Condit. Reinf. active-inactive response ratio0.30.31.01.01.0-0.50.80.4-0.3-0.30.70.70.70.70.1-0.40.2-0.40.60.70.60.40.5-0.40.20.1-0.1-0.4
Condit. Reinf. active responses0.60.93.11.81.5-1.21.10.9-0.7-0.80.81.20.90.90.7-0.90.9-0.90.71.30.60.60.7-0.8-0.0-0.60.90.6
Condit. Reinf. inactive responses0.20.31.3-0.2-0.50.2-0.6-0.40.40.4-0.6-0.4-0.5-0.5-0.30.4-0.20.4-0.7-0.3-0.6-0.4-0.40.3-0.9-1.10.50.3
Condit. Reinf. lever presses0.50.72.61.61.4-1.21.00.8-0.7-0.70.80.80.90.90.6-0.70.6-0.70.91.20.60.50.7-0.60.4-0.30.50.4
Condit. Reinf. lever reinforcers received0.50.62.91.71.5-1.01.10.6-0.5-0.60.61.00.70.70.4-0.70.7-0.70.61.10.50.50.6-0.8-0.2-0.70.60.2
Conditioned reinforcement - actives1.32.24.6-0.9-1.02.1-0.9-2.12.02.0-2.1-1.2-1.8-1.8-1.91.9-0.41.8-1.3-1.2-0.5-0.8-0.8-0.7-2.0-0.9-0.2-1.5
Conditioned reinforcement - inactives0.20.31.20.40.20.60.2-0.40.40.3-0.70.4-0.2-0.2-0.30.10.20.10.40.31.11.01.0-0.7-0.00.3-0.6-0.7
Conditioned locomotion0.60.72.00.30.31.30.4-1.01.00.7-1.00.7-0.6-0.6-1.10.60.30.5-0.2-0.31.21.31.2-1.4-0.60.2-1.1-1.4
Patch foraging indifference point 0 sec1.12.05.4-1.8-1.51.5-1.6-1.41.81.5-1.4-0.8-1.4-1.4-1.21.3-2.01.2-1.6-0.60.30.40.52.1-1.5-2.30.80.1
Patch foraging indifference point AUC0.40.61.5-0.7-0.80.8-0.8-0.90.70.9-0.6-1.1-0.6-0.6-0.90.9-0.30.8-0.7-1.1-1.2-1.0-1.2-0.1-0.8-0.5-0.0-0.6
Delay disc. indifference point, 0s delay1.71.94.90.71.0-1.91.01.7-1.6-1.62.01.11.71.71.9-1.60.5-1.61.01.70.20.60.3-0.11.70.51.32.2
Delay disc. indifference point, 16s delay0.80.82.3-0.5-0.71.5-0.8-1.11.00.9-1.3-0.4-1.3-1.3-0.91.2-0.21.2-0.6-1.3-0.20.1-0.0-0.4-0.9-0.6-0.9-0.8
Delay disc. indifference point, 2s delay0.10.11.3-0.4-0.10.1-0.00.0-0.1-0.2-0.1-0.1-0.1-0.10.50.3-0.10.3-0.5-0.1-0.3-0.1-0.30.0-0.1-1.00.61.1
Delay disc. indifference point, 24s delay3.03.35.3-2.3-2.01.6-1.9-1.91.71.9-1.7-2.2-2.1-2.1-1.62.1-0.92.0-1.9-2.1-1.9-1.7-2.01.1-1.9-2.30.2-0.7
Delay disc. indifference point, 4s delay0.50.52.6-0.4-0.1-0.8-0.10.8-0.8-0.70.90.10.80.81.0-0.6-0.4-0.60.40.5-0.20.1-0.20.61.61.20.31.4
Delay disc. indifference point, 8s delay0.91.12.6-1.6-1.31.4-1.5-1.11.01.0-0.9-1.1-1.0-1.0-1.01.1-0.91.1-1.2-1.6-0.6-0.3-0.50.8-0.5-0.7-0.6-0.3
Indifference point function ln k0.20.31.20.30.30.00.40.2-0.1-0.30.10.70.10.10.0-0.4-0.2-0.30.50.51.00.91.10.00.71.1-0.9-0.4
Indifference point function log k0.20.31.20.30.30.00.40.2-0.1-0.30.10.70.10.10.0-0.4-0.2-0.30.50.51.00.91.10.00.71.1-0.9-0.4
Patch foraging total patch changes 0 sec1.12.15.5-1.8-1.61.6-1.7-1.41.81.5-1.5-0.8-1.5-1.5-1.21.2-2.11.3-1.6-0.60.30.40.52.1-1.5-2.30.70.2
Patch foraging total patch changes 12 sec0.71.02.7-1.6-1.31.0-1.2-1.11.21.1-0.6-1.0-0.7-0.7-1.21.2-1.31.1-1.0-1.1-0.5-0.3-0.41.2-0.4-0.7-0.3-0.6
Patch foraging total patch changes 18 sec0.30.41.4-0.9-0.80.7-0.7-0.60.80.6-0.6-0.1-0.7-0.7-0.50.5-1.00.5-0.5-0.30.40.70.60.9-0.7-1.20.30.4
Patch foraging total patch changes 24 sec1.01.84.3-1.5-1.61.8-1.4-1.41.71.3-1.0-0.3-1.1-1.1-1.71.2-2.11.1-1.2-1.30.81.31.11.7-0.7-0.7-1.4-1.3
Patch foraging total patch changes 6 sec1.52.34.9-2.1-2.11.3-2.2-1.51.71.7-1.3-1.6-1.3-1.3-1.31.4-2.01.3-1.9-1.1-0.8-0.7-0.52.2-1.2-1.91.00.2
Patch foraging time to switch 0 sec0.10.10.40.10.2-0.40.10.5-0.5-0.60.40.30.40.40.6-0.30.1-0.4-0.00.00.30.10.20.40.2-0.50.10.5
Patch foraging water rate 0 sec0.20.31.6-0.8-0.70.6-0.6-0.50.70.6-0.3-0.1-0.2-0.2-0.70.1-1.30.2-0.4-0.10.40.70.71.10.00.5-0.2-0.4
Patch foraging water rate 12 sec1.63.410.21.41.2-1.01.61.0-0.8-1.22.02.41.81.80.1-1.5-0.1-1.52.01.43.03.23.1-0.12.12.6-2.4-1.4
Patch foraging water rate 18 sec0.50.73.3-0.1-0.40.4-0.4-0.60.90.60.10.30.00.0-1.30.3-1.20.3-0.2-0.51.01.51.40.90.40.8-1.5-1.8
Patch foraging water rate 24 sec0.50.73.2-0.7-0.80.8-0.5-0.60.60.30.10.40.00.0-1.0-0.1-0.90.0-0.3-0.41.21.31.30.40.61.2-1.8-1.2
Patch foraging water rate 6 sec1.82.68.71.21.2-0.81.21.2-1.0-1.51.42.31.11.10.8-1.40.3-1.31.91.42.72.92.7-0.41.81.8-2.3-0.6
Seeking ratio, delayed vs. immediate footshock0.81.06.3-0.5-0.3-0.3-0.2-0.2-0.30.3-0.0-1.3-0.2-0.20.10.11.60.2-0.1-0.3-1.8-2.5-2.3-1.6-0.0-0.11.20.8
Distance traveled before self-admin0.30.42.9-0.7-1.20.1-1.2-0.00.10.20.4-0.6-0.1-0.1-0.2-0.1-1.4-0.3-0.7-0.4-0.50.2-0.21.70.80.20.00.2
Distance traveled after self-admin1.51.94.0-1.4-1.50.9-1.8-1.31.51.6-1.3-1.7-1.5-1.5-1.31.2-1.61.0-1.8-0.9-1.3-0.8-0.92.0-1.1-1.71.1-0.1
Extensor digitorum longus weight0.10.61.5-0.3-0.50.7-0.4-0.50.70.4-0.60.0-0.6-0.6-0.70.7-1.10.6-0.8-0.40.81.11.11.2-0.4-0.8-1.2-1.2
Bone: elastic displacement1.72.06.31.81.6-0.91.91.0-0.9-1.11.11.31.11.10.3-0.60.3-0.61.90.91.61.71.7-0.11.81.9-2.5-2.0
Bone: elastic work1.21.69.91.41.2-0.51.70.6-0.6-0.80.81.00.80.8-0.1-0.00.3-0.11.50.51.41.41.5-0.21.51.7-3.1-2.3
Bone: endosteal estimation0.20.41.3-0.6-0.60.8-0.5-0.30.50.2-0.70.3-0.7-0.7-0.20.2-1.00.3-0.5-0.20.91.01.10.9-0.2-0.1-0.4-0.0
Bone: endosteal perimeter0.00.10.80.1-0.10.1-0.20.0-0.0-0.1-0.30.3-0.3-0.30.2-0.10.20.00.10.20.40.30.5-0.4-0.20.9-0.00.5
Epididymis fat weight1.44.912.1-2.7-2.42.8-2.5-2.52.82.5-2.1-1.7-1.9-1.9-2.92.4-3.52.2-1.8-2.1-0.10.30.23.1-1.1-0.8-1.8-2.6
Delta time in closed arm before/after self-admin0.60.63.40.81.1-0.30.90.4-0.8-0.50.30.10.20.20.7-0.31.4-0.31.10.5-0.6-1.1-0.9-1.80.20.40.20.3
Delta time in open arm before/after self-admin0.30.21.50.0-0.40.2-0.4-0.40.70.5-0.3-0.1-0.4-0.4-0.60.5-0.80.5-0.6-0.30.30.40.41.2-0.5-0.4-0.1-0.5
Diff in mean of infusions in LGA sessions0.20.20.90.90.8-0.40.30.6-0.8-0.70.60.20.50.50.6-0.30.5-0.20.30.1-0.3-0.1-0.3-0.80.30.7-0.30.2
Delay discount exponential model param0.80.92.21.31.0-1.31.21.1-0.9-0.91.11.01.11.10.8-1.20.7-1.21.11.50.90.40.7-0.50.60.80.30.1
Extinction: sum of active levers before priming0.40.42.40.1-0.1-0.2-0.30.0-0.10.3-0.0-0.90.10.10.10.1-0.30.1-0.30.1-1.5-1.3-1.40.3-0.1-0.11.40.7
Active lever presses in extinction session 61.51.53.1-0.9-0.91.5-0.8-1.51.21.4-1.7-1.5-1.5-1.5-1.21.8-0.01.7-1.3-1.5-1.4-1.2-0.9-0.6-1.2-0.8-0.3-0.6
Bone: final force1.21.95.91.21.1-0.91.51.1-1.1-1.51.31.81.31.30.9-0.80.6-0.81.31.02.01.92.1-0.61.41.6-2.4-0.8
Bone: final moment1.11.88.21.00.9-0.61.30.9-0.9-1.41.11.81.11.10.6-0.60.3-0.61.10.72.12.12.2-0.31.31.6-2.9-1.2
Food consumed during 24 hour testing period0.00.00.3-0.3-0.30.0-0.2-0.20.30.3-0.00.00.00.0-0.30.0-0.30.00.00.30.10.20.10.2-0.00.10.50.3
Glucose2.53.97.32.62.7-2.22.52.2-2.2-2.41.82.31.81.82.3-1.82.2-1.82.31.61.61.31.5-1.91.71.6-0.21.1
Heart weight1.42.13.4-1.8-1.51.6-1.4-1.51.41.4-1.3-1.8-1.3-1.3-1.71.7-1.41.7-1.5-1.5-1.5-1.5-1.41.3-1.0-0.3-1.1-1.9
Delay discount hyperbolic model param0.60.71.61.20.9-1.01.00.9-0.7-0.70.91.00.90.90.5-1.00.5-1.01.01.30.90.50.7-0.30.40.70.1-0.2
Intermittent access intake day 1-15 change0.20.41.00.90.9-0.40.80.2-0.1-0.30.41.00.50.50.1-0.50.4-0.50.60.81.00.91.0-0.60.50.9-0.2-0.2
Intermittent access intake escalation0.10.31.00.91.0-0.50.90.2-0.2-0.30.30.80.40.40.2-0.30.8-0.30.50.70.60.40.5-0.90.30.6-0.1-0.1
Intermittent access intake escalation 20.20.20.80.70.7-0.10.60.1-0.0-0.10.10.80.30.3-0.0-0.30.6-0.40.60.60.70.60.6-0.90.20.7-0.2-0.4
Intermitt. access day 1 inactive lever presses0.51.95.01.91.6-0.81.41.1-1.0-1.20.82.01.01.00.9-1.31.1-1.21.91.62.22.22.1-1.20.90.8-0.7-0.1
Intermitt. access day 15 inactive lever presses0.51.01.91.11.4-1.21.31.2-0.9-1.00.71.10.90.91.2-1.00.7-1.11.11.31.21.01.20.01.00.40.40.7
Intermitt. access escalation Index0.50.71.70.80.7-1.10.70.9-0.5-0.71.00.90.80.80.6-0.7-1.0-0.60.40.30.91.21.11.31.10.8-0.00.4
Intermittent access day 1 total infusions3.15.08.8-2.4-2.63.0-2.5-2.62.82.7-2.8-2.1-2.6-2.6-2.62.3-2.82.3-2.3-2.3-1.1-0.8-0.92.1-1.8-0.7-0.4-1.8
Intermittent access day 15 total infusions0.60.91.7-0.6-0.71.2-0.6-1.21.31.2-1.3-0.6-1.3-1.3-1.21.2-0.71.1-1.0-0.9-0.3-0.3-0.30.2-0.80.1-0.6-1.1
Intermittent access terminal intake (last 3 days)0.50.71.6-0.5-0.61.2-0.5-1.11.11.1-1.3-0.5-1.1-1.1-1.10.9-0.40.8-0.7-0.6-0.3-0.4-0.4-0.1-0.70.4-0.4-0.9
Intermittent access total infusions1.11.32.9-1.1-1.21.7-1.0-1.51.51.4-1.6-0.9-1.5-1.5-1.51.3-0.91.2-1.1-1.1-0.4-0.4-0.40.4-0.90.1-0.7-1.2
Intermittent access day 1 locomotion1.31.64.3-1.1-1.22.1-1.1-1.51.41.3-1.9-0.9-1.7-1.7-1.41.6-1.01.5-1.2-1.5-0.4-0.3-0.30.2-0.9-0.1-1.3-1.3
Intermittent access day 15 total locomotion1.63.07.9-1.2-1.52.8-1.6-2.22.21.9-2.4-0.9-2.2-2.2-2.21.9-1.42.0-1.7-1.7-0.2-0.00.10.7-1.6-0.3-1.6-2.2
Intermittent access total locomotion1.21.44.6-0.7-0.72.1-0.7-1.51.51.2-1.8-0.4-1.7-1.7-1.51.4-0.61.4-0.9-1.20.30.20.3-0.1-0.80.1-1.5-1.7
Intermittent access standard deviation0.10.10.5-0.2-0.20.6-0.2-0.40.40.5-0.7-0.4-0.5-0.5-0.30.3-0.10.3-0.1-0.0-0.4-0.3-0.50.0-0.3-0.10.2-0.1
Left kidney weight4.420.434.8-5.9-5.85.4-5.4-5.35.25.2-4.7-4.8-4.6-4.6-5.34.9-4.94.9-4.7-5.1-3.0-2.4-2.54.1-3.4-2.0-1.4-3.4
Right kidney weight4.018.331.4-5.5-5.65.3-5.1-5.04.94.8-4.4-4.4-4.6-4.6-4.94.8-4.64.8-4.4-4.7-2.5-2.2-2.13.7-3.2-2.2-1.7-3.0
Cocaine induced anxiety0.60.93.0-0.5-0.40.6-0.5-0.60.10.3-0.8-1.3-1.2-1.2-0.31.20.71.1-1.0-1.0-1.6-1.7-1.7-0.9-0.9-0.6-0.40.0
Post-drug Anxiety1.51.63.0-1.3-1.01.3-1.2-1.10.70.8-1.3-1.6-1.6-1.6-0.81.7-0.21.6-1.7-1.7-1.7-1.6-1.6-0.1-1.3-0.7-0.9-0.5
Baseline Anxiety0.10.20.8-0.5-0.30.2-0.3-0.00.20.00.20.30.10.1-0.2-0.1-0.7-0.0-0.1-0.10.70.80.70.90.1-0.2-0.5-0.4
Tail length0.52.110.1-2.2-2.11.7-1.7-1.11.51.3-1.4-1.0-1.2-1.2-0.91.0-2.91.0-1.4-0.80.30.70.83.2-0.6-0.80.30.2
Length with tail1.25.313.6-3.3-3.03.0-2.7-2.32.72.2-2.3-1.6-2.3-2.3-2.02.3-3.62.2-2.5-1.90.20.60.73.7-1.9-2.1-0.6-0.9
Length without tail0.62.05.7-2.4-2.22.0-1.9-1.41.51.2-1.2-0.9-1.3-1.3-1.21.5-2.01.3-1.5-1.20.50.20.41.9-1.0-1.3-1.0-0.6
Times rat made contact with spout1.21.34.9-1.2-0.90.6-0.7-1.31.01.4-0.8-1.6-0.8-0.8-1.61.2-0.21.2-0.6-0.8-1.8-2.2-2.2-0.2-0.8-0.40.1-1.1
Lifetime Intake1.41.63.5-1.3-1.41.9-1.2-1.61.61.6-1.8-1.1-1.7-1.7-1.61.4-1.11.3-1.3-1.2-0.5-0.6-0.60.6-1.0-0.1-0.5-1.1
Liver weight, left1.21.94.7-2.2-2.11.5-2.0-1.51.51.4-1.0-1.3-1.1-1.1-1.51.4-2.01.4-1.2-1.8-0.4-0.6-0.31.7-0.5-0.6-0.8-1.0
Liver weight, right1.22.06.7-2.3-2.61.9-2.1-1.71.61.5-1.4-1.2-1.2-1.2-1.71.3-1.71.3-1.3-1.6-0.2-0.2-0.11.4-0.4-0.3-1.0-1.0
Locomotor activity0.10.20.8-0.1-0.3-0.1-0.2-0.10.30.10.40.30.40.4-0.4-0.1-0.60.00.00.60.80.90.80.80.30.1-0.6-0.5
Locomotor testing distance0.71.33.1-0.8-1.11.4-1.1-1.51.71.4-1.3-0.4-1.1-1.1-1.71.1-1.31.3-1.0-0.50.40.60.50.8-1.4-1.5-0.3-1.1
Locomotor testing rearing0.20.41.6-0.6-0.70.9-0.5-1.10.90.8-0.6-0.2-0.3-0.3-1.20.50.00.6-0.1-0.10.20.30.1-0.9-0.40.1-0.6-0.8
Locomotion in novel chamber0.40.52.00.91.0-0.51.10.5-0.6-0.50.30.50.60.60.5-0.60.9-0.51.00.50.0-0.6-0.3-1.40.40.40.60.6
Locomotion in novel chamber post-restriction0.10.10.6-0.40.0-0.40.10.4-0.5-0.20.3-0.60.20.20.4-0.20.1-0.10.20.3-0.3-0.3-0.80.20.70.30.40.2
Fecal boli incidents, locomotor time 10.30.41.0-1.0-0.80.5-0.8-0.70.60.7-0.6-0.8-0.8-0.8-0.70.6-0.30.6-0.8-0.3-0.7-0.6-0.70.1-0.5-0.7-0.2-0.5
Change in fecal boli incidents, locomotor task0.20.21.00.30.6-0.30.60.2-0.2-0.10.30.10.30.30.2-0.40.7-0.31.0-0.10.10.0-0.1-0.60.40.90.60.1
Time >=10cm from walls, locomotor time 10.30.31.90.70.50.70.3-0.30.40.3-0.30.3-0.4-0.4-0.70.3-0.20.30.30.30.50.90.90.10.01.0-0.9-1.4
Bouts of movement, locomotor time 10.10.20.70.0-0.5-0.3-0.2-0.10.10.10.4-0.30.00.0-0.10.1-0.50.0-0.50.1-0.9-0.7-0.80.6-0.5-0.10.40.2
Total resting periods, locomotor time 10.20.20.9-0.2-0.6-0.1-0.4-0.20.20.20.2-0.5-0.2-0.2-0.20.4-0.40.2-0.5-0.1-0.9-0.8-1.00.5-0.6-0.20.30.1
Rest time, locomotor task time 10.81.02.50.60.7-1.20.91.1-0.9-0.91.60.91.41.40.8-1.10.1-1.21.11.41.10.70.70.41.31.1-0.10.1
Distance moved, locomotor task time 10.91.43.4-0.7-0.91.4-0.9-1.21.11.2-1.9-1.0-1.7-1.7-0.81.30.21.3-1.1-1.4-1.0-0.8-0.5-0.4-1.6-1.60.60.0
Vertical activity count, locomotor time 10.41.02.0-0.4-0.61.0-0.8-1.00.70.8-1.3-0.8-1.3-1.3-0.61.10.71.1-0.9-1.3-1.1-0.7-0.6-1.4-1.4-1.40.40.3
Time >=10cm from walls, locomotor time 20.10.20.6-0.5-0.20.6-0.3-0.40.60.5-0.1-0.2-0.3-0.3-0.60.6-0.30.60.1-0.10.2-0.10.20.7-0.1-0.1-0.5-0.8
Bouts of movement, locomotor time 20.20.31.0-0.3-0.60.2-0.4-0.30.50.4-0.1-0.4-0.4-0.4-0.20.5-1.00.4-0.6-0.3-0.5-0.3-0.41.0-0.8-0.70.40.2
Total resting periods, locomotor time 20.10.21.0-0.0-0.4-0.3-0.20.10.10.10.4-0.30.00.00.20.0-0.8-0.0-0.40.2-0.5-0.4-0.41.0-0.5-0.31.00.7
Rest time, locomotor task time 21.51.93.71.51.0-1.61.01.5-1.5-1.41.61.21.71.71.6-1.80.6-1.91.31.60.70.70.4-0.41.51.91.11.5
Distance moved, locomotor task time 20.81.02.4-0.9-0.81.3-0.6-1.11.00.9-1.3-0.8-1.3-1.3-1.01.40.21.5-0.6-1.4-0.5-0.7-0.3-0.2-0.9-1.0-1.0-1.1
Vertical activity count, locomotor time 20.20.31.0-0.3-0.10.6-0.1-0.70.50.5-0.5-0.2-0.5-0.5-0.70.80.60.80.1-0.8-0.1-0.2-0.0-1.0-0.2-0.3-1.0-0.9
Light reinforcement 10.30.81.8-1.1-1.21.1-1.1-1.31.11.1-0.8-0.9-0.8-0.8-1.31.2-0.71.2-0.9-0.9-0.5-0.3-0.40.0-0.9-0.3-0.4-0.5
Light reinforcement 20.81.22.7-1.3-1.31.0-1.1-1.10.80.9-0.4-1.2-0.5-0.5-1.31.3-0.81.1-1.2-1.4-1.2-1.2-1.30.5-0.50.4-1.6-1.7
Bone: marrow area0.20.31.2-0.6-0.60.8-0.4-0.30.50.2-0.60.4-0.6-0.6-0.10.2-1.00.3-0.4-0.20.91.01.10.9-0.2-0.0-0.40.1
Bone: maximum diameter0.30.51.4-0.0-0.51.2-0.2-0.70.60.2-1.00.4-1.0-1.0-0.40.7-0.20.7-0.5-0.30.70.70.9-0.4-0.70.4-1.2-0.2
Bone: maximum force0.61.04.30.90.9-0.31.10.4-0.3-0.80.61.50.60.60.1-0.10.1-0.20.70.61.71.81.9-0.50.50.7-2.1-1.1
Bone: maximum moment0.61.05.90.70.70.00.90.2-0.1-0.60.41.40.40.4-0.10.1-0.20.00.50.41.81.92.0-0.20.40.7-2.4-1.4
Mean time between licks in bursts0.00.10.5-0.2-0.50.4-0.6-0.20.20.1-0.3-0.3-0.2-0.2-0.10.2-0.40.3-0.7-0.0-0.3-0.2-0.30.7-0.50.1-0.20.1
Mean num. licks in bursts0.60.92.1-0.3-0.51.0-0.7-1.10.80.7-0.9-0.5-0.9-0.9-1.21.40.11.4-0.8-1.2-0.6-0.6-0.6-1.0-1.1-0.5-1.4-1.4
Cd content in liver0.70.81.51.11.0-0.61.00.6-0.7-0.80.81.00.80.80.4-0.71.2-0.70.90.61.01.21.2-1.20.81.2-0.8-0.0
Co content in liver0.20.31.00.10.10.2-0.3-0.40.70.5-0.10.2-0.1-0.1-0.80.2-0.80.2-0.4-0.20.61.00.90.7-0.4-0.7-0.2-0.9
Cu content in liver0.20.21.00.0-0.2-0.2-0.2-0.10.10.2-0.1-0.5-0.1-0.1-0.10.2-0.10.3-0.5-0.2-0.9-1.0-0.90.1-0.6-1.00.70.1
Fe content in liver3.03.77.31.41.5-2.01.92.1-2.3-2.22.21.82.22.22.0-2.21.7-2.12.11.91.61.51.5-1.62.62.7-0.61.1
K content in liver0.40.41.1-0.9-0.40.6-0.7-0.70.40.4-0.5-0.6-0.5-0.5-0.40.70.50.7-0.5-0.9-0.7-1.0-1.0-0.9-0.8-0.70.00.1
Mg content in liver1.21.33.81.01.3-0.91.30.9-1.2-1.21.01.31.01.01.0-1.01.7-1.01.40.81.10.80.7-2.00.91.1-0.70.4
Mn content in liver3.43.86.01.82.3-1.92.22.0-2.0-2.22.12.52.12.12.0-2.11.5-2.12.32.02.21.81.8-1.61.81.9-0.41.2
Na content in liver0.70.72.5-1.2-1.00.8-0.7-0.70.40.5-0.8-1.0-0.8-0.8-0.30.90.10.8-1.1-0.9-1.3-1.6-1.4-0.5-0.6-0.70.00.3
Rb content in liver0.30.31.70.50.50.00.6-0.10.0-0.00.20.30.20.2-0.5-0.00.50.00.2-0.10.70.70.8-0.70.30.7-1.2-1.3
Se content in liver1.31.52.41.11.3-1.41.01.4-1.2-1.41.31.51.31.31.4-1.50.9-1.51.11.41.31.21.4-0.61.00.40.71.4
Sr content in liver0.10.10.50.20.2-0.00.40.00.2-0.1-0.10.6-0.1-0.10.2-0.1-0.10.0-0.10.20.60.70.60.1-0.3-0.20.40.6
Zn content in liver0.30.30.8-0.2-0.00.3-0.2-0.60.40.5-0.4-0.5-0.4-0.4-0.70.60.60.7-0.2-0.6-0.8-0.7-0.8-0.9-0.6-0.6-0.4-0.8
Bone: minimum diameter2.44.59.42.72.6-1.52.51.8-1.8-2.31.63.11.61.61.8-1.62.0-1.62.31.92.93.03.1-2.21.31.6-1.50.4
Time in familiar zone, hab. session 10.20.21.2-0.10.20.00.3-0.00.00.00.50.00.50.5-0.30.2-0.70.10.2-0.20.20.10.20.60.80.7-1.1-0.9
Time in novel zone, hab. session 11.91.93.9-1.2-1.61.2-1.7-1.31.51.5-1.8-1.2-1.8-1.8-0.90.9-1.01.1-1.6-0.5-1.1-0.7-0.81.2-1.8-1.72.00.8
Total zone transitions, hab. session 10.60.81.70.50.8-1.30.81.1-1.0-0.91.10.71.11.11.2-1.20.6-1.20.71.00.60.20.3-0.21.10.50.81.2
Total locomotion distance, hab. session 10.50.71.40.70.8-1.00.80.9-0.8-0.81.10.91.11.10.7-1.00.0-1.00.70.91.21.11.00.41.10.5-0.30.1
Locomotion velocity, hab. session 11.21.72.81.11.3-1.41.31.4-1.4-1.51.71.31.71.71.2-1.51.0-1.51.21.01.31.21.1-0.71.61.3-0.80.1
Time in familiar zone, hab. session 21.41.55.1-0.7-0.81.7-0.8-1.61.61.3-1.0-0.4-1.0-1.0-1.91.2-1.11.3-0.8-1.60.20.50.40.3-0.80.3-2.0-2.2
Time in novel zone, hab. session 20.70.74.8-0.00.0-0.7-0.00.7-0.8-0.50.2-0.30.10.11.2-0.50.6-0.60.11.0-0.7-0.8-0.7-0.00.2-0.52.12.2
Total zone transitions, hab. session 20.20.21.5-0.5-0.2-0.0-0.50.10.10.2-0.1-0.4-0.1-0.10.2-0.2-0.5-0.1-0.50.2-0.1-0.2-0.10.9-0.2-1.21.20.8
Total locomotion distance, hab. session 20.10.10.70.50.7-0.30.40.3-0.2-0.10.30.10.30.30.1-0.20.4-0.2-0.10.30.10.00.1-0.2-0.4-0.90.3-0.1
Locomotion velocity, hab. session 20.10.10.60.50.7-0.50.40.4-0.2-0.20.40.20.40.40.2-0.30.4-0.3-0.00.50.10.00.1-0.1-0.2-0.80.4-0.0
Novel to familiar place preference ratio0.10.10.30.20.20.00.20.1-0.2-0.1-0.3-0.1-0.3-0.30.20.10.50.10.00.2-0.3-0.3-0.3-0.6-0.3-0.60.20.3
Novelty place preference0.10.10.50.10.10.20.1-0.0-0.1-0.0-0.5-0.1-0.5-0.50.20.10.40.1-0.10.2-0.3-0.2-0.2-0.5-0.4-0.70.50.5
Time in novel zone, NPP test0.10.10.50.20.20.00.20.1-0.2-0.1-0.4-0.1-0.3-0.30.30.00.6-0.00.00.2-0.4-0.3-0.3-0.7-0.3-0.50.40.6
Total zone transitions, NPP test0.71.02.30.50.8-1.50.81.4-1.3-1.11.40.41.41.41.3-1.20.3-1.10.71.00.3-0.10.00.51.30.30.50.8
Total locomotion distance, NPP test1.52.13.41.41.7-1.81.51.8-1.7-1.71.81.41.81.81.6-1.71.0-1.71.41.61.20.80.9-0.41.60.80.10.6
Locomotion velocity, NPP test1.52.13.51.41.6-1.81.51.8-1.7-1.71.91.41.91.91.6-1.71.0-1.81.41.71.30.80.9-0.31.60.80.10.7
Intraocular pressure3.14.57.01.92.0-2.42.42.5-2.6-2.52.22.12.22.22.5-2.62.3-2.52.22.11.71.51.3-2.12.11.40.31.5
Delta distance traveled before/after self-admin0.70.71.8-0.6-0.50.8-0.7-1.01.11.1-1.3-1.0-1.1-1.1-0.81.0-0.51.1-0.6-0.7-0.6-0.8-0.40.3-1.0-0.80.5-0.4
Delta ambulatory time before/after self-admin0.50.61.4-0.6-0.50.6-0.6-0.90.81.0-1.2-1.0-1.0-1.0-0.60.9-0.20.9-0.5-0.6-0.8-0.9-0.70.1-0.8-0.80.8-0.1
Parametrial fat weight0.10.42.10.0-0.20.2-0.3-0.10.10.10.2-0.00.40.4-0.60.2-0.90.00.1-0.30.40.70.50.60.91.1-1.5-1.3
Pavlov. Cond. lever latency0.30.41.00.70.4-0.50.20.5-0.4-0.50.80.90.80.80.3-0.80.2-0.70.50.60.71.00.8-0.20.50.80.00.1
Pavlov. Cond. magazine entry latency2.12.74.4-2.1-2.01.7-2.0-1.41.51.6-1.7-1.9-1.7-1.7-1.11.4-1.91.3-2.1-1.5-1.5-1.3-1.31.9-1.6-1.91.30.6
Pavlov. Cond. change in total contacts0.60.71.4-0.9-0.70.8-0.9-0.60.30.5-1.0-0.9-1.0-1.00.00.80.30.7-0.6-0.5-1.0-1.2-1.1-0.6-1.1-1.00.91.1
Pavlov. Cond. index score1.62.03.1-1.7-1.51.5-1.5-1.31.21.3-1.6-1.7-1.7-1.7-0.81.4-1.11.3-1.7-1.3-1.5-1.6-1.41.0-1.6-1.81.00.7
Pavlov. Cond. latency score1.31.72.7-1.5-1.31.4-1.3-1.21.11.2-1.5-1.6-1.5-1.5-0.81.4-0.91.2-1.5-1.2-1.5-1.6-1.40.8-1.5-1.60.70.4
Pavlov. Cond. lever contacts0.20.21.0-0.4-0.10.4-0.1-0.20.00.1-0.7-0.4-0.7-0.70.20.50.30.4-0.2-0.2-0.3-0.7-0.4-0.4-0.7-1.00.40.6
Pavlov. Cond. magazine entry number4.25.38.22.72.6-2.52.92.3-2.3-2.42.52.52.52.51.7-2.22.3-2.12.82.22.11.91.9-2.12.62.6-1.4-0.4
Pavlov. Cond. intertrial magazine entries0.50.52.00.91.0-0.90.80.8-1.0-0.90.60.60.60.61.0-0.41.4-0.50.90.50.3-0.2-0.2-1.10.60.4-0.10.5
Pavlov. Cond. lever-magazine prob. diff.1.51.83.6-1.6-1.41.3-1.5-1.11.01.1-1.5-1.5-1.5-1.5-0.51.2-1.11.1-1.6-1.0-1.4-1.5-1.31.1-1.6-1.91.31.0
Pavlov. Cond. response bias1.92.33.9-2.0-1.81.8-1.9-1.41.51.4-1.8-1.6-1.8-1.8-1.01.5-1.61.4-1.8-1.5-1.0-1.0-1.01.4-1.6-1.90.80.5
Pavlov. Cond. lever latency0.30.51.4-0.8-0.81.0-0.5-0.70.60.5-0.6-0.6-0.6-0.6-0.70.8-0.50.8-0.6-0.9-0.2-0.3-0.30.5-0.40.2-1.1-1.2
Pavlov. Cond. magazine entry latency1.01.22.2-0.9-0.91.3-1.1-1.41.51.3-1.3-0.8-1.3-1.3-1.51.3-0.81.3-1.0-1.1-0.3-0.4-0.30.5-1.4-1.1-0.1-0.8
Pavlov. Cond. change in total contacts0.61.02.11.11.2-0.91.10.9-0.9-1.11.01.41.01.00.8-1.10.6-1.11.01.01.41.51.3-0.61.00.4-0.30.6
Pavlov. Cond. index score0.10.10.30.20.20.1-0.1-0.20.40.2-0.20.3-0.2-0.2-0.30.1-0.30.10.0-0.00.50.50.60.1-0.3-0.50.30.2
Pavlov. Cond. latency score0.20.20.7-0.1-0.10.4-0.4-0.60.70.5-0.50.1-0.5-0.5-0.70.4-0.50.4-0.2-0.30.30.40.50.2-0.6-0.90.2-0.1
Pavlov. Cond. lever contacts0.60.82.11.11.1-1.30.80.9-0.9-0.80.80.70.80.81.0-1.10.7-1.10.91.20.30.40.3-0.60.60.11.21.4
Pavlov. Cond. magazine entry number0.40.41.10.50.5-0.90.61.0-0.9-0.70.80.20.80.81.0-0.80.3-0.80.50.9-0.1-0.2-0.20.20.70.30.70.7
Pavlov. Cond. intertrial magazine entries0.10.20.90.40.2-0.10.20.4-0.3-0.40.00.60.10.10.6-0.60.0-0.50.00.60.40.50.4-0.1-0.2-0.00.81.0
Pavlov. Cond. lever-magazine prob. diff.0.10.10.30.20.20.1-0.0-0.20.40.2-0.10.3-0.1-0.1-0.30.0-0.40.00.00.00.50.50.60.1-0.2-0.50.30.2
Pavlov. Cond. response bias0.30.40.80.80.9-0.80.60.5-0.6-0.50.50.50.50.50.5-0.70.7-0.70.70.70.20.20.2-0.90.40.20.70.9
Time in closed arm before self-admin0.91.22.11.41.1-1.31.51.3-1.2-1.41.01.31.11.11.3-0.80.6-0.90.90.81.11.21.2-0.41.21.3-0.50.4
Time in closed arm after self-admin1.21.32.31.31.5-1.31.51.4-1.4-1.41.21.31.21.21.4-1.10.9-1.11.51.40.90.40.6-0.81.11.0-0.10.5
Time in open arm before self-admin2.72.95.9-2.0-1.81.6-2.0-1.81.62.1-1.6-2.4-1.7-1.7-1.61.4-0.91.5-1.4-1.3-2.1-1.9-2.10.5-1.8-2.41.5-0.2
Time in open arm after self-admin2.02.24.0-1.5-1.61.1-1.8-1.61.71.9-1.4-1.9-1.4-1.4-1.61.3-1.21.3-1.8-1.2-1.4-1.2-1.31.4-1.6-2.01.3-0.3
Bone: periosteal estimation0.51.15.51.00.70.31.00.3-0.3-0.80.01.70.00.00.4-0.30.3-0.20.70.42.12.22.3-0.90.41.1-1.9-0.3
Bone: periosteal perimeter0.30.62.21.00.60.40.50.0-0.1-0.5-0.41.1-0.4-0.40.20.10.60.20.30.21.21.21.5-1.3-0.30.9-1.4-0.0
Bone: post-yield work0.20.30.8-0.5-0.20.5-0.4-0.40.30.2-0.7-0.3-0.7-0.7-0.20.50.20.6-0.8-0.3-0.4-0.6-0.6-0.5-0.9-0.9-0.00.2
Progressive ratio test 1 active lever presses0.80.91.8-0.9-1.11.4-0.9-1.21.31.2-1.4-0.7-1.2-1.2-1.11.1-1.01.0-0.8-1.0-0.2-0.2-0.30.8-1.0-0.5-0.5-1.0
Progressive ratio test 1 breakpoint0.70.91.8-0.9-1.01.3-0.8-1.21.31.1-1.3-0.6-1.2-1.2-1.11.1-0.91.0-0.8-0.9-0.1-0.1-0.20.7-0.9-0.4-0.6-1.1
Progressive ratio test 1 inactive lever presses0.81.23.3-1.0-0.91.5-0.9-1.51.61.5-1.8-0.6-1.4-1.4-1.51.2-1.01.1-0.7-1.10.00.1-0.00.4-0.8-0.1-0.4-1.1
Progressive ratio test 2 active lever presses1.92.24.4-1.2-1.51.9-1.3-2.01.92.0-2.1-1.4-2.0-2.0-1.91.7-1.01.7-1.4-1.5-1.1-0.9-0.90.1-1.3-0.1-0.3-1.2
Progressive ratio test 2 breakpoint1.82.04.0-1.1-1.41.8-1.2-1.91.91.9-2.0-1.3-1.9-1.9-1.81.7-1.01.6-1.4-1.3-1.0-0.9-0.90.1-1.3-0.1-0.1-1.1
Progressive ratio test 2 inactive lever presses1.11.84.2-1.2-1.32.0-1.2-1.81.91.8-2.0-0.7-1.7-1.7-1.91.4-1.11.4-0.8-1.10.10.20.30.2-0.9-0.1-0.8-1.5
Incentive Sensitization - Responses1.62.24.1-1.3-1.71.3-1.6-1.91.82.0-1.7-1.8-1.7-1.7-1.81.5-1.21.5-1.6-1.3-1.9-1.5-1.50.4-1.00.20.7-0.5
Incentive Sensitization - Breakpoint1.62.03.9-1.3-1.61.2-1.6-1.81.72.0-1.6-1.7-1.6-1.6-1.81.4-1.31.4-1.5-1.2-1.8-1.4-1.40.5-0.90.20.7-0.5
Sum of active levers in priming session hrs 5-60.40.43.00.50.1-0.4-0.00.5-0.6-0.40.5-0.20.80.80.5-0.70.2-0.8-0.10.2-0.6-0.4-0.50.00.91.70.50.8
Progressive ratio0.00.00.2-0.1-0.3-0.2-0.1-0.10.20.2-0.4-0.1-0.3-0.3-0.1-0.0-0.0-0.0-0.30.0-0.3-0.10.10.3-0.1-0.00.50.2
Food seeking constrained by brief footshock0.70.82.5-0.20.00.10.2-0.00.30.10.50.50.80.8-0.8-0.2-1.5-0.10.50.61.31.61.41.21.61.2-1.5-1.4
Seeking ratio, punishment vs. effort0.40.62.5-0.10.20.20.20.2-0.1-0.30.90.60.90.9-0.2-0.3-0.7-0.20.70.31.21.10.90.61.31.2-1.6-1.0
Retroperitoneal fat weight0.21.05.6-1.1-1.01.0-1.0-0.61.00.7-0.2-0.00.00.0-1.10.4-2.40.1-0.3-0.70.81.31.02.30.60.9-1.1-1.1
Reaction time number correct1.12.15.61.21.3-0.91.81.3-1.2-1.61.42.21.31.31.2-1.41.1-1.41.51.62.42.32.1-1.11.00.7-1.10.0
Reaction time mean minus median0.30.81.51.00.7-1.10.51.1-0.8-0.91.10.71.11.11.0-1.2-0.4-1.20.50.80.60.60.50.80.90.90.80.8
Reaction time mean minus median AUC0.10.30.90.50.4-0.50.30.6-0.4-0.50.70.40.60.60.5-0.5-0.6-0.70.30.40.50.50.40.90.60.80.10.1
Reaction time num false alarms0.30.40.9-0.4-0.60.8-0.7-0.70.50.5-0.8-0.5-0.5-0.5-0.70.90.40.8-0.4-0.9-0.4-0.3-0.3-0.6-0.5-0.0-0.9-0.8
Reaction time num false alarms AUC0.50.72.0-0.8-1.01.1-1.1-1.00.80.7-0.9-0.8-0.7-0.7-1.01.1-0.21.1-0.8-1.4-0.5-0.3-0.4-0.1-0.40.1-1.3-1.2
Reaction time trials correct on left1.12.15.61.21.3-0.91.81.3-1.2-1.61.42.21.31.31.2-1.41.1-1.41.51.62.42.32.1-1.11.00.7-1.10.0
Reaction time trials on left1.32.46.01.41.4-1.01.91.4-1.3-1.71.52.41.41.41.3-1.51.2-1.51.61.72.42.42.2-1.11.10.7-1.10.0
Reaction time mean1.32.14.72.22.1-1.91.61.8-1.6-1.61.51.51.51.51.8-1.81.1-1.71.51.40.80.70.5-0.90.80.71.21.2
Reaction time mean AUC0.91.43.71.91.9-1.51.41.5-1.3-1.31.11.21.21.21.5-1.40.9-1.41.21.10.60.40.3-0.70.60.51.01.0
Median of all reaction times1.21.64.02.02.0-1.51.51.5-1.4-1.41.21.41.21.21.5-1.51.2-1.41.41.20.80.70.5-1.10.70.60.70.9
Reaction time omissions1.21.85.12.31.8-1.81.41.7-1.6-1.61.41.31.41.41.5-1.41.6-1.31.41.30.40.10.0-1.00.80.40.10.4
Reaction time false alarm rate1.31.93.8-1.4-1.61.4-1.9-1.51.21.4-1.5-1.9-1.2-1.2-1.41.6-0.71.5-1.4-2.0-1.7-1.5-1.60.5-0.9-0.2-0.3-0.8
Reaction time premature initiation rate3.44.713.4-2.4-2.52.4-2.2-2.43.02.6-1.8-1.4-2.0-2.0-2.91.9-3.71.9-2.4-1.70.10.60.63.6-1.7-1.8-0.3-2.0
Reaction time premature initiations1.22.16.7-1.4-1.31.5-0.9-1.42.01.4-0.90.1-1.1-1.1-1.90.9-2.60.9-1.3-0.61.41.81.72.5-1.0-1.4-0.8-1.7
Std. dev. reaction times0.71.42.91.71.6-1.71.11.5-1.3-1.21.40.91.31.31.5-1.40.5-1.51.21.20.40.30.10.01.00.81.10.9
Reaction time trials completed1.32.46.01.41.4-1.01.91.4-1.3-1.71.52.41.41.41.3-1.51.2-1.51.61.72.42.42.2-1.11.10.7-1.10.0
Reaction time trials AUC1.22.45.61.41.5-1.01.91.4-1.3-1.71.52.31.31.31.2-1.51.4-1.41.61.72.42.32.1-1.31.00.7-1.2-0.0
Run reversals in cocaine runway, females0.10.10.60.70.50.30.6-0.10.10.20.00.10.20.2-0.10.10.3-0.0-0.10.4-0.00.1-0.2-0.7-0.7-0.80.6-0.3
Run reversals in cocaine runway, males0.40.42.90.30.2-0.20.20.4-0.6-0.3-0.0-0.00.70.70.5-0.70.4-0.70.4-0.5-0.5-0.7-0.8-0.61.21.70.20.4
Latency to leave start box in cocaine runway0.10.10.50.10.0-0.5-0.10.5-0.7-0.60.1-0.20.10.10.6-0.10.6-0.2-0.10.3-0.3-0.7-0.50.00.30.1-0.40.2
Latency to leave start box in cocaine runway, F0.30.40.9-0.2-0.60.4-0.5-0.50.30.3-0.9-0.6-0.9-0.9-0.30.90.50.9-0.5-0.6-0.5-0.8-0.5-0.3-0.5-0.7-0.8-0.4
Latency to leave start box in cocaine runway, M0.90.91.80.60.7-1.10.61.3-1.3-1.11.20.31.31.31.3-1.30.4-1.30.41.20.0-0.2-0.30.20.90.80.60.8
Std. dev. time between licks in bursts1.11.53.4-1.4-1.51.0-1.6-1.00.91.1-1.3-1.7-1.3-1.3-0.71.1-0.81.1-1.4-0.9-1.9-1.8-1.80.8-1.1-1.00.80.3
Total sessions with >9 infusions0.60.81.9-0.8-0.81.4-0.7-1.11.31.2-1.2-0.5-1.1-1.1-1.10.8-1.40.8-0.8-0.70.10.3-0.00.8-0.6-0.0-0.1-0.8
Short access day 1 total inactive lever presses0.20.30.8-0.6-0.50.7-0.5-0.60.30.5-0.8-0.7-0.7-0.7-0.30.90.10.7-0.4-0.4-0.7-0.5-0.8-0.4-0.3-0.1-0.4-0.1
Short access day 10 total inactive lever presses0.30.72.10.70.7-0.80.60.6-0.5-0.60.61.11.01.00.4-0.90.4-0.81.11.01.31.41.4-0.50.60.4-0.10.2
Short access day 1 total infusions0.70.91.9-0.9-0.91.1-0.8-1.11.21.3-1.4-1.0-1.2-1.2-1.01.1-1.30.9-0.9-0.7-0.6-0.2-0.60.9-1.0-0.60.4-0.4
Short access day 10 total infusions0.20.30.9-0.1-0.41.0-0.2-0.50.60.4-0.70.3-0.6-0.6-0.60.2-0.30.10.1-0.00.70.60.6-0.1-0.10.9-0.8-0.7
Short access total infusions0.70.92.3-1.0-1.11.5-0.9-1.21.21.3-1.5-0.9-1.3-1.3-1.10.9-1.00.8-0.7-0.7-0.3-0.2-0.50.7-0.70.0-0.0-0.6
Short access day 1 locomotion0.80.92.2-0.4-0.41.4-0.2-1.31.51.2-1.3-0.1-1.0-1.0-1.31.2-1.31.2-0.6-1.00.50.80.60.4-1.1-0.8-0.5-1.2
Short access day 10 total locomotion2.44.48.22.22.4-1.42.52.0-1.9-2.21.92.92.12.11.8-2.21.8-2.22.62.22.82.42.4-1.91.91.7-0.80.6
Short access total locomotion0.50.62.70.70.80.51.00.1-0.0-0.40.11.30.20.20.0-0.30.2-0.30.70.41.71.41.3-0.80.40.6-1.3-0.7
One hour access (0.3 mA shock)1.31.52.9-1.3-1.41.6-1.3-1.71.61.7-1.5-1.3-1.4-1.4-1.61.3-0.81.3-1.3-1.2-0.9-1.0-0.8-0.0-0.90.3-0.2-0.9
Compulsive drug intake1.01.26.0-0.9-0.8-0.6-0.7-0.40.10.7-0.4-1.7-0.4-0.4-0.10.60.20.6-0.7-0.5-2.3-2.3-2.4-0.2-0.3-0.81.91.2
One hour access (shock baseline)0.50.72.5-0.4-0.51.4-0.4-1.01.10.7-0.80.3-0.8-0.8-1.20.6-0.70.6-0.4-0.61.00.91.1-0.0-0.30.9-1.6-1.4
Social response proportion4.45.09.63.12.5-2.92.12.7-2.7-2.62.62.12.42.42.6-2.52.8-2.52.22.61.30.61.0-2.11.60.60.71.3
Social responses0.81.14.02.01.5-1.40.81.1-0.9-1.01.21.31.01.00.8-1.11.1-1.10.81.20.80.50.7-1.00.1-1.00.50.3
Social time0.81.03.01.71.5-1.31.21.1-1.0-1.11.11.31.11.10.9-0.90.8-0.80.81.31.00.90.8-0.60.4-0.4-0.10.1
Soleus weight0.82.34.5-1.6-1.41.9-1.2-1.31.61.1-1.6-0.6-1.6-1.6-1.41.7-2.11.6-1.6-1.40.71.00.92.0-1.1-1.7-1.9-1.8
Bone: stiffness0.10.10.50.0-0.10.00.10.2-0.2-0.40.10.60.10.10.4-0.1-0.1-0.1-0.20.40.60.60.7-0.1-0.10.0-0.40.4
Tibialis anterior weight1.34.57.82.32.6-2.82.62.7-2.6-2.52.41.92.42.42.4-2.22.0-2.22.22.71.51.01.1-1.12.01.1-0.10.6
Time to tail flick, vehicle, before self-admin0.30.41.6-0.2-0.60.7-0.6-0.60.60.3-0.50.0-0.7-0.7-0.70.5-0.40.5-0.4-0.50.70.70.70.4-0.2-0.2-1.3-0.9
Time to tail flick, vehicle, after self-admin0.70.93.5-0.9-0.90.9-0.8-0.90.30.6-0.8-1.2-0.7-0.7-0.60.80.20.8-0.4-1.1-1.8-1.9-1.8-1.3-0.21.1-0.3-0.2
Time to tail flick, test, before self-admin1.11.23.91.01.1-0.70.80.8-0.6-0.71.01.41.11.10.4-1.1-0.1-1.11.00.81.61.71.9-0.01.42.0-0.30.2
Time to tail flick, test, after self-admin1.01.02.61.41.3-1.21.41.0-1.2-1.00.60.50.70.71.2-0.71.5-0.81.11.40.1-0.6-0.4-1.60.50.30.91.1
Delta time to tail flick, vehicle, before/after SA0.50.52.6-0.2-0.00.00.2-0.1-0.30.1-0.2-0.6-0.1-0.10.10.20.90.20.0-0.3-1.6-1.6-1.6-1.6-0.00.90.40.4
Delta time to tail flick, test, before/after SA0.50.52.20.30.2-0.30.50.3-0.6-0.3-0.3-0.4-0.2-0.20.60.21.30.20.10.4-0.7-1.5-1.4-1.1-0.7-1.30.50.5
Tibia length0.20.54.00.30.00.30.90.2-0.5-0.60.20.60.20.20.20.10.60.00.70.20.91.00.7-1.00.61.3-2.0-0.6
Ambulatory time before self-admin0.40.64.4-0.6-1.20.2-1.3-0.20.40.40.1-0.8-0.3-0.3-0.40.2-1.60.1-1.1-0.5-0.8-0.2-0.42.10.0-0.40.30.1
Ambulatory time after self-admin0.60.72.3-0.6-0.90.2-1.1-0.60.70.9-0.7-1.2-0.9-0.9-0.60.6-1.10.5-1.3-0.5-1.2-0.5-0.71.5-0.5-1.00.90.1
Bone: tissue strength0.30.31.20.80.5-0.20.2-0.0-0.0-0.0-0.1-0.1-0.1-0.1-0.00.50.40.5-0.1-0.1-0.7-0.8-0.7-0.5-1.0-1.1-0.1-0.6
Total heroin consumption0.91.12.21.21.0-1.20.71.0-1.4-1.01.20.01.11.11.1-0.91.5-1.00.30.5-1.3-1.0-0.9-1.41.01.30.61.1
Bone: trabecular number0.20.42.1-0.2-0.2-0.3-0.4-0.1-0.10.2-0.2-0.6-0.2-0.20.20.20.70.20.3-0.1-1.1-1.5-1.3-0.7-0.1-0.11.20.9
Bone: trabecular spacing2.33.06.21.51.4-1.51.81.6-1.4-1.72.12.22.12.11.2-1.90.4-1.91.61.82.52.52.5-0.11.81.8-1.00.1
Bone: trabecular thickness1.72.14.21.51.6-1.61.71.7-2.0-1.81.31.31.31.32.0-1.32.0-1.41.71.10.70.40.4-1.91.61.3-0.11.2
Bone: trabecular tissue density0.40.61.90.61.1-1.11.11.0-0.8-0.81.40.51.41.40.7-0.90.0-0.90.30.80.2-0.1-0.30.60.60.00.0-0.1
Water consumed over 24 hours0.81.02.4-1.4-1.20.7-1.1-1.21.21.4-0.7-1.4-0.7-0.7-1.61.1-1.21.1-0.7-0.6-0.9-1.1-0.91.1-0.4-0.40.2-1.1
Number of responses in last shaping day0.30.30.7-0.9-0.70.9-0.5-0.60.70.6-0.4-0.1-0.2-0.2-0.70.3-0.80.2-0.2-0.30.60.80.30.5-0.3-0.5-0.3-0.4