Hub : Genes

Arhgap28

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc alternative polyA XM_006245626.5 0.04 0.03 7.0e-05 0.03 0.02 0.03 0.01 9.4e-05 2.6e-04 4.9e-05 2.8e-02
2 NAcc alternative polyA XM_039083430.2 0.04 0.02 2.1e-04 0.02 0.02 0.03 0 1.2e-04 4.1e-04 6.1e-05 1.1e-01
3 IC gene expression Arhgap28 0.07 0.05 4.6e-03 0.05 0.05 0.06 0.05 3.9e-03 3.5e-03 1.5e-03 3.2e-03
4 NAcc gene expression Arhgap28 0.09 0.05 1.4e-14 0.09 0.06 0.09 0.05 2.6e-13 3.6e-09 7.0e-14 9.2e-08
5 Brain alternative polyA NM_001191815.1 0.03 0.02 9.7e-03 0.02 0.02 0.02 0.02 3.1e-03 7.7e-03 6.6e-03 7.2e-03
6 Brain alternative polyA XM_039083430.2 0.03 0.02 7.4e-03 0.02 0.02 0.02 0.02 2.8e-03 6.2e-03 4.9e-03 7.7e-03
7 Brain alternative polyA NM_001191815.1 0.03 0.02 9.9e-03 0.02 0.02 0.02 0.02 3.1e-03 7.6e-03 6.4e-03 7.8e-03
8 Brain alternative polyA XM_006245626.5 0.03 0.02 7.9e-03 0.02 0.02 0.02 0.02 3.2e-03 6.6e-03 5.4e-03 8.4e-03
9 Brain isoform ratio XM_039083430.2 0.06 0.04 1.2e-04 0.05 0.03 0.02 0.03 4.1e-05 6.9e-04 3.8e-03 8.8e-04
10 Brain gene expression Arhgap28 0.22 0.09 0.0e+00 0.23 0.22 0.23 0.23 2.3e-21 1.2e-20 3.8e-21 7.2e-21
11 pVTA gene expression Arhgap28 0.37 0.06 0.0e+00 0.52 0.25 0.52 0.25 5.0e-49 3.1e-20 1.2e-47 6.7e-20
12 pVTA isoform ratio XM_039083430.2 0.08 0.06 1.0e-05 0.07 0.06 0.07 0.07 5.5e-06 1.3e-05 3.3e-06 2.6e-06
13 BLA gene expression Arhgap28 0.35 0.14 3.9e-12 0.24 0.21 0.19 0.23 1.0e-12 2.2e-11 2.0e-10 3.2e-12
14 PL gene expression Arhgap28 0.08 0.04 2.8e-08 0.09 0.03 0.07 0.03 2.5e-10 1.2e-04 1.4e-08 2.8e-04
15 LHb gene expression Arhgap28 0.61 0.14 1.2e-10 0.31 0.32 0.29 0.3 4.3e-08 2.4e-08 1.2e-07 6.0e-08
16 RMTg mRNA stability Arhgap28 0.15 0.1 2.5e-03 0.05 0.03 0.04 0.04 1.9e-02 6.8e-02 3.0e-02 3.9e-02
17 pVTA intron excision ratio chr9_115283943_115289846 0.06 0.05 1.6e-05 0.04 0.05 0.05 0.04 2.1e-04 5.4e-05 7.2e-05 5.7e-04
18 OFC alternative TSS XM_006245626.5 0.27 0.15 4.4e-03 0.15 0.14 0.12 0.14 1.7e-04 3.8e-04 9.2e-04 2.6e-04
19 Adipose mRNA stability Arhgap28 0.02 0.02 4.4e-03 0.02 0.01 0.01 0.01 4.6e-03 8.7e-03 5.5e-02 3.1e-02
20 Liver alternative polyA XM_039083430.2 0.02 0.01 7.6e-03 0.01 0.01 0.01 0.01 7.7e-03 1.4e-02 1.9e-02 1.4e-02
21 Liver alternative polyA XM_006245626.5 0.02 0.01 8.2e-03 0.01 0.01 0.01 0.01 8.4e-03 1.6e-02 2.1e-02 1.5e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density6.110.512.9-3.6-3.6-3.5-3.43.3-3.33.3-3.3-3.3-3.3-3.2-3.3-3.2-3.2-3.5-3.23.42.52.7-2.8-2.8
Area under the delay curve1.31.52.21.51.51.31.3-1.21.2-1.21.21.21.31.31.21.31.31.41.1-1.2-0.5-0.80.90.9
BMI with tail3.010.212.33.43.33.23.5-3.43.4-3.43.43.43.43.43.53.23.22.93.3-3.2-3.1-2.42.22.2
BMI without tail1.23.76.21.41.31.52.3-2.12.1-2.12.12.12.02.11.72.02.01.61.9-2.2-2.5-2.21.51.5
Body weight4.519.824.65.04.94.74.8-4.84.8-4.84.84.84.74.74.94.54.54.14.4-4.4-4.1-3.13.03.0
Weight adjusted by age0.10.10.4-0.2-0.1-0.6-0.20.5-0.50.5-0.5-0.5-0.5-0.5-0.4-0.2-0.2-0.4-0.20.3-0.3-0.20.10.1
Bone surface4.37.810.0-3.0-3.0-2.9-3.02.9-2.92.9-2.9-2.9-2.8-2.8-2.5-2.8-2.8-3.2-2.83.02.02.5-2.5-2.5
Bone volume5.910.613.0-3.6-3.6-3.6-3.43.5-3.53.5-3.5-3.5-3.4-3.4-3.1-3.3-3.3-3.5-3.43.32.12.4-2.5-2.5
Breakpoint value in progressive ratio session0.60.71.60.90.90.50.8-0.60.6-0.60.60.60.60.61.10.80.80.70.6-0.8-1.1-1.01.31.3
Number of licking bursts0.20.31.20.40.40.50.5-0.50.5-0.50.50.50.50.30.90.30.30.10.3-0.5-1.1-0.50.50.5
Context. condit. distance diff. score0.20.31.4-0.3-0.4-0.40.10.1-0.10.1-0.1-0.1-0.2-0.1-0.0-0.0-0.00.2-0.0-0.6-0.9-1.21.21.2
Locomotion velocity, session 10.60.61.2-0.3-0.2-0.7-0.81.1-1.11.1-1.1-1.1-1.0-1.0-0.1-0.8-0.8-0.9-0.80.7-0.20.5-0.5-0.5
Locomotion distance, session 10.50.71.91.31.41.10.7-0.80.8-0.80.80.80.70.81.11.01.00.61.0-0.4-0.30.3-0.2-0.2
Locomotion velocity, session 20.20.20.90.30.30.2-0.1-0.10.1-0.10.10.10.10.1-0.20.10.1-0.00.10.40.90.9-0.9-0.9
Locomotion distance, session 20.40.61.00.91.00.90.7-0.90.9-0.90.90.90.80.90.41.01.00.71.0-0.30.50.5-0.4-0.4
Locomotion velocity, session 30.80.91.7-0.4-0.3-0.6-0.81.3-1.31.3-1.3-1.3-1.3-1.10.6-1.0-1.0-1.2-1.00.6-1.20.2-0.4-0.4
Locomotion distance, session 31.11.23.61.31.31.11.0-0.70.7-0.70.70.70.70.81.80.80.80.90.8-1.2-1.9-1.21.21.2
Stereotopy head waving bouts, day 33.33.95.5-2.3-2.3-2.3-2.12.2-2.22.2-2.2-2.2-2.2-2.1-1.9-2.1-2.1-2.0-2.11.70.90.9-1.0-1.0
Stereotopy head waving duration, day 37.58.912.1-3.2-3.2-3.2-3.23.5-3.53.5-3.5-3.5-3.5-3.4-2.4-3.4-3.4-3.2-3.42.60.91.3-1.3-1.3
Locomotion velocity, session 70.50.60.90.70.70.80.8-0.80.8-0.80.80.80.80.80.70.80.81.00.8-0.9-0.4-0.70.70.7
Locomotion distance, session 72.02.63.81.41.31.51.7-1.61.6-1.61.61.61.61.71.21.61.61.91.6-1.9-0.9-1.71.81.8
Stereotopy head waving bouts, day 70.10.10.1-0.3-0.2-0.2-0.30.3-0.30.3-0.3-0.3-0.3-0.3-0.1-0.3-0.3-0.3-0.30.30.10.2-0.3-0.3
Stereotopy head waving duration, day 70.60.71.1-0.6-0.5-0.6-0.91.0-1.01.0-1.0-1.0-1.0-1.0-0.1-0.9-0.9-1.1-0.90.8-0.10.7-0.8-0.8
Locomotion velocity, session 80.50.71.1-0.8-0.8-0.9-0.80.8-0.80.8-0.8-0.8-0.7-0.7-1.0-0.6-0.6-0.7-0.60.80.80.9-1.1-1.1
Locomotion distance, session 80.20.21.00.10.00.10.4-0.10.1-0.10.10.10.10.20.50.30.30.30.3-0.7-1.0-0.90.90.9
Degree of sensitization distance0.30.41.8-0.1-0.20.20.3-0.70.7-0.70.70.70.70.6-0.80.60.60.80.6-0.41.3-0.10.10.1
Degree of sensitization stereotypy0.30.30.60.70.70.60.5-0.50.5-0.50.50.50.50.50.80.50.50.40.5-0.5-0.7-0.40.20.2
Conditioned locomotion1.92.23.51.51.51.21.5-1.41.4-1.41.41.41.41.41.11.41.41.91.3-1.8-1.1-1.91.81.8
Cocaine response after cond. corrected3.23.95.12.12.02.22.1-2.32.3-2.32.32.32.32.21.62.12.12.02.1-1.8-0.9-1.11.31.3
Cocaine response after cond. not corrected5.97.09.12.82.72.82.8-3.03.0-3.03.03.03.02.82.22.82.82.82.7-2.5-1.2-1.61.91.9
Cocaine response before conditioning1.01.12.60.80.70.71.0-1.01.0-1.01.01.01.00.90.80.90.91.20.9-1.3-0.9-1.51.61.6
Saline control response0.20.30.7-0.5-0.5-0.4-0.60.6-0.60.6-0.6-0.6-0.7-0.8-0.2-0.7-0.7-0.5-0.70.40.20.20.20.2
Bone: connectivity density4.46.99.3-2.7-2.7-2.5-2.72.5-2.52.5-2.5-2.5-2.5-2.4-2.6-2.3-2.3-2.8-2.33.02.62.9-3.1-3.1
Bone: cortical apparent density3.04.05.52.32.32.12.2-2.12.1-2.12.12.12.22.11.82.12.12.32.2-2.0-1.1-1.51.51.5
Bone: cortical area0.40.63.30.30.40.20.4-0.00.0-0.00.00.0-0.0-0.01.0-0.0-0.00.3-0.0-0.9-1.8-1.51.61.6
Bone: cortical porosity0.20.20.7-0.8-0.9-0.7-0.40.4-0.40.4-0.4-0.4-0.4-0.4-0.6-0.4-0.4-0.3-0.40.20.2-0.00.00.0
Bone: cortical porosity0.00.00.2-0.4-0.4-0.3-0.00.1-0.10.1-0.1-0.1-0.1-0.1-0.2-0.1-0.1-0.0-0.1-0.1-0.0-0.20.30.3
Bone: cortical thickness1.22.06.51.11.10.91.2-0.80.8-0.80.80.80.70.71.70.70.71.20.7-1.8-2.6-2.42.42.4
Bone: cortical thickness1.92.35.91.00.91.01.5-1.11.1-1.11.11.11.11.01.51.01.01.31.0-1.9-2.3-2.42.42.4
Bone: cortical tissue density3.14.25.62.42.42.22.2-2.22.2-2.22.22.22.22.21.72.22.22.32.2-2.0-1.0-1.41.41.4
Condit. Reinf. active minus inactive responses2.32.64.01.61.61.61.8-1.51.5-1.51.51.51.51.52.01.51.51.51.5-1.9-2.0-1.81.51.5
Condit. Reinf. active-inactive response ratio2.42.63.21.61.51.71.8-1.71.7-1.71.71.71.71.71.51.71.71.71.7-1.7-1.2-1.31.11.1
Condit. Reinf. active responses1.41.82.31.31.31.31.5-1.31.3-1.31.31.31.31.41.41.41.41.41.4-1.5-1.4-1.41.11.1
Condit. Reinf. inactive responses0.30.40.6-0.6-0.6-0.8-0.60.6-0.60.6-0.6-0.6-0.6-0.5-0.8-0.5-0.5-0.5-0.50.60.70.5-0.6-0.6
Incentive salience index mean1.82.23.11.61.61.51.7-1.41.4-1.41.41.41.51.51.81.51.51.41.5-1.6-1.6-1.41.01.0
Condit. Reinf. lever presses0.10.10.20.40.40.30.3-0.30.3-0.30.30.30.30.40.20.40.40.20.4-0.1-0.00.1-0.3-0.3
Condit. Reinf. active minus inactive responses2.43.14.81.51.51.61.9-1.71.7-1.71.71.71.61.71.61.71.72.11.7-2.1-1.4-2.12.22.2
Condit. Reinf. active-inactive response ratio3.33.94.92.01.91.92.1-2.22.2-2.22.22.22.22.21.62.22.22.12.2-1.9-1.0-1.31.21.2
Condit. Reinf. active responses1.52.18.00.60.60.71.3-0.90.9-0.90.90.90.80.81.01.01.01.61.0-2.0-1.7-2.62.82.8
Condit. Reinf. inactive responses0.81.13.3-1.1-1.1-1.1-0.51.0-1.01.0-1.0-1.0-1.0-1.0-0.6-0.8-0.8-0.2-0.8-0.4-0.9-1.51.81.8
Condit. Reinf. lever presses0.70.94.00.40.30.50.8-0.50.5-0.50.50.50.40.40.90.50.50.80.5-1.3-1.4-1.72.02.0
Condit. Reinf. lever reinforcers received1.52.18.00.70.60.71.3-0.90.9-0.90.90.90.80.81.01.01.01.61.0-2.0-1.6-2.62.82.8
Conditioned reinforcement - actives0.10.10.6-0.1-0.1-0.0-0.00.2-0.20.2-0.2-0.2-0.2-0.20.2-0.0-0.00.1-0.0-0.3-0.5-0.50.70.7
Conditioned reinforcement - inactives2.73.95.41.91.81.92.2-2.02.0-2.02.02.02.02.01.82.02.02.12.1-2.3-1.9-2.01.91.9
Conditioned locomotion1.41.82.3-1.1-1.1-1.5-1.51.5-1.51.5-1.5-1.5-1.5-1.5-1.4-1.4-1.4-1.3-1.41.20.80.9-1.2-1.2
Patch foraging indifference point 0 sec0.10.20.5-0.4-0.4-0.2-0.50.4-0.40.4-0.4-0.4-0.4-0.5-0.2-0.5-0.5-0.4-0.60.60.70.6-0.6-0.6
Patch foraging indifference point AUC0.20.31.90.40.40.50.2-0.30.3-0.30.30.30.30.40.10.40.4-0.00.40.50.71.0-1.4-1.4
Delay disc. indifference point, 0s delay0.00.00.3-0.0-0.0-0.1-0.1-0.00.0-0.00.00.0-0.0-0.0-0.1-0.2-0.2-0.6-0.30.20.20.3-0.3-0.3
Delay disc. indifference point, 16s delay0.80.81.31.11.11.00.9-1.01.0-1.01.01.01.01.00.81.01.01.10.9-0.9-0.3-0.50.40.4
Delay disc. indifference point, 2s delay0.70.71.41.11.10.90.8-1.01.0-1.01.01.01.01.00.61.21.20.71.0-0.50.30.2-0.1-0.1
Delay disc. indifference point, 24s delay1.11.32.4-1.0-1.0-1.3-1.21.0-1.01.0-1.0-1.0-1.0-1.0-1.5-1.0-1.0-0.9-1.21.21.51.2-1.1-1.1
Delay disc. indifference point, 4s delay1.92.02.61.31.31.61.6-1.51.5-1.51.51.51.51.51.51.61.61.51.5-1.5-0.8-1.11.31.3
Delay disc. indifference point, 8s delay1.01.12.51.51.61.21.0-1.01.0-1.01.01.01.11.11.21.01.01.40.9-1.1-0.4-0.70.70.7
Indifference point function ln k1.11.92.9-1.5-1.5-1.6-1.31.6-1.61.6-1.6-1.6-1.6-1.7-0.7-1.7-1.7-1.1-1.70.5-0.6-0.60.80.8
Indifference point function log k1.11.92.9-1.5-1.5-1.6-1.31.6-1.61.6-1.6-1.6-1.6-1.7-0.7-1.7-1.7-1.1-1.70.5-0.6-0.60.80.8
Patch foraging total patch changes 0 sec0.20.30.6-0.4-0.4-0.3-0.60.5-0.50.5-0.5-0.5-0.5-0.5-0.3-0.6-0.6-0.4-0.70.60.80.6-0.7-0.7
Patch foraging total patch changes 12 sec0.30.31.3-0.6-0.6-0.3-0.30.1-0.10.1-0.1-0.1-0.3-0.2-0.7-0.1-0.1-0.5-0.20.71.01.1-1.1-1.1
Patch foraging total patch changes 18 sec0.40.73.7-0.2-0.2-0.2-0.30.1-0.10.1-0.1-0.1-0.1-0.0-0.7-0.0-0.0-0.5-0.11.01.51.6-1.9-1.9
Patch foraging total patch changes 24 sec1.01.72.51.11.11.51.0-1.61.6-1.61.61.61.51.50.51.51.51.21.5-0.31.30.8-0.8-0.8
Patch foraging total patch changes 6 sec0.71.15.1-0.6-0.6-0.1-0.70.3-0.30.3-0.3-0.3-0.3-0.3-0.5-0.4-0.4-0.9-0.41.41.92.1-2.2-2.2
Patch foraging time to switch 0 sec0.10.20.4-0.3-0.4-0.10.3-0.50.5-0.50.50.50.40.5-0.60.50.50.30.5-0.30.3-0.10.40.4
Patch foraging water rate 0 sec0.10.20.70.50.50.70.4-0.40.4-0.40.40.40.40.30.90.30.30.40.3-0.4-0.5-0.50.10.1
Patch foraging water rate 12 sec0.10.30.50.40.40.70.5-0.70.7-0.70.70.70.70.50.50.50.50.60.5-0.4-0.0-0.20.10.1
Patch foraging water rate 18 sec0.30.40.90.70.70.90.5-0.80.8-0.80.80.80.80.60.70.60.60.50.7-0.4-0.00.1-0.3-0.3
Patch foraging water rate 24 sec0.00.00.1-0.2-0.2-0.00.2-0.30.3-0.30.30.30.30.2-0.30.20.20.30.2-0.20.3-0.1-0.1-0.1
Patch foraging water rate 6 sec0.60.91.91.01.01.10.9-1.11.1-1.11.11.11.11.00.80.90.91.41.0-1.0-0.0-0.80.70.7
Seeking ratio, delayed vs. immediate footshock0.10.10.40.20.20.10.2-0.00.0-0.00.00.00.10.10.2-0.4-0.40.2-0.3-0.4-0.6-0.60.50.5
Distance traveled before self-admin0.70.92.6-1.5-1.6-1.3-0.91.0-1.01.0-1.0-1.0-1.0-1.0-1.2-0.8-0.8-1.0-0.80.70.40.3-0.5-0.5
Distance traveled after self-admin0.40.50.8-0.8-0.8-0.6-0.60.9-0.90.9-0.9-0.9-0.9-0.9-0.2-0.7-0.7-0.7-0.60.3-0.4-0.10.20.2
Extensor digitorum longus weight0.20.91.70.50.40.60.8-1.31.3-1.31.31.31.31.2-0.31.21.20.91.2-0.40.90.3-0.3-0.3
Bone: elastic displacement0.91.12.50.70.70.81.0-0.80.8-0.80.80.80.70.71.20.80.81.00.8-1.3-1.4-1.61.61.6
Bone: elastic work0.10.20.7-0.2-0.2-0.2-0.00.2-0.20.2-0.2-0.2-0.2-0.20.5-0.3-0.3-0.1-0.3-0.3-0.9-0.80.80.8
Bone: endosteal estimation0.81.72.4-1.5-1.4-1.4-1.51.5-1.51.5-1.5-1.5-1.5-1.5-1.1-1.5-1.5-1.4-1.61.10.50.6-0.3-0.3
Bone: endosteal perimeter1.02.22.7-1.5-1.5-1.6-1.61.6-1.61.6-1.6-1.6-1.6-1.6-1.4-1.6-1.6-1.6-1.61.50.91.1-1.0-1.0
Epididymis fat weight0.82.63.92.02.01.91.7-1.81.8-1.81.81.81.81.91.91.61.61.61.6-1.4-1.0-0.50.30.3
Delta time in closed arm before/after self-admin0.10.10.20.40.40.40.2-0.30.3-0.30.30.30.30.30.40.20.20.30.1-0.20.20.2-0.1-0.1
Delta time in open arm before/after self-admin1.51.52.81.01.01.41.3-1.11.1-1.11.11.11.11.11.71.21.21.01.1-1.3-1.5-1.31.41.4
Diff in mean of infusions in LGA sessions0.81.02.6-0.6-0.5-0.8-1.10.9-0.90.9-0.9-0.9-0.9-0.9-0.8-0.7-0.7-1.1-0.71.41.11.6-1.6-1.6
Delay discount exponential model param1.41.62.3-1.4-1.4-1.3-1.31.3-1.31.3-1.3-1.3-1.4-1.4-1.1-1.4-1.4-1.5-1.21.30.50.8-0.9-0.9
Extinction: sum of active levers before priming0.80.91.41.21.21.10.7-1.01.0-1.01.01.01.01.00.91.11.10.70.9-0.30.50.6-0.5-0.5
Active lever presses in extinction session 61.01.01.61.11.10.91.0-1.11.1-1.11.11.11.11.11.11.21.20.91.3-0.8-0.6-0.50.40.4
Bone: final force0.30.51.9-0.00.0-0.4-0.40.7-0.70.7-0.7-0.7-0.7-0.80.7-0.7-0.7-0.7-0.70.0-1.4-0.40.80.8
Bone: final moment0.30.42.00.10.1-0.3-0.30.6-0.60.6-0.6-0.6-0.5-0.60.8-0.6-0.6-0.5-0.7-0.1-1.4-0.50.90.9
Food consumed during 24 hour testing period0.30.43.10.50.6-0.00.30.2-0.20.2-0.2-0.2-0.1-0.20.8-0.1-0.1-0.0-0.1-0.6-1.8-0.90.90.9
Glucose0.30.41.0-0.7-0.7-0.7-0.70.7-0.70.7-0.7-0.7-0.7-0.8-0.5-1.0-1.0-0.6-0.90.3-0.1-0.20.10.1
Heart weight2.53.95.02.22.22.22.2-2.12.1-2.12.12.12.12.12.01.91.92.01.9-2.0-1.5-1.41.31.3
Delay discount hyperbolic model param1.51.72.4-1.5-1.5-1.3-1.41.3-1.31.3-1.3-1.3-1.4-1.4-1.2-1.5-1.5-1.5-1.31.30.60.9-1.0-1.0
Intermittent access intake day 1-15 change0.30.71.8-0.2-0.1-0.3-0.90.7-0.70.7-0.7-0.7-0.7-0.7-0.2-0.7-0.7-0.7-0.81.01.31.3-1.1-1.1
Intermittent access intake escalation0.40.82.6-0.10.1-0.2-0.90.7-0.70.7-0.7-0.7-0.7-0.7-0.2-0.7-0.7-0.6-0.71.11.61.6-1.4-1.4
Intermittent access intake escalation 20.50.53.20.30.40.6-0.3-0.10.1-0.10.10.10.10.10.3-0.0-0.0-0.10.00.81.81.8-1.3-1.3
Intermitt. access day 1 inactive lever presses0.10.40.70.60.60.80.7-0.70.7-0.70.70.70.70.70.80.70.70.60.7-0.6-0.3-0.2-0.0-0.0
Intermitt. access day 15 inactive lever presses1.73.54.91.91.81.72.0-1.91.9-1.91.91.91.91.91.81.71.72.01.8-2.2-1.7-1.91.91.9
Intermitt. access escalation Index0.30.41.1-0.7-0.8-0.4-0.60.4-0.40.4-0.4-0.4-0.4-0.4-0.5-0.3-0.3-0.6-0.40.81.01.0-1.0-1.0
Intermittent access day 1 total infusions0.30.52.00.50.50.10.6-0.30.3-0.30.30.30.30.30.40.50.50.60.5-0.9-1.4-1.41.11.1
Intermittent access day 15 total infusions0.10.21.00.91.00.40.3-0.10.1-0.10.10.10.10.10.70.40.40.50.3-0.5-0.5-0.40.30.3
Intermittent access terminal intake (last 3 days)0.10.10.20.00.1-0.2-0.20.4-0.40.4-0.4-0.4-0.4-0.40.2-0.2-0.2-0.1-0.2-0.1-0.4-0.30.10.1
Intermittent access total infusions0.40.51.40.80.80.40.6-0.30.3-0.30.30.30.30.30.80.60.60.70.6-0.9-1.2-1.10.80.8
Intermittent access day 1 locomotion0.20.21.0-0.2-0.3-0.20.4-0.20.2-0.20.20.20.20.2-0.20.40.40.20.4-0.6-1.0-0.90.60.6
Intermittent access day 15 total locomotion0.10.20.70.30.30.20.5-0.30.3-0.30.30.30.30.30.30.40.40.40.4-0.7-0.8-0.80.40.4
Intermittent access total locomotion0.10.20.90.20.1-0.10.4-0.30.3-0.30.30.30.30.3-0.10.50.50.30.4-0.6-1.0-0.80.30.3
Intermittent access standard deviation1.63.35.11.91.82.22.0-2.02.0-2.02.02.02.02.01.92.12.11.82.1-1.5-0.7-0.71.11.1
Left kidney weight4.721.931.95.65.74.95.0-4.94.9-4.94.94.94.94.94.94.84.84.84.6-4.7-3.8-3.32.82.8
Right kidney weight6.429.040.36.36.45.95.8-5.85.8-5.85.85.85.85.85.95.55.55.25.4-5.2-4.2-3.23.03.0
Cocaine induced anxiety0.10.10.4-0.2-0.20.20.4-0.20.2-0.20.20.20.20.20.30.30.30.10.3-0.5-0.6-0.50.70.7
Post-drug Anxiety0.10.10.2-0.2-0.30.20.5-0.40.4-0.40.40.40.40.40.20.50.50.20.5-0.4-0.3-0.50.30.3
Baseline Anxiety0.10.10.50.20.2-0.0-0.0-0.30.3-0.30.30.30.30.3-0.40.20.20.10.20.10.40.3-0.7-0.7
Tail length0.31.21.71.21.21.31.2-1.21.2-1.21.21.21.21.21.01.31.30.91.2-0.8-0.6-0.20.20.2
Length with tail1.25.39.23.03.02.82.4-2.42.4-2.42.42.42.42.32.92.32.32.02.2-2.0-1.9-0.91.11.1
Length without tail3.411.119.64.34.44.13.3-3.53.5-3.53.53.53.53.44.13.33.33.13.3-2.9-2.2-1.21.81.8
Times rat made contact with spout0.30.32.40.00.00.10.5-0.00.0-0.00.00.00.0-0.00.90.10.10.10.0-0.7-1.6-1.20.90.9
Lifetime Intake0.40.51.70.80.80.40.6-0.30.3-0.30.30.30.30.30.80.50.50.70.5-1.0-1.3-1.21.11.1
Liver weight, left0.30.50.80.70.70.40.9-0.70.7-0.70.70.70.80.90.40.80.80.90.9-0.8-0.7-0.90.00.0
Liver weight, right0.40.73.80.10.1-0.10.7-0.30.3-0.30.30.30.30.40.30.30.30.80.3-1.1-1.5-1.91.61.6
Locomotor activity0.10.20.60.1-0.00.20.5-0.30.3-0.30.30.30.40.40.30.30.30.40.3-0.5-0.8-0.70.70.7
Locomotor testing distance0.10.10.5-0.6-0.7-0.4-0.20.4-0.40.4-0.4-0.4-0.3-0.2-0.1-0.3-0.3-0.4-0.30.2-0.2-0.00.00.0
Locomotor testing rearing1.93.86.5-2.5-2.5-2.5-1.82.3-2.32.3-2.3-2.3-2.3-2.1-1.5-2.1-2.1-2.1-2.11.5-0.10.3-0.3-0.3
Locomotion in novel chamber1.92.43.31.41.31.61.7-1.81.8-1.81.81.81.81.81.51.71.71.41.8-1.5-0.8-0.70.80.8
Locomotion in novel chamber post-restriction0.10.20.30.50.60.50.4-0.50.5-0.50.50.50.40.40.30.60.60.10.5-0.2-0.00.1-0.1-0.1
Fecal boli incidents, locomotor time 10.10.10.90.10.00.50.1-0.30.3-0.30.30.30.30.30.00.30.30.20.30.21.00.6-0.5-0.5
Change in fecal boli incidents, locomotor task0.20.20.4-0.4-0.3-0.6-0.50.5-0.50.5-0.5-0.5-0.6-0.6-0.5-0.5-0.5-0.3-0.50.4-0.1-0.1-0.3-0.3
Time >=10cm from walls, locomotor time 10.70.71.0-0.6-0.5-0.8-1.00.9-0.90.9-0.9-0.9-1.0-1.0-0.5-0.9-0.9-0.9-0.90.80.50.6-0.9-0.9
Bouts of movement, locomotor time 10.30.31.70.30.30.20.4-0.10.1-0.10.10.10.10.10.30.10.10.50.1-0.8-1.1-1.31.21.2
Total resting periods, locomotor time 10.40.41.90.40.40.30.6-0.40.4-0.40.40.40.30.30.40.30.30.60.3-0.9-1.1-1.41.21.2
Rest time, locomotor task time 10.20.21.00.20.20.10.4-0.40.4-0.40.40.40.40.4-0.00.40.40.60.4-0.6-0.5-1.00.70.7
Distance moved, locomotor task time 10.91.41.9-1.1-1.1-1.1-1.21.1-1.11.1-1.1-1.1-1.1-1.1-0.9-1.3-1.3-1.4-1.41.40.91.3-1.1-1.1
Vertical activity count, locomotor time 10.20.51.3-0.5-0.5-0.5-0.70.8-0.80.8-0.8-0.8-0.8-0.80.2-1.0-1.0-1.1-1.00.6-0.20.5-0.2-0.2
Time >=10cm from walls, locomotor time 20.30.41.0-0.7-0.7-0.8-0.60.4-0.40.4-0.4-0.4-0.5-0.5-1.0-0.5-0.5-0.7-0.50.70.60.8-0.8-0.8
Bouts of movement, locomotor time 21.01.72.6-0.9-0.8-1.1-1.51.6-1.61.6-1.6-1.6-1.6-1.6-0.5-1.5-1.5-1.4-1.61.20.60.6-0.5-0.5
Total resting periods, locomotor time 20.30.61.0-0.4-0.3-0.5-0.81.0-1.01.0-1.0-1.0-1.0-1.00.2-1.0-1.0-0.8-1.00.5-0.10.00.10.1
Rest time, locomotor task time 20.50.71.90.30.20.80.8-0.70.7-0.70.70.70.70.70.90.50.50.80.6-1.0-1.2-1.41.21.2
Distance moved, locomotor task time 21.01.22.6-0.9-0.8-1.6-1.11.1-1.11.1-1.1-1.1-1.1-1.1-1.3-1.2-1.2-1.3-1.31.10.60.9-0.8-0.8
Vertical activity count, locomotor time 20.81.11.9-0.7-0.6-1.3-1.21.1-1.11.1-1.1-1.1-1.2-1.2-0.9-1.4-1.4-1.3-1.40.90.40.8-0.5-0.5
Light reinforcement 10.20.50.9-0.6-0.6-0.4-0.60.7-0.70.7-0.7-0.7-0.9-0.90.2-0.9-0.9-1.0-0.80.5-0.60.1-0.1-0.1
Light reinforcement 20.10.21.30.70.80.80.3-0.30.3-0.30.30.30.20.21.10.20.20.00.2-0.1-0.60.20.00.0
Bone: marrow area0.81.72.3-1.4-1.4-1.4-1.41.5-1.51.5-1.5-1.5-1.5-1.5-1.1-1.4-1.4-1.4-1.51.20.60.7-0.4-0.4
Bone: maximum diameter0.30.61.0-1.0-1.0-1.0-0.80.9-0.90.9-0.9-0.9-0.9-0.9-0.6-0.8-0.8-0.8-0.90.4-0.2-0.10.10.1
Bone: maximum force0.30.53.10.40.40.10.30.0-0.00.0-0.0-0.0-0.0-0.11.1-0.1-0.10.1-0.1-0.7-1.8-1.11.41.4
Bone: maximum moment0.40.73.50.50.50.20.5-0.10.1-0.10.10.10.10.11.20.10.10.20.0-0.9-1.9-1.31.61.6
Mean time between licks in bursts0.10.32.10.40.4-0.00.20.2-0.20.2-0.2-0.2-0.3-0.10.7-0.2-0.20.3-0.1-0.8-1.4-1.30.90.9
Mean num. licks in bursts0.00.00.3-0.1-0.2-0.20.00.2-0.20.2-0.2-0.2-0.2-0.0-0.10.00.00.3-0.0-0.20.0-0.50.40.4
Cd content in liver0.80.91.80.70.70.81.0-0.80.8-0.80.80.80.70.70.80.90.90.90.9-1.3-1.3-1.31.21.2
Co content in liver2.22.56.61.71.71.41.6-1.01.0-1.01.01.01.11.22.31.11.11.31.1-1.8-2.6-2.02.22.2
Cu content in liver2.83.34.92.22.22.02.0-1.81.8-1.81.81.81.91.92.21.81.81.61.8-1.7-1.8-1.21.31.3
Fe content in liver0.60.81.6-1.2-1.3-1.3-0.71.1-1.11.1-1.1-1.1-1.0-1.0-0.9-0.7-0.7-0.5-0.60.30.0-0.50.30.3
K content in liver0.00.00.20.20.2-0.00.1-0.00.0-0.00.00.00.20.10.4-0.0-0.00.00.1-0.1-0.5-0.20.10.1
Mg content in liver0.70.71.60.90.90.80.8-0.70.7-0.70.70.70.70.71.10.50.50.80.5-1.0-1.3-1.21.11.1
Mn content in liver0.91.02.0-1.1-1.1-1.1-1.01.1-1.11.1-1.1-1.1-1.1-1.3-0.6-1.4-1.4-1.1-1.40.6-0.3-0.20.10.1
Na content in liver0.30.40.7-0.3-0.2-0.5-0.50.9-0.90.9-0.9-0.9-0.7-0.80.4-0.6-0.6-0.6-0.50.4-0.7-0.00.20.2
Rb content in liver0.50.60.90.90.90.90.7-0.90.9-0.90.90.90.90.90.40.80.80.70.8-0.40.20.20.10.1
Se content in liver0.20.21.2-0.5-0.5-0.50.10.1-0.10.1-0.1-0.1-0.1-0.1-0.3-0.0-0.00.1-0.0-0.5-0.5-1.10.90.9
Sr content in liver0.40.31.0-0.4-0.4-0.5-0.50.4-0.40.4-0.4-0.4-0.4-0.4-0.8-0.2-0.2-0.5-0.20.71.00.9-1.0-1.0
Zn content in liver0.91.01.61.11.11.11.0-1.31.3-1.31.31.31.21.20.71.01.00.91.0-0.9-0.3-0.30.70.7
Bone: minimum diameter0.10.20.60.00.1-0.1-0.30.4-0.40.4-0.4-0.4-0.4-0.50.1-0.5-0.5-0.1-0.5-0.1-0.3-0.30.80.8
Time in familiar zone, hab. session 13.13.04.2-1.6-1.5-1.7-1.82.0-2.02.0-2.0-2.0-2.0-2.0-1.0-2.0-2.0-2.1-2.01.70.31.2-1.0-1.0
Time in novel zone, hab. session 11.31.31.81.00.91.21.2-1.31.3-1.31.31.31.31.20.91.31.31.31.3-1.2-0.4-0.90.80.8
Total zone transitions, hab. session 10.00.00.10.20.20.20.2-0.20.2-0.20.20.20.20.20.30.20.20.20.20.00.10.1-0.2-0.2
Total locomotion distance, hab. session 12.43.54.11.91.81.92.0-1.91.9-1.91.91.91.91.81.91.91.91.91.9-1.9-1.5-1.71.81.8
Locomotion velocity, hab. session 11.21.71.91.31.31.31.4-1.31.3-1.31.31.31.31.21.21.31.31.41.3-1.4-1.0-1.21.41.4
Time in familiar zone, hab. session 22.12.23.9-1.9-2.0-2.0-1.51.5-1.51.5-1.5-1.5-1.4-1.4-2.0-1.3-1.3-1.5-1.31.41.10.9-1.1-1.1
Time in novel zone, hab. session 20.80.82.41.31.41.40.8-0.80.8-0.80.80.80.70.71.50.60.60.70.6-0.7-0.7-0.30.60.6
Total zone transitions, hab. session 20.20.20.70.80.80.50.4-0.40.4-0.40.40.40.30.30.70.30.30.40.3-0.4-0.7-0.40.30.3
Total locomotion distance, hab. session 22.12.73.11.71.71.61.7-1.71.7-1.71.71.71.61.61.61.71.71.71.7-1.8-1.4-1.61.41.4
Locomotion velocity, hab. session 22.83.84.32.12.02.02.1-2.02.0-2.02.02.01.91.91.82.02.02.12.0-2.1-1.6-1.81.71.7
Novel to familiar place preference ratio0.70.81.30.90.90.90.9-0.90.9-0.90.90.90.90.80.70.80.81.10.8-1.1-0.5-1.01.11.1
Novelty place preference0.70.71.10.80.80.80.8-0.90.9-0.90.90.90.80.70.70.70.71.00.7-1.0-0.5-0.91.11.1
Time in novel zone, NPP test0.50.51.20.60.60.60.7-0.70.7-0.70.70.70.70.60.50.60.60.90.6-0.9-0.5-1.01.11.1
Total zone transitions, NPP test0.60.81.01.01.00.91.0-0.90.9-0.90.90.90.90.90.71.01.01.01.0-1.0-0.7-0.90.90.9
Total locomotion distance, NPP test2.43.34.61.71.71.61.9-1.81.8-1.81.81.81.71.71.61.71.71.91.7-2.1-1.7-2.12.12.1
Locomotion velocity, NPP test2.63.74.51.91.91.82.0-1.91.9-1.91.91.91.91.81.61.81.82.01.8-2.1-1.6-2.02.12.1
Intraocular pressure1.62.25.1-1.7-1.8-1.7-1.61.2-1.21.2-1.2-1.2-1.1-1.3-2.3-1.3-1.3-1.4-1.21.72.01.4-1.7-1.7
Delta distance traveled before/after self-admin0.30.41.70.60.70.50.20.3-0.30.3-0.3-0.3-0.3-0.31.2-0.3-0.30.1-0.3-0.4-1.3-0.81.01.0
Delta ambulatory time before/after self-admin0.50.63.00.70.80.40.40.1-0.10.1-0.1-0.1-0.1-0.11.3-0.1-0.10.3-0.1-0.8-1.7-1.31.41.4
Parametrial fat weight1.22.83.81.91.91.71.7-1.61.6-1.61.61.61.51.51.71.51.51.91.4-2.0-1.5-1.91.61.6
Pavlov. Cond. lever latency0.81.01.7-1.1-1.1-1.0-1.11.2-1.21.2-1.2-1.2-1.2-1.3-0.6-1.3-1.3-0.9-1.30.60.0-0.00.20.2
Pavlov. Cond. magazine entry latency0.10.10.4-0.4-0.4-0.5-0.20.4-0.40.4-0.4-0.4-0.4-0.3-0.0-0.4-0.4-0.6-0.40.2-0.6-0.10.00.0
Pavlov. Cond. change in total contacts0.80.81.41.21.21.00.9-0.90.9-0.90.90.90.91.01.21.11.10.41.1-0.4-0.60.2-0.5-0.5
Pavlov. Cond. index score0.40.50.80.90.90.70.8-0.80.8-0.80.80.80.80.90.80.80.80.50.8-0.6-0.7-0.30.10.1
Pavlov. Cond. latency score0.70.91.21.01.00.91.1-1.01.0-1.01.01.01.01.11.01.11.10.71.1-0.8-0.8-0.50.30.3
Pavlov. Cond. lever contacts0.91.11.81.21.11.01.1-1.21.2-1.21.21.21.21.30.71.31.30.91.3-0.7-0.2-0.1-0.2-0.2
Pavlov. Cond. magazine entry number0.00.00.20.00.00.20.0-0.20.2-0.20.20.20.10.1-0.10.20.20.30.2-0.10.4-0.00.10.1
Pavlov. Cond. intertrial magazine entries1.21.42.21.41.41.41.2-1.11.1-1.11.11.11.11.11.51.21.21.31.2-1.3-0.9-1.01.11.1
Pavlov. Cond. lever-magazine prob. diff.0.20.30.50.70.70.50.6-0.60.6-0.60.60.60.60.70.50.60.60.30.6-0.3-0.30.1-0.2-0.2
Pavlov. Cond. response bias0.00.00.20.10.1-0.20.00.0-0.00.0-0.0-0.00.00.0-0.0-0.0-0.0-0.2-0.00.2-0.10.3-0.4-0.4
Pavlov. Cond. lever latency0.91.24.5-1.0-1.1-1.0-0.90.5-0.50.5-0.5-0.5-0.5-0.4-1.8-0.5-0.5-0.7-0.51.32.11.5-1.7-1.7
Pavlov. Cond. magazine entry latency0.20.20.80.10.10.3-0.30.3-0.30.3-0.3-0.3-0.3-0.20.7-0.3-0.3-0.6-0.30.5-0.10.9-0.8-0.8
Pavlov. Cond. change in total contacts0.20.41.70.50.50.60.5-0.20.2-0.20.20.20.20.21.10.20.20.30.2-0.8-1.3-0.91.11.1
Pavlov. Cond. index score0.40.52.50.60.60.70.4-0.10.1-0.10.10.10.10.11.60.00.00.10.0-0.7-1.6-0.81.11.1
Pavlov. Cond. latency score0.30.42.60.60.60.70.3-0.00.0-0.00.00.00.0-0.01.6-0.1-0.1-0.1-0.1-0.5-1.6-0.60.90.9
Pavlov. Cond. lever contacts1.01.45.01.11.21.11.0-0.60.6-0.60.60.60.60.52.00.50.50.80.5-1.4-2.2-1.61.81.8
Pavlov. Cond. magazine entry number0.10.20.60.10.0-0.10.3-0.40.4-0.40.40.40.40.3-0.40.40.40.60.4-0.5-0.0-0.80.60.6
Pavlov. Cond. intertrial magazine entries0.71.12.60.70.60.41.1-1.01.0-1.01.01.01.00.90.11.01.01.31.0-1.3-0.8-1.61.41.4
Pavlov. Cond. lever-magazine prob. diff.0.40.52.60.60.60.80.4-0.10.1-0.10.10.10.10.01.60.00.00.10.0-0.7-1.6-0.71.11.1
Pavlov. Cond. response bias0.30.41.80.50.50.60.4-0.10.1-0.10.10.10.10.11.20.10.10.30.1-0.7-1.3-0.91.21.2
Time in closed arm before self-admin3.13.95.3-2.0-1.9-2.3-2.22.1-2.12.1-2.1-2.1-2.1-2.1-2.2-2.1-2.1-2.0-1.82.21.51.4-1.7-1.7
Time in closed arm after self-admin1.31.42.3-0.9-0.9-1.3-1.31.1-1.11.1-1.1-1.1-1.1-1.1-1.5-1.2-1.2-1.0-1.11.31.31.3-1.4-1.4
Time in open arm before self-admin0.10.21.00.30.30.1-0.1-0.20.2-0.20.20.20.20.2-0.5-0.0-0.00.1-0.40.21.00.9-0.6-0.6
Time in open arm after self-admin3.94.35.71.91.82.22.3-2.22.2-2.22.22.22.22.22.12.42.42.02.1-2.1-1.6-1.51.71.7
Bone: periosteal estimation0.40.91.4-0.9-0.8-1.0-0.91.1-1.11.1-1.1-1.1-1.2-1.2-0.3-1.1-1.1-0.9-1.20.3-0.7-0.40.70.7
Bone: periosteal perimeter0.71.22.0-1.2-1.1-1.2-1.11.3-1.31.3-1.3-1.3-1.4-1.4-0.6-1.4-1.4-1.2-1.40.6-0.5-0.20.30.3
Bone: post-yield work0.50.71.1-1.0-1.0-0.9-0.61.1-1.11.1-1.1-1.1-1.0-1.0-0.5-0.8-0.8-0.8-0.90.2-0.6-0.50.70.7
Progressive ratio test 1 active lever presses0.70.93.30.80.80.40.9-0.60.6-0.60.60.60.60.60.70.70.70.80.7-1.3-1.8-1.61.21.2
Progressive ratio test 1 breakpoint0.70.83.30.70.70.40.9-0.60.6-0.60.60.60.60.60.70.70.70.80.7-1.3-1.8-1.61.21.2
Progressive ratio test 1 inactive lever presses0.10.20.6-0.6-0.6-0.6-0.20.4-0.40.4-0.4-0.4-0.4-0.4-0.3-0.3-0.3-0.3-0.3-0.1-0.8-0.70.10.1
Progressive ratio test 2 active lever presses0.20.20.6-0.2-0.1-0.4-0.30.6-0.60.6-0.6-0.6-0.6-0.60.1-0.4-0.4-0.2-0.4-0.1-0.8-0.60.50.5
Progressive ratio test 2 breakpoint0.10.20.6-0.00.0-0.3-0.20.4-0.40.4-0.4-0.4-0.4-0.40.2-0.3-0.3-0.1-0.3-0.2-0.8-0.60.50.5
Progressive ratio test 2 inactive lever presses0.81.32.51.11.11.01.2-1.01.0-1.01.01.01.01.01.41.01.01.11.0-1.4-1.6-1.51.21.2
Incentive Sensitization - Responses0.40.60.8-0.8-0.7-0.6-0.90.9-0.90.9-0.9-0.9-0.9-0.9-0.4-0.8-0.8-0.8-0.80.80.60.5-0.3-0.3
Incentive Sensitization - Breakpoint0.30.40.6-0.6-0.6-0.5-0.80.8-0.80.8-0.8-0.8-0.8-0.8-0.3-0.7-0.7-0.7-0.70.70.60.5-0.2-0.2
Sum of active levers in priming session hrs 5-60.20.20.60.50.50.40.6-0.50.5-0.50.50.50.50.50.50.80.80.20.6-0.2-0.20.30.20.2
Progressive ratio3.25.17.5-2.1-2.1-1.9-2.42.0-2.02.0-2.0-2.0-2.0-2.0-2.5-2.1-2.1-2.5-2.02.72.42.6-2.7-2.7
Food seeking constrained by brief footshock0.81.01.9-1.2-1.2-0.9-1.11.1-1.11.1-1.1-1.1-1.2-1.2-0.7-0.9-0.9-1.4-1.01.00.60.7-0.5-0.5
Seeking ratio, punishment vs. effort0.91.22.50.90.90.91.1-0.90.9-0.90.90.90.90.91.31.21.21.21.0-1.3-1.3-1.41.61.6
Retroperitoneal fat weight2.08.411.93.43.43.03.1-3.03.0-3.03.03.03.02.93.42.82.82.62.7-3.0-3.0-2.12.02.0
Reaction time number correct3.16.08.0-2.7-2.7-2.8-2.62.7-2.72.7-2.7-2.7-2.6-2.8-2.3-2.7-2.7-2.7-2.72.10.81.3-1.3-1.3
Reaction time mean minus median0.00.10.30.40.40.4-0.00.0-0.00.0-0.0-0.0-0.1-0.10.6-0.1-0.1-0.1-0.1-0.1-0.5-0.10.30.3
Reaction time mean minus median AUC0.30.71.2-0.7-0.7-0.5-1.01.0-1.01.0-1.0-1.0-1.1-1.1-0.2-1.1-1.1-1.1-1.10.80.00.4-0.3-0.3
Reaction time num false alarms1.42.04.42.02.11.71.4-1.51.5-1.51.51.51.61.61.51.71.71.01.6-0.7-0.50.4-0.7-0.7
Reaction time num false alarms AUC1.52.44.62.12.21.91.6-1.71.7-1.71.71.71.81.71.61.91.91.21.8-0.8-0.40.4-0.5-0.5
Reaction time trials correct on left3.16.08.0-2.7-2.7-2.8-2.62.7-2.72.7-2.7-2.7-2.6-2.8-2.3-2.7-2.7-2.7-2.72.10.81.3-1.3-1.3
Reaction time trials on left3.05.77.5-2.7-2.7-2.7-2.52.6-2.62.6-2.6-2.6-2.6-2.7-2.2-2.7-2.7-2.7-2.72.10.71.2-1.3-1.3
Reaction time mean0.10.10.30.40.50.4-0.30.2-0.20.2-0.2-0.2-0.3-0.20.5-0.4-0.4-0.1-0.30.10.10.30.00.0
Reaction time mean AUC0.30.50.8-0.10.0-0.0-0.90.7-0.70.7-0.7-0.7-0.8-0.70.0-0.9-0.9-0.7-0.80.80.60.9-0.6-0.6
Median of all reaction times0.10.10.30.40.50.3-0.50.3-0.30.3-0.3-0.3-0.4-0.30.3-0.5-0.5-0.2-0.40.30.30.5-0.2-0.2
Reaction time omissions0.20.20.80.40.40.50.2-0.10.1-0.10.10.1-0.0-0.00.90.00.00.20.1-0.5-0.8-0.80.90.9
Reaction time false alarm rate5.17.011.13.33.33.22.9-2.92.9-2.92.92.92.93.02.83.03.02.53.0-2.0-1.2-0.70.50.5
Reaction time premature initiation rate0.00.00.1-0.1-0.1-0.1-0.10.2-0.20.2-0.2-0.2-0.3-0.3-0.1-0.1-0.10.0-0.2-0.2-0.2-0.30.30.3
Reaction time premature initiations1.52.63.6-1.9-1.8-1.9-1.81.8-1.81.8-1.8-1.8-1.8-1.9-1.7-1.8-1.8-1.6-1.81.30.70.8-0.8-0.8
Std. dev. reaction times0.10.10.60.70.80.70.1-0.20.2-0.20.20.20.10.10.80.10.10.30.1-0.3-0.4-0.20.40.4
Reaction time trials completed3.05.77.5-2.7-2.7-2.7-2.52.6-2.62.6-2.6-2.6-2.6-2.7-2.2-2.7-2.7-2.7-2.72.10.71.2-1.3-1.3
Reaction time trials AUC2.44.76.4-2.4-2.4-2.5-2.32.4-2.42.4-2.4-2.4-2.3-2.5-2.1-2.4-2.4-2.4-2.41.80.71.1-1.1-1.1
Run reversals in cocaine runway, females0.10.10.20.30.30.20.2-0.20.2-0.20.20.20.20.20.00.10.10.50.0-0.3-0.2-0.4-0.0-0.0
Run reversals in cocaine runway, males0.20.20.6-0.7-0.8-0.4-0.50.5-0.50.5-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.2-0.50.30.50.2-0.0-0.0
Latency to leave start box in cocaine runway0.10.10.1-0.1-0.20.20.2-0.30.3-0.30.30.30.30.3-0.00.40.40.20.3-0.2-0.0-0.10.30.3
Latency to leave start box in cocaine runway, F1.11.32.2-1.4-1.5-1.1-1.21.0-1.01.0-1.0-1.0-1.0-1.0-1.1-1.1-1.1-1.4-1.11.31.01.1-1.0-1.0
Latency to leave start box in cocaine runway, M4.23.95.51.81.81.92.1-2.12.1-2.12.12.12.12.11.42.22.22.32.1-2.2-1.4-1.81.71.7
Std. dev. time between licks in bursts0.00.10.30.30.3-0.0-0.10.2-0.20.2-0.2-0.2-0.2-0.20.4-0.3-0.3-0.1-0.2-0.1-0.6-0.20.20.2
Total sessions with >9 infusions0.20.21.20.40.40.20.3-0.10.1-0.10.10.10.10.10.60.10.10.40.2-0.7-1.1-1.00.80.8
Short access day 1 total inactive lever presses2.43.14.71.71.71.42.0-1.81.8-1.81.81.81.81.81.51.91.91.81.8-2.2-2.1-2.11.31.3
Short access day 10 total inactive lever presses0.51.11.41.21.21.21.1-1.11.1-1.11.11.11.11.11.01.01.01.21.0-1.1-0.5-0.70.90.9
Short access day 1 total infusions0.30.41.40.30.30.20.6-0.40.4-0.40.40.40.40.40.50.40.40.50.4-0.9-1.2-1.01.01.0
Short access day 10 total infusions0.40.50.8-0.5-0.5-0.9-0.70.9-0.90.9-0.9-0.9-0.9-0.9-0.6-0.7-0.7-0.6-0.70.5-0.1-0.0-0.3-0.3
Short access total infusions0.20.31.20.50.60.10.3-0.00.0-0.00.00.00.00.00.50.10.10.40.2-0.7-1.1-1.00.90.9
Short access day 1 locomotion0.20.30.6-0.8-0.8-0.7-0.50.6-0.60.6-0.6-0.6-0.6-0.6-0.3-0.5-0.5-0.5-0.60.2-0.4-0.20.10.1
Short access day 10 total locomotion0.10.21.30.20.20.20.4-0.40.4-0.40.40.40.40.40.40.30.30.30.3-0.6-1.1-1.10.40.4
Short access total locomotion0.10.20.3-0.4-0.4-0.5-0.50.5-0.50.5-0.5-0.5-0.5-0.5-0.2-0.5-0.5-0.4-0.50.2-0.4-0.3-0.2-0.2
One hour access (0.3 mA shock)0.60.61.1-0.7-0.6-0.9-0.81.0-1.01.0-1.0-1.0-1.0-1.0-0.6-1.0-1.0-0.6-0.90.4-0.2-0.20.20.2
Compulsive drug intake0.30.30.6-0.6-0.7-0.3-0.60.5-0.50.5-0.5-0.5-0.5-0.5-0.1-0.8-0.8-0.7-0.70.70.60.6-0.4-0.4
One hour access (shock baseline)0.10.10.3-0.00.0-0.4-0.10.4-0.40.4-0.4-0.4-0.4-0.4-0.2-0.1-0.10.0-0.2-0.3-0.6-0.50.60.6
Social response proportion0.80.92.9-0.6-0.5-0.6-0.90.6-0.60.6-0.6-0.6-0.7-0.7-0.7-0.9-0.9-1.1-0.81.20.71.6-1.7-1.7
Social responses0.20.30.7-0.3-0.3-0.2-0.50.5-0.50.5-0.5-0.5-0.6-0.60.4-0.8-0.8-0.8-0.70.4-0.50.30.10.1
Social time0.50.75.0-0.4-0.4-0.00.20.5-0.50.5-0.5-0.5-0.4-0.31.1-0.4-0.4-0.4-0.4-0.6-2.2-1.31.41.4
Soleus weight0.41.12.71.61.61.41.0-1.21.2-1.21.21.21.11.11.21.21.20.81.2-0.6-0.30.2-0.1-0.1
Bone: stiffness0.20.31.0-0.1-0.0-0.4-0.20.6-0.60.6-0.6-0.6-0.6-0.60.4-0.6-0.6-0.4-0.5-0.0-1.0-0.40.60.6
Tibialis anterior weight0.31.01.61.00.90.91.0-1.21.2-1.21.21.21.21.10.51.21.21.01.2-0.8-0.0-0.20.40.4
Time to tail flick, vehicle, before self-admin0.90.92.8-0.9-0.9-1.1-1.10.7-0.70.7-0.7-0.7-0.7-0.7-1.7-0.8-0.8-0.9-0.81.11.31.2-1.1-1.1
Time to tail flick, vehicle, after self-admin0.50.62.4-0.5-0.5-0.7-0.70.4-0.40.4-0.4-0.4-0.4-0.4-1.1-0.2-0.2-0.6-0.21.01.21.5-1.5-1.5
Time to tail flick, test, before self-admin0.70.71.6-1.0-1.0-1.1-0.90.8-0.80.8-0.8-0.8-0.8-0.8-1.2-0.8-0.8-0.8-0.90.80.60.6-0.4-0.4
Time to tail flick, test, after self-admin0.70.81.3-1.1-1.1-1.0-0.71.0-1.01.0-1.0-1.0-1.0-1.0-0.3-0.8-0.8-0.7-0.60.2-0.7-0.70.80.8
Delta time to tail flick, vehicle, before/after SA0.40.41.00.60.50.80.6-0.60.6-0.60.60.60.60.61.00.70.70.40.8-0.4-0.40.00.10.1
Delta time to tail flick, test, before/after SA0.10.10.5-0.1-0.20.30.2-0.10.1-0.10.10.10.10.10.70.10.10.10.3-0.3-0.6-0.70.50.5
Tibia length2.67.39.43.02.92.92.8-3.03.0-3.03.03.03.03.02.43.13.12.93.1-2.6-1.0-1.41.71.7
Ambulatory time before self-admin0.71.02.1-1.4-1.4-1.3-1.01.1-1.11.1-1.1-1.1-1.1-1.1-1.2-0.9-0.9-1.0-0.90.80.50.5-0.7-0.7
Ambulatory time after self-admin0.40.53.00.30.30.10.50.1-0.10.1-0.1-0.1-0.1-0.10.70.10.10.30.2-0.9-1.7-1.51.41.4
Bone: tissue strength0.70.81.1-0.6-0.5-1.0-1.01.0-1.01.0-1.0-1.0-1.0-1.0-0.5-1.1-1.1-1.0-1.00.90.30.6-0.6-0.6
Total heroin consumption0.30.30.70.50.50.40.6-0.50.5-0.50.50.50.50.50.70.70.70.40.7-0.6-0.7-0.40.80.8
Bone: trabecular number5.99.812.0-3.5-3.5-3.3-3.23.3-3.33.3-3.3-3.3-3.2-3.1-3.1-3.1-3.1-3.4-3.13.32.22.6-2.7-2.7
Bone: trabecular spacing1.21.62.21.41.41.31.3-1.41.4-1.41.41.41.31.30.81.31.31.51.4-1.3-0.6-1.10.90.9
Bone: trabecular thickness3.54.45.8-2.3-2.2-2.3-2.22.4-2.42.4-2.4-2.4-2.4-2.3-1.6-2.4-2.4-2.3-2.41.90.61.1-1.0-1.0
Bone: trabecular tissue density1.82.75.62.02.01.51.6-1.31.3-1.31.31.31.41.22.11.21.21.51.2-1.8-2.4-1.92.02.0
Water consumed over 24 hours0.20.20.4-0.6-0.6-0.5-0.40.5-0.50.5-0.5-0.5-0.4-0.6-0.2-0.6-0.6-0.6-0.60.3-0.20.0-0.1-0.1
Number of responses in last shaping day0.91.01.5-0.9-0.8-1.2-0.91.2-1.21.2-1.2-1.2-1.2-1.2-0.4-1.2-1.2-0.8-1.10.1-1.0-0.60.60.6