Hub : Genes

Aplp1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL gene expression Aplp1 0.17 0.12 2.6e-03 0.03 0.02 -0.01 0.01 8.4e-02 1.0e-01 4.9e-01 1.7e-01
2 Adipose gene expression Aplp1 0.11 0.09 4.3e-04 0.02 0.03 0.03 0.02 2.9e-03 2.4e-04 2.7e-04 3.3e-03
3 Brain intron excision ratio chr1_94829566_94830353 0.04 0.03 3.4e-06 0.05 0.06 0.05 0.05 2.0e-05 2.3e-06 1.2e-05 1.7e-05
4 Brain intron excision ratio chr1_94830427_94830956 0.04 0.03 7.1e-06 0.03 0.06 0.04 0.05 3.8e-04 7.6e-06 4.3e-05 2.8e-05
5 PL mRNA stability Aplp1 0.19 0.09 2.5e-10 0.1 0.09 0.09 0.09 1.3e-10 3.0e-10 6.8e-10 4.8e-10
6 IL mRNA stability Aplp1 0.62 0.14 5.9e-08 0.24 0.19 0.18 0.22 2.0e-06 2.4e-05 4.7e-05 5.2e-06
7 BLA mRNA stability Aplp1 0.11 0.07 7.4e-03 0.03 0.01 0.04 0.03 7.0e-03 6.5e-02 2.7e-03 7.4e-03
8 PL intron excision ratio chr1_94825541_94826146 0.04 0.04 1.6e-03 0.02 0.03 0.03 0.02 4.0e-03 5.7e-04 5.5e-04 1.2e-03
9 PL intron excision ratio chr1_94825538_94826146 0.21 0.1 3.3e-08 0.06 0.08 0.07 0.07 7.3e-07 4.0e-09 1.4e-08 1.9e-08
10 PL isoform ratio NM_001399814.1 0.3 0.12 1.5e-12 0.09 0.12 0.1 0.1 1.6e-09 2.8e-13 2.1e-11 4.4e-11
11 NAcc intron excision ratio chr1_94825538_94826146 0.08 0.04 4.0e-08 0.06 0.06 0.05 0.06 2.7e-09 1.0e-08 7.1e-08 1.0e-08
12 NAcc isoform ratio NM_001399814.1 0.05 0.03 1.5e-04 0.03 0.02 0.02 0.02 1.8e-05 3.4e-04 2.8e-04 1.7e-04
13 BLA intron excision ratio chr1_94825538_94826146 0.18 0.1 2.0e-03 0.01 0.04 0.05 0.03 8.3e-02 2.5e-03 1.7e-03 1.2e-02
14 pVTA intron excision ratio chr1_94825538_94826146 0.08 0.05 1.2e-03 0.03 0.04 0.03 0.03 2.2e-03 6.5e-04 1.8e-03 3.2e-03
15 IC isoform ratio NM_001399814.1 0.15 0.09 2.5e-03 0.06 0.06 0.05 0.05 1.6e-03 2.3e-03 4.6e-03 4.0e-03
16 pVTA mRNA stability Aplp1 0.12 0.07 3.1e-05 0.06 0.05 0.05 0.06 8.7e-06 3.8e-05 1.1e-04 2.6e-05
17 LHb mRNA stability Aplp1 0.6 0.13 1.2e-10 0.45 0.38 0.42 0.44 6.0e-12 7.7e-10 2.8e-11 1.0e-11
18 NAcc mRNA stability Aplp1 0.14 0.06 9.1e-14 0.09 0.1 0.09 0.1 8.7e-13 2.3e-14 1.5e-13 2.4e-14
19 Brain mRNA stability Aplp1 0.31 0.1 0.0e+00 0.22 0.22 0.23 0.23 2.4e-20 7.6e-20 8.1e-21 3.3e-21
20 Brain intron excision ratio chr1_94825538_94826146 0.26 0.13 1.4e-11 0.12 0.12 0.1 0.14 1.6e-11 5.2e-11 1.3e-09 7.0e-13
21 Brain isoform ratio NM_001399814.1 0.27 0.13 3.0e-09 0.09 0.1 0.09 0.11 1.0e-08 7.7e-10 5.4e-09 3.7e-10
22 IC intron excision ratio chr1_94825538_94826146 0.24 0.11 2.2e-05 0.1 0.09 0.12 0.12 6.5e-05 1.7e-04 9.6e-06 1.2e-05
23 BLA isoform ratio NM_001399814.1 0.23 0.11 3.5e-04 0.04 0.06 0.05 0.05 5.8e-03 6.3e-04 1.2e-03 9.7e-04
24 Brain gene expression Aplp1 0.09 0.05 3.8e-04 0.06 0.03 0.05 0.05 4.6e-06 1.5e-03 1.3e-05 2.3e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density0.81.42.30.80.1-1.31.3-1.5-1.4-0.21.41.11.11.11.1-0.21.41.5-1.5-1.5-1.2-1.11.41.31.41.00.0
Area under the delay curve0.60.71.61.0-1.3-0.20.10.40.51.1-0.3-1.0-0.8-0.6-0.6-1.3-0.9-0.80.80.91.00.8-1.0-1.2-0.7-0.90.5
BMI with tail0.20.71.3-0.4-0.00.7-0.70.30.60.6-0.9-0.9-0.9-0.8-0.8-0.7-0.9-1.01.01.10.90.9-1.2-1.1-1.0-0.90.0
BMI without tail0.10.41.41.2-1.0-0.50.5-0.3-0.11.10.2-0.7-0.40.0-0.1-0.9-0.4-0.30.40.40.60.3-0.6-0.8-0.5-0.50.0
Body weight1.35.514.03.2-2.0-3.73.7-2.9-2.71.23.11.41.52.92.8-1.62.32.6-2.5-2.4-1.6-2.11.91.31.71.10.0
Weight adjusted by age0.10.10.4-0.60.2-0.20.2-0.4-0.40.30.20.60.40.40.6-0.70.50.3-0.4-0.4-0.3-0.30.30.20.2-0.30.0
Bone surface0.40.82.71.6-1.3-1.61.5-0.8-0.81.11.30.00.10.70.7-1.10.60.9-1.0-1.0-0.2-0.40.70.30.50.10.0
Bone volume0.61.13.01.5-1.0-1.71.7-1.2-1.10.91.50.40.41.01.0-0.91.01.3-1.3-1.3-0.6-0.81.00.70.90.40.0
Breakpoint value in progressive ratio session0.40.43.01.7-1.5-0.80.8-0.1-0.20.90.4-0.7-0.5-0.00.0-0.7-0.4-0.30.40.30.50.2-0.5-0.6-0.7-0.20.0
Number of licking bursts2.54.16.4-2.40.42.4-2.42.52.50.6-2.5-1.9-2.1-2.3-2.3-1.0-2.1-2.22.12.21.92.1-2.1-1.9-1.9-1.90.0
Context. condit. distance diff. score0.80.91.7-0.0-0.70.3-0.40.60.61.0-0.7-1.3-1.3-1.1-1.1-1.3-1.0-0.90.91.01.21.2-1.1-1.3-1.1-1.20.0
Locomotion velocity, session 10.40.41.6-0.61.20.3-0.2-0.3-0.1-0.40.30.40.40.50.51.30.40.5-0.6-0.8-0.7-0.70.91.00.81.00.0
Locomotion distance, session 10.40.54.10.8-1.1-0.60.50.20.52.00.3-1.0-0.9-0.2-0.3-1.2-0.4-0.0-0.0-0.10.60.4-0.1-0.4-0.3-0.50.0
Locomotion velocity, session 20.30.31.5-0.50.30.8-0.81.21.20.3-0.5-0.3-0.2-0.5-0.50.9-0.6-0.40.30.30.30.2-0.10.1-0.20.00.0
Locomotion distance, session 21.92.75.1-1.3-0.11.6-1.72.12.12.2-1.6-2.0-2.0-1.5-1.5-0.3-1.9-1.81.81.61.81.5-1.6-1.5-1.8-1.60.0
Locomotion velocity, session 30.20.20.8-0.70.10.5-0.60.90.90.8-0.5-0.4-0.5-0.3-0.3-0.1-0.4-0.30.30.30.40.3-0.3-0.2-0.3-0.50.0
Locomotion distance, session 32.12.312.01.8-2.9-1.10.90.91.13.50.2-1.7-1.5-0.6-0.6-2.5-1.0-0.60.70.81.51.2-1.2-1.6-1.4-1.80.0
Stereotopy head waving bouts, day 31.51.85.7-0.72.00.3-0.1-1.0-1.1-2.40.41.81.71.01.02.01.20.9-0.9-1.0-1.6-1.41.31.61.41.80.0
Stereotopy head waving duration, day 31.51.87.8-1.22.40.7-0.5-0.8-1.0-2.8-0.01.71.60.80.72.31.00.6-0.6-0.7-1.5-1.31.11.51.31.70.0
Locomotion velocity, session 70.50.52.60.7-1.2-0.30.20.40.41.6-0.0-1.0-0.9-0.2-0.2-1.1-0.6-0.40.50.50.90.6-0.7-0.9-0.8-0.90.0
Locomotion distance, session 70.10.21.30.4-0.5-0.50.50.1-0.11.10.5-0.3-0.30.50.5-0.20.20.4-0.3-0.40.0-0.30.20.10.0-0.10.0
Stereotopy head waving bouts, day 71.82.13.4-1.50.21.7-1.71.71.80.4-1.8-1.4-1.5-1.6-1.6-0.3-1.6-1.61.61.71.41.5-1.6-1.4-1.4-1.30.0
Stereotopy head waving duration, day 71.11.33.1-1.71.01.8-1.71.01.2-0.5-1.6-0.7-0.8-1.3-1.30.4-1.1-1.31.31.40.81.0-1.2-0.9-0.9-0.60.0
Locomotion velocity, session 83.13.75.9-2.00.62.4-2.42.12.21.0-2.3-1.9-2.0-2.2-2.2-0.4-2.2-2.12.22.21.92.0-2.0-1.8-2.0-1.70.0
Locomotion distance, session 82.84.17.0-0.9-1.01.4-1.62.32.22.5-1.8-2.6-2.6-2.0-2.0-1.4-2.3-2.02.12.02.42.2-2.2-2.2-2.3-2.30.0
Degree of sensitization distance1.11.13.5-0.71.50.1-0.0-0.7-1.0-1.90.51.10.90.90.91.51.00.9-1.0-1.0-1.2-1.11.21.31.11.30.0
Degree of sensitization stereotypy2.83.04.8-1.3-0.41.6-1.72.02.21.0-1.9-1.8-1.9-1.9-2.0-1.0-1.9-1.91.92.01.81.9-2.0-1.9-1.9-1.80.0
Conditioned locomotion0.60.71.4-0.40.11.0-1.00.70.80.1-1.0-0.9-0.8-1.2-1.10.2-1.1-1.11.11.10.91.0-1.0-0.9-0.9-0.60.0
Cocaine response after cond. corrected1.11.33.2-0.21.3-0.20.3-1.2-0.8-1.80.61.61.60.70.71.51.21.1-1.0-1.1-1.4-1.11.31.41.41.40.0
Cocaine response after cond. not corrected2.22.65.0-0.01.5-0.50.7-1.4-1.1-2.21.12.12.11.21.22.11.71.6-1.6-1.7-1.9-1.61.92.02.02.00.0
Cocaine response before conditioning0.70.81.91.2-1.0-1.31.3-0.2-0.40.11.40.40.41.01.0-0.10.91.1-1.2-1.2-0.6-0.81.00.80.80.50.0
Saline control response0.20.32.5-0.20.70.10.0-0.3-0.2-0.80.20.50.50.40.51.60.40.4-0.4-0.4-0.6-0.50.50.60.60.80.0
Bone: connectivity density0.10.20.40.6-0.5-0.60.6-0.3-0.20.40.50.30.30.10.1-0.60.40.5-0.5-0.5-0.3-0.20.50.40.50.10.0
Bone: cortical apparent density0.50.72.4-1.61.01.3-1.30.70.80.2-1.2-0.7-0.8-0.9-0.90.4-0.8-0.90.80.90.60.7-0.7-0.6-0.6-0.50.0
Bone: cortical area1.11.73.11.6-0.5-1.81.8-1.5-1.5-0.11.71.11.11.71.70.11.51.5-1.5-1.5-1.2-1.41.21.01.21.00.0
Bone: cortical porosity3.53.87.6-1.0-1.01.6-1.72.72.81.4-2.0-1.8-1.8-2.3-2.2-1.6-2.1-2.22.12.22.02.2-2.1-2.0-2.0-2.10.0
Bone: cortical porosity4.54.99.2-1.3-1.01.9-2.02.93.01.5-2.3-2.2-2.2-2.5-2.5-1.6-2.4-2.42.42.42.32.5-2.4-2.3-2.3-2.40.0
Bone: cortical thickness0.81.42.01.00.1-1.21.3-1.4-1.4-0.51.31.21.21.41.40.31.41.3-1.3-1.3-1.2-1.41.21.11.31.10.0
Bone: cortical thickness0.20.21.3-0.91.10.6-0.5-0.0-0.1-0.6-0.40.30.30.20.21.10.1-0.00.00.1-0.4-0.30.10.20.20.50.0
Bone: cortical tissue density0.71.02.7-1.71.01.5-1.50.91.00.3-1.4-0.9-1.0-1.1-1.10.3-1.0-1.11.01.10.80.9-0.9-0.7-0.8-0.70.0
Condit. Reinf. active minus inactive responses0.10.10.2-0.30.40.5-0.5-0.00.2-0.1-0.4-0.2-0.1-0.4-0.40.0-0.3-0.40.40.40.20.3-0.3-0.2-0.3-0.10.0
Condit. Reinf. active-inactive response ratio0.70.82.1-0.21.30.2-0.0-1.2-0.9-1.40.21.31.40.60.60.90.80.6-0.5-0.6-1.0-0.90.81.00.91.10.0
Condit. Reinf. active responses1.51.83.2-1.40.71.8-1.81.11.30.4-1.7-1.3-1.3-1.7-1.70.0-1.6-1.61.61.51.21.5-1.4-1.2-1.3-0.90.0
Condit. Reinf. inactive responses3.74.56.8-1.5-0.22.1-2.12.42.51.6-2.2-2.5-2.6-2.6-2.6-0.6-2.5-2.32.22.22.32.5-2.2-2.1-2.3-1.90.0
Incentive salience index mean0.20.30.6-0.20.00.6-0.60.30.60.3-0.6-0.6-0.5-0.8-0.8-0.2-0.7-0.70.70.60.60.6-0.6-0.5-0.6-0.40.0
Condit. Reinf. lever presses0.40.61.00.2-0.70.4-0.50.60.90.8-0.5-0.9-0.8-1.0-1.0-0.7-1.0-0.90.90.70.91.0-0.7-0.7-0.9-0.90.0
Condit. Reinf. active minus inactive responses0.40.52.61.6-1.0-1.21.2-0.5-0.60.51.00.40.60.60.7-0.20.50.7-0.7-0.7-0.4-0.50.60.50.50.50.0
Condit. Reinf. active-inactive response ratio0.00.00.2-0.20.40.2-0.1-0.1-0.1-0.3-0.10.20.1-0.1-0.00.20.10.1-0.00.0-0.2-0.10.10.10.20.20.0
Condit. Reinf. active responses0.91.26.12.5-2.1-1.91.8-0.5-0.61.31.60.20.40.90.9-1.10.60.9-1.0-1.0-0.3-0.50.70.40.50.20.0
Condit. Reinf. inactive responses1.11.49.12.5-3.0-1.81.60.40.42.11.2-0.7-0.40.30.2-1.9-0.10.2-0.3-0.30.60.3-0.1-0.5-0.4-0.90.0
Condit. Reinf. lever presses2.73.812.93.6-2.3-3.13.1-1.7-1.90.92.81.01.32.02.0-1.41.72.0-2.0-2.1-1.2-1.51.71.21.41.00.0
Condit. Reinf. lever reinforcers received0.91.36.52.6-2.4-1.91.8-0.2-0.41.71.5-0.20.00.70.7-1.60.40.8-0.8-0.80.0-0.20.50.10.3-0.20.0
Conditioned reinforcement - actives0.10.21.1-1.00.80.8-0.70.90.8-0.4-0.5-0.1-0.2-0.2-0.21.0-0.1-0.10.10.2-0.1-0.1-0.00.20.10.30.0
Conditioned reinforcement - inactives2.33.45.00.5-2.10.6-0.71.92.02.1-1.2-2.2-2.1-1.9-1.9-1.9-2.1-2.01.91.92.22.1-2.0-2.1-2.2-2.20.0
Conditioned locomotion1.11.43.2-1.50.91.8-1.71.51.4-0.2-1.6-0.9-1.0-1.3-1.30.8-1.2-1.41.31.40.80.9-1.1-0.8-1.0-0.50.0
Patch foraging indifference point 0 sec0.00.10.50.3-0.7-0.10.10.50.50.10.00.00.2-0.4-0.4-0.2-0.1-0.10.10.10.20.3-0.1-0.1-0.1-0.30.0
Patch foraging indifference point AUC0.20.30.9-1.00.70.9-0.90.50.6-0.2-0.8-0.1-0.1-0.7-0.60.2-0.4-0.60.60.60.30.5-0.4-0.2-0.4-0.20.0
Delay disc. indifference point, 0s delay2.32.55.90.9-1.40.2-0.30.70.72.1-0.8-2.4-2.3-1.7-1.6-1.4-1.8-1.51.51.51.91.9-1.7-2.0-1.7-1.41.9
Delay disc. indifference point, 16s delay0.91.02.71.6-1.6-0.30.20.50.61.2-0.2-1.2-0.8-0.7-0.8-1.2-1.0-1.01.01.01.21.1-1.2-1.3-0.7-1.00.4
Delay disc. indifference point, 2s delay0.60.72.61.1-1.5-0.60.50.20.21.60.2-1.1-1.1-0.1-0.0-0.9-0.6-0.40.40.40.90.6-0.7-0.9-0.7-0.81.6
Delay disc. indifference point, 24s delay0.50.63.01.6-1.7-1.11.0-0.3-0.21.20.6-0.3-0.1-0.1-0.1-1.6-0.1-0.10.10.10.50.3-0.3-0.6-0.0-0.70.6
Delay disc. indifference point, 4s delay1.01.02.10.2-0.90.5-0.61.31.51.1-0.7-1.2-1.0-0.9-0.9-1.1-1.1-1.11.01.11.21.0-1.1-1.1-1.1-1.10.6
Delay disc. indifference point, 8s delay0.10.11.30.5-0.6-0.20.20.00.10.50.0-0.2-0.0-0.2-0.1-1.2-0.1-0.10.10.20.20.1-0.3-0.40.0-0.40.0
Indifference point function ln k0.10.20.80.9-0.4-0.70.7-0.4-0.70.40.70.00.00.70.70.40.30.5-0.5-0.4-0.3-0.60.30.30.30.40.0
Indifference point function log k0.10.20.80.9-0.4-0.70.7-0.4-0.70.40.70.00.00.70.70.40.30.5-0.5-0.4-0.3-0.60.30.30.30.40.0
Patch foraging total patch changes 0 sec0.00.10.70.4-0.8-0.30.20.60.50.20.1-0.00.1-0.3-0.3-0.2-0.1-0.10.10.00.20.3-0.1-0.1-0.0-0.30.0
Patch foraging total patch changes 12 sec0.10.10.60.20.10.1-0.00.30.3-0.50.10.50.7-0.10.00.60.20.1-0.1-0.2-0.3-0.10.30.40.40.40.0
Patch foraging total patch changes 18 sec0.40.51.2-0.6-0.50.5-0.61.11.10.6-0.7-0.6-0.6-0.9-1.0-1.0-0.6-0.70.70.60.70.8-0.6-0.6-0.6-1.00.0
Patch foraging total patch changes 24 sec0.30.53.00.6-1.3-0.60.40.40.51.20.1-0.7-0.7-0.4-0.3-1.7-0.3-0.10.10.10.60.7-0.4-0.7-0.4-0.90.0
Patch foraging total patch changes 6 sec0.00.10.4-0.2-0.2-0.00.00.30.3-0.4-0.00.50.6-0.2-0.10.10.20.1-0.1-0.2-0.20.00.20.30.2-0.00.0
Patch foraging time to switch 0 sec0.20.32.2-0.61.10.7-0.60.20.2-1.5-0.30.40.6-0.0-0.01.50.1-0.00.00.0-0.3-0.20.20.40.40.60.0
Patch foraging water rate 0 sec0.30.71.4-1.20.11.0-1.01.00.90.3-1.1-0.5-0.6-0.9-0.8-0.0-0.8-0.90.90.90.70.8-0.8-0.7-0.9-0.80.0
Patch foraging water rate 12 sec0.30.64.80.1-1.7-0.60.51.00.71.50.1-0.6-0.8-0.2-0.2-2.2-0.20.1-0.00.10.50.4-0.3-0.6-0.5-1.00.0
Patch foraging water rate 18 sec0.10.10.3-0.6-0.00.3-0.30.60.60.3-0.3-0.1-0.2-0.3-0.3-0.4-0.2-0.10.10.20.10.2-0.1-0.1-0.1-0.20.0
Patch foraging water rate 24 sec2.73.88.2-0.2-1.80.7-0.92.11.92.9-1.4-2.4-2.5-1.7-1.7-2.2-2.0-1.91.92.02.32.1-2.2-2.3-2.2-2.40.0
Patch foraging water rate 6 sec0.91.36.20.6-2.2-0.70.51.00.82.1-0.1-1.1-1.3-0.7-0.6-2.5-0.7-0.50.40.51.11.0-0.8-1.1-0.9-1.60.0
Seeking ratio, delayed vs. immediate footshock1.21.56.01.3-2.0-0.60.40.70.71.9-0.0-1.5-1.5-0.8-0.8-2.5-0.9-0.80.70.81.31.4-1.2-1.6-1.1-1.50.0
Distance traveled before self-admin0.20.21.51.2-0.7-0.20.20.60.40.40.3-0.9-0.8-0.2-0.00.9-0.6-0.10.00.10.40.3-0.1-0.2-0.10.40.0
Distance traveled after self-admin0.91.13.01.7-1.4-1.71.6-0.4-0.50.41.50.40.41.11.2-0.50.81.1-1.2-1.2-0.6-1.01.00.70.80.60.0
Extensor digitorum longus weight0.52.06.5-0.92.60.10.0-2.3-2.3-2.00.31.61.61.31.32.01.40.9-0.9-0.7-1.5-1.40.91.11.11.60.0
Bone: elastic displacement0.30.40.60.00.4-0.30.3-0.3-0.4-0.70.50.80.80.70.70.80.70.7-0.7-0.7-0.8-0.80.70.80.70.70.0
Bone: elastic work1.01.32.71.6-0.7-1.61.6-1.3-1.20.01.50.80.91.41.4-0.21.21.3-1.3-1.2-0.9-1.11.10.81.00.80.0
Bone: endosteal estimation0.61.44.02.0-1.3-1.91.8-1.2-1.10.21.70.60.71.41.5-0.11.01.3-1.3-1.2-0.7-1.00.90.60.80.70.0
Bone: endosteal perimeter0.30.73.71.9-1.6-1.51.4-0.5-0.60.81.2-0.2-0.00.80.8-0.50.40.7-0.7-0.6-0.1-0.40.3-0.00.10.10.0
Epididymis fat weight0.00.10.4-0.30.4-0.20.2-0.6-0.60.20.10.10.00.40.4-0.40.30.2-0.2-0.2-0.2-0.40.20.20.20.00.0
Delta time in closed arm before/after self-admin0.50.51.10.8-0.5-1.11.0-1.0-1.00.20.80.50.50.70.9-0.70.70.7-0.7-0.7-0.4-0.40.50.20.50.20.0
Delta time in open arm before/after self-admin0.20.21.5-1.20.50.6-0.60.50.5-0.6-0.40.50.4-0.3-0.50.40.10.1-0.1-0.1-0.2-0.00.30.60.2-0.20.0
Diff in mean of infusions in LGA sessions0.91.12.5-0.0-0.11.0-1.00.80.40.1-1.2-1.1-1.0-1.2-1.10.5-1.4-1.41.61.61.11.0-1.5-1.3-1.4-0.60.0
Delay discount exponential model param0.40.51.6-1.01.20.3-0.2-0.2-0.4-1.00.10.70.50.30.31.30.60.6-0.6-0.7-0.8-0.60.81.00.50.8-0.4
Extinction: sum of active levers before priming3.94.37.22.2-0.2-2.42.5-2.6-2.6-0.72.51.61.72.52.70.52.12.2-2.2-2.3-1.9-2.32.22.01.92.00.0
Active lever presses in extinction session 65.85.89.71.70.9-1.92.1-2.5-2.3-2.02.52.42.52.72.62.12.52.6-2.7-2.7-2.7-2.82.82.82.73.10.0
Bone: final force0.71.23.11.8-0.9-1.71.7-1.5-1.30.31.40.80.91.11.2-0.91.11.1-1.1-1.0-0.7-0.90.80.50.90.50.0
Bone: final moment1.11.74.22.0-0.9-2.02.0-1.8-1.60.31.81.01.01.41.5-0.71.41.4-1.4-1.3-1.0-1.11.10.71.10.70.0
Food consumed during 24 hour testing period0.71.03.61.0-1.8-0.40.31.01.01.90.0-1.2-1.0-0.3-0.3-1.7-0.8-0.60.60.61.10.7-0.8-1.1-1.0-1.20.0
Glucose0.50.81.7-0.71.30.10.0-0.2-0.1-1.20.41.00.90.70.81.00.91.0-1.0-0.9-1.2-1.11.11.31.31.30.0
Heart weight0.30.51.40.1-0.90.1-0.10.80.90.8-0.4-0.6-0.6-0.6-0.6-1.2-0.6-0.60.60.70.70.7-0.7-0.8-0.7-0.80.0
Delay discount hyperbolic model param0.50.51.3-0.91.10.2-0.1-0.3-0.4-1.00.20.80.60.40.31.20.70.7-0.7-0.8-0.9-0.60.91.00.60.9-0.5
Intermittent access intake day 1-15 change0.61.12.81.0-0.7-1.71.6-1.7-1.60.31.30.80.61.41.4-1.11.21.1-1.2-1.0-0.8-0.90.70.30.70.20.0
Intermittent access intake escalation0.61.33.00.7-0.3-1.61.5-1.7-1.7-0.01.31.10.81.61.6-0.61.41.3-1.4-1.2-1.0-1.11.00.60.90.50.0
Intermittent access intake escalation 21.21.42.21.2-0.2-1.41.4-1.4-1.4-0.51.51.11.11.51.5-0.11.31.4-1.4-1.4-1.2-1.21.20.91.21.00.0
Intermitt. access day 1 inactive lever presses0.41.58.62.9-2.9-1.61.5-0.1-0.11.91.0-0.8-0.4-0.2-0.1-2.3-0.4-0.30.20.10.90.6-0.4-0.8-0.7-1.00.0
Intermitt. access day 15 inactive lever presses1.02.16.91.2-2.3-0.30.10.80.71.9-0.6-1.4-1.3-1.3-1.3-2.6-1.3-1.31.41.41.71.6-1.7-1.9-1.5-2.00.0
Intermitt. access escalation Index0.81.22.2-0.1-0.70.6-0.71.41.41.1-0.8-1.4-1.5-1.3-1.3-0.7-1.2-1.01.01.01.21.3-1.1-1.2-1.1-1.10.0
Intermittent access day 1 total infusions3.45.410.1-1.3-0.62.1-2.23.23.21.7-2.3-2.9-3.0-2.5-2.4-0.5-2.7-2.62.52.52.52.4-2.4-2.3-2.4-2.10.0
Intermittent access day 15 total infusions0.81.23.1-0.1-0.90.4-0.51.21.31.3-0.8-1.6-1.8-0.9-0.9-0.8-1.1-1.11.01.11.31.1-1.3-1.4-1.2-1.30.0
Intermittent access terminal intake (last 3 days)2.02.75.2-0.3-1.11.0-1.12.12.01.5-1.3-2.2-2.3-1.6-1.5-0.9-1.9-1.81.71.71.91.7-1.9-2.0-1.8-1.70.0
Intermittent access total infusions2.42.95.7-0.6-0.91.2-1.32.22.21.5-1.5-2.3-2.4-1.6-1.6-0.7-1.9-1.91.81.81.91.7-1.9-1.9-1.8-1.70.0
Intermittent access day 1 locomotion5.46.911.5-0.5-1.61.8-2.03.43.42.3-2.3-3.4-3.3-2.8-2.7-1.2-3.1-3.02.92.93.02.8-2.9-2.8-3.0-2.60.0
Intermittent access day 15 total locomotion1.22.24.40.0-1.50.5-0.61.71.61.8-1.0-2.0-2.1-1.3-1.2-1.0-1.7-1.51.51.51.71.5-1.7-1.8-1.8-1.60.0
Intermittent access total locomotion2.83.45.7-0.8-0.61.6-1.62.42.31.4-1.8-2.3-2.3-1.9-1.8-0.3-2.2-2.12.12.12.01.9-2.1-2.0-2.1-1.70.0
Intermittent access standard deviation0.51.15.62.4-2.3-1.81.7-0.5-0.51.51.1-0.6-0.50.30.4-1.80.20.4-0.4-0.30.30.1-0.1-0.5-0.1-0.40.0
Left kidney weight1.25.811.82.3-1.2-3.43.3-2.8-2.60.63.11.91.92.93.0-1.02.83.0-2.9-2.8-2.0-2.42.41.92.21.30.0
Right kidney weight2.09.215.53.0-0.9-3.93.9-3.4-3.30.03.92.52.53.83.9-0.13.43.6-3.7-3.6-2.7-3.23.22.63.02.20.0
Cocaine induced anxiety0.10.10.60.10.4-0.10.1-0.7-0.8-0.50.20.40.50.30.20.30.30.2-0.1-0.2-0.3-0.30.20.30.30.40.0
Post-drug Anxiety0.20.20.60.40.10.4-0.4-0.2-0.2-0.1-0.4-0.3-0.1-0.7-0.8-0.3-0.5-0.50.60.50.50.6-0.5-0.4-0.4-0.20.0
Baseline Anxiety1.11.32.70.3-1.10.4-0.51.21.21.2-0.8-1.2-1.1-1.3-1.3-1.6-1.2-1.11.11.11.31.4-1.2-1.2-1.1-1.40.0
Tail length2.07.920.24.2-2.7-4.54.4-2.9-2.91.63.91.51.73.33.4-1.62.73.1-3.0-3.0-1.9-2.62.41.62.11.50.0
Length with tail2.812.231.25.0-3.5-5.65.5-3.4-3.51.74.82.12.34.04.0-2.33.43.9-3.8-3.8-2.4-3.13.12.22.71.80.0
Length without tail1.54.711.22.4-1.7-3.43.3-2.4-2.20.92.91.61.52.62.6-1.52.32.6-2.5-2.5-1.7-2.02.01.51.91.10.0
Times rat made contact with spout0.70.82.8-1.11.70.2-0.1-0.7-0.6-1.10.30.90.70.80.70.41.00.9-0.9-0.9-1.1-1.01.01.11.11.00.0
Lifetime Intake1.51.84.0-0.8-0.41.2-1.22.01.91.0-1.3-1.8-1.9-1.3-1.2-0.2-1.5-1.51.41.41.41.2-1.4-1.4-1.3-1.20.0
Liver weight, left0.10.21.4-1.20.90.8-0.70.20.5-0.7-0.60.20.1-0.4-0.40.3-0.1-0.10.20.2-0.10.2-0.00.10.10.00.0
Liver weight, right0.20.31.2-0.71.00.5-0.4-0.00.0-0.7-0.10.70.70.40.21.10.30.3-0.3-0.2-0.6-0.60.50.70.50.70.0
Locomotor activity1.21.95.6-0.71.70.2-0.0-0.4-0.6-2.30.51.71.71.01.02.41.21.2-1.2-1.2-1.6-1.41.61.91.51.80.0
Locomotor testing distance0.51.04.6-1.01.50.5-0.40.1-0.1-1.80.11.00.90.50.62.10.70.6-0.7-0.8-1.1-0.91.01.31.01.20.0
Locomotor testing rearing0.30.74.9-2.21.61.4-1.41.00.8-0.9-0.90.1-0.2-0.3-0.31.3-0.2-0.30.30.2-0.10.20.00.20.0-0.00.0
Locomotion in novel chamber0.30.43.10.40.80.2-0.1-0.7-0.7-1.10.00.50.60.20.21.80.10.1-0.1-0.0-0.5-0.40.20.40.31.10.0
Locomotion in novel chamber post-restriction0.10.21.31.20.00.1-0.0-0.0-0.1-0.60.1-0.30.0-0.1-0.31.0-0.4-0.20.20.20.10.2-0.1-0.10.20.70.0
Fecal boli incidents, locomotor time 10.81.14.4-1.01.51.7-1.50.80.9-1.1-1.3-0.1-0.0-1.0-0.71.9-0.9-1.11.11.00.10.3-0.6-0.2-0.40.5-2.1
Change in fecal boli incidents, locomotor task1.81.73.8-0.11.2-0.50.6-1.5-1.5-1.70.81.91.91.31.21.11.51.3-1.3-1.2-1.6-1.51.41.50.91.5-0.3
Time >=10cm from walls, locomotor time 10.10.10.6-0.10.30.1-0.1-0.1-0.2-0.4-0.10.30.3-0.3-0.5-0.80.1-0.10.10.1-0.10.2-0.00.10.1-0.0-0.5
Bouts of movement, locomotor time 11.51.74.01.2-2.0-0.20.11.21.12.0-0.3-2.0-1.9-1.2-1.0-1.8-1.4-0.90.91.01.51.3-1.2-1.5-0.9-1.21.2
Total resting periods, locomotor time 11.11.33.21.4-1.7-0.20.11.11.01.6-0.2-1.8-1.6-1.0-0.8-1.2-1.2-0.90.90.91.31.1-1.1-1.3-0.9-0.91.0
Rest time, locomotor task time 10.81.03.4-0.51.01.4-1.30.50.6-0.9-1.2-0.5-0.4-1.3-1.01.1-1.1-1.21.21.20.50.8-0.9-0.6-0.40.3-1.8
Distance moved, locomotor task time 10.10.11.0-0.4-0.3-0.20.10.20.10.50.0-0.3-0.30.50.3-0.00.10.0-0.0-0.00.2-0.2-0.1-0.2-0.3-0.51.0
Vertical activity count, locomotor time 10.40.96.30.7-1.7-1.31.10.0-0.21.30.80.00.00.80.6-1.60.40.7-0.7-0.60.1-0.40.3-0.0-0.3-0.72.5
Time >=10cm from walls, locomotor time 20.71.02.0-0.90.61.4-1.41.31.3-0.1-1.3-0.7-0.6-1.2-1.10.5-1.1-1.31.31.30.80.8-1.1-0.8-0.9-0.4-0.8
Bouts of movement, locomotor time 20.10.10.60.2-0.40.0-0.10.70.60.70.1-0.6-0.6-0.1-0.2-0.4-0.3-0.00.0-0.00.30.00.0-0.0-0.3-0.20.7
Total resting periods, locomotor time 20.10.10.70.0-0.30.2-0.20.80.70.4-0.0-0.4-0.4-0.2-0.3-0.1-0.3-0.10.10.00.2-0.00.00.1-0.2-0.10.3
Rest time, locomotor task time 20.20.20.7-0.30.40.7-0.60.50.5-0.6-0.60.10.1-0.6-0.60.3-0.4-0.50.50.5-0.00.2-0.3-0.1-0.20.3-0.8
Distance moved, locomotor task time 20.30.30.9-0.8-0.20.3-0.40.60.70.8-0.5-0.8-0.8-0.2-0.2-0.2-0.4-0.50.50.50.70.4-0.6-0.7-0.5-0.90.5
Vertical activity count, locomotor time 20.30.41.80.5-1.3-0.70.60.20.21.40.3-0.6-0.50.10.2-1.2-0.10.1-0.1-0.00.60.2-0.2-0.5-0.3-0.81.4
Light reinforcement 10.30.61.8-0.8-0.50.6-0.61.41.30.9-0.7-0.7-0.8-0.7-0.7-0.8-0.7-0.70.70.70.80.7-0.7-0.6-0.9-1.10.0
Light reinforcement 20.71.13.5-1.91.41.8-1.70.70.8-0.3-1.6-0.3-0.4-1.2-1.10.5-0.9-1.11.11.10.50.8-0.8-0.4-0.8-0.50.0
Bone: marrow area0.71.54.22.0-1.2-1.91.9-1.2-1.20.01.80.70.81.51.5-0.01.11.4-1.4-1.3-0.8-1.11.10.70.90.80.0
Bone: maximum diameter0.61.12.81.7-0.9-1.61.6-1.4-1.30.01.40.70.81.31.3-0.31.01.1-1.1-1.0-0.7-0.90.80.40.70.60.0
Bone: maximum force1.11.95.32.3-1.3-2.22.2-1.7-1.60.71.90.70.91.41.5-1.21.31.4-1.4-1.3-0.8-1.11.00.61.00.50.0
Bone: maximum moment1.42.46.32.5-1.4-2.52.4-1.9-1.70.72.10.91.01.71.7-1.01.51.6-1.6-1.5-1.0-1.21.20.71.20.70.0
Mean time between licks in bursts0.20.61.30.1-0.90.2-0.30.60.51.1-0.5-0.7-0.7-0.7-0.7-0.6-0.8-0.90.80.80.90.9-0.9-1.0-1.0-1.10.0
Mean num. licks in bursts2.74.36.51.40.7-1.92.0-2.5-2.6-1.12.22.12.12.52.40.92.32.3-2.3-2.3-2.2-2.32.32.22.22.20.0
Cd content in liver0.10.10.4-0.60.60.2-0.2-0.3-0.4-0.4-0.20.20.00.10.10.10.1-0.10.10.1-0.1-0.0-0.1-0.1-0.10.00.0
Co content in liver0.30.31.5-0.81.10.5-0.4-0.6-0.6-1.2-0.20.80.70.20.21.00.30.0-0.0-0.1-0.5-0.30.30.50.30.50.0
Cu content in liver0.40.51.31.0-0.7-1.11.1-0.9-1.00.51.00.30.30.91.0-0.30.60.7-0.7-0.7-0.4-0.60.50.30.40.20.0
Fe content in liver0.10.10.8-0.50.60.6-0.60.20.2-0.6-0.40.10.2-0.00.00.9-0.2-0.30.30.3-0.00.0-0.10.0-0.10.10.0
K content in liver0.00.00.20.2-0.3-0.10.10.10.0-0.30.00.40.50.10.10.30.1-0.00.00.0-0.1-0.10.00.1-0.0-0.00.0
Mg content in liver0.60.62.1-0.61.10.4-0.3-0.4-0.4-1.4-0.11.31.30.40.41.50.60.3-0.3-0.3-0.9-0.70.60.90.60.80.0
Mn content in liver1.01.14.1-0.61.50.4-0.2-0.6-0.5-2.00.21.51.50.60.71.90.80.6-0.7-0.7-1.2-1.01.01.31.01.40.0
Na content in liver0.20.21.10.9-1.0-0.80.80.30.20.10.60.10.10.30.3-0.40.30.4-0.4-0.3-0.1-0.20.20.00.2-0.10.0
Rb content in liver0.40.51.0-0.20.00.6-0.6-0.10.1-0.0-0.8-0.5-0.5-0.8-0.7-0.2-0.7-1.01.00.90.70.9-0.9-0.9-1.0-0.70.0
Se content in liver1.31.68.4-2.52.92.1-1.90.10.1-1.9-1.31.00.9-0.3-0.22.3-0.1-0.40.40.4-0.6-0.30.10.70.30.80.0
Sr content in liver0.30.31.6-0.40.60.2-0.10.0-0.0-1.30.00.70.70.30.31.00.40.3-0.3-0.3-0.6-0.50.40.60.50.70.0
Zn content in liver0.70.73.6-1.91.91.3-1.2-0.3-0.3-1.5-1.00.90.9-0.2-0.11.30.1-0.40.40.4-0.4-0.2-0.00.40.10.30.0
Bone: minimum diameter0.71.47.22.7-2.7-2.01.9-0.4-0.41.71.5-0.5-0.30.80.8-1.40.20.7-0.6-0.60.3-0.10.1-0.4-0.1-0.40.0
Time in familiar zone, hab. session 12.92.85.90.51.2-1.21.3-2.4-2.2-1.41.51.81.72.01.91.31.91.7-1.7-1.8-1.8-2.01.81.71.71.80.0
Time in novel zone, hab. session 13.43.46.4-1.1-0.71.7-1.82.52.41.2-2.0-1.8-1.7-1.7-1.8-1.0-2.1-2.22.22.22.01.7-2.1-2.0-2.1-2.00.0
Total zone transitions, hab. session 10.40.61.70.1-0.60.3-0.40.71.11.3-0.4-1.3-1.3-0.6-0.7-0.5-1.0-0.60.60.51.00.8-0.7-0.8-0.8-0.70.0
Total locomotion distance, hab. session 10.30.53.01.7-1.7-0.90.90.70.80.90.8-0.5-0.3-0.0-0.0-0.6-0.20.3-0.3-0.40.20.10.20.00.1-0.00.0
Locomotion velocity, hab. session 10.20.31.91.4-1.2-0.80.80.40.50.40.9-0.10.00.20.1-0.00.10.6-0.6-0.7-0.1-0.20.60.40.50.40.0
Time in familiar zone, hab. session 22.32.44.21.7-0.1-1.61.7-1.9-1.9-1.51.71.92.01.61.60.71.61.5-1.4-1.5-1.6-1.61.51.51.41.60.0
Time in novel zone, hab. session 20.80.81.8-1.30.41.1-1.21.31.20.8-1.1-1.0-1.1-0.8-0.8-0.2-0.9-0.80.80.80.80.8-0.8-0.7-0.7-0.80.0
Total zone transitions, hab. session 22.22.85.3-2.00.72.2-2.22.12.31.0-2.1-1.6-1.6-1.9-1.90.2-1.9-1.81.81.81.51.6-1.7-1.4-1.6-1.30.0
Total locomotion distance, hab. session 21.11.53.2-0.2-1.00.8-0.81.81.71.1-1.0-1.4-1.3-1.4-1.4-0.8-1.4-1.21.21.21.31.3-1.2-1.2-1.2-1.10.0
Locomotion velocity, hab. session 20.81.02.5-0.3-0.70.8-0.81.61.50.8-0.9-1.1-1.1-1.2-1.2-0.5-1.2-1.01.11.01.11.1-1.0-1.0-1.0-0.90.0
Novel to familiar place preference ratio0.10.10.60.2-0.6-0.20.10.10.00.3-0.0-0.2-0.2-0.3-0.3-0.8-0.1-0.00.10.10.30.5-0.2-0.3-0.2-0.60.0
Novelty place preference0.10.10.60.0-0.6-0.1-0.00.30.20.3-0.1-0.3-0.3-0.4-0.3-0.8-0.3-0.20.20.20.50.5-0.3-0.5-0.3-0.70.0
Time in novel zone, NPP test0.20.20.6-0.2-0.50.1-0.20.50.40.4-0.3-0.5-0.5-0.6-0.5-0.8-0.4-0.30.30.40.60.7-0.5-0.6-0.4-0.80.0
Total zone transitions, NPP test0.10.11.4-0.20.10.2-0.20.30.61.20.0-0.6-0.6-0.1-0.10.2-0.30.1-0.1-0.10.20.10.10.1-0.10.10.0
Total locomotion distance, NPP test1.11.64.32.1-1.4-1.91.9-0.5-0.70.81.90.40.51.21.2-0.31.01.6-1.6-1.6-0.8-1.01.41.11.20.90.0
Locomotion velocity, NPP test1.21.74.82.2-1.4-1.91.9-0.6-0.80.61.90.50.71.41.4-0.21.11.5-1.5-1.6-0.9-1.21.51.21.21.00.0
Intraocular pressure0.20.30.70.1-0.30.3-0.40.10.20.1-0.4-0.8-0.9-0.7-0.7-0.3-0.7-0.60.60.60.70.8-0.6-0.6-0.7-0.50.0
Delta distance traveled before/after self-admin1.11.12.50.7-0.9-1.61.5-1.0-0.90.41.31.11.01.21.2-1.51.31.2-1.2-1.3-0.8-1.01.10.80.90.10.0
Delta ambulatory time before/after self-admin0.70.92.70.6-1.2-1.51.4-0.7-0.70.61.10.80.71.11.0-1.71.01.0-1.0-1.0-0.6-0.80.80.50.6-0.20.0
Parametrial fat weight2.04.810.6-0.92.6-0.40.6-2.5-2.3-2.91.13.33.12.01.92.02.42.0-2.0-2.0-2.8-2.32.32.52.52.50.0
Pavlov. Cond. lever latency0.50.62.00.10.7-0.50.6-1.4-1.4-0.70.60.80.71.11.10.50.90.6-0.7-0.6-0.8-0.90.50.50.60.70.0
Pavlov. Cond. magazine entry latency0.40.54.0-0.90.20.9-0.92.01.60.1-0.6-0.4-0.4-0.6-0.60.2-0.5-0.40.30.20.20.1-0.10.1-0.1-0.10.0
Pavlov. Cond. change in total contacts2.22.36.2-0.5-1.11.1-1.22.52.31.6-1.2-1.8-1.7-1.7-1.7-1.1-1.7-1.51.51.31.61.5-1.3-1.3-1.5-1.60.0
Pavlov. Cond. index score0.50.63.8-0.7-0.20.9-0.92.01.60.4-0.7-0.6-0.6-0.9-0.9-0.2-0.8-0.60.60.50.50.5-0.3-0.2-0.4-0.50.0
Pavlov. Cond. latency score0.60.73.7-0.4-0.50.8-0.81.91.70.7-0.7-0.8-0.8-1.0-1.0-0.3-0.9-0.70.70.60.70.7-0.5-0.4-0.6-0.70.0
Pavlov. Cond. lever contacts0.30.41.60.3-0.90.2-0.21.31.20.6-0.3-0.6-0.5-0.9-0.9-0.5-0.6-0.40.50.40.60.7-0.4-0.3-0.5-0.60.0
Pavlov. Cond. magazine entry number0.50.74.40.80.2-0.90.9-2.1-1.6-0.50.70.70.80.90.90.40.80.6-0.6-0.5-0.6-0.50.30.20.40.50.0
Pavlov. Cond. intertrial magazine entries0.20.30.8-0.90.90.8-0.8-0.1-0.0-0.3-0.8-0.3-0.3-0.6-0.60.8-0.5-0.40.50.60.20.5-0.4-0.3-0.40.10.0
Pavlov. Cond. lever-magazine prob. diff.0.70.84.7-0.9-0.11.1-1.12.21.80.5-0.9-0.7-0.7-1.1-1.1-0.2-0.9-0.80.80.70.60.6-0.5-0.3-0.5-0.60.0
Pavlov. Cond. response bias0.20.21.8-0.60.20.5-0.51.30.9-0.2-0.20.10.1-0.2-0.20.3-0.00.1-0.1-0.2-0.2-0.20.40.50.30.30.0
Pavlov. Cond. lever latency1.41.97.5-2.72.42.3-2.20.91.0-1.5-1.9-0.1-0.3-1.0-1.12.4-0.8-1.11.21.10.20.5-0.7-0.3-0.50.10.0
Pavlov. Cond. magazine entry latency0.91.15.32.3-1.9-1.81.8-0.4-0.60.51.50.20.40.80.8-1.30.60.9-0.9-0.9-0.3-0.50.70.40.50.20.0
Pavlov. Cond. change in total contacts1.82.812.53.5-3.2-3.02.8-1.1-1.31.62.3-0.10.11.11.2-2.80.91.3-1.3-1.3-0.1-0.40.70.00.5-0.30.0
Pavlov. Cond. index score1.62.28.83.0-2.5-2.62.4-0.9-1.11.12.10.20.41.31.3-2.21.01.4-1.4-1.4-0.4-0.71.00.50.80.20.0
Pavlov. Cond. latency score1.31.87.92.8-2.5-2.32.2-0.6-0.81.11.90.10.31.01.0-2.20.81.1-1.1-1.1-0.2-0.50.70.30.5-0.00.0
Pavlov. Cond. lever contacts1.52.08.12.8-2.5-2.42.3-1.0-1.21.51.90.00.21.11.1-2.50.81.2-1.2-1.2-0.2-0.50.70.20.5-0.10.0
Pavlov. Cond. magazine entry number1.41.85.3-2.31.82.2-2.11.01.2-0.7-1.9-0.4-0.5-1.3-1.31.6-1.1-1.41.41.50.60.9-1.1-0.7-0.9-0.40.0
Pavlov. Cond. intertrial magazine entries0.30.52.0-1.41.01.1-1.10.20.3-0.5-1.0-0.1-0.2-0.6-0.60.9-0.5-0.70.70.70.40.5-0.6-0.4-0.5-0.40.0
Pavlov. Cond. lever-magazine prob. diff.1.62.28.12.8-2.3-2.52.4-0.9-1.20.92.10.40.61.31.3-2.01.11.5-1.5-1.5-0.6-0.81.10.60.90.30.0
Pavlov. Cond. response bias1.72.39.13.0-2.7-2.62.5-1.0-1.21.82.1-0.10.11.11.1-2.80.81.2-1.3-1.2-0.1-0.50.70.20.5-0.20.0
Time in closed arm before self-admin1.92.44.2-1.20.21.7-1.71.81.90.9-1.7-1.8-1.7-1.9-2.0-0.7-1.7-1.71.61.61.61.8-1.6-1.4-1.4-1.50.0
Time in closed arm after self-admin1.11.22.61.1-0.90.3-0.30.40.51.2-0.5-1.6-1.4-1.3-1.2-0.9-1.3-1.21.11.11.41.5-1.3-1.4-1.1-0.90.0
Time in open arm before self-admin3.63.96.72.4-0.8-2.52.5-1.9-2.0-0.62.51.92.02.52.60.02.22.2-2.2-2.2-1.9-2.11.91.61.91.80.0
Time in open arm after self-admin1.61.83.50.1-0.1-1.31.3-0.8-0.9-0.81.31.91.71.71.60.11.71.7-1.6-1.6-1.6-1.61.61.61.50.90.0
Bone: periosteal estimation1.22.55.42.3-1.2-2.32.3-1.7-1.70.12.21.01.12.02.0-0.11.61.8-1.8-1.7-1.2-1.51.41.01.31.00.0
Bone: periosteal perimeter0.81.43.61.9-0.8-1.61.7-1.0-1.2-0.21.60.70.91.51.50.51.11.3-1.3-1.3-0.9-1.21.10.80.91.10.0
Bone: post-yield work0.60.95.01.9-2.2-1.31.2-0.00.01.80.7-0.9-0.70.10.1-1.6-0.30.00.00.10.70.4-0.4-0.8-0.5-0.80.0
Progressive ratio test 1 active lever presses1.21.53.20.2-1.30.4-0.51.71.61.6-0.7-1.8-1.8-1.0-1.0-0.8-1.3-1.21.11.11.41.1-1.3-1.4-1.2-1.20.0
Progressive ratio test 1 breakpoint1.31.63.50.3-1.40.3-0.41.71.71.6-0.7-1.9-1.9-1.0-1.1-0.9-1.4-1.21.11.21.51.2-1.3-1.5-1.3-1.30.0
Progressive ratio test 1 inactive lever presses3.95.79.60.7-2.60.6-0.82.32.43.1-1.5-3.1-3.0-2.5-2.4-2.4-2.7-2.42.52.32.92.7-2.6-2.7-2.6-2.80.0
Progressive ratio test 2 active lever presses0.30.41.3-0.20.10.5-0.50.90.80.5-0.5-1.1-1.1-0.4-0.40.6-0.6-0.60.50.70.60.4-0.7-0.7-0.5-0.20.0
Progressive ratio test 2 breakpoint0.40.51.5-0.40.10.6-0.61.11.00.5-0.6-1.1-1.2-0.5-0.50.6-0.7-0.70.60.80.60.5-0.8-0.8-0.6-0.30.0
Progressive ratio test 2 inactive lever presses2.33.77.41.4-2.10.3-0.41.31.42.5-1.0-2.7-2.5-1.8-1.8-1.5-2.2-2.12.02.12.42.2-2.3-2.5-2.3-1.90.0
Incentive Sensitization - Responses0.20.30.9-0.60.60.7-0.70.50.30.1-0.7-0.8-0.9-0.4-0.40.8-0.6-0.60.60.70.40.4-0.7-0.6-0.5-0.10.0
Incentive Sensitization - Breakpoint0.30.30.9-0.60.60.7-0.70.40.30.2-0.7-0.8-0.9-0.4-0.40.6-0.6-0.60.60.70.40.5-0.7-0.7-0.5-0.20.0
Sum of active levers in priming session hrs 5-60.10.10.50.00.40.1-0.0-0.3-0.4-0.3-0.10.00.00.10.20.70.0-0.10.10.1-0.2-0.2-0.1-0.1-0.20.40.0
Progressive ratio0.20.31.50.4-0.60.3-0.31.21.10.0-0.4-0.6-0.3-0.7-0.9-0.4-0.7-0.50.50.50.50.5-0.5-0.4-0.4-0.30.0
Food seeking constrained by brief footshock0.70.95.02.2-1.8-1.61.6-0.1-0.20.41.40.20.40.70.7-0.80.50.8-0.8-0.9-0.4-0.50.70.40.60.50.0
Seeking ratio, punishment vs. effort0.10.10.60.7-0.8-0.60.6-0.3-0.20.80.4-0.2-0.20.20.3-0.60.10.1-0.1-0.10.10.1-0.0-0.2-0.1-0.20.0
Retroperitoneal fat weight1.98.115.7-1.84.00.10.2-2.1-2.1-3.91.13.93.72.42.33.52.92.6-2.5-2.5-3.6-3.23.03.53.33.60.0
Reaction time number correct0.10.10.4-0.60.3-0.10.1-0.4-0.60.00.10.50.20.10.3-0.30.30.3-0.4-0.4-0.4-0.20.40.40.30.10.0
Reaction time mean minus median0.20.40.90.3-0.2-0.80.8-0.7-0.8-0.10.70.80.80.90.9-0.10.80.6-0.7-0.7-0.6-0.60.50.30.50.20.0
Reaction time mean minus median AUC0.41.02.00.3-0.2-1.31.2-1.3-1.3-0.31.11.31.21.41.3-0.41.41.1-1.2-1.1-1.0-1.10.90.70.90.40.0
Reaction time num false alarms0.40.61.9-1.40.61.1-1.10.70.7-0.4-1.1-0.4-0.6-0.9-0.9-0.1-0.6-0.90.90.80.60.8-0.7-0.6-0.7-0.80.0
Reaction time num false alarms AUC0.40.72.2-1.50.71.3-1.30.80.8-0.7-1.2-0.3-0.5-1.0-0.90.1-0.7-0.90.90.80.50.8-0.7-0.5-0.7-0.70.0
Reaction time trials correct on left0.10.10.4-0.60.3-0.10.1-0.4-0.60.00.10.50.20.10.3-0.30.30.3-0.4-0.4-0.4-0.20.40.40.30.10.0
Reaction time trials on left0.10.10.4-0.60.3-0.10.1-0.4-0.7-0.00.10.60.30.10.3-0.20.40.4-0.4-0.4-0.5-0.30.40.50.40.20.0
Reaction time mean0.10.10.5-0.1-0.3-0.50.4-0.1-0.20.40.30.20.00.60.5-0.70.40.2-0.3-0.3-0.2-0.40.2-0.00.1-0.30.0
Reaction time mean AUC0.10.10.4-0.1-0.1-0.40.3-0.1-0.20.10.30.30.20.60.5-0.50.50.3-0.3-0.3-0.3-0.40.20.10.1-0.20.0
Median of all reaction times0.00.10.4-0.4-0.2-0.0-0.00.40.30.4-0.1-0.2-0.30.20.0-0.70.0-0.10.00.00.1-0.1-0.1-0.2-0.2-0.40.0
Reaction time omissions0.50.71.9-0.70.8-0.30.3-0.8-0.7-0.90.41.41.20.90.90.81.10.8-0.8-0.8-1.1-0.90.90.90.90.60.0
Reaction time false alarm rate0.50.71.1-0.80.31.0-1.10.91.0-0.5-1.0-0.6-0.7-0.9-1.00.1-0.8-1.01.00.90.70.9-0.9-0.8-0.8-0.70.0
Reaction time premature initiation rate0.91.23.00.2-1.40.4-0.51.61.71.1-0.7-1.2-1.1-0.9-1.0-1.0-1.2-1.11.11.11.21.1-1.2-1.3-1.2-1.20.0
Reaction time premature initiations0.50.91.8-0.2-1.10.4-0.41.31.31.1-0.7-0.9-0.9-0.8-0.8-1.0-1.0-0.90.90.91.00.9-1.0-1.0-1.0-1.10.0
Std. dev. reaction times0.10.30.80.2-0.6-0.90.8-0.5-0.50.50.60.30.20.80.8-0.90.60.4-0.5-0.5-0.2-0.40.2-0.10.1-0.40.0
Reaction time trials completed0.10.10.4-0.60.3-0.10.1-0.4-0.7-0.00.10.60.30.10.3-0.20.40.4-0.4-0.4-0.5-0.30.40.50.40.20.0
Reaction time trials AUC0.20.30.8-0.70.7-0.10.1-0.7-0.9-0.40.20.90.60.40.60.20.70.6-0.6-0.6-0.8-0.60.70.70.60.50.0
Run reversals in cocaine runway, females0.20.21.60.2-1.0-0.70.6-0.3-0.21.00.2-0.3-0.40.30.2-1.30.10.1-0.10.00.30.1-0.2-0.5-0.3-0.80.0
Run reversals in cocaine runway, males4.34.39.2-0.72.1-0.50.7-2.0-2.0-2.61.23.03.01.81.91.62.42.0-2.0-2.1-2.6-2.42.42.62.52.30.0
Latency to leave start box in cocaine runway0.40.52.1-0.2-0.9-0.20.10.20.21.5-0.3-0.8-1.0-0.5-0.5-1.1-0.5-0.50.40.40.80.7-0.6-0.8-0.9-1.10.0
Latency to leave start box in cocaine runway, F0.80.92.5-0.6-0.80.3-0.40.50.61.4-0.7-0.9-1.1-0.8-0.8-1.5-0.8-0.90.80.81.11.1-1.0-1.1-1.1-1.60.0
Latency to leave start box in cocaine runway, M0.10.10.5-0.1-0.4-0.10.10.30.20.6-0.0-0.6-0.7-0.2-0.20.1-0.2-0.10.10.00.30.2-0.2-0.3-0.3-0.20.0
Std. dev. time between licks in bursts1.82.55.20.7-2.30.4-0.51.91.81.6-1.0-1.6-1.4-1.7-1.7-1.1-1.8-1.71.61.61.91.8-1.8-1.8-1.9-1.90.0
Total sessions with >9 infusions0.30.41.8-1.30.91.0-0.91.01.0-0.5-0.6-0.2-0.3-0.2-0.21.1-0.2-0.30.20.2-0.0-0.1-0.00.20.00.10.0
Short access day 1 total inactive lever presses4.05.310.41.0-2.70.3-0.51.91.93.2-1.2-3.1-3.0-2.2-2.2-2.4-2.5-2.22.22.32.82.6-2.6-2.9-2.6-2.70.0
Short access day 10 total inactive lever presses1.02.48.22.6-2.9-1.00.80.30.32.60.3-2.0-1.7-1.2-1.2-2.0-1.4-0.91.00.81.81.7-1.2-1.6-1.6-1.50.0
Short access day 1 total infusions0.20.30.8-0.2-0.40.3-0.40.90.90.6-0.5-0.7-0.7-0.5-0.5-0.0-0.5-0.60.60.60.60.5-0.7-0.7-0.6-0.60.0
Short access day 10 total infusions0.30.31.4-0.60.20.7-0.71.21.00.2-0.5-0.8-0.8-0.5-0.50.4-0.5-0.50.40.50.50.4-0.4-0.4-0.4-0.30.0
Short access total infusions0.30.41.6-1.00.50.9-0.91.31.1-0.1-0.7-0.6-0.7-0.4-0.40.8-0.5-0.60.50.50.30.2-0.4-0.3-0.3-0.20.0
Short access day 1 locomotion0.50.72.3-1.50.51.1-1.11.01.00.0-1.2-0.3-0.5-0.7-0.7-0.0-0.6-1.00.91.10.50.5-0.9-0.7-0.8-0.70.0
Short access day 10 total locomotion0.91.74.71.3-2.2-0.0-0.11.91.91.7-0.4-1.7-1.5-1.1-1.0-1.0-1.4-1.11.11.11.51.2-1.2-1.3-1.3-1.20.0
Short access total locomotion1.31.64.5-0.9-0.11.4-1.42.12.10.5-1.4-1.3-1.3-1.3-1.30.2-1.4-1.41.41.41.21.1-1.3-1.0-1.2-0.90.0
One hour access (0.3 mA shock)1.92.25.00.9-2.2-0.1-0.01.81.82.2-0.6-2.2-2.1-0.9-0.9-1.6-1.4-1.21.11.41.71.3-1.7-2.0-1.5-1.60.0
Compulsive drug intake1.11.32.1-0.1-1.30.4-0.51.31.21.4-0.9-1.2-1.2-1.3-1.3-1.3-1.3-1.01.11.11.41.4-1.3-1.4-1.2-1.50.0
One hour access (shock baseline)0.40.71.90.4-0.80.2-0.31.21.10.9-0.4-1.4-1.3-0.4-0.3-0.4-0.9-0.80.70.90.90.6-1.0-1.1-0.8-0.70.0
Social response proportion0.50.64.12.0-1.1-1.21.2-1.2-1.30.50.90.10.40.70.90.10.30.3-0.3-0.3-0.1-0.40.1-0.1-0.00.30.0
Social responses0.20.21.41.2-0.8-0.60.6-0.4-0.60.10.40.40.50.30.60.60.1-0.0-0.00.0-0.1-0.1-0.1-0.2-0.20.20.0
Social time0.60.84.01.9-2.0-1.51.4-0.4-0.71.40.9-0.4-0.40.30.4-1.20.10.2-0.2-0.20.40.2-0.2-0.6-0.5-0.50.0
Soleus weight0.10.30.7-0.50.90.1-0.0-0.6-0.5-0.90.00.70.70.50.40.70.50.3-0.4-0.2-0.6-0.50.30.40.50.50.0
Bone: stiffness0.50.82.71.6-0.9-1.51.4-1.5-1.30.61.20.30.40.80.8-1.00.70.8-0.8-0.8-0.3-0.50.60.30.60.20.0
Tibialis anterior weight0.82.75.7-0.62.3-0.40.5-2.4-2.3-2.10.82.01.81.71.71.91.81.5-1.4-1.2-1.9-1.71.41.51.71.90.0
Time to tail flick, vehicle, before self-admin0.40.40.9-0.7-0.00.6-0.70.90.90.4-0.7-0.6-0.6-0.8-0.9-0.7-0.5-0.50.50.60.50.8-0.6-0.6-0.6-0.70.0
Time to tail flick, vehicle, after self-admin0.10.22.61.6-0.7-0.40.50.10.2-0.00.5-0.20.10.00.00.5-0.10.1-0.1-0.1-0.0-0.00.0-0.00.10.70.0
Time to tail flick, test, before self-admin2.12.24.7-0.6-1.00.5-0.71.01.12.1-1.1-2.0-2.2-1.4-1.4-2.2-1.4-1.31.21.31.71.7-1.5-1.7-1.6-2.00.0
Time to tail flick, test, after self-admin0.10.10.20.00.10.3-0.30.20.2-0.0-0.2-0.3-0.2-0.3-0.40.1-0.3-0.30.30.20.20.2-0.2-0.0-0.30.10.0
Delta time to tail flick, vehicle, before/after SA0.20.21.51.2-0.9-0.70.8-0.2-0.10.20.70.20.30.40.5-0.00.20.4-0.4-0.4-0.2-0.30.40.30.30.30.0
Delta time to tail flick, test, before/after SA1.51.55.1-0.01.40.10.1-0.7-0.7-2.20.51.71.80.90.92.31.00.9-0.8-0.9-1.5-1.31.21.51.31.90.0
Tibia length1.13.07.32.5-1.5-2.72.6-2.1-1.81.32.40.70.82.02.1-1.61.61.9-1.9-1.9-1.0-1.41.51.01.30.70.0
Ambulatory time before self-admin0.20.31.81.3-0.8-0.20.20.60.40.50.2-1.0-0.7-0.3-0.20.6-0.7-0.30.20.30.50.4-0.3-0.4-0.30.20.0
Ambulatory time after self-admin1.21.45.52.3-2.1-2.12.0-0.5-0.71.01.70.10.21.11.2-1.20.71.0-1.1-1.1-0.3-0.80.80.50.60.20.0
Bone: tissue strength0.90.95.51.6-2.1-1.31.1-0.5-0.11.80.6-0.5-0.5-0.1-0.1-2.3-0.1-0.10.10.10.70.5-0.4-0.8-0.4-1.10.0
Total heroin consumption0.60.61.60.9-1.3-0.20.20.50.61.3-0.2-1.2-1.1-0.6-0.5-0.9-0.8-0.80.80.71.00.7-0.8-0.8-1.0-0.80.0
Bone: trabecular number0.50.82.11.3-0.9-1.51.4-1.1-1.00.71.20.40.50.60.6-1.30.90.9-1.0-1.0-0.5-0.50.80.50.70.30.0
Bone: trabecular spacing0.50.61.20.6-0.2-0.70.8-0.2-0.3-1.00.81.01.10.80.80.80.90.9-0.9-0.8-0.9-0.90.90.90.90.90.0
Bone: trabecular thickness0.00.10.3-0.60.50.1-0.2-0.4-0.20.5-0.1-0.2-0.3-0.1-0.1-0.40.10.0-0.0-0.00.10.1-0.0-0.10.0-0.30.0
Bone: trabecular tissue density1.92.89.2-1.63.00.7-0.4-1.0-0.9-2.90.31.81.61.21.22.81.41.2-1.3-1.2-1.9-1.71.62.01.92.20.0
Water consumed over 24 hours0.40.61.00.7-0.1-0.90.9-0.8-0.70.21.00.50.61.01.0-0.30.81.0-0.9-0.9-0.7-0.90.80.70.80.60.0
Number of responses in last shaping day0.20.20.90.4-0.8-0.20.10.90.90.90.1-0.8-0.8-0.2-0.20.1-0.3-0.10.10.10.40.2-0.3-0.4-0.5-0.20.0