Hub : Genes

Ankrd36

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc alternative polyA NM_001419749.1 0.03 0.03 5.5e-03 0.01 0.01 0 0.01 8.3e-03 3.7e-02 1.0e-01 1.9e-02
2 PL intron excision ratio chr14_84731993_84732661 0.03 0.02 2.4e-04 0.03 0.03 0.02 0.03 3.3e-04 4.8e-04 4.4e-03 8.3e-04
3 PL gene expression Ankrd36 0.36 0.13 0.0e+00 0.39 0.41 0.41 0.42 1.3e-45 1.7e-48 1.1e-47 2.4e-49
4 IC isoform ratio NM_001419750.1 0.06 0.06 4.8e-03 0.04 0.05 0.04 0.04 1.0e-02 5.0e-03 1.1e-02 9.5e-03
5 Brain gene expression Ankrd36 0.44 0.16 0.0e+00 0.33 0.33 0.33 0.33 7.2e-32 9.1e-32 1.2e-31 7.4e-32
6 PL alternative polyA XM_008770392.4 0.02 0.02 9.2e-03 0.01 0.01 0.01 0 1.3e-02 4.6e-02 3.1e-02 1.1e-01
7 Adipose gene expression Ankrd36 0.05 0.03 5.2e-06 0.04 0.03 0.04 0.04 3.0e-05 9.7e-05 7.6e-05 7.5e-05
8 pVTA gene expression Ankrd36 0.14 0.07 0.0e+00 0.24 0.25 0.25 0.25 3.0e-19 4.7e-20 2.9e-20 6.9e-20
9 IL gene expression Ankrd36 0.33 0.16 1.8e-06 0.18 0.22 0.15 0.22 4.0e-05 6.0e-06 2.1e-04 6.9e-06
10 NAcc gene expression Ankrd36 0.14 0.06 0.0e+00 0.25 0.26 0.26 0.26 1.2e-37 8.3e-39 9.1e-39 2.0e-39
11 RMTg gene expression Ankrd36 0.11 0.07 1.5e-03 0.07 0.1 0.08 0.09 4.8e-03 1.1e-03 3.9e-03 2.3e-03
12 OFC gene expression Ankrd36 0.36 0.19 1.2e-05 0.1 0.2 0.17 0.16 2.5e-03 2.1e-05 7.1e-05 9.8e-05
13 IC alternative polyA NM_001419749.1 0.1 0.07 2.9e-04 0.05 0.07 0.07 0.06 2.8e-03 7.2e-04 5.6e-04 2.1e-03
14 Brain alternative polyA XM_063273222.1 0.03 0.02 5.4e-04 0.02 0.03 0.02 0.03 3.8e-03 3.9e-04 3.2e-03 1.5e-03
15 Adipose alternative polyA NM_001419749.1 0.02 0.01 7.9e-03 0.01 0.01 0.01 0.01 1.4e-02 9.0e-03 7.0e-02 1.4e-02
16 IC gene expression Ankrd36 0.36 0.14 0.0e+00 0.4 0.42 0.4 0.41 4.0e-18 6.6e-19 5.7e-18 1.1e-18
17 BLA gene expression Ankrd36 0.23 0.1 1.8e-13 0.2 0.23 0.21 0.23 4.1e-11 2.0e-12 2.6e-11 2.2e-12
18 PL intron excision ratio chr14_84747111_84759503 0.02 0.02 5.2e-03 0.01 0.02 0.01 0.01 3.4e-02 3.0e-03 1.3e-02 1.6e-02
19 IC alternative polyA XM_063273222.1 0.18 0.12 1.4e-05 0.12 0.13 0.13 0.12 9.3e-06 5.5e-06 6.0e-06 6.7e-06
20 LHb alternative polyA NM_001419749.1 0.18 0.14 5.2e-03 0.03 0.04 0.03 0.04 7.5e-02 3.5e-02 7.5e-02 3.8e-02
21 NAcc isoform ratio NM_001419750.1 0.03 0.03 3.6e-04 0.02 0.02 0.01 0.01 5.7e-04 1.3e-03 2.0e-03 2.4e-03
22 IC isoform ratio XM_063273222.1 0.21 0.14 4.8e-04 0.09 0.09 0.05 0.11 1.0e-04 1.5e-04 4.0e-03 3.0e-05
23 BLA mRNA stability Ankrd36 0.12 0.08 1.3e-03 0.06 0.04 0.05 0.05 4.9e-04 3.4e-03 1.7e-03 1.5e-03
24 LHb gene expression Ankrd36 0.17 0.12 3.2e-03 0.04 0.09 0.21 0.08 4.9e-02 3.6e-03 1.1e-05 7.2e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density0.10.10.3-0.5-0.5-0.50.3-0.2-0.2-0.3-0.3-0.3-0.3-0.3-0.10.3-0.20.3-0.2-0.30.20.0-0.5-0.20.2-0.3-0.5
Area under the delay curve3.03.54.92.02.01.8-2.11.81.81.82.22.01.92.01.9-2.12.0-1.81.81.7-2.11.81.61.71.72.00.6
BMI with tail0.00.20.40.50.40.2-0.40.50.50.10.60.40.30.50.2-0.40.5-0.50.40.3-0.50.20.50.20.00.60.4
BMI without tail0.41.12.51.11.00.9-1.20.90.90.91.11.10.91.11.2-1.11.2-1.01.00.8-1.21.20.60.61.21.21.6
Body weight1.46.07.42.72.62.5-2.72.42.42.32.72.62.42.62.6-2.72.7-2.52.42.3-2.72.52.02.22.32.31.0
Weight adjusted by age0.30.50.90.80.80.4-0.80.50.50.70.70.70.60.70.9-0.60.7-0.50.70.6-0.70.90.30.80.90.90.5
Bone surface0.20.30.80.40.40.4-0.50.70.70.60.40.60.70.50.7-0.40.5-0.50.60.7-0.50.70.50.90.6-0.1-0.5
Bone volume0.10.30.50.30.30.3-0.50.70.70.50.40.50.60.50.6-0.40.5-0.50.60.6-0.50.70.40.70.60.0-0.2
Breakpoint value in progressive ratio session0.50.60.90.90.90.7-0.80.70.70.71.00.80.80.80.8-0.80.8-0.80.80.8-0.80.80.70.80.90.7-0.4
Number of licking bursts2.13.44.11.81.81.9-2.01.91.91.92.01.91.91.92.0-2.01.9-1.81.91.9-1.92.01.61.81.81.90.3
Context. condit. distance diff. score3.54.35.7-2.3-2.3-2.32.2-2.0-2.0-2.1-2.4-2.1-2.1-2.1-2.12.4-2.12.0-2.0-2.02.1-2.0-1.8-2.1-2.0-2.0-0.1
Locomotion velocity, session 10.20.21.30.30.30.40.30.20.20.3-0.1-0.20.2-0.1-0.50.1-0.4-0.0-0.20.20.4-0.70.60.1-1.2-0.9-0.3
Locomotion distance, session 10.60.81.8-1.1-1.1-1.10.7-1.0-1.0-0.8-0.4-0.9-1.0-0.8-0.80.5-0.61.0-1.0-1.20.5-0.7-1.4-0.90.20.1-0.9
Locomotion velocity, session 20.20.32.30.00.00.20.30.40.40.3-0.3-0.10.2-0.0-0.30.4-0.3-0.20.10.40.3-0.40.80.3-1.3-1.50.5
Locomotion distance, session 21.42.03.3-1.8-1.8-1.71.6-1.2-1.2-1.4-1.1-1.5-1.5-1.4-1.71.4-1.31.3-1.4-1.51.2-1.6-1.2-1.3-1.4-1.2-0.2
Locomotion velocity, session 32.42.74.5-2.1-2.1-2.01.8-1.4-1.4-1.8-1.7-1.7-1.8-1.7-1.61.6-1.61.7-1.6-1.71.5-1.5-1.7-1.7-1.0-1.3-0.9
Locomotion distance, session 30.20.20.6-0.3-0.3-0.2-0.30.80.80.20.50.40.30.40.4-0.30.5-0.50.60.4-0.60.60.30.60.60.3-0.4
Stereotopy head waving bouts, day 30.80.91.5-1.2-1.2-1.11.0-1.0-1.0-1.0-0.9-1.0-1.1-1.0-0.91.0-0.91.0-0.9-1.10.8-0.8-1.1-1.1-0.6-0.30.2
Stereotopy head waving duration, day 32.22.73.4-1.5-1.5-1.51.7-1.8-1.8-1.6-1.8-1.7-1.7-1.7-1.71.7-1.71.7-1.7-1.71.8-1.8-1.5-1.8-1.6-1.2-0.3
Locomotion velocity, session 70.20.20.60.30.30.3-0.40.80.80.60.40.50.50.50.4-0.30.4-0.50.50.5-0.50.40.50.60.1-0.10.3
Locomotion distance, session 70.20.30.7-0.7-0.7-0.70.6-0.1-0.1-0.3-0.5-0.5-0.4-0.4-0.60.7-0.50.3-0.4-0.40.4-0.5-0.2-0.2-0.9-0.90.1
Stereotopy head waving bouts, day 70.10.10.50.10.10.10.1-0.3-0.3-0.1-0.5-0.2-0.1-0.2-0.10.2-0.30.2-0.2-0.10.4-0.1-0.1-0.3-0.3-0.7-0.2
Stereotopy head waving duration, day 70.00.00.30.00.00.10.0-0.2-0.2-0.0-0.3-0.1-0.1-0.20.00.0-0.10.2-0.2-0.10.20.0-0.3-0.30.2-0.4-0.6
Locomotion velocity, session 81.61.97.4-1.5-1.5-1.31.5-0.8-0.8-1.0-1.6-1.3-1.1-1.3-1.51.7-1.41.0-1.1-1.01.4-1.5-0.6-1.0-2.0-2.70.4
Locomotion distance, session 87.410.713.1-3.6-3.6-3.63.5-3.2-3.2-3.3-3.5-3.4-3.4-3.4-3.53.6-3.33.2-3.3-3.33.3-3.3-2.9-3.3-3.1-3.2-0.2
Degree of sensitization distance2.22.34.5-1.1-1.1-1.11.6-1.5-1.5-1.1-1.7-1.6-1.3-1.6-1.71.8-1.71.5-1.6-1.31.8-1.8-1.0-1.4-2.1-1.80.3
Degree of sensitization stereotypy0.10.10.40.60.60.6-0.30.20.20.3-0.00.30.30.20.4-0.30.2-0.20.20.3-0.10.30.30.10.2-0.4-0.1
Conditioned locomotion1.11.22.5-1.4-1.4-1.51.0-1.1-1.1-1.3-0.5-1.1-1.3-1.1-1.00.8-0.81.2-1.1-1.40.7-0.9-1.6-1.10.10.6-1.1
Cocaine response after cond. corrected1.61.92.71.61.61.5-1.51.21.21.41.41.41.41.41.5-1.61.4-1.31.31.4-1.31.41.21.31.51.3-0.3
Cocaine response after cond. not corrected1.82.13.51.61.71.6-1.71.21.21.31.61.51.41.51.7-1.81.5-1.31.41.4-1.41.61.01.31.91.5-0.3
Cocaine response before conditioning0.30.40.8-0.8-0.7-0.80.5-0.8-0.8-0.7-0.5-0.6-0.7-0.6-0.50.5-0.50.7-0.7-0.80.5-0.5-0.9-0.7-0.0-0.2-0.2
Saline control response0.50.71.6-1.0-1.0-0.90.9-0.5-0.5-0.8-0.8-0.8-0.7-0.8-0.91.0-0.80.6-0.7-0.70.7-0.8-0.4-0.5-1.2-1.30.3
Bone: connectivity density0.20.30.6-0.7-0.7-0.60.5-0.5-0.5-0.4-0.6-0.5-0.5-0.5-0.40.5-0.50.5-0.4-0.50.5-0.3-0.6-0.4-0.1-0.8-0.6
Bone: cortical apparent density0.60.81.40.90.91.2-1.01.01.01.10.81.01.00.91.0-0.90.9-0.90.91.0-0.91.00.80.90.70.40.5
Bone: cortical area2.43.64.61.91.91.8-2.02.02.01.92.12.01.91.92.0-2.12.0-1.71.91.8-2.02.01.41.82.12.10.3
Bone: cortical porosity0.10.10.40.20.20.2-0.20.10.10.00.20.20.10.20.3-0.40.2-0.10.20.2-0.20.30.00.20.50.7-0.3
Bone: cortical porosity0.10.10.3-0.3-0.3-0.30.3-0.5-0.5-0.5-0.2-0.4-0.5-0.4-0.30.2-0.30.4-0.4-0.50.3-0.3-0.5-0.50.10.3-0.3
Bone: cortical thickness1.72.75.51.31.41.4-1.81.81.81.51.91.71.51.61.9-2.01.8-1.41.61.4-1.81.90.91.52.32.2-0.2
Bone: cortical thickness0.70.82.1-1.2-1.2-1.10.8-0.9-0.9-1.0-0.5-0.9-1.0-0.9-0.70.5-0.71.1-1.0-1.10.7-0.6-1.4-1.00.30.5-0.7
Bone: cortical tissue density0.70.91.50.91.01.2-1.01.01.01.20.81.01.11.01.0-0.91.0-1.01.01.0-0.91.00.90.90.70.40.6
Condit. Reinf. active minus inactive responses0.91.03.10.80.80.9-0.71.21.21.10.90.91.11.00.6-0.50.9-1.31.11.1-1.00.71.51.2-0.40.31.8
Condit. Reinf. active-inactive response ratio0.50.53.70.30.30.30.30.20.20.3-0.3-0.10.30.0-0.50.6-0.3-0.40.10.40.3-0.61.10.3-1.9-1.41.8
Condit. Reinf. active responses0.50.61.10.40.40.6-0.61.11.10.80.80.70.80.80.5-0.50.7-0.90.90.8-0.80.61.01.0-0.00.50.8
Condit. Reinf. inactive responses0.40.51.9-0.0-0.00.1-0.60.70.70.30.80.60.30.60.7-0.80.7-0.40.60.4-0.80.9-0.00.61.41.3-1.1
Incentive salience index mean1.21.52.21.01.01.0-1.11.41.41.31.41.21.21.31.0-1.01.3-1.51.41.2-1.41.11.51.40.30.91.4
Condit. Reinf. lever presses0.40.51.20.30.30.3-0.70.80.80.51.10.70.50.80.6-0.80.9-0.70.70.4-1.10.80.30.71.00.9-0.1
Condit. Reinf. active minus inactive responses0.50.60.9-0.9-0.8-0.90.8-0.8-0.8-0.8-0.8-0.8-0.7-0.8-0.80.9-0.80.7-0.8-0.80.7-0.8-0.7-0.5-0.7-0.9-0.4
Condit. Reinf. active-inactive response ratio0.00.00.1-0.1-0.1-0.20.1-0.1-0.1-0.00.0-0.1-0.1-0.0-0.20.2-0.00.0-0.1-0.2-0.0-0.2-0.00.0-0.3-0.30.1
Condit. Reinf. active responses0.70.91.5-1.1-0.9-1.01.0-1.0-1.0-0.9-1.0-1.0-0.8-0.9-1.11.0-1.00.9-1.0-0.90.9-1.1-0.8-0.7-1.0-1.2-0.5
Condit. Reinf. inactive responses0.91.12.1-1.1-0.9-0.91.1-1.1-1.1-1.0-1.2-1.1-0.9-1.1-1.21.1-1.21.0-1.1-0.91.2-1.2-0.7-0.9-1.2-1.5-0.4
Condit. Reinf. lever presses0.50.71.2-1.1-1.0-1.00.9-0.9-0.9-0.8-0.9-0.8-0.8-0.8-0.80.9-0.80.8-0.8-0.80.7-0.7-0.8-0.6-0.6-0.8-0.3
Condit. Reinf. lever reinforcers received0.50.71.3-1.0-0.8-0.80.9-0.9-0.9-0.8-0.8-0.8-0.7-0.8-0.90.9-0.80.8-0.8-0.80.8-0.9-0.6-0.5-0.9-1.1-0.4
Conditioned reinforcement - actives0.20.31.50.70.70.5-0.60.50.50.50.30.60.50.50.6-0.20.5-0.50.50.5-0.50.60.40.30.3-0.11.2
Conditioned reinforcement - inactives0.60.91.41.11.11.2-1.01.01.01.01.01.01.11.00.9-1.00.9-0.91.01.0-0.90.91.00.90.70.40.4
Conditioned locomotion0.91.26.81.11.11.0-1.21.01.01.00.81.21.01.11.2-0.51.2-1.01.01.0-1.21.10.80.80.7-0.12.6
Patch foraging indifference point 0 sec1.63.04.51.71.71.7-1.81.81.81.71.21.91.71.82.0-1.51.7-1.92.01.9-1.62.11.81.41.30.92.1
Patch foraging indifference point AUC0.10.10.60.40.30.3-0.20.20.20.30.00.20.30.20.2-0.10.2-0.30.30.4-0.10.20.40.3-0.3-0.60.8
Delay disc. indifference point, 0s delay1.11.22.11.21.21.0-1.21.01.01.01.21.11.11.11.2-1.41.1-0.91.01.0-1.01.20.70.91.41.4-0.6
Delay disc. indifference point, 16s delay2.02.23.21.81.81.5-1.61.51.51.51.71.51.61.61.3-1.41.5-1.61.51.5-1.51.21.61.40.81.21.4
Delay disc. indifference point, 2s delay1.71.96.01.01.01.0-1.51.01.01.11.71.41.11.31.5-1.81.5-1.11.31.0-1.61.60.50.92.22.5-1.2
Delay disc. indifference point, 24s delay1.31.42.11.11.11.3-1.21.21.21.31.51.21.21.31.0-1.31.3-1.31.31.1-1.41.11.21.10.81.20.9
Delay disc. indifference point, 4s delay3.03.24.81.81.81.6-2.01.61.61.72.11.91.71.91.9-2.12.0-1.71.71.5-2.01.91.21.52.12.20.3
Delay disc. indifference point, 8s delay0.91.01.81.11.11.0-1.11.11.11.01.31.11.11.10.9-1.21.1-1.00.90.9-1.20.80.81.00.81.10.1
Indifference point function ln k0.10.22.3-0.4-0.3-0.1-0.00.00.0-0.10.3-0.0-0.1-0.00.1-0.30.10.1-0.0-0.2-0.20.2-0.40.10.81.2-1.5
Indifference point function log k0.10.22.3-0.4-0.3-0.1-0.00.00.0-0.10.3-0.0-0.1-0.00.1-0.30.10.1-0.0-0.2-0.20.2-0.40.10.81.2-1.5
Patch foraging total patch changes 0 sec1.63.05.41.71.71.7-1.81.91.91.71.21.91.71.82.0-1.51.7-1.92.02.0-1.62.11.91.41.20.72.3
Patch foraging total patch changes 12 sec1.11.55.21.21.21.2-1.21.21.21.20.71.31.11.21.4-0.91.1-1.31.31.3-1.01.41.30.80.60.22.3
Patch foraging total patch changes 18 sec1.52.38.21.71.71.7-1.31.61.61.60.81.51.61.51.4-1.01.2-1.71.61.8-1.11.22.11.4-0.2-0.32.9
Patch foraging total patch changes 24 sec1.11.85.5-1.1-1.1-1.21.3-1.1-1.1-1.2-1.8-1.1-1.2-1.1-1.21.7-1.30.8-1.0-0.91.4-1.2-0.4-1.4-1.9-2.22.3
Patch foraging total patch changes 6 sec1.92.93.91.51.61.7-1.71.91.91.81.31.81.71.81.9-1.51.7-2.02.01.9-1.72.01.91.61.00.71.9
Patch foraging time to switch 0 sec0.30.61.0-0.8-0.7-0.80.7-1.0-1.0-0.9-0.7-0.8-0.9-0.8-0.80.8-0.70.9-0.9-0.90.8-0.8-0.9-1.0-0.4-0.30.2
Patch foraging water rate 0 sec1.32.83.91.61.61.7-1.61.91.91.81.51.71.81.71.7-1.61.6-1.91.91.9-1.61.72.01.70.91.00.9
Patch foraging water rate 12 sec0.00.10.20.10.10.1-0.20.40.40.30.20.30.30.30.3-0.20.3-0.40.40.3-0.30.40.40.30.10.1-0.3
Patch foraging water rate 18 sec0.20.31.5-0.5-0.4-0.4-0.1-0.5-0.5-0.50.2-0.1-0.5-0.20.0-0.20.10.4-0.3-0.6-0.20.1-1.0-0.81.11.2-1.1
Patch foraging water rate 24 sec0.00.10.30.20.30.3-0.10.20.20.40.20.10.30.2-0.1-0.00.1-0.20.10.2-0.1-0.10.40.0-0.5-0.30.3
Patch foraging water rate 6 sec0.30.51.00.50.50.5-0.70.60.60.70.90.70.70.70.7-0.80.8-0.60.60.5-0.80.70.30.61.01.0-0.7
Seeking ratio, delayed vs. immediate footshock0.10.10.40.10.1-0.20.1-0.6-0.6-0.4-0.0-0.3-0.4-0.2-0.40.3-0.10.4-0.5-0.50.1-0.5-0.5-0.5-0.2-0.20.4
Distance traveled before self-admin0.20.21.00.40.40.3-0.60.20.20.20.00.50.30.40.8-0.50.4-0.30.50.5-0.40.80.10.41.0-0.0-0.1
Distance traveled after self-admin0.10.10.90.00.0-0.1-0.4-0.1-0.1-0.10.00.3-0.10.20.5-0.20.4-0.00.2-0.0-0.30.7-0.40.10.90.3-0.1
Extensor digitorum longus weight3.212.815.53.63.63.5-3.83.63.63.73.63.83.73.73.9-3.73.8-3.63.83.6-3.83.93.13.83.43.01.1
Bone: elastic displacement0.40.50.9-0.8-0.8-0.60.6-0.9-0.9-0.9-0.8-0.7-0.8-0.7-0.50.5-0.70.8-0.7-0.80.7-0.4-0.9-1.0-0.1-0.4-0.1
Bone: elastic work0.20.21.30.10.10.2-0.4-0.0-0.00.10.30.3-0.10.20.5-0.50.4-0.10.2-0.0-0.40.7-0.4-0.31.11.10.3
Bone: endosteal estimation0.00.10.20.50.50.3-0.30.00.00.30.00.30.20.20.3-0.10.2-0.20.20.2-0.10.20.20.00.2-0.00.5
Bone: endosteal perimeter0.51.01.81.31.31.2-1.10.80.81.11.21.01.11.00.9-1.11.0-0.90.90.9-1.00.80.80.90.81.00.4
Epididymis fat weight0.31.21.70.80.81.0-1.21.01.01.11.21.21.11.11.2-1.31.2-1.11.11.1-1.31.30.81.21.30.90.2
Delta time in closed arm before/after self-admin9.58.910.6-2.9-2.9-3.23.0-3.2-3.2-3.2-2.9-3.1-3.0-3.1-3.12.7-3.13.2-3.3-3.23.0-3.2-3.1-2.9-2.2-1.9-2.5
Delta time in open arm before/after self-admin7.07.08.72.92.92.9-2.82.82.82.62.42.82.72.82.8-2.72.7-2.92.82.9-2.62.62.82.41.91.51.7
Diff in mean of infusions in LGA sessions0.10.10.2-0.2-0.2-0.30.2-0.4-0.4-0.4-0.1-0.3-0.4-0.2-0.30.1-0.20.3-0.3-0.40.1-0.2-0.4-0.50.00.10.0
Delay discount exponential model param3.03.44.7-1.9-1.9-1.82.0-1.8-1.8-1.8-2.2-1.9-1.9-2.0-1.82.1-2.01.8-1.8-1.72.0-1.8-1.5-1.7-1.7-2.0-0.6
Extinction: sum of active levers before priming0.20.22.10.20.20.3-0.20.30.30.30.20.30.30.30.1-0.10.3-0.40.30.3-0.30.10.50.6-0.4-0.51.4
Active lever presses in extinction session 60.20.23.1-0.2-0.2-0.40.1-0.5-0.5-0.5-0.0-0.3-0.4-0.3-0.2-0.1-0.20.5-0.4-0.40.2-0.2-0.6-0.20.50.3-1.8
Bone: final force0.30.40.80.50.50.5-0.60.80.80.60.50.70.50.60.7-0.50.7-0.70.70.6-0.60.80.60.40.60.60.9
Bone: final moment0.40.61.00.70.70.7-0.80.90.90.70.70.80.70.80.9-0.70.8-0.80.90.8-0.81.00.70.60.80.80.8
Food consumed during 24 hour testing period1.82.44.01.61.71.7-1.41.71.72.01.51.61.91.61.4-1.31.4-1.71.71.8-1.41.32.01.90.50.81.0
Glucose16.225.549.25.95.95.9-4.56.06.06.14.14.96.05.14.2-3.94.3-5.75.26.0-4.13.67.05.70.00.04.1
Heart weight0.20.31.20.30.30.6-0.10.70.70.60.10.40.60.40.20.00.2-0.70.60.7-0.30.21.10.6-0.8-0.61.1
Delay discount hyperbolic model param3.13.44.9-1.9-1.9-1.82.1-1.7-1.7-1.8-2.2-1.9-1.9-2.0-1.92.1-2.01.8-1.8-1.72.1-1.8-1.4-1.6-1.8-2.2-0.5
Intermittent access intake day 1-15 change0.71.44.51.01.01.2-1.01.41.41.20.91.11.31.21.0-0.71.0-1.31.21.3-1.01.01.51.40.1-0.22.1
Intermittent access intake escalation0.61.23.50.80.81.1-0.91.41.41.10.81.01.11.10.9-0.71.0-1.21.21.2-1.00.91.41.30.1-0.21.9
Intermittent access intake escalation 20.30.41.20.30.30.5-0.40.90.90.60.30.60.60.60.5-0.30.5-0.70.70.7-0.50.60.80.70.0-0.51.1
Intermitt. access day 1 inactive lever presses0.10.20.6-0.3-0.3-0.20.4-0.5-0.5-0.4-0.5-0.5-0.3-0.4-0.60.4-0.50.5-0.5-0.50.5-0.7-0.3-0.7-0.7-0.8-0.4
Intermitt. access day 15 inactive lever presses1.22.44.01.51.51.8-1.41.81.81.81.71.51.81.61.2-1.51.5-1.81.71.7-1.51.22.01.60.50.91.4
Intermitt. access escalation Index0.20.34.30.00.00.50.10.50.50.40.10.10.20.2-0.10.20.1-0.50.30.4-0.1-0.10.90.5-1.0-0.32.1
Intermittent access day 1 total infusions0.10.21.00.60.60.2-0.60.10.10.20.40.40.30.40.6-0.50.4-0.20.30.2-0.40.6-0.1-0.11.00.8-0.3
Intermittent access day 15 total infusions1.62.42.91.61.61.5-1.61.71.71.51.41.71.61.61.7-1.41.6-1.61.71.6-1.61.71.51.41.30.81.6
Intermittent access terminal intake (last 3 days)1.01.33.31.31.21.0-1.21.21.21.00.81.21.11.21.4-0.91.1-1.21.21.2-1.01.31.10.81.00.41.8
Intermittent access total infusions1.11.31.91.31.31.0-1.31.11.10.91.01.21.11.21.3-1.01.2-1.11.21.1-1.11.40.90.81.30.91.2
Intermittent access day 1 locomotion0.10.10.6-0.1-0.1-0.30.0-0.5-0.5-0.3-0.3-0.2-0.3-0.3-0.10.3-0.10.5-0.3-0.50.1-0.1-0.7-0.60.2-0.10.1
Intermittent access day 15 total locomotion0.71.32.81.41.41.1-1.31.01.01.11.11.21.21.21.2-0.91.2-1.11.11.1-1.21.10.90.90.90.41.7
Intermittent access total locomotion1.11.33.01.21.21.0-1.31.11.11.01.11.21.11.21.2-1.01.2-1.11.21.0-1.21.20.90.91.00.81.7
Intermittent access standard deviation0.30.71.5-0.9-0.9-0.90.8-0.8-0.8-0.7-1.2-0.8-0.7-0.9-0.61.0-0.90.9-0.7-0.70.9-0.5-0.8-0.9-0.5-1.20.3
Left kidney weight0.10.31.10.60.40.7-0.60.00.00.30.50.40.20.40.5-0.80.6-0.20.30.0-0.60.6-0.3-0.41.00.9-0.6
Right kidney weight0.10.32.4-0.2-0.3-0.1-0.3-0.1-0.1-0.20.20.1-0.40.00.4-0.60.40.2-0.0-0.4-0.40.7-1.0-0.71.61.2-0.9
Cocaine induced anxiety2.73.84.91.71.72.0-1.92.22.22.12.02.02.12.01.9-1.82.0-2.12.12.0-2.02.01.92.21.41.61.5
Post-drug Anxiety2.62.84.21.31.31.8-1.61.91.91.91.91.71.91.71.5-1.51.7-1.81.81.7-1.81.61.72.01.01.31.1
Baseline Anxiety0.20.20.7-0.4-0.4-0.20.5-0.5-0.5-0.2-0.2-0.5-0.4-0.4-0.60.4-0.40.4-0.5-0.50.3-0.7-0.4-0.2-0.7-0.2-0.8
Tail length2.59.913.33.03.03.1-3.53.03.03.13.33.33.03.33.5-3.43.5-3.03.32.9-3.53.62.32.83.53.11.6
Length with tail2.310.012.93.23.13.2-3.53.13.13.23.33.43.13.33.5-3.43.5-3.13.33.0-3.53.62.42.93.43.01.1
Length without tail0.30.91.30.90.90.8-1.01.01.00.91.11.00.91.01.0-1.01.1-1.01.00.9-1.21.00.81.00.90.8-0.2
Times rat made contact with spout0.30.42.60.30.30.40.20.60.60.6-0.50.00.50.0-0.10.4-0.4-0.40.30.70.4-0.31.20.6-1.4-1.60.2
Lifetime Intake0.91.11.81.21.20.8-1.21.01.00.80.91.10.91.11.3-1.01.1-0.91.11.0-1.01.30.70.61.31.00.9
Liver weight, left0.30.61.6-0.8-0.8-0.70.5-0.9-0.9-0.8-0.6-0.7-0.8-0.8-0.50.4-0.61.0-0.8-0.90.6-0.4-1.3-1.00.4-0.0-1.1
Liver weight, right1.01.73.4-1.2-1.2-1.61.2-1.5-1.5-1.4-1.0-1.4-1.4-1.4-1.20.9-1.21.6-1.5-1.61.2-1.1-1.8-1.5-0.1-0.1-1.4
Locomotor activity0.71.02.71.41.51.0-0.90.70.71.20.71.01.11.00.9-0.60.7-1.11.01.2-0.60.71.50.9-0.00.21.6
Locomotor testing distance0.30.51.20.70.80.6-0.90.30.30.80.70.80.60.71.0-0.80.8-0.60.70.6-0.70.90.40.41.11.10.7
Locomotor testing rearing1.42.84.01.71.81.7-1.71.61.62.01.41.81.81.71.9-1.61.7-1.81.81.9-1.61.81.71.61.21.01.4
Locomotion in novel chamber3.14.05.0-2.1-2.1-2.22.0-2.0-2.0-2.1-2.1-2.1-2.1-2.1-1.81.9-2.12.2-2.1-2.12.1-1.8-2.2-2.1-1.2-1.4-2.1
Locomotion in novel chamber post-restriction2.13.55.7-1.7-1.8-1.72.1-1.7-1.7-1.7-1.6-2.1-1.9-2.0-2.31.7-2.01.9-2.1-1.92.0-2.4-1.5-1.8-1.9-1.3-1.5
Fecal boli incidents, locomotor time 10.10.10.2-0.4-0.4-0.10.4-0.3-0.3-0.1-0.1-0.4-0.3-0.3-0.40.3-0.30.3-0.4-0.40.3-0.5-0.3-0.3-0.30.0-0.5
Change in fecal boli incidents, locomotor task0.30.32.20.40.40.5-0.10.60.60.60.00.30.50.30.1-0.00.2-0.50.40.5-0.20.00.80.5-0.7-0.81.5
Time >=10cm from walls, locomotor time 10.10.10.3-0.1-0.10.20.2-0.1-0.10.2-0.2-0.20.1-0.2-0.20.1-0.40.3-0.3-0.00.4-0.4-0.1-0.0-0.4-0.6-0.3
Bouts of movement, locomotor time 10.50.61.80.90.90.8-0.50.80.80.80.30.60.80.60.5-0.20.4-0.80.70.9-0.40.31.21.0-0.5-0.51.3
Total resting periods, locomotor time 10.20.21.60.50.50.4-0.00.40.40.40.00.20.40.2-0.00.20.0-0.40.30.5-0.0-0.20.80.5-0.9-0.81.3
Rest time, locomotor task time 10.10.10.40.20.20.3-0.00.40.40.40.10.10.30.1-0.10.1-0.0-0.10.10.3-0.0-0.10.30.5-0.4-0.60.4
Distance moved, locomotor task time 10.20.30.60.40.40.5-0.70.30.30.40.50.60.40.60.7-0.60.7-0.50.60.4-0.70.80.20.10.70.70.6
Vertical activity count, locomotor time 10.10.10.50.40.40.2-0.50.10.10.20.30.40.20.30.5-0.40.4-0.30.30.2-0.30.50.2-0.10.50.70.1
Time >=10cm from walls, locomotor time 20.20.30.8-0.2-0.2-0.30.4-0.8-0.8-0.3-0.3-0.5-0.4-0.5-0.60.3-0.60.7-0.8-0.60.6-0.9-0.6-0.8-0.5-0.4-0.7
Bouts of movement, locomotor time 20.10.11.5-0.1-0.1-0.1-0.2-0.0-0.0-0.20.70.1-0.10.3-0.0-0.20.5-0.20.1-0.3-0.60.1-0.2-0.10.51.20.2
Total resting periods, locomotor time 20.10.11.10.00.00.0-0.20.10.1-0.00.70.20.10.40.0-0.20.5-0.30.2-0.1-0.70.20.00.10.41.00.6
Rest time, locomotor task time 20.10.10.8-0.4-0.4-0.10.4-0.2-0.2-0.1-0.4-0.3-0.2-0.3-0.30.5-0.30.1-0.1-0.10.3-0.30.10.1-0.5-0.70.9
Distance moved, locomotor task time 20.10.10.1-0.0-0.0-0.20.2-0.3-0.3-0.2-0.3-0.3-0.2-0.3-0.20.3-0.30.4-0.4-0.30.3-0.3-0.3-0.3-0.3-0.4-0.1
Vertical activity count, locomotor time 20.10.11.40.10.1-0.10.0-0.1-0.1-0.1-0.1-0.2-0.1-0.2-0.1-0.0-0.30.4-0.3-0.20.3-0.2-0.3-0.20.20.0-1.2
Light reinforcement 10.10.20.70.00.10.3-0.50.50.50.40.30.50.30.40.6-0.40.6-0.30.40.3-0.60.8-0.10.20.90.0-0.1
Light reinforcement 20.10.21.20.30.30.2-0.50.20.20.10.60.30.10.30.4-0.60.5-0.00.1-0.1-0.50.4-0.5-0.11.00.4-1.1
Bone: marrow area0.00.00.10.40.40.2-0.2-0.1-0.10.1-0.10.10.10.10.2-0.00.1-0.10.10.1-0.00.10.1-0.10.1-0.10.3
Bone: maximum diameter4.07.49.33.13.03.0-2.82.92.93.02.82.83.02.92.6-2.72.7-2.92.82.9-2.72.52.93.01.71.71.2
Bone: maximum force0.20.30.70.30.40.4-0.60.60.60.50.50.60.40.50.7-0.50.6-0.50.60.5-0.60.80.30.40.80.60.4
Bone: maximum moment0.30.51.20.50.50.5-0.80.70.70.70.70.80.60.70.9-0.70.8-0.60.70.6-0.81.00.30.61.10.90.3
Mean time between licks in bursts0.30.71.80.91.01.0-0.61.01.01.10.80.71.00.80.5-0.60.6-1.00.81.0-0.50.31.41.1-0.30.20.5
Mean num. licks in bursts1.72.67.3-1.3-1.4-1.41.8-1.2-1.2-1.3-2.0-1.6-1.3-1.6-1.82.0-1.81.3-1.5-1.11.9-1.9-0.6-1.2-2.5-2.70.0
Cd content in liver0.60.61.20.90.80.8-0.70.80.80.90.70.80.90.80.7-0.60.7-0.90.90.9-0.70.61.10.90.20.60.5
Co content in liver0.30.41.70.40.30.6-0.60.40.40.50.40.70.40.60.8-0.50.7-0.70.70.5-0.70.90.40.40.60.71.3
Cu content in liver0.20.20.60.50.50.6-0.40.50.50.70.40.40.60.40.4-0.40.3-0.50.50.6-0.30.30.70.5-0.00.20.2
Fe content in liver2.12.53.6-1.6-1.6-1.61.7-1.6-1.6-1.6-1.4-1.7-1.6-1.6-1.91.6-1.61.5-1.7-1.71.5-1.9-1.3-1.6-1.7-1.6-0.5
K content in liver2.01.96.61.11.01.1-1.51.11.11.11.61.31.01.31.5-1.81.5-0.91.10.9-1.61.60.30.92.62.3-0.8
Mg content in liver0.40.41.10.50.40.5-0.60.60.60.70.70.60.50.60.7-0.80.6-0.50.60.5-0.70.80.20.51.11.1-0.6
Mn content in liver0.30.31.60.10.20.1-0.50.50.50.20.50.40.20.40.6-0.60.6-0.20.40.2-0.60.8-0.20.31.30.9-0.6
Na content in liver2.42.63.21.81.81.7-1.71.71.71.71.81.71.71.71.5-1.71.7-1.71.61.6-1.71.51.61.71.21.00.4
Rb content in liver1.72.02.71.51.51.4-1.61.41.41.61.41.51.51.41.7-1.51.5-1.31.41.4-1.41.61.11.31.61.30.1
Se content in liver1.21.44.50.60.80.6-1.31.11.10.71.41.20.81.21.4-1.41.3-1.01.20.9-1.41.60.41.02.11.9-0.2
Sr content in liver4.23.64.72.02.02.1-1.91.91.92.02.21.92.02.01.8-2.02.0-2.01.91.9-2.01.72.01.91.31.90.8
Zn content in liver0.40.41.60.50.40.6-0.70.40.40.70.90.60.50.60.6-0.90.8-0.40.50.3-0.90.70.00.51.11.30.0
Bone: minimum diameter0.00.10.2-0.0-0.1-0.30.1-0.2-0.2-0.2-0.1-0.2-0.3-0.2-0.10.1-0.10.3-0.3-0.30.1-0.1-0.5-0.30.30.2-0.2
Time in familiar zone, hab. session 10.10.10.4-0.5-0.5-0.60.4-0.2-0.2-0.5-0.4-0.3-0.4-0.3-0.30.6-0.30.3-0.3-0.30.2-0.2-0.3-0.2-0.3-0.60.2
Time in novel zone, hab. session 10.40.40.60.80.80.8-0.70.50.50.80.50.60.70.60.8-0.80.5-0.50.60.7-0.40.70.50.50.80.70.1
Total zone transitions, hab. session 10.00.00.20.10.10.2-0.10.30.30.40.20.10.30.20.1-0.20.1-0.20.20.2-0.20.10.20.4-0.0-0.3-0.2
Total locomotion distance, hab. session 10.10.20.50.20.20.2-0.40.40.40.40.60.40.40.40.4-0.50.5-0.20.30.2-0.50.40.00.60.70.2-0.2
Locomotion velocity, hab. session 10.00.00.20.00.00.0-0.10.10.10.10.30.00.10.1-0.1-0.20.10.0-0.00.0-0.1-0.1-0.00.30.1-0.2-0.4
Time in familiar zone, hab. session 22.12.22.9-1.3-1.3-1.41.5-1.6-1.6-1.7-1.6-1.5-1.6-1.4-1.51.7-1.41.4-1.5-1.51.5-1.6-1.2-1.7-1.6-1.50.6
Time in novel zone, hab. session 22.93.04.01.51.51.6-1.71.91.92.01.71.81.91.71.9-1.81.7-1.71.81.9-1.71.91.62.01.71.6-0.4
Total zone transitions, hab. session 20.81.01.90.70.70.8-1.01.21.21.11.41.01.01.10.9-1.21.1-1.01.00.9-1.20.90.71.11.01.1-0.3
Total locomotion distance, hab. session 20.91.12.10.80.80.9-1.01.31.31.21.41.11.11.20.9-1.11.2-1.11.11.0-1.30.90.91.40.80.90.3
Locomotion velocity, hab. session 21.11.42.70.90.91.0-1.21.31.31.31.61.21.21.31.0-1.31.4-1.21.21.0-1.51.00.91.41.01.10.3
Novel to familiar place preference ratio0.80.91.71.31.31.3-0.81.11.11.20.70.91.10.80.8-0.80.6-0.90.81.1-0.60.51.21.00.00.00.0
Novelty place preference0.90.91.91.41.41.4-0.81.21.21.30.70.91.20.90.8-0.90.6-0.90.91.2-0.60.61.31.10.1-0.0-0.1
Time in novel zone, NPP test0.90.91.71.31.31.3-0.81.21.21.30.70.91.20.90.8-0.80.6-0.90.91.2-0.50.61.31.10.10.1-0.1
Total zone transitions, NPP test0.40.61.4-1.1-1.1-1.10.6-0.7-0.7-0.8-0.3-0.7-0.9-0.7-0.70.4-0.50.8-0.7-1.00.3-0.5-1.2-0.70.30.1-0.8
Total locomotion distance, NPP test0.10.20.7-0.6-0.6-0.60.2-0.2-0.2-0.30.4-0.3-0.3-0.2-0.3-0.1-0.00.4-0.3-0.5-0.1-0.2-0.7-0.10.50.6-0.8
Locomotion velocity, NPP test0.10.10.4-0.4-0.4-0.3-0.0-0.0-0.0-0.10.5-0.1-0.10.0-0.1-0.30.20.2-0.1-0.3-0.3-0.1-0.50.10.60.6-0.6
Intraocular pressure0.30.41.30.60.70.8-0.50.70.70.80.60.60.80.60.3-0.50.5-0.70.60.7-0.50.31.00.8-0.3-0.21.1
Delta distance traveled before/after self-admin0.70.71.0-0.9-0.9-0.80.8-0.9-0.9-0.8-0.7-0.9-0.8-0.8-0.90.8-0.80.9-0.9-1.00.7-0.9-1.0-0.9-0.7-0.5-0.5
Delta ambulatory time before/after self-admin0.60.81.3-1.0-1.0-0.90.9-0.9-0.9-0.8-0.6-0.9-0.8-0.9-1.00.8-0.80.9-0.9-1.00.7-0.9-1.0-0.8-0.8-0.5-1.1
Parametrial fat weight2.14.99.72.62.72.6-1.92.52.52.42.32.12.52.31.5-1.72.0-2.62.22.4-2.01.23.12.4-0.20.42.4
Pavlov. Cond. lever latency0.20.30.70.80.80.8-0.50.40.40.60.20.50.60.50.5-0.40.4-0.60.50.7-0.30.30.80.4-0.1-0.20.7
Pavlov. Cond. magazine entry latency2.12.74.3-2.0-2.0-2.11.8-1.5-1.5-1.7-1.6-1.7-1.8-1.7-1.71.8-1.71.7-1.6-1.71.6-1.6-1.6-1.5-1.2-1.0-0.8
Pavlov. Cond. change in total contacts1.21.31.80.80.80.8-1.11.31.31.11.31.21.11.21.1-1.01.2-1.31.31.1-1.31.21.11.30.91.10.7
Pavlov. Cond. index score1.82.34.2-2.0-2.0-2.11.6-1.4-1.4-1.7-1.3-1.6-1.7-1.5-1.51.6-1.41.5-1.5-1.71.3-1.3-1.7-1.4-0.8-0.7-0.7
Pavlov. Cond. latency score1.51.83.3-1.8-1.8-1.81.4-1.3-1.3-1.6-1.1-1.4-1.6-1.4-1.41.3-1.21.4-1.3-1.51.1-1.2-1.5-1.3-0.6-0.5-0.8
Pavlov. Cond. lever contacts0.60.81.8-1.3-1.3-1.30.9-0.8-0.8-1.0-0.6-0.9-1.0-0.8-0.90.8-0.70.9-0.8-1.00.5-0.6-1.1-0.8-0.2-0.2-0.6
Pavlov. Cond. magazine entry number2.12.64.82.22.22.2-1.81.31.31.71.61.71.71.71.7-1.91.6-1.51.51.6-1.51.41.51.41.31.10.4
Pavlov. Cond. intertrial magazine entries0.50.63.90.70.70.6-0.90.30.30.51.10.70.50.70.7-1.20.8-0.40.40.3-0.90.7-0.10.31.52.0-0.6
Pavlov. Cond. lever-magazine prob. diff.2.22.75.0-2.2-2.2-2.21.7-1.5-1.5-1.8-1.4-1.7-1.9-1.7-1.71.7-1.51.7-1.6-1.91.4-1.4-1.9-1.5-0.8-0.7-0.9
Pavlov. Cond. response bias0.91.12.7-1.7-1.7-1.61.1-0.8-0.8-1.1-0.8-1.0-1.2-1.0-1.01.1-0.91.0-0.9-1.10.7-0.7-1.2-0.8-0.3-0.2-0.6
Pavlov. Cond. lever latency3.54.88.22.22.12.0-2.52.12.12.02.52.32.02.22.4-2.52.4-1.92.11.9-2.42.51.31.82.92.6-0.2
Pavlov. Cond. magazine entry latency0.10.10.3-0.5-0.5-0.30.3-0.2-0.20.1-0.4-0.3-0.1-0.3-0.20.3-0.30.3-0.2-0.20.3-0.2-0.20.0-0.3-0.6-0.1
Pavlov. Cond. change in total contacts0.20.30.7-0.5-0.4-0.40.6-0.6-0.6-0.2-0.6-0.6-0.4-0.5-0.60.6-0.60.5-0.5-0.40.6-0.7-0.2-0.4-0.8-0.7-0.0
Pavlov. Cond. index score1.21.62.8-1.4-1.3-1.11.4-1.2-1.2-1.0-1.4-1.3-1.1-1.3-1.41.4-1.41.1-1.2-1.11.4-1.4-0.8-0.9-1.6-1.7-0.1
Pavlov. Cond. latency score1.41.92.5-1.6-1.5-1.41.5-1.3-1.3-1.1-1.5-1.4-1.3-1.4-1.51.5-1.51.3-1.3-1.21.5-1.4-1.0-1.1-1.5-1.5-0.4
Pavlov. Cond. lever contacts3.85.38.2-2.3-2.2-2.22.6-2.2-2.2-2.2-2.6-2.4-2.1-2.4-2.52.6-2.52.1-2.2-2.02.5-2.6-1.5-2.0-2.9-2.60.1
Pavlov. Cond. magazine entry number0.10.21.40.40.30.1-0.40.10.1-0.10.60.30.00.30.3-0.50.4-0.10.1-0.0-0.40.3-0.2-0.10.91.2-0.4
Pavlov. Cond. intertrial magazine entries0.00.00.20.10.10.0-0.10.10.1-0.30.20.10.00.20.0-0.20.2-0.20.10.1-0.20.10.10.10.10.40.1
Pavlov. Cond. lever-magazine prob. diff.1.31.83.0-1.5-1.4-1.31.5-1.2-1.2-1.1-1.6-1.4-1.2-1.4-1.41.5-1.51.3-1.3-1.11.5-1.4-0.9-1.0-1.6-1.7-0.2
Pavlov. Cond. response bias1.92.55.0-1.6-1.5-1.31.8-1.5-1.5-1.3-2.0-1.6-1.4-1.6-1.71.9-1.81.4-1.5-1.21.8-1.8-0.8-1.2-2.2-2.20.4
Time in closed arm before self-admin0.20.31.00.60.60.4-0.70.40.40.40.50.60.30.50.8-0.60.6-0.50.60.4-0.60.80.20.11.00.50.1
Time in closed arm after self-admin2.62.73.6-1.6-1.6-1.91.6-1.9-1.9-1.9-1.6-1.7-1.8-1.7-1.61.6-1.61.8-1.8-1.91.6-1.6-1.8-1.8-1.1-1.2-0.6
Time in open arm before self-admin0.80.91.2-1.1-1.1-0.91.0-1.0-1.0-0.9-0.8-1.0-0.8-1.0-1.00.9-1.01.0-1.0-0.90.9-0.9-0.9-0.6-0.7-0.9-1.0
Time in open arm after self-admin0.60.71.41.11.11.0-0.80.90.90.90.70.90.90.90.7-0.70.8-1.00.81.0-0.70.61.20.90.2-0.10.6
Bone: periosteal estimation0.61.31.91.41.41.2-1.31.11.11.21.21.21.21.21.3-1.31.2-1.01.11.1-1.11.20.91.01.31.10.3
Bone: periosteal perimeter1.32.33.21.81.81.7-1.71.51.51.61.81.61.61.61.5-1.71.6-1.41.41.4-1.61.41.21.31.41.50.4
Bone: post-yield work0.00.10.20.10.20.2-0.20.40.40.30.20.20.40.20.3-0.20.2-0.20.20.3-0.20.20.20.50.3-0.0-0.1
Progressive ratio test 1 active lever presses0.50.61.00.90.90.6-1.00.60.60.70.80.90.70.80.9-0.70.9-0.70.80.7-0.90.90.50.50.91.01.0
Progressive ratio test 1 breakpoint0.50.61.30.90.80.7-0.90.70.70.70.80.90.70.80.9-0.70.9-0.70.80.7-0.90.90.50.50.81.01.1
Progressive ratio test 1 inactive lever presses4.05.77.92.52.52.6-2.62.32.32.42.82.52.52.52.3-2.72.6-2.42.42.2-2.62.32.02.32.22.60.2
Progressive ratio test 2 active lever presses0.80.91.21.11.10.9-1.11.01.00.80.91.01.01.01.1-0.90.9-0.91.01.0-0.91.10.90.70.90.60.9
Progressive ratio test 2 breakpoint0.70.70.91.01.00.8-0.90.90.90.70.80.90.90.91.0-0.80.8-0.90.90.9-0.80.90.80.70.80.50.9
Progressive ratio test 2 inactive lever presses1.01.72.51.51.51.3-1.41.41.41.31.51.41.41.41.2-1.11.4-1.41.31.2-1.41.11.31.20.80.61.6
Incentive Sensitization - Responses0.20.30.40.60.60.5-0.50.60.60.50.50.50.60.60.5-0.50.5-0.60.50.6-0.50.40.60.50.3-0.00.6
Incentive Sensitization - Breakpoint0.20.20.40.50.50.4-0.40.50.50.40.40.50.50.50.4-0.40.4-0.50.40.5-0.30.30.60.50.2-0.10.6
Sum of active levers in priming session hrs 5-60.60.62.40.30.30.7-0.60.60.60.60.90.60.50.60.6-1.00.7-0.60.70.5-0.80.70.40.61.11.5-1.3
Progressive ratio0.10.20.6-0.2-0.2-0.40.2-0.7-0.7-0.8-0.4-0.3-0.6-0.3-0.30.4-0.20.4-0.4-0.60.2-0.2-0.7-0.80.00.20.5
Food seeking constrained by brief footshock2.93.57.21.81.71.9-2.11.61.61.62.11.91.71.92.1-2.42.1-1.51.81.5-2.12.20.91.62.72.0-1.1
Seeking ratio, punishment vs. effort0.91.42.30.80.81.1-1.11.21.21.31.41.11.11.11.1-1.51.2-1.11.11.0-1.31.20.81.31.41.2-1.0
Retroperitoneal fat weight0.52.03.91.61.61.7-1.21.51.51.61.51.31.61.50.9-1.11.3-1.71.41.5-1.40.72.01.4-0.30.21.6
Reaction time number correct0.00.10.30.00.10.1-0.00.20.20.3-0.10.10.30.10.10.10.0-0.30.20.3-0.00.10.50.5-0.4-0.60.2
Reaction time mean minus median0.92.15.2-1.2-1.2-1.01.6-1.4-1.4-1.1-1.7-1.5-1.1-1.5-1.61.6-1.71.2-1.4-1.01.7-1.7-0.6-1.0-2.2-2.30.7
Reaction time mean minus median AUC0.61.63.2-1.2-1.2-1.01.4-1.3-1.3-1.0-1.6-1.3-1.1-1.4-1.31.3-1.51.2-1.2-1.01.6-1.4-0.7-1.0-1.6-1.80.2
Reaction time num false alarms0.40.53.2-0.1-0.1-0.1-0.60.60.60.20.90.60.20.60.7-0.70.8-0.50.70.3-0.91.00.00.51.41.8-0.4
Reaction time num false alarms AUC0.30.53.7-0.3-0.3-0.3-0.50.40.4-0.10.80.5-0.00.50.6-0.60.7-0.30.50.1-0.91.0-0.30.31.61.9-0.5
Reaction time trials correct on left0.00.10.30.00.10.1-0.00.20.20.3-0.10.10.30.10.10.10.0-0.30.20.3-0.00.10.50.5-0.4-0.60.2
Reaction time trials on left0.00.10.4-0.00.10.00.00.10.10.2-0.10.10.20.10.00.2-0.0-0.20.20.30.00.00.40.4-0.4-0.60.2
Reaction time mean0.71.01.7-0.8-0.8-0.71.1-1.2-1.2-1.0-1.0-1.1-1.0-1.0-1.21.0-1.10.9-1.1-1.01.1-1.3-0.7-1.1-1.3-1.10.5
Reaction time mean AUC1.01.62.2-1.1-1.1-1.01.3-1.4-1.4-1.3-1.2-1.3-1.3-1.3-1.41.2-1.31.2-1.3-1.31.3-1.5-1.0-1.3-1.3-1.20.2
Median of all reaction times0.40.60.9-0.6-0.6-0.50.7-0.9-0.9-0.8-0.6-0.8-0.8-0.7-0.90.6-0.70.7-0.8-0.80.7-0.9-0.6-0.9-0.8-0.60.4
Reaction time omissions1.42.12.7-1.5-1.5-1.41.5-1.6-1.6-1.5-1.5-1.4-1.6-1.4-1.41.5-1.41.3-1.4-1.41.4-1.4-1.2-1.5-1.3-1.30.9
Reaction time false alarm rate0.40.54.3-0.2-0.2-0.2-0.50.40.4-0.10.90.4-0.00.40.6-0.70.7-0.30.40.0-0.80.9-0.40.11.72.1-0.6
Reaction time premature initiation rate2.53.44.9-2.1-2.1-2.01.8-2.0-2.0-2.0-1.8-1.9-2.0-2.0-1.81.6-1.82.1-1.9-2.01.8-1.6-2.2-2.0-0.9-1.0-1.3
Reaction time premature initiations1.11.92.8-1.7-1.7-1.51.4-1.5-1.5-1.4-1.4-1.4-1.4-1.5-1.31.3-1.41.5-1.4-1.41.4-1.2-1.5-1.2-0.8-1.0-1.0
Std. dev. reaction times1.12.04.0-1.2-1.2-1.01.5-1.5-1.5-1.2-1.5-1.4-1.2-1.4-1.61.5-1.61.2-1.4-1.21.6-1.7-0.7-1.2-2.0-1.71.0
Reaction time trials completed0.00.10.4-0.00.10.00.00.10.10.2-0.10.10.20.10.00.2-0.0-0.20.20.30.00.00.40.4-0.4-0.60.2
Reaction time trials AUC0.00.10.30.10.20.1-0.10.20.20.30.00.20.30.20.20.00.1-0.30.30.4-0.10.20.50.6-0.2-0.40.2
Run reversals in cocaine runway, females0.70.71.1-0.9-1.0-1.00.9-0.8-0.8-1.0-0.7-0.9-0.9-0.8-1.10.9-0.80.8-0.9-0.90.7-1.0-0.7-0.9-0.8-0.3-0.2
Run reversals in cocaine runway, males0.40.40.70.70.70.8-0.70.60.60.60.40.70.70.60.7-0.70.6-0.50.60.7-0.50.70.50.60.50.20.1
Latency to leave start box in cocaine runway0.20.21.30.10.10.1-0.40.20.2-0.00.40.40.00.40.5-0.60.5-0.30.30.1-0.50.5-0.0-0.20.81.1-0.2
Latency to leave start box in cocaine runway, F1.11.23.90.80.90.9-1.21.01.00.91.11.10.81.11.3-1.41.2-1.01.00.8-1.21.40.50.61.62.0-0.6
Latency to leave start box in cocaine runway, M0.70.61.3-0.7-0.7-0.90.7-1.0-1.0-1.1-0.7-0.7-0.9-0.7-0.80.8-0.70.6-0.8-0.90.7-0.8-0.7-1.0-0.7-0.80.3
Std. dev. time between licks in bursts0.00.00.3-0.1-0.1-0.10.10.10.1-0.0-0.1-0.1-0.0-0.0-0.10.2-0.1-0.10.00.10.1-0.10.20.1-0.4-0.30.6
Total sessions with >9 infusions0.60.81.6-0.7-0.7-1.10.7-1.1-1.1-1.0-1.1-0.8-1.0-0.9-0.50.9-0.81.1-0.9-0.90.9-0.5-1.2-1.0-0.0-0.6-0.9
Short access day 1 total inactive lever presses3.64.76.32.42.52.3-2.42.02.01.92.22.32.02.22.4-2.52.3-2.12.22.1-2.22.41.72.12.32.00.6
Short access day 10 total inactive lever presses0.10.20.30.30.40.5-0.40.50.50.40.40.40.40.40.3-0.50.4-0.40.40.3-0.40.30.30.40.20.1-0.5
Short access day 1 total infusions0.40.61.5-0.7-0.7-0.60.5-1.0-1.0-0.9-0.9-0.7-0.9-0.8-0.40.6-0.71.0-0.8-0.90.7-0.4-1.2-1.00.1-0.4-0.6
Short access day 10 total infusions0.20.30.9-0.2-0.2-0.70.2-0.7-0.7-0.6-0.6-0.4-0.6-0.5-0.10.4-0.40.6-0.5-0.50.5-0.2-0.8-0.90.40.0-0.5
Short access total infusions0.10.10.90.30.3-0.1-0.4-0.1-0.1-0.1-0.00.2-0.00.10.5-0.20.20.10.10.0-0.10.6-0.3-0.21.00.5-0.3
Short access day 1 locomotion0.81.02.8-1.1-1.1-1.00.7-1.2-1.2-1.0-1.0-0.9-1.1-1.0-0.60.9-0.81.3-1.0-1.20.8-0.4-1.7-1.10.2-0.4-1.3
Short access day 10 total locomotion0.71.22.7-0.9-0.9-1.10.8-1.4-1.4-1.1-1.3-1.0-1.2-1.1-0.81.2-0.91.3-1.1-1.30.9-0.7-1.6-1.5-0.5-1.2-0.1
Short access total locomotion1.21.52.9-1.1-1.1-1.31.0-1.5-1.5-1.3-1.5-1.1-1.3-1.2-0.81.3-1.11.4-1.2-1.31.1-0.7-1.7-1.5-0.4-1.0-0.6
One hour access (0.3 mA shock)1.31.52.01.41.41.1-1.41.31.31.01.21.31.21.31.4-1.11.3-1.21.31.2-1.31.41.01.11.20.81.1
Compulsive drug intake1.72.02.8-1.3-1.3-1.51.5-1.5-1.5-1.7-1.5-1.5-1.5-1.5-1.41.4-1.51.5-1.5-1.51.5-1.5-1.4-1.4-1.2-0.9-1.0
One hour access (shock baseline)1.11.72.31.51.51.2-1.51.31.31.21.31.41.31.41.4-1.11.4-1.31.41.3-1.31.41.21.11.10.71.2
Social response proportion1.31.52.51.51.41.5-1.11.61.61.61.51.11.41.30.8-1.21.2-1.31.11.2-1.20.61.51.20.20.80.1
Social responses1.82.43.81.61.61.7-1.41.71.71.91.61.51.81.71.2-1.31.5-1.81.61.6-1.61.12.01.60.20.51.5
Social time0.10.21.00.30.30.4-0.10.30.30.50.40.20.40.4-0.0-0.10.3-0.50.30.3-0.3-0.10.60.4-0.7-0.21.0
Soleus weight0.72.25.61.61.61.4-1.71.11.11.11.81.51.21.41.7-1.91.6-1.11.21.0-1.61.70.51.02.32.4-0.0
Bone: stiffness0.00.10.2-0.2-0.2-0.30.3-0.1-0.1-0.1-0.4-0.3-0.2-0.3-0.20.3-0.30.3-0.3-0.20.4-0.3-0.2-0.3-0.3-0.30.1
Tibialis anterior weight1.23.94.82.12.21.9-2.12.12.12.12.02.12.12.12.1-1.82.0-2.12.12.1-2.02.12.02.21.51.11.2
Time to tail flick, vehicle, before self-admin0.10.10.3-0.0-0.0-0.2-0.20.00.0-0.00.40.1-0.00.20.1-0.30.3-0.00.1-0.1-0.40.2-0.30.00.50.4-0.5
Time to tail flick, vehicle, after self-admin0.10.20.4-0.6-0.6-0.50.4-0.4-0.4-0.5-0.2-0.4-0.5-0.3-0.50.5-0.20.3-0.4-0.60.1-0.4-0.5-0.6-0.2-0.20.4
Time to tail flick, test, before self-admin0.10.10.3-0.0-0.0-0.10.1-0.3-0.3-0.2-0.3-0.1-0.3-0.20.1-0.0-0.30.2-0.2-0.10.40.1-0.2-0.30.20.1-0.5
Time to tail flick, test, after self-admin2.93.04.31.61.61.7-1.91.61.61.62.11.81.61.81.8-1.91.9-1.71.81.6-2.01.91.31.82.01.7-0.1
Delta time to tail flick, vehicle, before/after SA0.20.20.4-0.3-0.3-0.30.5-0.6-0.6-0.4-0.5-0.5-0.5-0.5-0.60.5-0.50.5-0.6-0.50.5-0.6-0.4-0.6-0.5-0.5-0.3
Delta time to tail flick, test, before/after SA1.21.32.01.01.01.1-1.11.31.31.21.41.21.21.30.9-0.91.3-1.31.21.0-1.40.91.11.40.60.51.3
Tibia length0.20.51.6-0.5-0.5-0.70.2-0.9-0.9-0.8-0.0-0.4-0.8-0.5-0.20.1-0.20.7-0.6-0.90.2-0.1-1.3-1.11.01.0-0.3
Ambulatory time before self-admin0.50.82.20.90.90.7-1.10.70.70.60.51.00.70.91.3-1.00.9-0.70.90.9-0.91.30.40.71.50.40.3
Ambulatory time after self-admin0.10.10.60.10.1-0.0-0.3-0.1-0.1-0.10.00.2-0.00.10.4-0.30.30.00.1-0.0-0.30.5-0.4-0.00.80.1-0.8
Bone: tissue strength0.10.10.40.30.30.3-0.0-0.0-0.00.2-0.40.10.20.00.20.1-0.1-0.10.10.30.30.10.4-0.0-0.4-0.60.5
Total heroin consumption0.00.00.1-0.2-0.2-0.40.0-0.3-0.3-0.20.1-0.0-0.2-0.0-0.00.20.00.00.1-0.1-0.00.1-0.1-0.10.20.10.3
Bone: trabecular number0.00.10.3-0.3-0.2-0.20.1-0.3-0.3-0.2-0.1-0.1-0.2-0.20.10.0-0.10.2-0.1-0.20.10.2-0.4-0.20.5-0.1-0.5
Bone: trabecular spacing1.11.41.81.31.41.4-1.21.31.31.21.31.21.21.21.1-1.31.2-1.21.21.2-1.11.01.21.20.81.20.8
Bone: trabecular thickness1.21.42.4-1.4-1.4-1.51.2-1.3-1.3-1.4-1.1-1.2-1.4-1.2-1.11.2-1.01.3-1.2-1.41.0-1.0-1.6-1.3-0.4-0.7-0.3
Bone: trabecular tissue density0.40.52.5-0.4-0.4-0.40.8-0.3-0.3-0.3-0.9-0.7-0.4-0.6-0.91.0-0.80.5-0.6-0.40.9-1.00.0-0.3-1.5-1.60.3
Water consumed over 24 hours1.11.42.81.31.21.3-1.01.41.41.51.01.21.51.21.1-1.01.0-1.31.31.5-0.91.01.71.70.20.30.0
Number of responses in last shaping day0.20.20.4-0.5-0.6-0.50.4-0.4-0.4-0.6-0.5-0.4-0.5-0.4-0.50.5-0.30.5-0.5-0.60.3-0.4-0.6-0.6-0.5-0.5-0.4