Hub : Genes

Arhgap8

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative TSS XM_017594772.2 0.05 0.04 1.4e-04 0.01 0.02 0.02 0.02 1.0e-02 5.1e-03 3.1e-03 1.6e-03
2 Adipose alternative TSS XM_039078844.1 0.05 0.04 1.4e-04 0.01 0.02 0.02 0.02 9.5e-03 4.9e-03 4.1e-03 1.9e-03
3 Adipose alternative TSS XM_039078844.1 0.04 0.03 2.3e-04 0.01 0.02 0.01 0.02 8.3e-03 6.4e-03 8.0e-03 3.3e-03
4 Adipose gene expression Arhgap8 0.11 0.06 5.1e-11 0.07 0.05 0.06 0.05 4.9e-08 5.0e-06 2.1e-07 4.3e-06
5 Adipose isoform ratio XM_039078844.1 0.04 0.03 4.9e-04 0.02 0.01 0.01 0.02 6.5e-03 1.2e-02 6.8e-03 5.9e-03
6 Liver mRNA stability Arhgap8 0.44 0.18 5.5e-12 0.08 0.08 0.07 0.06 6.7e-09 2.8e-09 3.7e-08 7.1e-07
7 NAcc gene expression Arhgap8 0.03 0.02 2.2e-04 0.03 0.03 0.03 0.03 1.3e-04 2.8e-04 2.0e-04 1.6e-04
8 pVTA gene expression Arhgap8 0.1 0.06 1.1e-03 0.06 0.07 0.06 0.05 1.1e-03 8.4e-04 1.1e-03 3.1e-03
9 Liver gene expression Arhgap8 0.13 0.08 3.9e-13 0.06 0.03 0.07 0 3.5e-07 6.5e-04 1.7e-08 2.9e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.61.11.9-1.31.31.31.41.2-0.30.6-0.90.5
Area under the delay curve2.22.33.8-2.02.02.01.41.8-1.40.6-0.71.1
BMI with tail2.27.39.53.0-3.0-3.0-3.1-3.12.3-2.02.8-1.7
BMI without tail1.42.94.92.2-2.2-2.2-2.0-2.20.8-1.11.0-0.7
Body weight1.14.56.32.5-2.5-2.5-2.4-2.51.7-1.61.7-1.4
Weight adjusted by age0.80.91.71.1-1.1-1.1-1.3-1.10.4-0.70.6-0.7
Bone surface0.10.20.5-0.50.50.50.70.70.10.1-0.30.3
Bone volume0.20.40.9-0.80.80.80.90.70.20.2-0.50.2
Breakpoint value in progressive ratio session0.20.20.40.4-0.4-0.4-0.4-0.40.5-0.60.4-0.1
Number of licking bursts1.21.42.0-1.21.21.21.11.3-1.11.2-1.40.9
Context. condit. distance diff. score3.13.84.62.1-2.1-2.1-2.0-2.22.0-1.61.7-1.5
Locomotion velocity, session 12.02.25.01.2-1.2-1.2-1.6-1.11.8-2.21.3-1.4
Locomotion distance, session 10.10.10.2-0.50.50.50.40.50.3-0.3-0.10.0
Locomotion velocity, session 23.23.85.62.1-2.1-2.1-2.4-2.11.6-2.21.2-1.4
Locomotion distance, session 20.00.00.1-0.00.00.0-0.00.10.1-0.10.4-0.1
Locomotion velocity, session 31.72.02.91.5-1.5-1.5-1.7-1.71.4-1.30.7-1.1
Locomotion distance, session 30.20.31.0-0.20.20.20.20.1-0.60.8-1.00.6
Stereotopy head waving bouts, day 32.73.23.91.8-1.8-1.8-1.9-1.72.0-1.91.8-1.0
Stereotopy head waving duration, day 34.45.27.52.3-2.3-2.3-2.3-2.22.6-2.72.0-1.6
Locomotion velocity, session 70.70.71.61.0-1.0-1.0-1.0-1.30.1-0.30.3-0.7
Locomotion distance, session 70.10.10.3-0.10.10.10.0-0.2-0.40.6-0.2-0.1
Stereotopy head waving bouts, day 73.94.45.72.3-2.3-2.3-2.4-2.12.3-1.91.3-1.5
Stereotopy head waving duration, day 71.41.72.31.5-1.5-1.5-1.5-1.31.4-1.30.6-0.7
Locomotion velocity, session 89.911.914.23.6-3.6-3.6-3.8-3.63.4-3.43.0-2.9
Locomotion distance, session 82.02.93.81.9-1.9-1.9-1.8-1.91.6-1.31.4-1.3
Degree of sensitization distance1.21.22.80.8-0.8-0.8-1.0-1.11.1-1.21.7-1.2
Degree of sensitization stereotypy1.41.62.11.4-1.4-1.4-1.5-1.31.4-1.20.6-0.8
Conditioned locomotion0.50.61.0-0.70.70.70.70.4-1.01.0-0.70.8
Cocaine response after cond. corrected0.50.50.8-0.80.80.80.50.8-0.30.8-0.90.1
Cocaine response after cond. not corrected0.70.81.8-1.01.01.00.70.9-0.40.9-1.30.2
Cocaine response before conditioning0.20.20.4-0.50.50.50.60.3-0.40.5-0.60.3
Saline control response0.40.51.0-0.80.80.80.80.60.00.0-1.00.5
Bone: connectivity density0.30.40.8-0.70.70.70.90.8-0.20.3-0.70.5
Bone: cortical apparent density0.60.81.4-1.11.11.10.91.2-0.70.3-0.10.5
Bone: cortical area0.20.30.60.7-0.7-0.7-0.5-0.80.6-0.40.4-0.4
Bone: cortical porosity0.00.00.10.1-0.1-0.1-0.2-0.30.1-0.00.1-0.0
Bone: cortical porosity0.10.20.30.4-0.4-0.4-0.5-0.50.3-0.30.3-0.3
Bone: cortical thickness0.10.20.5-0.60.60.60.70.6-0.10.60.10.1
Bone: cortical thickness0.10.10.40.1-0.1-0.10.0-0.30.30.10.6-0.1
Bone: cortical tissue density0.40.51.0-1.01.01.00.71.0-0.50.20.00.4
Condit. Reinf. active minus inactive responses1.31.52.5-1.31.31.31.21.2-1.61.2-0.81.1
Condit. Reinf. active-inactive response ratio1.21.31.7-1.31.31.31.21.3-1.10.9-0.60.9
Condit. Reinf. active responses1.62.04.0-1.31.31.31.41.3-2.01.5-1.21.4
Condit. Reinf. inactive responses0.30.31.0-0.30.30.30.60.4-1.00.7-0.70.6
Incentive salience index mean1.31.62.9-1.21.21.21.31.1-1.71.4-1.01.1
Condit. Reinf. lever presses0.40.61.4-0.60.60.60.70.4-1.11.2-0.80.5
Condit. Reinf. active minus inactive responses0.20.30.90.4-0.4-0.4-0.5-0.50.4-1.00.7-0.2
Condit. Reinf. active-inactive response ratio0.10.10.4-0.20.20.2-0.0-0.10.4-0.60.2-0.3
Condit. Reinf. active responses1.62.34.31.5-1.5-1.5-1.5-1.51.1-2.11.6-1.0
Condit. Reinf. inactive responses2.43.04.01.9-1.9-1.9-1.7-1.91.2-2.01.8-1.1
Condit. Reinf. lever presses0.91.21.71.3-1.3-1.3-1.2-1.30.5-1.31.0-0.6
Condit. Reinf. lever reinforcers received1.01.43.11.2-1.2-1.2-1.2-1.20.7-1.81.3-0.8
Conditioned reinforcement - actives0.40.40.6-0.60.60.60.80.7-0.70.7-0.50.2
Conditioned reinforcement - inactives0.10.10.20.2-0.2-0.20.0-0.30.5-0.40.20.1
Conditioned locomotion0.81.02.20.9-0.9-0.9-0.9-0.81.5-1.20.4-0.9
Patch foraging indifference point 0 sec0.20.30.8-0.70.70.70.40.9-0.10.4-0.50.4
Patch foraging indifference point AUC0.00.10.2-0.10.10.10.30.1-0.00.40.30.4
Delay disc. indifference point, 0s delay0.00.10.3-0.10.10.1-0.40.20.0-0.50.2-0.0
Delay disc. indifference point, 16s delay3.63.66.0-2.42.42.41.52.4-1.71.2-1.11.1
Delay disc. indifference point, 2s delay0.50.60.9-1.01.01.00.90.9-0.70.1-0.30.6
Delay disc. indifference point, 24s delay0.30.20.6-0.60.60.60.10.5-0.80.30.10.5
Delay disc. indifference point, 4s delay0.90.91.7-1.31.31.30.71.30.1-0.90.30.1
Delay disc. indifference point, 8s delay1.81.94.2-1.31.31.31.11.2-2.11.4-0.91.5
Indifference point function ln k0.71.01.41.1-1.1-1.1-1.2-1.10.8-0.90.3-1.0
Indifference point function log k0.71.01.41.1-1.1-1.1-1.2-1.10.8-0.90.3-1.0
Patch foraging total patch changes 0 sec0.40.61.3-0.90.90.90.61.1-0.30.5-0.70.5
Patch foraging total patch changes 12 sec0.10.10.50.0-0.0-0.0-0.3-0.10.30.10.70.0
Patch foraging total patch changes 18 sec1.21.52.6-1.51.51.51.61.60.10.6-0.71.0
Patch foraging total patch changes 24 sec0.00.00.2-0.10.10.10.10.30.20.1-0.40.2
Patch foraging total patch changes 6 sec0.30.51.1-0.80.80.80.81.0-0.10.6-0.20.5
Patch foraging time to switch 0 sec0.10.10.40.0-0.0-0.1-0.2-0.4-0.2-0.1-0.10.6
Patch foraging water rate 0 sec0.20.40.90.7-0.7-0.7-0.5-0.30.7-0.10.4-0.9
Patch foraging water rate 12 sec0.10.20.50.2-0.2-0.2-0.20.30.7-0.4-0.7-0.5
Patch foraging water rate 18 sec0.10.10.5-0.10.10.10.30.30.10.1-0.2-0.7
Patch foraging water rate 24 sec0.91.21.81.2-1.2-1.2-1.1-0.81.3-0.90.8-1.3
Patch foraging water rate 6 sec0.10.20.5-0.30.30.30.70.5-0.40.3-0.7-0.4
Seeking ratio, delayed vs. immediate footshock1.61.82.9-1.01.01.01.51.0-1.71.7-1.61.5
Distance traveled before self-admin0.00.00.10.1-0.1-0.10.1-0.20.10.20.30.1
Distance traveled after self-admin0.80.92.50.9-0.9-0.9-0.5-0.81.6-1.10.6-0.5
Extensor digitorum longus weight0.20.81.41.1-1.1-1.1-1.1-1.20.4-0.50.4-0.7
Bone: elastic displacement0.80.92.30.7-0.7-0.7-0.9-0.51.2-1.50.3-1.4
Bone: elastic work3.84.96.22.2-2.2-2.2-2.3-2.12.5-2.41.6-2.3
Bone: endosteal estimation2.65.67.32.7-2.7-2.7-2.6-2.62.1-2.21.4-1.8
Bone: endosteal perimeter1.53.04.82.2-2.2-2.2-1.9-2.21.2-1.50.3-1.0
Epididymis fat weight0.20.51.00.5-0.5-0.5-1.0-0.50.6-0.80.7-0.7
Delta time in closed arm before/after self-admin0.40.30.8-0.50.50.50.30.30.8-0.90.6-0.6
Delta time in open arm before/after self-admin0.40.30.60.7-0.7-0.7-0.8-0.60.4-0.5-0.3-0.2
Diff in mean of infusions in LGA sessions0.30.31.1-0.50.50.51.00.4-0.40.30.50.5
Delay discount exponential model param2.12.23.82.0-2.0-2.0-1.4-1.81.3-0.50.6-1.0
Extinction: sum of active levers before priming0.10.10.50.2-0.2-0.1-0.50.0-0.1-0.20.6-0.7
Active lever presses in extinction session 60.90.81.50.9-0.9-0.9-1.0-1.00.5-1.01.2-0.4
Bone: final force0.81.22.71.0-1.0-1.0-0.9-1.01.2-1.11.6-1.0
Bone: final moment1.21.93.91.3-1.3-1.3-1.2-1.21.5-1.32.0-1.3
Food consumed during 24 hour testing period2.32.84.11.6-1.6-1.6-1.6-1.62.0-1.71.9-1.4
Glucose2.02.94.2-2.12.12.11.91.7-1.31.4-1.11.5
Heart weight0.10.20.4-0.40.40.40.20.30.7-0.60.3-0.2
Delay discount hyperbolic model param1.71.83.11.8-1.8-1.8-1.3-1.71.1-0.30.5-0.9
Intermittent access intake day 1-15 change0.40.40.6-0.70.70.70.60.5-0.70.8-0.70.4
Intermittent access intake escalation0.40.40.8-0.60.60.60.40.4-0.90.7-0.80.5
Intermittent access intake escalation 20.50.40.7-0.80.80.80.60.7-0.60.6-0.50.3
Intermitt. access day 1 inactive lever presses1.82.03.51.3-1.3-1.3-1.2-1.31.9-1.81.5-0.8
Intermitt. access day 15 inactive lever presses1.82.04.01.1-1.1-1.1-1.3-1.21.7-1.52.0-1.2
Intermitt. access escalation Index0.00.00.0-0.00.00.0-0.10.1-0.1-0.2-0.00.2
Intermittent access day 1 total infusions0.80.91.61.3-1.3-1.2-0.7-1.10.6-0.60.7-0.8
Intermittent access day 15 total infusions0.20.20.40.6-0.6-0.6-0.5-0.6-0.0-0.10.0-0.3
Intermittent access terminal intake (last 3 days)0.40.40.80.9-0.9-0.9-0.7-0.90.2-0.20.4-0.4
Intermittent access total infusions0.50.51.01.0-1.0-1.0-0.8-1.00.0-0.30.3-0.3
Intermittent access day 1 locomotion0.10.10.10.3-0.3-0.3-0.1-0.3-0.10.2-0.3-0.1
Intermittent access day 15 total locomotion0.60.61.21.1-1.1-1.1-0.7-1.00.4-0.2-0.1-0.5
Intermittent access total locomotion1.21.32.21.5-1.5-1.5-1.2-1.40.6-0.60.5-1.0
Intermittent access standard deviation0.70.70.90.8-0.8-0.8-0.9-1.00.7-0.80.9-0.9
Left kidney weight14.139.748.86.6-6.6-6.6-7.0-6.76.3-5.85.9-5.1
Right kidney weight14.440.345.76.6-6.6-6.6-6.8-6.66.7-6.16.1-5.0
Cocaine induced anxiety4.55.27.52.5-2.5-2.5-2.7-2.41.7-2.02.3-1.8
Post-drug Anxiety2.22.53.71.5-1.5-1.5-1.9-1.51.4-1.71.8-1.1
Baseline Anxiety4.04.25.7-2.42.42.42.22.3-1.71.7-1.81.6
Tail length0.10.20.8-0.40.40.40.40.4-0.50.2-0.90.3
Length with tail0.00.10.20.2-0.2-0.2-0.1-0.30.3-0.4-0.1-0.2
Length without tail0.40.81.80.6-0.6-0.6-0.6-0.61.4-1.01.2-0.9
Times rat made contact with spout0.80.92.10.6-0.6-0.6-0.7-0.51.4-1.41.2-0.8
Lifetime Intake0.70.81.41.1-1.1-1.2-0.9-1.20.3-0.50.4-0.5
Liver weight, left0.50.82.30.7-0.7-0.7-0.6-0.90.8-1.51.1-0.6
Liver weight, right0.10.10.50.4-0.4-0.4-0.3-0.7-0.1-0.30.0-0.3
Locomotor activity0.91.52.61.3-1.3-1.3-1.1-1.41.6-0.60.9-1.2
Locomotor testing distance0.00.10.2-0.20.20.20.40.20.10.5-0.30.2
Locomotor testing rearing0.00.10.30.2-0.2-0.2-0.2-0.20.5-0.2-0.1-0.1
Locomotion in novel chamber1.11.34.0-0.90.90.91.10.9-0.90.8-2.01.5
Locomotion in novel chamber post-restriction0.40.41.2-0.10.10.10.7-0.1-1.00.6-0.81.1
Fecal boli incidents, locomotor time 10.50.50.90.9-0.9-0.9-0.7-0.90.4-0.50.6-0.5
Change in fecal boli incidents, locomotor task0.10.10.4-0.10.10.10.20.4-0.30.2-0.60.2
Time >=10cm from walls, locomotor time 10.50.50.80.8-0.8-0.8-0.6-0.90.4-0.60.6-0.8
Bouts of movement, locomotor time 10.00.00.1-0.10.10.1-0.2-0.2-0.20.10.4-0.2
Total resting periods, locomotor time 10.10.10.2-0.40.40.40.00.1-0.40.20.4-0.1
Rest time, locomotor task time 10.50.60.90.9-0.9-0.9-1.0-0.80.2-0.40.8-0.6
Distance moved, locomotor task time 10.10.10.30.2-0.2-0.20.4-0.20.5-0.4-0.10.3
Vertical activity count, locomotor time 10.10.10.5-0.30.30.30.70.40.2-0.3-0.30.2
Time >=10cm from walls, locomotor time 20.10.10.5-0.00.00.00.00.2-0.70.1-0.5-0.1
Bouts of movement, locomotor time 20.30.31.0-0.50.50.50.30.3-1.01.00.20.1
Total resting periods, locomotor time 20.30.31.2-0.40.40.40.20.2-1.01.10.30.1
Rest time, locomotor task time 20.20.30.5-0.50.50.60.40.7-0.50.5-0.30.0
Distance moved, locomotor task time 21.21.42.21.5-1.5-1.5-1.1-1.51.0-1.10.5-0.6
Vertical activity count, locomotor time 21.51.72.31.5-1.5-1.5-1.4-1.51.0-1.10.6-1.3
Light reinforcement 10.61.02.81.0-1.0-1.0-0.8-0.91.7-1.40.0-0.6
Light reinforcement 21.21.62.51.6-1.6-1.6-1.5-1.60.8-1.00.3-0.6
Bone: marrow area2.75.87.62.8-2.8-2.8-2.7-2.72.1-2.31.5-1.8
Bone: maximum diameter3.56.49.02.9-2.9-2.9-2.6-3.02.4-2.31.7-1.8
Bone: maximum force1.52.63.91.6-1.6-1.6-1.5-1.51.7-1.42.0-1.4
Bone: maximum moment2.03.55.21.8-1.8-1.8-1.9-1.82.0-1.72.3-1.7
Mean time between licks in bursts2.73.94.4-2.12.12.12.01.8-2.01.9-2.01.5
Mean num. licks in bursts3.23.96.01.8-1.8-1.8-1.8-1.72.2-2.52.4-1.5
Cd content in liver0.20.20.4-0.60.60.60.50.6-0.40.0-0.20.0
Co content in liver0.40.42.20.4-0.4-0.4-0.4-0.41.5-0.60.3-0.7
Cu content in liver5.26.37.9-2.42.42.42.52.5-2.82.4-2.82.3
Fe content in liver0.20.20.8-0.40.40.40.40.30.9-0.6-0.20.3
K content in liver0.60.61.00.6-0.6-0.6-0.8-0.50.9-1.00.9-0.7
Mg content in liver0.10.10.30.1-0.1-0.1-0.30.00.3-0.50.5-0.3
Mn content in liver0.60.70.90.8-0.8-0.8-1.0-0.91.0-0.80.6-0.8
Na content in liver2.52.64.0-1.51.51.51.71.4-1.92.0-1.31.6
Rb content in liver0.20.30.6-0.60.60.60.70.8-0.50.2-0.30.4
Se content in liver0.10.10.2-0.40.40.40.30.4-0.10.1-0.50.3
Sr content in liver0.50.50.9-0.70.70.70.70.5-0.80.9-0.70.6
Zn content in liver1.01.11.5-1.21.21.21.21.0-0.91.0-1.20.4
Bone: minimum diameter0.30.61.31.0-1.0-1.0-0.8-1.10.6-0.3-0.3-0.5
Time in familiar zone, hab. session 10.80.81.50.8-0.8-0.8-0.8-0.91.0-1.20.6-0.7
Time in novel zone, hab. session 10.70.61.5-0.80.80.80.70.8-0.51.2-0.70.8
Total zone transitions, hab. session 11.52.12.7-1.61.61.61.51.4-1.21.5-1.11.4
Total locomotion distance, hab. session 10.00.10.10.3-0.3-0.3-0.4-0.30.10.1-0.20.1
Locomotion velocity, hab. session 10.10.10.30.5-0.5-0.5-0.5-0.50.2-0.1-0.0-0.2
Time in familiar zone, hab. session 20.10.10.2-0.30.30.30.10.4-0.2-0.3-0.4-0.4
Time in novel zone, hab. session 20.10.10.3-0.10.10.10.30.20.30.50.10.6
Total zone transitions, hab. session 20.60.81.50.7-0.7-0.7-0.7-0.71.2-1.21.1-0.8
Total locomotion distance, hab. session 20.40.50.60.8-0.8-0.8-0.7-0.70.7-0.50.5-0.6
Locomotion velocity, hab. session 20.30.40.50.7-0.7-0.7-0.6-0.60.6-0.50.5-0.5
Novel to familiar place preference ratio0.20.20.30.5-0.5-0.5-0.4-0.10.5-0.30.3-0.6
Novelty place preference0.40.40.60.7-0.7-0.7-0.6-0.30.7-0.60.4-0.8
Time in novel zone, NPP test0.40.40.80.7-0.7-0.7-0.6-0.40.9-0.60.4-0.8
Total zone transitions, NPP test0.00.00.1-0.20.20.20.20.40.20.10.1-0.3
Total locomotion distance, NPP test0.20.30.50.7-0.7-0.7-0.6-0.50.7-0.40.1-0.6
Locomotion velocity, NPP test0.10.10.20.4-0.4-0.4-0.4-0.30.1-0.1-0.2-0.4
Intraocular pressure0.00.00.0-0.10.10.1-0.2-0.2-0.10.0-0.2-0.1
Delta distance traveled before/after self-admin1.61.74.11.1-1.1-1.1-1.0-0.92.0-2.00.6-1.1
Delta ambulatory time before/after self-admin1.11.23.40.8-0.8-0.8-0.7-0.51.8-1.80.5-1.0
Parametrial fat weight0.10.20.4-0.60.60.60.40.40.5-0.2-0.0-0.0
Pavlov. Cond. lever latency1.21.52.11.4-1.4-1.4-1.4-1.01.2-0.81.3-0.9
Pavlov. Cond. magazine entry latency2.93.75.0-2.22.22.22.21.8-1.71.9-1.41.6
Pavlov. Cond. change in total contacts2.93.14.2-2.02.02.02.01.7-1.51.4-1.31.6
Pavlov. Cond. index score1.92.33.2-1.81.81.81.71.3-1.41.4-1.21.3
Pavlov. Cond. latency score1.31.62.3-1.51.51.51.51.1-1.11.1-1.11.0
Pavlov. Cond. lever contacts1.82.12.6-1.61.61.61.61.1-1.41.3-1.51.1
Pavlov. Cond. magazine entry number2.83.54.52.1-2.1-2.0-2.1-1.71.9-1.91.4-1.7
Pavlov. Cond. intertrial magazine entries0.20.21.1-0.50.50.50.61.0-0.10.1-0.30.0
Pavlov. Cond. lever-magazine prob. diff.2.63.24.1-2.02.02.01.91.6-1.71.7-1.41.5
Pavlov. Cond. response bias3.64.45.3-2.32.32.32.31.8-2.12.1-1.71.8
Pavlov. Cond. lever latency0.50.61.6-0.80.80.80.60.7-0.71.3-0.60.5
Pavlov. Cond. magazine entry latency0.10.10.4-0.40.40.40.40.7-0.5-0.20.00.3
Pavlov. Cond. change in total contacts0.60.92.30.7-0.7-0.7-0.6-0.71.2-1.51.2-0.6
Pavlov. Cond. index score0.10.10.70.2-0.2-0.2-0.1-0.10.1-0.80.4-0.1
Pavlov. Cond. latency score0.10.10.60.3-0.3-0.3-0.1-0.20.1-0.80.4-0.1
Pavlov. Cond. lever contacts0.60.81.60.9-0.9-0.9-0.8-0.80.8-1.30.9-0.6
Pavlov. Cond. magazine entry number0.10.10.7-0.20.20.20.00.0-0.20.8-0.40.0
Pavlov. Cond. intertrial magazine entries0.50.71.30.9-0.9-0.9-0.8-1.00.6-0.51.2-0.6
Pavlov. Cond. lever-magazine prob. diff.0.10.10.60.3-0.3-0.3-0.1-0.10.1-0.80.4-0.2
Pavlov. Cond. response bias0.30.41.10.5-0.5-0.5-0.5-0.40.5-1.00.8-0.5
Time in closed arm before self-admin1.51.73.0-1.11.11.11.21.3-1.71.6-1.31.3
Time in closed arm after self-admin0.80.81.4-1.21.21.21.11.0-0.10.2-0.70.6
Time in open arm before self-admin0.10.10.20.3-0.3-0.30.0-0.4-0.40.1-0.2-0.0
Time in open arm after self-admin1.41.52.81.7-1.7-1.7-1.6-1.40.1-0.60.4-0.6
Bone: periosteal estimation1.73.64.82.2-2.2-2.2-2.0-2.21.8-1.71.2-1.4
Bone: periosteal perimeter1.11.83.31.8-1.8-1.8-1.4-1.80.9-0.80.2-0.7
Bone: post-yield work0.10.21.0-0.20.20.20.10.30.40.01.0-0.0
Progressive ratio test 1 active lever presses0.10.20.50.4-0.4-0.40.1-0.3-0.70.6-0.1-0.1
Progressive ratio test 1 breakpoint0.20.20.80.2-0.2-0.20.4-0.2-0.90.8-0.20.2
Progressive ratio test 1 inactive lever presses0.10.10.30.4-0.4-0.4-0.3-0.50.3-0.30.5-0.4
Progressive ratio test 2 active lever presses1.11.11.81.3-1.3-1.3-0.9-1.00.7-0.81.3-0.9
Progressive ratio test 2 breakpoint1.21.42.11.4-1.4-1.4-1.0-1.10.7-0.81.4-1.0
Progressive ratio test 2 inactive lever presses1.11.31.81.3-1.3-1.3-1.0-1.20.8-1.11.3-0.8
Incentive Sensitization - Responses3.03.14.81.7-1.7-1.7-1.7-1.51.9-1.82.2-1.5
Incentive Sensitization - Breakpoint3.63.65.51.8-1.8-1.8-1.9-1.62.0-2.02.3-1.7
Sum of active levers in priming session hrs 5-60.50.50.70.7-0.7-0.7-0.9-0.80.4-0.30.7-0.7
Progressive ratio0.20.30.5-0.50.50.50.60.4-0.70.7-0.1-0.4
Food seeking constrained by brief footshock0.40.52.10.4-0.4-0.4-0.2-0.61.4-0.80.5-0.7
Seeking ratio, punishment vs. effort0.50.61.90.7-0.7-0.7-0.7-0.71.4-1.10.60.1
Retroperitoneal fat weight1.23.85.32.0-2.0-2.0-2.3-2.31.8-1.81.8-1.3
Reaction time number correct0.50.71.9-0.30.30.40.90.7-1.41.4-1.10.3
Reaction time mean minus median0.00.00.20.2-0.2-0.20.20.0-0.00.4-0.0-0.1
Reaction time mean minus median AUC0.60.71.51.2-1.2-1.2-0.8-0.90.2-0.10.6-0.7
Reaction time num false alarms1.01.42.4-1.11.11.11.60.9-0.51.5-1.31.2
Reaction time num false alarms AUC0.71.02.1-0.90.90.91.40.8-0.11.3-1.00.8
Reaction time trials correct on left0.50.71.9-0.30.30.40.90.7-1.41.4-1.10.3
Reaction time trials on left0.60.82.1-0.40.40.40.90.8-1.41.4-1.10.3
Reaction time mean0.40.50.8-0.60.60.60.90.8-0.90.9-0.30.7
Reaction time mean AUC0.30.40.9-0.50.50.50.80.7-1.00.8-0.30.5
Median of all reaction times0.71.01.4-1.11.11.11.21.1-1.00.8-0.40.8
Reaction time omissions0.81.12.1-1.11.11.10.91.2-1.21.4-0.60.6
Reaction time false alarm rate0.30.40.8-0.70.70.70.90.40.40.6-0.50.7
Reaction time premature initiation rate1.72.23.91.7-1.7-1.7-1.7-1.40.9-1.12.0-0.8
Reaction time premature initiations0.71.01.81.3-1.3-1.3-1.1-0.90.2-0.41.3-0.6
Std. dev. reaction times0.00.10.30.1-0.1-0.10.30.2-0.30.5-0.0-0.0
Reaction time trials completed0.60.82.1-0.40.40.40.90.8-1.41.4-1.10.3
Reaction time trials AUC0.40.51.5-0.10.10.10.70.5-1.21.2-0.90.2
Run reversals in cocaine runway, females3.43.34.5-1.91.91.91.71.9-1.41.5-2.11.8
Run reversals in cocaine runway, males0.30.30.50.7-0.7-0.7-0.4-0.70.6-0.30.1-0.3
Latency to leave start box in cocaine runway1.21.31.91.0-1.0-1.0-1.2-1.11.3-1.40.9-1.2
Latency to leave start box in cocaine runway, F0.30.30.90.5-0.5-0.5-0.3-0.40.9-0.50.6-0.8
Latency to leave start box in cocaine runway, M1.61.62.91.0-1.0-1.0-1.6-1.21.1-1.71.1-1.3
Std. dev. time between licks in bursts0.10.10.7-0.10.10.10.10.1-0.90.5-0.20.5
Total sessions with >9 infusions0.20.20.60.6-0.6-0.6-0.2-0.7-0.10.3-0.50.2
Short access day 1 total inactive lever presses2.42.66.21.5-1.5-1.5-1.4-1.62.5-1.91.4-0.9
Short access day 10 total inactive lever presses2.32.66.71.1-1.1-1.1-1.5-1.22.6-2.51.5-0.9
Short access day 1 total infusions0.70.82.30.8-0.8-0.8-0.4-1.01.5-1.10.6-0.6
Short access day 10 total infusions0.30.31.30.4-0.4-0.40.1-0.5-1.10.7-0.40.4
Short access total infusions0.80.92.21.2-1.2-1.2-0.9-1.50.4-0.60.5-0.5
Short access day 1 locomotion0.10.10.3-0.20.20.20.50.10.4-0.1-0.40.2
Short access day 10 total locomotion0.70.81.6-0.80.80.81.00.5-1.01.2-1.10.4
Short access total locomotion0.10.10.30.0-0.0-0.00.3-0.3-0.30.6-0.60.4
One hour access (0.3 mA shock)0.30.30.70.8-0.8-0.8-0.4-0.7-0.30.0-0.1-0.2
Compulsive drug intake0.20.20.40.1-0.1-0.1-0.30.00.6-0.50.6-0.5
One hour access (shock baseline)0.30.41.30.2-0.2-0.20.0-0.3-1.10.7-0.90.6
Social response proportion0.20.20.70.4-0.4-0.4-0.5-0.50.8-0.40.4-0.3
Social responses0.30.40.60.8-0.8-0.8-0.8-0.70.4-0.40.3-0.5
Social time2.33.14.4-2.12.12.12.12.0-1.21.3-1.11.3
Soleus weight0.20.71.90.7-0.7-0.7-0.6-0.70.8-0.61.4-1.0
Bone: stiffness0.10.10.4-0.20.20.20.20.10.10.30.60.4
Tibialis anterior weight0.00.00.0-0.10.10.1-0.00.1-0.10.10.1-0.1
Time to tail flick, vehicle, before self-admin0.30.30.50.6-0.6-0.6-0.5-0.30.4-0.20.6-0.7
Time to tail flick, vehicle, after self-admin0.10.10.50.1-0.1-0.0-0.00.2-0.70.3-0.40.3
Time to tail flick, test, before self-admin0.10.10.30.1-0.1-0.10.2-0.30.2-0.5-0.1-0.2
Time to tail flick, test, after self-admin1.71.82.4-1.41.41.41.51.5-0.91.1-1.11.3
Delta time to tail flick, vehicle, before/after SA0.20.20.40.3-0.3-0.3-0.3-0.40.5-0.60.6-0.1
Delta time to tail flick, test, before/after SA1.31.22.3-1.21.21.21.11.5-0.61.0-0.80.9
Tibia length0.10.41.10.4-0.4-0.4-0.6-0.31.0-0.70.7-0.6
Ambulatory time before self-admin0.10.10.40.2-0.2-0.2-0.0-0.40.6-0.40.5-0.0
Ambulatory time after self-admin0.30.41.70.3-0.3-0.3-0.1-0.11.3-1.10.3-0.3
Bone: tissue strength0.30.30.90.2-0.2-0.2-0.50.10.5-1.00.7-0.7
Total heroin consumption1.31.52.21.5-1.5-1.5-1.1-1.40.8-0.81.3-0.8
Bone: trabecular number1.32.02.7-1.61.61.61.71.4-0.91.5-1.60.9
Bone: trabecular spacing3.24.15.82.3-2.3-2.3-2.2-2.41.4-1.81.9-1.4
Bone: trabecular thickness0.30.30.6-0.60.60.60.70.6-0.00.6-0.60.4
Bone: trabecular tissue density0.20.20.3-0.60.60.60.40.5-0.20.60.20.4
Water consumed over 24 hours2.32.74.01.7-1.7-1.7-1.6-1.42.0-1.81.6-1.3
Number of responses in last shaping day0.80.82.1-1.01.01.01.50.8-0.10.4-0.50.7