Hub : Genes

Apc2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc isoform ratio XM_039078649.1 0.03 0.03 1.5e-03 0.03 0.02 0.02 0.02 4.8e-04 1.3e-03 2.1e-03 1.1e-03
2 Adipose intron excision ratio chr7_9408689_9409223 0.13 0.08 4.2e-15 0.12 0.12 0.12 0.12 5.5e-13 1.7e-13 1.3e-13 1.9e-13
3 Adipose isoform ratio XM_017594717.2 0.06 0.04 1.1e-06 0.04 0.04 0.04 0.04 8.7e-05 8.2e-06 1.5e-05 2.3e-05
4 Adipose mRNA stability Apc2 0.03 0.03 2.6e-04 0.01 0.02 0.02 0.01 1.4e-02 4.7e-03 3.2e-03 1.1e-02
5 Adipose alternative TSS XM_039078652.1 0.05 0.04 7.4e-06 0.03 0.04 0.04 0.03 4.1e-04 4.2e-05 5.2e-05 1.1e-04
6 Adipose alternative TSS XM_039078652.1 0.05 0.04 5.7e-06 0.03 0.04 0.04 0.04 1.5e-04 3.6e-05 4.7e-05 8.8e-05
7 Liver gene expression Apc2 0.16 0.1 3.3e-14 0.12 0.1 0.1 0.11 9.7e-13 7.6e-11 3.6e-11 5.3e-12
8 Adipose alternative TSS XM_039078649.1 0.03 0.02 1.9e-03 0.01 0.01 0.01 0.01 1.6e-02 1.1e-02 8.1e-03 1.8e-02
9 Adipose gene expression Apc2 0.32 0.16 0.0e+00 0.25 0.26 0.27 0.27 8.1e-28 2.3e-29 1.7e-29 1.4e-29
10 PL alternative TSS XM_039078649.1 0.03 0.03 1.2e-04 0.03 0.03 0.04 0.03 1.5e-04 1.3e-04 7.0e-05 1.6e-04
11 pVTA gene expression Apc2 0.24 0.14 7.5e-10 0.2 0.22 0.19 0.22 3.7e-09 4.6e-10 1.2e-08 5.7e-10
12 Brain alternative TSS XM_039078649.1 0.03 0.02 2.4e-03 0.02 0.02 0.02 0.02 7.9e-03 7.4e-03 4.4e-03 7.6e-03
13 BLA gene expression Apc2 0.09 0.06 1.2e-05 0.06 0.07 0.05 0.06 3.9e-04 1.1e-04 9.6e-04 4.1e-04
14 IL gene expression Apc2 0.24 0.15 1.4e-04 0.13 0.11 0.12 0.12 4.9e-04 1.3e-03 1.0e-03 6.4e-04
15 OFC gene expression Apc2 0.17 0.11 1.7e-04 0.16 0.16 0.15 0.16 1.0e-04 1.1e-04 2.1e-04 1.5e-04
16 Brain gene expression Apc2 0.22 0.1 0.0e+00 0.23 0.21 0.21 0.22 1.1e-21 2.2e-19 3.7e-19 2.2e-20
17 PL gene expression Apc2 0.09 0.06 3.7e-12 0.12 0.1 0.11 0.12 4.1e-13 1.3e-11 6.3e-12 1.5e-12
18 NAcc gene expression Apc2 0.08 0.06 1.4e-10 0.1 0.09 0.1 0.09 2.2e-11 1.4e-10 4.5e-11 5.0e-11

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density0.20.31.1-1.00.5-0.20.40.00.11.1-0.5-0.5-0.50.30.30.5-0.6-0.6-0.7-0.7-0.7
Area under the delay curve2.42.63.01.2-1.61.7-1.71.71.7-1.31.51.51.41.71.71.6-1.7-1.7-1.6-1.6-1.7
BMI with tail7.022.624.14.8-4.94.9-4.94.84.8-4.84.94.94.94.84.94.7-4.5-4.5-4.5-4.6-4.5
BMI without tail2.75.69.03.0-2.72.6-2.72.42.4-2.72.52.52.52.32.22.1-1.9-1.9-1.8-1.7-1.9
Body weight1.35.35.92.4-2.42.4-2.42.42.4-2.32.32.32.42.32.32.3-2.2-2.2-2.1-2.1-2.1
Weight adjusted by age0.50.51.51.2-1.00.9-0.90.80.8-1.00.80.70.80.60.70.5-0.2-0.2-0.3-0.5-0.3
Bone surface0.61.04.4-2.01.2-0.91.1-0.6-0.62.1-1.3-1.3-1.3-0.3-0.3-0.0-0.3-0.3-0.4-0.3-0.4
Bone volume0.61.04.5-1.91.2-0.81.0-0.5-0.52.1-1.4-1.3-1.3-0.2-0.10.1-0.3-0.3-0.4-0.4-0.4
Breakpoint value in progressive ratio session5.56.17.1-1.92.3-2.52.4-2.5-2.52.1-2.3-2.4-2.4-2.6-2.6-2.62.72.72.62.62.6
Number of licking bursts0.10.10.40.6-0.40.4-0.30.30.3-0.60.40.40.40.10.30.00.20.20.1-0.00.1
Context. condit. distance diff. score0.30.30.60.8-0.80.6-0.70.50.5-0.60.60.60.60.50.30.5-0.6-0.6-0.5-0.0-0.6
Locomotion velocity, session 10.60.71.6-1.31.1-0.90.9-0.8-0.81.2-1.0-0.9-1.0-0.7-0.6-0.60.40.40.60.40.5
Locomotion distance, session 10.30.42.0-1.40.9-0.80.8-0.6-0.50.9-0.6-0.5-0.5-0.4-0.3-0.1-0.2-0.2-0.20.3-0.2
Locomotion velocity, session 24.25.09.1-3.02.7-2.52.5-2.3-2.32.5-2.3-2.2-2.3-2.1-2.2-1.91.51.51.82.01.6
Locomotion distance, session 21.82.66.8-2.62.2-1.92.0-1.6-1.62.0-1.8-1.7-1.7-1.4-1.1-1.10.90.91.00.81.0
Locomotion velocity, session 36.47.58.4-2.52.7-2.82.7-2.8-2.82.5-2.6-2.7-2.7-2.8-2.9-2.82.72.72.82.92.8
Locomotion distance, session 30.00.00.10.3-0.20.1-0.20.00.0-0.10.10.10.10.0-0.1-0.00.00.0-0.00.1-0.0
Stereotopy head waving bouts, day 35.36.37.5-2.72.7-2.72.6-2.7-2.62.5-2.5-2.5-2.5-2.6-2.5-2.52.22.22.32.42.3
Stereotopy head waving duration, day 36.37.58.4-2.82.9-2.92.8-2.9-2.92.6-2.7-2.7-2.8-2.8-2.8-2.72.52.52.62.72.6
Locomotion velocity, session 70.60.71.2-0.40.6-0.70.6-0.7-0.71.1-1.0-1.0-1.0-0.7-0.9-0.80.80.80.91.00.9
Locomotion distance, session 70.20.21.01.0-0.70.6-0.70.50.5-0.60.50.40.50.40.30.3-0.1-0.1-0.0-0.1-0.1
Stereotopy head waving bouts, day 70.10.10.3-0.60.3-0.30.2-0.2-0.20.5-0.3-0.3-0.3-0.1-0.00.0-0.3-0.3-0.30.0-0.3
Stereotopy head waving duration, day 70.30.41.1-1.00.7-0.70.7-0.6-0.61.0-0.7-0.7-0.7-0.4-0.3-0.30.10.10.10.20.1
Locomotion velocity, session 80.70.92.5-1.61.2-1.11.1-0.9-0.91.4-1.1-1.0-1.1-0.7-0.7-0.50.30.30.40.50.4
Locomotion distance, session 80.20.20.6-0.80.6-0.70.5-0.6-0.60.5-0.4-0.4-0.4-0.5-0.6-0.30.20.20.30.60.2
Degree of sensitization distance0.40.40.50.6-0.60.7-0.60.70.7-0.50.60.60.60.70.60.7-0.6-0.6-0.6-0.5-0.6
Degree of sensitization stereotypy1.82.03.01.0-1.31.3-1.31.41.4-0.91.21.21.21.51.61.5-1.6-1.6-1.7-1.5-1.7
Conditioned locomotion1.72.03.31.8-1.61.6-1.51.41.4-1.81.61.61.61.31.41.2-1.0-1.0-0.9-1.1-0.9
Cocaine response after cond. corrected5.86.510.83.3-2.92.8-2.92.72.7-2.92.82.72.72.52.12.3-2.1-2.1-1.9-2.0-2.0
Cocaine response after cond. not corrected6.26.811.43.4-3.02.9-3.02.72.7-3.02.82.82.82.52.12.3-2.1-2.1-2.0-2.0-2.1
Cocaine response before conditioning0.50.60.9-0.80.8-0.80.8-0.8-0.80.9-0.9-0.9-0.9-0.8-0.6-0.80.70.70.70.80.7
Saline control response0.10.10.20.3-0.20.3-0.20.30.3-0.40.30.30.30.20.30.2-0.1-0.1-0.1-0.3-0.2
Bone: connectivity density0.20.41.1-0.4-0.10.3-0.20.40.50.40.10.10.10.60.60.8-1.0-1.0-1.0-1.0-1.1
Bone: cortical apparent density0.81.11.70.9-0.91.1-1.01.11.1-1.01.01.01.01.11.11.0-1.0-1.0-1.0-1.3-1.0
Bone: cortical area0.50.81.30.5-0.70.8-0.80.90.9-0.10.50.50.51.01.01.1-1.1-1.1-1.1-1.1-1.1
Bone: cortical porosity0.60.61.2-1.10.9-0.80.9-0.8-0.81.1-1.0-1.0-0.9-0.7-0.6-0.60.60.60.50.50.6
Bone: cortical porosity0.10.10.6-0.80.4-0.30.4-0.2-0.20.7-0.5-0.4-0.4-0.1-0.10.1-0.1-0.1-0.2-0.2-0.1
Bone: cortical thickness1.11.82.51.0-1.21.3-1.21.41.4-0.91.11.11.21.51.51.5-1.5-1.5-1.5-1.6-1.4
Bone: cortical thickness0.10.10.40.6-0.30.3-0.30.20.1-0.40.20.10.10.10.2-0.10.30.30.30.20.3
Bone: cortical tissue density0.50.71.20.7-0.80.9-0.80.90.9-0.80.80.80.80.90.90.8-0.8-0.8-0.8-1.1-0.8
Condit. Reinf. active minus inactive responses4.65.16.5-2.22.2-2.42.2-2.4-2.42.1-2.2-2.2-2.2-2.4-2.5-2.32.12.12.22.52.2
Condit. Reinf. active-inactive response ratio2.22.33.3-1.11.4-1.51.4-1.6-1.61.2-1.4-1.4-1.4-1.6-1.8-1.71.61.61.61.81.7
Condit. Reinf. active responses4.15.07.1-2.72.5-2.52.4-2.4-2.42.3-2.2-2.2-2.3-2.3-2.3-2.11.91.91.92.21.9
Condit. Reinf. inactive responses1.01.23.3-1.81.4-1.31.3-1.1-1.11.4-1.2-1.1-1.2-1.0-0.9-0.80.60.60.70.70.7
Incentive salience index mean2.53.04.2-2.11.9-1.91.8-1.9-1.91.8-1.7-1.7-1.8-1.8-1.9-1.71.41.41.41.81.5
Condit. Reinf. lever presses0.20.21.2-1.10.6-0.50.5-0.3-0.20.8-0.4-0.4-0.4-0.10.00.2-0.4-0.4-0.4-0.2-0.3
Condit. Reinf. active minus inactive responses2.02.53.7-1.11.4-1.41.5-1.5-1.51.3-1.5-1.5-1.5-1.6-1.3-1.81.91.91.81.51.9
Condit. Reinf. active-inactive response ratio0.10.10.40.20.10.00.1-0.1-0.1-0.40.10.00.0-0.20.2-0.40.60.60.60.00.6
Condit. Reinf. active responses1.92.73.4-1.31.5-1.51.6-1.6-1.61.7-1.8-1.8-1.8-1.6-1.2-1.71.81.81.81.51.8
Condit. Reinf. inactive responses1.11.32.2-0.91.0-1.11.0-1.1-1.11.5-1.4-1.4-1.4-1.1-1.0-1.21.11.11.11.21.1
Condit. Reinf. lever presses2.23.04.1-1.21.5-1.61.6-1.7-1.71.4-1.6-1.7-1.7-1.8-1.6-1.92.02.02.01.82.0
Condit. Reinf. lever reinforcers received1.41.92.8-0.91.2-1.21.3-1.3-1.31.3-1.5-1.5-1.5-1.4-1.0-1.51.71.71.61.31.6
Conditioned reinforcement - actives2.32.33.0-1.31.4-1.51.6-1.5-1.51.5-1.6-1.6-1.5-1.5-1.5-1.51.71.71.41.41.4
Conditioned reinforcement - inactives0.50.61.21.1-0.90.8-0.90.70.7-1.00.90.90.90.70.60.6-0.5-0.5-0.6-0.5-0.6
Conditioned locomotion7.38.89.8-2.72.9-3.03.0-3.0-3.02.8-2.9-3.0-2.9-3.0-3.1-3.03.13.12.92.92.9
Patch foraging indifference point 0 sec0.10.20.50.3-0.40.4-0.40.50.5-0.20.30.30.30.50.60.5-0.5-0.5-0.5-0.7-0.5
Patch foraging indifference point AUC0.80.91.3-0.80.9-0.91.0-1.0-1.00.7-0.9-0.9-0.8-1.0-0.9-1.01.11.11.01.01.0
Delay disc. indifference point, 0s delay6.77.310.21.5-2.32.5-2.42.72.7-2.02.42.52.52.93.03.0-3.2-3.2-3.2-3.2-3.1
Delay disc. indifference point, 16s delay0.10.10.20.3-0.30.3-0.40.30.3-0.30.40.40.20.40.40.3-0.5-0.5-0.4-0.4-0.5
Delay disc. indifference point, 2s delay5.86.47.72.0-2.52.5-2.52.62.6-2.02.42.42.42.72.62.7-2.7-2.7-2.8-2.6-2.7
Delay disc. indifference point, 24s delay0.90.91.61.2-1.01.0-1.01.01.0-0.90.90.90.81.01.00.9-0.8-0.8-0.7-0.9-0.8
Delay disc. indifference point, 4s delay1.01.11.70.6-0.91.0-1.01.01.0-0.60.90.90.81.11.01.1-1.3-1.3-1.2-1.0-1.3
Delay disc. indifference point, 8s delay1.41.41.91.0-1.41.4-1.31.31.3-1.21.21.21.21.31.31.2-1.1-1.1-1.0-1.0-1.0
Indifference point function ln k0.30.40.60.8-0.70.7-0.70.70.7-0.40.50.50.50.60.60.6-0.6-0.6-0.5-0.5-0.6
Indifference point function log k0.30.40.60.8-0.70.7-0.70.70.7-0.40.50.50.50.60.60.6-0.6-0.6-0.5-0.5-0.6
Patch foraging total patch changes 0 sec0.10.10.30.3-0.30.4-0.30.40.4-0.20.30.30.30.40.50.4-0.4-0.4-0.4-0.6-0.4
Patch foraging total patch changes 12 sec0.40.51.20.9-0.80.7-0.70.70.7-1.10.90.91.00.60.60.6-0.3-0.3-0.4-0.4-0.4
Patch foraging total patch changes 18 sec1.21.51.6-1.21.3-1.21.3-1.2-1.31.1-1.2-1.2-1.2-1.3-1.2-1.21.21.21.21.21.2
Patch foraging total patch changes 24 sec0.10.10.2-0.40.4-0.30.4-0.3-0.30.3-0.3-0.3-0.2-0.3-0.2-0.30.30.30.30.10.3
Patch foraging total patch changes 6 sec0.20.30.6-0.70.7-0.60.7-0.6-0.60.7-0.7-0.7-0.6-0.6-0.3-0.50.60.60.60.20.6
Patch foraging time to switch 0 sec1.01.53.00.3-0.80.9-0.91.11.1-0.81.11.21.21.21.01.5-1.7-1.7-1.6-1.2-1.5
Patch foraging water rate 0 sec0.10.21.11.1-0.60.5-0.40.20.2-0.50.30.20.20.10.2-0.20.50.50.30.20.3
Patch foraging water rate 12 sec1.32.04.72.2-1.71.7-1.71.51.4-1.81.61.51.51.31.41.0-0.8-0.8-0.7-1.0-0.8
Patch foraging water rate 18 sec0.30.41.51.2-0.50.4-0.40.10.0-1.00.40.30.3-0.2-0.2-0.50.90.90.90.70.8
Patch foraging water rate 24 sec0.71.03.82.0-1.41.2-1.20.90.9-1.71.21.11.10.60.60.30.00.0-0.0-0.2-0.1
Patch foraging water rate 6 sec0.30.41.10.50.0-0.10.2-0.3-0.4-0.1-0.2-0.3-0.3-0.5-0.5-0.71.01.01.10.81.0
Seeking ratio, delayed vs. immediate footshock4.75.46.5-2.42.4-2.42.4-2.3-2.32.5-2.5-2.5-2.4-2.3-2.3-2.22.22.22.12.12.1
Distance traveled before self-admin0.50.50.80.4-0.60.7-0.60.70.7-0.40.60.60.60.80.90.8-0.7-0.7-0.9-0.9-0.9
Distance traveled after self-admin0.60.70.9-0.80.8-0.90.9-0.8-0.80.9-0.9-0.9-0.8-0.8-0.7-0.70.80.80.80.70.7
Extensor digitorum longus weight5.120.024.04.9-4.84.7-4.84.64.6-4.74.74.74.74.44.24.3-4.1-4.1-4.2-3.8-4.1
Bone: elastic displacement0.20.30.4-0.60.6-0.50.6-0.5-0.50.7-0.6-0.6-0.6-0.4-0.4-0.50.50.50.50.40.5
Bone: elastic work0.20.30.40.4-0.50.6-0.50.60.6-0.00.20.20.30.60.60.6-0.6-0.6-0.5-0.5-0.6
Bone: endosteal estimation0.20.40.60.4-0.60.6-0.60.60.6-0.30.50.50.40.70.60.6-0.8-0.8-0.7-0.4-0.8
Bone: endosteal perimeter0.30.61.4-0.90.8-0.80.7-0.7-0.71.2-1.0-0.9-1.0-0.6-0.7-0.60.40.40.50.70.4
Epididymis fat weight0.20.50.9-0.60.7-0.80.7-0.8-0.80.1-0.3-0.3-0.4-0.9-0.8-0.80.80.80.80.90.8
Delta time in closed arm before/after self-admin1.11.13.11.7-1.41.2-1.21.01.0-1.71.31.21.20.80.80.6-0.2-0.2-0.4-0.4-0.4
Delta time in open arm before/after self-admin1.21.11.70.7-0.91.0-1.01.11.1-0.91.01.01.01.11.11.1-1.3-1.3-1.1-1.1-1.1
Diff in mean of infusions in LGA sessions2.02.22.6-1.41.5-1.61.5-1.6-1.61.4-1.4-1.4-1.5-1.6-1.6-1.51.31.31.51.61.4
Delay discount exponential model param2.22.42.7-1.21.6-1.61.6-1.6-1.61.3-1.4-1.5-1.4-1.6-1.6-1.61.61.61.51.51.6
Extinction: sum of active levers before priming1.11.12.2-0.40.8-1.01.0-1.1-1.10.5-0.8-0.9-0.8-1.2-1.2-1.21.51.51.21.31.2
Active lever presses in extinction session 62.82.83.3-1.51.6-1.71.7-1.7-1.71.7-1.8-1.8-1.7-1.6-1.5-1.61.81.81.61.51.6
Bone: final force1.22.02.61.1-1.31.5-1.31.51.5-0.81.11.11.11.61.61.6-1.6-1.6-1.6-1.5-1.5
Bone: final moment1.01.52.10.9-1.11.3-1.21.41.4-0.60.91.01.01.41.41.4-1.4-1.4-1.4-1.3-1.4
Food consumed during 24 hour testing period0.60.71.01.0-1.01.0-0.90.90.9-0.80.80.80.80.90.90.8-0.7-0.7-0.9-0.7-0.9
Glucose1.62.43.31.6-1.61.6-1.61.61.6-1.51.51.51.51.61.71.5-1.4-1.4-1.4-1.8-1.5
Heart weight0.20.30.8-0.20.4-0.50.5-0.6-0.60.2-0.4-0.4-0.4-0.6-0.5-0.70.80.80.90.50.9
Delay discount hyperbolic model param3.13.33.7-1.51.8-1.91.9-1.9-1.91.5-1.7-1.7-1.7-1.9-1.9-1.91.91.91.91.81.9
Intermittent access intake day 1-15 change6.96.87.9-2.22.4-2.62.6-2.6-2.62.4-2.6-2.6-2.6-2.7-2.6-2.72.82.82.72.62.7
Intermittent access intake escalation6.26.18.5-1.82.1-2.32.3-2.4-2.51.9-2.3-2.3-2.3-2.6-2.5-2.62.92.92.72.72.7
Intermittent access intake escalation 27.67.510.0-2.02.5-2.62.6-2.7-2.72.1-2.5-2.6-2.5-2.9-2.8-2.93.23.23.12.93.1
Intermitt. access day 1 inactive lever presses0.10.10.50.2-0.0-0.10.1-0.2-0.20.0-0.2-0.3-0.2-0.3-0.3-0.40.70.70.50.50.5
Intermitt. access day 15 inactive lever presses0.50.50.8-0.50.6-0.70.6-0.7-0.70.5-0.6-0.6-0.6-0.8-0.8-0.80.80.80.90.80.9
Intermitt. access escalation Index0.20.20.6-0.1-0.20.3-0.20.40.40.30.00.10.10.50.50.5-0.7-0.7-0.8-0.6-0.8
Intermittent access day 1 total infusions0.00.00.10.2-0.20.2-0.20.20.2-0.10.20.20.20.20.20.2-0.2-0.2-0.2-0.2-0.2
Intermittent access day 15 total infusions2.02.23.1-1.01.3-1.41.4-1.5-1.51.2-1.3-1.4-1.4-1.5-1.6-1.61.81.81.71.61.7
Intermittent access terminal intake (last 3 days)1.11.21.7-0.80.9-1.01.0-1.1-1.11.0-1.1-1.1-1.0-1.1-1.1-1.11.31.31.21.11.2
Intermittent access total infusions0.20.20.5-0.20.3-0.40.4-0.5-0.50.3-0.4-0.4-0.4-0.5-0.5-0.50.70.70.50.50.5
Intermittent access day 1 locomotion0.40.40.6-0.50.6-0.60.6-0.7-0.70.5-0.5-0.5-0.6-0.7-0.7-0.70.70.70.70.80.7
Intermittent access day 15 total locomotion3.74.04.5-1.82.0-2.02.0-2.1-2.11.6-1.8-1.9-1.9-2.1-2.1-2.12.12.12.02.12.0
Intermittent access total locomotion1.01.11.4-1.01.0-1.11.1-1.1-1.11.0-1.0-1.0-1.0-1.1-1.1-1.11.21.21.01.01.0
Intermittent access standard deviation2.72.84.2-1.21.5-1.61.6-1.6-1.71.3-1.5-1.5-1.5-1.7-1.7-1.82.12.11.91.81.9
Left kidney weight0.00.10.3-0.50.4-0.30.3-0.2-0.20.6-0.4-0.4-0.4-0.1-0.2-0.10.10.10.10.20.1
Right kidney weight1.54.14.8-2.02.0-2.02.0-2.0-2.02.1-2.1-2.1-2.1-2.0-2.0-2.02.02.02.02.22.0
Cocaine induced anxiety0.70.81.6-1.31.1-1.01.0-0.9-0.81.2-1.1-1.0-0.9-0.7-0.6-0.60.60.60.70.40.7
Post-drug Anxiety0.50.61.6-1.31.1-0.90.9-0.8-0.81.0-0.8-0.8-0.8-0.7-0.6-0.50.30.30.70.50.7
Baseline Anxiety0.10.10.40.00.2-0.20.1-0.3-0.3-0.1-0.0-0.0-0.2-0.4-0.5-0.50.30.30.60.60.6
Tail length3.19.512.0-2.52.9-3.02.9-3.1-3.12.7-3.0-3.0-3.0-3.2-3.3-3.23.33.33.33.53.2
Length with tail2.07.38.4-2.72.7-2.72.7-2.7-2.72.9-2.9-2.9-2.8-2.6-2.7-2.62.62.62.62.72.6
Length without tail0.10.20.9-0.90.7-0.50.6-0.4-0.40.9-0.7-0.6-0.6-0.3-0.1-0.2-0.0-0.0-0.00.00.0
Times rat made contact with spout0.30.30.70.8-0.70.6-0.60.60.6-0.80.60.60.60.50.40.4-0.3-0.3-0.3-0.4-0.3
Lifetime Intake0.10.10.2-0.10.2-0.30.3-0.3-0.30.2-0.2-0.2-0.2-0.3-0.4-0.30.50.50.30.30.3
Liver weight, left2.54.05.52.0-2.02.0-2.02.02.0-2.32.32.32.21.91.91.9-1.9-1.9-1.8-1.7-1.8
Liver weight, right1.72.83.41.4-1.61.6-1.61.71.7-1.81.81.81.81.71.71.7-1.7-1.7-1.8-1.4-1.7
Locomotor activity3.55.68.4-2.72.6-2.42.6-2.3-2.32.9-2.7-2.7-2.6-2.2-2.0-2.02.12.12.01.82.0
Locomotor testing distance2.13.54.7-2.12.0-1.92.0-1.8-1.82.2-2.1-2.1-2.0-1.7-1.7-1.71.81.81.71.51.7
Locomotor testing rearing0.00.00.10.3-0.10.0-0.0-0.0-0.1-0.1-0.1-0.1-0.1-0.1-0.0-0.20.30.30.40.20.4
Locomotion in novel chamber0.20.20.6-0.30.4-0.30.5-0.4-0.40.1-0.3-0.4-0.3-0.5-0.3-0.50.80.80.70.40.6
Locomotion in novel chamber post-restriction0.81.01.4-0.80.8-0.90.9-1.0-1.00.9-1.0-1.0-1.1-1.0-1.1-1.11.11.11.01.21.0
Fecal boli incidents, locomotor time 11.82.03.01.3-1.41.5-1.41.41.4-1.71.61.61.71.41.51.4-1.2-1.2-1.2-1.2-1.1
Change in fecal boli incidents, locomotor task0.20.21.0-0.20.3-0.30.3-0.3-0.31.0-0.8-0.8-0.7-0.2-0.2-0.30.30.30.30.10.4
Time >=10cm from walls, locomotor time 10.50.51.30.4-0.40.6-0.50.70.8-0.10.30.30.50.81.00.9-0.7-0.7-0.7-1.2-0.7
Bouts of movement, locomotor time 10.20.20.4-0.10.3-0.40.3-0.4-0.40.3-0.4-0.4-0.4-0.4-0.5-0.40.50.50.50.60.5
Total resting periods, locomotor time 10.30.30.5-0.30.4-0.50.5-0.5-0.50.5-0.5-0.6-0.5-0.5-0.6-0.50.50.50.50.70.5
Rest time, locomotor task time 10.30.30.7-0.50.6-0.70.6-0.6-0.60.5-0.5-0.5-0.5-0.6-0.7-0.50.40.40.30.80.4
Distance moved, locomotor task time 10.50.61.50.4-0.60.7-0.60.80.8-0.10.40.40.40.91.00.9-0.8-0.8-0.8-1.2-0.9
Vertical activity count, locomotor time 10.20.20.60.8-0.70.7-0.60.60.6-0.30.30.30.30.50.70.4-0.2-0.2-0.2-0.7-0.1
Time >=10cm from walls, locomotor time 21.61.72.31.5-1.41.5-1.41.41.4-1.21.21.21.31.41.51.3-0.9-0.9-1.0-1.3-1.0
Bouts of movement, locomotor time 20.60.61.9-1.41.0-1.01.0-0.8-0.81.0-0.8-0.8-0.8-0.7-0.8-0.60.40.40.30.60.3
Total resting periods, locomotor time 20.60.61.9-1.41.0-0.90.9-0.8-0.81.0-0.8-0.8-0.8-0.7-0.7-0.50.30.30.30.50.2
Rest time, locomotor task time 20.60.71.0-1.01.0-0.90.9-0.9-0.91.0-0.9-0.9-1.0-0.8-0.8-0.70.60.60.70.80.6
Distance moved, locomotor task time 20.80.91.41.2-1.11.0-1.01.01.0-1.11.11.01.10.90.90.9-0.8-0.8-0.8-0.8-0.8
Vertical activity count, locomotor time 20.91.01.91.4-1.21.1-1.11.01.0-1.31.11.11.20.90.90.8-0.6-0.6-0.7-0.6-0.5
Light reinforcement 16.511.813.6-3.73.7-3.73.6-3.6-3.63.4-3.5-3.4-3.4-3.5-3.5-3.33.13.13.23.23.2
Light reinforcement 22.33.03.8-2.01.9-1.91.8-1.8-1.81.8-1.8-1.8-1.8-1.8-1.7-1.71.51.51.51.41.6
Bone: marrow area0.20.40.70.4-0.60.6-0.60.60.6-0.30.50.50.50.70.60.6-0.8-0.8-0.8-0.4-0.8
Bone: maximum diameter0.81.43.0-1.51.3-1.31.3-1.2-1.11.7-1.5-1.4-1.4-1.0-1.0-0.90.80.80.80.90.8
Bone: maximum force1.22.12.71.3-1.41.5-1.51.61.6-0.91.21.21.21.61.61.6-1.6-1.6-1.5-1.4-1.5
Bone: maximum moment1.01.72.21.1-1.31.4-1.31.41.4-0.81.01.11.11.51.41.4-1.5-1.5-1.4-1.3-1.4
Mean time between licks in bursts4.25.96.9-2.22.5-2.42.4-2.5-2.52.1-2.3-2.3-2.4-2.5-2.4-2.52.62.62.62.22.6
Mean num. licks in bursts0.00.00.10.1-0.20.1-0.20.10.10.00.10.10.10.2-0.00.2-0.3-0.3-0.3-0.1-0.3
Cd content in liver0.30.30.90.3-0.40.5-0.40.60.6-0.30.40.40.40.60.90.6-0.5-0.5-0.5-0.9-0.5
Co content in liver0.50.60.8-0.70.8-0.80.8-0.8-0.80.6-0.7-0.7-0.7-0.8-0.6-0.80.90.90.90.90.9
Cu content in liver0.10.10.4-0.2-0.00.2-0.10.30.30.20.00.10.10.40.50.5-0.6-0.6-0.5-0.5-0.6
Fe content in liver0.00.00.30.10.0-0.10.1-0.2-0.2-0.1-0.0-0.0-0.0-0.2-0.2-0.30.30.30.30.50.3
K content in liver0.10.10.4-0.60.3-0.20.2-0.0-0.00.4-0.2-0.2-0.10.10.10.3-0.3-0.3-0.3-0.3-0.4
Mg content in liver0.10.10.3-0.60.3-0.10.20.00.00.5-0.2-0.2-0.10.20.30.3-0.4-0.4-0.3-0.4-0.4
Mn content in liver1.21.43.9-1.91.5-1.31.3-1.1-1.12.0-1.5-1.5-1.4-0.9-1.0-0.70.50.50.50.70.4
Na content in liver0.90.91.80.3-0.60.8-0.70.90.9-0.50.80.80.91.01.01.2-1.2-1.2-1.2-1.0-1.4
Rb content in liver0.40.41.1-0.0-0.40.4-0.40.60.6-0.00.30.40.40.70.80.8-0.9-0.9-1.0-1.0-0.9
Se content in liver0.20.30.7-0.60.5-0.60.5-0.6-0.60.5-0.5-0.5-0.5-0.5-0.6-0.50.40.40.20.90.3
Sr content in liver0.00.00.20.4-0.20.1-0.1-0.0-0.0-0.40.20.20.1-0.1-0.2-0.20.30.30.20.30.2
Zn content in liver1.61.73.2-0.50.9-1.11.1-1.3-1.30.5-0.9-1.0-1.0-1.5-1.4-1.61.81.81.61.71.7
Bone: minimum diameter0.00.00.2-0.10.00.0-0.00.10.10.4-0.2-0.2-0.20.20.10.2-0.3-0.3-0.3-0.0-0.3
Time in familiar zone, hab. session 12.42.33.3-1.11.4-1.41.3-1.5-1.51.2-1.4-1.4-1.4-1.5-1.7-1.61.61.61.81.81.7
Time in novel zone, hab. session 11.11.11.90.6-0.90.9-0.91.01.0-0.40.70.70.81.11.31.2-1.2-1.2-1.4-1.4-1.3
Total zone transitions, hab. session 11.11.63.7-1.91.6-1.51.5-1.3-1.31.6-1.4-1.3-1.3-1.1-1.1-0.90.70.70.80.70.8
Total locomotion distance, hab. session 11.41.94.9-2.21.8-1.61.6-1.4-1.42.0-1.6-1.6-1.6-1.1-1.1-0.90.60.60.80.90.7
Locomotion velocity, hab. session 11.82.65.9-2.42.0-1.91.9-1.7-1.62.0-1.8-1.7-1.7-1.5-1.4-1.21.01.01.11.21.1
Time in familiar zone, hab. session 26.46.78.6-1.92.4-2.52.4-2.6-2.62.0-2.3-2.4-2.4-2.7-2.9-2.82.82.82.92.92.8
Time in novel zone, hab. session 24.84.86.21.7-2.02.1-2.12.32.3-1.61.91.91.92.42.42.4-2.4-2.4-2.5-2.5-2.4
Total zone transitions, hab. session 20.20.31.0-1.00.4-0.20.20.10.10.30.00.10.10.30.50.6-0.8-0.8-0.7-0.8-0.8
Total locomotion distance, hab. session 21.21.64.1-2.01.7-1.51.5-1.4-1.31.4-1.3-1.2-1.3-1.2-1.1-0.90.70.70.80.90.8
Locomotion velocity, hab. session 21.21.64.9-2.21.8-1.61.6-1.4-1.31.5-1.3-1.2-1.3-1.2-1.1-0.90.60.60.70.80.7
Novel to familiar place preference ratio4.24.46.21.5-1.92.0-1.92.12.1-1.41.71.81.82.22.32.3-2.3-2.3-2.4-2.5-2.4
Novelty place preference2.52.63.91.1-1.41.5-1.51.61.6-1.01.31.31.41.71.81.8-1.9-1.9-2.0-1.9-1.9
Time in novel zone, NPP test2.93.04.21.3-1.61.6-1.61.71.8-1.11.41.51.51.91.91.9-2.0-2.0-2.0-2.0-2.0
Total zone transitions, NPP test0.10.11.0-1.00.6-0.40.5-0.2-0.20.3-0.1-0.1-0.1-0.10.00.2-0.3-0.3-0.2-0.4-0.2
Total locomotion distance, NPP test0.10.10.7-0.80.4-0.30.3-0.1-0.10.3-0.1-0.1-0.10.10.10.3-0.5-0.5-0.3-0.4-0.4
Locomotion velocity, NPP test0.10.21.2-1.10.7-0.60.6-0.4-0.40.6-0.4-0.3-0.3-0.2-0.2-0.0-0.2-0.2-0.0-0.1-0.1
Intraocular pressure0.10.20.50.7-0.30.2-0.20.00.0-0.70.30.30.3-0.1-0.2-0.30.50.50.50.30.5
Delta distance traveled before/after self-admin1.92.02.3-1.31.4-1.41.4-1.5-1.41.4-1.5-1.4-1.4-1.4-1.4-1.41.41.41.51.41.5
Delta ambulatory time before/after self-admin2.02.22.4-1.51.5-1.61.5-1.5-1.51.5-1.5-1.5-1.5-1.5-1.5-1.51.41.41.51.51.4
Parametrial fat weight0.40.81.3-0.40.6-0.80.7-0.8-0.80.7-0.8-0.9-0.8-0.9-0.9-0.91.11.11.01.11.0
Pavlov. Cond. lever latency0.10.10.30.5-0.20.2-0.20.10.1-0.40.20.20.2-0.00.1-0.20.40.40.4-0.10.3
Pavlov. Cond. magazine entry latency3.34.35.9-1.92.0-2.22.0-2.2-2.21.7-1.9-1.9-1.9-2.2-2.4-2.12.02.02.02.42.0
Pavlov. Cond. change in total contacts0.10.10.4-0.40.3-0.40.3-0.4-0.40.3-0.2-0.2-0.2-0.3-0.5-0.30.20.20.10.60.2
Pavlov. Cond. index score0.60.71.2-1.10.9-1.00.9-0.9-0.90.9-0.8-0.8-0.8-0.8-1.1-0.70.50.50.51.10.6
Pavlov. Cond. latency score0.60.71.5-1.20.9-1.00.9-0.9-0.91.1-0.9-0.8-0.9-0.8-1.0-0.60.40.40.41.00.5
Pavlov. Cond. lever contacts0.10.20.7-0.80.5-0.50.4-0.3-0.30.7-0.4-0.4-0.4-0.2-0.30.0-0.2-0.2-0.30.2-0.1
Pavlov. Cond. magazine entry number0.91.11.81.1-1.01.1-1.01.11.1-0.80.90.90.91.11.31.1-0.9-0.9-0.9-1.3-0.9
Pavlov. Cond. intertrial magazine entries0.10.10.30.00.2-0.20.2-0.3-0.3-0.1-0.1-0.1-0.2-0.4-0.3-0.50.60.60.60.40.5
Pavlov. Cond. lever-magazine prob. diff.1.01.21.9-1.31.1-1.31.1-1.2-1.21.1-1.1-1.1-1.1-1.1-1.3-1.00.80.80.81.40.9
Pavlov. Cond. response bias1.31.62.4-1.31.2-1.41.3-1.3-1.31.1-1.1-1.1-1.2-1.3-1.5-1.31.11.11.11.51.2
Pavlov. Cond. lever latency0.70.91.40.7-0.80.8-0.90.90.9-1.21.21.21.10.90.71.0-1.1-1.1-1.1-0.8-1.2
Pavlov. Cond. magazine entry latency0.40.50.8-0.50.6-0.70.6-0.7-0.70.8-0.8-0.8-0.8-0.7-0.9-0.70.70.70.70.80.8
Pavlov. Cond. change in total contacts0.60.91.3-0.70.8-0.80.9-0.8-0.81.0-1.1-1.1-1.1-0.9-0.7-1.01.11.11.10.71.1
Pavlov. Cond. index score0.81.01.4-0.60.8-0.90.9-0.9-0.91.1-1.2-1.2-1.1-0.9-0.9-1.01.11.11.20.91.2
Pavlov. Cond. latency score0.70.91.4-0.70.8-0.80.9-0.9-0.91.2-1.2-1.2-1.1-0.9-0.8-0.91.01.01.10.81.1
Pavlov. Cond. lever contacts0.60.91.4-0.50.7-0.70.8-0.8-0.80.9-1.0-1.0-1.0-0.9-0.7-1.01.11.11.10.91.2
Pavlov. Cond. magazine entry number0.70.91.20.7-0.80.9-0.80.90.9-1.11.11.11.10.91.00.9-0.9-0.9-0.9-1.0-1.0
Pavlov. Cond. intertrial magazine entries0.40.50.91.0-0.80.8-0.80.70.7-0.90.80.80.70.60.80.5-0.4-0.4-0.4-0.5-0.4
Pavlov. Cond. lever-magazine prob. diff.0.81.01.4-0.70.9-0.90.9-0.9-0.91.2-1.2-1.2-1.2-0.9-0.9-1.01.11.11.10.91.2
Pavlov. Cond. response bias1.62.23.1-0.91.3-1.31.3-1.4-1.41.4-1.6-1.6-1.6-1.5-1.3-1.61.71.71.71.51.8
Time in closed arm before self-admin0.60.71.50.0-0.40.6-0.50.70.8-0.30.60.60.60.90.91.0-1.1-1.1-1.2-1.1-1.2
Time in closed arm after self-admin0.00.00.0-0.00.1-0.10.1-0.1-0.10.0-0.1-0.1-0.1-0.1-0.1-0.20.20.20.10.20.1
Time in open arm before self-admin0.70.71.2-0.50.7-0.80.8-0.8-0.80.8-0.9-0.9-0.9-0.9-0.9-0.91.11.10.90.90.9
Time in open arm after self-admin0.80.91.00.9-0.91.0-1.01.01.0-0.90.91.00.91.01.00.9-1.0-1.0-0.9-0.9-0.9
Bone: periosteal estimation0.30.61.10.3-0.60.7-0.60.80.8-0.00.40.40.40.90.80.9-1.1-1.1-1.1-0.8-1.0
Bone: periosteal perimeter0.10.20.9-0.60.4-0.40.4-0.3-0.21.0-0.6-0.6-0.6-0.1-0.1-0.1-0.0-0.0-0.00.1-0.0
Bone: post-yield work0.60.81.01.0-1.01.0-1.00.90.9-0.90.90.90.90.90.80.9-0.8-0.8-0.8-0.6-0.8
Progressive ratio test 1 active lever presses0.10.10.30.5-0.40.3-0.40.30.2-0.50.40.40.30.20.20.1-0.1-0.1-0.2-0.0-0.2
Progressive ratio test 1 breakpoint0.20.20.40.6-0.50.4-0.50.40.4-0.60.50.50.40.30.30.3-0.2-0.2-0.3-0.1-0.3
Progressive ratio test 1 inactive lever presses0.00.00.1-0.10.1-0.20.2-0.2-0.20.1-0.1-0.1-0.2-0.2-0.2-0.20.10.10.00.20.0
Progressive ratio test 2 active lever presses0.10.20.50.10.1-0.20.2-0.3-0.30.0-0.2-0.2-0.2-0.4-0.4-0.40.70.70.50.50.5
Progressive ratio test 2 breakpoint0.20.20.5-0.20.3-0.40.4-0.4-0.40.3-0.4-0.4-0.4-0.5-0.5-0.50.70.70.50.50.5
Progressive ratio test 2 inactive lever presses0.00.00.1-0.20.2-0.20.3-0.2-0.20.2-0.2-0.2-0.2-0.2-0.3-0.10.30.30.20.10.2
Incentive Sensitization - Responses0.10.10.50.20.0-0.20.2-0.2-0.2-0.0-0.2-0.2-0.1-0.3-0.3-0.40.70.70.40.40.4
Incentive Sensitization - Breakpoint0.20.20.50.10.1-0.30.3-0.3-0.30.1-0.3-0.3-0.2-0.4-0.4-0.40.70.70.50.50.5
Sum of active levers in priming session hrs 5-60.00.00.00.0-0.0-0.00.0-0.0-0.0-0.00.00.00.10.00.00.00.00.0-0.0-0.0-0.0
Progressive ratio0.20.20.80.3-0.40.4-0.40.40.4-0.90.80.80.80.30.20.4-0.4-0.4-0.3-0.1-0.3
Food seeking constrained by brief footshock0.20.30.6-0.80.7-0.70.7-0.7-0.70.2-0.3-0.2-0.3-0.6-0.8-0.50.40.40.30.60.3
Seeking ratio, punishment vs. effort0.20.30.5-0.70.6-0.70.6-0.6-0.60.7-0.6-0.6-0.6-0.5-0.5-0.50.40.40.30.30.2
Retroperitoneal fat weight0.30.91.41.0-1.00.9-1.00.90.9-1.21.21.21.10.90.70.8-1.0-1.0-0.9-0.5-0.9
Reaction time number correct0.71.02.81.7-1.41.2-1.21.01.0-1.31.11.11.00.81.00.6-0.5-0.5-0.6-0.5-0.6
Reaction time mean minus median0.60.81.1-0.60.8-0.80.8-0.8-0.80.8-0.9-0.9-0.9-0.9-1.0-0.91.01.01.00.91.0
Reaction time mean minus median AUC0.00.10.3-0.40.2-0.10.1-0.00.00.5-0.3-0.3-0.30.1-0.10.1-0.3-0.3-0.1-0.1-0.2
Reaction time num false alarms0.20.21.21.1-0.80.7-0.70.50.5-0.40.40.30.30.40.30.2-0.1-0.1-0.2-0.2-0.1
Reaction time num false alarms AUC0.30.41.61.3-0.90.8-0.80.60.6-0.70.60.50.50.50.40.3-0.1-0.1-0.2-0.2-0.2
Reaction time trials correct on left0.71.02.81.7-1.41.2-1.21.01.0-1.31.11.11.00.81.00.6-0.5-0.5-0.6-0.5-0.6
Reaction time trials on left0.71.02.61.6-1.31.2-1.21.01.0-1.31.11.11.00.91.00.7-0.5-0.5-0.7-0.5-0.7
Reaction time mean0.00.00.1-0.10.10.1-0.00.10.20.3-0.1-0.1-0.10.20.20.2-0.3-0.3-0.0-0.3-0.1
Reaction time mean AUC0.00.10.2-0.0-0.00.2-0.10.20.20.2-0.1-0.0-0.00.30.20.3-0.3-0.3-0.1-0.4-0.2
Median of all reaction times0.20.30.60.3-0.40.6-0.50.60.6-0.10.30.40.40.70.70.7-0.8-0.8-0.6-0.8-0.7
Reaction time omissions0.30.30.6-0.80.7-0.60.7-0.6-0.60.7-0.7-0.6-0.6-0.5-0.5-0.50.50.50.40.30.4
Reaction time false alarm rate0.00.00.10.4-0.30.3-0.30.20.2-0.00.10.00.10.20.00.2-0.1-0.1-0.1-0.1-0.1
Reaction time premature initiation rate1.01.42.3-0.81.1-1.11.1-1.2-1.20.8-1.0-1.1-1.1-1.2-1.2-1.31.41.41.41.21.5
Reaction time premature initiations0.50.71.6-0.00.4-0.50.5-0.7-0.70.2-0.5-0.6-0.6-0.9-0.8-1.11.21.21.21.01.3
Std. dev. reaction times0.20.20.4-0.40.5-0.40.4-0.4-0.40.6-0.6-0.6-0.6-0.4-0.4-0.40.40.40.50.40.5
Reaction time trials completed0.71.02.61.6-1.31.2-1.21.01.0-1.31.11.11.00.91.00.7-0.5-0.5-0.7-0.5-0.7
Reaction time trials AUC0.71.02.91.7-1.41.2-1.21.01.0-1.41.11.11.00.80.90.6-0.4-0.4-0.6-0.4-0.6
Run reversals in cocaine runway, females0.40.40.6-0.70.7-0.70.7-0.7-0.70.7-0.7-0.7-0.7-0.6-0.8-0.60.50.50.50.70.5
Run reversals in cocaine runway, males1.61.62.2-1.51.4-1.41.4-1.3-1.31.3-1.2-1.2-1.3-1.3-1.3-1.21.01.01.01.21.0
Latency to leave start box in cocaine runway0.91.02.3-1.41.2-1.01.2-0.9-0.81.5-1.3-1.3-1.2-0.7-0.3-0.60.80.80.70.10.7
Latency to leave start box in cocaine runway, F0.20.21.1-0.70.3-0.00.30.20.20.7-0.4-0.4-0.20.30.90.5-0.2-0.2-0.4-1.0-0.5
Latency to leave start box in cocaine runway, M2.62.53.6-1.01.4-1.41.4-1.6-1.61.2-1.4-1.5-1.4-1.7-1.7-1.81.81.81.91.81.9
Std. dev. time between licks in bursts0.80.92.0-1.01.0-0.90.9-0.9-0.91.4-1.2-1.2-1.2-0.8-0.5-0.80.80.80.90.60.8
Total sessions with >9 infusions0.00.00.10.0-0.10.10.00.10.10.2-0.1-0.1-0.00.20.20.20.00.0-0.3-0.3-0.3
Short access day 1 total inactive lever presses0.10.10.1-0.30.2-0.30.3-0.3-0.30.1-0.2-0.2-0.2-0.3-0.4-0.30.30.30.10.30.1
Short access day 10 total inactive lever presses0.00.00.10.2-0.10.00.00.00.0-0.20.00.00.1-0.0-0.0-0.00.30.30.2-0.00.2
Short access day 1 total infusions0.20.20.5-0.70.6-0.60.6-0.5-0.50.7-0.6-0.6-0.5-0.4-0.5-0.30.30.30.20.20.2
Short access day 10 total infusions0.00.00.10.2-0.1-0.10.0-0.1-0.1-0.10.0-0.0-0.1-0.2-0.2-0.20.30.30.10.40.1
Short access total infusions0.00.00.00.0-0.0-0.00.1-0.0-0.00.1-0.0-0.0-0.00.0-0.00.00.10.1-0.1-0.1-0.1
Short access day 1 locomotion1.11.21.8-1.21.1-1.11.1-1.1-1.11.4-1.2-1.2-1.2-1.0-1.1-1.01.01.00.90.90.9
Short access day 10 total locomotion3.94.36.1-1.71.9-2.02.1-2.1-2.11.9-2.1-2.1-2.1-2.1-2.1-2.22.52.52.02.12.0
Short access total locomotion0.90.91.3-0.80.9-1.01.0-0.9-0.91.1-1.1-1.1-1.0-0.9-1.0-0.91.11.10.80.80.8
One hour access (0.3 mA shock)0.20.20.30.5-0.50.4-0.40.40.4-0.50.50.50.40.40.30.4-0.3-0.3-0.4-0.3-0.4
Compulsive drug intake1.31.31.90.8-1.01.1-1.01.21.2-0.81.01.01.11.21.21.3-1.2-1.2-1.3-1.4-1.3
One hour access (shock baseline)0.10.10.40.20.0-0.20.1-0.3-0.3-0.0-0.1-0.1-0.2-0.3-0.4-0.40.50.50.40.60.4
Social response proportion0.80.92.1-1.41.2-1.11.2-1.0-1.01.0-0.9-0.9-0.9-0.9-0.8-0.80.70.70.80.50.8
Social responses7.39.411.1-3.33.2-3.13.2-3.1-3.13.3-3.3-3.3-3.2-3.0-3.0-2.92.92.92.92.72.8
Social time0.50.71.20.5-0.60.8-0.70.80.8-1.00.91.01.00.81.00.9-0.9-0.9-0.7-1.1-0.8
Soleus weight9.527.829.75.2-5.45.4-5.45.45.4-4.95.25.25.25.45.35.3-5.2-5.2-5.3-5.0-5.2
Bone: stiffness3.04.75.52.0-2.22.2-2.22.32.3-1.72.02.02.02.32.22.3-2.3-2.3-2.3-2.2-2.3
Tibialis anterior weight1.34.45.12.1-2.32.1-2.22.12.1-2.02.12.12.12.12.02.1-2.1-2.1-2.2-1.8-2.1
Time to tail flick, vehicle, before self-admin0.50.51.5-1.20.9-0.80.9-0.7-0.71.0-0.8-0.8-0.8-0.6-0.6-0.50.40.40.30.40.4
Time to tail flick, vehicle, after self-admin0.10.20.40.20.1-0.20.1-0.3-0.3-0.2-0.0-0.0-0.1-0.5-0.5-0.50.40.40.60.70.6
Time to tail flick, test, before self-admin0.30.30.9-0.90.7-0.60.6-0.5-0.51.0-0.8-0.7-0.7-0.4-0.3-0.30.20.20.20.20.2
Time to tail flick, test, after self-admin0.30.30.9-1.00.7-0.60.7-0.6-0.60.7-0.6-0.6-0.6-0.5-0.6-0.50.30.30.30.50.3
Delta time to tail flick, vehicle, before/after SA0.50.51.71.3-0.90.8-0.90.60.6-1.20.90.90.80.50.40.3-0.3-0.3-0.1-0.2-0.2
Delta time to tail flick, test, before/after SA0.10.10.3-0.10.2-0.30.2-0.3-0.4-0.1-0.1-0.1-0.2-0.4-0.5-0.50.50.50.50.60.5
Tibia length0.92.73.4-1.41.6-1.61.6-1.6-1.61.5-1.6-1.6-1.6-1.6-1.6-1.61.71.71.81.71.8
Ambulatory time before self-admin0.40.40.60.5-0.60.6-0.60.70.7-0.40.50.50.60.70.80.8-0.7-0.7-0.8-0.8-0.8
Ambulatory time after self-admin0.30.30.5-0.60.6-0.60.6-0.6-0.60.7-0.7-0.7-0.6-0.6-0.5-0.50.60.60.50.50.5
Bone: tissue strength1.71.72.31.0-1.11.3-1.21.31.3-1.11.21.21.31.41.31.4-1.4-1.4-1.3-1.5-1.3
Total heroin consumption2.12.42.6-1.51.6-1.61.6-1.6-1.61.5-1.6-1.6-1.6-1.6-1.6-1.61.51.51.41.51.5
Bone: trabecular number0.71.22.7-1.61.3-1.21.2-1.0-1.01.6-1.3-1.3-1.3-0.9-1.0-0.70.60.60.50.70.5
Bone: trabecular spacing0.71.03.21.8-1.21.1-1.10.90.8-1.71.31.21.20.60.70.4-0.1-0.1-0.0-0.2-0.1
Bone: trabecular thickness0.50.62.5-1.40.7-0.40.6-0.0-0.01.6-0.8-0.8-0.70.30.30.5-0.7-0.7-0.8-0.9-0.7
Bone: trabecular tissue density1.72.43.51.5-1.51.6-1.51.61.6-1.91.81.81.81.51.51.5-1.4-1.4-1.3-1.3-1.3
Water consumed over 24 hours0.60.71.10.5-0.70.8-0.70.90.9-0.30.50.50.61.01.11.0-1.0-1.0-1.0-1.0-1.0
Number of responses in last shaping day0.10.10.4-0.20.2-0.30.4-0.3-0.30.4-0.4-0.4-0.4-0.3-0.4-0.40.60.60.30.40.3