Hub : Genes

Arhgef19

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain alternative polyA XM_008764270.4 0.07 0.05 2.1e-03 -0 0.02 0.02 0 5.8e-01 4.1e-03 3.0e-03 1.2e-01
2 Brain alternative polyA XM_008764270.4 0.07 0.05 2.6e-03 -0 0.02 0.02 0 6.3e-01 6.2e-03 3.3e-03 1.7e-01
3 Liver mRNA stability Arhgef19 0.03 0.02 9.8e-03 0.01 0 0 0 6.1e-02 3.0e-01 3.3e-01 3.7e-01
4 Brain alternative polyA NM_001108692.1 0.06 0.05 8.1e-03 -0 0.01 0.01 -0 6.4e-01 6.7e-02 1.5e-02 8.8e-01
5 OFC alternative TSS XM_008764270.4 0.21 0.13 4.5e-03 0.07 0.04 0.04 0.08 9.3e-03 3.1e-02 5.1e-02 6.5e-03
6 OFC alternative TSS NM_001108692.1 0.26 0.15 2.3e-03 0.09 0.05 0.04 0.1 3.3e-03 2.0e-02 3.4e-02 2.8e-03
7 OFC alternative TSS XM_008764270.4 0.27 0.15 1.9e-03 0.09 0.06 0.04 0.1 3.7e-03 2.0e-02 5.2e-02 2.9e-03
8 Liver gene expression Arhgef19 0.55 0.14 0.0e+00 0.4 0.44 0.47 0.43 5.7e-48 5.7e-53 1.5e-57 1.2e-51
9 NAcc gene expression Arhgef19 0.04 0.03 4.7e-04 0.01 0.01 0.01 0.01 7.3e-03 4.2e-03 2.8e-03 4.4e-03
10 Brain gene expression Arhgef19 0.04 0.03 8.2e-03 0.02 0.02 0.01 0.02 4.4e-03 8.1e-03 2.7e-02 9.3e-03
11 Adipose gene expression Arhgef19 0.03 0.02 5.8e-03 0.01 0 0 -0 5.1e-02 3.0e-01 3.4e-01 8.3e-01
12 NAcc alternative polyA NM_001108692.1 0.04 0.02 1.1e-04 0.03 0.03 0.03 0.03 1.0e-04 1.6e-05 6.1e-05 1.2e-05
13 NAcc isoform ratio NM_001108692.1 0.05 0.03 8.8e-05 0.03 0.03 0.02 0.03 3.0e-05 1.9e-05 4.1e-04 1.9e-05
14 NAcc alternative polyA NM_001108692.1 0.04 0.02 2.6e-04 0.02 0.03 0.02 0.03 2.4e-04 4.1e-05 2.3e-04 9.0e-05
15 NAcc alternative polyA XM_008764270.4 0.04 0.02 1.5e-04 0.03 0.03 0.02 0.03 1.0e-04 2.9e-05 2.5e-04 4.4e-05
16 NAcc alternative polyA XM_008764270.4 0.04 0.02 1.2e-04 0.02 0.03 0.02 0.03 1.3e-04 2.3e-05 1.2e-04 2.9e-05
17 PL gene expression Arhgef19 0.04 0.02 1.1e-03 0 0.02 0.01 0.01 1.9e-01 1.7e-03 3.8e-02 2.1e-02
18 Liver alternative polyA XM_008764270.4 0.07 0.05 3.3e-05 0.01 0.02 0.01 0.01 1.0e-02 2.5e-03 5.7e-02 4.4e-02
19 Liver alternative polyA NM_001108692.1 0.07 0.04 2.5e-05 0.01 0.02 0.01 0.01 8.8e-03 2.4e-03 4.6e-02 4.2e-02
20 Liver alternative polyA NM_001108692.1 0.07 0.04 2.6e-05 0.01 0.02 0.01 0.01 8.6e-03 3.0e-03 5.5e-02 4.1e-02
21 Liver alternative polyA XM_008764270.4 0.07 0.05 4.2e-05 0.01 0.02 0.01 0.01 1.4e-02 3.2e-03 5.9e-02 6.6e-02
22 Liver isoform ratio NM_001108692.1 0.07 0.07 3.0e-04 0 0.01 0.02 0 1.0e-01 4.4e-02 6.4e-03 3.1e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density1.32.58.4-1.8-1.7-2.91.52.5-2.52.52.01.31.7-1.01.2-0.8-0.50.70.50.2-1.01.01.0-1.0-1.5
Area under the delay curve0.81.28.0-1.8-1.9-1.02.80.3-0.20.21.2-0.41.5-0.50.3-0.6-0.70.80.8-1.10.9-0.9-0.90.90.8
BMI with tail0.51.63.80.90.60.8-0.3-1.71.7-1.7-1.5-1.8-1.72.0-1.5-0.00.20.10.2-0.21.3-1.3-1.31.31.6
BMI without tail0.31.55.51.41.20.6-1.4-1.61.5-1.4-1.9-1.4-2.32.2-0.80.50.8-0.5-0.40.80.5-0.4-0.50.41.1
Body weight0.20.93.0-0.8-1.1-0.71.3-0.60.7-0.7-0.20.2-0.51.2-0.8-0.6-0.40.80.8-0.61.4-1.4-1.41.41.7
Weight adjusted by age0.31.06.3-0.7-1.0-0.30.9-0.90.9-0.8-0.8-0.2-0.71.3-1.3-1.0-0.60.80.90.10.9-0.9-0.90.92.5
Bone surface1.32.69.3-2.0-1.9-3.01.82.5-2.52.51.91.51.5-1.01.2-1.1-0.70.90.70.3-1.00.90.9-0.9-0.9
Bone volume1.73.410.9-2.1-2.0-3.31.92.8-2.82.82.51.82.2-1.71.2-1.5-1.21.31.1-0.3-0.70.70.7-0.7-1.3
Breakpoint value in progressive ratio session0.10.22.4-0.2-0.10.30.30.0-0.00.0-0.2-1.50.10.20.50.50.4-0.5-0.50.2-0.30.30.3-0.3-0.9
Number of licking bursts0.51.63.91.31.6-1.0-1.61.8-2.02.01.01.00.8-1.80.5-0.5-0.40.20.10.5-1.41.41.4-1.4-1.2
Context. condit. distance diff. score1.41.75.7-0.20.2-1.0-1.61.8-1.91.81.41.41.0-1.90.7-0.6-0.50.30.20.2-1.41.41.4-1.4-2.4
Locomotion velocity, session 11.11.36.6-0.7-0.5-0.2-0.21.4-1.51.41.51.51.9-2.60.4-0.7-1.00.60.5-0.6-0.80.80.8-0.8-1.2
Locomotion distance, session 10.40.64.20.00.20.10.70.7-0.60.51.00.11.7-2.11.00.1-0.3-0.1-0.1-0.5-0.60.60.6-0.5-0.3
Locomotion velocity, session 20.20.32.20.20.31.50.0-0.30.2-0.20.2-0.20.8-1.20.40.50.0-0.4-0.4-0.5-0.20.20.2-0.2-0.8
Locomotion distance, session 20.71.03.0-0.1-0.21.01.6-0.91.0-1.10.4-0.30.9-1.0-0.7-0.6-0.90.80.8-1.71.4-1.4-1.41.40.6
Locomotion velocity, session 30.30.30.90.70.80.3-0.80.0-0.10.1-0.1-0.9-0.2-0.30.30.50.4-0.5-0.50.4-0.70.70.7-0.7-0.9
Locomotion distance, session 30.80.95.31.61.9-0.3-2.30.7-0.70.60.70.90.5-1.30.0-0.6-0.60.40.4-0.1-0.60.50.6-0.5-1.1
Stereotopy head waving bouts, day 31.11.36.8-1.0-1.31.42.1-1.51.4-1.4-0.8-2.6-0.11.1-0.30.70.5-0.5-0.4-0.40.8-0.8-0.80.80.7
Stereotopy head waving duration, day 31.11.48.1-0.2-0.51.61.3-1.51.3-1.3-1.3-2.9-0.71.30.21.51.3-1.3-1.30.40.1-0.1-0.10.10.6
Locomotion velocity, session 71.11.26.41.31.6-0.5-2.50.8-0.80.8-0.00.9-0.8-0.20.4-0.00.3-0.3-0.41.3-1.51.41.4-1.5-1.6
Locomotion distance, session 70.81.04.50.30.7-1.1-1.21.4-1.31.30.92.10.6-1.30.5-1.0-0.90.80.70.3-0.80.80.8-0.8-0.7
Stereotopy head waving bouts, day 70.30.31.40.10.1-0.70.30.6-0.60.60.1-1.20.2-0.20.90.30.5-0.4-0.50.6-0.80.80.8-0.8-0.2
Stereotopy head waving duration, day 70.60.71.5-0.2-0.1-0.90.11.2-1.21.20.5-1.10.6-0.61.00.30.4-0.4-0.50.6-1.11.11.1-1.1-1.1
Locomotion velocity, session 80.70.93.00.40.50.6-0.9-0.00.0-0.00.91.20.9-1.7-0.8-1.1-1.41.11.1-1.50.7-0.7-0.70.7-1.0
Locomotion distance, session 81.11.76.2-1.1-0.9-1.40.21.7-1.71.62.01.41.7-2.50.5-1.1-1.21.00.9-0.8-0.60.50.6-0.5-1.6
Degree of sensitization distance0.30.31.2-0.9-0.90.20.9-0.60.5-0.5-0.60.3-0.50.8-0.2-0.2-0.10.20.20.10.4-0.4-0.40.41.1
Degree of sensitization stereotypy0.50.51.70.20.2-1.3-0.10.9-0.90.90.2-0.5-0.0-0.21.10.30.5-0.4-0.50.9-1.01.01.0-1.0-0.0
Conditioned locomotion1.41.74.71.41.41.70.5-1.51.5-1.5-1.2-1.7-0.70.71.22.21.8-1.9-1.90.8-0.40.50.5-0.50.5
Cocaine response after cond. corrected3.65.411.72.41.92.6-0.8-3.43.4-3.3-2.6-1.5-2.52.8-2.7-0.2-0.10.40.6-0.72.6-2.5-2.52.53.3
Cocaine response after cond. not corrected3.24.610.72.82.52.5-1.1-3.23.0-3.0-2.9-1.8-2.62.9-1.80.50.6-0.4-0.20.11.7-1.6-1.71.63.3
Cocaine response before conditioning1.82.25.1-0.20.1-1.20.22.0-2.02.00.8-0.01.1-1.32.20.80.8-1.0-1.11.4-2.22.22.2-2.2-1.2
Saline control response0.91.33.1-1.0-1.1-0.81.40.3-0.40.4-0.3-1.0-0.21.01.71.61.7-1.5-1.61.5-1.21.21.2-1.20.6
Bone: connectivity density1.01.56.0-1.6-1.6-2.41.51.8-1.91.90.90.50.7-0.11.2-0.30.10.1-0.01.0-1.21.21.2-1.2-0.2
Bone: cortical apparent density1.11.73.61.61.61.3-0.7-0.70.6-0.6-1.5-0.7-1.10.61.01.91.8-1.9-1.91.6-1.21.31.3-1.30.8
Bone: cortical area1.93.08.6-2.1-1.9-2.91.72.7-2.62.61.80.71.4-1.42.3-0.20.00.0-0.20.8-1.71.71.7-1.7-1.3
Bone: cortical porosity0.91.03.00.50.40.61.7-1.31.3-1.3-0.8-1.70.20.81.01.41.1-1.1-1.10.30.2-0.1-0.10.11.6
Bone: cortical porosity1.11.24.30.40.20.91.8-1.61.7-1.7-0.7-1.20.40.5-0.20.50.2-0.2-0.2-0.81.2-1.2-1.21.22.1
Bone: cortical thickness2.43.912.0-0.7-0.5-2.11.22.0-1.92.00.5-1.20.4-0.53.51.82.0-1.9-2.12.3-2.92.92.9-2.9-1.1
Bone: cortical thickness1.62.05.8-1.8-1.5-2.01.41.9-1.81.81.40.51.2-1.02.40.10.2-0.2-0.30.7-1.41.41.4-1.4-1.6
Bone: cortical tissue density1.11.73.41.71.81.5-1.0-0.80.7-0.7-1.6-0.7-1.20.70.81.81.7-1.8-1.81.6-1.11.11.1-1.10.9
Condit. Reinf. active minus inactive responses0.20.20.90.50.60.20.30.4-0.30.30.4-0.80.9-0.70.2-0.2-0.30.10.1-0.3-0.10.10.1-0.1-0.6
Condit. Reinf. active-inactive response ratio0.10.11.10.0-0.00.00.70.1-0.0-0.00.2-1.10.8-0.0-0.4-0.1-0.10.10.1-0.40.2-0.2-0.20.20.0
Condit. Reinf. active responses0.30.41.30.70.90.3-0.30.7-0.70.70.4-0.60.8-1.00.70.1-0.1-0.2-0.20.2-0.70.70.7-0.7-1.1
Condit. Reinf. inactive responses0.10.20.50.30.40.5-0.60.1-0.20.2-0.20.1-0.3-0.50.70.10.1-0.2-0.20.4-0.60.60.6-0.6-0.7
Incentive salience index mean0.40.52.20.10.3-0.20.51.0-0.90.80.8-0.51.5-1.40.7-0.2-0.30.10.0-0.2-0.50.50.6-0.5-0.7
Condit. Reinf. lever presses0.60.93.10.00.2-0.7-0.01.6-1.51.41.00.51.4-1.71.1-0.1-0.2-0.0-0.10.1-1.11.11.1-1.1-0.8
Condit. Reinf. active minus inactive responses0.10.10.60.50.5-0.3-0.8-0.20.2-0.2-0.2-0.1-0.50.6-0.6-0.00.10.00.10.10.1-0.1-0.20.1-0.4
Condit. Reinf. active-inactive response ratio0.40.72.11.41.40.8-1.2-1.00.9-0.9-1.1-1.0-1.11.1-0.70.40.4-0.4-0.30.30.3-0.3-0.30.30.3
Condit. Reinf. active responses0.30.51.4-0.8-0.7-1.20.20.9-0.80.81.11.00.9-0.60.3-0.4-0.40.40.4-0.3-0.20.20.2-0.2-1.1
Condit. Reinf. inactive responses1.42.16.4-2.5-2.4-1.82.31.8-1.71.61.91.12.1-1.51.6-0.3-0.40.30.2-0.3-0.70.70.7-0.7-0.9
Condit. Reinf. lever presses1.01.53.5-1.1-1.0-1.90.61.7-1.61.51.81.71.7-1.60.2-1.3-1.31.21.1-0.6-0.20.20.2-0.2-0.6
Condit. Reinf. lever reinforcers received0.40.52.0-0.7-0.6-1.4-0.00.8-0.70.71.11.40.8-0.5-0.0-0.7-0.70.70.7-0.50.1-0.1-0.10.1-0.8
Conditioned reinforcement - actives0.10.44.40.30.30.00.20.0-0.10.1-0.3-2.10.10.70.50.50.6-0.6-0.60.6-0.50.50.5-0.5-0.2
Conditioned reinforcement - inactives0.20.63.30.90.70.9-0.4-1.11.0-1.0-0.9-1.8-0.70.9-0.70.20.3-0.2-0.1-0.10.6-0.6-0.60.60.7
Conditioned locomotion0.10.23.5-0.2-0.3-0.00.5-0.10.0-0.0-0.1-1.90.30.5-0.30.10.1-0.1-0.10.1-0.00.00.0-0.00.4
Patch foraging indifference point 0 sec1.74.912.10.40.4-0.20.60.1-0.10.1-1.6-2.7-1.31.12.93.43.5-3.4-3.43.1-2.62.72.6-2.60.6
Patch foraging indifference point AUC1.74.111.8-1.0-0.6-3.0-0.33.4-3.43.42.22.51.7-2.51.8-1.1-0.80.70.50.8-2.02.02.0-2.0-1.2
Delay disc. indifference point, 0s delay2.32.67.7-1.8-1.6-1.12.31.2-1.21.12.61.02.8-2.30.5-1.7-1.91.71.6-2.00.7-0.8-0.70.8-1.0
Delay disc. indifference point, 16s delay0.71.03.7-1.6-1.6-0.81.90.2-0.10.01.0-0.11.2-0.40.0-0.5-0.70.80.8-1.21.0-1.0-1.01.11.1
Delay disc. indifference point, 2s delay0.70.86.9-1.4-1.5-0.92.60.10.0-0.00.7-0.20.90.00.6-0.4-0.40.60.5-0.60.6-0.6-0.60.60.9
Delay disc. indifference point, 24s delay0.10.21.5-0.2-0.20.01.2-0.40.4-0.4-0.2-0.90.10.50.50.70.6-0.5-0.60.10.1-0.1-0.10.10.2
Delay disc. indifference point, 4s delay0.70.75.0-1.0-1.2-0.22.2-0.60.6-0.60.1-0.70.50.5-0.0-0.2-0.20.40.4-0.71.0-0.9-1.01.01.1
Delay disc. indifference point, 8s delay0.91.66.1-1.5-1.5-0.72.5-0.0-0.00.01.3-0.41.5-0.7-0.5-1.2-1.31.41.4-1.71.4-1.4-1.41.40.9
Indifference point function ln k1.23.79.81.00.62.90.8-3.13.1-3.1-1.7-1.4-1.01.2-2.10.50.1-0.10.1-1.52.4-2.4-2.42.42.2
Indifference point function log k1.23.79.81.00.62.90.8-3.13.1-3.1-1.7-1.4-1.01.2-2.10.50.1-0.10.1-1.52.4-2.4-2.42.42.2
Patch foraging total patch changes 0 sec1.54.411.00.40.4-0.20.50.1-0.10.1-1.4-2.6-1.20.92.83.33.3-3.2-3.32.9-2.52.52.5-2.50.7
Patch foraging total patch changes 12 sec3.95.312.9-1.5-1.2-2.80.63.1-3.13.11.30.21.1-1.33.61.21.5-1.5-1.72.2-3.23.23.2-3.2-1.7
Patch foraging total patch changes 18 sec4.410.427.3-2.2-1.9-2.71.03.3-3.43.50.6-0.70.2-0.85.22.73.0-3.1-3.34.1-4.84.84.8-4.8-1.4
Patch foraging total patch changes 24 sec1.75.712.2-2.9-2.6-3.51.93.5-3.53.51.71.11.2-1.53.20.40.8-0.7-0.92.1-2.92.92.9-2.9-0.6
Patch foraging total patch changes 6 sec2.74.610.7-1.0-0.8-2.30.92.4-2.42.40.3-0.50.2-0.43.21.62.0-1.9-2.12.9-3.33.33.3-3.20.1
Patch foraging time to switch 0 sec0.20.82.71.00.91.1-0.9-1.31.3-1.3-1.4-0.7-1.21.7-0.30.80.8-0.7-0.70.60.2-0.2-0.20.10.0
Patch foraging water rate 0 sec0.41.63.8-0.8-0.6-1.50.61.9-1.92.00.9-0.10.8-1.31.80.20.3-0.4-0.61.0-1.71.71.7-1.7-0.4
Patch foraging water rate 12 sec0.20.83.9-1.9-2.0-1.11.60.8-0.90.90.7-1.10.6-0.51.0-0.1-0.00.10.0-0.0-0.30.30.3-0.30.4
Patch foraging water rate 18 sec0.51.23.8-1.8-1.9-0.51.50.2-0.20.30.80.10.9-0.5-1.0-1.3-1.31.31.3-1.41.1-1.1-1.11.10.9
Patch foraging water rate 24 sec0.10.20.80.50.50.6-0.4-0.70.6-0.6-0.6-0.8-0.50.1-0.1-0.1-0.10.10.1-0.10.4-0.3-0.30.30.9
Patch foraging water rate 6 sec0.50.83.3-1.0-1.1-1.01.80.6-0.60.70.1-1.40.3-0.11.40.40.6-0.5-0.60.7-0.80.80.8-0.81.0
Seeking ratio, delayed vs. immediate footshock0.81.22.8-0.3-0.3-1.2-0.40.7-0.60.61.11.20.7-0.9-1.1-1.7-1.61.71.7-1.51.1-1.1-1.11.10.2
Distance traveled before self-admin1.22.66.5-1.5-1.2-1.9-0.52.4-2.52.61.2-0.40.5-1.21.90.10.3-0.4-0.51.1-2.12.12.1-2.1-2.2
Distance traveled after self-admin1.12.04.70.20.30.1-0.60.4-0.60.6-1.0-1.0-1.20.61.61.81.9-1.9-2.02.2-2.02.02.0-2.0-0.0
Extensor digitorum longus weight0.10.30.9-0.4-0.4-0.90.10.8-0.90.90.60.40.5-0.5-0.1-0.4-0.20.30.2-0.0-0.30.30.3-0.3-0.4
Bone: elastic displacement2.12.66.11.11.30.2-0.40.0-0.20.2-1.1-0.9-0.80.52.22.22.3-2.3-2.42.5-2.22.22.2-2.20.9
Bone: elastic work1.82.47.0-0.20.0-0.90.51.0-1.11.2-0.1-0.80.1-0.12.61.71.8-1.8-1.92.2-2.32.32.3-2.3-0.1
Bone: endosteal estimation2.15.212.8-2.5-2.5-1.60.80.6-0.50.51.82.51.0-1.0-2.6-3.6-3.33.53.5-2.62.4-2.5-2.52.50.4
Bone: endosteal perimeter1.12.66.0-1.0-1.2-0.50.60.00.1-0.21.11.70.6-0.8-2.1-2.4-2.32.42.5-2.22.0-2.0-2.02.00.5
Epididymis fat weight0.31.43.6-0.6-0.8-0.20.3-0.20.4-0.40.8-0.10.4-0.0-1.7-1.6-1.51.71.7-1.91.7-1.7-1.71.7-0.7
Delta time in closed arm before/after self-admin6.05.611.1-2.5-2.6-1.11.40.3-0.10.12.13.21.4-1.1-1.9-3.1-3.13.33.3-3.32.9-2.9-2.92.91.0
Delta time in open arm before/after self-admin0.91.14.91.81.82.2-1.1-1.41.4-1.4-1.1-0.9-0.6-0.0-1.00.40.1-0.4-0.2-0.40.6-0.5-0.50.50.1
Diff in mean of infusions in LGA sessions0.00.00.2-0.2-0.20.0-0.0-0.20.1-0.1-0.30.2-0.30.4-0.00.10.2-0.1-0.10.4-0.10.10.1-0.1-0.2
Delay discount exponential model param0.71.06.71.51.60.9-2.6-0.0-0.10.1-0.80.5-1.10.0-0.20.50.5-0.7-0.61.0-0.90.90.9-0.9-1.0
Extinction: sum of active levers before priming1.01.513.3-1.7-1.81.23.7-0.80.7-0.7-0.1-2.21.2-0.30.30.60.3-0.5-0.5-0.40.3-0.3-0.30.31.7
Active lever presses in extinction session 61.01.02.4-0.1-0.11.50.7-1.31.3-1.3-0.3-0.10.10.1-1.6-0.6-0.80.70.8-1.11.4-1.4-1.41.40.9
Bone: final force1.62.57.1-2.5-2.4-2.71.92.2-2.22.21.60.91.5-0.91.8-0.4-0.10.30.10.6-1.31.31.3-1.3-1.2
Bone: final moment1.62.56.7-2.5-2.4-2.61.82.2-2.22.21.80.91.5-1.21.6-0.6-0.40.40.30.4-1.21.21.2-1.2-1.4
Food consumed during 24 hour testing period0.40.92.2-0.1-0.2-1.30.30.8-0.80.81.01.20.7-0.6-1.2-1.5-1.31.41.4-1.00.7-0.7-0.70.7-0.0
Glucose0.10.20.8-0.2-0.3-0.00.3-0.1-0.00.0-0.3-0.8-0.40.90.20.30.5-0.4-0.40.6-0.30.30.3-0.30.1
Heart weight1.32.16.2-2.5-2.5-2.41.82.1-2.22.21.1-0.61.2-0.21.0-0.30.10.10.00.8-1.21.21.2-1.10.0
Delay discount hyperbolic model param0.81.07.71.61.70.9-2.8-0.0-0.10.1-0.90.5-1.20.1-0.30.40.5-0.6-0.61.0-0.90.90.9-0.9-0.9
Intermittent access intake day 1-15 change0.21.13.31.61.40.6-0.9-0.90.9-0.8-1.5-1.3-1.81.5-0.11.01.2-1.1-1.11.3-0.50.60.5-0.60.4
Intermittent access intake escalation0.21.13.51.81.60.8-1.2-1.11.0-1.0-1.5-1.0-1.91.4-0.30.81.0-0.9-0.81.1-0.30.30.3-0.40.3
Intermittent access intake escalation 20.30.42.11.41.30.5-1.0-0.60.7-0.7-0.8-0.1-1.00.7-0.50.30.4-0.4-0.30.5-0.10.10.1-0.10.3
Intermitt. access day 1 inactive lever presses0.00.31.51.11.20.2-1.00.2-0.30.30.3-0.50.2-0.6-0.10.0-0.1-0.1-0.1-0.2-0.20.20.2-0.2-0.7
Intermitt. access day 15 inactive lever presses0.10.30.9-0.4-0.3-0.30.30.5-0.30.30.7-0.50.8-0.7-0.4-0.9-0.90.90.9-0.70.4-0.4-0.40.4-0.2
Intermitt. access escalation Index0.20.62.2-0.2-0.1-0.50.50.6-0.70.70.1-0.60.7-0.31.50.80.8-0.8-0.90.9-1.01.01.0-1.00.1
Intermittent access day 1 total infusions0.30.83.31.81.81.3-1.0-0.80.8-0.8-0.3-0.20.4-0.0-1.2-0.3-0.50.30.4-0.80.8-0.8-0.80.80.6
Intermittent access day 15 total infusions0.82.07.42.72.61.6-1.7-1.71.7-1.7-1.4-1.3-1.21.1-1.9-0.1-0.10.10.3-0.31.0-1.0-1.01.01.2
Intermittent access terminal intake (last 3 days)1.22.011.03.33.31.6-2.6-1.41.4-1.4-1.3-0.3-1.20.9-1.60.10.1-0.2-0.00.10.5-0.5-0.50.50.7
Intermittent access total infusions2.12.59.63.13.02.2-2.4-1.81.8-1.8-1.3-0.8-0.90.8-2.0-0.1-0.30.20.3-0.61.2-1.2-1.21.21.2
Intermittent access day 1 locomotion0.40.73.21.81.81.2-1.4-0.90.9-0.9-0.7-0.3-0.50.4-1.10.1-0.0-0.00.0-0.20.5-0.5-0.50.50.6
Intermittent access day 15 total locomotion0.20.92.21.41.20.8-0.9-1.01.1-1.1-1.00.2-1.11.2-1.30.00.10.00.1-0.10.9-0.9-0.90.91.5
Intermittent access total locomotion2.02.45.72.42.21.8-1.5-1.91.9-1.9-2.3-1.0-2.12.1-1.01.21.2-1.1-1.01.00.3-0.2-0.20.21.8
Intermittent access standard deviation0.10.74.81.92.00.6-2.2-0.10.0-0.00.1-0.70.2-0.5-0.7-0.4-0.40.20.3-0.50.0-0.0-0.00.0-1.3
Left kidney weight0.54.213.8-3.7-3.7-3.32.82.8-2.72.72.51.12.4-1.40.8-1.5-1.21.41.3-0.7-0.20.20.2-0.2-0.3
Right kidney weight0.42.88.1-2.8-2.8-2.62.42.1-1.91.92.11.22.1-1.20.3-1.6-1.41.51.4-1.00.3-0.3-0.30.30.2
Cocaine induced anxiety0.51.32.6-1.1-1.1-1.20.71.0-1.11.20.1-1.3-0.20.41.30.81.0-0.9-1.01.6-1.61.61.6-1.6-0.8
Post-drug Anxiety2.12.36.5-1.4-1.3-2.51.22.3-2.42.41.20.20.8-0.41.4-0.20.2-0.1-0.31.3-1.91.91.9-1.9-1.8
Baseline Anxiety0.61.14.20.00.1-1.30.11.7-1.61.61.32.11.2-1.20.7-0.6-0.60.50.4-0.0-0.80.80.8-0.8-1.2
Tail length0.10.54.9-0.7-0.6-0.9-0.30.3-0.20.20.42.2-0.1-0.0-0.2-0.8-0.70.90.8-0.30.5-0.5-0.50.50.2
Length with tail0.21.03.8-1.7-1.8-1.31.80.10.0-0.10.62.00.40.40.1-0.6-0.60.80.8-0.60.9-0.9-0.90.91.4
Length without tail0.31.57.7-1.8-2.1-0.62.8-0.50.7-0.80.10.60.00.9-0.3-0.4-0.30.70.7-0.81.5-1.4-1.51.52.2
Times rat made contact with spout1.71.95.2-1.8-1.7-1.32.11.8-1.81.82.10.82.3-2.20.5-1.0-1.21.00.9-0.9-0.30.20.3-0.2-0.6
Lifetime Intake2.12.712.23.53.52.3-3.0-1.71.7-1.7-1.2-0.5-0.80.4-2.0-0.2-0.40.20.3-0.61.0-1.0-1.01.00.7
Liver weight, left2.95.013.0-3.5-3.6-1.82.91.4-1.21.22.51.42.4-1.7-1.5-2.7-2.72.72.7-2.71.7-1.8-1.81.80.5
Liver weight, right0.81.33.1-0.5-0.70.50.9-1.11.2-1.2-0.10.4-0.30.4-1.5-0.9-0.91.01.1-1.31.7-1.7-1.71.71.7
Locomotor activity1.82.85.7-1.4-1.5-2.41.12.1-2.02.10.6-1.20.6-0.22.31.21.5-1.4-1.51.6-2.22.22.2-2.2-1.1
Locomotor testing distance1.53.68.1-0.3-0.4-1.20.51.7-1.71.7-0.1-2.50.4-0.12.32.02.1-2.2-2.32.3-2.82.82.8-2.8-1.2
Locomotor testing rearing0.93.27.4-0.7-0.6-1.0-0.11.9-2.02.00.4-2.20.7-0.52.01.41.5-1.7-1.81.9-2.72.72.7-2.7-1.8
Locomotion in novel chamber0.60.82.5-1.1-1.0-1.01.60.4-0.40.40.0-1.60.30.71.40.70.9-0.7-0.70.9-0.70.70.7-0.7-0.3
Locomotion in novel chamber post-restriction0.41.14.0-2.0-1.9-1.91.11.5-1.51.51.0-0.30.4-0.31.4-0.00.2-0.0-0.10.4-0.80.80.8-0.8-0.2
Fecal boli incidents, locomotor time 10.51.34.70.3-0.10.20.3-1.21.2-1.2-1.6-2.1-2.02.20.11.01.3-1.0-0.91.00.1-0.1-0.10.11.9
Change in fecal boli incidents, locomotor task0.30.41.80.20.20.80.4-0.70.7-0.7-0.3-0.10.20.2-0.7-0.0-0.20.20.2-0.50.8-0.8-0.80.81.3
Time >=10cm from walls, locomotor time 11.31.73.61.21.2-0.0-1.6-0.50.4-0.4-1.4-1.7-1.91.61.11.61.8-1.6-1.61.6-1.01.11.0-1.1-0.9
Bouts of movement, locomotor time 11.31.77.50.50.20.70.4-1.81.7-1.7-2.2-1.4-2.22.7-0.11.21.4-1.1-1.01.30.2-0.2-0.20.21.0
Total resting periods, locomotor time 11.72.09.00.50.20.60.4-1.71.8-1.7-2.4-1.8-2.43.0-0.11.31.6-1.2-1.21.60.00.0-0.0-0.01.2
Rest time, locomotor task time 10.81.25.10.90.70.4-1.0-1.11.1-1.1-1.7-1.5-2.32.1-0.10.81.1-0.9-0.81.4-0.20.30.2-0.30.7
Distance moved, locomotor task time 10.51.65.6-0.8-0.6-0.80.91.7-1.81.81.70.51.9-2.41.80.2-0.1-0.2-0.3-0.3-1.11.11.1-1.0-1.2
Vertical activity count, locomotor time 10.21.55.4-0.4-0.2-0.60.31.7-1.81.81.71.02.1-2.31.5-0.1-0.30.0-0.1-0.4-1.01.01.0-1.0-1.7
Time >=10cm from walls, locomotor time 21.44.112.53.53.51.9-3.3-1.51.4-1.4-2.2-2.1-2.31.50.12.02.0-2.1-2.01.8-1.11.21.2-1.2-1.6
Bouts of movement, locomotor time 20.62.08.00.30.00.80.9-1.71.7-1.7-1.9-1.0-1.52.20.51.91.9-1.6-1.61.10.2-0.1-0.10.12.8
Total resting periods, locomotor time 20.41.45.9-0.2-0.30.41.0-1.11.1-1.1-1.5-0.9-1.11.90.81.71.7-1.5-1.51.2-0.20.20.2-0.22.4
Rest time, locomotor task time 20.40.72.4-0.9-1.0-0.80.40.00.00.0-0.8-1.2-0.91.50.60.60.9-0.7-0.71.4-0.70.70.6-0.70.6
Distance moved, locomotor task time 20.20.20.60.10.2-0.3-0.10.4-0.50.50.30.3-0.1-0.60.80.40.3-0.4-0.50.3-0.70.70.7-0.7-0.7
Vertical activity count, locomotor time 20.30.71.60.91.0-0.1-0.80.7-0.80.80.30.30.1-0.81.10.70.6-0.8-0.80.6-1.11.11.1-1.1-1.3
Light reinforcement 10.62.86.5-2.6-2.6-2.51.42.4-2.52.51.31.20.9-1.01.50.10.4-0.3-0.51.1-1.81.81.8-1.8-0.2
Light reinforcement 20.20.43.01.01.0-0.2-1.70.2-0.10.1-0.11.0-0.5-0.4-1.2-0.5-0.40.30.4-0.0-0.00.00.0-0.00.5
Bone: marrow area2.15.112.6-2.4-2.5-1.60.80.6-0.50.51.72.40.9-0.9-2.6-3.6-3.33.53.5-2.62.5-2.5-2.52.50.4
Bone: maximum diameter1.12.25.3-2.0-1.9-2.31.52.0-1.81.82.11.61.8-1.80.6-1.4-1.31.31.2-0.8-0.10.10.1-0.1-0.6
Bone: maximum force1.22.48.0-2.2-2.0-2.81.62.3-2.32.31.80.91.5-1.21.5-0.7-0.40.50.40.4-1.21.21.2-1.2-1.1
Bone: maximum moment1.32.47.3-2.2-2.1-2.71.52.3-2.32.31.90.91.6-1.41.3-0.9-0.70.70.60.1-1.01.01.0-1.0-1.3
Mean time between licks in bursts0.21.04.0-2.0-1.9-0.80.90.8-0.80.81.30.71.2-1.1-0.0-1.0-1.01.01.0-1.10.5-0.5-0.50.6-0.4
Mean num. licks in bursts0.51.27.4-2.1-2.30.32.7-0.70.8-0.80.2-0.70.50.5-0.1-0.1-0.20.30.3-0.91.1-1.1-1.11.10.8
Cd content in liver3.43.814.33.83.70.6-3.5-1.92.0-2.0-2.3-0.7-2.82.3-0.31.51.7-1.3-1.21.30.2-0.1-0.10.11.8
Co content in liver0.50.65.1-0.6-0.7-0.4-0.41.0-1.01.00.80.60.5-0.2-0.00.00.1-0.1-0.20.0-0.70.70.7-0.7-2.3
Cu content in liver2.22.66.71.11.00.2-0.1-0.40.3-0.2-1.1-1.8-1.11.61.62.52.6-2.5-2.52.0-1.71.71.7-1.7-1.5
Fe content in liver2.42.95.8-2.4-2.2-1.61.22.2-2.22.22.32.12.3-1.90.2-1.9-1.81.71.6-1.0-0.10.10.1-0.1-1.8
K content in liver0.40.42.51.61.60.8-1.0-0.30.4-0.4-0.20.3-0.0-0.1-0.10.50.3-0.4-0.4-0.1-0.00.00.0-0.0-0.4
Mg content in liver0.80.92.71.61.60.4-0.7-0.30.4-0.4-0.7-0.8-0.50.70.91.51.4-1.3-1.30.8-0.60.60.6-0.6-0.2
Mn content in liver0.30.31.0-0.8-1.0-1.00.60.2-0.20.20.40.40.20.2-0.3-0.7-0.50.70.7-0.60.6-0.6-0.60.60.2
Na content in liver2.93.39.1-3.0-2.9-1.92.82.0-1.91.92.42.12.4-2.30.7-1.4-1.51.41.3-1.40.2-0.2-0.20.2-0.5
Rb content in liver1.31.55.42.32.31.8-2.3-1.21.2-1.2-1.2-0.5-1.11.5-0.40.90.8-0.8-0.80.50.1-0.1-0.10.0-0.9
Se content in liver0.60.71.6-0.5-0.70.70.7-1.21.2-1.2-0.6-0.5-0.61.2-0.30.60.4-0.3-0.2-0.61.1-1.1-1.11.10.5
Sr content in liver0.70.61.9-1.3-1.4-0.91.00.3-0.30.30.41.10.3-1.0-0.8-0.8-0.80.80.8-0.60.5-0.5-0.50.51.1
Zn content in liver0.50.62.21.51.4-0.4-0.9-0.30.3-0.3-0.6-0.6-0.80.90.21.11.2-1.0-1.00.7-0.40.40.4-0.4-0.1
Bone: minimum diameter0.81.63.9-1.5-1.5-1.70.90.8-0.80.81.21.40.4-0.4-1.1-2.0-1.71.91.9-1.11.0-1.0-1.01.00.1
Time in familiar zone, hab. session 11.31.44.1-0.7-0.7-1.40.81.2-1.21.30.3-0.60.30.12.01.01.2-1.1-1.21.3-1.61.61.6-1.6-0.9
Time in novel zone, hab. session 11.31.44.01.61.52.0-1.1-1.71.5-1.5-1.6-1.4-1.51.1-0.41.11.0-1.1-1.00.60.1-0.1-0.10.00.7
Total zone transitions, hab. session 10.71.03.9-0.6-0.4-0.91.31.2-1.11.11.50.92.0-1.91.2-0.6-0.80.60.5-0.5-0.40.40.4-0.4-0.6
Total locomotion distance, hab. session 11.72.46.7-1.8-1.6-1.31.81.7-1.51.42.31.82.3-2.60.6-1.6-1.81.61.5-1.40.2-0.2-0.20.2-0.7
Locomotion velocity, hab. session 12.94.29.9-2.6-2.3-1.72.52.0-1.81.72.92.33.0-3.20.4-2.3-2.52.32.2-2.00.6-0.6-0.60.7-0.5
Time in familiar zone, hab. session 21.51.74.10.80.90.1-0.80.2-0.30.4-1.0-1.5-0.91.21.51.51.7-1.7-1.72.0-1.71.71.7-1.7-1.2
Time in novel zone, hab. session 20.40.41.30.20.20.6-0.1-0.70.8-0.8-0.20.2-0.0-0.1-1.0-0.4-0.50.50.5-0.80.9-0.9-0.90.91.2
Total zone transitions, hab. session 20.20.30.80.40.40.60.5-0.30.5-0.50.1-0.20.5-0.7-0.4-0.6-0.70.50.6-0.60.5-0.5-0.50.50.9
Total locomotion distance, hab. session 20.20.31.1-0.1-0.10.11.10.00.1-0.10.6-0.00.8-0.90.1-0.6-0.70.60.6-0.70.3-0.3-0.30.40.7
Locomotion velocity, hab. session 20.50.72.5-0.7-0.6-0.41.60.4-0.20.21.00.41.3-1.30.0-1.1-1.11.11.0-1.00.5-0.5-0.50.60.7
Novel to familiar place preference ratio3.14.010.63.02.92.9-3.3-2.82.8-2.8-2.3-0.8-2.51.8-2.20.30.2-0.2-0.1-0.01.3-1.3-1.31.30.8
Novelty place preference2.43.18.32.42.32.6-2.9-2.52.5-2.5-2.0-0.5-2.31.5-2.10.0-0.00.00.2-0.21.3-1.3-1.31.30.7
Time in novel zone, NPP test2.42.98.92.52.42.6-3.0-2.32.4-2.4-2.1-0.8-2.31.5-1.80.30.2-0.3-0.10.11.0-0.9-1.00.90.4
Total zone transitions, NPP test0.60.93.60.40.60.10.90.6-0.50.50.7-0.01.5-1.91.90.80.4-0.7-0.80.1-1.11.11.1-1.0-0.3
Total locomotion distance, NPP test0.30.42.2-0.2-0.0-0.31.30.5-0.30.30.70.31.2-1.51.40.30.0-0.2-0.3-0.0-0.60.60.6-0.50.3
Locomotion velocity, NPP test0.30.42.6-0.5-0.4-0.41.60.3-0.10.10.80.71.1-1.40.9-0.1-0.40.20.2-0.50.0-0.0-0.00.00.8
Intraocular pressure1.11.85.2-2.2-2.3-1.31.30.9-0.90.91.30.60.5-0.2-1.1-2.2-1.82.02.0-1.10.9-0.9-0.90.9-0.4
Delta distance traveled before/after self-admin2.62.99.51.71.42.3-0.2-2.42.4-2.3-2.7-0.5-2.32.3-1.21.31.3-1.2-1.01.10.5-0.5-0.50.53.1
Delta ambulatory time before/after self-admin2.23.88.72.52.22.8-1.1-2.92.9-2.9-2.8-0.3-2.42.3-1.91.00.9-0.9-0.70.51.1-1.1-1.11.12.7
Parametrial fat weight0.51.13.1-0.6-0.91.11.3-0.80.9-0.90.10.10.7-0.1-1.8-0.7-0.90.80.9-1.31.4-1.4-1.41.41.1
Pavlov. Cond. lever latency2.73.49.91.81.61.7-0.7-2.12.0-1.9-2.6-3.1-2.52.70.22.22.3-2.1-2.01.8-0.50.50.5-0.51.0
Pavlov. Cond. magazine entry latency3.03.87.1-2.7-2.6-2.12.62.0-1.81.82.42.12.7-1.8-0.6-2.5-2.32.32.2-1.70.7-0.8-0.80.80.1
Pavlov. Cond. change in total contacts2.32.57.5-1.8-1.7-1.31.41.1-1.01.01.82.71.8-1.6-0.5-2.1-2.12.12.0-1.61.0-1.1-1.01.10.4
Pavlov. Cond. index score4.15.110.4-2.6-2.4-2.41.82.7-2.52.53.13.23.2-3.0-0.2-2.8-2.72.62.5-1.90.4-0.4-0.40.5-0.7
Pavlov. Cond. latency score3.54.410.1-2.4-2.3-2.21.62.3-2.22.12.93.22.9-2.7-0.3-2.6-2.62.52.4-1.90.6-0.6-0.60.6-0.6
Pavlov. Cond. lever contacts2.83.48.2-2.0-1.8-1.31.51.8-1.81.72.62.72.8-2.9-0.0-2.1-2.32.12.0-2.00.6-0.7-0.60.7-0.5
Pavlov. Cond. magazine entry number4.55.710.53.23.13.0-2.7-2.72.5-2.5-3.1-3.0-3.22.30.33.02.8-2.8-2.61.8-0.60.60.6-0.60.3
Pavlov. Cond. intertrial magazine entries4.35.213.62.93.03.3-1.2-2.11.9-1.9-2.5-3.7-1.71.31.43.22.8-3.0-2.91.9-1.21.31.3-1.3-0.2
Pavlov. Cond. lever-magazine prob. diff.3.54.49.3-2.3-2.2-2.11.62.5-2.32.32.92.93.0-2.8-0.2-2.5-2.52.42.3-1.80.4-0.4-0.40.4-0.6
Pavlov. Cond. response bias5.77.114.6-3.2-3.0-2.92.33.3-3.13.13.63.63.8-3.4-0.1-3.2-3.13.02.8-2.00.3-0.3-0.30.4-0.9
Pavlov. Cond. lever latency0.60.81.5-1.0-1.10.30.5-0.20.1-0.10.40.80.2-0.2-1.1-1.2-1.21.21.2-1.21.1-1.1-1.11.10.1
Pavlov. Cond. magazine entry latency0.50.82.01.00.91.4-0.5-1.41.3-1.4-0.7-0.5-0.40.6-0.90.2-0.0-0.00.1-0.51.0-1.0-1.01.00.8
Pavlov. Cond. change in total contacts0.10.10.60.50.5-0.6-0.8-0.10.2-0.2-0.2-0.0-0.40.6-0.5-0.3-0.10.20.20.20.2-0.2-0.20.20.5
Pavlov. Cond. index score0.10.20.80.90.90.1-0.6-0.30.4-0.4-0.4-0.4-0.40.40.20.50.5-0.5-0.50.4-0.10.20.1-0.10.4
Pavlov. Cond. latency score0.30.41.61.31.30.4-1.0-0.70.7-0.7-0.7-0.4-0.80.70.00.60.6-0.5-0.50.50.0-0.0-0.00.00.6
Pavlov. Cond. lever contacts0.40.51.30.40.5-0.60.10.5-0.40.40.0-0.50.3-0.11.10.90.9-0.9-0.90.9-1.11.11.1-1.1-0.2
Pavlov. Cond. magazine entry number0.00.10.2-0.4-0.4-0.30.40.2-0.20.2-0.00.1-0.10.10.2-0.10.00.0-0.00.3-0.20.20.2-0.20.2
Pavlov. Cond. intertrial magazine entries0.30.62.2-1.1-1.3-0.81.50.4-0.50.5-0.2-1.0-0.20.80.50.60.8-0.7-0.70.9-0.80.80.8-0.80.3
Pavlov. Cond. lever-magazine prob. diff.0.20.30.91.01.00.0-0.9-0.40.4-0.4-0.6-0.4-0.60.50.10.50.6-0.5-0.50.6-0.20.20.2-0.20.4
Pavlov. Cond. response bias0.10.10.40.10.2-0.40.30.4-0.30.20.3-0.30.6-0.40.60.40.3-0.3-0.40.2-0.40.40.4-0.4-0.2
Time in closed arm before self-admin1.83.07.80.70.70.2-0.40.8-0.90.9-1.1-0.8-0.80.71.52.32.4-2.4-2.52.8-2.62.62.6-2.6-0.6
Time in closed arm after self-admin0.70.83.1-1.7-1.8-0.00.70.2-0.10.10.51.70.1-0.1-0.9-0.9-0.91.01.0-0.80.8-0.8-0.80.80.7
Time in open arm before self-admin2.83.47.8-2.0-2.1-1.91.20.4-0.30.31.72.31.2-0.2-1.1-2.8-2.52.82.7-2.12.0-2.0-2.02.00.3
Time in open arm after self-admin0.60.73.11.81.81.3-0.9-1.11.0-1.1-0.7-0.8-0.10.1-0.50.30.1-0.2-0.1-0.40.5-0.5-0.50.50.1
Bone: periosteal estimation1.53.68.1-2.8-2.8-2.81.42.0-1.91.92.32.21.5-1.6-0.4-2.6-2.22.42.3-1.30.6-0.7-0.60.7-0.6
Bone: periosteal perimeter0.71.44.7-1.7-1.7-2.21.01.5-1.41.31.41.40.7-0.9-0.1-1.4-1.21.31.2-0.60.1-0.1-0.10.1-0.3
Bone: post-yield work0.71.22.7-0.5-0.5-0.50.6-0.00.2-0.20.60.90.6-0.8-1.3-1.6-1.61.61.6-1.61.4-1.4-1.41.40.9
Progressive ratio test 1 active lever presses0.61.12.31.41.41.3-1.1-1.21.2-1.2-0.5-0.6-0.10.2-1.5-0.6-0.80.70.8-0.91.3-1.3-1.31.31.1
Progressive ratio test 1 breakpoint0.50.91.91.21.21.1-1.0-1.01.1-1.1-0.5-0.6-0.10.3-1.4-0.6-0.70.70.8-0.81.2-1.2-1.21.21.1
Progressive ratio test 1 inactive lever presses0.10.41.81.01.00.9-1.3-0.50.4-0.4-0.5-1.3-0.50.4-0.30.20.2-0.3-0.20.1-0.00.00.0-0.0-0.4
Progressive ratio test 2 active lever presses0.50.72.21.51.41.2-1.3-1.01.0-0.9-1.1-1.1-0.90.8-0.80.20.3-0.3-0.20.30.3-0.3-0.30.30.9
Progressive ratio test 2 breakpoint0.60.82.41.61.51.1-1.3-1.01.0-1.0-1.1-1.1-1.00.8-0.80.30.3-0.3-0.20.30.3-0.3-0.30.30.9
Progressive ratio test 2 inactive lever presses0.30.83.21.81.70.9-1.2-0.80.7-0.7-1.0-1.7-0.80.9-0.20.80.8-0.8-0.70.5-0.10.10.1-0.10.4
Incentive Sensitization - Responses0.30.82.21.21.21.5-1.0-1.11.1-1.1-1.3-0.3-1.30.8-0.50.80.7-0.8-0.70.50.2-0.1-0.10.11.1
Incentive Sensitization - Breakpoint0.41.02.21.41.31.5-1.1-1.21.1-1.1-1.4-0.4-1.40.9-0.40.90.9-0.9-0.80.70.0-0.0-0.00.01.1
Sum of active levers in priming session hrs 5-60.50.53.6-0.7-0.80.51.9-0.90.9-0.9-0.5-1.10.00.9-0.00.20.2-0.1-0.10.20.4-0.4-0.40.40.7
Progressive ratio0.10.31.10.20.3-1.0-0.50.8-0.80.80.70.00.4-0.50.3-0.4-0.30.30.20.2-0.50.50.5-0.5-0.8
Food seeking constrained by brief footshock0.60.71.70.70.70.1-0.4-0.20.1-0.1-0.7-1.2-0.60.90.91.21.3-1.2-1.21.2-0.90.90.9-0.90.2
Seeking ratio, punishment vs. effort0.20.41.40.20.11.20.2-0.80.8-0.8-0.9-0.2-0.50.50.00.90.7-0.8-0.70.20.2-0.2-0.20.21.0
Retroperitoneal fat weight0.10.41.8-0.2-0.3-0.4-0.30.00.1-0.10.10.4-0.20.4-1.3-0.9-0.70.90.9-0.50.7-0.7-0.70.70.6
Reaction time number correct0.00.10.9-0.1-0.00.70.10.2-0.20.20.10.30.4-1.00.20.2-0.0-0.3-0.3-0.0-0.40.40.4-0.40.2
Reaction time mean minus median0.00.21.5-0.2-0.3-0.2-0.1-0.30.3-0.3-0.8-0.2-1.11.0-0.10.10.3-0.2-0.10.7-0.10.20.1-0.21.2
Reaction time mean minus median AUC0.10.42.50.20.1-0.8-1.1-0.0-0.00.1-0.80.2-1.61.4-0.0-0.00.4-0.2-0.21.1-0.50.50.4-0.50.4
Reaction time num false alarms0.30.52.4-1.1-1.2-0.21.50.9-0.80.80.80.21.4-1.00.1-0.1-0.20.00.0-0.3-0.30.30.3-0.20.3
Reaction time num false alarms AUC0.20.52.0-1.0-1.1-0.11.30.7-0.70.70.80.21.4-1.1-0.2-0.3-0.50.30.3-0.60.0-0.0-0.00.00.2
Reaction time trials correct on left0.00.10.9-0.1-0.00.70.10.2-0.20.20.10.30.4-1.00.20.2-0.0-0.3-0.3-0.0-0.40.40.4-0.40.2
Reaction time trials on left0.00.10.9-0.1-0.10.70.10.2-0.20.20.10.30.4-0.90.20.2-0.0-0.2-0.2-0.1-0.30.30.3-0.30.2
Reaction time mean0.51.22.81.10.90.9-1.0-1.71.6-1.5-1.2-0.1-1.51.4-1.4-0.2-0.10.30.4-0.31.2-1.1-1.11.11.2
Reaction time mean AUC0.71.83.80.90.71.1-1.0-1.91.9-1.8-1.2-0.2-1.51.5-1.9-0.5-0.40.60.7-0.71.7-1.6-1.61.61.5
Median of all reaction times1.21.94.41.21.01.2-1.1-1.91.8-1.8-0.90.1-1.11.2-2.1-0.7-0.70.80.9-1.11.8-1.8-1.81.81.0
Reaction time omissions0.71.22.3-0.7-1.10.41.2-1.41.4-1.4-0.6-0.7-0.50.9-1.3-0.4-0.40.60.7-1.01.5-1.5-1.51.51.3
Reaction time false alarm rate0.10.20.6-0.4-0.5-0.00.80.1-0.10.10.4-0.10.8-0.3-0.5-0.3-0.30.30.3-0.60.4-0.4-0.40.40.2
Reaction time premature initiation rate1.82.87.31.31.31.7-0.1-1.11.0-0.9-1.8-2.3-1.31.11.62.72.5-2.6-2.62.0-1.41.41.4-1.40.5
Reaction time premature initiations0.92.87.51.11.11.8-0.1-0.90.7-0.7-1.6-2.0-1.00.71.82.72.4-2.6-2.62.0-1.61.61.6-1.60.6
Std. dev. reaction times0.10.41.80.30.20.2-0.7-0.70.6-0.6-1.1-0.3-1.31.30.00.50.7-0.5-0.50.8-0.20.20.2-0.20.8
Reaction time trials completed0.00.10.9-0.1-0.10.70.10.2-0.20.20.10.30.4-0.90.20.2-0.0-0.2-0.2-0.1-0.30.30.3-0.30.2
Reaction time trials AUC0.10.21.4-0.3-0.30.50.30.5-0.50.40.40.40.6-1.20.30.1-0.1-0.1-0.1-0.1-0.40.40.4-0.40.0
Run reversals in cocaine runway, females2.12.49.01.01.0-0.1-1.30.2-0.30.3-0.8-3.0-0.80.92.02.02.1-2.0-2.01.8-1.71.81.7-1.8-1.5
Run reversals in cocaine runway, males0.91.03.3-0.3-0.4-0.4-0.40.2-0.30.30.51.70.3-0.2-1.8-1.7-1.51.61.6-0.80.9-0.9-0.90.90.3
Latency to leave start box in cocaine runway2.12.97.6-2.8-2.7-1.12.31.6-1.41.32.21.72.2-2.0-0.2-1.7-1.91.81.7-1.80.9-0.9-0.90.9-0.1
Latency to leave start box in cocaine runway, F2.93.612.8-3.5-3.6-1.73.11.7-1.51.42.02.11.9-1.6-0.2-1.9-1.91.91.8-1.60.9-0.9-0.90.90.8
Latency to leave start box in cocaine runway, M0.40.41.40.00.20.60.10.1-0.10.10.9-0.01.1-1.2-0.3-0.4-0.70.50.5-1.20.5-0.5-0.50.5-1.1
Std. dev. time between licks in bursts1.32.55.6-0.7-0.5-2.1-0.51.9-2.12.10.90.70.3-0.82.40.60.9-0.8-1.01.6-2.32.32.3-2.3-1.9
Total sessions with >9 infusions0.91.15.72.22.31.3-2.4-0.90.9-0.9-0.60.1-0.50.3-1.0-0.2-0.30.20.3-0.30.6-0.6-0.60.60.0
Short access day 1 total inactive lever presses0.20.41.51.01.10.7-1.20.0-0.00.00.0-1.20.3-0.8-0.6-0.2-0.30.10.1-0.4-0.00.00.0-0.0-0.8
Short access day 10 total inactive lever presses0.00.33.2-0.5-0.4-0.5-0.20.5-0.60.60.7-1.20.2-0.60.3-0.2-0.20.10.1-0.4-0.20.20.2-0.2-1.8
Short access day 1 total infusions0.71.53.61.81.91.5-1.9-0.90.9-0.90.10.80.5-0.7-1.8-1.0-1.21.01.1-1.41.3-1.3-1.31.3-0.1
Short access day 10 total infusions2.23.69.32.62.62.3-2.8-1.81.9-1.9-0.50.8-0.2-0.2-3.0-1.4-1.71.51.6-1.92.2-2.2-2.22.20.9
Short access total infusions1.72.49.22.72.92.1-3.0-1.31.2-1.2-0.40.90.0-0.5-2.2-0.8-1.10.81.0-1.31.3-1.3-1.31.30.3
Short access day 1 locomotion0.50.82.71.61.70.8-1.4-0.70.7-0.7-1.0-0.8-0.81.00.30.80.9-0.8-0.80.9-0.50.50.5-0.5-0.7
Short access day 10 total locomotion0.21.03.01.31.11.2-1.3-1.21.2-1.2-1.0-0.0-1.10.8-1.7-0.2-0.20.20.3-0.31.0-0.9-0.90.91.1
Short access total locomotion1.11.76.02.42.41.6-2.3-1.61.6-1.5-1.4-0.5-1.31.2-1.30.30.3-0.2-0.10.00.7-0.7-0.70.70.7
One hour access (0.3 mA shock)1.01.25.12.22.21.6-1.8-1.11.0-1.0-1.2-1.4-0.70.7-0.60.90.7-0.8-0.70.4-0.10.10.1-0.10.5
Compulsive drug intake0.50.74.9-2.2-2.2-0.91.60.7-0.80.90.4-0.40.10.10.7-0.3-0.00.10.10.3-0.30.30.3-0.3-0.3
One hour access (shock baseline)0.41.06.42.52.51.1-2.1-0.60.7-0.7-0.5-0.2-0.20.2-1.10.1-0.0-0.1-0.0-0.20.2-0.2-0.20.20.1
Social response proportion1.51.97.00.2-0.10.81.0-1.91.8-1.8-2.0-2.6-1.52.60.21.41.6-1.3-1.21.10.2-0.2-0.20.10.9
Social responses1.62.18.0-0.2-0.3-0.41.0-0.10.0-0.0-1.1-2.8-0.71.21.71.92.1-2.0-2.02.0-1.61.61.6-1.6-0.4
Social time1.01.64.10.40.11.40.7-2.02.0-2.0-1.5-1.5-0.91.5-0.80.80.7-0.6-0.4-0.31.2-1.2-1.21.22.0
Soleus weight2.36.814.3-3.1-2.9-3.11.63.3-3.13.03.53.13.2-3.8-0.4-3.3-3.23.02.9-2.00.2-0.2-0.20.3-0.9
Bone: stiffness2.95.313.5-3.7-3.7-3.02.92.2-2.02.02.92.02.5-1.9-0.3-2.6-2.52.62.5-2.11.0-1.0-1.01.1-1.4
Tibialis anterior weight0.31.02.1-1.4-1.4-1.50.61.4-1.41.31.41.01.2-1.40.2-0.8-0.70.80.7-0.5-0.20.20.2-0.2-0.4
Time to tail flick, vehicle, before self-admin0.70.93.91.82.00.3-1.70.2-0.20.20.5-0.40.8-0.7-1.1-0.9-0.90.80.8-0.70.2-0.2-0.20.2-1.8
Time to tail flick, vehicle, after self-admin0.40.82.20.80.70.4-0.5-1.31.3-1.3-0.9-0.6-0.91.5-1.0-0.5-0.30.50.5-0.11.1-1.1-1.11.00.4
Time to tail flick, test, before self-admin1.01.22.40.91.01.0-0.40.1-0.30.3-0.5-1.0-0.1-0.31.21.51.3-1.5-1.51.2-1.51.51.5-1.5-0.9
Time to tail flick, test, after self-admin2.12.26.0-1.7-1.6-1.01.71.2-1.01.02.11.72.5-1.7-0.4-1.7-1.81.71.7-1.90.9-1.0-0.91.0-0.7
Delta time to tail flick, vehicle, before/after SA1.31.44.3-0.7-0.90.71.5-1.61.7-1.7-0.7-0.4-0.71.1-0.6-0.1-0.20.40.4-0.71.6-1.6-1.61.62.1
Delta time to tail flick, test, before/after SA2.53.15.8-1.9-2.0-1.61.30.9-0.70.72.12.21.8-1.2-1.1-2.3-2.32.42.3-2.41.7-1.8-1.71.8-0.1
Tibia length1.23.57.5-2.7-2.7-2.72.31.3-1.11.11.91.91.6-0.6-0.3-2.5-2.22.52.4-1.51.5-1.5-1.51.50.7
Ambulatory time before self-admin1.03.06.7-1.3-0.9-1.8-0.42.4-2.62.61.2-0.60.6-1.32.20.30.5-0.6-0.71.3-2.42.32.3-2.3-2.5
Ambulatory time after self-admin2.13.46.71.41.41.5-1.1-1.10.8-0.8-2.3-2.3-2.21.71.12.52.6-2.6-2.52.5-1.61.61.6-1.60.9
Bone: tissue strength0.60.61.50.80.70.6-0.6-1.11.2-1.2-0.6-0.3-0.50.6-1.0-0.2-0.20.30.4-0.51.0-1.0-1.01.01.1
Total heroin consumption0.80.94.8-1.3-1.2-0.22.20.7-0.60.51.2-0.42.1-1.30.5-0.3-0.60.40.4-1.00.3-0.3-0.30.3-0.7
Bone: trabecular number0.71.44.3-1.4-1.4-2.11.51.7-1.71.81.11.01.0-0.51.2-0.3-0.00.20.10.5-1.01.01.0-1.0-0.8
Bone: trabecular spacing0.20.40.8-0.5-0.50.60.1-0.30.3-0.30.10.20.1-0.6-0.9-0.5-0.70.60.6-0.90.8-0.8-0.80.80.9
Bone: trabecular thickness1.62.26.0-1.4-1.3-2.51.02.3-2.32.31.80.71.5-0.91.5-0.3-0.10.20.00.4-1.31.31.3-1.3-2.2
Bone: trabecular tissue density0.30.52.3-0.4-0.40.3-0.20.3-0.40.40.2-0.10.3-0.10.90.90.8-0.9-0.90.5-0.80.80.8-0.8-1.5
Water consumed over 24 hours1.02.05.3-1.7-1.7-1.42.31.9-1.91.91.80.52.1-1.90.1-1.3-1.31.21.1-0.9-0.20.20.2-0.2-0.3
Number of responses in last shaping day0.30.41.20.40.40.3-0.7-0.40.5-0.50.30.30.3-0.5-0.8-0.5-0.70.70.7-1.10.9-0.9-0.90.90.3