Aox1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose isoform ratio XM_039084139.1 0.07 0.04 2.8e-05 0.03 0.04 0.04 0.03 4.4e-04 1.9e-05 8.7e-05 2.8e-04
2 Eye gene expression Aox1 0.4 0.18 5.1e-03 0.19 0.04 0.05 0.1 7.9e-04 7.0e-02 5.3e-02 1.4e-02
3 Adipose isoform ratio XR_594396.3 0.06 0.04 2.8e-06 0.06 0.06 0.05 0.05 5.7e-07 1.0e-06 1.8e-06 1.3e-06
4 BLA mRNA stability Aox1 0.08 0.05 1.9e-03 0.02 0.03 0.03 0.02 3.1e-02 9.4e-03 1.7e-02 3.6e-02
5 PL mRNA stability Aox1 0.03 0.02 3.3e-03 0.02 0.01 0.02 0.01 6.1e-03 1.9e-02 2.5e-03 2.4e-02
6 Adipose intron excision ratio chr9_59579773_59594097 0.04 0.03 4.5e-03 0.01 0.01 0 0.01 5.2e-02 7.2e-03 1.0e-01 2.4e-02
7 Liver intron excision ratio chr9_59651665_59655007 0.03 0.02 4.8e-03 0.01 0.01 0.01 0.01 2.6e-02 1.5e-02 3.0e-02 2.0e-02
8 LHb gene expression Aox1 0.47 0.16 3.5e-08 0.28 0.33 0.38 0.35 2.8e-07 9.8e-09 5.3e-10 4.0e-09
9 Adipose alternative TSS XM_039084139.1 0.05 0.03 3.8e-06 0.05 0.06 0.05 0.05 1.3e-06 1.0e-06 1.5e-06 1.9e-06
10 Adipose alternative TSS NM_019363.4 0.05 0.03 5.4e-06 0.05 0.05 0.05 0.05 1.9e-06 1.5e-06 2.1e-06 2.7e-06
11 IL gene expression Aox1 0.54 0.15 5.4e-08 0.28 0.17 0.24 0.26 2.1e-07 7.1e-05 1.7e-06 5.0e-07
12 Liver isoform ratio NM_019363.4 0.1 0.06 5.8e-07 0.05 0.06 0.06 0.05 5.8e-06 6.2e-07 9.7e-07 1.2e-06
13 Adipose gene expression Aox1 0.72 0.11 0.0e+00 0.38 0.54 0.54 0.55 5.5e-44 1.3e-71 6.7e-72 1.8e-72
14 PL intron excision ratio chr9_59603404_59607102 0.04 0.02 1.0e-03 0.02 0.03 0.03 0.02 5.1e-03 6.5e-04 7.6e-04 1.2e-03
15 BLA gene expression Aox1 0.69 0.11 0.0e+00 0.38 0.37 0.4 0.36 9.2e-22 9.9e-21 1.7e-22 2.2e-20
16 Brain intron excision ratio chr9_59603404_59607102 0.04 0.03 7.7e-04 0.02 0.03 0.03 0.02 6.3e-03 5.9e-04 7.1e-04 3.6e-03
17 Liver gene expression Aox1 0.66 0.11 0.0e+00 0.59 0.6 0.61 0.6 2.1e-81 1.0e-83 8.6e-85 1.6e-84
18 NAcc gene expression Aox1 0.77 0.09 0.0e+00 0.5 0.51 0.53 0.51 3.1e-67 7.0e-69 1.6e-71 1.3e-67
19 PL gene expression Aox1 0.76 0.06 0.0e+00 0.53 0.56 0.57 0.56 6.9e-68 2.5e-74 7.9e-77 3.1e-75
20 pVTA gene expression Aox1 0.59 0.14 0.0e+00 0.21 0.37 0.4 0.38 1.5e-09 8.6e-17 1.7e-18 2.2e-17
21 OFC gene expression Aox1 0.62 0.14 2.4e-10 0.22 0.32 0.29 0.28 5.1e-06 2.9e-08 1.5e-07 2.0e-07
22 Brain mRNA stability Aox1 0.15 0.08 1.3e-11 0.11 0.11 0.12 0.1 4.2e-10 2.7e-10 7.0e-11 7.5e-10
23 Brain gene expression Aox1 0.54 0.14 0.0e+00 0.33 0.4 0.39 0.39 3.0e-31 3.6e-39 2.0e-38 2.0e-38
24 Adipose intron excision ratio chr9_59611736_59612564 0.02 0.02 5.4e-03 0.02 0.02 0.01 0.02 3.9e-03 5.1e-03 7.7e-03 5.0e-03
25 Liver isoform ratio XR_594396.3 0.06 0.03 1.5e-05 0.04 0.04 0.03 0.04 3.3e-05 3.9e-05 2.8e-04 3.4e-05
26 Liver mRNA stability Aox1 0.03 0.02 4.8e-03 0.02 0.01 0.01 0.02 3.0e-03 3.6e-02 2.1e-02 5.0e-03
27 NAcc mRNA stability Aox1 0.03 0.02 2.0e-03 0 0.01 0.02 0 1.9e-01 4.9e-02 3.1e-03 1.3e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27
Bone: apparent density1.72.86.1-0.80.3-1.8-0.5-0.1-0.12.5-1.92.0-2.0-2.1-1.32.1-0.8-2.2-1.1-1.9-2.1-2.1-2.02.31.71.8-0.5-2.11.41.2
Area under the delay curve0.10.10.30.0-0.0-0.2-0.1-0.10.2-0.1-0.40.3-0.3-0.40.10.4-0.5-0.2-0.5-0.3-0.2-0.2-0.40.3-0.10.40.40.6-0.2-0.4
BMI with tail1.96.117.84.1-4.03.94.2-3.9-4.1-2.5-0.7-2.72.60.6-3.1-0.23.0-0.12.70.7-0.5-0.50.90.1-2.80.60.20.82.4-2.1
BMI without tail1.63.28.22.9-2.71.52.5-2.5-2.5-1.2-2.3-0.40.3-1.4-2.51.70.4-1.80.2-1.4-2.0-2.0-1.21.6-1.42.11.91.10.9-1.7
Body weight0.10.61.3-0.10.1-0.5-0.30.30.20.5-1.00.9-0.9-1.0-0.31.0-0.9-1.1-0.9-1.1-1.0-1.0-1.20.90.61.00.70.3-0.1-0.3
Weight adjusted by age0.91.02.2-0.20.1-0.60.0-0.5-0.51.5-1.20.9-0.9-1.2-1.21.3-0.0-1.4-0.3-1.0-1.3-1.4-1.31.40.81.1-0.9-1.21.1-1.0
Bone surface2.13.87.9-2.11.9-2.8-2.21.61.82.6-1.42.8-2.8-2.00.41.9-2.3-1.8-2.4-2.0-1.6-1.6-2.21.82.31.40.2-1.3-0.31.7
Bone volume1.73.06.2-1.61.2-2.4-1.50.91.02.5-1.62.4-2.4-2.0-0.31.9-1.7-1.9-1.8-1.9-1.8-1.7-2.01.92.01.5-0.1-1.60.41.4
Breakpoint value in progressive ratio session0.30.31.9-1.00.8-0.6-0.60.60.41.00.50.3-0.30.20.2-0.30.20.20.20.30.20.20.1-0.10.8-0.4-1.4-1.10.70.3
Number of licking bursts0.20.21.1-0.70.4-0.4-0.50.50.30.70.40.1-0.10.30.2-0.30.20.30.20.40.30.30.1-0.20.8-0.5-1.0-1.00.20.6
Context. condit. distance diff. score0.20.20.50.6-0.50.70.7-0.7-0.6-0.40.2-0.60.60.4-0.4-0.40.70.40.60.50.30.20.4-0.2-0.6-0.2-0.2-0.00.3-0.2
Locomotion velocity, session 10.50.51.61.2-1.01.11.0-0.9-0.8-1.30.0-0.90.90.3-0.3-0.30.50.30.50.40.20.30.5-0.4-1.1-0.10.81.0-0.1-1.1
Locomotion distance, session 10.70.93.21.5-1.31.01.6-1.8-1.7-0.3-0.8-0.50.5-0.4-1.60.51.0-0.60.8-0.2-0.7-0.8-0.20.7-0.90.80.0-0.21.3-0.7
Locomotion velocity, session 20.40.41.11.0-0.90.60.9-1.0-0.8-0.6-0.9-0.10.1-0.5-0.80.60.0-0.6-0.1-0.5-0.6-0.6-0.40.5-0.60.80.90.70.3-0.6
Locomotion distance, session 21.52.14.52.1-2.10.71.7-1.8-1.5-1.1-2.00.0-0.0-1.3-1.61.6-0.3-1.6-0.4-1.4-1.7-1.6-1.21.3-1.01.82.11.50.1-1.3
Locomotion velocity, session 30.50.51.41.2-1.10.61.0-1.0-1.0-0.5-1.0-0.10.1-0.6-1.00.70.1-0.7-0.0-0.6-0.8-0.8-0.50.6-0.50.90.80.60.4-0.9
Locomotion distance, session 30.20.20.5-0.10.2-0.5-0.30.10.20.3-0.60.6-0.6-0.6-0.00.6-0.6-0.6-0.7-0.7-0.6-0.6-0.60.50.20.60.50.2-0.30.2
Stereotopy head waving bouts, day 30.81.01.90.4-0.21.20.6-0.4-0.5-0.71.2-1.21.31.30.1-1.31.31.21.31.41.21.11.3-1.1-0.7-1.1-0.8-0.20.4-0.6
Stereotopy head waving duration, day 31.01.22.91.4-1.41.71.7-1.6-1.7-0.70.2-1.31.30.5-1.3-0.51.60.31.50.80.20.10.7-0.2-1.1-0.1-0.5-0.31.4-1.1
Locomotion velocity, session 70.70.82.31.2-1.01.51.2-1.0-1.1-1.10.4-1.21.20.7-0.6-0.71.10.61.10.80.50.40.7-0.5-1.1-0.3-0.00.50.6-0.9
Locomotion distance, session 70.20.31.60.9-0.90.40.6-0.3-0.3-1.1-0.3-0.40.4-0.0-0.00.1-0.2-0.0-0.0-0.1-0.10.00.1-0.2-0.70.11.11.3-0.7-0.4
Stereotopy head waving bouts, day 70.81.02.6-0.90.8-1.2-0.80.30.41.6-0.91.4-1.4-1.2-0.31.0-0.8-1.0-0.9-1.0-1.0-1.0-1.21.21.10.9-0.3-1.20.50.2
Stereotopy head waving duration, day 70.81.02.20.3-0.5-0.40.4-0.8-0.71.0-1.50.8-0.9-1.4-1.31.3-0.2-1.4-0.4-1.1-1.4-1.4-1.31.50.51.40.0-0.91.2-0.5
Locomotion velocity, session 80.30.40.90.6-0.50.20.6-0.8-0.70.2-0.90.3-0.3-0.7-1.00.80.0-0.8-0.2-0.7-0.8-0.9-0.80.9-0.00.90.3-0.10.6-0.4
Locomotion distance, session 80.20.41.01.0-0.70.40.8-1.0-0.8-0.4-0.7-0.10.1-0.5-0.80.50.1-0.60.0-0.5-0.6-0.6-0.30.5-0.70.70.70.40.3-0.6
Degree of sensitization distance0.30.30.70.7-0.90.80.8-0.6-0.7-0.70.2-0.80.80.4-0.3-0.40.70.40.70.50.30.30.6-0.4-0.5-0.3-0.00.20.3-0.3
Degree of sensitization stereotypy2.22.45.2-0.50.3-1.6-0.6-0.00.41.6-2.12.0-2.0-2.2-0.72.1-1.6-2.0-1.8-2.1-2.0-2.0-2.32.11.21.90.8-0.50.20.1
Conditioned locomotion0.91.02.7-0.40.5-1.3-0.80.60.90.1-0.91.2-1.2-1.10.51.1-1.7-0.9-1.6-1.3-0.8-0.7-1.00.70.30.81.61.0-1.40.5
Cocaine response after cond. corrected1.21.43.0-0.91.1-1.6-1.20.91.10.9-0.91.6-1.6-1.30.41.3-1.7-1.2-1.7-1.5-1.1-1.0-1.31.00.91.01.00.2-0.70.6
Cocaine response after cond. not corrected2.02.24.4-1.41.2-2.1-1.30.91.02.1-1.32.0-2.0-1.6-0.11.6-1.4-1.6-1.6-1.6-1.5-1.4-1.81.61.81.2-0.2-1.30.11.3
Cocaine response before conditioning0.91.18.1-0.7-0.1-0.50.1-0.2-0.61.9-0.10.2-0.2-0.0-1.0-0.01.0-0.20.90.3-0.1-0.3-0.20.61.3-0.1-2.4-2.91.71.5
Saline control response0.30.41.20.3-0.4-0.10.5-0.7-0.70.8-0.70.2-0.3-0.7-1.10.60.4-0.80.2-0.5-0.8-0.8-0.50.80.20.7-0.5-1.11.10.2
Bone: connectivity density1.62.55.5-0.1-0.1-1.10.0-0.6-0.51.9-2.11.7-1.7-2.1-1.72.1-0.6-2.2-1.0-1.9-2.2-2.3-2.12.31.12.1-0.0-1.61.60.6
Bone: cortical apparent density4.66.111.61.2-1.12.71.3-0.4-0.8-2.82.9-3.33.33.21.0-3.22.33.12.73.23.03.13.4-3.2-2.2-2.9-0.81.3-0.5-1.8
Bone: cortical area1.42.26.8-2.02.1-1.0-2.12.42.4-0.01.70.3-0.31.12.6-1.3-1.11.5-0.70.91.61.70.7-1.50.7-1.6-0.20.7-2.10.7
Bone: cortical porosity2.22.46.4-2.52.4-2.3-2.52.42.41.80.31.8-1.8-0.41.70.3-1.8-0.2-1.7-0.6-0.00.0-0.80.22.0-0.2-0.4-0.8-1.21.8
Bone: cortical porosity2.72.97.2-2.72.5-2.6-2.72.52.42.1-0.02.1-2.1-0.71.50.6-1.9-0.5-1.9-0.9-0.3-0.3-1.10.52.30.1-0.5-1.1-1.12.3
Bone: cortical thickness1.72.86.2-0.50.70.9-0.51.21.0-1.62.4-1.51.52.32.0-2.30.52.40.92.12.42.52.1-2.5-0.7-2.3-0.31.2-1.6-0.4
Bone: cortical thickness1.21.42.80.2-0.31.00.5-0.2-0.5-0.51.5-1.41.41.60.1-1.61.61.41.71.71.41.41.6-1.3-0.5-1.5-1.6-0.70.50.1
Bone: cortical tissue density4.45.810.81.4-1.22.81.5-0.6-0.9-2.92.7-3.33.33.00.8-3.02.32.92.73.02.82.93.3-3.0-2.2-2.7-0.71.3-0.4-1.9
Condit. Reinf. active minus inactive responses0.91.03.0-1.61.7-0.7-1.31.21.01.31.10.4-0.30.70.8-0.70.20.70.20.70.80.70.3-0.41.1-0.9-1.7-1.50.21.4
Condit. Reinf. active-inactive response ratio0.30.31.2-0.80.8-0.2-0.60.50.40.70.70.1-0.00.50.3-0.50.30.50.30.50.50.40.2-0.30.6-0.6-1.1-1.00.30.7
Condit. Reinf. active responses1.11.34.2-2.02.1-1.5-1.81.61.51.60.61.1-1.10.11.0-0.1-0.70.1-0.7-0.10.30.2-0.40.01.5-0.4-1.1-1.2-0.41.8
Condit. Reinf. inactive responses0.40.41.1-0.91.0-0.9-1.01.11.00.40.10.7-0.7-0.20.80.2-0.9-0.1-0.9-0.4-0.00.0-0.40.00.6-0.00.30.2-0.90.8
Incentive salience index mean1.41.75.4-2.32.3-1.3-1.91.71.51.91.20.8-0.80.71.2-0.7-0.20.7-0.20.60.80.70.1-0.41.7-1.0-2.0-1.90.01.9
Condit. Reinf. lever presses1.01.34.5-2.02.1-1.2-1.81.61.61.41.00.8-0.80.51.2-0.5-0.50.6-0.50.40.70.60.0-0.41.3-0.8-1.3-1.2-0.31.9
Condit. Reinf. active minus inactive responses1.51.95.6-2.11.7-2.2-1.81.51.42.4-0.31.7-1.7-0.80.50.7-1.1-0.7-1.1-0.8-0.5-0.5-1.10.92.00.2-1.1-1.9-0.11.7
Condit. Reinf. active-inactive response ratio1.31.35.3-2.01.8-1.3-1.51.41.12.00.90.7-0.70.30.6-0.50.00.30.10.40.50.40.1-0.11.6-0.8-2.1-2.30.41.2
Condit. Reinf. active responses1.21.74.7-2.01.6-2.2-1.81.71.52.0-0.21.6-1.5-0.60.80.5-1.2-0.5-1.1-0.6-0.3-0.3-0.80.61.90.0-0.9-1.5-0.51.9
Condit. Reinf. inactive responses0.20.20.6-0.40.0-0.7-0.50.50.50.2-0.40.5-0.5-0.40.40.4-0.8-0.3-0.7-0.5-0.3-0.2-0.40.20.50.20.40.3-0.70.7
Condit. Reinf. lever presses1.01.45.7-0.90.40.2-0.30.60.10.61.6-0.80.81.60.4-1.61.31.41.41.71.51.41.2-1.10.6-1.6-2.4-1.50.61.0
Condit. Reinf. lever reinforcers received1.21.64.3-2.11.6-2.1-1.81.71.52.1-0.01.5-1.4-0.50.80.4-1.0-0.4-0.9-0.5-0.2-0.2-0.70.52.0-0.1-1.1-1.6-0.42.0
Conditioned reinforcement - actives0.20.20.8-0.20.40.2-0.30.90.5-0.40.6-0.10.20.70.7-0.6-0.20.4-0.10.40.40.40.2-0.50.3-0.40.20.5-0.4-0.5
Conditioned reinforcement - inactives1.61.86.1-1.51.6-0.8-1.72.52.0-0.41.70.1-0.01.32.4-1.3-0.91.5-0.60.91.61.70.9-1.50.6-1.40.30.9-1.70.2
Conditioned locomotion0.20.31.91.0-1.40.70.9-0.2-0.8-0.7-0.3-0.50.50.5-0.60.10.4-0.30.3-0.1-0.4-0.3-0.20.10.40.20.20.40.20.7
Patch foraging indifference point 0 sec0.30.61.20.10.00.80.3-0.1-0.2-0.41.1-0.90.91.00.2-1.00.91.01.01.10.90.91.1-0.9-0.5-0.9-0.7-0.00.20.1
Patch foraging indifference point AUC0.50.61.8-1.31.3-0.8-1.21.11.10.70.90.3-0.30.51.0-0.6-0.20.7-0.20.50.80.70.3-0.50.8-0.8-0.8-0.7-0.40.7
Delay disc. indifference point, 0s delay1.51.65.62.0-2.11.62.1-2.4-2.1-1.0-0.7-1.11.1-0.1-1.70.21.4-0.41.10.1-0.6-0.60.20.4-1.40.6-0.00.51.5-1.4
Delay disc. indifference point, 16s delay0.40.41.0-0.70.9-0.8-0.7-0.00.51.0-0.40.9-0.9-0.80.00.7-0.5-0.3-0.7-0.4-0.3-0.4-0.60.60.10.5-0.5-0.30.5-0.4
Delay disc. indifference point, 2s delay1.01.13.81.7-1.91.11.8-1.9-1.8-0.6-1.0-0.70.6-0.4-1.70.50.9-0.60.8-0.2-0.7-0.7-0.30.6-0.80.80.20.11.1-1.0
Delay disc. indifference point, 24s delay0.10.10.4-0.40.4-0.3-0.3-0.10.30.20.10.2-0.2-0.20.30.1-0.10.2-0.20.10.20.20.1-0.1-0.2-0.1-0.30.10.2-0.6
Delay disc. indifference point, 4s delay0.40.41.81.2-1.40.91.1-1.1-1.0-0.8-0.4-0.60.60.1-0.8-0.10.50.00.50.1-0.1-0.10.00.1-0.60.20.30.50.3-0.1
Delay disc. indifference point, 8s delay0.90.92.7-0.91.0-1.3-1.30.91.30.4-0.61.3-1.3-1.00.90.9-1.7-0.6-1.6-1.0-0.5-0.4-0.80.50.30.60.90.7-1.10.3
Indifference point function ln k0.30.40.80.8-0.60.30.7-0.9-0.7-0.3-0.6-0.10.0-0.7-0.70.80.1-0.8-0.0-0.7-0.9-0.7-0.10.5-0.80.70.60.30.40.3
Indifference point function log k0.30.40.80.8-0.60.30.7-0.9-0.7-0.3-0.6-0.10.0-0.7-0.70.80.1-0.8-0.0-0.7-0.9-0.7-0.10.5-0.80.70.60.30.40.3
Patch foraging total patch changes 0 sec0.60.91.90.20.01.00.4-0.3-0.5-0.31.3-1.21.21.20.0-1.21.31.11.41.31.11.01.4-1.0-0.6-1.0-1.1-0.40.60.1
Patch foraging total patch changes 12 sec0.91.22.9-0.70.80.4-0.50.90.6-0.21.7-0.80.81.61.1-1.60.71.60.81.51.71.61.1-1.40.1-1.5-1.0-0.3-0.4-0.4
Patch foraging total patch changes 18 sec2.22.86.00.3-0.11.60.6-0.2-0.5-1.22.3-2.12.12.40.6-2.31.92.32.12.42.32.22.3-2.0-1.0-2.1-1.3-0.10.2-0.1
Patch foraging total patch changes 24 sec0.50.61.6-1.11.0-0.3-0.80.90.70.61.2-0.10.10.90.8-1.00.31.00.30.91.00.90.7-0.70.6-1.0-1.3-0.7-0.00.9
Patch foraging total patch changes 6 sec0.20.30.90.2-0.20.40.5-0.5-0.80.50.0-0.20.20.2-0.8-0.20.90.00.70.30.0-0.2-0.10.30.30.1-0.9-1.01.0-0.3
Patch foraging time to switch 0 sec0.30.43.10.9-1.00.91.0-0.8-1.0-0.3-0.6-0.40.4-0.1-1.00.10.6-0.30.5-0.0-0.4-0.4-0.30.3-0.20.40.00.10.7-1.8
Patch foraging water rate 0 sec0.20.32.1-0.70.9-0.8-0.90.60.90.30.30.5-0.5-0.20.70.2-0.7-0.0-0.6-0.30.00.10.1-0.1-0.0-0.10.30.1-0.71.4
Patch foraging water rate 12 sec0.81.33.10.8-1.00.00.9-1.3-1.20.7-1.50.5-0.5-1.3-1.81.40.2-1.5-0.1-1.2-1.6-1.6-1.01.50.01.5-0.1-0.91.30.6
Patch foraging water rate 18 sec0.30.42.6-0.70.4-0.6-0.30.20.11.00.30.2-0.2-0.0-0.2-0.00.3-0.00.30.1-0.0-0.00.30.10.5-0.2-1.3-1.60.71.6
Patch foraging water rate 24 sec0.81.12.90.5-0.9-0.60.4-0.7-0.60.5-1.60.8-0.8-1.4-1.21.6-0.5-1.6-0.6-1.4-1.7-1.6-1.21.40.41.50.4-0.20.70.4
Patch foraging water rate 6 sec0.20.20.50.5-0.60.10.5-0.7-0.5-0.0-0.60.1-0.1-0.6-0.70.70.0-0.6-0.1-0.5-0.7-0.6-0.30.6-0.30.70.50.10.30.3
Seeking ratio, delayed vs. immediate footshock1.51.84.7-0.10.3-1.1-0.2-0.8-0.01.2-1.81.5-1.5-2.2-0.92.1-1.0-1.6-1.3-1.7-1.6-1.7-1.71.8-0.11.80.50.10.6-1.4
Distance traveled before self-admin1.51.64.2-1.51.3-2.0-1.51.21.21.8-0.81.7-1.7-1.30.41.2-1.4-1.2-1.4-1.2-1.0-1.0-1.41.01.60.7-0.3-0.8-0.20.3
Distance traveled after self-admin0.40.41.1-0.40.6-0.7-0.70.50.70.1-0.40.7-0.7-0.60.50.6-1.1-0.5-1.0-0.7-0.4-0.4-0.70.40.20.50.70.9-0.7-0.7
Extensor digitorum longus weight0.83.19.12.8-2.52.62.5-2.1-2.1-2.8-0.1-2.12.10.7-1.0-0.51.40.51.40.70.30.41.0-0.7-2.3-0.11.42.10.3-3.0
Bone: elastic displacement0.70.73.30.6-0.70.61.0-1.2-1.30.6-0.0-0.50.50.1-1.4-0.01.4-0.21.20.3-0.2-0.40.20.4-0.10.1-1.5-1.51.80.0
Bone: elastic work0.10.10.6-0.30.2-0.3-0.10.1-0.00.60.00.2-0.2-0.0-0.20.10.2-0.10.10.0-0.1-0.1-0.10.20.40.0-0.8-0.80.60.3
Bone: endosteal estimation1.32.97.3-2.62.4-2.7-2.62.32.22.4-0.32.2-2.2-1.01.20.8-1.9-0.7-1.8-1.0-0.5-0.5-1.30.82.30.3-0.6-1.4-0.72.0
Bone: endosteal perimeter1.43.07.1-2.22.0-2.7-2.21.81.92.3-0.92.4-2.4-1.50.81.3-2.1-1.3-2.1-1.6-1.1-1.0-1.71.32.00.9-0.0-1.0-0.72.0
Epididymis fat weight0.92.27.2-0.71.1-1.3-1.51.51.7-0.3-1.01.5-1.5-1.21.41.2-2.6-0.9-2.4-1.6-0.8-0.7-1.40.50.50.92.72.1-2.4-0.4
Delta time in closed arm before/after self-admin0.20.10.4-0.70.4-0.5-0.60.70.60.30.40.2-0.20.20.6-0.3-0.20.3-0.20.20.30.30.1-0.30.5-0.4-0.5-0.1-0.10.1
Delta time in open arm before/after self-admin2.12.05.6-2.42.2-2.4-2.32.12.11.80.21.6-1.6-0.51.40.3-1.6-0.3-1.4-0.6-0.1-0.0-0.70.21.9-0.2-0.4-1.0-1.01.5
Diff in mean of infusions in LGA sessions1.01.13.5-0.50.3-1.0-0.2-0.3-0.31.9-1.01.0-1.0-1.2-1.11.20.0-1.3-0.2-0.9-1.2-1.3-1.11.41.10.9-1.3-1.71.40.0
Delay discount exponential model param0.10.10.30.1-0.00.30.20.0-0.2-0.10.5-0.40.40.4-0.1-0.40.50.20.60.40.30.20.5-0.3-0.1-0.4-0.3-0.40.10.3
Extinction: sum of active levers before priming0.40.41.1-0.20.0-0.5-0.0-0.2-0.21.1-0.70.6-0.6-0.7-0.70.70.0-0.8-0.1-0.6-0.8-0.8-0.70.80.60.6-0.8-0.91.0-0.3
Active lever presses in extinction session 60.20.20.7-0.50.5-0.4-0.70.80.8-0.10.10.3-0.30.00.8-0.0-0.70.1-0.7-0.10.20.2-0.1-0.20.1-0.10.40.8-0.70.2
Bone: final force0.81.44.3-1.91.8-1.4-2.02.12.00.60.70.9-0.80.21.9-0.4-1.30.6-1.10.10.70.8-0.0-0.61.1-0.8-0.10.1-1.50.8
Bone: final moment0.50.82.5-1.41.3-1.0-1.41.61.40.50.80.5-0.40.51.4-0.6-0.70.6-0.50.40.80.80.2-0.60.9-0.8-0.5-0.2-0.90.6
Food consumed during 24 hour testing period1.01.22.41.3-1.31.61.5-1.3-1.4-1.20.5-1.51.50.8-0.7-0.71.50.71.51.00.50.61.2-0.7-1.3-0.6-0.40.20.7-1.0
Glucose0.60.92.21.5-1.51.41.4-1.1-1.2-1.40.0-1.31.20.6-0.6-0.50.90.51.00.60.40.40.5-0.5-1.0-0.20.50.90.1-1.2
Heart weight0.70.92.4-0.00.0-0.30.2-0.8-0.61.4-1.10.8-0.8-1.2-1.31.20.2-1.3-0.2-1.0-1.3-1.4-0.91.40.31.1-0.8-1.31.6-0.2
Delay discount hyperbolic model param0.10.10.2-0.20.30.0-0.10.30.00.10.5-0.20.20.30.1-0.30.30.20.40.30.20.20.5-0.3-0.0-0.3-0.3-0.50.10.4
Intermittent access intake day 1-15 change1.21.24.90.8-1.00.91.3-1.8-1.60.6-0.4-0.50.5-0.3-1.70.11.6-0.41.30.2-0.5-0.60.10.6-0.50.4-1.6-1.52.2-1.9
Intermittent access intake escalation1.11.04.70.4-0.60.70.9-1.4-1.30.9-0.1-0.50.5-0.1-1.4-0.21.5-0.11.30.4-0.2-0.30.30.4-0.20.1-1.9-1.82.2-1.7
Intermittent access intake escalation 20.90.93.20.0-0.2-0.00.5-1.1-0.91.4-0.70.3-0.3-0.8-1.40.60.8-0.80.5-0.4-0.8-1.0-0.51.00.20.6-1.5-1.71.8-1.4
Intermitt. access day 1 inactive lever presses1.51.63.50.5-0.61.20.50.1-0.2-1.41.6-1.61.61.70.7-1.71.01.81.31.81.81.91.8-1.7-0.9-1.50.00.5-0.4-0.6
Intermitt. access day 15 inactive lever presses0.10.10.5-0.30.0-0.2-0.20.40.10.30.30.0-0.00.30.1-0.20.20.10.20.20.20.10.1-0.10.5-0.3-0.7-0.50.20.7
Intermitt. access escalation Index0.90.83.70.20.20.4-0.30.50.7-1.50.5-0.40.40.51.2-0.6-0.70.8-0.50.40.80.90.6-0.9-1.0-0.41.81.9-1.70.1
Intermittent access day 1 total infusions0.50.61.8-0.40.60.2-0.51.30.7-0.71.3-0.40.41.41.1-0.9-0.11.00.00.81.01.00.7-1.00.1-0.90.10.9-0.60.3
Intermittent access day 15 total infusions0.80.92.7-0.20.20.80.10.5-0.2-0.11.5-0.90.91.70.2-1.21.21.11.11.31.00.91.0-0.90.2-1.0-1.4-0.50.9-0.8
Intermittent access terminal intake (last 3 days)1.01.13.3-0.0-0.10.80.40.4-0.5-0.11.5-1.11.11.8-0.0-1.41.51.11.41.51.11.01.2-0.90.4-1.1-1.7-1.01.10.2
Intermittent access total infusions0.91.03.7-0.30.30.6-0.11.10.2-0.51.7-0.90.91.90.8-1.40.81.30.81.41.31.21.2-1.20.3-1.2-0.90.00.10.5
Intermittent access day 1 locomotion2.12.26.3-0.50.50.6-0.51.50.8-1.12.4-1.31.32.51.6-2.10.62.10.92.02.12.11.9-2.00.0-1.9-0.60.7-0.61.0
Intermittent access day 15 total locomotion0.70.72.0-0.50.30.3-0.20.70.3-0.11.4-0.70.71.40.6-1.30.71.20.81.31.21.21.1-1.10.2-1.2-1.1-0.30.3-0.0
Intermittent access total locomotion0.70.82.8-0.1-0.00.6-0.10.90.3-0.81.4-0.90.91.70.8-1.30.51.20.61.21.21.21.1-1.20.1-1.1-0.30.6-0.20.7
Intermittent access standard deviation1.31.42.90.1-0.11.10.5-0.1-0.6-0.11.6-1.31.31.6-0.1-1.51.71.41.71.71.41.31.6-1.1-0.4-1.3-1.7-1.01.0-0.3
Left kidney weight0.00.00.3-0.10.1-0.0-0.1-0.00.00.2-0.20.2-0.2-0.2-0.10.0-0.1-0.1-0.1-0.0-0.0-0.1-0.10.2-0.00.1-0.1-0.00.3-0.6
Right kidney weight0.10.30.7-0.10.1-0.4-0.1-0.20.00.6-0.80.7-0.7-0.9-0.40.7-0.4-0.7-0.5-0.7-0.7-0.7-0.70.80.20.7-0.1-0.20.40.2
Cocaine induced anxiety0.20.20.80.8-0.90.30.6-0.6-0.5-0.5-0.7-0.10.1-0.5-0.50.4-0.1-0.4-0.1-0.4-0.5-0.4-0.20.3-0.40.50.70.3-0.10.2
Post-drug Anxiety0.60.71.50.8-0.50.20.7-1.2-0.90.2-1.20.3-0.3-1.2-1.21.20.0-1.0-0.2-0.9-1.0-1.1-0.71.0-0.71.10.6-0.30.50.8
Baseline Anxiety0.30.31.7-1.01.3-0.8-0.90.60.80.90.20.7-0.6-0.30.50.2-0.5-0.1-0.5-0.20.0-0.0-0.20.10.30.0-0.3-0.5-0.10.2
Tail length3.19.421.6-4.24.2-4.7-4.64.44.42.9-0.84.0-3.9-1.92.91.7-4.4-1.4-4.2-2.3-0.9-0.8-2.61.13.60.81.2-0.2-3.11.6
Length with tail3.111.428.1-4.94.8-5.2-5.34.95.03.4-0.64.4-4.3-1.93.31.6-4.7-1.3-4.5-2.3-0.8-0.8-2.71.14.00.60.8-0.4-3.01.8
Length without tail1.02.27.0-2.62.5-2.0-2.52.42.41.51.01.2-1.20.32.0-0.5-1.30.6-1.10.20.80.8-0.1-0.51.7-0.9-1.0-0.6-1.01.2
Times rat made contact with spout0.80.92.41.5-1.51.31.4-1.3-1.3-1.30.0-1.31.20.4-0.7-0.31.00.31.00.50.10.30.8-0.4-1.2-0.20.40.70.3-1.4
Lifetime Intake0.70.82.90.1-0.00.80.20.60.0-0.81.4-1.01.01.70.6-1.20.71.10.81.21.11.11.1-1.1-0.1-1.0-0.60.40.10.3
Liver weight, left0.81.33.3-0.0-0.2-1.1-0.50.60.60.1-1.61.3-1.3-1.30.11.4-1.7-1.3-1.7-1.6-1.2-1.1-1.61.10.81.31.81.1-1.1-0.4
Liver weight, right1.62.66.9-1.71.3-2.3-1.41.00.92.6-1.22.2-2.1-1.5-0.31.5-1.3-1.5-1.4-1.5-1.4-1.4-1.91.72.31.1-0.8-2.00.42.0
Locomotor activity0.20.31.00.9-0.80.80.7-0.6-0.6-1.00.1-0.70.70.3-0.2-0.30.40.30.50.30.30.30.5-0.4-0.9-0.10.60.8-0.30.4
Locomotor testing distance0.71.23.01.6-1.71.61.7-1.6-1.7-1.10.2-1.51.50.6-1.1-0.51.50.51.50.80.40.40.9-0.4-1.3-0.2-0.10.10.70.3
Locomotor testing rearing0.10.11.20.4-0.60.20.4-0.3-0.3-0.4-0.2-0.30.3-0.0-0.10.10.00.00.1-0.00.00.10.2-0.1-0.3-0.00.30.3-0.21.1
Locomotion in novel chamber2.83.413.81.5-1.42.22.3-2.5-2.80.30.5-1.71.70.8-2.5-0.73.20.32.81.30.1-0.11.20.1-1.2-0.1-2.7-2.13.7-1.6
Locomotion in novel chamber post-restriction0.50.61.5-0.70.8-0.3-0.4-0.10.30.51.1-0.40.40.40.4-0.60.61.10.71.01.21.11.2-0.7-0.6-0.9-1.0-1.10.40.0
Fecal boli incidents, locomotor time 10.30.41.8-1.00.8-0.8-0.80.80.70.90.20.5-0.50.30.4-0.4-0.20.4-0.20.30.50.4-0.50.01.3-0.4-0.9-0.7-0.1-0.2
Change in fecal boli incidents, locomotor task0.20.20.80.3-0.10.50.2-0.4-0.2-0.50.2-0.40.30.10.1-0.20.20.30.20.20.10.10.5-0.3-0.9-0.10.00.90.4-0.8
Time >=10cm from walls, locomotor time 10.50.51.6-0.70.8-0.4-0.91.11.1-0.30.60.1-0.10.51.2-0.6-0.70.7-0.50.40.80.90.2-0.70.4-0.70.20.6-1.20.1
Bouts of movement, locomotor time 12.32.56.8-1.72.00.0-1.31.61.30.42.6-0.60.72.11.7-2.20.82.20.92.02.32.11.7-1.80.4-2.1-2.0-1.0-0.20.3
Total resting periods, locomotor time 13.43.710.3-1.41.90.7-1.01.41.1-0.33.2-1.31.42.71.9-2.81.22.91.42.72.92.82.4-2.5-0.3-2.6-1.8-0.6-0.40.2
Rest time, locomotor task time 14.14.510.6-0.21.31.9-0.31.20.8-1.93.2-2.02.03.12.1-3.11.23.11.32.73.13.02.6-2.9-1.4-2.5-0.21.4-1.1-1.4
Distance moved, locomotor task time 13.13.47.4-0.5-0.2-2.4-0.80.20.61.3-2.62.2-2.2-2.7-0.52.7-2.3-2.3-2.2-2.5-2.2-2.0-2.42.11.32.01.3-0.1-0.71.4
Vertical activity count, locomotor time 11.41.53.70.1-0.7-1.2-0.1-0.20.10.5-1.91.3-1.3-1.7-0.61.7-1.3-1.7-1.3-1.7-1.7-1.5-1.61.50.81.41.00.2-0.40.7
Time >=10cm from walls, locomotor time 21.11.22.81.4-1.60.41.0-1.1-0.9-0.9-1.50.1-0.1-1.1-0.91.2-0.5-1.3-0.5-1.3-1.4-1.3-0.80.9-0.71.31.71.4-0.2-1.3
Bouts of movement, locomotor time 20.20.21.10.30.10.20.4-0.9-0.50.3-0.30.1-0.1-0.6-0.70.50.4-0.10.1-0.2-0.3-0.40.00.4-0.90.5-0.3-0.41.00.1
Total resting periods, locomotor time 20.20.20.8-0.10.50.30.1-0.5-0.20.20.4-0.20.20.0-0.2-0.10.60.50.40.50.40.30.6-0.1-0.8-0.2-0.7-0.50.90.3
Rest time, locomotor task time 23.54.19.9-0.81.51.1-0.91.61.3-1.43.1-1.61.62.92.4-3.00.73.11.02.63.13.02.4-2.8-0.6-2.7-0.40.9-1.5-0.1
Distance moved, locomotor task time 21.21.43.80.3-0.7-1.00.2-0.6-0.30.6-1.81.0-1.1-1.9-0.91.9-0.9-1.8-1.0-1.7-1.8-1.7-1.21.50.21.50.8-0.10.10.0
Vertical activity count, locomotor time 22.02.15.12.3-2.21.42.1-2.3-2.2-0.8-1.6-0.50.5-1.0-2.21.10.8-1.50.5-1.0-1.6-1.6-0.61.2-1.21.60.90.51.3-1.6
Light reinforcement 12.24.010.93.2-3.33.13.1-2.9-2.7-2.7-0.2-2.42.40.8-1.7-0.62.00.52.00.90.30.31.1-0.6-2.4-0.00.81.61.0-2.6
Light reinforcement 20.30.42.90.4-0.30.10.2-0.3-0.2-0.1-0.80.4-0.4-0.6-0.40.6-0.4-0.6-0.6-0.7-0.6-0.7-0.80.6-0.00.80.80.5-0.0-1.7
Bone: marrow area1.32.87.3-2.72.4-2.7-2.62.32.32.4-0.12.1-2.1-0.81.30.6-1.8-0.6-1.7-0.9-0.3-0.3-1.10.62.20.1-0.7-1.4-0.82.1
Bone: maximum diameter1.73.19.5-2.82.8-2.2-3.03.03.11.01.21.3-1.30.42.8-0.6-1.90.8-1.60.11.01.1-0.0-0.91.6-1.1-0.20.1-2.21.5
Bone: maximum force0.50.82.1-1.41.3-1.4-1.41.31.31.2-0.01.1-1.1-0.40.80.3-1.0-0.2-1.0-0.4-0.1-0.1-0.60.31.10.0-0.2-0.6-0.50.9
Bone: maximum moment0.20.31.0-0.90.7-0.8-0.80.70.61.00.00.6-0.6-0.20.20.1-0.3-0.2-0.3-0.2-0.1-0.1-0.30.30.8-0.0-0.6-0.80.10.6
Mean time between licks in bursts0.71.07.11.2-0.70.80.5-0.3-0.0-2.0-0.3-0.50.4-0.10.50.1-0.70.0-0.5-0.3-0.00.10.1-0.4-1.30.32.42.7-1.4-1.7
Mean num. licks in bursts0.91.13.41.7-1.41.41.4-1.3-1.1-1.8-0.1-1.11.10.2-0.5-0.10.50.10.60.2-0.00.10.6-0.4-1.70.11.31.6-0.1-1.6
Cd content in liver0.20.20.4-0.1-0.0-0.5-0.20.00.10.5-0.60.5-0.5-0.6-0.20.6-0.4-0.6-0.4-0.6-0.5-0.5-0.60.60.30.50.2-0.2-0.00.4
Co content in liver0.30.31.9-0.20.10.20.2-0.2-0.40.60.5-0.30.30.4-0.4-0.40.90.30.80.60.30.20.4-0.10.1-0.4-1.4-1.30.90.3
Cu content in liver0.40.51.4-1.01.0-0.7-1.11.11.20.10.70.3-0.30.41.2-0.5-0.60.5-0.50.20.60.60.2-0.60.5-0.6-0.00.3-1.00.4
Fe content in liver0.40.52.9-0.50.2-0.6-0.1-0.2-0.31.4-0.30.5-0.5-0.4-0.80.40.4-0.50.2-0.2-0.5-0.6-0.40.80.80.3-1.4-1.71.31.0
K content in liver0.70.72.1-1.20.9-1.0-1.31.51.40.10.70.3-0.30.51.4-0.6-0.80.6-0.60.30.70.80.3-0.70.6-0.8-0.10.3-1.40.9
Mg content in liver0.00.00.2-0.2-0.0-0.4-0.10.10.10.3-0.10.2-0.2-0.1-0.00.1-0.1-0.1-0.1-0.1-0.1-0.1-0.20.10.30.0-0.2-0.2-0.00.4
Mn content in liver2.12.34.60.5-0.31.70.9-0.5-0.7-1.12.0-2.02.02.10.2-2.12.01.92.02.11.81.72.0-1.8-1.1-1.8-1.4-0.10.5-0.7
Na content in liver0.91.02.9-1.71.5-1.1-1.61.71.60.80.80.7-0.60.41.4-0.5-0.80.5-0.60.20.70.70.1-0.51.0-0.8-0.6-0.4-0.91.2
Rb content in liver1.31.63.3-0.30.3-1.3-0.60.30.60.7-1.61.6-1.6-1.7-0.21.7-1.6-1.6-1.7-1.8-1.6-1.5-1.81.50.71.51.40.3-0.50.4
Se content in liver0.10.10.30.1-0.20.00.3-0.3-0.40.10.1-0.20.20.2-0.3-0.20.50.10.40.20.10.00.2-0.0-0.0-0.1-0.6-0.40.50.3
Sr content in liver1.51.42.80.10.10.7-0.20.70.6-1.61.4-1.11.11.51.4-1.50.11.60.31.31.61.71.4-1.7-0.8-1.40.71.5-1.50.3
Zn content in liver0.20.21.40.6-0.40.40.3-0.2-0.1-1.10.2-0.50.50.30.3-0.3-0.10.40.00.20.30.40.3-0.5-0.7-0.20.81.2-0.8-0.2
Bone: minimum diameter1.01.95.8-2.22.3-1.4-2.22.42.30.71.30.8-0.70.72.2-0.8-1.21.0-0.90.51.11.20.3-0.91.1-1.2-0.5-0.1-1.61.2
Time in familiar zone, hab. session 11.31.35.00.3-0.20.00.6-1.4-1.11.4-1.10.6-0.6-1.3-1.81.10.6-1.30.2-0.8-1.4-1.5-0.81.50.01.4-0.7-1.72.2-0.3
Time in novel zone, hab. session 11.11.13.9-0.40.3-0.1-0.71.41.1-1.11.1-0.50.51.31.7-1.1-0.51.3-0.20.81.31.50.7-1.40.1-1.30.51.5-2.00.2
Total zone transitions, hab. session 10.40.61.1-0.30.1-0.9-0.30.00.10.9-0.90.9-0.9-0.9-0.41.0-0.6-1.1-0.7-1.0-1.0-1.0-0.91.00.60.80.1-0.60.10.6
Total locomotion distance, hab. session 10.50.82.8-1.51.3-1.3-1.10.90.81.70.30.9-0.9-0.20.30.2-0.3-0.3-0.3-0.2-0.2-0.2-0.20.31.2-0.1-1.3-1.70.21.2
Locomotion velocity, hab. session 10.40.62.0-1.41.3-1.2-1.21.00.91.30.40.8-0.8-0.10.50.1-0.4-0.2-0.4-0.2-0.0-0.0-0.10.11.1-0.2-1.0-1.2-0.11.0
Time in familiar zone, hab. session 20.80.93.0-0.30.10.60.2-0.0-0.30.31.2-0.90.91.10.0-1.21.31.11.31.31.11.01.1-0.80.0-1.1-1.7-1.20.8-0.2
Time in novel zone, hab. session 20.40.42.00.9-0.70.30.6-0.5-0.3-0.9-0.7-0.0-0.0-0.5-0.30.6-0.4-0.5-0.5-0.6-0.6-0.5-0.40.3-0.70.71.41.3-0.4-0.3
Total zone transitions, hab. session 20.70.83.21.6-1.80.71.5-1.5-1.5-0.7-1.1-0.40.4-0.5-1.40.70.5-0.80.4-0.5-0.8-0.8-0.40.7-0.60.80.70.40.4-0.5
Total locomotion distance, hab. session 20.60.82.11.3-1.40.51.3-1.4-1.3-0.4-1.1-0.20.2-0.7-1.40.80.4-0.90.2-0.6-1.0-0.9-0.40.8-0.60.90.60.10.6-0.8
Locomotion velocity, hab. session 20.40.61.71.2-1.30.51.2-1.2-1.1-0.5-0.9-0.30.2-0.6-1.10.60.3-0.70.2-0.5-0.8-0.7-0.30.6-0.60.80.60.30.4-0.8
Novel to familiar place preference ratio0.40.41.30.9-1.10.20.8-0.8-0.8-0.3-1.00.0-0.0-0.6-0.90.70.0-0.7-0.1-0.6-0.8-0.7-0.60.7-0.20.70.60.30.20.1
Novelty place preference0.30.31.20.9-1.10.20.8-0.7-0.8-0.3-0.8-0.10.1-0.4-0.90.60.1-0.60.1-0.4-0.6-0.6-0.50.6-0.10.60.40.20.20.1
Time in novel zone, NPP test0.40.51.61.0-1.30.31.0-1.0-1.0-0.2-1.0-0.10.1-0.5-1.10.70.2-0.70.2-0.5-0.8-0.8-0.60.7-0.10.70.30.00.50.1
Total zone transitions, NPP test0.00.10.20.1-0.3-0.10.2-0.3-0.30.3-0.40.1-0.1-0.2-0.50.30.1-0.30.1-0.2-0.3-0.3-0.30.40.10.3-0.2-0.40.20.0
Total locomotion distance, NPP test0.30.42.10.3-0.40.30.7-0.9-0.90.60.1-0.40.40.0-1.0-0.01.1-0.11.00.3-0.1-0.20.30.3-0.2-0.0-1.3-1.41.30.1
Locomotion velocity, NPP test0.30.51.60.2-0.30.50.6-0.7-0.80.30.5-0.70.70.5-0.7-0.51.20.31.10.70.30.20.7-0.2-0.4-0.4-1.3-1.21.0-0.1
Intraocular pressure2.33.37.11.8-1.42.62.1-1.7-2.0-1.71.5-2.62.61.9-0.8-1.82.61.72.72.11.51.42.1-1.4-1.9-1.3-0.8-0.11.0-0.2
Delta distance traveled before/after self-admin0.50.51.71.2-1.01.31.0-0.8-0.8-1.30.1-0.90.90.4-0.3-0.40.50.40.50.40.30.30.5-0.4-1.2-0.10.71.1-0.1-0.5
Delta ambulatory time before/after self-admin0.90.93.20.9-0.61.30.6-0.2-0.2-1.80.8-1.11.11.00.6-1.00.31.10.40.91.01.01.0-1.1-1.4-0.70.91.8-0.8-0.6
Parametrial fat weight0.10.21.40.3-0.30.0-0.00.30.2-0.7-0.3-0.0-0.0-0.10.30.1-0.5-0.1-0.4-0.2-0.1-0.0-0.2-0.1-0.10.10.91.2-0.5-1.0
Pavlov. Cond. lever latency0.70.82.71.4-1.21.41.2-1.0-0.9-1.60.1-1.11.10.4-0.3-0.40.60.40.60.40.30.30.6-0.5-1.5-0.11.01.4-0.2-1.3
Pavlov. Cond. magazine entry latency0.91.14.3-1.81.6-1.2-1.31.21.01.90.70.7-0.70.20.5-0.30.00.20.00.30.30.30.1-0.01.4-0.6-2.0-2.10.61.4
Pavlov. Cond. change in total contacts0.70.73.7-1.21.1-0.8-0.70.40.31.70.20.6-0.6-0.1-0.20.10.2-0.20.10.0-0.1-0.2-0.30.41.1-0.1-1.7-1.90.91.5
Pavlov. Cond. index score1.01.34.3-2.01.7-1.4-1.51.31.22.00.70.8-0.80.20.7-0.3-0.10.2-0.10.30.30.30.0-0.01.6-0.6-2.0-2.10.41.7
Pavlov. Cond. latency score1.11.44.9-2.01.7-1.6-1.51.31.12.20.41.1-1.1-0.10.50.0-0.3-0.1-0.3-0.00.0-0.0-0.30.31.8-0.3-1.9-2.20.61.7
Pavlov. Cond. lever contacts0.50.62.7-1.21.0-0.8-0.80.70.51.40.40.5-0.50.10.1-0.20.10.10.10.20.20.1-0.10.11.1-0.4-1.6-1.60.61.2
Pavlov. Cond. magazine entry number0.60.82.61.5-1.41.21.2-1.0-0.9-1.6-0.4-0.80.70.1-0.40.00.20.00.2-0.0-0.1-0.10.1-0.1-1.20.31.41.6-0.3-1.3
Pavlov. Cond. intertrial magazine entries0.20.31.0-0.10.3-0.4-0.30.20.30.3-0.70.7-0.7-0.5-0.00.6-0.7-0.5-0.8-0.7-0.5-0.6-1.00.60.50.60.60.3-0.40.1
Pavlov. Cond. lever-magazine prob. diff.1.01.34.7-1.91.7-1.1-1.41.21.01.81.00.5-0.50.50.7-0.60.20.50.20.60.60.50.3-0.31.4-0.9-2.2-2.10.51.6
Pavlov. Cond. response bias1.01.23.7-1.91.7-1.3-1.51.41.21.60.90.7-0.70.40.9-0.5-0.20.4-0.10.40.50.50.2-0.31.4-0.8-1.8-1.70.11.7
Pavlov. Cond. lever latency1.41.96.01.1-0.9-0.20.5-0.7-0.4-0.5-2.11.0-1.0-1.7-0.91.8-1.3-1.7-1.5-1.9-1.8-1.7-1.71.5-0.32.02.41.5-0.5-0.7
Pavlov. Cond. magazine entry latency1.31.53.5-0.60.70.6-0.40.60.5-0.31.8-1.11.11.71.1-1.90.91.81.11.81.91.81.5-1.6-0.2-1.8-1.4-0.3-0.30.2
Pavlov. Cond. change in total contacts2.33.27.3-2.62.7-1.1-2.42.52.40.92.40.1-0.01.72.6-1.9-0.32.00.01.62.12.11.3-1.81.1-2.3-1.8-0.9-1.21.5
Pavlov. Cond. index score2.12.76.0-1.61.5-0.0-1.21.51.20.32.5-0.80.92.11.8-2.30.82.21.02.12.32.31.7-2.00.5-2.4-2.1-0.9-0.50.9
Pavlov. Cond. latency score2.02.55.7-1.61.5-0.0-1.21.51.20.32.4-0.80.82.11.7-2.20.82.21.02.12.32.21.7-1.90.5-2.3-2.1-0.9-0.51.0
Pavlov. Cond. lever contacts1.62.16.1-1.51.2-0.1-0.91.10.80.62.2-0.80.81.81.2-1.91.01.81.21.91.91.91.7-1.60.5-2.1-2.5-1.50.21.0
Pavlov. Cond. magazine entry number1.11.43.31.1-1.1-0.00.9-1.1-1.0-0.0-1.70.6-0.6-1.5-1.41.7-0.4-1.7-0.7-1.6-1.8-1.7-1.21.5-0.31.81.30.40.6-0.5
Pavlov. Cond. intertrial magazine entries1.31.73.61.0-1.2-0.11.0-1.4-1.30.7-1.90.7-0.7-1.7-1.91.7-0.1-1.8-0.3-1.5-1.9-1.9-1.31.8-0.01.80.5-0.61.30.3
Pavlov. Cond. lever-magazine prob. diff.2.12.76.0-1.81.7-0.2-1.41.71.40.32.5-0.70.82.12.0-2.30.62.30.92.12.42.31.7-2.00.6-2.4-2.0-0.8-0.80.9
Pavlov. Cond. response bias1.31.84.3-1.31.2-0.0-0.91.10.90.42.0-0.70.71.71.2-1.80.81.71.01.71.81.81.4-1.50.5-1.9-2.1-1.1-0.10.7
Time in closed arm before self-admin0.91.02.8-1.41.7-1.5-1.41.11.21.5-0.31.4-1.4-0.90.50.8-1.1-0.7-1.1-0.9-0.6-0.6-1.00.71.20.5-0.0-0.9-0.4-0.0
Time in closed arm after self-admin0.90.92.1-1.10.9-1.4-1.00.70.71.5-0.71.3-1.3-1.00.01.0-0.9-1.0-1.0-1.0-0.9-0.8-1.10.91.20.6-0.3-1.00.10.0
Time in open arm before self-admin2.32.57.32.3-2.32.52.1-1.5-1.6-2.70.6-2.22.11.3-0.4-1.21.31.21.51.31.01.01.5-1.2-2.1-0.71.01.9-0.2-0.8
Time in open arm after self-admin0.80.92.6-1.21.2-0.8-1.31.61.50.01.00.2-0.20.71.6-0.8-0.70.8-0.50.51.01.00.5-0.90.5-1.0-0.00.4-1.20.9
Bone: periosteal estimation1.53.19.1-3.02.9-2.4-3.03.03.01.60.91.6-1.60.12.4-0.3-1.90.5-1.6-0.10.70.8-0.3-0.52.0-0.9-0.5-0.6-1.81.8
Bone: periosteal perimeter0.91.64.5-2.12.1-1.8-2.12.02.01.40.41.4-1.3-0.11.50.0-1.30.1-1.3-0.30.20.2-0.5-0.01.5-0.4-0.5-0.6-1.11.4
Bone: post-yield work0.20.31.20.5-0.60.50.7-0.8-0.90.2-0.1-0.40.3-0.0-0.90.10.8-0.20.70.1-0.2-0.30.10.3-0.30.2-0.6-0.71.1-0.5
Progressive ratio test 1 active lever presses1.61.64.4-0.20.31.0-0.10.90.3-0.92.0-1.31.32.11.1-1.90.91.81.01.81.81.81.7-1.7-0.4-1.6-0.70.4-0.20.2
Progressive ratio test 1 breakpoint1.41.53.9-0.20.30.9-0.00.70.1-0.61.9-1.21.22.00.8-1.81.11.71.21.81.71.61.7-1.5-0.3-1.5-1.1-0.10.30.1
Progressive ratio test 1 inactive lever presses3.53.87.31.7-1.52.71.6-0.5-1.1-2.72.0-2.72.72.60.3-2.31.82.42.12.42.22.22.5-2.2-2.0-1.70.41.4-0.1-0.2
Progressive ratio test 2 active lever presses1.11.13.3-0.50.70.4-0.41.10.6-0.61.8-0.80.81.71.2-1.40.51.60.61.51.61.51.4-1.4-0.2-1.3-0.50.4-0.20.1
Progressive ratio test 2 breakpoint1.31.54.1-0.30.50.8-0.10.80.3-0.72.0-1.21.21.91.0-1.70.91.81.11.81.81.71.8-1.6-0.4-1.5-0.80.20.20.1
Progressive ratio test 2 inactive lever presses1.41.74.40.0-0.10.80.00.90.3-1.41.9-1.31.42.11.2-1.70.61.90.91.71.91.91.8-1.8-0.4-1.6-0.00.7-0.71.0
Incentive Sensitization - Responses0.50.51.8-0.81.0-0.5-1.01.31.2-0.30.80.2-0.20.61.3-0.3-0.80.6-0.60.30.70.70.3-0.70.3-0.50.60.8-1.0-0.2
Incentive Sensitization - Breakpoint0.50.51.8-0.70.9-0.5-1.01.31.2-0.40.80.2-0.10.61.3-0.3-0.80.7-0.60.30.70.80.3-0.70.2-0.50.70.9-1.1-0.2
Sum of active levers in priming session hrs 5-60.70.72.0-0.90.8-1.2-1.10.91.20.4-0.51.1-1.1-0.70.80.7-1.4-0.5-1.4-0.8-0.5-0.4-0.80.40.70.30.40.8-0.70.1
Progressive ratio0.60.63.90.8-0.31.00.5-0.7-0.2-1.40.5-0.80.80.20.3-0.20.20.60.30.40.50.51.1-0.7-2.0-0.20.91.6-0.2-1.2
Food seeking constrained by brief footshock1.01.22.9-0.30.2-1.2-0.2-0.5-0.21.4-1.31.1-1.1-1.7-0.91.7-0.5-1.6-0.6-1.4-1.5-1.6-0.91.40.31.3-0.3-1.30.9-0.1
Seeking ratio, punishment vs. effort2.02.45.0-0.80.2-1.9-0.60.20.12.2-1.81.9-1.9-1.8-1.01.8-0.9-2.1-1.1-1.8-2.0-1.9-2.12.02.11.4-0.6-2.00.61.0
Retroperitoneal fat weight0.10.52.10.8-0.60.30.5-0.5-0.4-0.7-1.00.2-0.2-0.7-0.40.8-0.5-0.8-0.6-0.9-0.8-0.8-0.70.6-0.30.91.51.1-0.5-0.4
Reaction time number correct0.40.61.90.9-1.40.51.2-1.1-1.40.2-0.5-0.50.5-0.0-1.40.21.1-0.30.90.2-0.3-0.4-0.10.5-0.00.3-0.8-0.91.30.5
Reaction time mean minus median0.00.00.1-0.10.1-0.1-0.1-0.10.10.1-0.10.1-0.1-0.2-0.00.1-0.1-0.1-0.1-0.1-0.1-0.0-0.10.10.00.0-0.1-0.10.10.3
Reaction time mean minus median AUC0.20.31.2-0.20.00.20.1-0.0-0.20.30.5-0.40.40.5-0.1-0.60.70.60.70.70.50.50.5-0.40.3-0.6-1.1-0.90.60.2
Reaction time num false alarms0.91.24.01.8-1.61.61.5-1.3-1.1-2.0-0.0-1.31.30.4-0.4-0.40.60.60.70.50.50.40.7-0.6-1.9-0.11.31.8-0.3-0.1
Reaction time num false alarms AUC1.01.34.41.9-1.81.71.6-1.3-1.2-2.1-0.2-1.31.30.4-0.5-0.40.60.50.70.50.40.40.6-0.5-1.8-0.01.41.8-0.4-0.3
Reaction time trials correct on left0.40.61.90.9-1.40.51.2-1.1-1.40.2-0.5-0.50.5-0.0-1.40.21.1-0.30.90.2-0.3-0.4-0.10.5-0.00.3-0.8-0.91.30.5
Reaction time trials on left0.40.61.90.9-1.40.51.2-1.1-1.30.2-0.6-0.50.4-0.1-1.30.21.0-0.30.90.1-0.3-0.4-0.20.5-0.00.3-0.8-0.91.30.5
Reaction time mean1.31.86.1-1.92.4-1.4-2.32.12.50.20.71.1-1.1-0.12.3-0.2-1.90.4-1.7-0.30.50.70.0-0.60.5-0.51.01.1-1.9-0.6
Reaction time mean AUC1.11.55.0-1.72.1-1.1-2.01.92.20.00.80.8-0.80.12.2-0.3-1.60.5-1.4-0.10.60.80.1-0.80.4-0.60.91.1-1.8-0.6
Median of all reaction times2.23.010.1-2.43.1-1.7-2.92.73.20.21.11.3-1.20.03.1-0.4-2.30.7-2.0-0.20.81.00.2-1.00.5-0.81.21.4-2.5-0.7
Reaction time omissions0.20.20.7-0.30.2-0.5-0.50.60.7-0.1-0.30.5-0.5-0.30.60.3-0.9-0.0-0.8-0.3-0.0-0.0-0.40.00.40.10.60.7-0.6-0.5
Reaction time false alarm rate0.50.84.11.1-0.81.10.7-0.5-0.3-1.80.1-0.80.80.30.3-0.4-0.10.50.00.30.50.50.5-0.6-1.5-0.11.62.0-1.0-0.3
Reaction time premature initiation rate0.60.84.2-0.60.40.4-0.00.0-0.20.71.1-0.60.60.9-0.1-1.01.30.81.31.20.80.71.0-0.60.2-1.0-2.0-1.71.2-0.1
Reaction time premature initiations0.81.14.90.1-0.60.70.8-0.7-1.10.70.7-0.90.90.8-0.9-0.81.80.61.71.10.60.40.8-0.30.1-0.7-2.2-1.91.80.1
Std. dev. reaction times0.40.51.2-1.01.0-1.0-1.10.91.10.7-0.31.0-0.9-0.60.70.4-1.0-0.3-1.0-0.6-0.2-0.2-0.60.30.80.20.2-0.0-0.50.2
Reaction time trials completed0.40.61.90.9-1.40.51.2-1.1-1.30.2-0.6-0.50.4-0.1-1.30.21.0-0.30.90.1-0.3-0.4-0.20.5-0.00.3-0.8-0.91.30.5
Reaction time trials AUC0.30.41.60.8-1.30.41.0-0.9-1.20.1-0.5-0.40.40.0-1.10.10.9-0.20.80.2-0.2-0.3-0.10.40.00.2-0.7-0.71.10.4
Run reversals in cocaine runway, females0.10.10.40.3-0.40.30.3-0.0-0.2-0.50.1-0.40.40.40.0-0.40.20.40.30.40.40.40.1-0.30.0-0.30.30.1-0.40.6
Run reversals in cocaine runway, males1.01.02.7-0.91.10.0-0.60.70.60.31.5-0.50.51.30.9-1.40.61.50.71.51.61.60.9-1.10.4-1.3-1.0-0.9-0.20.3
Latency to leave start box in cocaine runway2.22.46.42.2-2.22.52.3-1.8-2.0-2.00.5-2.12.11.2-1.1-1.01.90.81.91.20.60.61.4-0.8-1.9-0.50.00.70.9-0.6
Latency to leave start box in cocaine runway, F1.11.22.71.4-1.61.51.4-1.0-1.1-1.60.5-1.61.61.1-0.4-1.01.21.01.31.10.90.91.2-0.9-1.1-0.70.10.60.20.4
Latency to leave start box in cocaine runway, M1.31.24.61.2-0.81.61.5-1.5-1.80.00.1-1.00.90.3-1.6-0.31.8-0.21.50.4-0.4-0.50.50.2-0.90.3-1.2-0.82.1-1.5
Std. dev. time between licks in bursts0.50.71.51.1-1.01.21.0-0.9-0.9-1.10.3-1.11.10.6-0.3-0.60.90.50.90.60.40.40.8-0.6-1.1-0.30.20.60.2-1.1
Total sessions with >9 infusions1.11.33.10.9-1.01.51.0-0.2-0.7-1.31.2-1.61.61.80.0-1.41.31.31.41.41.11.11.4-1.2-0.6-1.1-0.40.40.30.5
Short access day 1 total inactive lever presses0.00.00.10.2-0.40.10.20.2-0.1-0.2-0.1-0.10.10.1-0.00.2-0.1-0.1-0.0-0.1-0.00.0-0.10.00.10.10.30.2-0.2-0.1
Short access day 10 total inactive lever presses0.10.10.50.3-0.30.20.2-0.0-0.1-0.40.0-0.30.30.00.1-0.0-0.00.20.10.10.30.40.3-0.2-0.4-0.10.70.1-0.60.3
Short access day 1 total infusions0.60.61.50.6-0.81.10.8-0.2-0.7-0.70.8-1.11.11.2-0.2-0.91.10.81.11.00.70.70.9-0.7-0.3-0.7-0.8-0.10.70.2
Short access day 10 total infusions0.20.20.70.00.10.50.10.3-0.1-0.20.7-0.50.50.80.1-0.70.50.50.50.60.50.40.5-0.50.0-0.4-0.5-0.00.3-0.8
Short access total infusions0.70.72.00.7-0.61.20.7-0.1-0.5-1.01.0-1.21.21.40.1-1.01.01.01.01.10.90.91.1-0.9-0.6-0.8-0.40.50.30.3
Short access day 1 locomotion2.52.77.0-0.50.30.9-0.31.50.6-1.12.5-1.51.52.61.6-2.50.92.41.22.32.42.42.1-2.20.0-2.2-0.70.2-0.60.5
Short access day 10 total locomotion0.80.92.5-0.50.20.3-0.20.80.3-0.21.5-0.70.71.60.7-1.40.71.20.81.31.21.21.1-1.10.5-1.3-1.1-0.30.10.8
Short access total locomotion0.70.72.30.3-0.50.80.40.5-0.2-0.91.1-1.01.01.50.4-1.20.71.00.81.00.90.90.9-1.00.0-1.0-0.30.3-0.21.1
One hour access (0.3 mA shock)2.42.88.0-1.21.40.4-0.91.70.9-0.22.8-1.11.12.51.6-2.51.02.41.22.32.42.32.1-2.00.3-2.2-1.8-0.50.3-0.0
Compulsive drug intake0.90.92.4-0.91.0-0.1-0.71.20.80.11.5-0.40.41.41.1-1.50.41.30.51.21.21.20.9-1.10.7-1.3-1.0-0.5-0.10.5
One hour access (shock baseline)0.30.31.1-0.40.60.3-0.30.70.4-0.21.0-0.40.41.00.7-0.80.20.80.30.80.80.80.7-0.7-0.1-0.7-0.40.2-0.0-0.0
Social response proportion0.91.01.9-0.70.8-1.3-0.80.50.71.0-1.01.4-1.4-1.30.01.2-1.3-1.2-1.3-1.3-1.1-1.0-1.21.10.60.90.5-0.2-0.30.6
Social responses0.81.12.7-1.21.0-1.7-1.41.41.50.6-0.41.2-1.2-0.61.10.6-1.7-0.5-1.5-0.8-0.3-0.2-0.80.31.00.20.70.5-1.51.2
Social time0.20.30.9-0.91.0-0.8-0.90.80.90.50.10.6-0.6-0.30.70.2-0.7-0.2-0.6-0.3-0.10.0-0.1-0.00.4-0.10.1-0.2-0.40.2
Soleus weight0.30.92.30.9-1.1-0.10.7-0.8-0.80.1-1.50.5-0.5-1.1-1.21.3-0.3-1.3-0.5-1.2-1.4-1.4-1.21.30.21.40.80.20.7-0.4
Bone: stiffness1.52.45.8-2.12.0-2.4-2.32.02.21.6-0.62.1-2.1-1.21.31.0-2.2-0.8-2.2-1.3-0.6-0.6-1.30.71.60.50.7-0.2-1.41.5
Tibialis anterior weight0.00.10.40.3-0.40.40.20.0-0.1-0.60.2-0.50.50.40.2-0.40.10.40.30.30.40.40.4-0.4-0.2-0.30.20.5-0.3-0.6
Time to tail flick, vehicle, before self-admin0.20.20.70.00.20.4-0.10.30.3-0.60.6-0.40.40.60.6-0.60.00.60.10.50.70.60.5-0.6-0.5-0.50.30.9-0.5-0.4
Time to tail flick, vehicle, after self-admin0.00.00.40.3-0.10.30.1-0.1-0.1-0.40.0-0.20.20.10.1-0.1-0.00.1-0.00.00.10.10.1-0.1-0.30.00.60.3-0.4-0.1
Time to tail flick, test, before self-admin0.30.31.60.10.1-0.0-0.30.40.5-0.7-0.10.1-0.1-0.00.60.0-0.70.1-0.6-0.20.10.2-0.1-0.2-0.30.01.31.1-1.2-0.2
Time to tail flick, test, after self-admin1.11.13.41.5-1.41.51.7-1.7-1.9-0.4-0.3-1.01.00.1-1.60.01.5-0.21.30.3-0.3-0.40.30.3-1.10.4-0.6-0.21.6-0.9
Delta time to tail flick, vehicle, before/after SA0.50.51.51.0-1.00.51.0-1.1-1.1-0.0-0.8-0.20.2-0.6-1.20.60.5-0.70.4-0.4-0.7-0.7-0.40.7-0.30.70.2-0.60.60.2
Delta time to tail flick, test, before/after SA1.51.35.01.0-1.11.41.5-1.6-1.80.10.3-1.11.10.6-1.5-0.52.00.31.80.80.1-0.00.70.0-0.7-0.1-1.7-1.12.2-0.6
Tibia length2.15.914.7-3.63.5-3.7-3.83.53.72.5-0.13.0-3.0-1.12.50.9-3.2-0.7-3.0-1.4-0.4-0.3-1.60.62.90.20.1-0.5-2.12.9
Ambulatory time before self-admin1.81.93.8-0.50.3-1.6-0.70.20.41.4-1.81.7-1.7-1.9-0.51.9-1.4-1.9-1.5-1.9-1.8-1.7-1.91.71.11.60.6-0.3-0.10.2
Ambulatory time after self-admin0.20.21.10.2-0.1-0.1-0.10.00.2-0.3-0.40.3-0.3-0.40.20.4-0.6-0.4-0.6-0.5-0.3-0.3-0.40.2-0.20.40.81.0-0.5-0.6
Bone: tissue strength0.30.30.90.4-0.4-0.20.3-0.4-0.30.2-0.90.4-0.4-0.9-0.60.8-0.4-0.8-0.4-0.8-0.8-0.8-0.70.80.00.90.60.10.2-0.3
Total heroin consumption0.10.10.6-0.40.5-0.1-0.30.30.30.30.5-0.00.10.40.3-0.40.20.40.20.40.40.30.3-0.30.1-0.4-0.8-0.10.4-0.2
Bone: trabecular number2.43.77.5-0.50.1-1.8-0.4-0.3-0.22.4-2.52.3-2.3-2.6-1.62.6-1.2-2.7-1.5-2.4-2.6-2.7-2.62.71.72.40.1-1.81.40.8
Bone: trabecular spacing0.91.12.90.10.20.7-0.10.50.6-1.61.2-1.01.01.21.3-1.30.01.40.31.11.41.41.2-1.5-0.9-1.20.61.7-1.4-0.7
Bone: trabecular thickness0.80.92.50.0-0.3-0.60.3-0.7-0.71.3-1.10.7-0.8-1.2-1.31.20.1-1.3-0.1-0.9-1.3-1.3-0.91.40.61.1-0.6-1.61.30.5
Bone: trabecular tissue density2.12.96.7-1.41.40.1-1.41.81.7-0.72.6-1.01.02.12.5-2.30.12.40.62.02.42.52.1-2.4-0.0-2.5-0.80.5-1.5-0.3
Water consumed over 24 hours2.63.17.52.0-2.02.52.4-2.2-2.4-1.20.8-2.32.31.3-1.6-1.22.70.92.71.60.80.71.7-0.8-1.7-0.7-1.3-0.51.9-1.5
Number of responses in last shaping day0.70.71.9-0.40.20.3-0.10.70.2-0.21.3-0.70.81.40.6-1.40.71.20.81.21.11.11.1-1.00.3-1.2-0.9-0.50.30.4