Aplp1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Aplp1 0.1 0.09 5.6e-04 0.03 0.03 0.03 0.02 6.3e-04 4.0e-04 3.2e-04 2.0e-03
2 Brain gene expression Aplp1 0.1 0.07 4.2e-04 0.02 0.04 0.03 0.03 3.9e-03 1.4e-04 9.6e-04 6.7e-04
3 Brain intron excision ratio chr1_85702116_85702903 0.04 0.03 4.5e-06 0.04 0.06 0.06 0.06 5.4e-05 2.2e-06 3.5e-06 6.8e-06
4 IL gene expression Aplp1 0.21 0.15 1.0e-03 0.01 0.07 0.01 0.03 2.0e-01 8.9e-03 2.0e-01 6.6e-02
5 Brain intron excision ratio chr1_85702977_85703506 0.04 0.03 6.7e-06 0.04 0.06 0.06 0.06 1.7e-04 5.7e-06 3.5e-06 6.6e-06
6 PL mRNA stability Aplp1 0.2 0.09 2.2e-10 0.09 0.09 0.08 0.09 1.0e-09 9.6e-10 1.9e-09 8.6e-10
7 PL intron excision ratio chr1_85698091_85698696 0.05 0.04 1.4e-03 0.02 0.03 0.01 0.02 4.7e-03 5.0e-04 9.1e-03 1.5e-03
8 PL isoform ratio NM_001399814.1 0.32 0.12 6.3e-11 0.07 0.1 0.08 0.08 2.7e-08 3.2e-11 1.5e-09 1.7e-09
9 PL intron excision ratio chr1_85698088_85698696 0.2 0.09 1.2e-08 0.06 0.08 0.08 0.07 4.5e-07 3.5e-09 1.0e-08 1.6e-08
10 NAcc isoform ratio NM_001399814.1 0.06 0.04 1.3e-03 0.03 0.03 0.03 0.03 9.2e-05 2.5e-04 1.9e-04 1.8e-04
11 LHb mRNA stability Aplp1 0.59 0.14 2.4e-10 0.44 0.39 0.41 0.42 1.2e-11 2.4e-10 6.7e-11 3.6e-11
12 Brain mRNA stability Aplp1 0.33 0.11 0.0e+00 0.22 0.21 0.21 0.22 5.0e-20 7.0e-19 1.3e-19 7.1e-20
13 BLA mRNA stability Aplp1 0.1 0.06 8.1e-03 0.06 0.03 0.01 0.04 5.9e-04 1.1e-02 7.5e-02 2.4e-03
14 pVTA mRNA stability Aplp1 0.18 0.09 7.5e-04 0.06 0.06 0.06 0.06 1.9e-03 9.4e-04 1.6e-03 1.2e-03
15 NAcc mRNA stability Aplp1 0.14 0.06 3.5e-10 0.07 0.09 0.08 0.09 1.1e-08 3.2e-10 5.6e-10 4.5e-10
16 NAcc intron excision ratio chr1_85698088_85698696 0.09 0.05 1.2e-05 0.05 0.05 0.05 0.05 4.1e-06 1.1e-06 1.8e-06 1.8e-06
17 BLA isoform ratio NM_001399814.1 0.17 0.09 1.4e-03 0 0.05 0.04 0.03 1.8e-01 1.6e-03 4.3e-03 8.8e-03
18 BLA intron excision ratio chr1_85698088_85698696 0.17 0.1 3.3e-03 -0 0.03 0.01 0.01 3.8e-01 8.9e-03 8.7e-02 8.6e-02
19 Brain isoform ratio NM_001399814.1 0.26 0.12 8.7e-08 0.07 0.07 0.06 0.08 4.9e-07 4.9e-07 1.4e-06 4.6e-08
20 Brain intron excision ratio chr1_85698088_85698696 0.23 0.11 1.9e-11 0.13 0.13 0.13 0.13 4.0e-12 1.8e-12 3.1e-12 3.0e-12
21 IL mRNA stability Aplp1 0.71 0.15 9.9e-09 0.16 0.17 0.25 0.23 1.5e-04 5.5e-05 1.0e-06 2.8e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density1.11.83.1-0.2-0.1-1.41.3-1.5-1.61.61.31.4-1.81.61.70.3-1.5-1.51.51.21.31.51.40.9
Area under the delay curve0.80.91.81.01.3-0.00.20.20.8-0.4-0.7-1.01.0-0.9-0.9-0.90.91.2-1.3-1.1-1.1-1.3-0.7-0.9
BMI with tail0.20.50.9-0.6-0.30.9-0.91.00.6-1.0-0.5-0.50.8-0.9-0.90.10.70.6-0.6-0.5-0.6-0.5-0.9-0.3
BMI without tail0.00.10.40.3-0.0-0.20.4-0.2-0.10.20.60.4-0.20.20.20.1-0.3-0.20.20.30.20.40.40.1
Body weight1.35.412.91.92.1-3.63.4-3.6-2.13.31.61.6-2.82.92.9-2.1-2.0-1.61.60.91.41.41.9-0.2
Weight adjusted by age0.20.20.7-0.7-0.2-0.40.2-0.8-0.60.20.50.7-0.50.50.5-0.3-0.3-0.40.5-0.00.10.3-0.10.2
Bone surface0.50.92.71.31.5-1.61.5-1.4-0.61.40.20.1-1.10.90.9-1.1-0.4-0.20.2-0.20.10.30.5-0.6
Bone volume0.71.23.10.91.1-1.81.6-1.7-1.01.70.50.6-1.51.31.3-0.7-0.9-0.70.70.30.60.70.9-0.0
Breakpoint value in progressive ratio session0.91.04.32.02.1-0.71.0-0.40.50.4-0.7-1.20.6-0.6-0.5-1.30.61.1-1.2-0.8-0.7-1.1-0.3-0.9
Number of licking bursts3.33.96.5-0.5-0.72.2-2.52.22.3-2.3-2.3-2.02.2-2.2-2.2-0.22.21.8-1.8-1.7-1.9-1.8-2.3-1.6
Context. condit. distance diff. score0.80.91.60.40.80.4-0.50.60.7-0.5-1.3-1.21.0-0.9-0.9-1.01.11.1-1.1-1.2-1.1-1.3-1.2-1.0
Locomotion velocity, session 10.70.82.2-1.1-1.40.4-0.40.0-0.40.20.40.7-0.60.50.51.5-0.8-1.01.11.21.21.00.71.2
Locomotion distance, session 10.40.51.61.21.1-0.60.4-0.50.40.5-0.9-0.80.0-0.00.0-1.20.40.5-0.5-0.7-0.4-0.6-0.3-1.0
Locomotion velocity, session 20.20.21.10.0-0.90.8-0.70.80.8-0.6-0.1-0.20.4-0.4-0.41.00.20.0-0.10.30.00.10.10.2
Locomotion distance, session 21.72.44.20.2-0.31.6-1.71.72.0-1.6-1.9-1.81.8-1.7-1.7-0.61.71.5-1.5-1.3-1.4-1.5-1.6-1.7
Locomotion velocity, session 30.10.10.5-0.2-0.50.5-0.60.60.7-0.5-0.4-0.20.3-0.3-0.30.10.40.2-0.2-0.2-0.3-0.2-0.3-0.4
Locomotion distance, session 32.42.67.52.72.7-1.00.9-0.31.30.2-1.4-1.60.7-0.6-0.6-2.51.31.8-1.8-2.0-1.8-1.7-1.1-2.1
Stereotopy head waving bouts, day 31.82.13.9-1.7-2.00.4-0.10.0-1.30.21.81.8-0.90.91.02.0-1.5-1.71.62.01.71.81.41.8
Stereotopy head waving duration, day 31.82.15.3-2.1-2.30.8-0.50.3-1.2-0.21.61.6-0.60.60.62.3-1.3-1.61.51.91.61.71.21.9
Locomotion velocity, session 70.70.82.31.21.2-0.30.10.00.7-0.0-1.0-1.00.5-0.5-0.4-1.50.80.9-0.9-1.1-0.9-1.0-0.8-1.3
Locomotion distance, session 70.10.10.60.60.4-0.50.3-0.40.10.5-0.4-0.2-0.30.30.4-0.80.0-0.00.0-0.2-0.0-0.10.0-0.6
Stereotopy head waving bouts, day 71.51.72.90.2-0.21.4-1.41.41.7-1.5-1.5-1.41.6-1.5-1.5-0.31.51.3-1.3-1.1-1.3-1.2-1.4-1.3
Stereotopy head waving duration, day 71.01.33.2-1.0-1.11.8-1.71.71.0-1.6-0.8-0.81.4-1.3-1.30.81.00.7-0.7-0.4-0.6-0.7-1.1-0.3
Locomotion velocity, session 83.03.66.5-0.8-0.92.4-2.52.62.1-2.4-2.0-1.82.3-2.3-2.30.42.01.7-1.7-1.4-1.6-1.7-2.0-0.8
Locomotion distance, session 82.84.16.80.70.61.4-1.71.72.3-1.7-2.6-2.52.2-2.1-2.1-1.42.42.2-2.2-2.2-2.2-2.3-2.3-2.2
Degree of sensitization distance1.11.12.2-1.3-1.50.1-0.2-0.4-0.90.40.81.0-0.90.80.81.3-1.0-1.31.41.31.31.20.91.2
Degree of sensitization stereotypy2.72.94.60.30.01.6-1.71.72.2-1.8-1.9-1.92.0-1.9-1.9-0.62.01.8-1.8-1.7-1.8-1.8-1.9-1.7
Conditioned locomotion0.50.61.2-0.1-0.21.1-0.91.10.7-1.0-0.7-0.81.1-1.1-1.10.50.80.8-0.8-0.4-0.6-0.8-0.80.0
Cocaine response after cond. corrected1.51.73.1-1.3-1.2-0.10.4-0.3-1.30.51.81.7-1.11.01.01.6-1.4-1.51.41.61.41.61.31.8
Cocaine response after cond. not corrected2.93.25.3-1.4-1.5-0.50.7-0.6-1.70.92.32.2-1.71.61.62.1-2.0-2.12.02.22.02.22.02.3
Cocaine response before conditioning0.60.82.01.20.7-1.41.3-1.3-0.41.30.50.5-1.21.11.1-0.1-0.7-0.60.60.40.50.61.00.1
Saline control response0.30.40.7-0.2-0.4-0.20.3-0.3-0.60.40.60.6-0.60.60.60.6-0.7-0.70.70.80.80.80.70.8
Bone: connectivity density0.20.30.70.40.2-0.70.7-0.6-0.50.70.60.5-0.80.60.6-0.0-0.5-0.50.40.30.40.70.6-0.1
Bone: cortical apparent density1.01.33.0-1.0-0.91.6-1.71.61.1-1.4-1.2-1.01.3-1.3-1.30.21.10.8-0.8-0.6-0.7-0.8-1.3-0.4
Bone: cortical area0.71.12.30.70.7-1.51.5-1.5-1.11.51.00.9-1.21.31.3-0.1-1.0-0.80.80.60.80.71.10.5
Bone: cortical porosity3.03.37.00.5-0.11.8-1.82.02.6-2.2-1.7-1.82.2-2.0-2.0-0.02.11.9-2.0-1.8-2.1-1.7-1.8-1.7
Bone: cortical porosity3.94.28.50.5-0.12.0-2.02.22.9-2.4-2.0-2.12.4-2.2-2.2-0.12.42.2-2.2-2.0-2.3-2.0-2.1-1.9
Bone: cortical thickness0.50.91.3-0.1-0.1-0.90.9-0.9-1.01.01.11.0-1.11.11.10.4-1.1-1.01.01.01.01.01.10.7
Bone: cortical thickness0.50.51.9-1.2-1.40.6-0.60.3-0.5-0.30.50.7-0.10.30.31.4-0.5-0.70.70.90.80.60.41.0
Bone: cortical tissue density1.21.53.5-1.1-0.91.8-1.91.81.2-1.6-1.3-1.11.4-1.5-1.50.31.20.9-0.9-0.7-0.8-0.9-1.4-0.4
Condit. Reinf. active minus inactive responses0.10.10.3-0.4-0.30.5-0.40.50.2-0.5-0.1-0.10.6-0.4-0.30.50.20.2-0.2-0.0-0.1-0.3-0.20.1
Condit. Reinf. active-inactive response ratio0.90.92.2-1.3-1.10.20.1-0.1-1.1-0.01.51.3-0.40.50.51.5-1.0-1.00.91.20.90.90.91.4
Condit. Reinf. active responses1.41.73.7-0.7-0.81.8-1.81.91.2-1.7-1.2-1.21.7-1.6-1.60.51.21.1-1.1-0.7-0.9-1.1-1.3-0.5
Condit. Reinf. inactive responses3.23.86.10.2-0.12.0-2.12.42.3-2.1-2.5-2.32.2-2.3-2.3-0.42.22.0-2.0-1.6-1.7-1.9-2.2-1.7
Incentive salience index mean0.30.30.7-0.0-0.10.7-0.50.80.6-0.7-0.3-0.50.8-0.7-0.70.30.60.6-0.6-0.4-0.5-0.6-0.5-0.2
Condit. Reinf. lever presses0.40.61.10.80.60.4-0.20.71.0-0.7-0.6-0.80.9-0.8-0.8-0.10.81.0-1.1-0.9-1.0-0.9-0.6-0.6
Condit. Reinf. active minus inactive responses0.40.52.21.51.1-1.21.4-0.7-0.41.00.60.3-0.70.70.7-0.3-0.5-0.20.10.20.20.40.8-0.1
Condit. Reinf. active-inactive response ratio0.00.00.3-0.3-0.30.1-0.10.4-0.1-0.10.00.10.00.00.00.5-0.1-0.10.10.20.10.10.00.3
Condit. Reinf. active responses1.01.36.32.52.1-1.92.0-1.4-0.31.50.40.1-1.00.90.9-1.3-0.40.1-0.1-0.3-0.10.10.7-0.7
Condit. Reinf. inactive responses1.62.010.23.22.7-1.81.8-1.40.51.0-0.4-0.7-0.30.20.2-2.30.51.0-1.0-1.3-1.1-0.8-0.0-1.7
Condit. Reinf. lever presses2.83.810.42.52.3-3.13.2-2.7-1.72.81.41.1-2.22.22.2-1.4-1.6-1.00.90.61.01.11.90.0
Condit. Reinf. lever reinforcers received1.11.57.72.82.4-1.91.9-1.3-0.01.4-0.1-0.3-0.80.70.7-1.7-0.00.4-0.5-0.7-0.5-0.20.4-1.2
Conditioned reinforcement - actives0.10.10.60.2-0.30.4-0.50.50.8-0.3-0.7-0.50.2-0.2-0.20.10.40.2-0.2-0.2-0.2-0.0-0.2-0.6
Conditioned reinforcement - inactives4.04.57.32.52.30.2-0.31.02.3-1.1-2.2-2.51.9-1.9-1.9-2.12.32.6-2.6-2.7-2.6-2.4-2.0-2.4
Conditioned locomotion2.73.35.40.0-0.42.0-2.12.32.2-2.1-2.1-2.02.2-2.1-2.10.02.01.8-1.8-1.5-1.7-1.6-1.9-1.2
Patch foraging indifference point 0 sec0.10.10.70.80.5-0.10.20.20.5-0.20.0-0.20.2-0.3-0.3-0.30.30.5-0.5-0.5-0.6-0.3-0.1-0.3
Patch foraging indifference point AUC0.10.20.8-0.7-0.90.5-0.50.60.0-0.40.40.40.1-0.0-0.00.5-0.2-0.30.30.40.30.40.10.2
Delay disc. indifference point, 0s delay2.83.16.01.21.80.5-0.60.81.5-0.7-2.4-2.41.8-1.7-1.7-1.71.92.1-2.1-2.0-1.8-2.3-1.9-1.8
Delay disc. indifference point, 16s delay1.11.13.11.41.8-0.20.50.30.9-0.3-0.6-1.11.0-0.9-0.9-1.11.01.4-1.5-1.3-1.3-1.3-0.6-0.9
Delay disc. indifference point, 2s delay1.11.23.41.61.8-0.60.4-0.30.70.2-1.2-1.20.7-0.5-0.5-1.80.91.2-1.1-1.3-1.1-1.4-0.9-1.5
Delay disc. indifference point, 24s delay0.90.93.91.72.0-1.11.2-0.70.20.4-0.1-0.40.1-0.2-0.2-1.80.40.8-0.9-1.0-0.9-0.8-0.3-0.8
Delay disc. indifference point, 4s delay1.01.12.20.70.60.6-0.60.81.5-0.9-1.0-1.21.2-1.2-1.2-0.41.21.2-1.3-1.2-1.3-1.0-0.9-1.0
Delay disc. indifference point, 8s delay0.10.10.40.60.6-0.20.3-0.30.30.0-0.1-0.20.3-0.2-0.2-0.50.30.4-0.5-0.5-0.5-0.5-0.1-0.5
Indifference point function ln k0.10.20.60.70.7-0.70.7-0.8-0.40.70.00.0-0.30.50.5-0.4-0.3-0.10.10.20.30.00.30.0
Indifference point function log k0.10.20.60.70.7-0.70.7-0.8-0.40.70.00.0-0.30.50.5-0.4-0.3-0.10.10.20.30.00.30.0
Patch foraging total patch changes 0 sec0.10.21.11.00.7-0.30.40.10.5-0.1-0.1-0.30.1-0.2-0.2-0.50.40.5-0.6-0.6-0.7-0.3-0.1-0.4
Patch foraging total patch changes 12 sec0.10.10.50.1-0.30.10.20.30.1-0.10.70.3-0.10.10.10.5-0.3-0.20.10.40.20.40.60.1
Patch foraging total patch changes 18 sec0.40.50.90.50.30.2-0.40.51.0-0.5-0.8-0.70.5-0.6-0.6-0.60.80.7-0.7-0.9-0.9-0.6-0.8-0.8
Patch foraging total patch changes 24 sec0.60.82.51.31.5-0.70.5-0.40.60.3-0.8-0.80.1-0.2-0.2-1.60.70.9-0.8-1.2-1.0-0.9-0.7-1.2
Patch foraging total patch changes 6 sec0.00.00.30.4-0.1-0.10.20.20.2-0.20.50.4-0.2-0.0-0.00.1-0.00.0-0.1-0.1-0.30.30.10.1
Patch foraging time to switch 0 sec0.30.52.2-1.3-1.20.7-0.50.5-0.1-0.40.70.5-0.1-0.0-0.01.5-0.4-0.50.50.80.60.70.50.9
Patch foraging water rate 0 sec0.40.71.50.0-0.51.1-1.11.10.9-1.2-0.7-0.61.1-1.0-1.00.10.80.7-0.7-0.6-0.8-0.8-1.0-0.4
Patch foraging water rate 12 sec0.50.73.61.91.0-0.70.3-0.70.80.3-1.0-0.6-0.00.10.1-1.40.60.6-0.5-1.1-0.9-0.7-0.6-1.2
Patch foraging water rate 18 sec0.10.10.30.5-0.40.4-0.50.40.5-0.5-0.2-0.10.4-0.3-0.30.20.30.2-0.2-0.1-0.2-0.2-0.3-0.2
Patch foraging water rate 24 sec3.04.27.11.91.60.6-0.90.82.1-1.2-2.6-2.52.0-1.8-1.8-2.22.32.3-2.3-2.5-2.4-2.5-2.2-2.7
Patch foraging water rate 6 sec1.21.75.92.41.9-0.80.5-0.51.00.1-1.3-1.20.6-0.5-0.5-2.01.21.4-1.3-1.8-1.6-1.4-1.1-1.8
Seeking ratio, delayed vs. immediate footshock1.21.43.61.41.9-0.70.4-0.41.00.2-1.3-1.40.7-0.5-0.5-1.81.11.3-1.3-1.7-1.4-1.6-0.9-1.4
Distance traveled before self-admin0.10.10.30.30.0-0.10.1-0.20.10.5-0.4-0.4-0.40.30.40.1-0.1-0.20.20.40.50.30.5-0.1
Distance traveled after self-admin1.21.46.32.52.0-1.91.8-1.7-0.11.6-0.0-0.2-1.00.90.8-1.6-0.30.1-0.1-0.3-0.00.30.6-0.8
Extensor digitorum longus weight0.62.36.5-2.5-1.60.1-0.0-0.3-2.20.61.51.7-0.91.11.11.7-1.5-1.71.71.71.81.31.02.4
Bone: elastic displacement0.40.40.7-0.4-0.6-0.20.3-0.4-0.40.50.70.7-0.60.80.80.5-0.7-0.80.80.90.80.80.80.4
Bone: elastic work1.01.33.10.80.9-1.61.6-1.8-1.01.60.90.8-1.31.41.4-0.6-1.1-0.80.80.60.80.81.20.0
Bone: endosteal estimation0.51.03.21.71.6-1.81.8-1.7-0.71.50.40.3-1.01.01.0-0.7-0.6-0.20.3-0.00.30.10.8-0.0
Bone: endosteal perimeter0.40.83.51.81.9-1.51.5-1.3-0.21.1-0.1-0.3-0.40.50.5-1.0-0.10.3-0.3-0.5-0.3-0.50.3-0.4
Epididymis fat weight0.10.21.10.50.5-0.40.2-0.50.30.3-0.4-0.3-0.00.20.2-1.00.20.1-0.1-0.4-0.2-0.2-0.3-0.9
Delta time in closed arm before/after self-admin1.51.53.40.51.1-1.81.8-1.9-1.61.71.11.0-1.31.41.4-0.8-1.2-0.90.90.60.90.61.00.3
Delta time in open arm before/after self-admin0.30.31.3-0.4-1.10.7-0.80.70.5-0.90.30.50.0-0.1-0.10.80.1-0.10.20.0-0.20.5-0.20.1
Diff in mean of infusions in LGA sessions1.31.52.90.60.61.1-0.81.21.1-1.0-1.4-1.71.7-1.7-1.5-0.21.31.5-1.5-0.9-1.0-1.4-1.1-0.7
Delay discount exponential model param0.60.61.5-1.0-1.20.2-0.30.0-0.70.20.40.7-0.80.70.70.9-0.7-1.01.11.01.01.00.50.8
Extinction: sum of active levers before priming2.32.35.00.71.1-2.12.1-2.2-1.72.11.31.2-1.91.71.7-0.5-1.5-1.21.21.01.31.41.50.7
Active lever presses in extinction session 65.35.28.00.20.0-2.12.5-2.3-2.52.62.42.2-2.62.62.60.9-2.7-2.42.32.52.72.22.81.9
Bone: final force0.50.82.41.01.4-1.51.5-1.4-0.81.20.60.4-0.90.80.8-1.2-0.5-0.20.2-0.10.10.30.6-0.4
Bone: final moment0.71.23.31.01.5-1.81.8-1.6-1.01.60.80.6-1.11.11.1-1.3-0.8-0.40.40.10.40.40.8-0.3
Food consumed during 24 hour testing period1.01.23.61.91.6-0.50.4-0.40.90.0-1.1-1.20.5-0.5-0.5-1.51.01.2-1.2-1.3-1.2-1.2-0.7-1.6
Glucose0.40.61.3-0.9-1.10.0-0.1-0.3-0.50.40.50.8-0.70.80.70.9-0.8-1.11.11.11.11.00.80.8
Heart weight0.40.61.30.91.2-0.10.10.20.6-0.2-1.0-0.90.7-0.6-0.6-0.90.81.0-0.9-1.0-0.9-1.0-0.9-0.8
Delay discount hyperbolic model param0.70.71.5-1.0-1.20.1-0.2-0.1-0.70.30.60.9-0.90.80.80.9-0.8-1.11.11.11.11.10.70.9
Intermittent access intake day 1-15 change0.80.82.50.81.2-1.61.3-1.6-0.91.30.40.5-1.01.01.0-1.1-0.5-0.40.4-0.20.20.10.3-0.2
Intermittent access intake escalation0.70.72.20.91.4-1.51.2-1.5-0.71.10.10.3-0.70.70.7-1.3-0.3-0.10.2-0.4-0.1-0.20.0-0.4
Intermittent access intake escalation 20.80.81.90.60.8-1.41.3-1.4-1.01.20.70.7-1.01.11.1-0.5-0.8-0.60.60.30.50.40.80.1
Intermitt. access day 1 inactive lever presses0.90.93.71.61.9-1.61.9-1.2-0.81.01.00.5-0.60.60.6-1.0-0.50.1-0.2-0.2-0.20.10.6-0.1
Intermitt. access day 15 inactive lever presses1.01.12.21.01.5-0.10.20.40.7-0.5-0.5-0.91.1-1.1-1.1-1.01.01.4-1.4-1.4-1.4-1.4-0.9-0.9
Intermitt. access escalation Index0.90.81.90.30.50.5-0.70.81.0-0.6-1.4-1.30.9-0.9-0.9-0.71.01.0-1.0-1.0-0.9-1.1-1.0-0.9
Intermittent access day 1 total infusions4.65.39.10.40.12.1-2.42.42.9-2.3-3.0-2.82.6-2.6-2.6-0.62.72.4-2.4-2.3-2.3-2.3-2.5-2.0
Intermittent access day 15 total infusions3.64.17.41.31.40.7-1.11.12.3-1.2-2.7-2.61.9-1.9-1.9-1.72.42.3-2.3-2.5-2.4-2.4-2.2-2.3
Intermittent access terminal intake (last 3 days)3.94.37.61.31.11.1-1.41.52.5-1.5-2.8-2.72.1-2.1-2.1-1.32.52.4-2.4-2.4-2.4-2.4-2.2-2.2
Intermittent access total infusions4.14.68.81.20.91.3-1.61.72.7-1.7-3.0-2.82.2-2.2-2.2-1.22.62.4-2.4-2.4-2.4-2.3-2.3-2.2
Intermittent access day 1 locomotion5.45.78.91.20.91.7-1.82.23.0-2.1-2.9-2.92.7-2.7-2.7-1.12.82.7-2.7-2.5-2.6-2.6-2.5-2.1
Intermittent access day 15 total locomotion3.84.16.91.71.50.7-1.01.02.3-1.2-2.6-2.52.0-2.0-2.0-1.82.32.3-2.3-2.4-2.3-2.3-2.2-2.3
Intermittent access total locomotion3.54.06.50.80.31.6-1.82.02.6-1.9-2.4-2.42.3-2.3-2.3-0.72.32.2-2.2-2.0-2.1-2.0-2.1-1.8
Intermittent access standard deviation1.71.87.72.62.8-1.91.7-1.40.11.3-0.7-0.8-0.30.40.4-2.30.40.8-0.8-1.3-0.9-0.9-0.2-1.4
Left kidney weight2.67.414.70.30.8-3.43.2-3.8-3.23.42.72.8-3.53.53.4-0.8-2.9-2.62.71.92.32.52.61.1
Right kidney weight3.59.921.21.21.7-4.34.1-4.6-3.44.22.92.9-4.04.03.9-1.3-3.2-2.82.81.92.52.73.10.8
Cocaine induced anxiety0.40.51.10.20.4-0.80.9-0.6-1.00.80.90.7-0.80.70.7-0.0-0.8-0.50.50.60.60.60.80.5
Post-drug Anxiety0.20.20.9-0.7-0.40.20.10.4-0.6-0.11.00.6-0.10.00.00.8-0.4-0.30.20.60.40.40.50.8
Baseline Anxiety1.11.12.4-0.7-0.61.4-1.31.51.3-1.5-0.6-0.71.4-1.3-1.30.41.10.9-1.0-0.8-1.0-0.9-1.0-0.4
Tail length2.57.516.72.52.1-4.04.0-4.1-2.43.72.42.2-3.33.43.3-1.5-2.5-2.02.01.41.81.92.70.3
Length with tail3.312.231.63.93.8-5.65.4-5.5-2.95.02.22.1-4.04.24.2-3.3-2.8-2.02.01.01.71.72.9-0.6
Length without tail1.94.212.12.52.8-3.53.2-3.3-1.62.90.80.9-2.12.32.3-2.8-1.2-0.70.8-0.10.50.51.1-0.9
Times rat made contact with spout0.91.12.6-1.6-1.60.1-0.4-0.5-1.10.40.61.0-0.90.90.91.1-1.0-1.41.41.21.31.20.81.0
Lifetime Intake2.32.65.60.50.31.2-1.51.42.1-1.4-2.4-2.11.7-1.7-1.7-0.72.01.7-1.7-1.7-1.7-1.7-1.7-1.6
Liver weight, left0.71.12.8-1.7-1.60.3-0.30.1-0.90.01.31.3-0.70.80.81.3-1.0-1.31.21.31.21.20.81.2
Liver weight, right0.40.61.5-0.5-1.20.20.00.0-0.2-0.11.21.1-0.60.70.60.8-0.8-0.90.91.00.81.20.90.5
Locomotor activity1.42.24.5-1.3-2.00.20.0-0.1-1.00.41.61.6-1.31.21.21.9-1.6-1.81.72.11.92.11.61.6
Locomotor testing distance0.61.02.4-1.0-1.50.3-0.2-0.1-0.50.30.80.9-0.90.80.81.4-1.0-1.21.21.41.31.51.11.1
Locomotor testing rearing0.40.73.7-1.4-1.91.3-1.60.90.5-1.0-0.40.10.3-0.3-0.31.00.2-0.30.40.30.20.4-0.40.2
Locomotion in novel chamber0.20.21.0-0.3-0.50.4-0.00.5-0.4-0.20.60.30.2-0.0-0.11.0-0.4-0.30.20.80.60.40.60.7
Locomotion in novel chamber post-restriction0.10.10.40.20.20.00.30.2-0.30.20.2-0.20.0-0.2-0.20.5-0.2-0.0-0.10.50.40.10.60.5
Fecal boli incidents, locomotor time 10.60.72.5-1.0-1.31.5-1.01.30.4-1.10.1-0.00.8-0.9-0.91.60.0-0.0-0.10.80.40.20.10.7
Change in fecal boli incidents, locomotor task1.71.63.7-0.7-0.7-0.60.8-0.7-1.50.71.91.7-1.11.11.11.3-1.4-1.41.31.41.21.31.41.7
Time >=10cm from walls, locomotor time 10.10.10.3-0.6-0.30.1-0.10.4-0.3-0.20.40.4-0.0-0.0-0.00.4-0.1-0.20.10.10.00.20.10.4
Bouts of movement, locomotor time 11.71.83.81.91.8-0.20.10.01.3-0.1-1.8-1.90.9-0.9-0.9-1.81.31.6-1.6-1.5-1.3-1.5-1.1-1.8
Total resting periods, locomotor time 11.21.33.01.71.6-0.20.20.01.2-0.0-1.6-1.70.8-0.8-0.8-1.41.11.3-1.4-1.2-1.0-1.3-0.8-1.5
Rest time, locomotor task time 10.40.41.3-0.6-0.81.1-0.71.00.1-0.80.0-0.10.8-0.8-0.81.10.00.1-0.10.60.4-0.00.00.7
Distance moved, locomotor task time 10.10.10.40.00.2-0.3-0.1-0.40.10.2-0.5-0.30.00.00.0-0.60.20.1-0.0-0.5-0.3-0.4-0.4-0.5
Vertical activity count, locomotor time 10.60.72.51.61.3-1.31.1-1.2-0.00.80.10.1-0.60.60.6-1.40.10.2-0.2-0.8-0.6-0.2-0.1-0.8
Time >=10cm from walls, locomotor time 20.90.92.3-0.7-0.91.5-1.31.51.0-1.3-0.6-0.71.3-1.3-1.30.70.80.6-0.7-0.2-0.4-0.6-0.7-0.1
Bouts of movement, locomotor time 20.20.20.70.50.10.1-0.20.00.6-0.0-0.8-0.70.1-0.1-0.1-0.60.40.3-0.3-0.3-0.3-0.2-0.2-0.7
Total resting periods, locomotor time 20.10.10.40.5-0.10.2-0.30.20.6-0.2-0.5-0.40.1-0.1-0.1-0.20.30.2-0.2-0.1-0.2-0.1-0.1-0.5
Rest time, locomotor task time 20.20.20.9-0.1-0.70.8-0.40.80.3-0.60.20.10.5-0.5-0.50.9-0.00.0-0.10.40.20.00.10.5
Distance moved, locomotor task time 20.40.51.0-0.10.10.3-0.70.10.7-0.4-1.0-0.80.6-0.5-0.5-0.90.80.6-0.6-1.0-0.8-0.8-0.9-1.0
Vertical activity count, locomotor time 20.50.62.71.11.2-0.70.5-0.70.40.4-0.6-0.6-0.10.00.0-1.70.50.6-0.6-1.0-0.8-0.6-0.5-1.2
Light reinforcement 10.40.71.70.60.10.6-0.70.91.3-0.9-0.9-0.80.7-0.8-0.8-0.41.00.9-0.9-1.0-1.1-0.7-0.9-0.9
Light reinforcement 20.91.23.7-1.2-1.41.9-1.71.90.7-1.8-0.3-0.31.2-1.3-1.31.10.70.5-0.5-0.1-0.5-0.4-0.90.1
Bone: marrow area0.51.13.41.61.6-1.81.8-1.7-0.81.60.60.4-1.11.11.1-0.6-0.7-0.30.30.10.30.20.90.1
Bone: maximum diameter0.50.92.50.91.1-1.61.6-1.5-1.01.30.90.7-0.91.11.1-0.2-0.8-0.50.50.20.40.20.90.6
Bone: maximum force0.81.34.01.41.9-2.02.0-1.8-0.91.70.60.4-1.11.11.1-1.6-0.6-0.20.2-0.20.20.20.7-0.6
Bone: maximum moment1.01.74.91.42.0-2.22.2-2.0-1.01.90.70.5-1.31.31.3-1.7-0.8-0.40.3-0.00.30.40.8-0.5
Mean time between licks in bursts0.20.30.80.60.40.3-0.20.40.6-0.6-0.2-0.40.7-0.7-0.7-0.40.60.7-0.8-0.7-0.9-0.6-0.5-0.6
Mean num. licks in bursts3.74.46.5-0.5-0.3-1.81.9-2.1-2.52.22.22.2-2.42.42.40.8-2.4-2.32.32.22.42.22.31.9
Cd content in liver0.20.20.5-0.3-0.2-0.40.3-0.7-0.30.60.10.3-0.60.60.60.1-0.5-0.60.60.40.60.50.40.2
Co content in liver0.10.10.6-0.8-0.60.6-0.40.6-0.2-0.60.40.30.3-0.3-0.30.40.0-0.0-0.00.1-0.10.1-0.20.2
Cu content in liver0.10.10.50.50.7-0.70.6-0.7-0.30.50.10.1-0.30.30.3-0.5-0.10.00.0-0.3-0.1-0.10.00.2
Fe content in liver0.10.10.10.00.10.2-0.20.30.2-0.3-0.2-0.20.4-0.4-0.40.30.30.3-0.3-0.3-0.3-0.3-0.30.4
K content in liver0.10.10.30.50.10.10.10.20.4-0.40.30.10.3-0.3-0.30.40.20.3-0.3-0.3-0.4-0.2-0.00.3
Mg content in liver0.30.31.3-0.6-0.90.8-0.50.80.0-0.80.80.50.4-0.4-0.41.2-0.1-0.10.00.3-0.00.20.10.8
Mn content in liver0.70.83.4-1.0-1.60.8-0.50.6-0.2-0.51.11.0-0.10.20.21.8-0.6-0.80.71.10.81.00.71.2
Na content in liver0.60.73.01.71.5-0.90.8-0.70.60.5-0.6-0.70.0-0.0-0.0-1.00.50.7-0.7-1.0-0.8-0.7-0.3-0.7
Rb content in liver0.81.01.80.10.70.7-0.50.90.5-1.1-0.6-0.81.3-1.3-1.3-0.31.11.3-1.3-1.2-1.3-1.3-1.2-0.2
Se content in liver2.22.78.4-2.8-2.92.8-2.62.60.7-2.30.00.11.4-1.4-1.42.30.5-0.0-0.00.50.00.1-0.71.0
Sr content in liver0.30.31.4-0.8-1.20.7-0.60.50.0-0.40.40.4-0.00.00.01.1-0.3-0.50.40.70.50.50.30.5
Zn content in liver0.10.10.3-0.4-0.10.4-0.30.4-0.1-0.50.30.10.4-0.4-0.40.30.20.2-0.2-0.2-0.3-0.2-0.30.4
Bone: minimum diameter0.91.67.72.82.7-1.91.9-1.50.11.3-0.3-0.6-0.50.40.4-1.70.20.7-0.7-1.0-0.7-0.80.1-1.0
Time in familiar zone, hab. session 12.72.55.2-1.1-0.6-1.11.1-1.4-2.31.61.61.7-1.71.81.80.6-1.9-1.91.91.81.91.61.61.5
Time in novel zone, hab. session 13.23.15.80.60.01.7-1.61.82.4-2.1-1.5-1.72.1-2.1-2.1-0.22.01.9-2.0-1.8-2.1-1.7-1.8-1.4
Total zone transitions, hab. session 10.40.61.40.70.60.3-0.40.51.0-0.4-1.2-1.20.7-0.7-0.7-0.70.90.9-0.9-0.8-0.7-0.9-0.8-0.9
Total locomotion distance, hab. session 10.40.54.52.11.2-0.81.0-0.70.60.6-0.2-0.4-0.20.20.2-0.60.10.4-0.4-0.3-0.3-0.10.4-0.8
Locomotion velocity, hab. session 10.20.32.61.60.7-0.80.9-0.70.30.70.1-0.1-0.50.40.5-0.0-0.2-0.00.00.20.20.30.7-0.3
Time in familiar zone, hab. session 22.02.14.00.60.6-1.51.9-1.6-1.91.52.01.7-1.41.41.40.8-1.6-1.21.11.21.21.21.71.7
Time in novel zone, hab. session 20.70.71.8-0.7-0.81.1-1.41.11.2-1.0-1.1-0.80.7-0.8-0.7-0.20.80.5-0.5-0.5-0.5-0.5-0.9-0.9
Total zone transitions, hab. session 21.72.34.9-0.6-1.22.2-2.22.01.8-2.1-1.4-1.31.8-1.8-1.80.51.51.1-1.2-0.8-1.1-1.1-1.4-0.9
Total locomotion distance, hab. session 21.01.32.51.10.40.8-0.80.81.6-1.1-1.2-1.31.2-1.3-1.3-0.41.31.3-1.4-1.2-1.3-1.1-1.0-1.4
Locomotion velocity, hab. session 20.70.91.80.80.10.8-0.80.81.3-1.0-0.9-1.11.1-1.1-1.1-0.21.11.1-1.1-0.9-1.0-0.9-0.8-1.1
Novel to familiar place preference ratio0.20.20.70.40.6-0.20.10.20.4-0.1-0.3-0.30.3-0.3-0.2-0.90.40.5-0.5-0.7-0.6-0.5-0.4-0.5
Novelty place preference0.30.30.80.40.6-0.1-0.10.30.6-0.2-0.5-0.50.4-0.4-0.3-0.90.60.6-0.6-0.8-0.7-0.7-0.6-0.6
Time in novel zone, NPP test0.40.40.80.30.50.2-0.30.50.7-0.4-0.7-0.70.6-0.5-0.5-0.90.70.7-0.7-0.9-0.8-0.8-0.7-0.8
Total zone transitions, NPP test0.00.00.20.0-0.20.2-0.30.20.30.0-0.4-0.30.1-0.0-0.0-0.10.1-0.00.00.10.1-0.0-0.0-0.3
Total locomotion distance, NPP test1.01.43.31.81.1-1.81.8-1.8-0.61.70.60.5-1.41.41.4-0.7-0.9-0.70.70.50.70.81.3-0.3
Locomotion velocity, NPP test1.11.63.71.81.1-1.91.9-1.8-0.71.80.80.7-1.51.51.5-0.4-1.1-0.80.80.70.80.91.5-0.0
Intraocular pressure0.40.50.80.30.60.3-0.30.50.5-0.4-0.9-0.90.7-0.9-0.9-0.60.80.9-0.9-0.7-0.7-0.8-0.8-0.7
Delta distance traveled before/after self-admin1.31.44.42.02.1-2.12.0-1.8-0.61.40.50.4-0.90.90.7-1.7-0.40.0-0.0-0.6-0.30.10.4-0.6
Delta ambulatory time before/after self-admin1.41.65.42.32.3-2.22.1-1.9-0.51.40.40.4-0.90.90.7-1.9-0.30.1-0.1-0.8-0.5-0.10.2-0.7
Parametrial fat weight4.18.013.8-2.7-2.6-0.71.0-1.2-3.11.43.73.7-2.72.62.62.4-3.2-3.53.43.43.23.52.92.8
Pavlov. Cond. lever latency0.40.51.7-0.70.2-0.70.6-0.9-1.30.90.50.6-0.70.70.7-0.2-0.7-0.70.70.50.80.40.40.7
Pavlov. Cond. magazine entry latency0.20.31.30.4-1.00.7-0.70.41.1-0.6-0.3-0.20.2-0.2-0.20.60.30.0-0.10.1-0.20.20.1-0.7
Pavlov. Cond. change in total contacts2.02.15.11.40.31.0-1.11.32.3-1.4-1.5-1.61.5-1.5-1.5-0.61.71.6-1.6-1.5-1.7-1.4-1.3-1.8
Pavlov. Cond. index score0.40.51.90.6-0.80.9-0.90.91.4-1.0-0.4-0.40.6-0.6-0.60.50.60.4-0.4-0.2-0.5-0.1-0.2-0.7
Pavlov. Cond. latency score0.40.52.20.8-0.40.8-0.70.81.5-0.9-0.5-0.60.7-0.7-0.70.20.80.6-0.7-0.5-0.7-0.3-0.4-0.9
Pavlov. Cond. lever contacts0.30.31.41.20.20.2-0.10.61.0-0.5-0.2-0.40.5-0.5-0.50.00.50.6-0.7-0.5-0.7-0.3-0.1-0.6
Pavlov. Cond. magazine entry number0.30.42.0-0.50.9-0.90.9-0.7-1.40.90.60.5-0.50.50.5-0.3-0.6-0.30.30.20.40.00.21.0
Pavlov. Cond. intertrial magazine entries0.20.31.1-0.9-0.70.9-0.91.00.1-0.6-0.4-0.30.5-0.5-0.50.10.30.2-0.10.10.0-0.2-0.5-0.1
Pavlov. Cond. lever-magazine prob. diff.0.50.72.50.6-0.81.1-1.11.01.6-1.2-0.6-0.60.8-0.8-0.80.50.80.5-0.6-0.4-0.7-0.3-0.4-0.9
Pavlov. Cond. response bias0.10.20.80.4-0.90.4-0.30.30.7-0.30.20.2-0.10.10.10.7-0.1-0.30.20.40.20.50.5-0.2
Pavlov. Cond. lever latency1.41.95.6-2.3-2.42.4-2.32.00.7-1.9-0.4-0.21.3-1.2-1.21.90.50.1-0.10.30.0-0.2-0.80.8
Pavlov. Cond. magazine entry latency0.80.93.71.91.6-1.51.7-1.3-0.31.20.50.2-0.80.70.7-1.0-0.4-0.0-0.1-0.1-0.00.10.7-0.3
Pavlov. Cond. change in total contacts2.23.112.03.23.5-2.92.8-2.4-0.52.2-0.1-0.3-1.21.11.1-2.6-0.20.5-0.5-1.1-0.6-0.40.4-1.2
Pavlov. Cond. index score1.41.85.92.42.4-2.32.2-2.0-0.51.80.30.1-1.21.21.2-1.8-0.40.0-0.0-0.4-0.10.10.8-0.7
Pavlov. Cond. latency score1.31.65.92.42.3-2.22.1-1.8-0.41.70.2-0.0-1.11.01.0-1.7-0.30.1-0.1-0.5-0.20.00.7-0.8
Pavlov. Cond. lever contacts1.21.75.62.32.4-2.22.1-1.9-0.51.70.1-0.1-1.11.01.0-1.9-0.30.1-0.1-0.6-0.2-0.10.5-0.8
Pavlov. Cond. magazine entry number1.21.54.4-1.8-1.82.1-1.92.00.7-1.8-0.3-0.21.3-1.3-1.31.50.60.3-0.30.1-0.2-0.3-0.80.5
Pavlov. Cond. intertrial magazine entries0.30.41.5-1.2-0.91.0-1.01.00.1-0.8-0.00.00.5-0.6-0.60.90.20.1-0.0-0.0-0.1-0.1-0.50.5
Pavlov. Cond. lever-magazine prob. diff.1.51.95.52.32.2-2.42.3-2.0-0.71.90.50.3-1.41.31.3-1.6-0.6-0.20.2-0.20.10.30.9-0.5
Pavlov. Cond. response bias1.41.96.92.52.6-2.32.1-1.9-0.41.8-0.2-0.3-1.01.01.0-2.2-0.10.3-0.3-0.8-0.4-0.30.4-1.1
Time in closed arm before self-admin2.42.74.8-0.7-0.72.0-2.12.22.1-2.0-1.8-1.71.9-1.9-2.00.11.81.5-1.5-1.3-1.5-1.4-1.7-1.0
Time in closed arm after self-admin0.20.20.6-0.00.80.10.00.30.3-0.1-0.5-0.80.5-0.5-0.6-0.60.50.7-0.7-0.4-0.4-0.7-0.3-0.4
Time in open arm before self-admin3.23.46.91.31.1-2.52.6-2.6-1.92.41.91.7-2.12.22.3-0.4-1.9-1.61.51.31.51.32.10.8
Time in open arm after self-admin0.91.02.21.10.1-1.31.2-1.3-0.51.01.21.3-1.31.41.5-0.1-0.9-1.01.00.50.51.00.90.1
Bone: periosteal estimation0.81.64.31.41.5-2.12.1-2.0-1.11.90.90.8-1.41.41.4-0.5-1.0-0.70.70.40.60.51.20.3
Bone: periosteal perimeter0.71.12.61.00.9-1.51.6-1.4-0.91.50.90.7-1.11.21.20.2-1.0-0.70.70.70.80.61.20.7
Bone: post-yield work1.11.55.32.02.3-1.00.9-0.60.50.4-0.9-1.10.4-0.4-0.4-2.10.91.2-1.2-1.5-1.3-1.2-0.7-1.6
Progressive ratio test 1 active lever presses2.32.44.71.91.7-0.1-0.20.41.7-0.3-2.2-2.11.1-1.1-1.1-1.81.71.8-1.7-1.9-1.7-1.8-1.4-2.0
Progressive ratio test 1 breakpoint1.51.63.81.91.8-0.40.20.01.20.1-1.7-1.70.7-0.7-0.7-1.71.21.4-1.4-1.5-1.3-1.4-0.9-1.6
Progressive ratio test 1 inactive lever presses2.93.25.02.12.00.2-0.20.81.8-0.8-1.9-2.11.6-1.6-1.6-1.91.92.2-2.2-2.2-2.2-2.0-1.7-2.1
Progressive ratio test 2 active lever presses1.82.04.91.11.10.4-0.70.51.8-0.6-2.2-2.11.2-1.2-1.2-1.31.61.6-1.6-1.6-1.5-1.5-1.3-1.8
Progressive ratio test 2 breakpoint1.51.74.41.00.90.4-0.70.61.7-0.5-2.1-1.91.1-1.1-1.1-1.11.51.4-1.4-1.4-1.3-1.4-1.1-1.6
Progressive ratio test 2 inactive lever presses5.76.611.22.53.00.4-0.31.22.5-1.1-3.0-3.32.5-2.5-2.5-2.52.83.3-3.3-3.0-2.9-3.1-2.3-2.7
Incentive Sensitization - Responses0.50.51.90.20.30.4-0.60.30.8-0.3-1.4-1.20.6-0.7-0.7-0.50.80.7-0.7-0.7-0.6-0.7-0.7-0.9
Incentive Sensitization - Breakpoint0.40.41.60.00.30.3-0.50.20.7-0.2-1.2-1.00.6-0.6-0.6-0.50.70.6-0.6-0.6-0.5-0.7-0.7-0.8
Sum of active levers in priming session hrs 5-60.10.10.30.10.4-0.40.4-0.5-0.40.50.0-0.0-0.10.20.3-0.2-0.3-0.10.20.20.30.00.30.2
Progressive ratio0.10.10.50.70.10.10.00.40.6-0.2-0.1-0.30.2-0.1-0.10.10.20.3-0.3-0.1-0.3-0.10.1-0.3
Food seeking constrained by brief footshock0.91.14.72.21.7-1.81.9-1.4-0.31.50.40.2-1.01.11.0-0.8-0.6-0.20.10.10.20.31.0-0.2
Seeking ratio, punishment vs. effort0.20.21.10.81.0-0.70.6-0.50.00.4-0.3-0.3-0.10.00.1-0.80.20.4-0.3-0.5-0.4-0.4-0.1-0.4
Retroperitoneal fat weight0.72.49.6-3.0-3.11.3-1.30.7-0.7-0.61.21.5-0.60.60.61.9-1.1-1.71.71.91.61.70.71.3
Reaction time number correct0.10.10.20.0-0.4-0.1-0.0-0.3-0.50.00.20.5-0.40.30.3-0.0-0.3-0.40.40.30.30.4-0.10.2
Reaction time mean minus median0.20.30.90.10.4-0.90.8-0.9-0.50.70.70.7-0.60.70.7-0.3-0.5-0.50.40.10.20.20.50.3
Reaction time mean minus median AUC0.70.92.20.10.4-1.31.2-1.5-1.01.11.21.2-1.11.21.2-0.4-0.9-0.90.90.30.40.50.70.5
Reaction time num false alarms0.40.61.4-0.9-0.71.1-1.20.90.6-1.1-0.6-0.40.8-0.9-0.90.50.70.4-0.4-0.5-0.6-0.4-0.9-0.0
Reaction time num false alarms AUC0.40.61.6-0.9-0.91.2-1.21.10.6-1.2-0.5-0.40.8-0.9-0.90.70.70.4-0.4-0.4-0.5-0.4-0.80.1
Reaction time trials correct on left0.10.10.20.0-0.4-0.1-0.0-0.3-0.50.00.20.5-0.40.30.3-0.0-0.3-0.40.40.30.30.4-0.10.2
Reaction time trials on left0.10.10.3-0.0-0.4-0.1-0.0-0.3-0.50.10.30.6-0.40.40.40.0-0.4-0.40.50.30.40.5-0.00.3
Reaction time mean0.10.10.50.00.2-0.60.3-0.7-0.00.4-0.00.2-0.30.40.4-0.3-0.1-0.20.2-0.3-0.1-0.2-0.00.0
Reaction time mean AUC0.10.10.4-0.10.0-0.50.2-0.6-0.00.30.20.4-0.20.40.4-0.0-0.1-0.30.3-0.1-0.1-0.10.10.2
Median of all reaction times0.00.00.10.00.1-0.2-0.0-0.40.30.1-0.3-0.10.00.10.1-0.10.20.00.0-0.4-0.2-0.3-0.2-0.0
Reaction time omissions0.40.51.4-0.7-0.7-0.20.2-0.4-0.70.11.11.2-0.50.70.70.8-0.7-0.80.80.60.50.60.51.0
Reaction time false alarm rate0.40.61.1-0.8-0.41.0-1.01.00.8-1.0-0.7-0.70.9-1.0-1.00.50.80.6-0.6-0.5-0.7-0.6-0.7-0.1
Reaction time premature initiation rate1.01.32.71.71.00.3-0.30.61.7-0.8-1.1-1.31.1-1.1-1.1-0.61.31.4-1.4-1.3-1.4-1.3-1.0-1.3
Reaction time premature initiations0.71.02.51.60.70.3-0.30.41.3-0.8-0.9-1.00.8-0.9-0.9-0.71.01.2-1.2-1.1-1.2-1.0-1.0-1.2
Std. dev. reaction times0.20.31.10.40.8-1.00.7-1.1-0.20.60.10.3-0.40.60.6-0.9-0.1-0.10.1-0.5-0.3-0.3-0.0-0.2
Reaction time trials completed0.10.10.3-0.0-0.4-0.1-0.0-0.3-0.50.10.30.6-0.40.40.40.0-0.4-0.40.50.30.40.5-0.00.3
Reaction time trials AUC0.20.30.8-0.3-0.7-0.10.0-0.4-0.80.20.60.9-0.70.60.60.3-0.6-0.70.80.70.70.80.20.6
Run reversals in cocaine runway, females0.30.31.20.60.9-0.70.4-0.70.00.3-0.5-0.30.00.10.1-1.10.30.4-0.3-0.8-0.6-0.5-0.6-0.5
Run reversals in cocaine runway, males4.74.68.9-1.9-2.1-0.50.7-0.8-2.30.93.02.9-2.01.91.92.2-2.3-2.52.52.52.22.62.22.4
Latency to leave start box in cocaine runway0.70.71.70.70.9-0.1-0.2-0.10.6-0.2-1.1-0.90.6-0.6-0.6-1.30.91.0-0.8-1.2-1.0-1.1-1.2-1.0
Latency to leave start box in cocaine runway, F0.70.81.80.40.70.3-0.50.30.7-0.7-0.8-0.70.9-0.9-0.9-1.11.01.1-1.0-1.3-1.2-1.1-1.3-0.9
Latency to leave start box in cocaine runway, M0.00.00.10.20.1-0.30.0-0.4-0.10.3-0.4-0.1-0.30.30.3-0.1-0.1-0.10.2-0.00.20.0-0.1-0.1
Std. dev. time between licks in bursts2.63.16.22.51.70.4-0.21.12.1-1.2-1.3-1.81.7-1.7-1.7-1.41.92.2-2.3-2.1-2.3-1.9-1.4-2.1
Total sessions with >9 infusions0.40.51.5-0.6-1.01.1-1.21.00.9-1.0-0.6-0.40.6-0.6-0.60.50.60.3-0.3-0.3-0.4-0.1-0.6-0.3
Short access day 1 total inactive lever presses4.44.97.72.12.20.6-0.61.32.3-1.3-2.5-2.72.2-2.2-2.2-2.02.52.8-2.8-2.7-2.6-2.6-2.3-2.3
Short access day 10 total inactive lever presses0.60.73.61.41.9-0.81.0-0.40.10.4-0.3-0.70.3-0.2-0.2-1.30.30.8-0.9-0.7-0.6-0.9-0.2-0.7
Short access day 1 total infusions0.30.30.8-0.00.00.5-0.70.60.8-0.5-0.9-0.80.5-0.5-0.5-0.30.70.6-0.6-0.7-0.7-0.5-0.6-0.7
Short access day 10 total infusions0.50.51.2-0.3-0.20.7-0.90.80.8-0.7-1.1-0.90.8-0.7-0.7-0.10.80.6-0.6-0.7-0.7-0.7-0.7-0.6
Short access total infusions0.40.41.4-0.7-0.81.0-1.20.90.7-0.7-0.9-0.70.6-0.5-0.50.40.60.3-0.3-0.3-0.3-0.3-0.5-0.3
Short access day 1 locomotion0.20.30.7-0.3-0.40.6-0.70.60.6-0.8-0.3-0.10.5-0.5-0.50.00.50.4-0.4-0.6-0.7-0.2-0.7-0.3
Short access day 10 total locomotion1.61.85.42.31.7-0.20.20.31.6-0.4-1.3-1.51.0-1.0-1.0-1.41.31.6-1.6-1.6-1.6-1.4-0.9-1.6
Short access total locomotion0.90.91.90.0-0.41.2-1.21.31.4-1.2-0.9-0.91.2-1.1-1.10.21.10.9-0.9-0.8-1.0-0.7-0.9-0.6
One hour access (0.3 mA shock)2.73.17.32.72.1-0.40.00.12.1-0.2-2.3-2.31.1-1.0-1.0-2.01.82.0-1.9-2.2-2.0-1.8-1.3-2.4
Compulsive drug intake0.00.00.10.3-0.0-0.20.2-0.1-0.10.10.20.2-0.20.20.20.0-0.1-0.10.10.10.10.10.20.0
One hour access (shock baseline)1.92.24.31.41.20.4-0.60.71.9-0.7-2.1-2.01.3-1.3-1.3-1.31.71.7-1.7-1.8-1.7-1.6-1.4-1.8
Social response proportion0.60.63.21.21.8-1.21.5-1.0-0.80.80.50.1-0.20.30.3-1.2-0.30.3-0.4-0.2-0.1-0.30.4-0.3
Social responses0.20.31.41.21.0-0.61.0-0.1-0.40.20.80.3-0.00.00.0-0.2-0.20.3-0.3-0.0-0.2-0.10.30.2
Social time0.91.25.52.12.3-1.51.4-1.2-0.11.0-0.5-0.6-0.20.30.3-1.90.30.7-0.7-1.1-0.8-1.0-0.2-0.9
Soleus weight0.10.30.8-0.8-0.80.3-0.20.2-0.5-0.10.60.6-0.10.20.20.9-0.5-0.50.50.60.50.50.30.8
Bone: stiffness0.40.62.30.91.5-1.31.3-1.1-0.81.10.30.1-0.70.40.5-1.3-0.30.0-0.0-0.3-0.00.00.3-0.3
Tibialis anterior weight0.93.25.3-2.2-1.6-0.50.5-0.9-2.31.21.82.1-1.61.81.81.6-2.0-2.22.32.12.31.81.52.2
Time to tail flick, vehicle, before self-admin0.60.61.3-0.5-0.51.1-1.11.10.8-1.0-0.9-0.80.9-0.8-1.00.20.70.6-0.6-0.4-0.5-0.6-0.7-0.4
Time to tail flick, vehicle, after self-admin0.10.10.40.5-0.00.10.20.50.3-0.10.30.0-0.0-0.0-0.00.6-0.1-0.0-0.10.40.20.20.50.2
Time to tail flick, test, before self-admin3.63.56.20.60.80.9-1.41.02.1-1.4-2.4-2.21.7-1.7-1.7-1.82.32.1-2.0-2.5-2.3-2.0-2.4-2.2
Time to tail flick, test, after self-admin0.10.10.30.40.10.1-0.20.30.5-0.3-0.4-0.30.3-0.2-0.4-0.40.40.4-0.4-0.5-0.5-0.2-0.6-0.5
Delta time to tail flick, vehicle, before/after SA0.20.21.41.20.5-0.70.8-0.4-0.00.40.50.4-0.50.40.5-0.0-0.3-0.10.10.10.00.40.50.0
Delta time to tail flick, test, before/after SA2.32.14.0-0.7-1.4-0.10.5-0.2-1.30.51.91.8-1.21.21.11.9-1.7-1.71.62.01.81.81.61.7
Tibia length1.13.08.61.42.2-2.92.6-2.9-1.62.60.70.7-1.82.01.9-2.5-1.2-0.80.80.10.70.51.1-0.7
Ambulatory time before self-admin0.00.00.20.40.00.1-0.00.00.30.2-0.4-0.5-0.1-0.00.20.10.00.1-0.10.30.30.10.3-0.1
Ambulatory time after self-admin2.32.510.63.33.0-2.52.4-2.2-0.21.9-0.1-0.4-1.10.90.8-2.4-0.20.4-0.4-0.8-0.4-0.10.4-1.2
Bone: tissue strength1.41.46.61.62.3-1.41.3-1.00.20.7-0.3-0.6-0.10.10.1-2.60.50.9-0.9-1.3-1.1-0.8-0.5-1.8
Total heroin consumption0.50.61.71.11.3-0.20.3-0.20.70.2-1.0-1.20.6-0.7-0.6-0.90.70.9-0.9-0.7-0.6-0.8-0.4-0.8
Bone: trabecular number0.50.82.30.91.2-1.51.4-1.4-0.91.30.40.4-1.11.01.0-1.1-0.6-0.40.4-0.00.30.50.6-0.6
Bone: trabecular spacing0.40.61.40.4-0.2-0.50.7-0.6-0.40.51.10.9-0.60.80.80.9-0.8-0.70.70.80.70.71.01.2
Bone: trabecular thickness0.10.10.6-0.8-0.3-0.0-0.3-0.2-0.30.2-0.20.1-0.20.20.2-0.1-0.1-0.30.30.00.20.1-0.20.0
Bone: trabecular tissue density2.53.69.3-3.0-3.10.9-0.80.4-1.30.11.41.8-1.01.11.12.9-1.7-2.22.22.52.32.01.42.6
Water consumed over 24 hours0.20.20.80.50.5-0.80.6-0.9-0.50.70.10.1-0.50.50.5-0.7-0.3-0.20.20.00.20.20.3-0.4
Number of responses in last shaping day2.52.65.01.51.10.7-0.91.12.0-1.0-2.2-2.21.6-1.6-1.6-1.31.81.9-1.8-1.8-1.7-1.8-1.5-1.8