Hub : Genes

Amigo2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc intron excision ratio chr7_130273092_130273443 0.01 0.01 5.1e-03 0.01 0.01 0.01 -0 1.4e-02 5.0e-03 1.7e-02 5.1e-01
2 NAcc isoform ratio XM_063263370.1 0.01 0.01 4.3e-03 0.01 0.01 0.01 0.01 2.7e-02 2.2e-03 7.5e-03 7.0e-03
3 BLA gene expression Amigo2 0.04 0.03 6.0e-03 0.03 0.04 0.02 0.03 1.5e-02 3.1e-03 4.4e-02 7.7e-03
4 Brain gene expression Amigo2 0.07 0.04 9.1e-10 0.09 0.11 0.1 0.1 1.7e-08 4.0e-10 7.7e-10 1.9e-09
5 pVTA alternative TSS XM_063263370.1 0.03 0.03 2.3e-03 0.02 0.03 0.02 0.02 1.5e-02 1.2e-03 1.4e-02 1.2e-02
6 NAcc isoform ratio NM_182816.3 0.03 0.02 1.2e-05 0.03 0.03 0.03 0.03 8.7e-05 7.9e-06 1.7e-05 8.9e-05
7 IL gene expression Amigo2 0.09 0.07 8.2e-03 0.04 0.08 0.06 0.07 3.5e-02 6.8e-03 1.2e-02 7.5e-03
8 PL gene expression Amigo2 0.05 0.06 9.7e-04 0.02 0.01 0.01 0.01 6.7e-03 1.1e-02 6.9e-02 2.3e-02
9 pVTA gene expression Amigo2 0.11 0.06 3.6e-11 0.13 0.12 0.13 0.13 7.7e-11 1.2e-09 1.2e-10 1.6e-10
10 IC isoform ratio XM_063263369.1 0.06 0.05 7.0e-03 0.02 0.04 0.02 0.01 4.8e-02 7.1e-03 6.1e-02 9.1e-02
11 Liver gene expression Amigo2 0.22 0.11 0.0e+00 0.27 0.26 0.27 0.27 5.1e-30 3.2e-28 7.7e-30 6.4e-30
12 pVTA intron excision ratio chr7_130273092_130273443 0.06 0.04 4.8e-06 0.02 0.07 0.05 0.05 7.2e-03 5.5e-06 4.0e-05 9.1e-05
13 Eye isoform ratio NM_182816.3 0.2 0.15 5.6e-03 0.1 0.06 0.03 0.07 1.4e-02 4.4e-02 1.1e-01 3.0e-02
14 Adipose gene expression Amigo2 0.15 0.08 0.0e+00 0.14 0.15 0.16 0.15 3.6e-15 1.0e-16 3.3e-17 8.5e-17
15 LHb intron excision ratio chr7_130273092_130273443 0.5 0.26 7.5e-03 0.09 0.03 0.07 0.08 3.7e-03 7.1e-02 8.3e-03 5.4e-03
16 IC isoform ratio NM_182816.3 0.07 0.05 6.1e-03 0.05 0.05 0.05 0.06 3.6e-03 4.4e-03 3.2e-03 2.5e-03
17 Liver intron excision ratio chr7_130273092_130273443 0.14 0.11 1.9e-04 0.03 0.02 0.03 0.03 1.9e-04 1.7e-03 8.0e-04 2.5e-04
18 IC gene expression Amigo2 0.42 0.17 3.4e-04 0.05 0.1 0.07 0.06 4.0e-03 4.3e-05 5.6e-04 1.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density6.611.313.03.53.53.53.6-3.5-3.43.53.3-3.33.53.33.4-3.33.23.3-3.32.93.3
Area under the delay curve0.60.71.31.11.01.01.1-0.9-0.80.90.8-0.80.81.10.7-0.40.60.6-0.50.31.0
BMI with tail4.716.323.24.64.54.54.5-4.1-4.14.24.8-4.63.94.23.7-3.23.43.3-3.12.94.0
BMI without tail1.33.96.52.42.32.32.4-2.0-2.02.12.6-2.51.92.01.8-1.11.50.9-1.41.32.2
Body weight4.419.327.35.25.15.05.0-4.7-4.74.75.2-5.04.44.64.1-3.53.53.0-3.43.03.7
Weight adjusted by age0.71.12.41.61.51.41.4-1.3-1.21.11.2-1.21.10.90.8-0.40.30.2-0.40.10.1
Bone surface8.114.716.94.14.14.04.1-3.9-3.94.04.0-4.03.84.03.7-3.93.93.9-3.23.23.4
Bone volume5.49.611.23.33.33.33.3-3.2-3.23.23.2-3.23.13.23.0-3.13.13.1-2.62.62.8
Breakpoint value in progressive ratio session2.53.05.11.41.51.61.6-1.7-1.71.71.6-1.61.91.62.0-1.71.71.7-2.12.31.9
Number of licking bursts0.20.31.2-0.5-0.5-0.5-0.60.30.4-0.4-0.60.6-0.4-0.6-0.40.7-0.5-0.7-0.1-0.4-1.1
Context. condit. distance diff. score0.50.61.70.80.80.80.7-0.7-0.70.70.8-0.80.70.80.7-0.80.80.9-0.31.30.6
Locomotion velocity, session 11.01.11.9-0.8-0.8-0.8-0.90.80.9-0.9-1.21.2-0.9-1.2-0.91.3-1.2-1.30.8-1.4-1.3
Locomotion distance, session 12.73.44.9-1.9-1.9-1.9-1.81.92.0-1.9-1.81.8-1.8-1.9-1.82.1-2.2-2.21.3-1.6-1.1
Locomotion velocity, session 20.20.20.9-0.4-0.5-0.5-0.40.50.5-0.5-0.30.3-0.5-0.4-0.50.4-0.6-0.5-0.0-1.00.1
Locomotion distance, session 22.12.94.2-1.8-1.8-1.7-1.61.81.8-1.8-1.71.7-1.7-1.7-1.71.9-2.0-1.91.3-1.6-0.6
Locomotion velocity, session 33.03.44.4-1.9-1.9-1.9-1.81.91.9-1.9-1.81.9-1.9-1.9-1.92.1-2.0-2.01.4-1.7-1.2
Locomotion distance, session 33.53.85.5-2.2-2.2-2.1-2.02.02.1-2.0-2.12.1-1.8-2.2-1.72.3-2.3-2.01.0-1.1-0.8
Stereotopy head waving bouts, day 30.30.40.80.80.70.70.7-0.6-0.60.60.9-0.90.50.80.4-0.20.70.1-0.2-0.10.4
Stereotopy head waving duration, day 30.10.10.20.40.40.30.3-0.2-0.20.20.5-0.50.10.50.10.20.4-0.20.2-0.30.1
Locomotion velocity, session 70.00.00.2-0.2-0.1-0.1-0.20.10.1-0.1-0.30.3-0.1-0.4-0.10.2-0.4-0.3-0.00.1-0.3
Locomotion distance, session 71.31.72.5-1.3-1.2-1.2-1.21.21.3-1.3-1.61.6-1.1-1.6-1.21.4-1.5-1.21.0-0.6-1.3
Stereotopy head waving bouts, day 71.61.82.91.41.41.41.4-1.5-1.51.41.3-1.31.41.31.5-1.01.40.9-1.71.21.2
Stereotopy head waving duration, day 72.22.63.71.61.61.61.6-1.7-1.71.71.6-1.61.71.61.8-1.51.81.3-1.91.11.5
Locomotion velocity, session 80.20.20.50.50.50.50.4-0.4-0.50.50.5-0.50.30.50.4-0.70.50.5-0.40.30.7
Locomotion distance, session 80.60.81.2-1.0-1.1-1.0-0.91.11.1-1.0-0.80.8-1.0-0.8-0.91.0-1.1-0.80.7-0.20.2
Degree of sensitization distance0.20.20.50.70.70.50.5-0.5-0.50.50.3-0.40.30.40.2-0.60.60.40.30.1-0.7
Degree of sensitization stereotypy1.11.22.11.01.01.01.0-1.2-1.21.10.9-1.01.11.01.3-1.01.20.9-1.50.90.9
Conditioned locomotion0.50.61.4-0.4-0.4-0.5-0.60.60.6-0.6-0.70.7-0.8-0.7-0.90.5-0.7-0.71.1-1.2-1.2
Cocaine response after cond. corrected0.20.32.00.1-0.1-0.2-0.00.40.4-0.30.3-0.3-0.60.3-0.70.2-0.2-0.61.1-1.40.1
Cocaine response after cond. not corrected1.41.75.0-1.0-1.2-1.2-1.11.41.4-1.3-0.80.7-1.5-0.8-1.61.1-1.1-1.41.7-2.2-0.8
Cocaine response before conditioning4.25.07.6-2.8-2.7-2.6-2.62.32.3-2.3-2.52.5-2.1-2.5-1.92.1-2.0-1.81.3-1.3-1.9
Saline control response0.10.10.2-0.4-0.5-0.4-0.40.40.4-0.4-0.20.2-0.4-0.2-0.4-0.2-0.10.20.2-0.50.0
Bone: connectivity density4.87.58.32.82.82.82.9-2.8-2.82.82.8-2.82.82.82.7-2.92.72.9-2.52.12.5
Bone: cortical apparent density1.01.43.6-0.9-1.0-1.1-1.01.31.2-1.2-0.60.6-1.4-0.7-1.51.3-1.0-1.61.4-1.9-0.7
Bone: cortical area9.815.117.24.14.14.14.1-4.1-4.04.03.9-3.94.03.93.9-3.63.73.6-3.73.63.5
Bone: cortical porosity1.82.02.7-1.6-1.6-1.6-1.61.61.5-1.5-1.21.2-1.5-1.3-1.51.0-1.3-1.01.6-1.1-1.2
Bone: cortical porosity1.41.52.4-1.6-1.5-1.5-1.51.51.4-1.4-1.01.0-1.4-1.1-1.20.8-1.1-0.81.4-0.8-0.9
Bone: cortical thickness4.47.38.82.82.72.82.9-2.7-2.72.72.8-2.82.82.82.7-2.42.52.4-2.72.23.0
Bone: cortical thickness0.20.30.90.50.50.60.7-0.5-0.40.50.4-0.40.60.30.5-0.2-0.00.4-0.60.70.9
Bone: cortical tissue density1.21.63.8-1.0-1.1-1.2-1.11.41.3-1.3-0.70.7-1.5-0.8-1.51.4-1.1-1.71.5-2.0-0.8
Condit. Reinf. active minus inactive responses0.30.30.6-0.4-0.5-0.5-0.40.60.5-0.5-0.50.5-0.6-0.5-0.70.8-0.7-0.60.6-0.5-0.2
Condit. Reinf. active-inactive response ratio0.10.10.20.30.30.30.3-0.3-0.30.30.2-0.20.30.30.2-0.10.10.2-0.30.30.4
Condit. Reinf. active responses0.91.11.7-1.0-1.0-1.0-1.01.11.1-1.1-1.11.1-1.1-1.1-1.21.3-1.3-1.11.2-0.6-0.7
Condit. Reinf. inactive responses3.54.35.5-2.0-2.0-2.0-2.02.12.1-2.1-2.12.1-2.1-2.1-2.12.1-2.1-2.12.4-1.5-2.1
Incentive salience index mean0.00.00.10.0-0.0-0.0-0.00.20.1-0.1-0.00.0-0.20.1-0.20.2-0.1-0.10.3-0.30.2
Condit. Reinf. lever presses0.10.10.30.40.30.20.3-0.1-0.20.20.5-0.5-0.00.6-0.0-0.40.40.30.3-0.40.4
Condit. Reinf. active minus inactive responses0.10.10.3-0.2-0.2-0.2-0.20.20.2-0.2-0.30.3-0.3-0.3-0.3-0.1-0.30.10.5-0.2-0.4
Condit. Reinf. active-inactive response ratio0.40.41.1-0.6-0.5-0.5-0.50.50.6-0.6-1.00.9-0.5-1.0-0.50.6-1.1-0.60.6-0.0-0.8
Condit. Reinf. active responses0.40.51.1-0.7-0.7-0.7-0.80.80.7-0.7-0.60.6-0.8-0.6-0.80.4-0.6-0.51.0-0.7-0.8
Condit. Reinf. inactive responses1.01.32.0-1.1-1.1-1.2-1.31.21.2-1.2-1.01.0-1.3-1.0-1.30.9-0.8-1.01.4-1.4-1.3
Condit. Reinf. lever presses0.20.31.10.20.20.30.3-0.3-0.40.40.4-0.40.40.30.5-1.00.51.0-0.60.90.9
Condit. Reinf. lever reinforcers received0.40.60.9-0.8-0.8-0.9-0.90.90.8-0.8-0.70.7-0.9-0.8-0.90.4-0.7-0.51.0-0.6-0.7
Conditioned reinforcement - actives0.10.20.5-0.6-0.7-0.7-0.60.70.6-0.6-0.40.3-0.7-0.4-0.60.3-0.3-0.10.3-0.20.2
Conditioned reinforcement - inactives1.42.03.2-1.6-1.7-1.6-1.61.61.5-1.5-1.81.8-1.5-1.5-1.40.7-1.0-0.71.3-0.6-1.1
Conditioned locomotion0.10.11.1-0.1-0.2-0.1-0.10.20.1-0.10.5-0.8-0.30.3-0.1-0.10.2-0.00.10.41.1
Patch foraging indifference point 0 sec0.61.02.9-1.3-1.2-1.1-1.10.80.9-0.9-1.61.5-0.6-1.7-0.50.4-1.2-0.70.1-0.1-0.8
Patch foraging indifference point AUC0.20.30.6-0.7-0.7-0.6-0.60.60.6-0.6-0.60.5-0.5-0.5-0.40.4-0.8-0.60.10.10.0
Delay disc. indifference point, 0s delay0.70.71.41.11.11.11.2-1.0-0.90.90.7-0.71.01.00.80.00.4-0.0-0.80.30.9
Delay disc. indifference point, 16s delay0.80.91.51.11.11.11.1-1.0-1.01.01.1-1.10.91.20.8-0.91.01.0-0.50.60.8
Delay disc. indifference point, 2s delay0.10.20.50.70.70.60.6-0.4-0.40.40.1-0.10.30.60.20.20.1-0.3-0.1-0.30.1
Delay disc. indifference point, 24s delay0.70.81.11.01.01.01.0-1.0-0.90.90.9-0.90.91.00.9-0.80.81.0-0.90.50.4
Delay disc. indifference point, 4s delay0.10.10.30.60.60.50.5-0.3-0.30.30.2-0.20.20.30.10.00.40.20.30.00.3
Delay disc. indifference point, 8s delay2.22.64.21.81.71.81.8-1.6-1.61.61.8-1.81.61.91.5-0.91.31.3-1.41.12.1
Indifference point function ln k1.32.23.71.91.91.91.8-1.8-1.71.61.7-1.61.61.41.4-0.71.10.9-1.30.70.7
Indifference point function log k1.32.23.71.91.91.91.8-1.8-1.71.61.7-1.61.61.41.4-0.71.10.9-1.30.70.7
Patch foraging total patch changes 0 sec0.51.02.7-1.3-1.2-1.1-1.10.90.9-0.9-1.51.4-0.6-1.6-0.50.4-1.1-0.60.1-0.1-0.6
Patch foraging total patch changes 12 sec0.30.40.9-1.0-0.8-0.7-0.70.50.5-0.5-0.80.7-0.3-0.9-0.0-0.5-0.40.2-0.30.80.1
Patch foraging total patch changes 18 sec1.21.83.7-1.7-1.6-1.6-1.71.31.3-1.3-1.91.7-1.1-1.7-0.90.6-0.9-0.90.7-0.1-1.5
Patch foraging total patch changes 24 sec0.40.71.7-1.0-1.0-1.0-1.10.90.8-0.8-1.00.9-0.9-0.9-0.70.2-0.5-0.30.6-0.5-1.3
Patch foraging total patch changes 6 sec1.32.04.1-1.7-1.6-1.5-1.51.31.4-1.4-2.01.9-1.1-2.0-1.01.0-1.5-1.20.6-0.5-0.9
Patch foraging time to switch 0 sec2.14.35.3-2.2-2.2-2.3-2.32.32.2-2.2-2.22.2-2.2-2.0-2.11.5-1.5-1.32.3-1.8-1.9
Patch foraging water rate 0 sec3.87.99.52.92.93.03.0-3.0-2.92.92.8-2.72.92.72.9-2.72.52.4-3.12.42.8
Patch foraging water rate 12 sec1.94.05.22.32.22.22.1-2.2-2.22.12.2-2.22.02.02.0-1.81.71.7-1.91.31.6
Patch foraging water rate 18 sec0.40.71.71.11.01.00.9-0.9-0.90.91.3-1.10.70.80.7-0.50.50.5-0.50.00.8
Patch foraging water rate 24 sec4.96.810.22.42.52.62.7-2.7-2.62.72.5-2.42.82.22.9-2.22.52.2-3.12.63.2
Patch foraging water rate 6 sec5.58.09.72.92.93.03.0-3.0-3.03.02.6-2.63.02.33.0-2.72.42.6-3.12.52.8
Seeking ratio, delayed vs. immediate footshock0.00.00.10.20.20.20.2-0.1-0.10.1-0.20.20.1-0.2-0.00.10.30.0-0.0-0.20.1
Distance traveled before self-admin0.10.20.7-0.6-0.5-0.4-0.40.30.3-0.3-0.90.8-0.1-0.5-0.00.40.0-0.3-0.40.5-0.1
Distance traveled after self-admin0.70.94.00.10.10.30.4-0.4-0.50.60.7-0.60.70.80.9-1.01.11.1-1.61.62.0
Extensor digitorum longus weight5.120.125.05.05.04.94.8-4.7-4.74.74.6-4.64.54.64.3-4.64.44.3-3.63.33.5
Bone: elastic displacement2.32.74.6-2.1-2.1-1.9-1.91.81.8-1.8-1.91.9-1.5-1.8-1.41.4-1.6-1.40.7-0.4-1.1
Bone: elastic work0.10.10.6-0.1-0.1-0.00.1-0.1-0.10.10.1-0.10.30.10.3-0.70.20.5-0.80.70.6
Bone: endosteal estimation6.714.617.44.14.24.14.0-4.0-4.14.03.6-3.73.93.73.9-3.93.94.0-3.23.72.6
Bone: endosteal perimeter6.413.615.93.94.03.93.9-3.9-3.93.93.5-3.53.83.63.8-3.63.73.8-3.13.82.7
Epididymis fat weight1.24.27.62.32.12.02.0-1.9-2.12.02.8-2.71.62.31.7-2.42.12.1-1.11.31.9
Delta time in closed arm before/after self-admin0.10.10.1-0.2-0.2-0.3-0.30.30.2-0.2-0.10.1-0.3-0.2-0.3-0.2-0.1-0.20.10.3-0.3
Delta time in open arm before/after self-admin0.60.61.0-0.8-0.8-0.7-0.70.70.7-0.7-0.80.8-0.7-0.7-0.71.0-0.8-1.00.5-0.5-0.5
Diff in mean of infusions in LGA sessions0.20.30.50.70.70.60.7-0.6-0.50.50.7-0.40.60.50.4-0.50.20.5-0.40.10.3
Delay discount exponential model param0.50.61.1-1.0-0.9-0.9-1.00.80.7-0.8-0.70.7-0.7-1.0-0.60.4-0.6-0.60.5-0.3-0.8
Extinction: sum of active levers before priming2.02.23.81.41.51.51.5-1.6-1.61.61.0-1.11.71.31.6-1.51.61.2-1.72.00.8
Active lever presses in extinction session 61.91.95.41.21.31.41.4-1.5-1.41.40.8-0.91.60.81.6-1.10.81.1-1.92.31.3
Bone: final force8.513.716.24.04.04.04.0-3.9-3.93.93.8-3.83.83.83.7-3.43.73.5-3.13.03.1
Bone: final moment8.814.216.94.14.14.04.0-3.9-3.93.93.9-3.93.83.93.7-3.63.83.7-3.23.13.2
Food consumed during 24 hour testing period1.01.41.81.21.21.11.2-1.1-1.11.11.2-1.21.01.21.0-1.21.21.3-1.01.31.3
Glucose0.10.10.30.40.30.20.2-0.1-0.10.10.1-0.1-0.00.2-0.10.40.1-0.60.5-0.4-0.3
Heart weight0.10.10.70.20.20.10.10.20.1-0.10.1-0.1-0.3-0.1-0.40.5-0.4-0.20.8-0.4-0.3
Delay discount hyperbolic model param0.40.40.9-0.9-0.8-0.8-0.90.60.6-0.6-0.50.5-0.6-0.9-0.40.3-0.5-0.40.2-0.1-0.7
Intermittent access intake day 1-15 change0.10.20.9-0.1-0.2-0.2-0.30.40.3-0.4-0.00.2-0.5-0.3-0.50.3-0.5-0.51.0-0.8-0.2
Intermittent access intake escalation0.00.10.50.20.10.10.10.10.0-0.00.3-0.1-0.20.1-0.2-0.0-0.2-0.20.7-0.60.1
Intermittent access intake escalation 20.10.10.60.20.20.20.2-0.2-0.20.20.10.00.20.40.2-0.80.50.80.10.30.6
Intermitt. access day 1 inactive lever presses0.51.94.0-1.4-1.3-1.4-1.51.31.3-1.3-1.61.8-1.3-1.6-1.31.2-1.2-0.81.2-0.8-2.0
Intermitt. access day 15 inactive lever presses0.91.82.6-1.2-1.2-1.3-1.21.31.4-1.4-1.21.3-1.3-1.4-1.41.6-1.6-1.61.4-0.7-1.1
Intermitt. access escalation Index1.01.43.20.81.01.00.9-1.3-1.21.2-0.00.11.40.71.5-1.61.61.3-1.81.70.0
Intermittent access day 1 total infusions0.71.21.9-1.1-1.1-1.1-1.01.11.1-1.1-1.21.0-1.0-1.3-1.11.3-1.4-1.30.7-0.4-0.7
Intermittent access day 15 total infusions0.60.81.5-0.7-0.8-0.8-0.80.90.9-0.9-0.70.8-0.9-0.9-1.00.8-1.1-1.11.2-1.0-0.9
Intermittent access terminal intake (last 3 days)1.11.52.4-1.1-1.1-1.2-1.21.21.2-1.2-1.11.1-1.3-1.2-1.41.0-1.3-1.21.5-1.4-1.2
Intermittent access total infusions0.80.91.4-1.0-1.0-1.0-1.01.01.0-1.0-1.00.9-0.9-1.1-0.90.8-1.2-0.90.8-0.5-0.7
Intermittent access day 1 locomotion0.10.20.7-0.3-0.3-0.3-0.40.30.3-0.4-0.20.0-0.5-0.4-0.50.6-0.3-0.90.5-0.4-0.6
Intermittent access day 15 total locomotion0.10.10.4-0.2-0.2-0.2-0.30.30.2-0.3-0.00.1-0.4-0.3-0.40.2-0.3-0.50.6-0.3-0.4
Intermittent access total locomotion0.30.30.7-0.6-0.6-0.7-0.70.70.6-0.6-0.10.0-0.8-0.4-0.70.6-0.4-0.80.8-0.3-0.4
Intermittent access standard deviation0.30.51.5-0.6-0.6-0.7-0.70.80.8-0.8-0.40.3-0.9-0.6-0.90.6-0.9-0.51.2-0.5-0.5
Left kidney weight0.62.84.52.12.02.02.1-1.8-1.71.81.8-1.71.71.91.5-1.41.31.0-1.31.41.5
Right kidney weight2.813.019.34.44.34.24.2-4.0-3.93.93.7-3.53.83.53.4-3.13.22.8-2.82.82.4
Cocaine induced anxiety2.73.84.62.12.12.01.9-2.0-2.02.02.1-2.11.82.01.9-1.82.01.9-1.91.81.6
Post-drug Anxiety5.05.37.82.22.22.22.2-2.1-2.32.32.3-2.32.12.42.2-2.72.52.8-2.32.02.4
Baseline Anxiety0.30.30.90.40.40.40.5-0.5-0.50.50.4-0.40.60.60.6-1.00.60.9-0.40.30.8
Tail length0.10.21.80.10.10.0-0.00.10.1-0.2-0.0-0.1-0.3-0.1-0.40.7-0.4-1.30.5-0.9-0.7
Length with tail1.04.36.62.62.62.52.5-2.4-2.32.32.3-2.42.22.12.0-1.71.30.9-1.81.41.3
Length without tail5.216.820.74.54.54.54.5-4.3-4.34.34.5-4.44.24.14.0-4.13.33.7-3.53.23.4
Times rat made contact with spout0.10.10.30.40.30.30.4-0.3-0.30.40.4-0.40.30.30.3-0.40.50.3-0.40.10.5
Lifetime Intake0.60.81.4-1.0-1.0-0.9-0.90.90.9-0.9-1.11.0-0.8-1.1-0.80.8-1.2-0.90.5-0.2-0.4
Liver weight, left6.110.212.23.53.53.43.4-3.3-3.33.33.3-3.33.23.33.1-3.13.52.9-2.72.72.5
Liver weight, right2.84.87.52.22.32.32.3-2.4-2.32.31.8-1.82.42.02.3-1.92.11.9-2.52.71.8
Locomotor activity0.81.21.8-1.2-1.2-1.2-1.21.21.1-1.1-1.41.2-1.1-1.2-1.11.1-0.9-1.01.1-0.8-0.9
Locomotor testing distance1.52.64.4-1.9-1.8-1.8-1.81.61.6-1.6-2.11.9-1.5-1.8-1.41.7-1.2-1.61.0-0.5-1.7
Locomotor testing rearing1.32.55.7-1.9-1.7-1.7-1.71.41.5-1.5-2.42.2-1.2-1.9-1.21.4-1.3-1.30.7-0.2-1.9
Locomotion in novel chamber1.21.52.21.41.41.41.5-1.4-1.31.41.2-1.21.41.01.3-0.91.01.0-1.40.70.9
Locomotion in novel chamber post-restriction0.10.10.50.50.40.40.4-0.3-0.40.30.3-0.30.20.40.2-0.20.40.2-0.1-0.70.5
Fecal boli incidents, locomotor time 10.40.51.0-0.7-0.9-0.8-0.60.90.9-0.8-0.20.2-0.9-0.3-0.91.0-0.8-0.60.6-0.60.9
Change in fecal boli incidents, locomotor task0.30.32.40.40.50.40.2-0.5-0.40.3-0.40.40.4-0.50.3-0.50.30.1-0.1-0.1-1.5
Time >=10cm from walls, locomotor time 11.01.13.30.80.81.01.1-1.0-0.91.00.8-0.81.11.01.1-0.60.60.3-1.61.31.8
Bouts of movement, locomotor time 10.20.20.70.30.30.30.3-0.2-0.20.20.8-0.80.20.70.10.10.40.2-0.2-0.70.5
Total resting periods, locomotor time 10.10.10.9-0.2-0.3-0.3-0.20.30.3-0.30.2-0.2-0.40.2-0.40.6-0.2-0.20.4-1.00.1
Rest time, locomotor task time 10.10.10.3-0.2-0.2-0.2-0.20.10.2-0.1-0.50.5-0.0-0.3-0.10.2-0.10.2-0.1-0.3-0.5
Distance moved, locomotor task time 10.10.21.1-0.2-0.1-0.00.1-0.0-0.00.10.1-0.10.20.10.3-0.0-0.0-0.3-0.71.01.0
Vertical activity count, locomotor time 10.71.84.21.21.21.31.4-1.3-1.21.31.3-1.31.41.21.4-1.11.00.9-1.51.62.1
Time >=10cm from walls, locomotor time 20.10.10.7-0.4-0.3-0.2-0.20.20.2-0.1-0.40.40.0-0.10.10.00.0-0.1-0.30.90.4
Bouts of movement, locomotor time 22.23.44.92.02.01.91.8-1.9-1.91.91.8-1.81.82.11.8-1.92.22.1-1.41.51.1
Total resting periods, locomotor time 21.73.14.12.02.01.91.8-1.9-1.91.81.8-1.81.72.01.6-1.62.01.8-1.21.20.9
Rest time, locomotor task time 20.10.11.20.20.20.10.0-0.1-0.00.0-0.30.3-0.1-0.2-0.20.2-0.0-0.10.4-1.1-0.9
Distance moved, locomotor task time 20.20.32.0-0.4-0.3-0.1-0.0-0.00.00.10.0-0.00.30.30.4-0.40.20.6-1.01.40.9
Vertical activity count, locomotor time 20.60.91.50.70.70.70.8-0.8-0.80.91.0-1.00.91.01.0-1.01.11.0-1.11.20.8
Light reinforcement 11.64.05.2-2.2-2.2-2.2-2.22.12.0-2.1-1.92.0-2.1-2.3-2.01.8-1.9-1.71.7-1.7-1.9
Light reinforcement 21.92.96.4-1.3-1.4-1.5-1.61.61.5-1.6-1.11.3-1.9-1.6-1.91.8-1.5-1.82.1-2.5-2.0
Bone: marrow area6.814.817.64.14.24.14.0-4.1-4.14.03.6-3.74.03.83.9-3.94.04.0-3.23.72.6
Bone: maximum diameter4.58.410.03.13.23.13.1-3.1-3.13.02.8-2.93.02.93.0-2.72.92.8-2.52.82.0
Bone: maximum force10.618.922.64.84.74.74.7-4.6-4.64.64.4-4.44.44.44.3-4.34.34.3-3.63.53.5
Bone: maximum moment10.919.122.94.84.84.74.7-4.6-4.64.64.4-4.44.44.44.3-4.34.34.4-3.63.63.5
Mean time between licks in bursts0.51.22.9-1.0-1.1-1.1-1.11.21.1-1.1-0.90.9-1.2-0.9-1.21.2-0.9-1.20.9-1.7-0.9
Mean num. licks in bursts0.10.21.40.30.20.20.4-0.1-0.10.20.5-0.50.20.40.2-0.60.40.60.00.31.2
Cd content in liver2.52.84.1-1.2-1.2-1.3-1.41.51.5-1.5-1.81.8-1.6-1.8-1.72.0-1.9-1.92.0-1.8-2.0
Co content in liver0.10.10.4-0.3-0.3-0.3-0.10.40.4-0.3-0.10.1-0.3-0.1-0.30.5-0.5-0.40.30.30.6
Cu content in liver3.33.96.11.81.91.91.9-2.0-2.02.01.7-1.72.11.72.1-1.81.92.1-2.32.51.8
Fe content in liver1.01.21.6-1.3-1.2-1.2-1.31.11.1-1.1-1.11.1-1.1-1.1-1.01.2-0.9-0.80.9-0.5-1.2
K content in liver0.60.61.01.00.91.01.0-0.9-0.80.80.7-0.70.90.70.7-0.50.50.5-0.60.80.9
Mg content in liver0.10.10.50.10.10.20.2-0.2-0.10.1-0.30.30.3-0.30.30.1-0.3-0.1-0.40.70.4
Mn content in liver0.10.10.40.10.10.0-0.00.00.1-0.1-0.10.1-0.1-0.1-0.20.1-0.0-0.30.6-0.5-0.6
Na content in liver0.50.52.10.50.60.60.5-0.7-0.70.70.2-0.20.80.20.8-0.80.50.9-0.91.40.0
Rb content in liver0.20.20.60.40.50.50.4-0.6-0.60.50.2-0.20.60.20.6-0.50.50.3-0.70.8-0.1
Se content in liver1.01.22.0-1.0-1.0-1.0-1.01.11.1-1.1-1.01.0-1.1-1.0-1.11.4-1.1-1.11.3-0.9-0.7
Sr content in liver2.32.02.91.41.41.41.4-1.4-1.41.41.5-1.51.41.51.4-1.41.41.7-1.21.41.3
Zn content in liver0.10.20.6-0.3-0.2-0.2-0.20.10.2-0.2-0.60.6-0.0-0.6-0.10.8-0.5-0.5-0.20.6-0.0
Bone: minimum diameter7.313.415.43.93.93.93.9-3.9-3.83.83.5-3.53.83.63.7-3.53.63.5-3.43.53.0
Time in familiar zone, hab. session 10.20.20.4-0.4-0.4-0.4-0.30.40.5-0.4-0.40.4-0.4-0.4-0.40.5-0.6-0.20.5-0.1-0.1
Time in novel zone, hab. session 10.10.10.30.20.20.20.0-0.2-0.30.20.2-0.20.10.20.2-0.50.50.1-0.1-0.0-0.4
Total zone transitions, hab. session 10.40.61.5-0.7-0.7-0.7-0.70.80.8-0.8-0.40.4-0.8-0.6-0.81.2-0.7-1.20.7-0.8-0.1
Total locomotion distance, hab. session 10.10.10.4-0.2-0.3-0.2-0.10.30.3-0.3-0.10.1-0.3-0.2-0.30.6-0.5-0.60.30.10.5
Locomotion velocity, hab. session 10.10.10.4-0.1-0.1-0.00.00.10.1-0.1-0.00.1-0.1-0.2-0.10.5-0.4-0.6-0.10.30.7
Time in familiar zone, hab. session 20.10.10.50.10.20.20.2-0.1-0.10.2-0.20.20.2-0.10.2-0.6-0.00.70.30.3-0.0
Time in novel zone, hab. session 20.10.10.4-0.1-0.2-0.2-0.30.20.2-0.20.1-0.1-0.40.0-0.30.40.1-0.60.1-0.4-0.5
Total zone transitions, hab. session 20.20.20.9-0.3-0.3-0.3-0.20.40.4-0.4-0.20.2-0.3-0.3-0.41.0-0.6-0.90.2-0.40.2
Total locomotion distance, hab. session 20.20.30.9-0.5-0.5-0.4-0.30.50.5-0.5-0.60.6-0.4-0.7-0.40.8-1.0-1.00.1-0.10.1
Locomotion velocity, hab. session 20.10.20.8-0.2-0.2-0.2-0.10.20.3-0.3-0.30.4-0.1-0.4-0.20.8-0.8-0.9-0.1-0.00.3
Novel to familiar place preference ratio0.50.60.90.90.90.90.7-0.9-0.90.80.6-0.60.80.50.7-1.00.70.9-0.60.6-0.1
Novelty place preference0.20.20.50.60.60.50.4-0.6-0.60.50.3-0.30.40.20.4-0.70.50.6-0.30.3-0.5
Time in novel zone, NPP test0.10.20.40.50.50.40.3-0.4-0.50.40.2-0.20.30.10.3-0.60.40.5-0.10.3-0.6
Total zone transitions, NPP test1.01.43.8-1.2-1.2-1.1-1.01.21.3-1.2-0.80.8-1.1-1.0-1.11.9-1.4-1.80.7-1.30.1
Total locomotion distance, NPP test2.63.56.1-1.9-1.9-1.8-1.71.92.0-1.9-1.81.8-1.8-2.0-1.82.4-2.3-2.51.2-1.6-0.7
Locomotion velocity, NPP test1.52.24.4-1.4-1.5-1.4-1.21.51.5-1.5-1.41.4-1.3-1.5-1.42.0-1.9-2.10.8-1.4-0.3
Intraocular pressure5.88.312.9-3.6-3.5-3.4-3.33.33.2-3.1-3.02.9-3.0-3.0-2.72.6-2.7-2.02.2-1.8-1.4
Delta distance traveled before/after self-admin0.30.31.40.30.20.30.3-0.3-0.40.40.9-0.80.30.50.5-0.60.10.6-0.90.51.2
Delta ambulatory time before/after self-admin0.20.31.30.20.10.20.2-0.2-0.30.30.9-0.80.20.50.4-0.60.30.6-0.80.31.1
Parametrial fat weight0.10.21.2-0.6-0.6-0.5-0.40.50.4-0.40.2-0.1-0.40.0-0.20.2-0.40.3-0.10.61.1
Pavlov. Cond. lever latency0.10.20.90.30.40.40.3-0.5-0.40.4-0.10.10.6-0.20.6-0.20.00.3-0.61.0-0.2
Pavlov. Cond. magazine entry latency0.00.10.1-0.3-0.3-0.3-0.20.30.3-0.2-0.00.0-0.20.1-0.2-0.3-0.00.30.30.20.4
Pavlov. Cond. change in total contacts0.10.10.7-0.1-0.2-0.3-0.30.40.3-0.3-0.20.2-0.5-0.0-0.50.2-0.2-0.10.8-0.6-0.3
Pavlov. Cond. index score0.10.20.60.30.20.20.3-0.2-0.30.30.6-0.60.20.80.2-0.50.60.6-0.10.10.6
Pavlov. Cond. latency score0.10.10.40.20.10.10.10.0-0.10.10.5-0.5-0.10.7-0.0-0.40.40.40.1-0.20.6
Pavlov. Cond. lever contacts0.50.71.9-0.7-0.8-0.9-0.81.00.8-0.9-0.50.4-1.0-0.2-1.00.6-0.5-0.71.0-1.4-0.3
Pavlov. Cond. magazine entry number0.10.10.5-0.0-0.0-0.1-0.10.00.1-0.1-0.40.4-0.1-0.5-0.10.5-0.3-0.60.1-0.5-0.7
Pavlov. Cond. intertrial magazine entries0.80.91.2-0.8-0.8-0.9-0.81.01.0-1.0-1.01.0-1.0-1.1-1.01.0-1.1-1.01.1-0.7-0.7
Pavlov. Cond. lever-magazine prob. diff.0.40.51.10.60.60.60.6-0.5-0.60.60.9-0.90.51.10.5-0.80.90.9-0.40.40.8
Pavlov. Cond. response bias0.10.10.2-0.4-0.4-0.4-0.30.50.4-0.4-0.00.1-0.40.1-0.4-0.1-0.10.00.4-0.30.2
Pavlov. Cond. lever latency0.10.10.60.30.30.20.1-0.1-0.10.10.1-0.00.00.1-0.10.6-0.0-0.50.2-0.6-0.8
Pavlov. Cond. magazine entry latency0.20.30.80.40.50.50.5-0.5-0.50.50.2-0.20.60.20.5-0.70.30.5-0.70.90.5
Pavlov. Cond. change in total contacts0.91.52.61.21.21.21.2-1.2-1.21.21.1-1.11.21.01.2-1.61.21.5-1.01.31.4
Pavlov. Cond. index score0.60.81.90.60.60.70.8-0.8-0.80.80.5-0.60.90.50.9-1.10.61.0-1.21.41.3
Pavlov. Cond. latency score0.60.71.70.60.60.70.8-0.8-0.80.80.5-0.50.90.50.9-1.10.61.0-1.21.31.3
Pavlov. Cond. lever contacts0.10.21.0-0.1-0.10.00.1-0.1-0.10.10.0-0.00.2-0.00.3-0.70.10.6-0.50.91.0
Pavlov. Cond. magazine entry number1.11.31.7-1.2-1.2-1.2-1.21.21.2-1.2-0.90.9-1.2-0.9-1.21.3-1.0-1.11.2-1.3-0.9
Pavlov. Cond. intertrial magazine entries1.82.73.8-1.9-1.9-1.9-1.81.81.8-1.8-1.51.5-1.7-1.5-1.61.9-1.6-1.61.1-1.2-0.7
Pavlov. Cond. lever-magazine prob. diff.0.71.02.10.70.70.90.9-0.9-0.90.90.7-0.71.00.61.1-1.20.81.1-1.31.51.4
Pavlov. Cond. response bias0.10.20.80.10.10.10.2-0.2-0.20.20.1-0.10.30.10.4-0.70.20.6-0.50.90.8
Time in closed arm before self-admin0.50.61.21.11.11.11.1-0.9-0.80.81.0-1.00.80.60.60.2-0.1-0.2-0.40.10.4
Time in closed arm after self-admin0.20.21.2-0.1-0.0-0.1-0.10.00.2-0.2-0.30.4-0.0-0.5-0.10.6-0.6-1.1-0.20.2-0.8
Time in open arm before self-admin0.10.11.5-0.1-0.0-0.1-0.30.10.0-0.1-0.40.4-0.2-0.4-0.1-0.30.10.40.4-0.0-1.2
Time in open arm after self-admin0.20.20.7-0.2-0.2-0.3-0.40.30.3-0.3-0.00.0-0.5-0.2-0.50.4-0.0-0.10.8-0.6-0.8
Bone: periosteal estimation11.223.727.45.25.25.25.1-5.1-5.15.14.8-4.85.04.84.9-4.64.94.7-4.34.63.8
Bone: periosteal perimeter10.718.521.04.54.64.64.6-4.5-4.44.54.2-4.24.54.24.4-4.14.14.2-3.94.23.6
Bone: post-yield work7.410.913.03.63.63.53.4-3.4-3.53.43.5-3.63.23.63.2-3.53.63.3-2.42.32.3
Progressive ratio test 1 active lever presses1.82.23.3-1.8-1.8-1.7-1.61.61.6-1.6-1.61.5-1.5-1.5-1.41.8-1.4-1.70.8-0.5-0.4
Progressive ratio test 1 breakpoint1.51.92.9-1.7-1.7-1.5-1.51.51.5-1.5-1.41.3-1.4-1.4-1.21.7-1.3-1.60.7-0.4-0.3
Progressive ratio test 1 inactive lever presses1.11.62.9-1.2-1.1-1.1-1.21.11.2-1.2-1.71.7-1.1-1.5-1.21.2-1.4-1.11.1-0.0-1.6
Progressive ratio test 2 active lever presses0.70.81.6-1.0-0.9-0.9-1.00.80.8-0.9-1.31.2-0.8-1.2-0.80.8-0.8-0.70.7-0.3-1.2
Progressive ratio test 2 breakpoint0.80.91.7-0.9-0.9-0.9-1.00.80.8-0.9-1.31.2-0.8-1.1-0.80.8-0.8-0.70.8-0.3-1.3
Progressive ratio test 2 inactive lever presses0.71.22.7-1.1-1.1-1.0-1.11.01.0-1.0-1.61.7-0.9-1.5-0.91.0-1.1-0.70.7-0.1-1.2
Incentive Sensitization - Responses0.20.31.00.50.60.50.4-0.6-0.60.5-0.30.20.6-0.00.4-0.50.30.6-0.10.5-1.0
Incentive Sensitization - Breakpoint0.20.21.50.40.50.40.2-0.5-0.40.4-0.50.40.4-0.10.3-0.40.30.60.00.4-1.2
Sum of active levers in priming session hrs 5-60.10.10.4-0.2-0.1-0.2-0.20.10.1-0.1-0.10.0-0.10.0-0.0-0.20.40.2-0.0-0.3-0.7
Progressive ratio0.00.10.4-0.2-0.1-0.0-0.0-0.00.1-0.0-0.40.40.2-0.60.20.2-0.1-0.2-0.50.10.2
Food seeking constrained by brief footshock0.81.03.40.30.30.50.5-0.6-0.70.70.5-0.50.80.81.1-1.60.81.3-1.41.81.7
Seeking ratio, punishment vs. effort0.10.10.60.10.10.10.0-0.1-0.20.20.4-0.40.00.80.1-0.60.40.50.00.50.3
Retroperitoneal fat weight0.10.51.8-0.4-0.5-0.6-0.70.80.6-0.60.3-0.3-1.0-0.0-0.90.4-0.5-0.31.3-1.1-0.4
Reaction time number correct0.51.01.30.90.90.90.9-0.9-1.01.01.1-1.10.91.11.0-1.00.81.0-1.10.71.0
Reaction time mean minus median5.112.717.4-3.7-3.7-3.8-3.63.93.9-3.8-3.63.4-3.8-3.2-3.83.2-2.9-3.14.2-3.2-3.0
Reaction time mean minus median AUC3.38.411.6-3.0-3.1-3.2-3.03.23.2-3.1-2.92.8-3.1-2.6-3.22.4-2.2-2.43.4-2.8-2.4
Reaction time num false alarms1.41.93.8-1.5-1.4-1.3-1.21.31.4-1.3-1.71.7-1.1-1.4-1.11.7-1.9-1.80.6-0.9-0.6
Reaction time num false alarms AUC1.93.05.1-1.9-1.9-1.7-1.61.71.8-1.7-2.22.1-1.4-1.8-1.41.9-2.3-2.00.9-1.1-0.7
Reaction time trials correct on left0.51.01.30.90.90.90.9-0.9-1.01.01.1-1.10.91.11.0-1.00.81.0-1.10.71.0
Reaction time trials on left0.40.71.00.70.70.80.7-0.8-0.90.80.9-1.00.81.00.9-0.90.70.9-1.00.60.9
Reaction time mean0.60.92.3-1.0-1.1-1.1-1.01.21.1-1.0-0.90.8-1.2-0.3-1.20.4-0.1-0.21.5-1.1-0.5
Reaction time mean AUC0.30.41.2-0.7-0.8-0.8-0.70.80.8-0.7-0.60.5-0.80.0-0.80.10.20.21.1-0.8-0.1
Median of all reaction times0.10.21.00.20.10.10.1-0.0-0.10.20.3-0.30.00.90.0-0.71.00.90.2-0.00.6
Reaction time omissions6.59.412.7-3.6-3.5-3.5-3.33.53.5-3.3-3.33.1-3.2-2.8-3.22.4-2.4-2.23.3-2.2-2.2
Reaction time false alarm rate1.92.64.1-1.7-1.7-1.6-1.41.51.7-1.6-2.02.0-1.3-1.7-1.41.8-2.0-1.91.0-1.1-0.8
Reaction time premature initiation rate1.31.83.3-1.8-1.8-1.7-1.61.61.5-1.5-1.11.0-1.4-1.2-1.21.2-1.4-1.10.9-0.7-0.5
Reaction time premature initiations0.50.81.8-1.3-1.3-1.2-1.21.11.0-1.0-0.60.5-1.0-0.7-0.80.6-0.9-0.50.5-0.4-0.2
Std. dev. reaction times5.19.414.1-3.2-3.2-3.3-3.23.43.4-3.3-3.12.9-3.4-2.5-3.42.5-2.2-2.43.8-2.9-2.6
Reaction time trials completed0.40.71.00.70.70.80.7-0.8-0.90.80.9-1.00.81.00.9-0.90.70.9-1.00.60.9
Reaction time trials AUC0.71.31.81.11.11.11.0-1.1-1.21.21.3-1.31.11.31.2-1.20.91.2-1.30.91.2
Run reversals in cocaine runway, females0.40.41.3-0.6-0.4-0.4-0.40.20.4-0.4-1.01.0-0.1-1.1-0.10.9-0.5-0.9-0.40.2-0.8
Run reversals in cocaine runway, males1.81.84.9-1.0-1.2-1.2-1.11.31.4-1.3-0.90.9-1.4-1.1-1.51.4-1.3-2.01.5-2.2-0.6
Latency to leave start box in cocaine runway0.20.20.9-0.2-0.3-0.3-0.40.40.4-0.40.00.1-0.5-0.0-0.50.4-0.1-0.70.7-1.0-0.5
Latency to leave start box in cocaine runway, F1.11.21.5-1.2-1.1-1.2-1.21.11.2-1.1-1.11.2-1.1-0.9-1.11.1-0.8-1.21.1-1.1-1.1
Latency to leave start box in cocaine runway, M1.61.52.31.41.31.31.2-1.2-1.31.31.5-1.51.11.41.1-1.11.30.8-0.80.60.9
Std. dev. time between licks in bursts0.40.51.0-1.0-1.0-1.0-0.90.90.8-0.8-0.60.6-0.9-0.6-0.70.4-0.4-0.40.4-0.4-0.3
Total sessions with >9 infusions0.70.82.4-0.8-0.8-0.7-0.60.80.9-0.8-0.90.8-0.7-1.2-0.81.4-1.5-1.40.5-0.2-0.2
Short access day 1 total inactive lever presses0.70.91.8-1.1-1.1-1.0-0.91.01.0-1.0-1.11.3-0.8-1.2-0.81.1-1.3-1.00.3-0.1-0.2
Short access day 10 total inactive lever presses0.00.10.8-0.3-0.3-0.2-0.20.20.2-0.2-0.50.6-0.1-0.3-0.0-0.1-0.10.20.00.90.0
Short access day 1 total infusions0.10.20.6-0.4-0.3-0.2-0.20.20.4-0.3-0.70.6-0.1-0.7-0.20.6-0.8-0.6-0.1-0.1-0.2
Short access day 10 total infusions1.31.74.4-1.0-1.1-1.0-1.01.21.3-1.3-1.00.9-1.2-1.4-1.32.0-2.1-1.91.0-1.2-0.6
Short access total infusions0.70.81.7-1.0-1.0-0.9-0.90.90.9-0.9-1.11.0-0.7-1.2-0.71.0-1.3-1.10.3-0.2-0.5
Short access day 1 locomotion0.20.31.1-0.0-0.0-0.0-0.10.20.3-0.3-0.1-0.0-0.3-0.4-0.41.1-1.0-1.10.5-0.6-0.3
Short access day 10 total locomotion0.40.82.7-0.5-0.6-0.6-0.70.80.8-0.8-0.1-0.1-1.0-0.7-1.11.5-1.1-1.61.1-0.7-0.4
Short access total locomotion0.60.72.6-0.6-0.6-0.6-0.60.80.8-0.8-0.1-0.0-0.9-0.7-0.91.4-1.2-1.60.8-0.6-0.1
One hour access (0.3 mA shock)0.10.10.7-0.1-0.1-0.2-0.20.20.2-0.2-0.80.8-0.1-0.4-0.30.0-0.20.20.50.3-0.7
Compulsive drug intake0.20.20.4-0.4-0.4-0.4-0.50.40.4-0.5-0.60.5-0.5-0.6-0.50.4-0.6-0.40.4-0.7-0.6
One hour access (shock baseline)0.00.10.20.40.40.30.3-0.3-0.30.30.1-0.10.30.20.1-0.30.30.30.20.3-0.3
Social response proportion1.01.12.9-0.8-0.8-0.8-0.80.80.9-0.9-1.41.5-0.7-1.7-0.90.8-1.3-0.80.8-0.9-1.2
Social responses7.79.914.2-3.3-3.2-3.2-3.13.13.2-3.1-3.83.8-2.9-3.8-2.92.7-3.3-2.72.8-2.4-3.1
Social time1.62.24.6-1.1-1.2-1.3-1.41.41.4-1.4-1.61.5-1.6-1.2-1.71.2-1.2-1.12.1-1.6-2.1
Soleus weight0.92.53.91.81.81.71.7-1.6-1.71.71.9-1.91.52.01.4-1.11.81.2-1.00.91.4
Bone: stiffness12.420.124.85.05.04.94.8-4.8-4.74.74.5-4.54.64.54.4-4.54.44.5-3.53.63.4
Tibialis anterior weight2.06.88.83.02.92.92.9-2.8-2.82.82.7-2.72.62.72.5-2.42.52.4-2.11.82.0
Time to tail flick, vehicle, before self-admin0.90.93.0-1.3-1.2-1.1-1.01.01.0-0.9-1.71.6-0.7-0.9-0.60.1-0.4-0.20.40.3-0.3
Time to tail flick, vehicle, after self-admin0.10.21.1-0.3-0.3-0.3-0.30.30.3-0.3-0.50.5-0.3-0.5-0.40.1-0.4-0.20.5-0.1-1.1
Time to tail flick, test, before self-admin0.80.93.1-0.8-0.7-0.7-0.70.60.8-0.7-1.71.7-0.5-1.2-0.70.5-1.0-0.50.4-0.6-1.3
Time to tail flick, test, after self-admin0.30.33.50.20.30.1-0.0-0.10.0-0.1-0.50.8-0.1-0.2-0.30.2-0.1-0.20.5-0.6-1.9
Delta time to tail flick, vehicle, before/after SA0.20.20.40.50.50.40.3-0.4-0.40.40.6-0.60.30.40.3-0.50.30.6-0.20.4-0.1
Delta time to tail flick, test, before/after SA0.30.31.20.30.30.1-0.00.00.0-0.10.6-0.5-0.30.3-0.40.50.1-0.60.9-1.1-1.1
Tibia length6.818.721.94.34.44.44.4-4.6-4.54.53.9-3.94.64.04.7-4.54.34.4-4.54.53.3
Ambulatory time before self-admin0.71.02.3-1.2-1.2-1.0-1.00.91.0-1.0-1.51.5-0.7-1.2-0.61.2-0.8-1.10.10.1-0.4
Ambulatory time after self-admin0.50.63.1-0.4-0.3-0.1-0.0-0.1-0.20.20.2-0.10.40.30.7-0.60.70.6-1.51.71.7
Bone: tissue strength0.30.30.70.60.50.40.4-0.4-0.50.50.6-0.60.30.60.3-0.90.80.7-0.1-0.3-0.0
Total heroin consumption1.82.13.71.31.41.41.3-1.5-1.51.51.4-1.31.51.21.6-1.51.21.5-1.71.91.1
Bone: trabecular number4.16.77.72.62.62.72.8-2.6-2.62.72.6-2.62.72.62.6-2.72.42.7-2.42.22.6
Bone: trabecular spacing1.31.83.2-1.3-1.2-1.3-1.41.21.2-1.3-1.01.0-1.4-1.0-1.31.7-0.9-1.61.4-1.6-1.8
Bone: trabecular thickness0.20.30.8-0.6-0.5-0.5-0.40.60.6-0.5-0.80.8-0.4-0.8-0.50.3-0.9-0.30.3-0.1-0.1
Bone: trabecular tissue density0.30.51.4-0.4-0.5-0.5-0.60.60.6-0.6-0.40.4-0.8-0.5-0.80.8-0.5-0.90.9-1.2-0.7
Water consumed over 24 hours0.30.41.20.70.60.50.5-0.4-0.50.50.8-0.80.30.80.3-1.10.90.9-0.00.10.4
Number of responses in last shaping day0.40.51.70.0-0.0-0.1-0.20.40.4-0.4-0.10.1-0.6-0.6-0.81.2-1.3-1.01.0-0.9-0.7