Arhgap45

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc isoform ratio XM_039078980.2 0.03 0.02 7.1e-03 0.01 0.01 0.02 0.01 3.2e-03 2.0e-02 1.1e-03 1.1e-02
2 Brain alternative TSS XM_039078979.2 0.03 0.03 1.8e-03 0.03 0.02 0.02 0.02 4.4e-04 2.9e-03 9.2e-03 3.3e-03
3 Brain alternative TSS XM_039078979.2 0.04 0.03 1.6e-03 0.03 0.02 0.01 0.03 3.8e-04 7.7e-03 1.6e-02 1.9e-03
4 Brain isoform ratio XM_039078978.2 0.03 0.02 1.8e-03 0.02 0.02 0.01 0.02 7.4e-03 4.1e-03 2.8e-02 7.3e-03
5 NAcc alternative TSS XM_039078979.2 0.03 0.02 4.3e-06 0.03 0.04 0.03 0.03 5.8e-05 4.1e-06 5.1e-06 7.4e-06
6 NAcc isoform ratio XM_039078978.2 0.02 0.02 1.7e-04 0.02 0.02 0.02 0.02 1.0e-03 4.0e-04 9.2e-04 7.8e-04
7 Adipose intron excision ratio chr7_10339856_10340711 0.02 0.02 5.9e-03 0.01 0.01 0.01 0.01 3.7e-02 1.5e-02 1.1e-02 3.5e-02
8 NAcc alternative TSS XM_039078979.2 0.04 0.03 1.7e-07 0.04 0.05 0.05 0.04 1.0e-06 1.5e-07 1.6e-07 2.2e-07
9 Adipose intron excision ratio chr7_10339856_10340526 0.02 0.02 7.4e-03 0.01 0.01 0.01 0.01 1.8e-02 1.7e-02 1.0e-02 3.2e-02
10 NAcc gene expression Arhgap45 0.01 0.01 3.9e-03 0.01 0.01 0.01 0 2.8e-02 2.2e-02 3.9e-02 4.9e-02
11 PL alternative TSS XM_039078979.2 0.02 0.02 5.0e-03 0.01 0.01 0 0.01 2.1e-02 1.8e-02 1.4e-01 2.6e-02
12 PL isoform ratio XM_039078978.2 0.02 0.02 5.2e-03 0.01 0.01 0.01 0.01 1.7e-02 9.3e-03 2.8e-02 1.3e-02
13 Brain mRNA stability Arhgap45 0.04 0.04 2.0e-03 0.02 0.01 0 0.01 2.3e-03 6.6e-02 3.2e-01 2.9e-02
14 pVTA gene expression Arhgap45 0.04 0.03 4.9e-03 0.01 0.01 0 0 2.0e-02 5.2e-02 1.9e-01 1.4e-01
15 pVTA isoform ratio XM_039078978.2 0.03 0.02 4.2e-03 0.01 0 0.01 0 2.0e-02 1.1e-01 6.0e-02 2.3e-01
16 Liver isoform ratio XM_039078978.2 0.04 0.03 1.4e-04 0.02 0.01 0.01 0.02 6.4e-03 1.1e-02 1.8e-02 3.7e-03
17 BLA gene expression Arhgap45 0.08 0.06 4.5e-04 0.06 0.06 0.05 0.06 3.3e-04 6.5e-04 7.7e-04 5.7e-04
18 NAcc intron excision ratio chr7_10339856_10340526 0.02 0.02 2.6e-04 0.03 0.02 0.02 0.03 6.5e-05 3.0e-04 1.9e-04 9.8e-05
19 NAcc intron excision ratio chr7_10339856_10340711 0.02 0.02 3.9e-04 0.02 0.02 0.02 0.02 1.5e-04 4.6e-04 3.4e-04 1.8e-04
20 Adipose alternative TSS XM_017594813.3 0.04 0.03 1.5e-04 0.03 0.03 0.03 0.03 2.3e-04 6.7e-04 8.0e-04 7.0e-04
21 Adipose alternative TSS XM_017594813.3 0.04 0.03 1.1e-04 0.03 0.03 0.03 0.03 1.6e-04 3.9e-04 4.5e-04 4.1e-04
22 Adipose alternative TSS XM_039078979.2 0.06 0.04 4.6e-06 0.05 0.04 0.04 0.05 3.8e-06 8.2e-06 1.1e-05 5.3e-06
23 Adipose alternative TSS XM_039078979.2 0.06 0.04 4.2e-06 0.05 0.05 0.04 0.05 3.6e-06 7.4e-06 9.6e-06 5.3e-06
24 Adipose isoform ratio NM_001108067.1 0.03 0.02 1.4e-03 0.03 0.02 0.01 0.02 6.3e-04 5.8e-03 2.9e-02 2.1e-03
25 Adipose isoform ratio XM_017594813.3 0.05 0.04 3.9e-05 0.04 0.03 0.04 0.04 4.0e-05 1.1e-04 8.6e-05 8.3e-05
26 RMTg alternative TSS XM_063263414.1 0.13 0.1 9.9e-03 0.07 0.04 0.09 0.05 8.2e-03 2.4e-02 2.8e-03 1.8e-02
27 Adipose isoform ratio XM_039078978.2 0.02 0.02 9.7e-03 0.01 0.01 0.01 0.01 7.7e-03 7.6e-03 2.0e-02 1.9e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27
Bone: apparent density0.40.73.71.90.70.70.2-0.0-0.20.1-0.3-0.2-0.4-0.5-0.6-0.8-0.7-0.7-0.5-0.7-0.70.70.70.7-0.7-0.70.70.71.7-1.7
Area under the delay curve1.92.32.7-0.5-1.6-1.6-1.6-1.6-1.61.5-1.6-1.5-1.6-1.6-1.6-1.5-1.6-1.6-1.6-1.4-1.41.41.61.6-1.6-1.61.61.61.0-1.3
BMI with tail6.121.125.1-0.8-4.8-4.8-4.9-4.9-4.95.0-4.9-5.0-4.9-4.8-4.8-4.8-4.6-4.6-4.7-4.6-4.64.64.64.6-4.6-4.64.64.63.9-3.6
BMI without tail1.85.67.6-1.3-2.8-2.8-2.7-2.7-2.62.6-2.6-2.6-2.5-2.5-2.4-2.3-2.4-2.4-2.4-2.3-2.32.32.32.3-2.3-2.32.32.31.6-1.5
Body weight0.93.84.5-0.4-2.1-2.1-2.1-2.1-2.12.1-2.1-2.1-2.1-2.1-2.1-2.1-2.1-2.1-2.0-1.9-1.91.91.91.9-1.9-1.91.91.91.6-1.6
Weight adjusted by age0.30.52.1-1.4-1.2-1.2-1.0-0.9-0.80.7-0.8-0.7-0.7-0.7-0.6-0.5-0.6-0.6-0.5-0.4-0.40.40.40.4-0.4-0.40.40.40.1-0.0
Bone surface0.61.011.63.41.81.81.10.80.6-0.50.50.40.30.10.0-0.4-0.3-0.3-0.1-0.3-0.30.30.30.3-0.3-0.30.30.31.6-1.7
Bone volume0.51.011.33.41.61.60.90.60.4-0.40.30.30.1-0.0-0.2-0.6-0.4-0.4-0.1-0.3-0.30.30.30.3-0.3-0.30.30.31.7-1.9
Breakpoint value in progressive ratio session3.84.55.01.21.91.92.12.12.2-2.22.22.22.22.22.22.22.22.22.22.22.2-2.2-2.2-2.22.22.2-2.2-2.2-1.92.0
Number of licking bursts0.20.35.5-2.3-0.9-0.9-0.5-0.4-0.30.2-0.2-0.2-0.2-0.1-0.00.10.10.10.10.20.2-0.2-0.2-0.20.20.2-0.2-0.2-0.20.7
Context. condit. distance diff. score0.30.31.2-1.1-0.5-0.5-0.5-0.5-0.50.5-0.5-0.6-0.5-0.5-0.5-0.1-0.7-0.7-0.6-0.6-0.60.60.70.7-0.7-0.70.70.7-0.1-0.2
Locomotion velocity, session 10.40.51.71.31.21.21.00.90.8-0.80.70.70.70.60.50.40.40.40.50.50.5-0.5-0.4-0.40.40.4-0.4-0.40.4-0.3
Locomotion distance, session 10.50.63.61.91.61.61.10.90.7-0.70.60.60.50.40.30.4-0.1-0.10.1-0.1-0.10.10.10.1-0.1-0.10.10.10.7-1.2
Locomotion velocity, session 23.84.510.32.23.23.22.92.72.5-2.52.52.32.32.22.12.11.71.71.91.71.7-1.7-1.6-1.61.61.6-1.6-1.6-1.40.6
Locomotion distance, session 21.52.26.32.52.52.52.11.91.7-1.71.61.61.51.41.21.01.11.11.21.01.0-1.0-1.0-1.01.01.0-1.0-1.00.2-0.4
Locomotion velocity, session 36.47.38.60.32.52.52.82.82.9-2.82.92.82.92.92.92.92.82.82.72.72.7-2.7-2.7-2.72.72.7-2.7-2.7-2.72.6
Locomotion distance, session 30.00.00.2-0.1-0.2-0.2-0.0-0.00.00.00.0-0.00.10.10.10.20.10.1-0.0-0.0-0.00.00.00.0-0.0-0.00.00.0-0.40.4
Stereotopy head waving bouts, day 35.15.98.10.32.92.92.92.82.8-2.72.72.72.72.62.62.52.52.52.42.32.3-2.3-2.3-2.32.32.3-2.3-2.3-1.61.7
Stereotopy head waving duration, day 36.37.59.20.13.03.03.03.03.0-3.03.03.03.02.92.92.82.92.92.82.72.7-2.7-2.7-2.72.72.7-2.7-2.7-2.02.1
Locomotion velocity, session 70.50.61.6-1.30.60.60.70.60.7-0.70.70.70.70.70.71.20.60.60.70.70.7-0.7-0.7-0.70.70.7-0.7-0.7-1.20.8
Locomotion distance, session 70.20.33.0-1.7-1.0-1.0-0.7-0.7-0.60.5-0.5-0.5-0.5-0.4-0.40.1-0.3-0.3-0.2-0.2-0.20.20.20.2-0.2-0.20.20.2-0.30.4
Stereotopy head waving bouts, day 70.10.21.80.20.50.50.30.20.1-0.10.10.10.0-0.0-0.1-0.3-0.1-0.1-0.2-0.3-0.30.30.30.3-0.3-0.30.30.31.4-0.7
Stereotopy head waving duration, day 70.30.41.30.61.11.10.90.80.7-0.80.70.70.60.50.50.10.40.40.40.30.3-0.3-0.2-0.20.20.2-0.2-0.21.0-0.4
Locomotion velocity, session 80.60.72.61.41.61.61.31.21.0-1.01.00.90.90.80.70.90.40.40.60.40.4-0.4-0.4-0.40.40.4-0.4-0.4-0.8-0.4
Locomotion distance, session 80.20.31.10.11.01.00.90.80.7-0.70.70.60.60.50.50.70.20.20.30.20.2-0.2-0.2-0.20.20.2-0.2-0.2-0.2-0.1
Degree of sensitization distance0.40.50.7-0.8-0.6-0.6-0.7-0.7-0.70.7-0.7-0.7-0.7-0.7-0.7-0.4-0.9-0.9-0.6-0.7-0.70.70.60.6-0.6-0.60.60.60.5-0.6
Degree of sensitization stereotypy1.92.15.90.0-1.0-1.0-1.2-1.2-1.31.3-1.3-1.3-1.4-1.4-1.4-1.7-1.5-1.5-1.5-1.5-1.51.51.51.5-1.5-1.51.51.52.4-1.6
Conditioned locomotion1.11.23.4-0.6-1.8-1.8-1.6-1.4-1.31.3-1.3-1.3-1.2-1.2-1.1-0.9-0.9-0.9-1.0-0.9-0.90.90.90.9-0.9-0.90.90.9-0.5-0.1
Cocaine response after cond. corrected4.65.69.9-1.9-3.1-3.1-3.0-2.9-2.82.7-2.7-2.6-2.6-2.5-2.4-2.0-2.2-2.2-2.3-2.1-2.12.12.12.1-2.1-2.12.12.11.0-0.9
Cocaine response after cond. not corrected5.05.910.5-2.4-3.2-3.2-3.1-2.9-2.82.8-2.7-2.7-2.6-2.5-2.4-2.0-2.2-2.2-2.3-2.2-2.22.22.22.2-2.2-2.22.22.21.3-0.9
Cocaine response before conditioning0.50.60.8-0.60.80.80.90.90.9-0.80.90.80.80.80.80.70.70.70.70.70.7-0.7-0.7-0.70.70.7-0.7-0.70.30.5
Saline control response0.10.10.40.6-0.6-0.6-0.6-0.5-0.50.5-0.5-0.4-0.4-0.4-0.4-0.4-0.3-0.3-0.3-0.2-0.20.20.20.2-0.2-0.20.20.20.10.0
Bone: connectivity density0.50.72.50.80.30.3-0.2-0.4-0.50.4-0.5-0.5-0.6-0.7-0.8-0.9-0.9-0.9-0.8-0.9-0.90.90.90.9-0.9-0.90.90.91.5-1.6
Bone: cortical apparent density1.01.31.80.9-1.0-1.0-1.2-1.2-1.21.3-1.2-1.3-1.2-1.2-1.2-1.4-1.0-1.0-1.2-1.1-1.11.11.11.1-1.1-1.11.11.11.1-1.1
Bone: cortical area0.50.81.90.6-0.4-0.4-0.6-0.7-0.80.7-0.8-0.8-0.9-0.9-1.0-1.1-1.1-1.1-0.9-1.0-1.01.01.01.0-1.0-1.01.01.01.4-1.3
Bone: cortical porosity0.10.10.30.30.60.60.50.40.3-0.40.30.40.30.20.20.20.10.10.30.20.2-0.2-0.2-0.20.20.2-0.2-0.20.3-0.3
Bone: cortical porosity0.10.10.80.90.60.60.30.20.1-0.10.10.1-0.0-0.1-0.1-0.2-0.4-0.4-0.1-0.2-0.20.20.20.2-0.2-0.20.20.20.8-0.9
Bone: cortical thickness1.21.93.20.9-1.0-1.0-1.2-1.3-1.41.3-1.4-1.3-1.4-1.5-1.5-1.6-1.5-1.5-1.4-1.4-1.41.41.41.4-1.4-1.41.41.41.8-1.7
Bone: cortical thickness0.20.33.0-1.7-0.7-0.7-0.3-0.2-0.1-0.0-0.00.10.00.10.10.20.40.40.30.40.4-0.4-0.4-0.40.40.4-0.4-0.4-0.30.8
Bone: cortical tissue density0.70.91.30.9-0.8-0.8-1.0-1.0-1.01.1-1.0-1.1-1.0-1.0-1.0-1.2-0.8-0.8-1.0-0.9-0.90.90.90.9-0.9-0.90.90.90.9-0.9
Condit. Reinf. active minus inactive responses4.55.16.31.02.42.42.42.42.5-2.32.52.32.52.52.42.32.42.42.22.12.1-2.1-2.1-2.12.12.1-2.1-2.1-2.52.0
Condit. Reinf. active-inactive response ratio2.32.53.9-0.11.21.21.41.51.6-1.51.61.51.61.71.71.61.71.71.61.61.6-1.6-1.6-1.61.61.6-1.6-1.6-2.01.9
Condit. Reinf. active responses3.84.87.62.32.82.82.62.52.4-2.42.42.32.32.32.22.02.12.12.12.02.0-2.0-1.9-1.91.91.9-1.9-1.9-2.01.2
Condit. Reinf. inactive responses0.91.15.62.41.81.81.41.31.2-1.21.11.11.00.90.80.70.40.40.90.80.8-0.8-0.7-0.70.70.7-0.7-0.7-0.4-0.3
Incentive salience index mean2.32.95.21.82.32.32.12.02.0-1.82.01.81.91.91.81.61.61.61.51.41.4-1.4-1.4-1.41.41.4-1.4-1.4-1.51.0
Condit. Reinf. lever presses0.40.56.22.51.21.20.70.50.4-0.30.30.20.20.1-0.0-0.3-0.3-0.3-0.1-0.2-0.20.20.20.2-0.2-0.20.20.20.9-1.2
Condit. Reinf. active minus inactive responses2.12.84.0-0.90.70.71.21.41.5-1.61.51.61.61.61.71.51.91.91.81.91.9-1.9-1.9-1.91.91.9-1.9-1.9-1.32.0
Condit. Reinf. active-inactive response ratio0.30.31.6-1.3-0.8-0.8-0.3-0.1-0.0-0.10.00.20.10.10.20.00.50.50.50.60.6-0.6-0.6-0.60.60.6-0.6-0.6-0.20.8
Condit. Reinf. active responses2.02.83.6-0.10.90.91.41.51.6-1.61.61.71.61.71.71.51.91.91.81.91.9-1.9-1.9-1.91.91.9-1.9-1.9-1.41.8
Condit. Reinf. inactive responses1.01.31.80.70.90.91.11.11.2-1.11.21.11.21.21.21.31.21.21.11.21.2-1.2-1.2-1.21.21.2-1.2-1.2-1.31.2
Condit. Reinf. lever presses1.82.53.2-0.11.01.01.31.41.5-1.61.51.61.61.61.61.51.71.71.71.81.8-1.8-1.8-1.81.81.8-1.8-1.8-1.51.8
Condit. Reinf. lever reinforcers received1.52.13.2-0.50.40.41.01.21.3-1.31.31.41.31.41.41.31.71.71.61.71.7-1.7-1.7-1.71.71.7-1.7-1.7-1.21.8
Conditioned reinforcement - actives0.91.69.1-3.00.60.60.91.01.1-1.01.11.01.21.21.21.41.31.31.11.11.1-1.1-1.1-1.11.11.1-1.1-1.1-1.11.6
Conditioned reinforcement - inactives0.10.23.3-1.8-0.3-0.3-0.3-0.2-0.20.3-0.1-0.3-0.1-0.1-0.10.00.10.1-0.2-0.2-0.20.20.20.2-0.2-0.20.20.20.00.3
Conditioned locomotion6.48.49.80.23.13.13.13.13.1-3.13.13.13.13.13.12.93.03.02.92.92.9-2.9-2.9-2.92.92.9-2.9-2.9-2.42.4
Patch foraging indifference point 0 sec0.20.30.60.1-0.4-0.4-0.5-0.5-0.60.5-0.6-0.5-0.6-0.6-0.6-0.7-0.7-0.7-0.5-0.5-0.50.50.50.5-0.5-0.50.50.50.8-0.8
Patch foraging indifference point AUC0.81.11.4-0.40.80.80.91.01.0-1.11.01.11.01.01.00.91.01.01.21.21.2-1.2-1.2-1.21.21.2-1.2-1.2-0.61.0
Delay disc. indifference point, 0s delay8.49.213.40.6-1.9-1.9-2.5-2.7-2.82.9-2.9-3.0-3.0-3.1-3.2-3.3-3.3-3.3-3.2-3.3-3.33.33.33.3-3.3-3.33.33.33.6-3.7
Delay disc. indifference point, 16s delay0.20.20.70.8-0.5-0.5-0.4-0.4-0.40.4-0.4-0.4-0.4-0.4-0.4-0.4-0.3-0.3-0.4-0.3-0.30.30.40.4-0.4-0.40.40.40.1-0.3
Delay disc. indifference point, 2s delay6.47.18.20.6-2.1-2.1-2.5-2.6-2.72.7-2.7-2.7-2.7-2.8-2.8-2.7-2.8-2.8-2.8-2.8-2.82.82.92.9-2.9-2.92.92.92.6-2.7
Delay disc. indifference point, 24s delay0.60.61.5-0.3-1.2-1.2-1.1-1.0-1.00.9-1.0-0.8-1.0-0.9-0.9-0.9-0.8-0.8-0.7-0.5-0.50.50.60.6-0.6-0.60.60.60.3-0.4
Delay disc. indifference point, 4s delay1.21.31.80.2-0.9-0.9-1.0-1.1-1.11.1-1.1-1.1-1.1-1.1-1.1-1.1-1.1-1.1-1.3-1.2-1.21.21.31.3-1.3-1.31.31.31.0-1.1
Delay disc. indifference point, 8s delay1.21.43.8-2.0-1.5-1.5-1.4-1.4-1.41.2-1.3-1.1-1.3-1.3-1.2-0.9-1.2-1.2-1.0-0.9-0.90.91.01.0-1.0-1.01.01.00.3-0.6
Indifference point function ln k0.10.20.4-0.5-0.7-0.7-0.6-0.5-0.50.6-0.5-0.6-0.5-0.4-0.4-0.3-0.3-0.3-0.5-0.5-0.50.50.50.5-0.5-0.50.50.50.1-0.0
Indifference point function log k0.10.20.4-0.5-0.7-0.7-0.6-0.5-0.50.6-0.5-0.6-0.5-0.4-0.4-0.3-0.3-0.3-0.5-0.5-0.50.50.50.5-0.5-0.50.50.50.1-0.0
Patch foraging total patch changes 0 sec0.10.20.4-0.1-0.3-0.3-0.4-0.4-0.50.4-0.5-0.4-0.5-0.5-0.5-0.5-0.6-0.6-0.4-0.5-0.50.50.50.5-0.5-0.50.50.50.6-0.6
Patch foraging total patch changes 12 sec0.30.41.5-1.2-0.8-0.8-0.8-0.8-0.80.6-0.8-0.6-0.8-0.7-0.7-0.6-0.7-0.7-0.5-0.4-0.40.40.40.4-0.4-0.40.40.40.6-0.4
Patch foraging total patch changes 18 sec0.71.11.50.21.21.21.11.11.1-1.21.11.21.11.11.10.90.90.91.21.11.1-1.1-1.1-1.11.11.1-1.1-1.1-0.60.7
Patch foraging total patch changes 24 sec0.10.10.60.80.40.40.30.30.3-0.30.20.30.20.20.20.00.10.10.30.30.3-0.3-0.3-0.30.30.3-0.3-0.30.4-0.1
Patch foraging total patch changes 6 sec0.10.20.30.10.50.50.50.50.5-0.60.50.60.40.40.40.30.30.30.50.50.5-0.5-0.5-0.50.50.5-0.5-0.50.00.0
Patch foraging time to switch 0 sec1.02.15.11.8-0.0-0.0-0.6-0.8-1.01.0-1.1-1.1-1.2-1.3-1.4-1.3-1.7-1.7-1.5-1.7-1.71.71.71.7-1.7-1.71.71.71.8-2.3
Patch foraging water rate 0 sec0.30.68.7-3.0-1.2-1.2-0.6-0.4-0.30.2-0.2-0.1-0.10.00.10.50.30.30.20.40.4-0.4-0.4-0.40.40.4-0.4-0.4-1.21.4
Patch foraging water rate 12 sec0.81.76.9-2.6-2.3-2.3-1.8-1.7-1.51.6-1.4-1.4-1.3-1.2-1.1-1.0-0.8-0.8-1.0-0.8-0.80.80.80.8-0.8-0.80.80.80.10.2
Patch foraging water rate 18 sec0.81.211.7-3.4-1.4-1.4-0.6-0.4-0.10.1-0.00.10.20.30.50.90.90.90.60.80.8-0.8-0.8-0.80.80.8-0.8-0.8-1.92.2
Patch foraging water rate 24 sec0.81.212.6-3.6-2.0-2.0-1.4-1.2-1.00.9-0.9-0.8-0.7-0.6-0.4-0.0-0.0-0.0-0.3-0.1-0.10.10.10.1-0.1-0.10.10.1-1.31.3
Patch foraging water rate 6 sec0.60.94.3-2.1-0.6-0.6-0.10.10.3-0.30.40.40.50.60.70.71.01.00.91.11.1-1.1-1.1-1.11.11.1-1.1-1.1-1.61.7
Seeking ratio, delayed vs. immediate footshock3.84.75.52.32.32.32.32.32.3-2.22.32.22.32.22.22.12.12.12.22.12.1-2.1-2.1-2.12.12.1-2.1-2.1-1.91.6
Distance traveled before self-admin0.30.43.01.7-0.3-0.3-0.4-0.4-0.50.5-0.5-0.6-0.5-0.5-0.5-0.6-0.6-0.6-0.6-0.6-0.60.60.60.6-0.6-0.60.60.60.2-0.7
Distance traveled after self-admin0.10.11.91.40.10.10.10.10.0-0.10.00.10.00.00.0-0.0-0.0-0.00.10.10.1-0.1-0.1-0.10.10.1-0.1-0.1-0.3-0.1
Extensor digitorum longus weight4.015.520.7-2.0-4.5-4.5-4.5-4.4-4.34.4-4.3-4.3-4.2-4.1-4.0-3.7-3.9-3.9-4.1-3.9-3.93.93.93.9-3.9-3.93.93.92.0-2.4
Bone: elastic displacement0.10.10.20.40.30.30.30.30.3-0.30.30.40.30.30.30.20.50.50.40.40.4-0.4-0.4-0.40.40.4-0.4-0.40.10.2
Bone: elastic work0.40.50.90.4-0.7-0.7-0.7-0.7-0.70.6-0.8-0.7-0.8-0.8-0.8-0.7-0.8-0.8-0.7-0.7-0.70.70.70.7-0.7-0.70.70.70.9-0.7
Bone: endosteal estimation0.20.40.60.3-0.5-0.5-0.5-0.5-0.50.7-0.5-0.7-0.5-0.5-0.5-0.5-0.7-0.7-0.7-0.7-0.70.70.80.8-0.8-0.80.80.80.4-0.5
Bone: endosteal perimeter0.20.41.1-0.11.01.01.00.90.8-0.80.80.70.80.80.70.60.60.60.60.50.5-0.5-0.5-0.50.50.5-0.5-0.5-0.20.3
Epididymis fat weight0.10.34.5-2.1-0.6-0.6-0.2-0.1-0.00.00.00.00.10.20.20.40.30.30.10.20.2-0.2-0.2-0.20.20.2-0.2-0.2-0.40.9
Delta time in closed arm before/after self-admin0.80.84.6-2.2-1.7-1.7-1.3-1.1-1.01.0-0.9-0.8-0.8-0.7-0.6-0.4-0.3-0.3-0.5-0.3-0.30.30.30.3-0.3-0.30.30.3-0.60.7
Delta time in open arm before/after self-admin0.50.50.60.2-0.6-0.6-0.7-0.7-0.70.7-0.7-0.7-0.8-0.8-0.8-0.7-0.7-0.7-0.7-0.7-0.70.70.70.7-0.7-0.70.70.70.4-0.6
Diff in mean of infusions in LGA sessions1.82.22.61.31.51.51.61.61.6-1.61.61.61.61.61.61.61.51.51.51.51.5-1.5-1.5-1.51.51.5-1.5-1.5-1.31.2
Delay discount exponential model param1.71.82.30.51.51.51.51.51.5-1.41.51.41.51.51.51.31.41.41.41.31.3-1.3-1.4-1.41.41.4-1.4-1.4-0.81.1
Extinction: sum of active levers before priming0.91.01.3-0.10.80.80.90.91.0-1.01.01.01.01.01.01.11.01.01.11.11.1-1.1-1.1-1.11.11.1-1.1-1.1-1.01.1
Active lever presses in extinction session 62.02.02.71.21.61.61.51.51.5-1.61.51.51.41.41.41.21.31.31.51.51.5-1.5-1.5-1.51.51.5-1.5-1.5-0.90.8
Bone: final force1.52.43.10.8-1.1-1.1-1.3-1.4-1.51.5-1.5-1.5-1.6-1.6-1.6-1.6-1.8-1.8-1.6-1.6-1.61.61.61.6-1.6-1.61.61.61.5-1.7
Bone: final moment1.21.92.50.9-1.0-1.0-1.2-1.3-1.31.3-1.4-1.3-1.4-1.4-1.5-1.5-1.6-1.6-1.4-1.5-1.51.51.51.5-1.5-1.51.51.51.3-1.5
Food consumed during 24 hour testing period0.50.71.1-0.2-1.1-1.1-1.0-1.0-1.00.9-0.9-0.8-0.9-0.9-0.9-0.6-0.8-0.8-0.8-0.8-0.80.80.80.8-0.8-0.80.80.80.0-0.4
Glucose2.74.35.8-0.9-2.4-2.4-2.4-2.3-2.32.2-2.3-2.2-2.2-2.2-2.2-2.2-2.1-2.1-2.0-1.9-1.91.91.91.9-1.9-1.91.91.92.0-1.6
Heart weight0.71.12.9-1.70.30.30.60.70.8-0.80.90.90.91.01.11.01.21.21.11.21.2-1.2-1.1-1.11.11.1-1.1-1.1-1.11.6
Delay discount hyperbolic model param3.03.33.90.21.81.81.92.02.0-1.92.01.92.02.02.01.81.91.91.91.81.8-1.8-1.9-1.91.91.9-1.9-1.9-1.41.6
Intermittent access intake day 1-15 change3.36.87.9-1.02.02.02.42.42.5-2.62.62.62.62.62.72.72.72.72.82.82.8-2.8-2.8-2.82.82.8-2.8-2.8-2.72.7
Intermittent access intake escalation2.96.07.5-0.71.91.92.22.32.4-2.42.42.52.42.52.52.52.52.52.62.62.6-2.6-2.6-2.62.62.6-2.6-2.6-2.72.5
Intermittent access intake escalation 24.75.36.30.01.91.92.12.22.2-2.32.32.42.32.32.32.32.42.42.52.52.5-2.5-2.5-2.52.52.5-2.5-2.5-2.42.3
Intermitt. access day 1 inactive lever presses0.10.55.9-2.4-0.4-0.4-0.1-0.00.1-0.10.20.20.20.30.40.60.50.50.40.50.5-0.5-0.5-0.50.50.5-0.5-0.5-1.11.2
Intermitt. access day 15 inactive lever presses0.20.40.7-0.40.80.80.80.80.8-0.70.80.70.70.70.70.70.70.70.60.50.5-0.5-0.5-0.50.50.5-0.5-0.5-0.80.5
Intermitt. access escalation Index0.81.22.21.4-0.5-0.5-0.7-0.8-0.91.0-0.9-1.0-1.0-1.0-1.1-1.2-1.2-1.2-1.1-1.2-1.21.21.21.2-1.2-1.21.21.21.1-1.5
Intermittent access day 1 total infusions0.20.46.8-2.6-0.0-0.00.20.20.3-0.20.30.30.40.40.50.60.50.50.30.30.3-0.3-0.3-0.30.30.3-0.3-0.3-0.40.9
Intermittent access day 15 total infusions2.43.64.3-1.71.51.51.81.81.9-1.91.91.91.92.02.02.02.02.01.91.91.9-1.9-1.9-1.91.91.9-1.9-1.9-2.02.1
Intermittent access terminal intake (last 3 days)1.82.33.5-1.91.31.31.51.51.5-1.61.51.61.61.61.61.71.61.61.51.51.5-1.5-1.5-1.51.51.5-1.5-1.5-1.41.6
Intermittent access total infusions1.01.25.6-2.40.80.80.91.01.0-1.01.01.01.11.11.11.21.11.11.01.01.0-1.0-1.0-1.01.01.0-1.0-1.0-1.01.2
Intermittent access day 1 locomotion1.62.04.2-2.00.80.81.11.21.3-1.21.41.31.41.51.51.71.61.61.31.41.4-1.4-1.4-1.41.41.4-1.4-1.4-1.61.9
Intermittent access day 15 total locomotion3.05.46.6-1.41.91.92.22.32.3-2.32.42.32.42.42.52.52.62.62.42.42.4-2.4-2.4-2.42.42.4-2.4-2.4-2.62.5
Intermittent access total locomotion2.32.73.7-1.01.31.31.51.61.7-1.61.71.61.71.81.81.91.81.81.61.61.6-1.6-1.6-1.61.61.6-1.6-1.6-1.91.9
Intermittent access standard deviation3.37.07.8-1.72.52.52.72.72.8-2.72.82.72.82.82.82.82.72.72.72.72.7-2.7-2.7-2.72.72.7-2.7-2.7-2.02.4
Left kidney weight0.10.32.6-1.6-0.8-0.8-0.3-0.3-0.10.3-0.1-0.2-0.00.00.10.50.10.10.00.10.1-0.1-0.1-0.10.10.1-0.1-0.1-1.30.9
Right kidney weight0.52.58.4-1.60.60.61.01.11.3-1.21.31.31.41.51.51.71.61.61.61.71.7-1.7-1.7-1.71.71.7-1.7-1.7-2.92.2
Cocaine induced anxiety1.01.44.12.01.91.91.61.51.4-1.41.31.31.31.21.10.90.90.91.00.90.9-0.9-0.9-0.90.90.9-0.9-0.9-0.10.0
Post-drug Anxiety1.51.69.33.11.91.91.61.51.4-1.41.41.31.31.21.10.90.90.91.00.90.9-0.9-0.9-0.90.90.9-0.9-0.9-0.10.0
Baseline Anxiety0.10.10.70.80.10.10.20.20.3-0.20.30.30.30.30.30.30.30.30.30.30.3-0.3-0.3-0.30.30.3-0.3-0.3-0.60.5
Tail length3.413.216.7-0.83.33.33.63.63.7-3.83.73.83.73.73.84.13.63.63.83.73.7-3.7-3.7-3.73.73.7-3.7-3.7-4.13.4
Length with tail2.08.610.6-0.62.62.62.92.93.0-3.13.03.13.03.03.03.32.92.93.13.03.0-3.0-3.0-3.03.03.0-3.0-3.0-3.22.7
Length without tail0.00.00.1-0.2-0.3-0.3-0.2-0.2-0.10.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.10.10.10.1-0.1-0.10.10.1-0.20.0
Times rat made contact with spout0.20.21.0-0.5-0.9-0.9-0.7-0.6-0.50.5-0.5-0.4-0.5-0.4-0.4-0.1-0.3-0.3-0.3-0.2-0.20.20.20.2-0.2-0.20.20.2-1.00.3
Lifetime Intake0.60.76.3-2.50.50.50.70.70.7-0.70.80.70.80.80.80.90.80.80.60.70.7-0.7-0.7-0.70.70.7-0.7-0.7-0.61.0
Liver weight, left0.91.52.3-0.5-1.5-1.5-1.4-1.3-1.31.4-1.3-1.4-1.3-1.2-1.2-1.3-1.1-1.1-1.2-1.1-1.11.11.11.1-1.1-1.11.11.11.0-0.7
Liver weight, right0.61.01.9-0.9-1.4-1.4-1.2-1.2-1.11.2-1.1-1.2-1.0-1.0-1.0-0.7-0.9-0.9-1.0-1.0-1.01.01.01.0-1.0-1.01.01.0-0.0-0.3
Locomotor activity2.74.27.12.12.72.72.42.32.2-2.42.22.32.12.01.91.71.81.82.12.02.0-2.0-2.0-2.02.02.0-2.0-2.0-1.00.7
Locomotor testing distance1.52.75.72.42.22.22.01.91.8-1.91.71.81.71.61.51.21.41.41.71.61.6-1.6-1.6-1.61.61.6-1.6-1.6-0.60.5
Locomotor testing rearing0.00.10.30.1-0.3-0.3-0.1-0.00.0-0.00.00.10.10.10.2-0.10.30.30.30.40.4-0.4-0.4-0.40.40.4-0.4-0.4-0.50.5
Locomotion in novel chamber0.91.11.50.10.70.70.90.91.0-1.01.01.01.01.01.01.01.11.11.21.21.2-1.2-1.2-1.21.21.2-1.2-1.2-1.01.1
Locomotion in novel chamber post-restriction1.11.82.60.71.01.01.31.31.4-1.31.41.41.41.41.51.61.41.41.41.41.4-1.4-1.4-1.41.41.4-1.4-1.4-1.61.6
Fecal boli incidents, locomotor time 11.11.62.20.6-1.2-1.2-1.4-1.4-1.41.2-1.4-1.3-1.4-1.4-1.4-1.1-1.5-1.5-1.3-1.3-1.31.31.31.3-1.3-1.31.31.30.9-1.2
Change in fecal boli incidents, locomotor task0.10.10.20.40.30.30.40.40.4-0.40.40.40.30.30.30.30.30.30.40.40.4-0.4-0.4-0.40.40.4-0.4-0.4-0.30.1
Time >=10cm from walls, locomotor time 10.70.72.41.6-0.3-0.3-0.6-0.7-0.80.6-0.8-0.7-0.9-0.9-1.0-1.1-1.1-1.1-0.6-0.7-0.70.70.60.6-0.6-0.60.60.61.0-1.5
Bouts of movement, locomotor time 10.40.51.7-0.50.40.40.60.60.6-0.60.70.60.70.70.70.90.60.60.70.70.7-0.7-0.7-0.70.70.7-0.7-0.7-1.30.8
Total resting periods, locomotor time 10.50.61.80.20.60.60.70.70.7-0.70.70.70.80.80.80.90.70.70.70.80.8-0.8-0.7-0.70.70.7-0.7-0.7-1.40.8
Rest time, locomotor task time 10.40.52.91.70.90.90.80.70.7-0.70.70.60.70.70.60.90.50.50.50.40.4-0.4-0.4-0.40.40.4-0.4-0.4-1.30.3
Distance moved, locomotor task time 10.81.23.70.4-0.5-0.5-0.8-0.9-1.00.9-1.0-0.9-1.1-1.1-1.2-1.4-1.2-1.2-1.0-1.0-1.01.01.01.0-1.0-1.01.01.01.9-1.6
Vertical activity count, locomotor time 10.20.52.0-1.4-1.2-1.2-1.0-0.9-0.80.7-0.8-0.6-0.8-0.7-0.7-0.8-0.5-0.5-0.4-0.3-0.30.30.30.3-0.3-0.30.30.30.6-0.2
Time >=10cm from walls, locomotor time 21.01.42.7-0.6-1.6-1.6-1.6-1.5-1.51.3-1.5-1.3-1.5-1.4-1.4-1.2-1.4-1.4-1.0-0.9-0.90.90.90.9-0.9-0.90.90.90.6-0.8
Bouts of movement, locomotor time 20.20.41.50.71.21.20.90.90.8-0.70.70.70.70.60.60.40.50.50.40.30.3-0.3-0.3-0.30.30.3-0.3-0.3-0.5-0.1
Total resting periods, locomotor time 20.20.31.50.61.21.20.90.80.7-0.70.70.60.60.60.50.40.40.40.40.20.2-0.2-0.3-0.30.30.3-0.3-0.3-0.4-0.2
Rest time, locomotor task time 20.60.71.61.01.31.31.11.01.0-1.00.90.90.90.90.80.80.70.70.80.80.8-0.8-0.7-0.70.70.7-0.7-0.7-0.80.3
Distance moved, locomotor task time 20.60.72.2-1.5-0.9-0.9-0.9-0.9-0.90.9-0.9-0.9-0.9-0.9-0.8-0.8-0.8-0.8-0.8-0.8-0.80.80.70.7-0.7-0.70.70.70.9-0.5
Vertical activity count, locomotor time 20.50.74.9-2.2-1.2-1.2-1.1-1.0-0.90.8-0.9-0.8-0.8-0.8-0.7-0.4-0.6-0.6-0.6-0.6-0.60.60.50.5-0.5-0.50.50.50.3-0.0
Light reinforcement 14.210.215.22.43.93.93.73.63.5-3.53.53.53.43.33.32.93.03.03.23.13.1-3.1-3.1-3.13.13.1-3.1-3.1-1.91.9
Light reinforcement 21.72.74.21.62.02.01.91.91.8-1.81.81.81.71.71.71.51.61.61.61.51.5-1.5-1.5-1.51.51.5-1.5-1.5-0.70.9
Bone: marrow area0.20.40.60.3-0.5-0.5-0.5-0.5-0.50.7-0.5-0.7-0.5-0.5-0.5-0.5-0.7-0.7-0.7-0.7-0.70.70.80.8-0.8-0.80.80.80.3-0.5
Bone: maximum diameter0.71.32.70.81.61.61.51.41.4-1.41.31.31.31.21.21.01.01.01.11.01.0-1.0-1.0-1.01.01.0-1.0-1.0-0.10.4
Bone: maximum force1.32.43.00.1-1.4-1.4-1.5-1.5-1.51.5-1.6-1.6-1.6-1.6-1.6-1.6-1.7-1.7-1.6-1.6-1.61.61.61.6-1.6-1.61.61.61.3-1.5
Bone: maximum moment1.12.02.50.2-1.3-1.3-1.3-1.4-1.41.4-1.4-1.4-1.4-1.5-1.5-1.5-1.6-1.6-1.5-1.5-1.51.51.51.5-1.5-1.51.51.51.2-1.3
Mean time between licks in bursts2.56.06.7-0.12.22.22.52.52.6-2.52.62.52.62.62.62.32.62.62.62.62.6-2.6-2.6-2.62.62.6-2.6-2.6-2.12.2
Mean num. licks in bursts0.10.22.61.60.10.1-0.1-0.1-0.10.1-0.1-0.1-0.2-0.2-0.2-0.1-0.2-0.2-0.3-0.3-0.30.30.30.3-0.3-0.30.30.3-0.5-0.4
Cd content in liver0.20.21.21.10.40.40.40.40.4-0.50.40.50.40.30.30.20.40.40.40.40.4-0.4-0.4-0.40.40.4-0.4-0.4-0.20.1
Co content in liver1.61.82.3-0.20.90.91.21.31.3-1.31.31.41.31.41.41.21.51.51.51.51.5-1.5-1.5-1.51.51.5-1.5-1.5-0.91.3
Cu content in liver0.20.20.80.80.90.90.70.60.5-0.60.50.50.40.40.30.30.20.20.30.20.2-0.2-0.2-0.20.20.2-0.2-0.2-0.1-0.4
Fe content in liver0.30.32.1-1.50.40.40.50.50.5-0.60.50.50.50.50.60.80.50.50.50.50.5-0.5-0.5-0.50.50.5-0.5-0.5-0.70.6
K content in liver0.10.11.11.00.50.50.40.30.2-0.20.20.10.10.10.0-0.2-0.1-0.1-0.0-0.1-0.10.10.10.1-0.1-0.10.10.10.6-0.6
Mg content in liver0.20.20.60.80.60.60.60.60.6-0.60.50.60.50.50.50.30.50.50.50.40.4-0.4-0.4-0.40.40.4-0.4-0.40.10.1
Mn content in liver1.21.43.91.52.02.01.71.51.4-1.51.41.31.31.21.11.10.80.81.00.80.8-0.8-0.8-0.80.80.8-0.8-0.8-0.5-0.1
Na content in liver1.01.12.60.6-0.1-0.1-0.5-0.7-0.80.8-0.8-0.9-0.9-1.0-1.0-1.1-1.2-1.2-1.1-1.2-1.21.21.21.2-1.2-1.21.21.21.6-1.6
Rb content in liver0.20.23.01.70.60.60.40.30.2-0.20.10.10.10.0-0.0-0.2-0.2-0.2-0.1-0.2-0.20.20.20.2-0.2-0.20.20.21.0-0.8
Se content in liver0.30.40.8-0.80.50.50.70.60.6-0.70.60.70.60.60.60.90.50.50.60.50.5-0.5-0.5-0.50.50.5-0.5-0.5-0.70.5
Sr content in liver0.00.00.1-0.3-0.3-0.3-0.2-0.2-0.10.1-0.1-0.1-0.1-0.1-0.00.00.00.0-0.00.00.0-0.0-0.0-0.00.00.0-0.0-0.0-0.30.2
Zn content in liver4.24.67.4-1.11.01.01.51.71.9-1.91.92.02.02.12.22.12.42.42.32.42.4-2.4-2.4-2.42.42.4-2.4-2.4-2.62.7
Bone: minimum diameter0.00.00.20.10.10.10.1-0.0-0.00.2-0.1-0.2-0.1-0.1-0.1-0.1-0.3-0.3-0.2-0.3-0.30.30.30.3-0.3-0.30.30.30.4-0.3
Time in familiar zone, hab. session 12.62.53.9-0.71.21.21.41.41.5-1.61.51.61.61.61.61.91.71.71.61.71.7-1.7-1.6-1.61.61.6-1.6-1.6-2.01.8
Time in novel zone, hab. session 11.51.54.10.5-0.8-0.8-0.9-1.0-1.11.2-1.1-1.2-1.1-1.2-1.2-1.5-1.3-1.3-1.3-1.3-1.31.31.31.3-1.3-1.31.31.32.0-1.5
Total zone transitions, hab. session 10.81.13.41.31.81.81.61.41.3-1.31.21.21.11.00.90.70.80.80.90.80.8-0.8-0.7-0.70.70.7-0.7-0.70.4-0.3
Total locomotion distance, hab. session 11.11.55.21.62.32.31.91.71.5-1.51.41.41.31.21.10.90.80.81.00.80.8-0.8-0.8-0.80.80.8-0.8-0.80.5-0.4
Locomotion velocity, hab. session 11.62.36.41.92.52.52.22.01.8-1.81.71.71.61.51.41.21.21.21.31.11.1-1.1-1.1-1.11.11.1-1.1-1.1-0.1-0.1
Time in familiar zone, hab. session 26.97.39.2-0.92.12.12.42.62.7-2.72.72.72.82.82.92.82.82.82.82.82.8-2.8-2.8-2.82.82.8-2.8-2.8-3.03.0
Time in novel zone, hab. session 25.35.36.41.1-1.8-1.8-2.1-2.2-2.32.3-2.3-2.3-2.4-2.4-2.5-2.4-2.4-2.4-2.4-2.4-2.42.42.42.4-2.4-2.42.42.42.1-2.5
Total zone transitions, hab. session 20.70.96.12.50.90.90.30.1-0.10.2-0.2-0.3-0.3-0.5-0.6-0.8-0.8-0.8-0.7-0.8-0.80.80.90.9-0.9-0.90.90.91.5-2.0
Total locomotion distance, hab. session 21.21.64.72.12.22.21.81.61.5-1.41.41.31.31.21.11.01.01.01.00.90.9-0.9-0.9-0.90.90.9-0.9-0.9-0.4-0.2
Locomotion velocity, hab. session 21.21.66.92.62.32.31.81.61.5-1.41.41.31.31.11.00.90.90.90.90.80.8-0.8-0.7-0.70.70.7-0.7-0.7-0.2-0.5
Novel to familiar place preference ratio4.85.27.20.7-1.6-1.6-1.9-2.0-2.22.2-2.2-2.3-2.3-2.3-2.4-2.5-2.5-2.5-2.4-2.4-2.42.42.42.4-2.4-2.42.42.42.7-2.7
Novelty place preference3.03.24.90.7-1.1-1.1-1.4-1.5-1.61.7-1.7-1.8-1.7-1.8-1.9-2.0-2.0-2.0-1.8-1.9-1.91.91.91.9-1.9-1.91.91.92.1-2.2
Time in novel zone, NPP test3.33.54.90.4-1.3-1.3-1.6-1.7-1.81.8-1.8-1.9-1.9-1.9-2.0-2.0-2.1-2.1-2.0-2.0-2.02.02.02.0-2.0-2.02.02.02.2-2.2
Total zone transitions, NPP test0.30.42.81.70.90.90.50.30.2-0.20.10.10.0-0.1-0.2-0.4-0.2-0.2-0.2-0.3-0.30.30.30.3-0.3-0.30.30.31.5-1.3
Total locomotion distance, NPP test0.20.32.91.70.90.90.50.30.2-0.10.10.00.0-0.1-0.1-0.4-0.3-0.3-0.2-0.4-0.40.40.40.4-0.4-0.40.40.41.0-1.2
Locomotion velocity, NPP test0.30.44.22.01.21.20.80.60.5-0.40.40.30.30.20.1-0.10.00.00.1-0.1-0.10.10.10.1-0.1-0.10.10.10.7-1.0
Intraocular pressure0.20.21.2-0.8-0.8-0.8-0.6-0.4-0.20.2-0.2-0.1-0.10.00.10.30.30.30.20.40.4-0.4-0.4-0.40.40.4-0.4-0.4-0.91.1
Delta distance traveled before/after self-admin0.50.50.70.10.50.50.60.70.7-0.80.70.80.70.70.70.80.70.70.80.90.9-0.9-0.9-0.90.90.9-0.9-0.9-0.60.7
Delta ambulatory time before/after self-admin0.40.50.60.00.70.70.70.70.7-0.80.70.80.70.70.70.80.60.60.80.70.7-0.7-0.7-0.70.70.7-0.7-0.7-0.50.5
Parametrial fat weight0.00.10.60.80.30.30.10.10.00.00.0-0.0-0.0-0.0-0.1-0.1-0.2-0.2-0.2-0.2-0.20.20.20.2-0.2-0.20.20.20.3-0.4
Pavlov. Cond. lever latency0.20.22.1-1.4-1.0-1.0-0.6-0.4-0.30.4-0.3-0.3-0.2-0.1-0.0-0.20.10.10.10.30.3-0.3-0.2-0.20.20.2-0.2-0.20.10.9
Pavlov. Cond. magazine entry latency3.54.56.30.52.42.42.42.32.3-2.32.32.22.32.32.32.52.12.12.12.02.0-2.0-2.0-2.02.02.0-2.0-2.0-2.51.8
Pavlov. Cond. change in total contacts0.10.10.50.10.60.60.50.40.4-0.40.40.40.40.40.30.50.20.20.20.20.2-0.2-0.2-0.20.20.2-0.2-0.2-0.70.1
Pavlov. Cond. index score0.60.82.10.91.41.41.21.11.0-1.01.01.01.00.90.91.20.70.70.70.60.6-0.6-0.6-0.60.60.6-0.6-0.6-1.20.3
Pavlov. Cond. latency score0.60.82.61.11.61.61.31.11.0-1.01.01.00.90.90.81.10.60.60.60.50.5-0.5-0.5-0.50.50.5-0.5-0.5-0.9-0.0
Pavlov. Cond. lever contacts0.20.21.91.40.90.90.50.40.3-0.30.20.20.10.10.00.2-0.1-0.1-0.1-0.3-0.30.30.30.3-0.3-0.30.30.3-0.0-0.8
Pavlov. Cond. magazine entry number1.11.43.6-0.4-1.3-1.3-1.3-1.3-1.31.2-1.3-1.2-1.3-1.3-1.3-1.5-1.1-1.1-1.1-1.0-1.01.01.01.0-1.0-1.01.01.01.9-1.0
Pavlov. Cond. intertrial magazine entries0.20.30.8-0.8-0.2-0.20.00.20.2-0.20.30.30.30.40.40.30.60.60.50.60.6-0.6-0.6-0.60.60.6-0.6-0.6-0.80.9
Pavlov. Cond. lever-magazine prob. diff.0.81.02.20.91.51.51.31.21.1-1.11.11.11.11.01.01.30.80.80.80.70.7-0.7-0.7-0.70.70.7-0.7-0.7-1.30.4
Pavlov. Cond. response bias1.11.43.10.51.41.41.31.31.3-1.21.31.21.21.21.21.51.11.11.11.01.0-1.0-1.0-1.01.01.0-1.0-1.0-1.80.9
Pavlov. Cond. lever latency0.70.91.4-0.7-0.5-0.5-0.7-0.8-0.81.0-0.8-1.0-0.8-0.9-0.9-0.8-0.9-0.9-1.1-1.1-1.11.11.11.1-1.1-1.11.11.11.2-1.0
Pavlov. Cond. magazine entry latency0.40.50.7-0.70.70.70.70.70.7-0.70.70.70.70.70.70.80.60.60.70.70.7-0.7-0.7-0.70.70.7-0.7-0.7-0.80.7
Pavlov. Cond. change in total contacts0.40.71.1-0.10.30.30.50.60.7-0.80.70.90.70.70.80.60.90.91.01.01.0-1.0-1.0-1.01.01.0-1.0-1.0-0.80.9
Pavlov. Cond. index score0.60.81.3-0.20.50.50.60.70.7-0.90.80.90.80.80.80.90.90.91.01.01.0-1.0-1.0-1.01.01.0-1.0-1.0-1.11.0
Pavlov. Cond. latency score0.60.71.0-0.10.60.60.70.80.8-0.90.80.90.80.80.80.80.80.81.01.01.0-1.0-1.0-1.01.01.0-1.0-1.0-1.00.9
Pavlov. Cond. lever contacts0.50.71.50.30.30.30.50.60.7-0.80.70.80.70.80.80.80.90.90.91.01.0-1.0-1.0-1.01.01.0-1.0-1.0-1.21.0
Pavlov. Cond. magazine entry number0.60.81.10.5-0.8-0.8-0.9-0.9-0.90.9-0.9-0.9-0.9-0.9-0.9-1.0-0.9-0.9-0.9-0.9-0.90.90.90.9-0.9-0.90.90.90.9-0.9
Pavlov. Cond. intertrial magazine entries0.30.41.5-0.2-1.2-1.2-0.8-0.8-0.70.8-0.7-0.7-0.6-0.6-0.6-0.6-0.4-0.4-0.6-0.5-0.50.50.50.5-0.5-0.50.50.50.3-0.0
Pavlov. Cond. lever-magazine prob. diff.0.60.81.0-0.20.60.60.70.80.8-0.90.80.90.80.90.90.90.90.91.01.01.0-1.0-1.0-1.01.01.0-1.0-1.0-1.00.9
Pavlov. Cond. response bias1.52.03.50.10.80.81.11.21.3-1.41.31.41.31.41.41.41.51.51.61.61.6-1.6-1.6-1.61.61.6-1.6-1.6-1.91.7
Time in closed arm before self-admin0.60.84.42.1-0.1-0.1-0.3-0.4-0.50.5-0.5-0.6-0.6-0.7-0.7-0.7-0.9-0.9-0.8-1.0-1.01.01.01.0-1.0-1.01.01.01.1-1.3
Time in closed arm after self-admin0.30.30.91.00.00.00.20.30.4-0.40.40.40.40.40.50.50.50.50.50.60.6-0.6-0.6-0.60.60.6-0.6-0.6-0.70.8
Time in open arm before self-admin0.10.10.8-0.90.30.30.30.30.3-0.20.30.20.30.30.30.20.20.20.20.20.2-0.2-0.2-0.20.20.2-0.2-0.20.20.1
Time in open arm after self-admin1.11.21.8-1.4-1.1-1.1-1.1-1.1-1.11.2-1.1-1.2-1.1-1.1-1.1-1.1-1.0-1.0-1.2-1.1-1.11.11.11.1-1.1-1.11.11.10.8-0.9
Bone: periosteal estimation0.30.61.20.8-0.2-0.2-0.4-0.5-0.60.7-0.6-0.7-0.6-0.7-0.7-0.8-0.9-0.9-0.8-0.9-0.90.90.90.9-0.9-0.90.90.91.1-1.1
Bone: periosteal perimeter0.10.10.50.50.70.70.60.50.4-0.40.40.40.30.30.20.10.00.00.20.10.1-0.1-0.1-0.10.10.1-0.1-0.10.3-0.3
Bone: post-yield work0.60.81.1-0.8-1.0-1.0-1.0-1.0-1.01.0-0.9-1.0-0.9-0.9-0.9-0.7-0.9-0.9-1.0-0.9-0.90.90.90.9-0.9-0.90.90.90.1-0.5
Progressive ratio test 1 active lever presses0.40.610.9-3.3-0.3-0.3-0.00.10.2-0.10.20.10.30.40.40.60.50.50.20.30.3-0.3-0.3-0.30.30.3-0.3-0.3-0.51.1
Progressive ratio test 1 breakpoint0.50.611.5-3.4-0.4-0.4-0.00.00.1-0.10.20.10.30.30.40.60.50.50.20.30.3-0.3-0.3-0.30.30.3-0.3-0.3-0.41.0
Progressive ratio test 1 inactive lever presses0.30.40.9-1.00.40.40.50.60.6-0.50.60.50.70.70.70.80.80.80.40.40.4-0.4-0.4-0.40.40.4-0.4-0.4-0.91.0
Progressive ratio test 2 active lever presses0.60.812.6-3.5-0.3-0.30.10.20.3-0.20.30.30.40.50.60.70.70.70.40.50.5-0.5-0.5-0.50.50.5-0.5-0.5-0.91.3
Progressive ratio test 2 breakpoint0.70.812.1-3.5-0.2-0.20.20.30.4-0.30.40.30.50.60.60.80.80.80.50.60.6-0.6-0.6-0.60.60.6-0.6-0.6-0.91.3
Progressive ratio test 2 inactive lever presses0.10.23.3-1.80.40.40.40.40.4-0.30.40.30.40.40.40.40.40.40.20.20.2-0.2-0.2-0.20.20.2-0.2-0.2-0.20.4
Incentive Sensitization - Responses0.20.36.8-2.6-0.7-0.7-0.4-0.4-0.30.3-0.2-0.3-0.2-0.1-0.10.10.10.1-0.00.00.0-0.0-0.0-0.00.00.0-0.0-0.0-0.60.6
Incentive Sensitization - Breakpoint0.20.35.0-2.2-0.5-0.5-0.3-0.2-0.10.2-0.1-0.1-0.00.00.10.20.20.20.10.20.2-0.2-0.2-0.20.20.2-0.2-0.2-0.70.6
Sum of active levers in priming session hrs 5-60.10.11.51.20.00.0-0.1-0.1-0.10.1-0.1-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.20.20.20.2-0.2-0.20.20.20.1-0.2
Progressive ratio0.20.22.9-1.7-0.5-0.5-0.5-0.5-0.50.4-0.5-0.4-0.5-0.4-0.4-0.3-0.4-0.4-0.3-0.3-0.30.30.30.3-0.3-0.30.30.30.1-0.1
Food seeking constrained by brief footshock0.30.31.00.21.01.00.90.80.8-0.60.70.60.70.70.60.80.50.50.40.30.3-0.3-0.3-0.30.30.3-0.3-0.3-0.30.2
Seeking ratio, punishment vs. effort0.30.43.01.70.90.90.90.80.8-0.60.70.60.70.70.60.60.50.50.40.30.3-0.3-0.3-0.30.30.3-0.3-0.3-0.20.1
Retroperitoneal fat weight0.31.42.6-1.5-1.6-1.6-1.4-1.4-1.31.4-1.3-1.3-1.2-1.1-1.1-0.9-1.1-1.1-1.2-1.1-1.11.11.11.1-1.1-1.11.11.10.1-0.3
Reaction time number correct0.40.83.2-1.3-1.8-1.8-1.2-1.1-0.91.0-0.9-0.9-0.8-0.7-0.6-0.3-0.3-0.3-0.6-0.5-0.50.50.50.5-0.5-0.50.50.5-1.30.6
Reaction time mean minus median0.30.71.1-1.10.60.60.70.70.8-0.80.80.80.80.80.90.90.90.90.90.90.9-0.9-0.9-0.90.90.9-0.9-0.9-0.51.0
Reaction time mean minus median AUC0.00.10.20.20.30.30.10.10.00.0-0.0-0.1-0.0-0.1-0.1-0.0-0.3-0.3-0.2-0.3-0.30.30.30.3-0.3-0.30.30.30.4-0.4
Reaction time num false alarms0.30.56.1-2.5-1.1-1.1-0.8-0.7-0.60.6-0.6-0.5-0.5-0.4-0.4-0.2-0.1-0.1-0.3-0.2-0.20.20.20.2-0.2-0.20.20.2-0.60.5
Reaction time num false alarms AUC0.30.57.3-2.7-1.2-1.2-0.9-0.8-0.60.6-0.6-0.6-0.5-0.4-0.4-0.2-0.1-0.1-0.3-0.2-0.20.20.20.2-0.2-0.20.20.2-0.70.6
Reaction time trials correct on left0.40.83.2-1.3-1.8-1.8-1.2-1.1-0.91.0-0.9-0.9-0.8-0.7-0.6-0.3-0.3-0.3-0.6-0.5-0.50.50.50.5-0.5-0.50.50.5-1.30.6
Reaction time trials on left0.40.83.2-1.2-1.8-1.8-1.2-1.1-0.91.0-0.9-1.0-0.8-0.7-0.6-0.4-0.3-0.3-0.7-0.5-0.50.50.50.5-0.5-0.50.50.5-1.20.5
Reaction time mean0.10.10.5-0.0-0.1-0.1-0.2-0.2-0.20.3-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.30.30.30.3-0.3-0.30.30.30.7-0.4
Reaction time mean AUC0.10.10.8-0.0-0.2-0.2-0.3-0.3-0.30.4-0.3-0.4-0.3-0.4-0.4-0.4-0.3-0.3-0.3-0.3-0.30.30.30.3-0.3-0.30.30.30.9-0.5
Median of all reaction times0.40.51.30.3-0.4-0.4-0.6-0.6-0.70.7-0.7-0.7-0.7-0.7-0.8-0.7-0.7-0.7-0.7-0.7-0.70.70.70.7-0.7-0.70.70.71.1-0.9
Reaction time omissions0.20.34.92.20.60.60.50.50.4-0.30.40.30.40.30.30.10.20.20.20.20.2-0.2-0.2-0.20.20.2-0.2-0.2-0.1-0.2
Reaction time false alarm rate0.10.11.9-1.4-0.2-0.2-0.3-0.3-0.30.2-0.3-0.2-0.3-0.3-0.3-0.2-0.2-0.2-0.2-0.2-0.20.20.20.2-0.2-0.20.20.20.3-0.1
Reaction time premature initiation rate1.01.41.9-0.80.70.70.91.01.1-1.01.11.11.11.21.21.21.21.21.31.41.4-1.4-1.4-1.41.41.4-1.4-1.4-0.91.4
Reaction time premature initiations0.71.23.3-1.4-0.2-0.20.30.50.7-0.60.70.70.80.91.01.11.21.21.11.21.2-1.2-1.2-1.21.21.2-1.2-1.2-1.81.8
Std. dev. reaction times0.10.10.6-0.80.20.20.30.30.3-0.30.30.30.30.30.30.40.30.30.40.40.4-0.4-0.4-0.40.40.4-0.4-0.40.20.4
Reaction time trials completed0.40.83.2-1.2-1.8-1.8-1.2-1.1-0.91.0-0.9-1.0-0.8-0.7-0.6-0.4-0.3-0.3-0.7-0.5-0.50.50.50.5-0.5-0.50.50.5-1.20.5
Reaction time trials AUC0.40.83.5-1.5-1.9-1.9-1.3-1.1-0.91.0-0.9-0.9-0.8-0.7-0.6-0.3-0.3-0.3-0.6-0.4-0.40.40.40.4-0.4-0.40.40.4-1.40.7
Run reversals in cocaine runway, females0.50.51.21.01.11.11.00.90.9-0.80.90.80.80.80.80.80.70.70.60.50.5-0.5-0.5-0.50.50.5-0.5-0.5-0.40.3
Run reversals in cocaine runway, males1.81.95.72.41.61.61.61.61.5-1.41.51.41.51.41.41.31.31.31.21.11.1-1.1-1.1-1.11.11.1-1.1-1.1-0.90.9
Latency to leave start box in cocaine runway0.40.43.61.90.80.80.70.70.6-0.70.50.60.50.40.4-0.10.30.30.50.40.4-0.4-0.4-0.40.40.4-0.4-0.40.8-0.4
Latency to leave start box in cocaine runway, F0.60.65.92.40.30.30.0-0.1-0.20.1-0.3-0.2-0.4-0.5-0.5-1.0-0.7-0.7-0.4-0.5-0.50.50.50.5-0.5-0.50.50.51.9-1.5
Latency to leave start box in cocaine runway, M2.01.92.3-0.41.01.01.21.31.3-1.31.31.41.41.41.41.41.51.51.51.51.5-1.5-1.5-1.51.51.5-1.5-1.5-1.31.5
Std. dev. time between licks in bursts0.50.70.9-0.00.70.70.90.90.9-0.80.90.80.90.90.90.70.80.80.80.80.8-0.8-0.8-0.80.80.8-0.8-0.8-0.80.6
Total sessions with >9 infusions0.20.32.3-1.50.20.20.30.40.4-0.30.40.30.50.50.60.70.60.60.30.30.3-0.3-0.3-0.30.30.3-0.3-0.3-0.60.9
Short access day 1 total inactive lever presses0.30.43.0-1.70.60.60.60.60.7-0.60.70.60.70.70.70.80.70.70.40.40.4-0.4-0.4-0.40.40.4-0.4-0.4-0.60.7
Short access day 10 total inactive lever presses0.00.11.2-1.1-0.3-0.3-0.3-0.2-0.20.0-0.2-0.0-0.1-0.1-0.10.0-0.0-0.00.10.10.1-0.1-0.1-0.10.10.1-0.1-0.1-0.70.3
Short access day 1 total infusions0.30.41.0-1.00.70.70.70.70.7-0.60.70.60.70.70.70.80.70.70.50.40.4-0.4-0.4-0.40.40.4-0.4-0.4-0.40.7
Short access day 10 total infusions0.30.47.9-2.8-0.1-0.10.10.20.2-0.10.30.10.30.40.40.50.50.50.10.20.2-0.2-0.2-0.20.20.2-0.2-0.2-0.30.9
Short access total infusions0.40.55.2-2.30.40.40.50.50.5-0.40.60.50.60.60.60.70.60.60.50.50.5-0.5-0.5-0.50.50.5-0.5-0.5-0.30.8
Short access day 1 locomotion1.11.42.0-0.31.11.11.21.31.3-1.21.31.11.31.41.41.41.41.41.11.01.0-1.0-1.0-1.01.01.0-1.0-1.0-1.11.4
Short access day 10 total locomotion4.07.410.4-2.61.81.82.42.52.6-2.52.72.62.82.82.93.03.03.02.72.82.8-2.8-2.8-2.82.82.8-2.8-2.8-2.63.2
Short access total locomotion1.92.33.4-0.91.21.21.41.51.6-1.51.61.51.61.71.71.81.71.71.51.51.5-1.5-1.5-1.51.51.5-1.5-1.5-1.41.8
One hour access (0.3 mA shock)0.20.35.8-2.4-0.3-0.3-0.2-0.1-0.10.3-0.1-0.3-0.1-0.00.00.10.10.1-0.3-0.3-0.30.30.30.3-0.3-0.30.30.30.20.3
Compulsive drug intake1.61.98.93.0-0.4-0.4-0.8-0.9-1.11.1-1.1-1.2-1.2-1.2-1.3-1.5-1.4-1.4-1.3-1.4-1.41.41.41.4-1.4-1.41.41.41.5-1.9
One hour access (shock baseline)0.81.213.7-3.70.20.20.60.70.7-0.60.80.60.90.91.01.11.11.10.70.70.7-0.7-0.7-0.70.70.7-0.7-0.7-0.81.5
Social response proportion0.80.91.60.51.31.31.21.11.1-1.11.01.01.01.00.90.70.90.91.00.90.9-0.9-0.9-0.90.90.9-0.9-0.9-0.50.3
Social responses6.58.311.00.23.33.33.23.23.1-3.23.13.13.03.02.92.62.82.83.02.92.9-2.9-2.9-2.92.92.9-2.9-2.9-1.82.0
Social time0.40.61.40.5-0.6-0.6-0.7-0.7-0.80.8-0.8-0.8-0.8-0.8-0.8-1.2-0.8-0.8-0.7-0.7-0.70.70.70.7-0.7-0.70.70.71.2-0.9
Soleus weight8.324.327.8-0.3-5.0-5.0-5.2-5.2-5.25.3-5.2-5.3-5.2-5.2-5.1-5.0-5.0-5.0-5.1-5.0-5.05.05.05.0-5.0-5.05.05.03.8-4.0
Bone: stiffness2.74.45.5-0.7-1.7-1.7-1.9-2.0-2.02.1-2.1-2.1-2.1-2.1-2.1-2.2-2.3-2.3-2.2-2.2-2.22.22.22.2-2.2-2.22.22.22.0-2.0
Tibialis anterior weight1.03.54.10.1-2.0-2.0-1.9-2.0-1.92.0-1.9-2.0-1.9-1.9-1.9-1.8-1.9-1.9-2.0-2.0-2.02.02.02.0-2.0-2.02.02.00.9-1.4
Time to tail flick, vehicle, before self-admin0.30.37.12.70.50.50.40.40.3-0.30.30.30.30.30.20.20.20.20.20.10.1-0.1-0.1-0.10.10.1-0.1-0.1-0.2-0.1
Time to tail flick, vehicle, after self-admin0.70.95.3-2.30.00.00.30.40.5-0.60.60.70.70.70.80.90.90.90.91.01.0-1.0-1.0-1.01.01.0-1.0-1.0-1.01.5
Time to tail flick, test, before self-admin0.20.20.70.60.90.90.70.60.6-0.50.60.40.50.50.40.30.40.40.30.30.3-0.3-0.3-0.30.30.3-0.3-0.30.4-0.1
Time to tail flick, test, after self-admin0.10.20.80.90.30.30.40.40.4-0.40.40.40.40.40.40.50.40.40.30.30.3-0.3-0.3-0.30.30.3-0.3-0.3-0.30.4
Delta time to tail flick, vehicle, before/after SA0.60.510.2-3.2-0.9-0.9-0.7-0.6-0.40.4-0.4-0.3-0.3-0.2-0.2-0.0-0.0-0.0-0.10.10.1-0.1-0.1-0.10.10.1-0.1-0.1-0.40.7
Delta time to tail flick, test, before/after SA0.20.20.9-0.9-0.5-0.5-0.2-0.10.0-0.10.00.10.10.20.20.40.30.30.20.30.3-0.3-0.3-0.30.30.3-0.3-0.3-1.00.8
Tibia length0.82.32.8-0.91.31.31.41.51.5-1.51.51.61.51.51.51.31.71.71.61.61.6-1.6-1.6-1.61.61.6-1.6-1.6-1.41.4
Ambulatory time before self-admin0.30.42.41.5-0.3-0.3-0.4-0.5-0.50.6-0.5-0.6-0.5-0.5-0.6-0.6-0.6-0.6-0.6-0.6-0.60.60.60.6-0.6-0.60.60.60.2-0.6
Ambulatory time after self-admin0.10.11.91.40.10.10.0-0.0-0.00.0-0.0-0.0-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.10.10.10.1-0.1-0.10.10.1-0.1-0.3
Bone: tissue strength2.02.02.80.7-1.1-1.1-1.4-1.4-1.51.4-1.5-1.4-1.5-1.5-1.5-1.7-1.5-1.5-1.5-1.5-1.51.51.51.5-1.5-1.51.51.51.2-1.5
Total heroin consumption1.51.82.61.61.61.61.51.51.5-1.41.41.41.41.41.41.21.31.31.31.21.2-1.2-1.2-1.21.21.2-1.2-1.2-0.70.8
Bone: trabecular number0.30.52.20.41.51.51.11.00.9-0.90.80.80.70.70.60.60.50.50.60.40.4-0.4-0.4-0.40.40.4-0.4-0.40.6-0.3
Bone: trabecular spacing0.50.73.5-1.7-1.9-1.9-1.2-1.0-0.90.8-0.8-0.7-0.7-0.6-0.5-0.2-0.2-0.2-0.3-0.2-0.20.20.20.2-0.2-0.20.20.2-0.80.9
Bone: trabecular thickness0.81.09.73.11.21.20.40.1-0.10.0-0.2-0.1-0.4-0.5-0.6-0.9-0.8-0.8-0.5-0.7-0.70.70.70.7-0.7-0.70.70.71.5-2.2
Bone: trabecular tissue density1.21.72.3-0.3-1.5-1.5-1.5-1.4-1.41.5-1.4-1.4-1.4-1.4-1.4-1.3-1.3-1.3-1.4-1.3-1.31.31.31.3-1.3-1.31.31.30.3-0.9
Water consumed over 24 hours0.71.01.41.2-0.8-0.8-0.9-0.9-1.00.9-1.0-0.9-1.0-1.0-1.1-0.9-1.1-1.1-1.0-1.1-1.11.11.11.1-1.1-1.11.11.10.6-1.1
Number of responses in last shaping day1.61.73.1-0.61.01.01.21.21.3-1.21.31.31.41.41.41.61.51.51.31.31.3-1.3-1.3-1.31.31.3-1.3-1.3-1.81.7