Hub : Genes

Arhgef19

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain alternative polyA XM_008764270.4 0.07 0.05 2.1e-03 -0 0.02 0.02 0 5.8e-01 4.1e-03 3.0e-03 1.1e-01
2 Brain alternative polyA XM_008764270.4 0.07 0.05 2.6e-03 -0 0.02 0.02 0 6.3e-01 6.2e-03 3.3e-03 1.7e-01
3 Liver mRNA stability Arhgef19 0.03 0.02 9.8e-03 0.01 0 0 -0 6.1e-02 3.0e-01 3.2e-01 3.9e-01
4 Brain alternative polyA NM_001108692.1 0.06 0.05 8.1e-03 -0 0.01 0.01 -0 6.4e-01 6.7e-02 1.5e-02 8.8e-01
5 OFC alternative TSS XM_008764270.4 0.21 0.13 4.5e-03 0.07 0.04 0.04 0.08 9.3e-03 3.1e-02 5.1e-02 5.7e-03
6 OFC alternative TSS NM_001108692.1 0.26 0.15 2.3e-03 0.09 0.05 0.04 0.1 3.3e-03 2.0e-02 3.4e-02 2.7e-03
7 OFC alternative TSS XM_008764270.4 0.27 0.15 1.9e-03 0.09 0.06 0.04 0.1 3.7e-03 2.0e-02 5.2e-02 3.0e-03
8 Liver gene expression Arhgef19 0.55 0.14 0.0e+00 0.4 0.44 0.47 0.43 5.7e-48 5.7e-53 1.5e-57 1.3e-51
9 NAcc gene expression Arhgef19 0.04 0.03 4.7e-04 0.01 0.01 0.01 0.01 7.3e-03 4.2e-03 2.8e-03 4.2e-03
10 Brain gene expression Arhgef19 0.04 0.03 8.2e-03 0.02 0.02 0.01 0.02 4.4e-03 8.1e-03 2.6e-02 9.7e-03
11 Adipose gene expression Arhgef19 0.03 0.02 5.8e-03 0.01 0 0 -0 5.1e-02 3.0e-01 3.3e-01 8.4e-01
12 NAcc isoform ratio NM_001108692.1 0.05 0.03 8.8e-05 0.03 0.03 0.02 0.03 3.0e-05 1.9e-05 4.1e-04 1.8e-05
13 NAcc alternative polyA NM_001108692.1 0.04 0.02 1.1e-04 0.03 0.03 0.03 0.03 1.0e-04 1.6e-05 6.1e-05 1.3e-05
14 NAcc alternative polyA NM_001108692.1 0.04 0.02 2.6e-04 0.02 0.03 0.02 0.03 2.4e-04 4.1e-05 2.3e-04 9.8e-05
15 NAcc alternative polyA XM_008764270.4 0.04 0.02 1.5e-04 0.03 0.03 0.02 0.03 1.0e-04 2.9e-05 2.5e-04 4.3e-05
16 NAcc alternative polyA XM_008764270.4 0.04 0.02 1.2e-04 0.02 0.03 0.02 0.03 1.3e-04 2.3e-05 1.2e-04 3.0e-05
17 PL gene expression Arhgef19 0.04 0.02 1.1e-03 0 0.02 0.01 0.01 1.9e-01 1.7e-03 3.8e-02 2.2e-02
18 Liver alternative polyA XM_008764270.4 0.07 0.05 3.3e-05 0.01 0.02 0.01 0.01 1.0e-02 2.5e-03 6.1e-02 4.2e-02
19 Liver alternative polyA NM_001108692.1 0.07 0.04 2.5e-05 0.01 0.02 0.01 0.01 8.8e-03 2.4e-03 3.0e-02 4.3e-02
20 Liver alternative polyA NM_001108692.1 0.07 0.04 2.6e-05 0.01 0.02 0.01 0.01 8.6e-03 3.0e-03 5.5e-02 4.4e-02
21 Liver alternative polyA XM_008764270.4 0.07 0.05 4.2e-05 0.01 0.02 0.01 0.01 1.4e-02 3.2e-03 5.8e-02 6.7e-02
22 Liver isoform ratio NM_001108692.1 0.07 0.07 3.0e-04 0 0.01 0.02 0 1.0e-01 4.4e-02 6.2e-03 3.1e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density1.52.58.41.81.72.9-1.52.5-2.52.5-2.0-1.3-1.71.0-1.41.2-0.50.70.50.2-1.01.01.0-1.01.6
Area under the delay curve1.11.38.31.91.91.0-2.90.3-0.20.2-1.20.4-1.50.5-1.40.3-0.70.80.8-1.10.9-0.9-0.90.9-0.8
BMI with tail0.51.63.8-0.8-0.6-0.80.4-1.71.7-1.71.51.81.7-2.00.6-1.50.20.10.2-0.21.3-1.3-1.31.3-1.6
BMI without tail0.51.65.5-1.4-1.2-0.61.4-1.61.5-1.41.91.42.3-2.21.3-0.80.8-0.5-0.40.80.5-0.4-0.50.4-1.1
Body weight0.20.93.00.81.10.7-1.2-0.60.7-0.70.2-0.20.5-1.2-0.6-0.8-0.40.80.8-0.61.4-1.4-1.41.4-1.7
Weight adjusted by age0.60.96.20.81.00.3-0.8-0.80.9-0.80.80.20.7-1.30.2-1.3-0.60.80.90.10.9-0.9-0.90.9-2.5
Bone surface1.42.69.32.01.93.0-1.82.5-2.52.5-1.9-1.5-1.51.0-1.41.2-0.70.90.70.3-1.00.90.9-0.90.9
Bone volume2.03.510.92.12.03.3-2.02.8-2.82.8-2.5-1.8-2.21.7-2.01.2-1.21.31.1-0.3-0.70.70.7-0.71.3
Breakpoint value in progressive ratio session0.20.22.40.20.1-0.3-0.20.0-0.00.00.21.5-0.1-0.20.30.50.4-0.5-0.50.2-0.30.30.3-0.30.9
Number of licking bursts1.01.63.9-1.3-1.61.01.41.8-2.02.0-1.0-1.0-0.81.8-0.20.5-0.40.20.10.5-1.41.41.4-1.41.2
Context. condit. distance diff. score1.41.75.60.1-0.21.01.51.8-1.91.8-1.4-1.4-1.01.9-0.70.7-0.50.30.20.2-1.41.41.4-1.42.4
Locomotion velocity, session 11.21.36.60.70.50.20.11.4-1.51.4-1.5-1.5-1.92.6-0.80.4-1.00.60.5-0.6-0.80.80.8-0.81.2
Locomotion distance, session 10.50.64.2-0.0-0.2-0.1-0.80.6-0.60.5-1.0-0.1-1.72.1-0.41.0-0.3-0.1-0.1-0.5-0.60.60.6-0.50.3
Locomotion velocity, session 20.20.32.2-0.2-0.3-1.5-0.1-0.30.1-0.2-0.20.2-0.81.20.10.40.0-0.4-0.4-0.5-0.20.20.2-0.20.8
Locomotion distance, session 20.81.13.00.10.2-1.0-1.6-0.91.0-1.1-0.40.3-0.91.0-0.9-0.7-0.90.80.8-1.71.4-1.4-1.41.4-0.6
Locomotion velocity, session 30.30.30.9-0.7-0.8-0.30.80.0-0.10.10.10.90.20.30.40.30.4-0.5-0.50.4-0.70.70.7-0.70.9
Locomotion distance, session 30.80.94.8-1.7-1.90.32.20.7-0.70.6-0.7-0.9-0.51.3-0.30.0-0.60.40.4-0.1-0.60.50.6-0.51.1
Stereotopy head waving bouts, day 31.11.26.81.11.3-1.4-2.0-1.51.4-1.40.82.60.1-1.10.3-0.30.5-0.5-0.4-0.40.8-0.8-0.80.8-0.7
Stereotopy head waving duration, day 31.11.38.10.30.5-1.6-1.2-1.51.3-1.31.32.80.7-1.31.20.21.3-1.3-1.30.40.1-0.1-0.10.1-0.6
Locomotion velocity, session 71.21.36.4-1.4-1.60.52.50.8-0.80.80.0-0.90.80.20.50.40.3-0.3-0.41.3-1.51.41.4-1.51.6
Locomotion distance, session 70.81.04.5-0.4-0.61.11.11.4-1.31.3-0.9-2.1-0.61.3-0.40.5-0.90.80.70.3-0.80.80.8-0.80.7
Stereotopy head waving bouts, day 70.30.31.4-0.1-0.10.7-0.30.6-0.60.6-0.11.2-0.20.20.20.90.5-0.4-0.50.6-0.80.80.8-0.80.2
Stereotopy head waving duration, day 70.60.71.50.20.10.9-0.11.2-1.21.2-0.51.1-0.60.60.01.00.4-0.4-0.50.6-1.11.11.1-1.11.1
Locomotion velocity, session 80.70.93.0-0.4-0.5-0.60.9-0.1-0.0-0.0-0.9-1.2-0.91.7-1.1-0.8-1.41.11.1-1.50.7-0.7-0.70.71.0
Locomotion distance, session 81.21.76.21.10.91.4-0.31.7-1.71.6-2.0-1.4-1.72.5-1.50.5-1.21.00.9-0.8-0.60.50.6-0.51.6
Degree of sensitization distance0.30.31.20.80.9-0.2-0.8-0.60.5-0.50.6-0.30.5-0.80.3-0.2-0.10.20.20.10.4-0.4-0.40.4-1.1
Degree of sensitization stereotypy0.50.51.7-0.2-0.31.30.00.9-0.90.9-0.20.50.00.20.21.10.5-0.4-0.50.9-1.01.01.0-1.00.1
Conditioned locomotion1.41.63.7-1.3-1.4-1.7-0.5-1.51.5-1.51.21.70.7-0.71.41.21.8-1.9-1.90.8-0.40.50.5-0.5-0.5
Cocaine response after cond. corrected4.55.411.7-2.3-2.0-2.60.9-3.43.4-3.32.61.52.5-2.81.0-2.7-0.10.40.6-0.72.6-2.5-2.52.5-3.3
Cocaine response after cond. not corrected4.04.710.6-2.7-2.5-2.51.1-3.23.1-3.02.91.82.6-2.91.7-1.80.6-0.4-0.20.11.7-1.6-1.71.6-3.3
Cocaine response before conditioning1.82.25.10.2-0.11.2-0.32.0-2.02.0-0.80.0-1.11.30.42.20.8-1.0-1.11.4-2.22.22.2-2.21.2
Saline control response0.91.23.11.01.10.8-1.40.3-0.40.40.31.00.2-1.00.81.71.7-1.5-1.61.5-1.21.21.2-1.2-0.6
Bone: connectivity density1.01.56.01.61.62.4-1.51.9-1.91.9-0.9-0.5-0.70.1-0.41.20.10.1-0.01.0-1.21.21.2-1.20.2
Bone: cortical apparent density1.21.73.9-1.5-1.6-1.30.7-0.60.6-0.61.50.71.1-0.62.01.01.8-1.9-1.91.6-1.21.31.3-1.3-0.8
Bone: cortical area2.03.18.62.11.92.9-1.72.7-2.62.6-1.8-0.7-1.41.4-0.82.30.00.0-0.20.8-1.71.71.7-1.71.3
Bone: cortical porosity0.91.03.2-0.5-0.4-0.6-1.8-1.31.3-1.30.81.7-0.2-0.80.81.01.1-1.1-1.10.30.2-0.1-0.10.1-1.6
Bone: cortical porosity1.11.24.3-0.3-0.2-0.9-1.9-1.61.7-1.70.71.2-0.4-0.50.2-0.20.2-0.2-0.2-0.81.2-1.2-1.21.2-2.1
Bone: cortical thickness2.33.812.00.70.52.1-1.22.0-1.92.0-0.51.2-0.40.51.03.52.0-1.9-2.12.3-2.92.92.9-2.91.2
Bone: cortical thickness1.72.05.81.71.52.0-1.41.9-1.81.8-1.4-0.5-1.21.0-0.52.40.2-0.2-0.30.7-1.41.41.4-1.41.7
Bone: cortical tissue density1.31.74.1-1.7-1.8-1.50.9-0.80.7-0.71.60.71.2-0.72.00.81.7-1.8-1.81.6-1.11.11.1-1.1-0.9
Condit. Reinf. active minus inactive responses0.20.20.9-0.5-0.6-0.2-0.30.4-0.30.3-0.40.8-0.90.7-0.20.2-0.30.10.1-0.3-0.10.10.1-0.10.6
Condit. Reinf. active-inactive response ratio0.10.11.10.00.0-0.0-0.70.1-0.0-0.0-0.21.1-0.80.0-0.3-0.4-0.10.10.1-0.40.2-0.2-0.20.20.0
Condit. Reinf. active responses0.30.41.3-0.7-0.9-0.30.20.7-0.70.7-0.40.6-0.81.00.20.7-0.1-0.2-0.20.2-0.70.70.7-0.71.1
Condit. Reinf. inactive responses0.20.20.4-0.3-0.4-0.50.60.1-0.20.20.2-0.10.30.50.60.70.1-0.2-0.20.4-0.60.60.6-0.60.7
Incentive salience index mean0.40.52.2-0.1-0.30.2-0.61.0-0.90.8-0.80.5-1.51.4-0.30.7-0.30.10.0-0.2-0.50.50.6-0.50.7
Condit. Reinf. lever presses0.70.93.1-0.0-0.20.7-0.11.6-1.51.4-1.0-0.5-1.41.7-0.21.1-0.2-0.0-0.10.1-1.11.11.1-1.10.8
Condit. Reinf. active minus inactive responses0.10.10.6-0.5-0.50.30.8-0.20.2-0.20.20.10.5-0.6-0.1-0.60.10.00.10.10.1-0.1-0.20.10.4
Condit. Reinf. active-inactive response ratio0.60.72.1-1.4-1.4-0.81.2-1.00.9-0.91.11.01.1-1.10.7-0.70.4-0.4-0.30.30.3-0.3-0.30.3-0.3
Condit. Reinf. active responses0.40.51.40.80.71.2-0.30.9-0.80.8-1.1-1.0-0.90.6-1.00.3-0.40.40.4-0.3-0.20.20.2-0.21.1
Condit. Reinf. inactive responses1.72.26.42.52.41.8-2.31.8-1.71.6-1.9-1.1-2.11.5-1.21.6-0.40.30.2-0.3-0.70.70.7-0.71.0
Condit. Reinf. lever presses1.11.53.51.11.01.9-0.71.7-1.61.5-1.8-1.7-1.71.6-1.60.2-1.31.21.1-0.6-0.20.20.2-0.20.6
Condit. Reinf. lever reinforcers received0.40.62.00.70.61.4-0.00.8-0.70.7-1.1-1.4-0.80.5-1.2-0.0-0.70.70.7-0.50.1-0.1-0.10.10.8
Conditioned reinforcement - actives0.20.44.4-0.3-0.3-0.0-0.10.1-0.10.10.32.1-0.1-0.70.60.50.6-0.6-0.60.6-0.50.50.5-0.50.2
Conditioned reinforcement - inactives0.40.63.3-0.9-0.7-0.90.4-1.11.0-1.00.91.80.7-0.90.5-0.70.3-0.2-0.1-0.10.6-0.6-0.60.6-0.7
Conditioned locomotion0.20.23.50.20.30.0-0.4-0.10.1-0.00.11.9-0.3-0.50.2-0.30.1-0.1-0.10.1-0.00.00.0-0.0-0.3
Patch foraging indifference point 0 sec2.54.612.1-0.4-0.40.2-0.60.1-0.10.11.62.71.3-1.12.52.93.5-3.4-3.43.1-2.62.72.6-2.6-0.6
Patch foraging indifference point AUC2.84.111.81.00.63.00.13.4-3.43.4-2.2-2.5-1.72.5-1.01.8-0.80.70.50.8-2.02.02.0-2.01.3
Delay disc. indifference point, 0s delay2.52.87.71.81.61.1-2.41.2-1.21.1-2.6-1.0-2.82.3-2.40.5-1.91.71.6-2.00.7-0.8-0.70.81.0
Delay disc. indifference point, 16s delay0.91.03.91.61.60.8-2.00.2-0.10.0-1.00.1-1.20.4-1.30.0-0.70.80.8-1.21.0-1.0-1.01.1-1.1
Delay disc. indifference point, 2s delay0.70.86.91.51.50.9-2.60.10.0-0.0-0.70.2-0.9-0.0-0.90.6-0.40.60.5-0.60.6-0.6-0.60.6-0.9
Delay disc. indifference point, 24s delay0.20.21.60.20.2-0.0-1.3-0.40.4-0.40.20.9-0.1-0.50.10.50.6-0.5-0.60.10.1-0.1-0.10.1-0.2
Delay disc. indifference point, 4s delay0.70.75.01.11.20.2-2.2-0.60.6-0.6-0.10.7-0.5-0.5-0.6-0.0-0.20.40.4-0.71.0-0.9-1.01.0-1.1
Delay disc. indifference point, 8s delay1.41.76.51.51.50.7-2.6-0.0-0.00.0-1.30.4-1.50.7-1.7-0.5-1.31.41.4-1.71.4-1.4-1.41.4-0.9
Indifference point function ln k2.13.79.8-0.9-0.6-2.9-0.8-3.13.1-3.11.71.41.0-1.20.4-2.10.1-0.10.1-1.52.4-2.4-2.42.4-2.2
Indifference point function log k2.13.79.8-0.9-0.6-2.9-0.8-3.13.1-3.11.71.41.0-1.20.4-2.10.1-0.10.1-1.52.4-2.4-2.42.4-2.2
Patch foraging total patch changes 0 sec2.24.211.0-0.4-0.40.2-0.60.1-0.10.11.42.61.2-0.92.42.83.3-3.2-3.32.9-2.52.52.5-2.5-0.7
Patch foraging total patch changes 12 sec4.05.212.91.51.22.8-0.63.2-3.13.1-1.3-0.2-1.11.30.53.61.5-1.5-1.72.2-3.23.23.2-3.21.8
Patch foraging total patch changes 18 sec6.710.227.32.11.82.7-1.03.4-3.43.5-0.60.7-0.20.81.95.23.0-3.1-3.34.1-4.84.84.8-4.81.5
Patch foraging total patch changes 24 sec3.35.712.22.82.63.5-2.03.5-3.53.5-1.7-1.1-1.21.5-0.23.20.8-0.7-0.92.1-2.92.92.9-2.90.7
Patch foraging total patch changes 6 sec3.04.610.71.00.82.3-1.02.5-2.42.4-0.30.5-0.20.41.23.22.0-1.9-2.12.9-3.33.33.3-3.2-0.0
Patch foraging time to switch 0 sec0.40.92.7-1.0-0.9-1.11.0-1.31.3-1.31.40.71.2-1.71.0-0.30.8-0.7-0.70.60.2-0.2-0.20.1-0.0
Patch foraging water rate 0 sec0.81.63.80.80.61.5-0.71.9-1.92.0-0.90.1-0.81.30.21.80.3-0.4-0.61.0-1.71.71.7-1.70.5
Patch foraging water rate 12 sec0.40.83.91.92.01.1-1.60.8-0.90.9-0.71.1-0.60.5-0.21.0-0.00.10.0-0.0-0.30.30.3-0.3-0.3
Patch foraging water rate 18 sec0.81.23.81.81.90.5-1.50.2-0.20.3-0.8-0.1-0.90.5-1.2-1.0-1.31.31.3-1.41.1-1.1-1.11.1-0.9
Patch foraging water rate 24 sec0.20.20.7-0.5-0.5-0.60.3-0.70.6-0.60.60.80.5-0.10.5-0.1-0.10.10.1-0.10.4-0.3-0.30.3-0.9
Patch foraging water rate 6 sec0.50.83.31.11.11.0-1.80.6-0.60.7-0.11.4-0.30.10.41.40.6-0.5-0.60.7-0.80.80.8-0.8-1.0
Seeking ratio, delayed vs. immediate footshock1.01.22.80.30.31.20.30.7-0.70.6-1.1-1.2-0.70.9-1.6-1.1-1.61.71.7-1.51.1-1.1-1.11.1-0.2
Distance traveled before self-admin2.02.66.51.41.21.90.52.4-2.52.6-1.20.4-0.51.20.11.90.3-0.4-0.51.1-2.12.12.1-2.12.2
Distance traveled after self-admin1.62.04.7-0.3-0.3-0.10.70.4-0.50.61.01.01.2-0.61.91.61.9-1.9-2.02.2-2.02.02.0-2.00.1
Extensor digitorum longus weight0.10.30.90.40.40.9-0.10.8-0.90.9-0.6-0.4-0.50.5-0.5-0.1-0.20.30.2-0.0-0.30.30.3-0.30.4
Bone: elastic displacement2.22.66.1-1.1-1.3-0.20.30.0-0.20.21.10.90.8-0.52.12.22.3-2.3-2.42.5-2.22.22.2-2.2-0.8
Bone: elastic work1.82.37.00.2-0.00.9-0.61.1-1.11.20.10.8-0.10.11.32.61.8-1.8-1.92.2-2.32.32.3-2.30.1
Bone: endosteal estimation2.35.012.32.42.51.6-0.70.6-0.50.5-1.8-2.5-1.01.0-2.9-2.6-3.33.53.5-2.62.4-2.5-2.52.5-0.4
Bone: endosteal perimeter1.22.56.01.11.20.5-0.60.00.1-0.2-1.1-1.7-0.60.8-2.0-2.1-2.32.42.5-2.22.0-2.0-2.02.0-0.6
Epididymis fat weight0.41.53.60.60.80.2-0.2-0.20.4-0.4-0.80.1-0.40.0-1.7-1.7-1.51.71.7-1.91.7-1.7-1.71.70.6
Delta time in closed arm before/after self-admin6.05.611.12.52.61.1-1.40.2-0.10.1-2.1-3.2-1.41.1-3.0-1.9-3.13.33.3-3.32.9-2.9-2.92.9-1.1
Delta time in open arm before/after self-admin1.11.14.9-1.8-1.8-2.21.1-1.41.3-1.41.10.90.60.00.7-1.00.1-0.4-0.2-0.40.6-0.5-0.50.5-0.2
Diff in mean of infusions in LGA sessions0.00.00.20.20.2-0.00.1-0.20.2-0.10.3-0.20.3-0.40.2-0.00.2-0.1-0.10.4-0.10.10.1-0.10.1
Delay discount exponential model param0.91.06.9-1.6-1.6-0.92.60.0-0.00.10.8-0.51.1-0.01.2-0.20.5-0.7-0.61.0-0.90.90.9-0.91.0
Extinction: sum of active levers before priming1.41.513.41.71.8-1.2-3.7-0.80.7-0.70.12.2-1.20.30.00.30.3-0.5-0.5-0.40.3-0.3-0.30.3-1.6
Active lever presses in extinction session 61.01.02.40.10.1-1.5-0.7-1.31.3-1.30.30.1-0.1-0.1-0.5-1.6-0.80.70.8-1.11.4-1.4-1.41.4-0.9
Bone: final force1.62.67.12.52.32.7-1.92.2-2.22.2-1.6-0.9-1.50.9-0.91.8-0.10.30.10.6-1.31.31.3-1.31.3
Bone: final moment1.62.66.72.52.42.6-1.82.2-2.22.2-1.8-0.9-1.51.2-1.11.6-0.40.40.30.4-1.21.21.2-1.21.5
Food consumed during 24 hour testing period0.70.92.90.20.21.3-0.40.8-0.80.8-1.0-1.2-0.70.6-1.7-1.2-1.31.41.4-1.00.7-0.7-0.70.70.0
Glucose0.10.20.80.20.30.0-0.2-0.0-0.00.00.30.80.4-0.90.40.20.5-0.4-0.40.6-0.30.30.3-0.3-0.1
Heart weight1.32.16.22.52.52.4-1.82.1-2.22.2-1.10.6-1.20.2-0.51.00.10.10.00.8-1.21.21.2-1.10.0
Delay discount hyperbolic model param1.01.17.9-1.6-1.7-0.92.80.0-0.10.10.9-0.51.2-0.11.2-0.30.5-0.6-0.61.0-0.90.90.9-0.90.9
Intermittent access intake day 1-15 change0.61.23.3-1.5-1.4-0.61.0-0.90.9-0.81.51.31.8-1.51.4-0.11.2-1.1-1.11.3-0.50.60.5-0.6-0.4
Intermittent access intake escalation0.61.23.5-1.8-1.6-0.81.3-1.11.0-1.01.51.01.9-1.41.3-0.31.0-0.9-0.81.1-0.30.30.3-0.4-0.3
Intermittent access intake escalation 20.40.52.1-1.4-1.3-0.51.0-0.60.7-0.70.80.11.0-0.70.6-0.50.4-0.4-0.30.5-0.10.10.1-0.1-0.3
Intermitt. access day 1 inactive lever presses0.10.21.5-1.1-1.2-0.20.90.2-0.30.3-0.30.5-0.20.6-0.1-0.1-0.1-0.1-0.1-0.2-0.20.20.2-0.20.7
Intermitt. access day 15 inactive lever presses0.20.30.90.40.30.3-0.30.5-0.30.3-0.70.5-0.80.7-0.8-0.4-0.90.90.9-0.70.4-0.4-0.40.40.2
Intermitt. access escalation Index0.40.62.20.20.10.5-0.60.6-0.70.7-0.10.6-0.70.30.51.50.8-0.8-0.90.9-1.01.01.0-1.0-0.0
Intermittent access day 1 total infusions0.50.83.2-1.7-1.8-1.30.9-0.80.8-0.80.30.2-0.40.0-0.1-1.2-0.50.30.4-0.80.8-0.8-0.80.8-0.6
Intermittent access day 15 total infusions1.32.07.2-2.7-2.6-1.61.7-1.71.7-1.71.41.31.2-1.10.6-1.9-0.10.10.3-0.31.0-1.0-1.01.0-1.2
Intermittent access terminal intake (last 3 days)1.62.110.8-3.3-3.2-1.62.6-1.41.4-1.41.30.31.2-0.90.9-1.60.1-0.2-0.00.10.5-0.5-0.50.5-0.7
Intermittent access total infusions2.12.59.4-3.1-3.0-2.22.4-1.81.8-1.81.30.80.9-0.80.6-2.0-0.30.20.3-0.61.2-1.2-1.21.2-1.2
Intermittent access day 1 locomotion0.60.73.2-1.8-1.8-1.21.4-0.90.9-0.90.70.30.5-0.40.4-1.1-0.0-0.00.0-0.20.5-0.5-0.50.5-0.6
Intermittent access day 15 total locomotion0.50.92.2-1.4-1.2-0.80.9-1.01.1-1.11.0-0.21.1-1.20.4-1.30.10.00.1-0.10.9-0.9-0.90.9-1.5
Intermittent access total locomotion2.02.55.5-2.3-2.2-1.81.5-1.91.9-1.92.31.02.1-2.11.8-1.01.2-1.1-1.01.00.3-0.2-0.20.2-1.7
Intermittent access standard deviation0.30.74.5-1.9-2.0-0.62.1-0.10.0-0.0-0.10.7-0.20.5-0.1-0.7-0.40.20.3-0.50.0-0.0-0.00.01.3
Left kidney weight0.94.313.73.73.73.3-2.82.8-2.72.7-2.5-1.1-2.41.4-2.10.8-1.21.41.3-0.7-0.20.20.2-0.20.3
Right kidney weight0.62.98.12.82.82.6-2.42.1-1.91.9-2.1-1.2-2.11.2-2.00.3-1.41.51.4-1.00.3-0.3-0.30.3-0.2
Cocaine induced anxiety0.91.32.61.11.11.2-0.71.0-1.11.2-0.11.30.2-0.40.51.31.0-0.9-1.01.6-1.61.61.6-1.60.8
Post-drug Anxiety2.22.36.51.31.32.5-1.12.3-2.42.4-1.2-0.2-0.80.4-0.31.40.2-0.1-0.31.3-1.91.91.9-1.91.8
Baseline Anxiety0.91.14.2-0.0-0.11.3-0.11.7-1.61.6-1.3-2.1-1.21.2-0.70.7-0.60.50.4-0.0-0.80.80.8-0.81.2
Tail length0.10.54.90.60.60.90.20.3-0.20.2-0.4-2.20.10.0-0.7-0.2-0.70.90.8-0.30.5-0.5-0.50.5-0.2
Length with tail0.21.13.81.71.81.3-1.80.10.0-0.1-0.6-2.0-0.4-0.4-1.00.1-0.60.80.8-0.60.9-0.9-0.90.9-1.3
Length without tail0.51.57.11.82.00.6-2.7-0.60.7-0.8-0.1-0.6-0.0-0.9-0.8-0.3-0.30.70.7-0.81.5-1.4-1.51.5-2.2
Times rat made contact with spout1.82.05.21.81.71.3-2.31.8-1.91.8-2.1-0.8-2.32.2-1.60.5-1.21.00.9-0.9-0.30.20.3-0.20.6
Lifetime Intake2.22.612.1-3.5-3.5-2.32.9-1.71.6-1.71.20.50.8-0.40.6-2.0-0.40.20.3-0.61.0-1.0-1.01.0-0.7
Liver weight, left3.15.113.13.53.61.8-2.91.3-1.21.2-2.5-1.4-2.41.7-3.1-1.5-2.72.72.7-2.71.7-1.8-1.81.8-0.5
Liver weight, right0.81.33.10.60.7-0.5-0.9-1.11.2-1.20.1-0.40.3-0.4-0.8-1.5-0.91.01.1-1.31.7-1.7-1.71.7-1.8
Locomotor activity1.82.85.71.41.52.4-1.12.1-2.02.1-0.61.2-0.60.20.32.31.5-1.4-1.51.6-2.22.22.2-2.21.1
Locomotor testing distance2.03.58.10.40.41.2-0.51.7-1.71.70.12.5-0.40.11.32.32.1-2.2-2.32.3-2.82.82.8-2.81.2
Locomotor testing rearing1.63.17.40.70.61.00.12.0-2.02.0-0.42.2-0.70.51.02.01.5-1.7-1.81.9-2.72.72.7-2.71.9
Locomotion in novel chamber0.60.72.51.11.01.0-1.50.4-0.40.4-0.01.6-0.3-0.70.31.40.9-0.7-0.70.9-0.70.70.7-0.70.4
Locomotion in novel chamber post-restriction0.71.13.81.91.91.9-1.11.5-1.51.5-1.00.3-0.40.3-0.51.40.2-0.0-0.10.4-0.80.80.8-0.80.2
Fecal boli incidents, locomotor time 10.91.44.7-0.20.1-0.2-0.2-1.21.2-1.21.62.12.0-2.21.20.11.3-1.0-0.91.00.1-0.1-0.10.1-1.9
Change in fecal boli incidents, locomotor task0.40.41.8-0.2-0.2-0.8-0.4-0.70.7-0.70.30.1-0.2-0.2-0.0-0.7-0.20.20.2-0.50.8-0.8-0.80.8-1.3
Time >=10cm from walls, locomotor time 11.61.73.6-1.2-1.20.01.6-0.50.5-0.41.41.71.9-1.61.71.11.8-1.6-1.61.6-1.01.11.0-1.10.9
Bouts of movement, locomotor time 11.51.87.5-0.5-0.2-0.7-0.2-1.71.8-1.72.21.42.2-2.71.7-0.11.4-1.1-1.01.30.2-0.2-0.20.2-1.0
Total resting periods, locomotor time 11.92.19.0-0.5-0.2-0.6-0.2-1.71.8-1.72.41.82.4-3.01.9-0.11.6-1.2-1.21.60.00.0-0.0-0.0-1.2
Rest time, locomotor task time 11.01.35.1-0.9-0.8-0.41.1-1.11.1-1.11.71.52.3-2.11.4-0.11.1-0.9-0.81.4-0.20.30.2-0.3-0.7
Distance moved, locomotor task time 11.11.65.60.80.60.8-1.01.7-1.91.8-1.7-0.5-1.92.4-0.71.8-0.1-0.2-0.3-0.3-1.11.11.1-1.01.2
Vertical activity count, locomotor time 10.61.55.40.40.20.6-0.41.7-1.81.8-1.7-1.0-2.12.3-0.61.5-0.30.0-0.1-0.4-1.01.01.0-1.01.7
Time >=10cm from walls, locomotor time 22.84.212.5-3.5-3.5-1.93.4-1.41.4-1.42.22.12.3-1.52.30.12.0-2.1-2.01.8-1.11.21.2-1.21.6
Bouts of movement, locomotor time 21.21.97.8-0.2-0.0-0.8-0.9-1.71.7-1.71.91.01.5-2.21.60.51.9-1.6-1.61.10.2-0.1-0.10.1-2.8
Total resting periods, locomotor time 20.81.45.60.20.3-0.4-1.0-1.11.1-1.11.50.91.1-1.91.50.81.7-1.5-1.51.2-0.20.20.2-0.2-2.4
Rest time, locomotor task time 20.50.72.40.91.00.8-0.30.00.00.00.81.20.9-1.50.90.60.9-0.7-0.71.4-0.70.70.6-0.7-0.5
Distance moved, locomotor task time 20.20.20.6-0.1-0.20.30.10.4-0.50.5-0.3-0.30.10.60.10.80.3-0.4-0.50.3-0.70.70.7-0.70.7
Vertical activity count, locomotor time 20.50.71.6-0.9-1.00.10.80.7-0.80.8-0.3-0.3-0.10.80.41.10.6-0.8-0.80.6-1.11.11.1-1.11.3
Light reinforcement 11.12.86.52.52.62.5-1.42.4-2.52.5-1.3-1.2-0.91.0-0.41.50.4-0.3-0.51.1-1.81.81.8-1.80.2
Light reinforcement 20.30.43.1-1.1-1.00.21.80.2-0.10.10.1-1.00.50.4-0.0-1.2-0.40.30.4-0.0-0.00.00.0-0.0-0.6
Bone: marrow area2.24.912.22.42.51.6-0.70.5-0.50.5-1.7-2.4-0.90.9-2.9-2.6-3.33.53.5-2.62.5-2.5-2.52.5-0.4
Bone: maximum diameter1.22.25.32.01.92.3-1.62.0-1.81.8-2.1-1.6-1.81.8-1.80.6-1.31.31.2-0.8-0.10.10.1-0.10.7
Bone: maximum force1.42.58.02.22.02.8-1.62.3-2.32.3-1.8-0.9-1.51.2-1.11.5-0.40.50.40.4-1.21.21.2-1.21.2
Bone: maximum moment1.42.47.32.22.12.7-1.52.3-2.32.3-1.9-0.9-1.61.4-1.31.3-0.70.70.60.1-1.01.01.0-1.01.3
Mean time between licks in bursts0.41.13.92.02.00.8-0.90.8-0.80.8-1.3-0.7-1.21.1-1.2-0.0-1.01.01.0-1.10.5-0.5-0.50.60.4
Mean num. licks in bursts0.81.27.02.22.3-0.3-2.6-0.70.8-0.8-0.20.7-0.5-0.5-0.6-0.1-0.20.30.3-0.91.1-1.1-1.11.1-0.8
Cd content in liver3.43.814.2-3.8-3.7-0.63.4-1.92.0-2.02.30.72.8-2.31.8-0.31.7-1.3-1.21.30.2-0.1-0.10.1-1.8
Co content in liver0.50.65.00.60.70.40.41.0-1.01.0-0.8-0.6-0.50.2-0.6-0.00.1-0.1-0.20.0-0.70.70.7-0.72.2
Cu content in liver2.02.46.7-1.1-1.0-0.20.2-0.40.3-0.21.11.81.1-1.61.51.62.6-2.5-2.52.0-1.71.71.7-1.71.5
Fe content in liver2.42.95.52.42.21.6-1.22.2-2.22.2-2.3-2.1-2.31.9-1.90.2-1.81.71.6-1.0-0.10.10.1-0.11.8
K content in liver0.40.42.5-1.6-1.6-0.80.9-0.30.4-0.40.2-0.30.00.10.2-0.10.3-0.4-0.4-0.1-0.00.00.0-0.00.4
Mg content in liver0.80.82.6-1.6-1.6-0.40.6-0.30.4-0.40.70.80.5-0.70.90.91.4-1.3-1.30.8-0.60.60.6-0.60.2
Mn content in liver0.30.31.00.81.01.0-0.50.2-0.20.2-0.4-0.4-0.2-0.2-0.7-0.3-0.50.70.7-0.60.6-0.6-0.60.6-0.2
Na content in liver3.23.49.13.02.91.9-2.82.0-1.91.9-2.4-2.1-2.42.3-2.10.7-1.51.41.3-1.40.2-0.2-0.20.20.5
Rb content in liver1.31.55.5-2.3-2.3-1.82.2-1.21.2-1.21.20.51.1-1.51.0-0.40.8-0.8-0.80.50.1-0.1-0.10.00.8
Se content in liver0.50.61.60.50.7-0.7-0.6-1.21.2-1.20.60.50.6-1.20.1-0.30.4-0.3-0.2-0.61.1-1.1-1.11.1-0.5
Sr content in liver0.70.61.91.31.40.9-1.00.3-0.30.3-0.4-1.1-0.31.0-0.6-0.8-0.80.80.8-0.60.5-0.5-0.50.5-1.1
Zn content in liver0.50.52.1-1.4-1.40.40.8-0.30.3-0.30.60.60.8-0.90.40.21.2-1.0-1.00.7-0.40.40.4-0.40.1
Bone: minimum diameter0.81.53.61.51.51.7-0.90.8-0.80.8-1.2-1.4-0.40.4-1.7-1.1-1.71.91.9-1.11.0-1.0-1.01.0-0.1
Time in familiar zone, hab. session 11.41.44.10.70.71.4-0.71.2-1.21.3-0.30.6-0.3-0.10.52.01.2-1.1-1.21.3-1.61.61.6-1.60.9
Time in novel zone, hab. session 11.51.54.0-1.6-1.5-2.01.1-1.71.5-1.51.61.41.5-1.11.5-0.41.0-1.1-1.00.60.1-0.1-0.10.0-0.7
Total zone transitions, hab. session 10.71.03.90.60.40.9-1.41.2-1.11.1-1.5-0.9-2.01.9-0.91.2-0.80.60.5-0.5-0.40.40.4-0.40.6
Total locomotion distance, hab. session 11.72.46.71.81.61.3-1.91.6-1.51.4-2.3-1.8-2.32.6-1.90.6-1.81.61.5-1.40.2-0.2-0.20.20.7
Locomotion velocity, hab. session 13.04.29.92.62.31.7-2.72.0-1.81.7-2.9-2.3-3.03.2-2.50.4-2.52.32.2-2.00.6-0.6-0.60.70.5
Time in familiar zone, hab. session 21.71.84.1-0.9-0.9-0.10.80.2-0.30.41.01.50.9-1.21.71.51.7-1.7-1.72.0-1.71.71.7-1.71.2
Time in novel zone, hab. session 20.40.41.4-0.2-0.2-0.60.1-0.70.8-0.80.2-0.20.00.1-0.4-1.0-0.50.50.5-0.80.9-0.9-0.90.9-1.2
Total zone transitions, hab. session 20.20.30.8-0.4-0.4-0.6-0.6-0.30.5-0.5-0.10.2-0.50.7-0.2-0.4-0.70.50.6-0.60.5-0.5-0.50.5-0.9
Total locomotion distance, hab. session 20.20.31.30.10.1-0.1-1.10.00.1-0.1-0.60.0-0.80.9-0.60.1-0.70.60.6-0.70.3-0.3-0.30.4-0.7
Locomotion velocity, hab. session 20.50.72.70.70.60.4-1.70.4-0.20.2-1.0-0.4-1.31.3-1.10.0-1.11.11.0-1.00.5-0.5-0.50.6-0.7
Novel to familiar place preference ratio3.74.110.7-3.0-2.9-2.93.3-2.82.8-2.82.30.82.5-1.81.4-2.20.2-0.2-0.1-0.01.3-1.3-1.31.3-0.9
Novelty place preference2.93.18.5-2.4-2.3-2.62.9-2.42.5-2.52.00.52.3-1.51.1-2.1-0.00.00.2-0.21.3-1.3-1.31.3-0.7
Time in novel zone, NPP test2.83.09.1-2.5-2.4-2.63.0-2.32.4-2.42.10.82.3-1.51.3-1.80.2-0.3-0.10.11.0-0.9-1.00.9-0.5
Total zone transitions, NPP test0.60.83.6-0.3-0.6-0.1-1.00.6-0.50.5-0.70.0-1.51.90.11.90.4-0.7-0.80.1-1.11.11.1-1.00.4
Total locomotion distance, NPP test0.30.52.20.20.00.3-1.40.5-0.30.3-0.7-0.3-1.21.5-0.21.40.0-0.2-0.3-0.0-0.60.60.6-0.5-0.3
Locomotion velocity, NPP test0.30.52.80.50.40.4-1.70.2-0.10.1-0.8-0.7-1.11.4-0.60.9-0.40.20.2-0.50.0-0.0-0.00.0-0.7
Intraocular pressure1.21.75.22.22.31.3-1.20.9-0.90.9-1.3-0.6-0.50.2-1.8-1.1-1.82.02.0-1.10.9-0.9-0.90.90.4
Delta distance traveled before/after self-admin2.83.09.5-1.7-1.5-2.30.3-2.42.4-2.32.70.52.3-2.31.9-1.21.3-1.2-1.01.10.5-0.5-0.50.5-3.1
Delta ambulatory time before/after self-admin3.13.98.6-2.4-2.2-2.81.2-2.92.9-2.92.80.32.4-2.31.7-1.90.9-0.9-0.70.51.1-1.1-1.11.1-2.7
Parametrial fat weight0.51.13.10.70.9-1.1-1.3-0.90.9-0.9-0.1-0.1-0.70.1-0.7-1.8-0.90.80.9-1.31.4-1.4-1.41.4-1.1
Pavlov. Cond. lever latency2.73.59.9-1.7-1.6-1.70.7-2.02.0-1.92.63.12.5-2.72.40.22.3-2.1-2.01.8-0.50.50.5-0.5-0.9
Pavlov. Cond. magazine entry latency3.03.87.12.72.62.1-2.62.0-1.81.8-2.4-2.1-2.71.8-2.5-0.6-2.32.32.2-1.70.7-0.8-0.80.8-0.1
Pavlov. Cond. change in total contacts2.32.47.51.81.71.3-1.41.1-1.01.0-1.8-2.7-1.81.6-2.0-0.5-2.12.12.0-1.61.0-1.1-1.01.1-0.4
Pavlov. Cond. index score4.15.210.42.62.42.4-1.92.7-2.52.5-3.1-3.2-3.23.0-2.9-0.2-2.72.62.5-1.90.4-0.4-0.40.50.6
Pavlov. Cond. latency score3.64.510.12.42.32.2-1.72.3-2.22.1-2.9-3.2-2.92.7-2.8-0.3-2.62.52.4-1.90.6-0.6-0.60.60.5
Pavlov. Cond. lever contacts2.93.58.22.01.81.3-1.61.8-1.81.7-2.6-2.7-2.82.9-2.4-0.0-2.32.12.0-2.00.6-0.7-0.60.70.5
Pavlov. Cond. magazine entry number4.65.810.5-3.2-3.1-3.02.8-2.62.5-2.53.13.03.2-2.33.10.32.8-2.8-2.61.8-0.60.60.6-0.6-0.3
Pavlov. Cond. intertrial magazine entries4.35.113.6-2.9-3.0-3.31.2-2.11.9-1.92.53.71.7-1.33.11.42.8-3.0-2.91.9-1.21.31.3-1.30.2
Pavlov. Cond. lever-magazine prob. diff.3.64.49.32.32.22.1-1.72.5-2.32.3-2.9-2.9-3.02.8-2.7-0.2-2.52.42.3-1.80.4-0.4-0.40.40.6
Pavlov. Cond. response bias5.87.214.63.23.02.9-2.43.2-3.13.1-3.6-3.6-3.83.4-3.3-0.1-3.13.02.8-2.00.3-0.3-0.30.40.8
Pavlov. Cond. lever latency0.60.71.51.01.1-0.3-0.4-0.20.1-0.1-0.4-0.8-0.20.2-0.8-1.1-1.21.21.2-1.21.1-1.1-1.11.1-0.1
Pavlov. Cond. magazine entry latency0.60.82.0-1.0-0.9-1.40.5-1.41.3-1.40.70.50.4-0.60.2-0.9-0.0-0.00.1-0.51.0-1.0-1.01.0-0.8
Pavlov. Cond. change in total contacts0.10.10.6-0.5-0.50.60.8-0.10.2-0.20.20.00.4-0.6-0.2-0.5-0.10.20.20.20.2-0.2-0.20.2-0.5
Pavlov. Cond. index score0.10.20.8-0.9-0.9-0.10.6-0.30.4-0.40.40.40.4-0.40.30.20.5-0.5-0.50.4-0.10.20.1-0.1-0.4
Pavlov. Cond. latency score0.30.41.6-1.3-1.3-0.41.0-0.70.7-0.70.70.40.8-0.70.60.00.6-0.5-0.50.50.0-0.0-0.00.0-0.6
Pavlov. Cond. lever contacts0.40.51.3-0.4-0.50.6-0.10.5-0.40.4-0.00.5-0.30.10.41.10.9-0.9-0.90.9-1.11.11.1-1.10.2
Pavlov. Cond. magazine entry number0.00.10.20.40.40.3-0.40.2-0.20.20.0-0.10.1-0.10.20.20.00.0-0.00.3-0.20.20.2-0.2-0.2
Pavlov. Cond. intertrial magazine entries0.40.62.11.11.30.8-1.50.4-0.50.50.21.00.2-0.80.40.50.8-0.7-0.70.9-0.80.80.8-0.8-0.2
Pavlov. Cond. lever-magazine prob. diff.0.20.30.9-1.0-1.0-0.00.9-0.40.4-0.40.60.40.6-0.50.40.10.6-0.5-0.50.6-0.20.20.2-0.2-0.4
Pavlov. Cond. response bias0.10.10.4-0.1-0.20.4-0.30.4-0.30.2-0.30.3-0.60.4-0.10.60.3-0.3-0.40.2-0.40.40.4-0.40.2
Time in closed arm before self-admin2.43.07.8-0.7-0.7-0.20.50.8-0.90.91.10.80.8-0.72.11.52.4-2.4-2.52.8-2.62.62.6-2.60.7
Time in closed arm after self-admin0.70.83.11.71.80.0-0.60.2-0.10.1-0.5-1.7-0.10.1-0.8-0.9-0.91.01.0-0.80.8-0.8-0.80.8-0.7
Time in open arm before self-admin3.03.37.72.02.11.9-1.10.4-0.30.3-1.7-2.3-1.20.2-2.5-1.1-2.52.82.7-2.12.0-2.0-2.02.0-0.3
Time in open arm after self-admin0.60.73.1-1.7-1.7-1.30.9-1.11.0-1.10.70.80.1-0.10.3-0.50.1-0.2-0.1-0.40.5-0.5-0.50.5-0.1
Bone: periosteal estimation1.73.57.92.82.82.8-1.42.0-1.91.9-2.3-2.2-1.51.6-2.5-0.4-2.22.42.3-1.30.6-0.7-0.60.70.6
Bone: periosteal perimeter0.81.44.71.71.72.2-1.01.5-1.41.3-1.4-1.4-0.70.9-1.5-0.1-1.21.31.2-0.60.1-0.1-0.10.10.3
Bone: post-yield work0.81.22.70.50.60.5-0.6-0.00.2-0.2-0.6-0.9-0.60.8-1.2-1.3-1.61.61.6-1.61.4-1.4-1.41.4-0.9
Progressive ratio test 1 active lever presses0.91.12.3-1.4-1.4-1.31.0-1.21.2-1.20.50.60.1-0.2-0.1-1.5-0.80.70.8-0.91.3-1.3-1.31.3-1.1
Progressive ratio test 1 breakpoint0.80.91.9-1.2-1.2-1.10.9-1.01.1-1.10.50.60.1-0.3-0.1-1.4-0.70.70.8-0.81.2-1.2-1.21.2-1.1
Progressive ratio test 1 inactive lever presses0.30.41.8-1.0-1.0-0.91.3-0.50.4-0.40.51.30.5-0.40.6-0.30.2-0.3-0.20.1-0.00.00.0-0.00.4
Progressive ratio test 2 active lever presses0.60.72.2-1.5-1.4-1.21.3-1.01.0-0.91.11.10.9-0.80.8-0.80.3-0.3-0.20.30.3-0.3-0.30.3-0.9
Progressive ratio test 2 breakpoint0.70.82.4-1.6-1.5-1.11.4-1.01.0-1.01.11.11.0-0.80.8-0.80.3-0.3-0.20.30.3-0.3-0.30.3-1.0
Progressive ratio test 2 inactive lever presses0.50.83.0-1.7-1.7-0.91.2-0.80.7-0.71.01.70.8-0.91.0-0.20.8-0.8-0.70.5-0.10.10.1-0.1-0.4
Incentive Sensitization - Responses0.60.82.2-1.3-1.2-1.51.0-1.11.1-1.11.30.31.3-0.81.1-0.50.7-0.8-0.70.50.2-0.1-0.10.1-1.1
Incentive Sensitization - Breakpoint0.81.02.2-1.4-1.3-1.51.1-1.21.1-1.11.40.41.4-0.91.2-0.40.9-0.9-0.80.70.0-0.0-0.00.0-1.1
Sum of active levers in priming session hrs 5-60.50.53.40.70.8-0.5-1.9-0.90.9-0.90.51.1-0.0-0.90.1-0.00.2-0.1-0.10.20.4-0.4-0.40.4-0.6
Progressive ratio0.20.31.1-0.2-0.31.00.50.8-0.80.8-0.7-0.0-0.40.5-0.40.3-0.30.30.20.2-0.50.50.5-0.50.8
Food seeking constrained by brief footshock0.60.71.7-0.7-0.7-0.10.3-0.20.1-0.10.71.20.6-0.91.00.91.3-1.2-1.21.2-0.90.90.9-0.9-0.1
Seeking ratio, punishment vs. effort0.30.41.4-0.2-0.1-1.2-0.2-0.80.8-0.80.90.20.5-0.50.70.00.7-0.8-0.70.20.2-0.2-0.20.2-1.0
Retroperitoneal fat weight0.10.41.80.20.30.40.40.00.1-0.1-0.1-0.40.2-0.4-0.6-1.3-0.70.90.9-0.50.7-0.7-0.70.7-0.6
Reaction time number correct0.10.10.90.10.0-0.7-0.10.2-0.20.2-0.1-0.3-0.41.00.40.2-0.0-0.3-0.3-0.0-0.40.40.4-0.4-0.2
Reaction time mean minus median0.10.31.50.20.30.20.2-0.30.3-0.30.80.21.1-1.00.6-0.10.3-0.2-0.10.7-0.10.20.1-0.2-1.2
Reaction time mean minus median AUC0.20.52.5-0.2-0.10.81.2-0.0-0.00.10.8-0.21.6-1.40.6-0.00.4-0.2-0.21.1-0.50.50.4-0.5-0.4
Reaction time num false alarms0.40.52.51.11.20.2-1.60.8-0.80.8-0.8-0.2-1.41.0-0.50.1-0.20.00.0-0.3-0.30.30.3-0.2-0.3
Reaction time num false alarms AUC0.30.52.01.11.10.1-1.40.7-0.70.7-0.8-0.2-1.41.1-0.6-0.2-0.50.30.3-0.60.0-0.0-0.00.0-0.2
Reaction time trials correct on left0.10.10.90.10.0-0.7-0.10.2-0.20.2-0.1-0.3-0.41.00.40.2-0.0-0.3-0.3-0.0-0.40.40.4-0.4-0.2
Reaction time trials on left0.10.10.90.10.1-0.7-0.10.2-0.20.2-0.1-0.3-0.40.90.40.2-0.0-0.2-0.2-0.1-0.30.30.3-0.3-0.2
Reaction time mean0.81.22.7-1.0-0.9-0.91.1-1.71.6-1.51.20.11.5-1.40.5-1.4-0.10.30.4-0.31.2-1.1-1.11.1-1.2
Reaction time mean AUC1.11.83.8-0.9-0.7-1.11.0-1.91.9-1.81.20.21.5-1.50.2-1.9-0.40.60.7-0.71.7-1.6-1.61.6-1.5
Median of all reaction times1.31.94.4-1.2-1.0-1.21.1-1.91.8-1.80.9-0.11.1-1.2-0.1-2.1-0.70.80.9-1.11.8-1.8-1.81.8-1.1
Reaction time omissions0.81.22.30.81.1-0.4-1.1-1.41.4-1.40.60.70.5-0.9-0.2-1.3-0.40.60.7-1.01.5-1.5-1.51.5-1.3
Reaction time false alarm rate0.10.20.60.40.50.0-0.80.1-0.10.1-0.40.1-0.80.3-0.6-0.5-0.30.30.3-0.60.4-0.4-0.40.4-0.2
Reaction time premature initiation rate2.02.86.8-1.3-1.3-1.70.1-1.11.0-0.91.82.31.3-1.12.41.62.5-2.6-2.62.0-1.41.41.4-1.4-0.5
Reaction time premature initiations1.52.77.0-1.1-1.2-1.80.0-0.80.7-0.71.62.01.0-0.72.51.82.4-2.6-2.62.0-1.61.61.6-1.6-0.5
Std. dev. reaction times0.20.51.8-0.3-0.2-0.20.8-0.70.6-0.61.10.31.3-1.31.00.00.7-0.5-0.50.8-0.20.20.2-0.2-0.8
Reaction time trials completed0.10.10.90.10.1-0.7-0.10.2-0.20.2-0.1-0.3-0.40.90.40.2-0.0-0.2-0.2-0.1-0.30.30.3-0.3-0.2
Reaction time trials AUC0.10.21.40.30.3-0.5-0.30.5-0.50.4-0.4-0.4-0.61.20.20.3-0.1-0.1-0.1-0.1-0.40.40.4-0.40.0
Run reversals in cocaine runway, females2.32.39.0-1.0-1.00.11.30.3-0.30.30.83.00.8-0.91.52.02.1-2.0-2.01.8-1.71.81.7-1.81.5
Run reversals in cocaine runway, males0.90.93.30.30.40.40.40.2-0.30.3-0.5-1.7-0.30.2-1.2-1.8-1.51.61.6-0.80.9-0.9-0.90.9-0.3
Latency to leave start box in cocaine runway2.63.07.62.82.71.1-2.41.5-1.41.3-2.2-1.7-2.22.0-2.1-0.2-1.91.81.7-1.80.9-0.9-0.90.90.1
Latency to leave start box in cocaine runway, F3.23.712.73.53.61.7-3.11.7-1.51.4-2.0-2.1-1.91.6-2.1-0.2-1.91.91.8-1.60.9-0.9-0.90.9-0.8
Latency to leave start box in cocaine runway, M0.40.41.4-0.0-0.2-0.6-0.20.1-0.10.1-0.90.0-1.11.2-0.7-0.3-0.70.50.5-1.20.5-0.5-0.50.51.1
Std. dev. time between licks in bursts1.82.55.60.60.52.10.51.9-2.12.1-0.9-0.7-0.30.80.22.40.9-0.8-1.01.6-2.32.32.3-2.32.0
Total sessions with >9 infusions0.91.15.4-2.2-2.3-1.32.3-0.90.9-0.90.6-0.10.5-0.30.3-1.0-0.30.20.3-0.30.6-0.6-0.60.6-0.1
Short access day 1 total inactive lever presses0.30.31.5-1.0-1.1-0.71.20.0-0.00.0-0.01.2-0.30.80.0-0.6-0.30.10.1-0.4-0.00.00.0-0.00.8
Short access day 10 total inactive lever presses0.10.33.10.40.40.50.20.5-0.60.6-0.71.2-0.20.6-0.40.3-0.20.10.1-0.4-0.20.20.2-0.21.8
Short access day 1 total infusions1.11.43.5-1.8-1.9-1.51.8-0.90.9-0.9-0.1-0.8-0.50.7-0.7-1.8-1.21.01.1-1.41.3-1.3-1.31.30.0
Short access day 10 total infusions2.83.59.3-2.6-2.6-2.32.7-1.81.8-1.90.5-0.80.20.2-0.6-3.0-1.71.51.6-1.92.2-2.2-2.22.2-0.9
Short access total infusions1.82.38.5-2.7-2.8-2.12.9-1.31.2-1.20.4-0.9-0.00.5-0.3-2.2-1.10.81.0-1.31.3-1.3-1.31.3-0.4
Short access day 1 locomotion0.70.92.7-1.6-1.7-0.81.5-0.70.7-0.71.00.80.8-1.01.20.30.9-0.8-0.80.9-0.50.50.5-0.50.7
Short access day 10 total locomotion0.51.03.0-1.3-1.1-1.21.3-1.21.2-1.21.00.01.1-0.80.3-1.7-0.20.20.3-0.31.0-0.9-0.90.9-1.2
Short access total locomotion1.41.75.9-2.4-2.4-1.62.3-1.61.6-1.51.40.51.3-1.20.9-1.30.3-0.2-0.10.00.7-0.7-0.70.7-0.7
One hour access (0.3 mA shock)1.11.24.9-2.2-2.2-1.61.7-1.11.0-1.01.21.40.7-0.71.2-0.60.7-0.8-0.70.4-0.10.10.1-0.1-0.5
Compulsive drug intake0.60.74.92.22.20.9-1.60.7-0.80.9-0.40.4-0.1-0.1-0.30.7-0.00.10.10.3-0.30.30.3-0.30.3
One hour access (shock baseline)0.61.06.3-2.5-2.5-1.12.0-0.60.6-0.70.50.20.2-0.20.4-1.1-0.0-0.1-0.0-0.20.2-0.2-0.20.2-0.1
Social response proportion1.61.97.0-0.10.1-0.8-0.8-1.91.8-1.82.02.61.5-2.61.50.21.6-1.3-1.21.10.2-0.2-0.20.1-0.9
Social responses1.62.08.00.20.30.4-0.9-0.00.1-0.01.12.80.7-1.21.61.72.1-2.0-2.02.0-1.61.61.6-1.60.4
Social time1.21.64.1-0.3-0.1-1.4-0.7-2.02.0-2.01.51.50.9-1.50.8-0.80.7-0.6-0.4-0.31.2-1.2-1.21.2-2.0
Soleus weight2.36.714.33.12.93.1-1.73.3-3.13.0-3.5-3.1-3.23.8-3.1-0.4-3.23.02.9-2.00.2-0.2-0.20.30.9
Bone: stiffness3.35.413.63.73.73.0-2.82.1-2.02.0-2.9-2.0-2.51.9-3.1-0.3-2.52.62.5-2.11.0-1.0-1.01.11.3
Tibialis anterior weight0.31.02.11.41.41.5-0.71.4-1.41.3-1.4-1.0-1.21.4-1.10.2-0.70.80.7-0.5-0.20.20.2-0.20.4
Time to tail flick, vehicle, before self-admin0.80.93.9-1.8-2.0-0.31.70.2-0.20.2-0.50.4-0.80.7-0.6-1.1-0.90.80.8-0.70.2-0.2-0.20.21.8
Time to tail flick, vehicle, after self-admin0.60.82.2-0.8-0.7-0.40.5-1.31.3-1.30.90.60.9-1.50.1-1.0-0.30.50.5-0.11.1-1.1-1.11.0-0.4
Time to tail flick, test, before self-admin1.11.22.4-0.9-1.0-1.00.40.1-0.30.30.51.00.10.31.41.21.3-1.5-1.51.2-1.51.51.5-1.50.9
Time to tail flick, test, after self-admin2.22.36.01.71.61.0-1.81.2-1.01.0-2.1-1.7-2.51.7-2.1-0.4-1.81.71.7-1.90.9-1.0-0.91.00.7
Delta time to tail flick, vehicle, before/after SA1.51.44.30.80.9-0.7-1.4-1.61.7-1.70.70.40.7-1.1-0.0-0.6-0.20.40.4-0.71.6-1.6-1.61.6-2.1
Delta time to tail flick, test, before/after SA3.13.26.91.92.01.6-1.40.9-0.80.7-2.1-2.2-1.81.2-2.6-1.1-2.32.42.3-2.41.7-1.8-1.71.80.1
Tibia length1.33.47.52.72.62.7-2.41.3-1.11.1-1.9-1.9-1.60.6-2.4-0.3-2.22.52.4-1.51.5-1.5-1.51.5-0.7
Ambulatory time before self-admin2.03.06.71.20.91.80.42.5-2.62.6-1.20.6-0.61.30.22.20.5-0.6-0.71.3-2.42.32.3-2.32.6
Ambulatory time after self-admin2.93.48.3-1.5-1.4-1.51.2-1.00.9-0.82.32.32.2-1.72.91.12.6-2.6-2.52.5-1.61.61.6-1.6-0.8
Bone: tissue strength0.60.61.5-0.8-0.7-0.60.5-1.11.2-1.20.60.30.5-0.6-0.1-1.0-0.20.30.4-0.51.0-1.0-1.01.0-1.1
Total heroin consumption0.81.05.11.31.20.2-2.30.7-0.60.5-1.20.4-2.11.3-1.10.5-0.60.40.4-1.00.3-0.3-0.30.30.7
Bone: trabecular number0.81.44.31.41.42.1-1.51.7-1.71.8-1.1-1.0-1.00.5-0.61.2-0.00.20.10.5-1.01.01.0-1.00.8
Bone: trabecular spacing0.30.40.90.50.5-0.6-0.2-0.30.3-0.3-0.1-0.2-0.10.6-0.3-0.9-0.70.60.6-0.90.8-0.8-0.80.8-0.9
Bone: trabecular thickness1.82.26.01.41.32.5-1.02.3-2.32.3-1.8-0.7-1.50.9-1.11.5-0.10.20.00.4-1.31.31.3-1.32.2
Bone: trabecular tissue density0.30.42.30.40.4-0.30.20.3-0.40.4-0.20.1-0.30.10.30.90.8-0.9-0.90.5-0.80.80.8-0.81.5
Water consumed over 24 hours1.52.05.91.81.71.4-2.41.9-1.91.9-1.8-0.5-2.11.9-1.50.1-1.31.21.1-0.9-0.20.20.2-0.20.3
Number of responses in last shaping day0.40.41.2-0.4-0.4-0.30.7-0.40.5-0.5-0.3-0.3-0.30.5-0.7-0.8-0.70.70.7-1.10.9-0.9-0.90.9-0.3