Hub : Genes

Amotl2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Amotl2 0.11 0.06 8.7e-11 0.04 0.1 0.09 0.09 1.4e-04 1.5e-09 5.8e-09 1.4e-08
2 BLA gene expression Amotl2 0.28 0.16 1.2e-11 0.19 0.19 0.22 0.14 1.6e-10 1.5e-10 7.0e-12 4.8e-08
3 NAcc gene expression Amotl2 0.08 0.04 4.0e-13 0.11 0.11 0.1 0.11 1.2e-12 6.6e-13 4.6e-12 9.4e-13
4 LHb gene expression Amotl2 0.36 0.16 3.2e-05 0.2 0.24 0.22 0.18 2.2e-05 2.5e-06 7.1e-06 4.7e-05
5 RMTg gene expression Amotl2 0.16 0.11 5.1e-03 0.09 0.08 0.1 0.11 2.7e-03 3.5e-03 1.6e-03 6.9e-04
6 Brain mRNA stability Amotl2 0.09 0.06 1.4e-05 0.07 0.06 0.05 0.07 2.1e-07 4.5e-06 9.4e-06 2.0e-07
7 Adipose alternative TSS XM_039082102.1 0.1 0.07 6.3e-05 0.04 0.02 0.02 0.03 6.7e-05 1.4e-03 2.3e-03 7.2e-04
8 Adipose alternative TSS XM_006243680.4 0.05 0.04 1.4e-03 0.02 0.01 0.02 0.02 1.0e-03 1.2e-02 3.2e-03 3.9e-03
9 Adipose alternative TSS XM_039082102.1 0.05 0.04 1.9e-03 0.03 0.01 0.02 0.01 6.1e-04 1.9e-02 5.7e-03 8.5e-03
10 Adipose isoform ratio XM_039082102.1 0.08 0.06 2.1e-04 0.03 0.02 0.02 0.02 2.2e-04 6.3e-03 4.9e-03 2.2e-03
11 Adipose mRNA stability Amotl2 0.14 0.07 1.8e-10 0.08 0.07 0.08 0.07 3.2e-09 1.1e-08 6.9e-09 1.7e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.71.11.61.0-1.11.20.30.5-0.3-1.31.3-1.3-1.31.3
Area under the delay curve2.42.54.40.7-0.00.31.71.2-1.02.0-2.12.12.1-2.1
BMI with tail0.62.02.91.3-0.81.11.71.6-1.41.2-1.61.61.6-1.6
BMI without tail2.34.78.32.5-2.02.22.92.8-2.61.6-1.71.71.7-1.7
Body weight2.29.117.23.6-2.93.24.14.0-3.61.8-2.22.22.2-2.2
Weight adjusted by age0.60.71.81.1-1.31.00.91.0-1.20.30.2-0.2-0.20.2
Bone surface1.42.45.0-0.1-0.20.3-1.1-0.71.0-2.22.2-2.2-2.22.2
Bone volume0.91.63.30.4-0.60.7-0.5-0.10.4-1.81.8-1.8-1.81.8
Breakpoint value in progressive ratio session0.40.41.0-0.90.8-1.0-0.6-0.50.60.6-0.30.30.3-0.3
Number of licking bursts0.00.00.10.1-0.20.20.10.2-0.2-0.0-0.00.00.0-0.0
Context. condit. distance diff. score3.23.88.42.9-2.92.82.32.4-2.5-0.40.2-0.2-0.20.2
Locomotion velocity, session 10.60.61.10.7-0.80.80.20.3-0.2-0.61.1-1.1-1.11.1
Locomotion distance, session 11.11.52.61.0-1.11.20.10.4-0.1-1.31.6-1.6-1.61.6
Locomotion velocity, session 20.10.10.20.3-0.30.10.4-0.1-0.40.1-0.30.30.3-0.3
Locomotion distance, session 20.10.10.30.4-0.20.30.50.2-0.10.3-0.20.20.2-0.2
Locomotion velocity, session 30.30.30.60.4-0.50.60.10.5-0.1-0.80.6-0.6-0.60.6
Locomotion distance, session 30.40.51.1-0.20.30.0-0.6-0.20.9-1.10.8-0.8-0.80.8
Stereotopy head waving bouts, day 30.20.30.5-0.70.7-0.7-0.2-0.20.20.7-0.50.50.5-0.5
Stereotopy head waving duration, day 30.10.10.5-0.20.4-0.30.10.2-0.00.7-0.40.40.4-0.4
Locomotion velocity, session 70.60.71.00.9-1.01.00.40.6-0.4-0.80.9-0.9-0.90.9
Locomotion distance, session 70.00.00.0-0.00.0-0.10.10.00.00.2-0.20.20.2-0.2
Stereotopy head waving bouts, day 70.91.02.10.1-0.10.4-0.60.10.5-1.41.5-1.5-1.51.5
Stereotopy head waving duration, day 70.50.71.40.3-0.30.6-0.20.30.1-1.01.2-1.2-1.21.2
Locomotion velocity, session 81.92.35.32.1-2.32.21.61.8-1.9-0.60.5-0.5-0.50.5
Locomotion distance, session 82.74.09.13.0-3.02.92.32.4-2.3-0.60.4-0.4-0.40.4
Degree of sensitization distance0.60.61.60.2-0.4-0.00.70.3-0.91.3-0.90.90.9-0.9
Degree of sensitization stereotypy1.41.62.90.7-0.81.1-0.10.50.1-1.71.7-1.7-1.71.7
Conditioned locomotion0.50.61.2-0.3-0.2-0.0-0.8-0.50.4-0.91.1-1.1-1.11.1
Cocaine response after cond. corrected1.01.12.3-0.30.5-0.60.50.1-0.41.5-1.51.51.5-1.5
Cocaine response after cond. not corrected1.01.02.10.00.3-0.30.80.3-0.61.3-1.51.51.5-1.5
Cocaine response before conditioning0.30.30.70.7-0.80.80.50.4-0.6-0.40.4-0.4-0.40.4
Saline control response0.91.12.61.5-1.41.61.21.4-1.2-0.40.4-0.4-0.40.4
Bone: connectivity density0.10.20.30.5-0.50.50.20.4-0.2-0.50.4-0.4-0.40.4
Bone: cortical apparent density1.21.62.7-0.80.5-0.4-1.4-1.01.3-1.61.5-1.5-1.51.5
Bone: cortical area1.52.23.81.6-1.81.90.61.2-0.7-1.51.6-1.6-1.61.6
Bone: cortical porosity1.71.84.40.1-0.40.6-0.8-0.40.6-2.11.9-1.9-1.91.9
Bone: cortical porosity1.71.94.50.1-0.40.6-0.9-0.40.7-2.11.9-1.9-1.91.9
Bone: cortical thickness0.61.02.31.4-1.41.50.91.3-0.9-0.50.6-0.6-0.60.6
Bone: cortical thickness0.20.30.40.5-0.60.60.00.3-0.1-0.40.6-0.6-0.60.6
Bone: cortical tissue density1.21.62.6-0.80.6-0.5-1.5-1.01.3-1.61.5-1.5-1.51.5
Condit. Reinf. active minus inactive responses0.40.50.80.4-0.10.20.80.6-0.70.6-0.90.90.9-0.9
Condit. Reinf. active-inactive response ratio1.21.32.91.7-1.61.71.31.5-1.4-0.60.1-0.1-0.10.1
Condit. Reinf. active responses1.01.32.6-0.50.7-0.80.40.1-0.21.4-1.61.61.6-1.6
Condit. Reinf. inactive responses1.21.42.6-1.41.5-1.6-0.5-0.80.71.4-1.11.11.1-1.1
Incentive salience index mean0.60.71.4-0.50.8-0.70.20.10.00.8-1.21.21.2-1.2
Condit. Reinf. lever presses1.11.42.2-1.11.4-1.3-0.2-0.30.61.2-1.51.51.5-1.5
Condit. Reinf. active minus inactive responses2.12.66.2-1.82.5-2.1-0.7-1.11.51.3-1.51.51.5-1.5
Condit. Reinf. active-inactive response ratio2.32.44.9-0.21.0-0.81.00.4-0.22.0-2.22.22.2-2.2
Condit. Reinf. active responses2.43.37.6-2.22.8-2.5-1.1-1.61.81.4-1.51.51.5-1.5
Condit. Reinf. inactive responses2.73.36.4-2.52.3-2.3-2.5-2.52.4-0.60.6-0.6-0.60.6
Condit. Reinf. lever presses1.62.14.6-1.82.1-2.1-1.0-1.41.30.9-1.21.21.2-1.2
Condit. Reinf. lever reinforcers received2.73.98.6-2.42.9-2.7-1.2-1.71.81.6-1.61.61.6-1.6
Conditioned reinforcement - actives2.12.14.11.9-1.91.81.81.8-2.00.6-0.70.70.7-0.7
Conditioned reinforcement - inactives0.50.61.41.2-1.01.11.00.9-1.10.1-0.10.10.1-0.1
Conditioned locomotion0.40.51.70.8-1.30.90.30.6-0.8-0.10.6-0.6-0.60.6
Patch foraging indifference point 0 sec0.40.60.90.8-0.80.90.30.6-0.3-0.80.9-0.9-0.90.9
Patch foraging indifference point AUC0.80.91.8-1.01.3-1.2-0.3-0.80.61.1-0.90.90.9-0.9
Delay disc. indifference point, 0s delay0.50.61.00.5-0.00.31.01.0-0.41.0-0.80.80.8-0.8
Delay disc. indifference point, 16s delay1.71.72.61.0-0.50.61.61.2-1.21.2-1.61.61.6-1.6
Delay disc. indifference point, 2s delay0.91.02.30.9-0.40.61.51.1-0.81.1-1.01.01.0-1.0
Delay disc. indifference point, 24s delay2.62.54.90.30.2-0.31.30.7-0.92.1-2.22.22.2-2.2
Delay disc. indifference point, 4s delay1.41.52.70.50.10.11.30.8-0.71.6-1.61.61.6-1.6
Delay disc. indifference point, 8s delay1.31.32.40.40.20.11.20.9-0.61.5-1.51.51.5-1.5
Indifference point function ln k0.50.72.50.3-0.50.6-0.30.00.1-1.61.1-1.1-1.11.1
Indifference point function log k0.50.72.50.3-0.50.6-0.30.00.1-1.61.1-1.1-1.11.1
Patch foraging total patch changes 0 sec0.20.40.80.3-0.30.5-0.10.20.1-0.70.9-0.9-0.90.9
Patch foraging total patch changes 12 sec0.20.30.7-0.70.8-0.7-0.6-0.60.60.10.0-0.0-0.00.0
Patch foraging total patch changes 18 sec0.30.40.80.9-0.80.90.70.9-0.70.30.1-0.1-0.10.1
Patch foraging total patch changes 24 sec0.00.00.00.00.10.00.1-0.0-0.0-0.0-0.00.00.0-0.0
Patch foraging total patch changes 6 sec0.40.61.3-0.30.3-0.0-0.7-0.40.7-0.81.1-1.1-1.11.1
Patch foraging time to switch 0 sec0.30.50.80.4-0.80.6-0.10.3-0.3-0.80.9-0.9-0.90.9
Patch foraging water rate 0 sec1.32.04.00.30.3-0.21.20.7-0.61.9-2.02.02.0-2.0
Patch foraging water rate 12 sec1.32.04.11.4-0.91.02.01.5-1.41.5-1.41.41.4-1.4
Patch foraging water rate 18 sec1.01.42.71.4-1.11.21.61.6-1.30.7-0.90.90.9-0.9
Patch foraging water rate 24 sec1.11.52.21.1-1.01.01.51.5-1.41.3-1.21.21.2-1.2
Patch foraging water rate 6 sec1.42.13.41.2-0.70.71.91.3-1.41.5-1.71.71.7-1.7
Seeking ratio, delayed vs. immediate footshock1.51.73.4-0.3-0.00.1-1.2-0.50.9-1.51.8-1.8-1.81.8
Distance traveled before self-admin1.92.05.41.8-1.41.71.92.3-1.61.2-0.50.50.5-0.5
Distance traveled after self-admin0.50.51.40.9-1.20.90.60.5-1.1-0.10.5-0.5-0.50.5
Extensor digitorum longus weight0.83.26.30.40.2-0.21.50.9-1.02.5-2.52.52.5-2.5
Bone: elastic displacement1.11.22.71.6-1.61.51.31.3-1.50.20.1-0.1-0.10.1
Bone: elastic work2.83.78.02.6-2.82.81.72.1-1.9-0.81.2-1.2-1.21.2
Bone: endosteal estimation0.91.93.41.0-1.11.3-0.00.50.1-1.81.9-1.9-1.91.9
Bone: endosteal perimeter0.20.50.9-0.1-0.10.2-0.5-0.30.4-0.91.0-1.0-1.01.0
Epididymis fat weight0.30.71.90.7-0.10.61.11.4-0.31.0-0.80.80.8-0.8
Delta time in closed arm before/after self-admin0.40.41.10.9-0.71.10.70.8-0.4-0.30.3-0.3-0.30.3
Delta time in open arm before/after self-admin0.50.51.1-0.81.0-0.6-0.9-0.51.0-0.10.5-0.5-0.50.5
Diff in mean of infusions in LGA sessions0.20.20.7-0.70.8-0.6-0.6-0.10.70.2-0.30.30.3-0.3
Delay discount exponential model param2.62.74.7-0.80.1-0.3-1.9-1.31.1-2.12.2-2.2-2.22.2
Extinction: sum of active levers before priming0.10.10.10.10.10.2-0.10.30.3-0.40.3-0.3-0.30.3
Active lever presses in extinction session 60.60.61.00.20.20.10.50.8-0.40.9-1.01.01.0-1.0
Bone: final force0.50.81.71.2-1.11.30.81.0-0.6-0.70.7-0.7-0.70.7
Bone: final moment0.71.12.51.4-1.31.60.91.2-0.8-0.90.8-0.8-0.80.8
Food consumed during 24 hour testing period0.70.82.11.4-1.21.51.01.1-0.8-0.50.4-0.4-0.40.4
Glucose3.24.88.72.4-1.91.92.92.6-2.71.6-1.91.91.9-1.9
Heart weight0.50.71.50.8-0.30.81.11.2-0.60.8-0.80.80.8-0.8
Delay discount hyperbolic model param2.32.44.1-0.80.1-0.3-1.8-1.11.0-2.02.0-2.0-2.02.0
Intermittent access intake day 1-15 change2.32.34.00.7-0.20.31.50.8-1.42.0-2.02.02.0-2.0
Intermittent access intake escalation2.42.33.61.0-0.60.71.61.2-1.51.8-1.91.91.9-1.9
Intermittent access intake escalation 20.50.50.70.5-0.40.30.80.3-0.80.7-0.80.80.8-0.8
Intermitt. access day 1 inactive lever presses0.50.50.7-0.70.9-0.7-0.4-0.50.30.4-0.80.80.8-0.8
Intermitt. access day 15 inactive lever presses0.50.51.3-0.70.4-0.5-1.1-0.90.6-0.70.7-0.7-0.70.7
Intermitt. access escalation Index0.20.20.8-0.20.6-0.1-0.20.30.90.30.4-0.4-0.40.4
Intermittent access day 1 total infusions0.81.02.51.2-1.61.21.01.2-1.40.6-0.40.40.4-0.4
Intermittent access day 15 total infusions2.93.34.21.4-1.41.11.91.6-2.12.0-2.02.02.0-2.0
Intermittent access terminal intake (last 3 days)3.94.37.82.2-2.31.92.52.1-2.81.7-1.71.71.7-1.7
Intermittent access total infusions2.62.95.01.9-2.01.71.92.0-2.21.4-1.31.31.3-1.3
Intermittent access day 1 locomotion0.50.51.10.4-0.80.30.50.4-0.81.0-0.80.80.8-0.8
Intermittent access day 15 total locomotion2.42.54.91.9-2.01.81.72.1-2.20.9-1.01.01.0-1.0
Intermittent access total locomotion2.12.43.91.5-1.71.41.61.8-2.01.5-1.31.31.3-1.3
Intermittent access standard deviation0.30.30.6-0.1-0.3-0.40.2-0.6-0.80.7-0.60.60.6-0.6
Left kidney weight0.61.83.51.6-1.31.90.91.1-0.5-1.41.4-1.4-1.41.4
Right kidney weight0.30.82.01.4-1.11.41.00.9-0.6-0.50.6-0.6-0.60.6
Cocaine induced anxiety0.10.10.60.5-0.50.50.20.2-0.3-0.80.1-0.1-0.10.1
Post-drug Anxiety0.10.10.30.4-0.50.40.40.1-0.5-0.4-0.20.20.2-0.2
Baseline Anxiety0.20.20.4-0.10.3-0.10.20.2-0.20.6-0.60.60.6-0.6
Tail length2.47.113.53.4-3.03.03.73.6-3.41.8-1.41.41.4-1.4
Length with tail2.07.514.53.7-3.33.43.83.7-3.51.1-1.11.11.1-1.1
Length without tail0.51.12.21.5-1.21.31.51.4-1.2-0.1-0.40.40.4-0.4
Times rat made contact with spout0.30.30.70.5-0.60.60.10.1-0.1-0.80.7-0.7-0.70.7
Lifetime Intake2.22.54.21.8-1.81.61.81.8-2.01.4-1.21.21.2-1.2
Liver weight, left0.00.00.1-0.10.3-0.1-0.10.30.30.10.1-0.1-0.10.1
Liver weight, right0.30.50.80.8-0.70.60.90.8-0.70.6-0.60.60.6-0.6
Locomotor activity0.50.81.71.3-1.11.21.30.9-1.3-0.1-0.30.30.3-0.3
Locomotor testing distance0.71.22.51.6-1.41.61.31.1-1.6-0.60.1-0.1-0.10.1
Locomotor testing rearing0.40.51.3-0.81.2-1.0-0.3-0.80.60.3-0.70.70.7-0.7
Locomotion in novel chamber1.21.53.9-1.71.4-1.8-1.7-2.01.3-0.30.1-0.1-0.10.1
Locomotion in novel chamber post-restriction0.70.81.60.3-0.1-0.00.70.3-0.71.0-1.31.31.3-1.3
Fecal boli incidents, locomotor time 11.41.63.2-0.00.3-0.51.00.2-0.51.7-1.81.81.8-1.8
Change in fecal boli incidents, locomotor task2.52.45.10.6-1.11.1-0.50.0-0.1-2.32.1-2.1-2.12.1
Time >=10cm from walls, locomotor time 10.80.81.7-0.91.1-0.8-1.0-1.11.3-0.70.7-0.7-0.70.7
Bouts of movement, locomotor time 10.20.30.6-0.70.6-0.7-0.7-0.70.5-0.30.2-0.2-0.20.2
Total resting periods, locomotor time 10.30.30.6-0.80.8-0.8-0.7-0.70.6-0.10.1-0.1-0.10.1
Rest time, locomotor task time 10.10.10.3-0.40.4-0.5-0.2-0.30.40.3-0.40.40.4-0.4
Distance moved, locomotor task time 10.40.51.00.9-0.91.00.61.0-0.9-0.10.3-0.3-0.30.3
Vertical activity count, locomotor time 10.00.00.1-0.20.3-0.2-0.3-0.00.1-0.10.2-0.2-0.20.2
Time >=10cm from walls, locomotor time 20.80.81.6-0.61.0-0.90.2-0.20.41.3-1.11.11.1-1.1
Bouts of movement, locomotor time 21.01.02.2-0.91.0-1.1-0.3-0.50.31.5-1.21.21.2-1.2
Total resting periods, locomotor time 20.91.02.0-0.91.0-1.1-0.4-0.60.41.4-1.11.11.1-1.1
Rest time, locomotor task time 20.10.10.5-0.40.2-0.4-0.2-0.70.30.1-0.10.10.1-0.1
Distance moved, locomotor task time 20.70.81.30.6-0.70.9-0.00.7-0.3-1.01.1-1.1-1.11.1
Vertical activity count, locomotor time 21.71.93.2-1.41.3-1.1-1.8-1.11.7-1.31.3-1.3-1.31.3
Light reinforcement 12.13.86.50.9-0.80.41.91.5-2.12.1-2.52.52.5-2.5
Light reinforcement 21.92.55.22.0-2.01.82.12.0-2.30.5-0.80.80.8-0.8
Bone: marrow area0.92.03.51.0-1.11.40.00.50.0-1.81.9-1.9-1.91.9
Bone: maximum diameter0.81.42.21.1-1.21.30.20.7-0.2-1.41.5-1.5-1.51.5
Bone: maximum force1.73.04.81.8-2.02.20.71.1-0.7-1.91.9-1.9-1.91.9
Bone: maximum moment2.03.55.92.0-2.22.40.81.3-0.9-2.12.0-2.0-2.02.0
Mean time between licks in bursts0.30.40.9-0.91.0-0.9-0.5-0.60.70.4-0.30.30.3-0.3
Mean num. licks in bursts0.20.30.50.4-0.40.50.10.0-0.1-0.70.7-0.7-0.70.7
Cd content in liver2.02.24.61.9-1.81.72.01.8-2.11.0-0.70.70.7-0.7
Co content in liver0.00.00.20.1-0.30.20.10.4-0.30.30.0-0.0-0.00.0
Cu content in liver1.11.32.60.5-0.71.1-0.40.70.2-1.61.5-1.5-1.51.5
Fe content in liver0.70.82.11.3-1.11.31.11.4-1.1-0.00.1-0.1-0.10.1
K content in liver2.72.66.1-0.91.4-1.40.3-0.10.22.5-2.12.12.1-2.1
Mg content in liver1.51.53.7-0.81.2-1.20.2-0.20.41.9-1.51.51.5-1.5
Mn content in liver0.10.10.4-0.50.6-0.5-0.3-0.30.50.40.0-0.0-0.00.0
Na content in liver0.10.10.50.3-0.10.40.30.7-0.1-0.00.2-0.2-0.20.2
Rb content in liver2.12.65.90.30.2-0.21.41.2-0.92.4-2.12.12.1-2.1
Se content in liver0.00.10.20.2-0.30.30.10.3-0.4-0.00.2-0.2-0.20.2
Sr content in liver0.20.20.4-0.10.0-0.20.10.1-0.30.6-0.60.60.6-0.6
Zn content in liver1.31.53.8-0.20.5-0.50.60.5-0.51.9-1.71.71.7-1.7
Bone: minimum diameter0.91.72.90.9-1.21.3-0.10.5-0.1-1.71.7-1.7-1.71.7
Time in familiar zone, hab. session 13.33.14.4-1.10.7-0.6-2.0-1.71.9-2.02.1-2.1-2.12.1
Time in novel zone, hab. session 13.53.46.41.8-1.61.52.52.3-2.51.8-1.51.51.5-1.5
Total zone transitions, hab. session 10.91.32.70.7-0.30.21.30.9-0.91.6-1.41.41.4-1.4
Total locomotion distance, hab. session 10.10.10.4-0.50.4-0.6-0.3-0.50.40.3-0.10.10.1-0.1
Locomotion velocity, hab. session 10.10.10.3-0.40.5-0.6-0.3-0.40.50.4-0.20.20.2-0.2
Time in familiar zone, hab. session 20.70.72.1-0.90.7-0.9-1.0-1.40.9-0.20.6-0.6-0.60.6
Time in novel zone, hab. session 21.31.33.31.5-1.51.71.21.8-1.3-0.50.0-0.0-0.00.0
Total zone transitions, hab. session 20.10.20.80.00.1-0.30.3-0.1-0.00.9-0.40.40.4-0.4
Total locomotion distance, hab. session 20.60.82.1-1.01.0-1.1-1.0-1.51.2-0.00.4-0.4-0.40.4
Locomotion velocity, hab. session 20.91.32.9-1.31.2-1.3-1.4-1.71.6-0.30.7-0.7-0.70.7
Novel to familiar place preference ratio0.70.71.40.7-0.71.00.10.9-0.1-1.20.9-0.9-0.90.9
Novelty place preference1.01.01.90.9-1.01.30.21.0-0.2-1.41.1-1.1-1.11.1
Time in novel zone, NPP test0.70.81.50.9-1.01.20.31.0-0.4-1.10.8-0.8-0.80.8
Total zone transitions, NPP test0.30.41.40.20.0-0.10.60.1-0.31.2-0.70.70.7-0.7
Total locomotion distance, NPP test0.60.81.8-0.80.9-1.1-0.2-0.60.41.3-1.01.01.0-1.0
Locomotion velocity, NPP test0.40.61.2-0.81.0-1.1-0.3-0.70.61.1-0.70.70.7-0.7
Intraocular pressure0.60.91.80.6-0.50.8-0.1-0.00.3-1.31.3-1.3-1.31.3
Delta distance traveled before/after self-admin0.50.61.50.1-0.50.3-0.5-0.50.0-1.21.0-1.0-1.01.0
Delta ambulatory time before/after self-admin0.30.40.90.2-0.70.4-0.3-0.4-0.3-1.00.7-0.7-0.70.7
Parametrial fat weight1.32.65.01.9-1.61.62.22.0-2.01.1-1.21.21.2-1.2
Pavlov. Cond. lever latency1.21.63.41.7-1.41.51.71.8-1.60.7-0.50.50.5-0.5
Pavlov. Cond. magazine entry latency1.52.03.4-1.21.0-0.9-1.8-1.81.7-1.61.2-1.2-1.21.2
Pavlov. Cond. change in total contacts1.41.53.8-1.61.5-1.5-1.6-1.91.6-0.50.3-0.3-0.30.3
Pavlov. Cond. index score1.82.24.4-1.71.4-1.4-2.0-2.11.9-1.31.0-1.0-1.01.0
Pavlov. Cond. latency score1.41.73.1-1.41.1-1.1-1.8-1.81.7-1.31.0-1.0-1.01.0
Pavlov. Cond. lever contacts0.81.01.9-1.10.9-0.9-1.4-1.41.2-1.10.7-0.7-0.70.7
Pavlov. Cond. magazine entry number2.22.75.31.8-1.61.52.22.3-2.21.4-1.01.01.0-1.0
Pavlov. Cond. intertrial magazine entries0.10.10.20.1-0.10.3-0.10.30.0-0.50.4-0.4-0.40.4
Pavlov. Cond. lever-magazine prob. diff.2.12.65.6-2.01.7-1.7-2.2-2.42.1-1.20.8-0.8-0.80.8
Pavlov. Cond. response bias1.31.63.4-1.51.3-1.3-1.7-1.91.6-1.00.7-0.7-0.70.7
Pavlov. Cond. lever latency2.53.47.22.4-2.72.71.41.9-1.7-1.41.4-1.4-1.41.4
Pavlov. Cond. magazine entry latency1.41.63.3-1.81.7-1.8-1.5-1.81.60.0-0.10.10.1-0.1
Pavlov. Cond. change in total contacts2.43.26.1-2.12.4-2.5-1.0-1.61.31.5-1.81.81.8-1.8
Pavlov. Cond. index score2.22.86.3-2.32.5-2.5-1.6-2.01.80.8-0.90.90.9-0.9
Pavlov. Cond. latency score2.12.65.8-2.32.3-2.4-1.7-2.01.80.6-0.50.50.5-0.5
Pavlov. Cond. lever contacts2.02.76.1-2.22.5-2.4-1.4-1.81.70.9-1.11.11.1-1.1
Pavlov. Cond. magazine entry number2.93.67.72.7-2.72.82.12.5-2.3-0.40.5-0.5-0.50.5
Pavlov. Cond. intertrial magazine entries0.60.82.0-1.21.4-1.2-0.8-0.81.00.4-0.40.40.4-0.4
Pavlov. Cond. lever-magazine prob. diff.2.53.27.0-2.42.6-2.6-1.6-2.11.81.0-1.01.01.0-1.0
Pavlov. Cond. response bias3.44.69.4-2.73.1-3.1-1.6-2.22.01.4-1.61.61.6-1.6
Time in closed arm before self-admin0.20.30.6-0.70.7-0.7-0.5-0.80.40.3-0.30.30.3-0.3
Time in closed arm after self-admin0.20.30.50.2-0.00.10.50.3-0.30.5-0.70.70.7-0.7
Time in open arm before self-admin0.50.51.10.7-1.00.80.40.4-0.7-1.00.7-0.7-0.70.7
Time in open arm after self-admin1.61.82.6-0.90.9-0.5-1.4-1.01.4-1.51.6-1.6-1.61.6
Bone: periosteal estimation1.83.85.41.8-2.12.30.51.3-0.6-2.22.3-2.3-2.32.3
Bone: periosteal perimeter0.61.12.10.5-0.70.8-0.30.20.2-1.41.4-1.4-1.41.4
Bone: post-yield work0.30.40.80.2-0.1-0.00.60.2-0.60.6-0.90.90.9-0.9
Progressive ratio test 1 active lever presses0.60.71.91.1-1.41.20.61.0-1.10.20.2-0.2-0.20.2
Progressive ratio test 1 breakpoint0.70.71.91.1-1.41.10.81.1-1.20.5-0.00.00.0-0.0
Progressive ratio test 1 inactive lever presses0.10.10.30.2-0.30.20.10.3-0.50.6-0.40.40.4-0.4
Progressive ratio test 2 active lever presses2.62.85.12.2-2.22.02.02.0-2.20.6-1.01.01.0-1.0
Progressive ratio test 2 breakpoint2.02.24.01.9-1.91.71.81.7-2.00.7-1.01.01.0-1.0
Progressive ratio test 2 inactive lever presses0.91.01.50.9-0.90.61.10.7-1.20.8-1.11.11.1-1.1
Incentive Sensitization - Responses1.81.84.42.0-2.11.81.61.5-1.90.0-0.40.40.4-0.4
Incentive Sensitization - Breakpoint1.61.63.91.8-2.01.71.51.4-1.7-0.0-0.30.30.3-0.3
Sum of active levers in priming session hrs 5-60.10.10.20.2-0.40.20.20.4-0.40.40.1-0.1-0.10.1
Progressive ratio1.92.24.9-2.11.8-2.2-1.7-2.11.50.9-0.50.50.5-0.5
Food seeking constrained by brief footshock1.11.43.41.6-1.91.71.01.4-1.4-0.50.6-0.6-0.60.6
Seeking ratio, punishment vs. effort2.83.57.62.6-2.52.81.92.5-1.9-1.10.7-0.7-0.70.7
Retroperitoneal fat weight1.85.910.51.0-0.30.22.41.7-1.73.2-3.23.23.2-3.2
Reaction time number correct0.30.41.00.7-0.50.61.00.7-0.70.3-0.50.50.5-0.5
Reaction time mean minus median1.01.32.2-0.91.4-1.1-0.2-0.20.70.8-1.51.51.5-1.5
Reaction time mean minus median AUC1.41.94.0-0.51.1-0.80.40.40.11.5-2.02.02.0-2.0
Reaction time num false alarms0.30.40.9-0.90.9-1.0-0.7-0.80.6-0.1-0.10.10.1-0.1
Reaction time num false alarms AUC0.10.10.3-0.50.4-0.5-0.5-0.60.3-0.20.1-0.1-0.10.1
Reaction time trials correct on left0.30.41.00.7-0.50.61.00.7-0.70.3-0.50.50.5-0.5
Reaction time trials on left0.30.41.00.7-0.40.51.00.7-0.70.4-0.60.60.6-0.6
Reaction time mean0.81.12.6-1.51.6-1.4-1.2-1.11.30.1-0.50.50.5-0.5
Reaction time mean AUC0.81.02.5-1.41.6-1.3-1.2-1.01.4-0.0-0.30.30.3-0.3
Median of all reaction times0.71.01.9-1.41.3-1.2-1.3-1.31.4-0.30.1-0.1-0.10.1
Reaction time omissions1.52.03.5-1.11.6-1.4-0.1-0.50.51.3-1.91.91.9-1.9
Reaction time false alarm rate0.20.30.6-0.70.5-0.7-0.8-0.70.5-0.30.3-0.3-0.30.3
Reaction time premature initiation rate3.95.37.31.6-1.41.02.61.8-2.72.5-2.72.72.7-2.7
Reaction time premature initiations3.85.47.61.7-1.31.02.71.8-2.62.4-2.72.72.7-2.7
Std. dev. reaction times1.01.43.3-1.41.8-1.5-0.8-0.81.30.6-1.11.11.1-1.1
Reaction time trials completed0.30.41.00.7-0.40.51.00.7-0.70.4-0.60.60.6-0.6
Reaction time trials AUC0.30.51.20.8-0.50.61.10.8-0.80.3-0.60.60.6-0.6
Run reversals in cocaine runway, females1.31.32.5-1.61.5-1.4-1.6-1.51.4-0.40.3-0.3-0.30.3
Run reversals in cocaine runway, males1.41.43.21.8-1.81.71.40.9-1.4-0.70.4-0.4-0.40.4
Latency to leave start box in cocaine runway5.15.510.7-3.02.8-2.5-3.3-2.83.0-1.61.3-1.3-1.31.3
Latency to leave start box in cocaine runway, F2.02.25.2-2.22.3-2.0-2.0-1.62.0-0.40.1-0.1-0.10.1
Latency to leave start box in cocaine runway, M2.62.44.7-1.71.2-1.4-2.2-2.11.7-1.31.3-1.3-1.31.3
Std. dev. time between licks in bursts2.63.17.1-2.52.5-2.7-1.7-2.21.80.9-0.80.80.8-0.8
Total sessions with >9 infusions0.20.30.60.2-0.40.20.30.4-0.50.8-0.60.60.6-0.6
Short access day 1 total inactive lever presses0.20.20.40.4-0.40.50.00.00.1-0.40.6-0.6-0.60.6
Short access day 10 total inactive lever presses0.60.71.6-1.11.2-1.2-0.8-1.11.10.4-0.20.20.2-0.2
Short access day 1 total infusions0.40.51.31.0-1.11.00.70.7-0.5-0.10.4-0.4-0.40.4
Short access day 10 total infusions2.22.44.31.7-1.91.51.71.7-2.11.6-1.11.11.1-1.1
Short access total infusions1.01.11.51.1-1.11.01.21.2-1.21.2-0.80.80.8-0.8
Short access day 1 locomotion1.31.43.11.6-1.61.41.61.8-1.30.4-0.40.40.4-0.4
Short access day 10 total locomotion0.80.92.9-0.0-0.3-0.30.40.1-0.51.7-1.31.31.3-1.3
Short access total locomotion1.11.21.51.0-1.10.81.21.2-1.21.2-1.01.01.0-1.0
One hour access (0.3 mA shock)2.73.14.41.6-1.41.32.11.8-2.01.9-1.81.81.8-1.8
Compulsive drug intake1.01.02.4-1.31.1-1.3-1.1-1.51.3-0.20.4-0.4-0.40.4
One hour access (shock baseline)4.55.28.12.5-2.42.32.72.8-2.81.9-1.81.81.8-1.8
Social response proportion0.10.20.4-0.50.6-0.6-0.5-0.40.40.30.1-0.1-0.10.1
Social responses1.62.05.3-0.10.4-0.61.00.3-0.62.3-1.91.91.9-1.9
Social time2.53.37.2-2.62.7-2.6-2.1-2.32.30.2-0.20.20.2-0.2
Soleus weight5.415.730.04.9-4.34.35.55.1-5.12.6-2.42.42.4-2.4
Bone: stiffness0.81.23.10.2-0.30.5-0.5-0.40.6-1.81.5-1.5-1.51.5
Tibialis anterior weight0.10.20.5-0.20.2-0.30.1-0.2-0.10.3-0.70.70.7-0.7
Time to tail flick, vehicle, before self-admin0.90.91.90.4-0.20.10.90.5-0.61.1-1.41.41.4-1.4
Time to tail flick, vehicle, after self-admin0.40.40.8-0.80.8-0.7-0.9-0.60.90.10.5-0.5-0.50.5
Time to tail flick, test, before self-admin0.80.71.41.2-0.91.11.21.2-1.00.3-0.50.50.5-0.5
Time to tail flick, test, after self-admin0.70.71.71.1-1.11.30.91.3-1.0-0.00.1-0.1-0.10.1
Delta time to tail flick, vehicle, before/after SA2.12.13.3-1.21.1-0.7-1.8-1.01.6-0.91.7-1.7-1.71.7
Delta time to tail flick, test, before/after SA0.10.10.50.3-0.20.50.10.7-0.1-0.10.2-0.2-0.20.2
Tibia length0.92.75.01.4-1.41.80.30.9-0.2-2.22.0-2.0-2.02.0
Ambulatory time before self-admin2.72.86.31.8-1.41.52.12.5-2.11.6-1.21.21.2-1.2
Ambulatory time after self-admin0.60.72.01.0-1.20.90.90.9-1.40.7-0.20.20.2-0.2
Bone: tissue strength4.74.69.12.6-2.22.23.02.6-2.81.2-1.51.51.5-1.5
Total heroin consumption0.40.51.50.8-1.20.90.30.7-0.7-0.60.5-0.5-0.50.5
Bone: trabecular number0.10.20.40.2-0.20.3-0.1-0.10.1-0.60.7-0.7-0.70.7
Bone: trabecular spacing1.52.03.8-0.81.2-1.20.2-0.10.01.8-1.91.91.9-1.9
Bone: trabecular thickness2.22.75.22.0-2.22.31.01.5-1.2-1.51.5-1.5-1.51.5
Bone: trabecular tissue density0.40.61.00.8-1.01.00.20.4-0.4-0.80.9-0.9-0.90.9
Water consumed over 24 hours0.91.02.10.3-0.60.5-0.5-0.20.3-1.41.4-1.4-1.41.4
Number of responses in last shaping day0.00.00.10.1-0.10.10.00.10.2-0.40.2-0.2-0.20.2