Hub : Genes

Ankrd36

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression Ankrd36 0.32 0.12 0.0e+00 0.37 0.4 0.39 0.4 2.7e-43 2.0e-46 9.2e-46 1.3e-47
2 NAcc gene expression Ankrd36 0.21 0.11 0.0e+00 0.23 0.23 0.23 0.23 2.5e-26 4.1e-26 2.9e-26 2.5e-26
3 PL intron excision ratio chr14_80518014_80518684 0.03 0.02 1.6e-04 0.03 0.04 0.03 0.03 1.6e-04 7.8e-05 3.3e-04 1.9e-04
4 LHb gene expression Ankrd36 0.25 0.14 2.8e-04 0.06 0.13 0.13 0.14 1.3e-02 5.7e-04 5.2e-04 2.9e-04
5 IL gene expression Ankrd36 0.28 0.15 2.0e-05 0.14 0.18 0.16 0.17 2.5e-04 4.0e-05 1.5e-04 5.3e-05
6 Brain gene expression Ankrd36 0.43 0.16 0.0e+00 0.31 0.3 0.3 0.31 4.7e-29 2.3e-28 8.6e-29 5.5e-29
7 pVTA gene expression Ankrd36 0.13 0.08 2.5e-07 0.14 0.18 0.14 0.15 1.4e-06 4.4e-08 1.8e-06 6.2e-07
8 RMTg gene expression Ankrd36 0.1 0.08 5.0e-03 0.08 0.08 0.06 0.07 3.3e-03 3.0e-03 9.6e-03 5.6e-03
9 PL isoform ratio XR_005493388.1 0.02 0.01 3.9e-03 0.01 0.01 0 0 5.0e-02 1.4e-02 9.4e-02 1.0e-01
10 Adipose gene expression Ankrd36 0.02 0.02 2.9e-03 0.02 0.01 0 0.01 3.8e-03 1.8e-02 1.1e-01 2.6e-02
11 PL intron excision ratio chr14_80533133_80545526 0.02 0.02 4.9e-03 0.01 0.02 0.01 0.01 2.4e-02 2.7e-03 4.8e-02 1.2e-02
12 OFC gene expression Ankrd36 0.56 0.22 6.3e-06 0.1 0.22 0.19 0.15 2.2e-03 6.0e-06 2.6e-05 2.2e-04
13 BLA gene expression Ankrd36 0.23 0.11 3.8e-13 0.24 0.24 0.27 0.26 2.5e-13 5.1e-13 9.9e-15 5.9e-14

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density0.10.10.6-0.50.5-0.3-0.8-0.20.2-0.3-0.3-0.20.60.10.10.1
Area under the delay curve3.33.54.41.9-1.92.01.61.9-1.82.11.92.0-1.9-2.11.4-1.8
BMI with tail0.00.00.3-0.10.10.0-0.5-0.0-0.00.10.00.10.3-0.1-0.10.1
BMI without tail0.00.10.2-0.30.3-0.1-0.5-0.00.2-0.2-0.1-0.10.50.00.50.2
Body weight1.35.36.52.5-2.52.41.12.4-2.32.42.32.4-2.2-2.52.2-2.3
Weight adjusted by age0.50.61.60.8-0.80.8-0.10.9-0.70.60.70.7-0.6-0.81.3-0.9
Bone surface0.20.40.90.5-0.50.60.30.7-0.90.60.60.6-0.3-0.61.0-0.8
Bone volume0.20.40.90.4-0.40.60.10.7-0.90.60.60.6-0.3-0.71.0-0.8
Breakpoint value in progressive ratio session1.31.41.71.0-1.01.31.11.3-1.11.21.21.3-1.1-1.21.2-1.1
Number of licking bursts3.23.74.52.0-2.02.01.32.0-1.91.91.91.9-2.0-2.02.1-2.0
Context. condit. distance diff. score3.84.65.6-2.42.4-2.2-1.7-2.22.0-2.2-2.1-2.22.22.2-1.82.2
Locomotion velocity, session 10.20.21.10.4-0.40.01.0-0.1-0.20.10.1-0.1-0.40.3-0.70.0
Locomotion distance, session 10.81.02.5-1.21.2-0.9-1.6-0.91.0-0.7-1.0-0.80.90.5-1.20.5
Locomotion velocity, session 20.10.11.30.2-0.20.11.1-0.0-0.50.10.2-0.0-0.30.2-0.20.1
Locomotion distance, session 21.31.94.0-1.51.5-1.4-1.1-1.51.1-1.0-1.3-1.31.21.2-2.01.2
Locomotion velocity, session 32.42.83.9-2.02.0-1.7-1.9-1.71.4-1.6-1.7-1.61.81.5-1.41.4
Locomotion distance, session 30.20.20.9-0.10.10.4-0.10.4-0.90.60.40.5-0.2-0.60.4-0.4
Stereotopy head waving bouts, day 30.91.01.4-1.01.0-1.0-1.2-1.01.1-0.9-1.0-0.91.00.9-0.90.9
Stereotopy head waving duration, day 32.02.33.1-1.41.4-1.6-1.2-1.61.8-1.6-1.6-1.61.61.6-1.61.5
Locomotion velocity, session 70.20.20.40.4-0.30.50.30.4-0.70.50.50.5-0.4-0.50.5-0.5
Locomotion distance, session 70.20.30.5-0.60.6-0.5-0.4-0.60.1-0.4-0.4-0.50.50.5-0.70.5
Stereotopy head waving bouts, day 70.50.60.9-0.60.6-0.7-0.2-0.71.0-0.9-0.7-0.80.80.9-0.40.8
Stereotopy head waving duration, day 70.00.10.2-0.20.2-0.2-0.3-0.10.4-0.3-0.2-0.20.30.20.20.2
Locomotion velocity, session 81.21.41.9-1.31.2-1.2-0.5-1.30.9-1.2-1.1-1.31.01.4-1.31.3
Locomotion distance, session 87.611.213.2-3.63.6-3.5-2.6-3.53.1-3.3-3.3-3.43.33.4-3.43.3
Degree of sensitization distance2.12.13.1-1.21.1-1.5-0.6-1.61.6-1.6-1.5-1.61.21.8-1.61.5
Degree of sensitization stereotypy0.10.10.30.3-0.30.30.50.30.00.10.20.2-0.2-0.10.4-0.1
Conditioned locomotion1.31.53.7-1.41.4-1.2-1.9-1.21.1-0.9-1.3-1.01.30.8-1.30.9
Cocaine response after cond. corrected1.61.82.31.5-1.51.41.01.4-1.21.21.31.3-1.5-1.31.5-1.3
Cocaine response after cond. not corrected1.82.03.01.6-1.61.40.91.5-1.11.31.31.4-1.5-1.41.7-1.5
Cocaine response before conditioning0.30.40.6-0.70.6-0.7-0.6-0.60.8-0.7-0.7-0.60.80.6-0.50.5
Saline control response0.50.70.9-1.01.0-0.9-0.6-0.90.6-0.7-0.7-0.80.80.9-0.90.8
Bone: connectivity density0.20.30.7-0.70.7-0.5-0.8-0.50.4-0.6-0.5-0.50.80.4-0.20.3
Bone: cortical apparent density0.81.01.31.1-1.11.00.81.0-1.00.91.01.0-0.9-1.01.2-0.9
Bone: cortical area3.04.55.02.2-2.12.21.52.2-2.22.22.12.2-2.0-2.22.1-2.2
Bone: cortical porosity0.00.00.20.1-0.10.2-0.40.30.10.20.10.20.0-0.30.4-0.3
Bone: cortical porosity0.20.20.4-0.50.4-0.4-0.6-0.40.6-0.4-0.4-0.40.50.3-0.30.3
Bone: cortical thickness1.83.04.11.6-1.61.80.61.9-1.91.81.71.8-1.5-2.02.0-2.0
Bone: cortical thickness0.60.71.9-0.90.9-0.8-1.4-0.70.7-0.7-0.9-0.71.00.5-0.40.4
Bone: cortical tissue density0.81.11.41.2-1.21.10.91.1-1.01.01.01.0-0.9-1.01.2-0.9
Condit. Reinf. active minus inactive responses0.91.01.61.1-1.01.01.30.9-1.21.21.21.1-1.0-1.00.5-0.6
Condit. Reinf. active-inactive response ratio0.20.21.40.3-0.30.21.2-0.1-0.20.20.40.0-0.20.2-0.40.3
Condit. Reinf. active responses0.40.50.90.7-0.70.70.90.6-1.00.90.80.8-0.7-0.80.3-0.5
Condit. Reinf. inactive responses0.20.30.60.2-0.20.4-0.30.5-0.70.60.40.6-0.3-0.80.6-0.7
Incentive salience index mean1.21.52.31.2-1.11.31.01.1-1.41.51.41.3-1.1-1.40.7-0.9
Condit. Reinf. lever presses0.30.40.90.4-0.30.6-0.30.5-0.80.90.60.7-0.4-1.00.1-0.6
Condit. Reinf. active minus inactive responses0.40.61.0-0.70.7-0.8-0.6-0.80.8-0.7-0.7-0.70.60.7-1.00.8
Condit. Reinf. active-inactive response ratio0.00.00.4-0.10.1-0.1-0.3-0.20.10.1-0.1-0.0-0.0-0.0-0.60.2
Condit. Reinf. active responses0.60.81.7-0.80.8-0.9-0.7-1.01.0-0.8-0.9-0.90.70.9-1.30.9
Condit. Reinf. inactive responses0.80.91.3-0.80.8-1.0-0.6-1.01.1-1.1-1.0-1.10.81.2-1.10.9
Condit. Reinf. lever presses0.50.60.7-0.90.9-0.8-0.8-0.80.8-0.7-0.8-0.80.70.7-0.80.7
Condit. Reinf. lever reinforcers received0.50.71.5-0.80.8-0.9-0.8-0.90.9-0.7-0.8-0.80.60.8-1.20.8
Conditioned reinforcement - actives0.10.11.40.0-0.0-0.01.2-0.0-0.10.00.0-0.00.00.0-0.20.2
Conditioned reinforcement - inactives0.10.10.60.3-0.30.20.80.2-0.30.20.20.2-0.3-0.20.0-0.2
Conditioned locomotion0.10.11.4-0.00.00.11.20.1-0.10.10.10.20.1-0.20.10.4
Patch foraging indifference point 0 sec1.93.16.61.6-1.61.81.91.9-1.71.51.91.8-1.4-1.62.6-1.4
Patch foraging indifference point AUC0.20.20.70.4-0.40.40.80.4-0.40.30.40.4-0.4-0.30.4-0.4
Delay disc. indifference point, 0s delay0.90.91.21.0-1.01.00.31.1-0.90.90.91.0-1.0-1.01.1-1.1
Delay disc. indifference point, 16s delay2.72.84.01.7-1.61.82.01.6-1.61.91.71.7-1.7-1.71.0-1.4
Delay disc. indifference point, 2s delay1.01.11.90.9-0.91.1-0.11.2-0.81.21.01.2-0.9-1.41.2-1.2
Delay disc. indifference point, 24s delay1.61.52.11.3-1.31.21.31.1-1.11.51.31.3-1.3-1.30.6-1.1
Delay disc. indifference point, 4s delay2.83.04.21.7-1.71.80.61.8-1.61.91.71.9-1.7-2.01.6-1.7
Delay disc. indifference point, 8s delay1.11.11.61.1-1.11.11.01.0-1.11.31.01.1-1.1-1.20.4-1.0
Indifference point function ln k0.00.10.7-0.00.0-0.1-0.8-0.0-0.00.0-0.2-0.00.1-0.2-0.0-0.1
Indifference point function log k0.00.10.7-0.00.0-0.1-0.8-0.0-0.00.0-0.2-0.00.1-0.2-0.0-0.1
Patch foraging total patch changes 0 sec2.13.36.61.7-1.61.92.11.9-1.81.62.01.8-1.4-1.62.6-1.4
Patch foraging total patch changes 12 sec1.31.73.41.2-1.21.31.81.3-1.21.11.41.2-1.0-1.11.8-1.0
Patch foraging total patch changes 18 sec2.22.87.81.7-1.61.72.81.6-1.61.51.81.5-1.5-1.31.6-1.2
Patch foraging total patch changes 24 sec0.81.01.8-1.11.1-0.90.7-1.00.9-1.1-0.7-1.01.21.2-0.71.4
Patch foraging total patch changes 6 sec2.13.24.71.7-1.61.82.11.8-1.91.71.91.8-1.5-1.72.2-1.4
Patch foraging time to switch 0 sec0.50.71.0-0.70.7-0.9-0.6-0.91.0-0.8-0.9-0.90.80.8-1.00.8
Patch foraging water rate 0 sec1.93.03.61.6-1.61.81.71.8-1.91.71.91.8-1.6-1.71.9-1.4
Patch foraging water rate 12 sec0.10.10.20.1-0.10.3-0.10.3-0.50.30.30.3-0.2-0.40.4-0.3
Patch foraging water rate 18 sec0.10.21.1-0.30.3-0.3-1.1-0.20.5-0.1-0.4-0.10.4-0.1-0.10.0
Patch foraging water rate 24 sec0.10.10.40.3-0.30.20.70.1-0.30.30.20.2-0.2-0.2-0.30.0
Patch foraging water rate 6 sec0.30.40.70.5-0.50.60.20.7-0.60.70.60.7-0.8-0.80.5-0.7
Seeking ratio, delayed vs. immediate footshock0.40.51.5-0.50.5-0.6-0.4-0.70.9-0.4-0.6-0.50.60.4-1.20.8
Distance traveled before self-admin0.30.41.90.5-0.50.60.40.7-0.40.20.50.5-0.3-0.41.4-0.5
Distance traveled after self-admin0.20.20.60.4-0.40.50.20.5-0.30.40.40.5-0.3-0.60.8-0.5
Extensor digitorum longus weight3.313.215.73.8-3.73.72.83.8-3.63.63.73.7-3.6-3.74.0-3.4
Bone: elastic displacement0.70.71.2-1.01.0-0.9-0.9-0.70.9-1.0-0.9-0.91.10.8-0.30.6
Bone: elastic work0.10.10.4-0.00.00.1-0.70.20.00.10.00.20.2-0.30.6-0.3
Bone: endosteal estimation0.10.20.70.6-0.60.40.80.4-0.30.30.40.4-0.4-0.30.5-0.2
Bone: endosteal perimeter0.61.31.81.3-1.31.11.41.1-0.91.21.01.1-1.2-1.10.6-1.0
Epididymis fat weight0.30.71.7-0.80.8-0.9-1.3-0.80.9-1.0-1.0-0.90.90.8-0.20.4
Delta time in closed arm before/after self-admin6.96.67.2-2.72.6-2.6-2.4-2.62.7-2.6-2.7-2.62.62.5-2.62.2
Delta time in open arm before/after self-admin8.58.210.23.2-3.23.02.42.9-2.92.83.02.9-2.7-2.72.9-2.5
Diff in mean of infusions in LGA sessions0.30.30.6-0.60.6-0.5-0.3-0.50.7-0.5-0.5-0.50.70.4-0.50.5
Delay discount exponential model param3.03.24.0-1.81.8-1.9-1.5-1.81.7-2.0-1.8-1.91.82.0-1.41.7
Extinction: sum of active levers before priming0.60.62.10.7-0.70.71.50.6-0.70.90.70.7-0.6-0.70.2-0.5
Active lever presses in extinction session 60.10.10.20.3-0.30.3-0.10.4-0.10.30.20.3-0.1-0.40.5-0.5
Bone: final force0.40.71.00.8-0.80.80.70.8-1.00.80.80.8-0.7-0.81.0-0.7
Bone: final moment0.61.01.51.0-1.01.00.81.0-1.10.91.01.0-0.8-1.01.2-0.8
Food consumed during 24 hour testing period2.12.53.31.6-1.61.61.81.6-1.71.61.71.6-1.7-1.41.4-1.4
Glucose18.327.646.95.7-5.75.36.94.9-5.75.15.54.9-5.6-4.34.0-4.0
Heart weight0.30.40.7-0.40.4-0.70.3-0.70.3-0.6-0.5-0.70.70.8-0.70.7
Delay discount hyperbolic model param3.13.24.3-1.81.8-1.9-1.3-1.91.7-2.0-1.8-2.01.82.1-1.41.7
Intermittent access intake day 1-15 change0.50.53.60.4-0.30.51.90.4-0.80.50.70.5-0.6-0.40.4-0.3
Intermittent access intake escalation0.30.32.60.3-0.30.31.60.3-0.60.30.50.3-0.3-0.20.3-0.2
Intermittent access intake escalation 20.20.21.50.3-0.30.31.20.3-0.50.20.40.2-0.3-0.10.5-0.2
Intermitt. access day 1 inactive lever presses0.80.93.1-0.60.6-1.0-1.1-1.10.9-0.6-1.0-0.90.60.7-1.80.8
Intermitt. access day 15 inactive lever presses1.01.11.71.3-1.31.00.90.8-1.11.31.11.0-1.3-1.00.2-0.9
Intermitt. access escalation Index0.20.20.60.4-0.30.30.70.3-0.50.30.50.3-0.3-0.20.3-0.3
Intermittent access day 1 total infusions0.10.20.4-0.40.4-0.30.1-0.30.7-0.5-0.4-0.40.50.4-0.20.4
Intermittent access day 15 total infusions0.30.32.20.3-0.30.41.50.4-0.40.30.40.4-0.3-0.30.5-0.2
Intermittent access terminal intake (last 3 days)0.30.32.60.2-0.20.31.60.3-0.30.10.40.2-0.2-0.10.6-0.2
Intermittent access total infusions0.10.11.10.0-0.00.21.00.2-0.00.10.20.2-0.0-0.10.4-0.0
Intermittent access day 1 locomotion1.01.01.6-1.01.0-1.0-0.2-1.01.1-0.9-1.1-1.01.10.9-1.31.2
Intermittent access day 15 total locomotion0.20.31.40.4-0.40.51.20.4-0.40.60.40.5-0.3-0.5-0.1-0.1
Intermittent access total locomotion0.20.31.50.3-0.30.51.20.4-0.40.60.40.5-0.3-0.50.0-0.2
Intermittent access standard deviation1.21.21.9-1.21.1-1.2-0.0-1.11.1-1.4-1.1-1.21.11.3-0.61.2
Left kidney weight0.00.10.30.2-0.2-0.4-0.5-0.30.6-0.2-0.4-0.30.10.1-0.4-0.0
Right kidney weight0.82.23.3-1.31.3-1.6-1.8-1.51.8-1.6-1.7-1.51.51.3-1.21.1
Cocaine induced anxiety3.03.54.91.8-1.71.91.41.9-2.22.01.91.9-1.9-2.01.7-1.7
Post-drug Anxiety1.01.21.71.2-1.11.01.11.0-1.31.11.11.0-1.2-1.00.8-0.8
Baseline Anxiety0.30.31.0-0.20.2-0.5-0.0-0.60.7-0.4-0.5-0.50.30.6-1.00.6
Tail length1.34.07.61.9-1.92.01.22.2-1.81.91.92.1-1.8-2.22.8-2.0
Length with tail2.07.38.83.0-2.92.81.92.8-2.52.82.62.8-2.7-2.92.7-2.7
Length without tail1.22.73.61.9-1.91.71.41.6-1.61.81.61.7-1.8-1.70.9-1.6
Times rat made contact with spout0.20.32.00.4-0.40.21.40.2-0.6-0.10.4-0.0-0.50.40.4-0.0
Lifetime Intake0.10.10.90.1-0.10.30.90.3-0.00.10.20.2-0.1-0.20.6-0.1
Liver weight, left1.93.15.2-1.51.4-1.8-2.0-1.72.3-1.9-2.0-1.81.91.6-1.31.3
Liver weight, right3.86.38.2-2.42.3-2.6-2.9-2.52.8-2.4-2.8-2.52.52.2-2.71.8
Locomotor activity0.71.13.41.2-1.11.11.91.0-0.60.81.10.9-1.2-0.61.1-0.6
Locomotor testing distance0.20.31.20.5-0.50.50.10.6-0.00.30.50.5-0.7-0.51.1-0.5
Locomotor testing rearing2.03.04.11.7-1.61.81.91.8-1.61.61.81.7-1.9-1.62.0-1.5
Locomotion in novel chamber4.85.96.9-2.62.5-2.5-2.5-2.42.2-2.6-2.5-2.52.42.5-2.02.1
Locomotion in novel chamber post-restriction3.23.87.7-1.91.8-2.0-1.6-2.21.6-1.8-2.0-2.01.72.0-2.81.7
Fecal boli incidents, locomotor time 10.30.31.3-0.30.3-0.5-1.1-0.50.5-0.4-0.5-0.50.30.4-0.70.4
Change in fecal boli incidents, locomotor task0.20.21.40.3-0.30.21.20.1-0.30.20.30.2-0.4-0.00.10.2
Time >=10cm from walls, locomotor time 10.10.10.20.1-0.1-0.20.1-0.20.1-0.4-0.3-0.3-0.10.4-0.2-0.1
Bouts of movement, locomotor time 10.50.61.60.9-0.80.81.30.7-0.90.60.90.6-0.8-0.40.6-0.3
Total resting periods, locomotor time 10.20.21.00.5-0.50.41.00.3-0.50.40.50.3-0.5-0.10.00.1
Rest time, locomotor task time 10.00.10.10.3-0.30.10.30.1-0.40.10.10.0-0.40.1-0.2-0.1
Distance moved, locomotor task time 10.20.30.60.4-0.30.50.80.5-0.30.50.40.6-0.3-0.70.7-0.5
Vertical activity count, locomotor time 10.10.10.60.1-0.10.30.80.3-0.10.20.30.3-0.1-0.30.5-0.3
Time >=10cm from walls, locomotor time 20.30.31.0-0.40.3-0.5-0.3-0.60.8-0.6-0.7-0.60.40.7-1.00.3
Bouts of movement, locomotor time 20.10.10.5-0.10.2-0.0-0.3-0.10.20.40.00.20.2-0.5-0.70.2
Total resting periods, locomotor time 20.10.10.3-0.00.00.1-0.1-0.00.10.50.10.30.1-0.5-0.60.2
Rest time, locomotor task time 20.00.00.1-0.10.1-0.20.0-0.10.1-0.2-0.1-0.20.00.30.00.2
Distance moved, locomotor task time 20.10.10.2-0.20.2-0.30.2-0.30.2-0.3-0.3-0.30.20.3-0.50.1
Vertical activity count, locomotor time 20.10.10.1-0.30.2-0.2-0.1-0.20.1-0.4-0.4-0.30.30.4-0.2-0.1
Light reinforcement 10.10.20.40.3-0.30.30.20.4-0.40.40.30.4-0.3-0.50.6-0.4
Light reinforcement 20.10.10.40.2-0.20.2-0.60.2-0.00.30.00.2-0.2-0.4-0.1-0.4
Bone: marrow area0.10.10.60.5-0.50.30.80.3-0.20.20.30.2-0.3-0.20.3-0.1
Bone: maximum diameter4.99.010.23.2-3.13.12.93.0-3.03.13.13.0-3.1-2.92.6-2.7
Bone: maximum force0.30.50.90.7-0.70.70.50.8-0.80.70.70.7-0.6-0.81.0-0.7
Bone: maximum moment0.50.81.50.9-0.90.90.61.0-0.90.80.90.9-0.7-1.01.2-0.9
Mean time between licks in bursts0.60.82.81.0-1.00.81.70.6-1.00.80.90.7-1.2-0.50.2-0.5
Mean num. licks in bursts2.02.33.6-1.51.5-1.6-0.2-1.71.2-1.6-1.4-1.71.41.9-1.61.8
Cd content in liver0.30.30.6-0.60.6-0.5-0.7-0.50.8-0.5-0.6-0.50.60.4-0.40.5
Co content in liver0.00.00.2-0.20.30.1-0.10.1-0.10.10.20.20.1-0.20.40.2
Cu content in liver0.50.60.80.8-0.80.80.70.7-0.80.70.80.7-0.9-0.70.7-0.7
Fe content in liver0.40.42.5-0.50.5-0.60.3-0.80.2-0.3-0.5-0.60.40.7-1.60.7
K content in liver0.50.51.30.4-0.40.7-0.50.8-0.60.70.50.8-0.6-1.00.9-1.1
Mg content in liver0.30.30.60.3-0.20.60.00.7-0.70.60.60.6-0.5-0.70.8-0.8
Mn content in liver0.20.20.7-0.20.20.2-0.80.4-0.30.30.10.40.1-0.60.6-0.6
Na content in liver4.04.24.92.0-2.02.11.92.1-2.22.22.12.1-2.2-2.01.7-1.9
Rb content in liver2.83.44.91.7-1.71.91.22.1-1.71.91.92.0-1.8-2.02.2-1.9
Se content in liver1.51.82.61.2-1.11.40.41.5-1.41.51.41.5-1.2-1.61.5-1.5
Sr content in liver1.81.62.21.5-1.51.31.01.2-1.31.41.31.3-1.5-1.30.7-1.0
Zn content in liver0.30.30.50.3-0.30.5-0.20.5-0.60.70.50.6-0.6-0.70.3-0.7
Bone: minimum diameter0.00.00.0-0.10.0-0.0-0.10.00.2-0.0-0.1-0.00.2-0.10.0-0.2
Time in familiar zone, hab. session 10.10.10.3-0.50.5-0.3-0.4-0.30.0-0.3-0.3-0.30.50.3-0.20.3
Time in novel zone, hab. session 10.40.41.10.7-0.70.60.30.7-0.30.40.60.6-0.7-0.51.0-0.7
Total zone transitions, hab. session 10.00.00.10.1-0.10.1-0.00.1-0.30.20.10.1-0.2-0.1-0.1-0.1
Total locomotion distance, hab. session 10.10.10.30.2-0.20.3-0.30.3-0.50.40.20.4-0.3-0.50.1-0.5
Locomotion velocity, hab. session 10.00.00.1-0.00.00.0-0.10.0-0.20.2-0.00.1-0.1-0.1-0.3-0.2
Time in familiar zone, hab. session 21.81.82.3-1.31.3-1.4-0.7-1.51.5-1.4-1.3-1.41.31.4-1.51.4
Time in novel zone, hab. session 22.72.74.31.5-1.51.71.11.8-1.81.51.71.6-1.6-1.62.1-1.7
Total zone transitions, hab. session 20.70.91.50.9-0.91.00.30.9-1.11.20.91.1-1.1-1.20.4-1.0
Total locomotion distance, hab. session 20.91.22.00.9-0.91.10.81.0-1.41.41.11.2-1.2-1.30.4-1.1
Locomotion velocity, hab. session 21.11.52.51.1-1.11.20.81.2-1.41.61.21.3-1.3-1.50.4-1.2
Novel to familiar place preference ratio0.90.91.81.3-1.40.91.30.9-0.90.70.90.7-1.1-0.60.6-0.7
Novelty place preference1.01.01.91.4-1.40.91.30.9-0.90.70.90.8-1.2-0.60.7-0.8
Time in novel zone, NPP test0.91.01.81.3-1.40.91.30.9-1.00.70.90.8-1.1-0.60.8-0.8
Total zone transitions, NPP test0.50.71.9-1.11.1-0.8-1.4-0.70.6-0.5-0.8-0.60.80.4-0.90.4
Total locomotion distance, NPP test0.10.20.7-0.60.6-0.3-0.8-0.40.10.0-0.4-0.20.3-0.1-0.80.0
Locomotion velocity, NPP test0.10.10.5-0.40.4-0.1-0.5-0.1-0.10.3-0.20.00.1-0.3-0.7-0.2
Intraocular pressure0.40.50.80.9-0.80.70.90.6-0.70.80.70.7-0.8-0.60.2-0.5
Delta distance traveled before/after self-admin0.30.31.3-0.40.4-0.6-0.6-0.60.6-0.3-0.6-0.50.40.3-1.10.4
Delta ambulatory time before/after self-admin0.50.61.7-0.60.6-0.8-0.8-0.90.7-0.5-0.8-0.70.60.5-1.30.6
Parametrial fat weight2.03.97.22.3-2.32.02.71.7-1.92.12.01.9-2.1-1.80.8-1.4
Pavlov. Cond. lever latency0.60.71.71.1-1.10.81.30.8-0.70.70.90.7-1.0-0.50.8-0.6
Pavlov. Cond. magazine entry latency2.22.84.1-2.02.0-1.7-1.8-1.71.5-1.6-1.6-1.61.91.5-1.51.4
Pavlov. Cond. change in total contacts1.01.01.80.8-0.71.10.51.0-1.31.21.11.2-0.8-1.20.9-0.9
Pavlov. Cond. index score2.43.14.5-2.12.1-1.7-2.1-1.71.5-1.5-1.7-1.61.91.4-1.71.5
Pavlov. Cond. latency score2.02.53.7-1.91.9-1.6-1.9-1.51.3-1.4-1.5-1.41.71.3-1.51.3
Pavlov. Cond. lever contacts1.01.22.3-1.41.4-1.0-1.5-1.00.8-0.7-1.0-0.91.20.7-1.10.9
Pavlov. Cond. magazine entry number2.42.94.42.1-2.11.71.71.7-1.31.61.61.6-2.0-1.51.5-1.5
Pavlov. Cond. intertrial magazine entries0.30.40.70.7-0.80.60.10.6-0.40.70.40.7-0.6-0.80.4-0.8
Pavlov. Cond. lever-magazine prob. diff.2.83.55.1-2.32.3-1.9-2.3-1.81.6-1.6-1.8-1.72.01.5-1.81.6
Pavlov. Cond. response bias1.31.53.0-1.61.7-1.2-1.7-1.10.8-0.9-1.1-1.01.60.8-1.01.0
Pavlov. Cond. lever latency3.64.86.12.2-2.22.31.12.3-2.12.32.12.3-2.2-2.52.3-2.3
Pavlov. Cond. magazine entry latency0.00.00.1-0.30.3-0.1-0.1-0.0-0.1-0.1-0.1-0.10.10.10.1-0.1
Pavlov. Cond. change in total contacts0.20.30.5-0.50.5-0.6-0.2-0.60.6-0.6-0.5-0.60.50.7-0.70.6
Pavlov. Cond. index score1.31.72.0-1.41.4-1.3-0.8-1.41.2-1.3-1.3-1.41.31.4-1.31.2
Pavlov. Cond. latency score1.41.82.1-1.51.4-1.4-1.0-1.41.2-1.3-1.3-1.41.41.4-1.31.2
Pavlov. Cond. lever contacts3.04.15.4-2.01.9-2.1-0.9-2.22.1-2.1-2.0-2.21.92.3-2.22.2
Pavlov. Cond. magazine entry number0.00.00.20.2-0.20.1-0.50.10.10.2-0.00.1-0.1-0.3-0.2-0.2
Pavlov. Cond. intertrial magazine entries0.00.00.10.0-0.00.0-0.0-0.00.00.20.10.1-0.2-0.1-0.20.1
Pavlov. Cond. lever-magazine prob. diff.1.31.61.9-1.41.4-1.3-0.8-1.31.2-1.3-1.3-1.31.31.4-1.21.2
Pavlov. Cond. response bias1.21.62.4-1.21.2-1.3-0.2-1.41.3-1.4-1.2-1.41.21.6-1.31.4
Time in closed arm before self-admin0.50.61.70.7-0.70.80.50.9-0.60.60.70.7-0.6-0.71.3-0.8
Time in closed arm after self-admin2.12.12.7-1.71.6-1.5-1.2-1.41.6-1.5-1.5-1.41.51.4-1.21.3
Time in open arm before self-admin2.72.93.8-1.71.7-1.8-1.2-1.81.7-1.7-1.8-1.81.71.7-1.91.6
Time in open arm after self-admin0.20.20.50.6-0.60.40.70.3-0.40.50.50.4-0.3-0.3-0.1-0.0
Bone: periosteal estimation1.02.12.51.6-1.61.51.41.5-1.41.41.41.4-1.4-1.41.5-1.4
Bone: periosteal perimeter1.83.13.71.9-1.91.81.71.7-1.71.81.71.8-1.8-1.81.3-1.7
Bone: post-yield work0.20.30.40.7-0.70.50.60.6-0.50.50.50.5-0.6-0.50.6-0.6
Progressive ratio test 1 active lever presses0.00.00.50.1-0.10.10.70.00.10.10.00.00.0-0.0-0.10.0
Progressive ratio test 1 breakpoint0.10.10.2-0.30.3-0.30.4-0.40.5-0.3-0.3-0.40.40.4-0.50.3
Progressive ratio test 1 inactive lever presses2.22.43.51.8-1.71.60.71.5-1.41.91.51.7-1.7-1.80.8-1.6
Progressive ratio test 2 active lever presses0.10.11.30.1-0.10.21.20.2-0.1-0.00.10.1-0.0-0.00.3-0.2
Progressive ratio test 2 breakpoint0.10.21.70.0-0.00.21.30.2-0.10.00.20.1-0.1-0.00.3-0.2
Progressive ratio test 2 inactive lever presses0.70.83.10.9-0.90.81.80.7-0.81.00.80.8-0.9-0.80.1-0.6
Incentive Sensitization - Responses0.10.11.50.1-0.10.21.20.1-0.20.00.20.1-0.30.00.2-0.1
Incentive Sensitization - Breakpoint0.10.11.30.0-0.00.11.10.1-0.1-0.10.1-0.0-0.20.10.2-0.0
Sum of active levers in priming session hrs 5-61.00.91.41.2-1.10.90.00.9-1.01.10.91.0-1.0-1.10.6-1.1
Progressive ratio0.10.20.3-0.40.4-0.3-0.4-0.30.6-0.4-0.4-0.30.60.3-0.20.5
Food seeking constrained by brief footshock1.92.33.41.5-1.51.50.61.6-1.51.61.31.6-1.3-1.91.6-1.9
Seeking ratio, punishment vs. effort1.21.42.51.2-1.21.10.41.2-1.31.31.11.2-1.3-1.31.0-1.6
Retroperitoneal fat weight0.00.10.80.1-0.1-0.10.0-0.30.20.2-0.1-0.00.1-0.1-0.90.1
Reaction time number correct0.10.10.80.1-0.10.20.90.2-0.20.20.30.2-0.4-0.10.20.0
Reaction time mean minus median1.41.93.1-1.21.1-1.4-0.4-1.51.5-1.5-1.3-1.51.21.8-1.41.4
Reaction time mean minus median AUC1.11.52.4-1.11.1-1.3-0.5-1.21.4-1.5-1.2-1.41.11.6-0.91.1
Reaction time num false alarms0.20.30.8-0.00.10.5-0.30.6-0.80.70.50.7-0.1-0.90.7-0.6
Reaction time num false alarms AUC0.20.30.7-0.20.20.4-0.50.5-0.60.60.40.60.0-0.80.6-0.5
Reaction time trials correct on left0.10.10.80.1-0.10.20.90.2-0.20.20.30.2-0.4-0.10.20.0
Reaction time trials on left0.10.10.80.0-0.00.20.90.2-0.10.20.30.2-0.3-0.10.20.1
Reaction time mean0.81.11.9-0.80.8-1.1-0.7-1.21.2-1.0-1.0-1.10.81.1-1.41.1
Reaction time mean AUC1.31.72.4-1.11.0-1.4-1.0-1.41.5-1.3-1.3-1.41.11.4-1.61.3
Median of all reaction times0.40.61.4-0.50.5-0.8-0.5-0.90.9-0.6-0.7-0.70.50.7-1.20.8
Reaction time omissions1.31.82.6-1.31.3-1.4-1.0-1.41.6-1.3-1.3-1.31.51.3-1.31.3
Reaction time false alarm rate0.20.31.0-0.10.20.3-1.00.4-0.50.50.20.50.1-0.80.6-0.5
Reaction time premature initiation rate2.93.96.5-2.02.0-2.0-2.5-1.92.0-2.0-2.1-2.02.01.8-1.71.5
Reaction time premature initiations1.42.02.7-1.51.5-1.5-1.6-1.41.5-1.5-1.5-1.41.41.3-1.11.1
Std. dev. reaction times1.31.82.6-1.11.1-1.4-0.5-1.51.5-1.4-1.3-1.41.11.6-1.61.4
Reaction time trials completed0.10.10.80.0-0.00.20.90.2-0.10.20.30.2-0.3-0.10.20.1
Reaction time trials AUC0.10.10.90.2-0.10.30.90.3-0.20.30.40.3-0.4-0.20.3-0.1
Run reversals in cocaine runway, females0.70.71.2-0.90.9-0.8-0.7-0.90.6-0.6-0.8-0.70.90.6-1.10.8
Run reversals in cocaine runway, males0.50.50.80.7-0.70.70.80.7-0.60.50.60.6-0.7-0.60.9-0.6
Latency to leave start box in cocaine runway0.10.10.3-0.10.20.2-0.60.2-0.00.30.20.30.2-0.40.3-0.0
Latency to leave start box in cocaine runway, F0.50.51.00.6-0.60.7-0.60.8-0.80.70.70.8-0.6-0.91.0-0.6
Latency to leave start box in cocaine runway, M0.80.81.4-1.11.2-0.8-0.2-0.91.1-0.8-0.7-0.81.20.8-0.90.9
Std. dev. time between licks in bursts0.00.00.2-0.00.10.00.4-0.0-0.20.10.10.0-0.10.0-0.00.0
Total sessions with >9 infusions0.00.00.2-0.30.3-0.10.30.00.1-0.3-0.1-0.10.20.10.50.1
Short access day 1 total inactive lever presses3.23.54.41.8-1.82.01.42.0-1.81.91.92.0-1.6-2.12.0-1.9
Short access day 10 total inactive lever presses0.30.31.1-0.50.5-0.5-1.0-0.60.3-0.3-0.5-0.40.40.3-0.80.4
Short access day 1 total infusions0.20.30.6-0.50.5-0.50.0-0.40.8-0.7-0.6-0.50.50.5-0.20.4
Short access day 10 total infusions0.30.30.6-0.60.6-0.5-0.3-0.40.8-0.7-0.6-0.50.70.5-0.10.4
Short access total infusions0.30.30.7-0.70.7-0.5-0.2-0.40.8-0.8-0.6-0.60.70.60.20.5
Short access day 1 locomotion1.51.62.0-1.41.4-1.3-1.2-1.21.4-1.4-1.4-1.31.41.1-0.71.2
Short access day 10 total locomotion0.60.71.1-0.80.8-0.8-0.3-0.81.0-0.7-0.9-0.80.90.6-1.01.0
Short access total locomotion3.33.54.3-2.01.9-1.9-1.3-1.82.1-2.0-2.0-1.92.01.8-1.42.0
One hour access (0.3 mA shock)0.10.10.8-0.20.20.00.90.00.1-0.1-0.0-0.10.30.10.10.2
Compulsive drug intake2.42.43.0-1.51.5-1.6-1.7-1.61.4-1.6-1.6-1.61.51.6-1.41.5
One hour access (shock baseline)0.70.93.50.7-0.61.01.90.9-0.70.80.90.9-0.6-0.80.8-0.7
Social response proportion1.82.02.91.7-1.71.41.01.2-1.61.71.41.4-1.7-1.40.2-1.3
Social responses2.32.93.91.8-1.81.81.81.6-1.82.01.81.8-1.8-1.70.9-1.3
Social time0.20.30.60.6-0.60.50.60.4-0.50.80.60.6-0.7-0.6-0.2-0.3
Soleus weight0.72.12.91.7-1.71.40.61.5-1.11.41.31.5-1.5-1.61.5-1.6
Bone: stiffness0.00.00.20.2-0.2-0.10.4-0.10.1-0.1-0.1-0.1-0.10.1-0.00.0
Tibialis anterior weight1.24.25.22.3-2.22.12.02.1-1.92.02.12.0-2.0-2.02.1-1.8
Time to tail flick, vehicle, before self-admin0.10.10.4-0.30.3-0.2-0.5-0.20.20.1-0.2-0.10.3-0.1-0.60.2
Time to tail flick, vehicle, after self-admin0.00.00.4-0.10.1-0.0-0.6-0.00.10.2-0.00.10.1-0.3-0.20.0
Time to tail flick, test, before self-admin0.60.51.2-0.60.5-0.8-0.4-0.70.8-1.1-0.8-0.90.71.0-0.10.6
Time to tail flick, test, after self-admin2.93.04.21.7-1.61.80.51.8-1.71.91.71.9-1.7-2.11.6-1.8
Delta time to tail flick, vehicle, before/after SA0.00.00.10.1-0.10.0-0.30.00.1-0.0-0.0-0.0-0.00.00.0-0.0
Delta time to tail flick, test, before/after SA2.11.93.11.2-1.21.40.91.4-1.51.81.41.5-1.4-1.70.8-1.3
Tibia length0.10.20.8-0.30.2-0.4-0.9-0.30.5-0.4-0.5-0.30.40.1-0.10.1
Ambulatory time before self-admin0.70.73.00.7-0.70.80.41.0-0.60.50.80.8-0.6-0.81.7-0.8
Ambulatory time after self-admin0.30.30.50.5-0.50.50.20.6-0.40.50.50.6-0.4-0.70.7-0.6
Bone: tissue strength0.20.21.00.4-0.40.21.00.2-0.0-0.10.20.0-0.30.20.60.0
Total heroin consumption0.10.10.4-0.10.10.30.70.30.00.30.30.3-0.1-0.30.4-0.0
Bone: trabecular number0.10.10.3-0.30.3-0.2-0.5-0.10.3-0.3-0.2-0.20.50.10.40.1
Bone: trabecular spacing1.11.42.21.3-1.31.21.11.1-1.31.21.21.1-1.5-1.10.9-1.1
Bone: trabecular thickness1.21.52.4-1.41.4-1.2-1.4-1.21.2-1.1-1.2-1.11.60.9-1.10.9
Bone: trabecular tissue density0.20.30.8-0.30.3-0.50.6-0.60.4-0.5-0.5-0.60.30.8-0.90.7
Water consumed over 24 hours1.51.83.01.4-1.41.31.71.3-1.61.21.41.2-1.4-1.11.2-1.1
Number of responses in last shaping day0.00.00.2-0.40.4-0.1-0.3-0.1-0.0-0.1-0.2-0.10.3-0.00.00.1