Amigo2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc intron excision ratio chr7_130273092_130273443 0.01 0.01 5.1e-03 0.01 0.01 0.01 -0 1.4e-02 5.0e-03 1.7e-02 5.0e-01
2 NAcc isoform ratio XM_063263370.1 0.01 0.01 4.3e-03 0.01 0.01 0.01 0.01 2.7e-02 2.2e-03 7.6e-03 7.2e-03
3 BLA gene expression Amigo2 0.04 0.03 6.0e-03 0.03 0.04 0.02 0.03 1.5e-02 3.1e-03 4.4e-02 7.9e-03
4 Brain gene expression Amigo2 0.07 0.04 9.1e-10 0.09 0.11 0.1 0.1 1.7e-08 4.0e-10 7.7e-10 1.9e-09
5 pVTA alternative TSS XM_063263370.1 0.03 0.03 2.3e-03 0.02 0.03 0.02 0.02 1.5e-02 1.2e-03 1.4e-02 1.2e-02
6 NAcc isoform ratio NM_182816.3 0.03 0.02 1.2e-05 0.03 0.03 0.03 0.03 8.7e-05 7.9e-06 1.7e-05 9.3e-05
7 IL gene expression Amigo2 0.09 0.07 8.2e-03 0.04 0.08 0.06 0.07 3.5e-02 6.8e-03 1.2e-02 8.0e-03
8 PL gene expression Amigo2 0.05 0.06 9.7e-04 0.02 0.01 0.01 0.01 6.7e-03 1.1e-02 7.2e-02 2.1e-02
9 pVTA gene expression Amigo2 0.11 0.06 3.6e-11 0.13 0.12 0.13 0.13 7.7e-11 1.2e-09 1.2e-10 1.3e-10
10 IC isoform ratio XM_063263369.1 0.06 0.05 7.0e-03 0.02 0.04 0.02 0.01 4.8e-02 7.1e-03 6.1e-02 9.0e-02
11 Liver gene expression Amigo2 0.22 0.11 0.0e+00 0.27 0.26 0.27 0.27 5.1e-30 3.2e-28 7.7e-30 6.5e-30
12 pVTA intron excision ratio chr7_130273092_130273443 0.06 0.04 4.8e-06 0.02 0.07 0.05 0.05 7.2e-03 5.5e-06 4.0e-05 9.0e-05
13 Eye isoform ratio NM_182816.3 0.2 0.15 5.6e-03 0.1 0.06 0.03 0.07 1.4e-02 4.4e-02 1.1e-01 3.0e-02
14 Adipose gene expression Amigo2 0.15 0.08 0.0e+00 0.14 0.15 0.16 0.15 3.6e-15 1.0e-16 3.3e-17 8.3e-17
15 LHb intron excision ratio chr7_130273092_130273443 0.5 0.26 7.5e-03 0.09 0.03 0.07 0.08 3.7e-03 7.1e-02 8.3e-03 5.6e-03
16 IC isoform ratio NM_182816.3 0.07 0.05 6.1e-03 0.05 0.05 0.05 0.06 3.6e-03 4.4e-03 3.2e-03 2.5e-03
17 Liver intron excision ratio chr7_130273092_130273443 0.14 0.11 1.9e-04 0.03 0.02 0.03 0.03 1.9e-04 1.7e-03 8.0e-04 2.2e-04
18 IC gene expression Amigo2 0.42 0.17 3.4e-04 0.05 0.1 0.07 0.06 4.0e-03 4.3e-05 5.7e-04 1.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density6.111.313.03.53.53.53.6-3.5-3.43.5-3.33.33.5-3.33.43.3-3.2-3.3-3.3-2.93.3
Area under the delay curve0.40.71.31.11.01.01.1-0.9-0.80.9-0.80.80.8-1.10.70.4-0.6-0.6-0.5-0.31.0
BMI with tail4.716.323.24.64.54.54.5-4.1-4.14.2-4.84.63.9-4.23.73.2-3.4-3.3-3.1-2.94.0
BMI without tail0.73.96.52.42.32.32.4-2.0-2.02.1-2.62.51.9-2.01.81.1-1.5-0.9-1.4-1.32.2
Body weight4.419.327.35.25.15.05.0-4.7-4.74.7-5.25.04.4-4.64.13.5-3.5-3.0-3.4-3.03.7
Weight adjusted by age0.41.12.41.61.51.41.4-1.3-1.21.1-1.21.21.1-0.90.80.4-0.3-0.2-0.4-0.10.1
Bone surface7.514.716.94.14.14.04.1-3.9-3.94.0-4.04.03.8-4.03.73.9-3.9-3.9-3.2-3.23.4
Bone volume4.89.611.23.33.33.33.3-3.2-3.23.2-3.23.23.1-3.23.03.1-3.1-3.1-2.6-2.62.8
Breakpoint value in progressive ratio session1.73.05.11.41.51.61.6-1.7-1.71.7-1.61.61.9-1.62.01.7-1.7-1.7-2.1-2.31.9
Number of licking bursts0.10.31.2-0.5-0.5-0.5-0.60.30.4-0.40.6-0.6-0.40.6-0.4-0.70.50.7-0.10.4-1.1
Context. condit. distance diff. score0.50.61.70.80.80.80.7-0.7-0.70.7-0.80.80.7-0.80.70.8-0.8-0.9-0.3-1.30.6
Locomotion velocity, session 11.01.11.9-0.8-0.8-0.8-0.90.80.9-0.91.2-1.2-0.91.2-0.9-1.31.21.30.81.4-1.3
Locomotion distance, session 12.73.44.9-1.9-1.9-1.9-1.81.92.0-1.91.8-1.8-1.81.9-1.8-2.12.22.21.31.6-1.1
Locomotion velocity, session 20.20.20.9-0.4-0.5-0.5-0.40.50.5-0.50.3-0.3-0.50.4-0.5-0.40.60.5-0.01.00.1
Locomotion distance, session 22.12.94.2-1.8-1.8-1.7-1.61.81.8-1.81.7-1.7-1.71.7-1.7-1.92.01.91.31.6-0.6
Locomotion velocity, session 33.03.44.4-1.9-1.9-1.9-1.81.91.9-1.91.8-1.9-1.91.9-1.9-2.12.02.01.41.7-1.2
Locomotion distance, session 33.33.85.5-2.2-2.2-2.1-2.02.02.1-2.02.1-2.1-1.82.2-1.7-2.32.32.01.01.1-0.8
Stereotopy head waving bouts, day 30.30.40.80.80.70.70.7-0.6-0.60.6-0.90.90.5-0.80.40.2-0.7-0.1-0.20.10.4
Stereotopy head waving duration, day 30.10.10.20.40.40.30.3-0.2-0.20.2-0.50.50.1-0.50.1-0.2-0.40.20.20.30.1
Locomotion velocity, session 70.00.00.2-0.2-0.1-0.1-0.20.10.1-0.10.3-0.3-0.10.4-0.1-0.20.40.3-0.1-0.1-0.3
Locomotion distance, session 71.31.72.5-1.3-1.2-1.2-1.21.21.3-1.31.6-1.6-1.11.6-1.2-1.41.51.21.00.6-1.3
Stereotopy head waving bouts, day 71.61.82.91.41.41.41.4-1.5-1.51.4-1.31.31.4-1.31.51.0-1.4-0.9-1.7-1.21.2
Stereotopy head waving duration, day 72.12.63.71.61.61.61.6-1.7-1.71.7-1.61.61.7-1.61.81.5-1.8-1.3-1.9-1.11.5
Locomotion velocity, session 80.20.20.50.50.50.50.4-0.4-0.50.5-0.50.50.3-0.50.40.7-0.5-0.5-0.4-0.30.7
Locomotion distance, session 80.60.81.2-1.0-1.1-1.0-0.91.11.1-1.00.8-0.8-1.00.8-0.9-1.01.10.80.70.20.2
Degree of sensitization distance0.20.20.50.70.70.50.5-0.5-0.50.5-0.30.40.3-0.40.20.6-0.6-0.40.3-0.1-0.7
Degree of sensitization stereotypy1.01.22.11.01.01.01.0-1.2-1.21.1-0.91.01.1-1.01.31.0-1.2-0.9-1.5-0.90.9
Conditioned locomotion0.50.61.4-0.4-0.4-0.5-0.60.60.6-0.60.7-0.7-0.80.7-0.9-0.50.70.71.11.2-1.2
Cocaine response after cond. corrected0.20.32.00.1-0.1-0.2-0.00.40.4-0.3-0.30.3-0.6-0.3-0.7-0.20.20.61.11.40.1
Cocaine response after cond. not corrected1.21.75.0-1.0-1.2-1.2-1.11.41.4-1.30.8-0.7-1.50.8-1.6-1.11.11.41.72.2-0.8
Cocaine response before conditioning4.15.07.6-2.8-2.7-2.6-2.62.32.3-2.32.5-2.5-2.12.5-1.9-2.12.01.81.21.3-1.9
Saline control response0.10.10.2-0.4-0.5-0.4-0.40.40.4-0.40.2-0.2-0.40.2-0.40.20.1-0.20.20.50.0
Bone: connectivity density4.77.58.32.82.82.82.9-2.8-2.82.8-2.82.82.8-2.82.72.9-2.7-2.9-2.5-2.12.5
Bone: cortical apparent density0.91.43.6-0.9-1.0-1.1-1.01.31.2-1.20.6-0.6-1.40.7-1.5-1.31.01.61.41.9-0.7
Bone: cortical area9.315.117.24.14.14.14.1-4.1-4.04.0-3.93.94.0-3.93.93.6-3.7-3.6-3.7-3.63.5
Bone: cortical porosity1.82.02.7-1.6-1.6-1.6-1.61.61.5-1.51.2-1.2-1.51.3-1.5-1.01.31.01.61.1-1.2
Bone: cortical porosity1.41.52.4-1.6-1.5-1.5-1.51.51.4-1.41.0-1.0-1.41.1-1.2-0.81.10.81.40.8-0.9
Bone: cortical thickness4.47.38.82.82.72.82.9-2.7-2.72.7-2.82.82.8-2.82.72.4-2.5-2.4-2.7-2.23.0
Bone: cortical thickness0.20.30.90.50.50.60.7-0.5-0.40.5-0.40.40.6-0.30.50.20.0-0.4-0.6-0.70.9
Bone: cortical tissue density1.01.63.8-1.0-1.1-1.2-1.11.41.3-1.30.7-0.7-1.50.8-1.5-1.41.11.71.52.0-0.8
Condit. Reinf. active minus inactive responses0.30.30.6-0.4-0.5-0.5-0.40.60.5-0.50.5-0.5-0.60.5-0.7-0.80.70.60.60.5-0.2
Condit. Reinf. active-inactive response ratio0.10.10.20.30.30.30.3-0.3-0.30.3-0.20.20.3-0.30.20.1-0.1-0.2-0.3-0.30.4
Condit. Reinf. active responses0.91.11.7-1.0-1.0-1.0-1.01.11.1-1.11.1-1.1-1.11.1-1.2-1.31.31.11.20.6-0.7
Condit. Reinf. inactive responses3.34.35.5-2.0-2.0-2.0-2.02.12.1-2.12.1-2.1-2.12.1-2.1-2.12.12.12.41.5-2.1
Incentive salience index mean0.00.00.10.0-0.0-0.0-0.00.20.1-0.10.0-0.0-0.2-0.1-0.2-0.20.10.10.30.30.2
Condit. Reinf. lever presses0.10.10.30.40.30.20.3-0.1-0.20.2-0.50.5-0.0-0.6-0.00.4-0.4-0.30.30.40.4
Condit. Reinf. active minus inactive responses0.00.10.3-0.2-0.2-0.2-0.20.20.2-0.20.3-0.3-0.30.3-0.30.10.3-0.10.50.2-0.4
Condit. Reinf. active-inactive response ratio0.30.41.1-0.6-0.5-0.5-0.50.50.6-0.61.0-0.9-0.51.0-0.5-0.61.10.60.60.0-0.8
Condit. Reinf. active responses0.40.51.1-0.7-0.7-0.7-0.80.80.7-0.70.6-0.6-0.80.6-0.8-0.40.60.51.00.7-0.8
Condit. Reinf. inactive responses0.91.32.0-1.1-1.1-1.2-1.31.21.2-1.21.0-1.0-1.31.0-1.3-0.90.81.01.41.4-1.3
Condit. Reinf. lever presses0.20.31.10.20.20.30.3-0.3-0.40.4-0.40.40.4-0.30.51.0-0.5-1.0-0.6-0.90.9
Condit. Reinf. lever reinforcers received0.40.60.9-0.8-0.8-0.9-0.90.90.8-0.80.7-0.7-0.90.8-0.9-0.40.70.51.00.6-0.7
Conditioned reinforcement - actives0.10.20.5-0.6-0.7-0.7-0.60.70.6-0.60.4-0.3-0.70.4-0.6-0.30.30.10.30.20.2
Conditioned reinforcement - inactives0.72.03.2-1.6-1.7-1.6-1.61.61.5-1.51.8-1.8-1.51.5-1.4-0.71.00.71.30.6-1.1
Conditioned locomotion0.10.11.1-0.1-0.2-0.1-0.10.20.1-0.1-0.50.8-0.3-0.3-0.10.1-0.20.00.1-0.41.1
Patch foraging indifference point 0 sec0.41.02.9-1.3-1.2-1.1-1.10.80.9-0.91.6-1.5-0.61.7-0.5-0.41.20.70.10.1-0.8
Patch foraging indifference point AUC0.10.30.6-0.7-0.7-0.6-0.60.60.6-0.60.6-0.5-0.50.5-0.4-0.40.80.60.1-0.10.0
Delay disc. indifference point, 0s delay0.60.71.41.11.11.11.2-1.0-0.90.9-0.70.71.0-1.00.8-0.0-0.40.0-0.8-0.30.9
Delay disc. indifference point, 16s delay0.70.91.51.11.11.11.1-1.0-1.01.0-1.11.10.9-1.20.80.9-1.0-1.0-0.5-0.60.8
Delay disc. indifference point, 2s delay0.10.20.50.70.70.60.6-0.4-0.40.4-0.10.10.3-0.60.2-0.2-0.10.3-0.10.30.1
Delay disc. indifference point, 24s delay0.50.81.11.01.01.01.0-1.0-0.90.9-0.90.90.9-1.00.90.8-0.8-1.0-0.9-0.50.4
Delay disc. indifference point, 4s delay0.10.10.30.60.60.50.5-0.3-0.30.3-0.20.20.2-0.30.1-0.0-0.4-0.20.3-0.00.3
Delay disc. indifference point, 8s delay1.52.64.21.81.71.81.8-1.6-1.61.6-1.81.81.6-1.91.50.9-1.3-1.3-1.4-1.12.1
Indifference point function ln k0.72.23.71.91.91.91.8-1.8-1.71.6-1.71.61.6-1.41.40.7-1.1-0.9-1.3-0.70.7
Indifference point function log k0.72.23.71.91.91.91.8-1.8-1.71.6-1.71.61.6-1.41.40.7-1.1-0.9-1.3-0.70.7
Patch foraging total patch changes 0 sec0.31.02.7-1.3-1.2-1.1-1.10.90.9-0.91.5-1.4-0.61.6-0.5-0.41.10.60.10.1-0.6
Patch foraging total patch changes 12 sec0.30.40.9-1.0-0.8-0.7-0.70.50.5-0.50.8-0.7-0.30.9-0.00.50.4-0.2-0.3-0.80.1
Patch foraging total patch changes 18 sec0.81.83.7-1.7-1.6-1.6-1.71.31.3-1.31.9-1.7-1.11.7-0.9-0.60.90.90.70.1-1.5
Patch foraging total patch changes 24 sec0.20.71.7-1.0-1.0-1.0-1.10.90.8-0.81.0-0.9-0.90.9-0.7-0.20.50.30.60.5-1.3
Patch foraging total patch changes 6 sec1.22.04.1-1.7-1.6-1.5-1.51.31.4-1.42.0-1.9-1.12.0-1.0-1.01.51.20.60.5-0.9
Patch foraging time to switch 0 sec1.14.35.3-2.2-2.2-2.3-2.32.32.2-2.22.2-2.2-2.22.0-2.1-1.51.51.32.31.8-1.9
Patch foraging water rate 0 sec2.17.99.52.92.93.03.0-3.0-2.92.9-2.82.72.9-2.72.92.7-2.5-2.4-3.1-2.42.8
Patch foraging water rate 12 sec1.04.05.22.32.22.22.1-2.2-2.22.1-2.22.22.0-2.02.01.8-1.7-1.7-1.9-1.31.6
Patch foraging water rate 18 sec0.30.71.71.11.01.00.9-0.9-0.90.9-1.31.10.7-0.80.70.5-0.5-0.5-0.5-0.00.8
Patch foraging water rate 24 sec4.86.810.22.42.52.62.7-2.7-2.62.7-2.52.42.8-2.22.92.2-2.5-2.2-3.1-2.63.2
Patch foraging water rate 6 sec5.48.09.72.92.93.03.0-3.0-3.03.0-2.62.63.0-2.33.02.7-2.4-2.6-3.1-2.52.8
Seeking ratio, delayed vs. immediate footshock0.00.00.10.20.20.20.2-0.1-0.10.10.2-0.20.10.2-0.0-0.1-0.3-0.0-0.00.20.1
Distance traveled before self-admin0.10.20.7-0.6-0.5-0.4-0.40.30.3-0.30.9-0.8-0.10.5-0.0-0.4-0.00.3-0.4-0.5-0.1
Distance traveled after self-admin0.50.94.00.10.10.30.4-0.4-0.50.6-0.70.60.7-0.80.91.0-1.1-1.1-1.6-1.62.0
Extensor digitorum longus weight5.020.125.05.05.04.94.8-4.7-4.74.7-4.64.64.5-4.64.34.6-4.4-4.3-3.6-3.33.5
Bone: elastic displacement2.12.74.6-2.1-2.1-1.9-1.91.81.8-1.81.9-1.9-1.51.8-1.4-1.41.61.40.70.4-1.1
Bone: elastic work0.10.10.6-0.1-0.1-0.00.1-0.1-0.10.1-0.10.10.3-0.10.30.7-0.2-0.5-0.8-0.70.6
Bone: endosteal estimation6.014.617.44.14.24.14.0-4.0-4.14.0-3.63.73.9-3.73.93.9-3.9-4.0-3.2-3.72.6
Bone: endosteal perimeter5.613.615.93.94.03.93.9-3.9-3.93.9-3.53.53.8-3.63.83.6-3.7-3.8-3.1-3.82.7
Epididymis fat weight0.84.27.62.32.12.02.0-1.9-2.12.0-2.82.71.6-2.31.72.4-2.1-2.1-1.1-1.31.9
Delta time in closed arm before/after self-admin0.10.10.1-0.2-0.2-0.3-0.30.30.2-0.20.1-0.1-0.30.2-0.30.20.10.20.1-0.3-0.3
Delta time in open arm before/after self-admin0.50.61.0-0.8-0.8-0.7-0.70.70.7-0.70.8-0.8-0.70.7-0.7-1.00.81.00.50.5-0.5
Diff in mean of infusions in LGA sessions0.20.30.50.70.70.60.7-0.6-0.50.5-0.70.40.6-0.50.40.5-0.2-0.5-0.4-0.10.3
Delay discount exponential model param0.40.61.1-1.0-0.9-0.9-1.00.80.7-0.80.7-0.7-0.71.0-0.6-0.40.60.60.50.3-0.8
Extinction: sum of active levers before priming1.42.23.81.41.51.51.5-1.6-1.61.6-1.01.11.7-1.31.61.5-1.6-1.2-1.7-2.00.8
Active lever presses in extinction session 61.91.95.41.21.31.41.4-1.5-1.41.4-0.80.91.6-0.81.61.1-0.8-1.1-1.9-2.31.3
Bone: final force8.413.716.24.04.04.04.0-3.9-3.93.9-3.83.83.8-3.83.73.4-3.7-3.5-3.1-3.03.1
Bone: final moment8.814.216.94.14.14.04.0-3.9-3.93.9-3.93.93.8-3.93.73.6-3.8-3.7-3.2-3.13.2
Food consumed during 24 hour testing period0.71.41.81.21.21.11.2-1.1-1.11.1-1.21.21.0-1.21.01.2-1.2-1.3-1.0-1.31.3
Glucose0.10.10.30.40.30.20.2-0.1-0.10.1-0.10.1-0.0-0.2-0.1-0.4-0.10.60.50.4-0.3
Heart weight0.10.10.70.20.20.10.10.20.1-0.1-0.10.1-0.30.1-0.4-0.50.40.20.90.4-0.3
Delay discount hyperbolic model param0.30.40.9-0.9-0.8-0.8-0.90.60.6-0.60.5-0.5-0.60.9-0.4-0.30.50.40.20.1-0.7
Intermittent access intake day 1-15 change0.00.20.9-0.1-0.2-0.2-0.30.40.3-0.40.0-0.2-0.50.3-0.5-0.30.50.51.00.8-0.2
Intermittent access intake escalation0.00.10.50.20.10.10.10.10.0-0.0-0.30.1-0.2-0.1-0.20.00.20.20.70.60.1
Intermittent access intake escalation 20.10.10.60.20.20.20.2-0.2-0.20.2-0.1-0.00.2-0.40.20.8-0.5-0.80.1-0.30.6
Intermitt. access day 1 inactive lever presses0.21.94.0-1.4-1.3-1.4-1.51.31.3-1.31.6-1.8-1.31.6-1.3-1.21.20.81.20.8-2.0
Intermitt. access day 15 inactive lever presses0.31.82.6-1.2-1.2-1.3-1.21.31.4-1.41.2-1.3-1.31.4-1.4-1.61.61.61.40.7-1.1
Intermitt. access escalation Index0.51.43.20.81.01.00.9-1.3-1.21.20.0-0.11.4-0.71.51.6-1.6-1.3-1.8-1.70.0
Intermittent access day 1 total infusions0.41.21.9-1.1-1.1-1.1-1.01.11.1-1.11.2-1.0-1.01.3-1.1-1.31.41.30.70.4-0.7
Intermittent access day 15 total infusions0.30.81.5-0.7-0.8-0.8-0.80.90.9-0.90.7-0.8-0.90.9-1.0-0.81.11.11.21.0-0.9
Intermittent access terminal intake (last 3 days)0.81.52.4-1.1-1.1-1.2-1.21.21.2-1.21.1-1.1-1.31.2-1.4-1.01.31.21.51.4-1.2
Intermittent access total infusions0.70.91.4-1.0-1.0-1.0-1.01.01.0-1.01.0-0.9-0.91.1-0.9-0.81.20.90.80.5-0.7
Intermittent access day 1 locomotion0.10.20.7-0.3-0.3-0.3-0.40.30.3-0.40.2-0.0-0.50.4-0.5-0.60.30.90.50.4-0.6
Intermittent access day 15 total locomotion0.00.10.4-0.2-0.2-0.2-0.30.30.2-0.30.0-0.1-0.40.3-0.4-0.20.30.50.60.3-0.4
Intermittent access total locomotion0.30.30.7-0.6-0.6-0.7-0.70.70.6-0.60.1-0.0-0.80.4-0.7-0.60.40.80.80.3-0.4
Intermittent access standard deviation0.10.51.5-0.6-0.6-0.7-0.70.80.8-0.80.4-0.3-0.90.6-0.9-0.60.90.51.20.5-0.5
Left kidney weight0.42.84.52.12.02.02.1-1.8-1.71.8-1.81.71.7-1.91.51.4-1.3-1.0-1.3-1.41.5
Right kidney weight1.913.019.34.44.34.24.2-4.0-3.93.9-3.73.53.8-3.53.43.1-3.2-2.8-2.8-2.82.4
Cocaine induced anxiety1.43.84.62.12.12.01.9-2.0-2.02.0-2.12.11.8-2.01.91.8-2.0-1.9-1.9-1.81.6
Post-drug Anxiety4.75.37.82.22.22.22.2-2.1-2.32.3-2.32.32.1-2.42.22.7-2.5-2.8-2.3-2.02.4
Baseline Anxiety0.20.30.90.40.40.40.5-0.5-0.50.5-0.40.40.6-0.60.61.0-0.6-0.9-0.4-0.30.8
Tail length0.00.21.80.10.10.0-0.00.10.1-0.20.00.1-0.30.1-0.4-0.70.41.30.50.9-0.7
Length with tail1.04.36.62.62.62.52.5-2.4-2.32.3-2.32.42.2-2.12.01.7-1.3-0.9-1.8-1.41.3
Length without tail3.216.820.74.54.54.54.5-4.3-4.34.3-4.54.44.2-4.14.04.1-3.3-3.7-3.5-3.23.4
Times rat made contact with spout0.10.10.30.40.30.30.4-0.3-0.30.4-0.40.40.3-0.30.30.4-0.5-0.3-0.4-0.10.5
Lifetime Intake0.60.81.4-1.0-1.0-0.9-0.90.90.9-0.91.1-1.0-0.81.1-0.8-0.81.20.90.40.2-0.4
Liver weight, left5.910.212.23.53.53.43.4-3.3-3.33.3-3.33.33.2-3.33.13.1-3.5-2.9-2.7-2.72.5
Liver weight, right2.84.87.52.22.32.32.3-2.4-2.32.3-1.81.82.4-2.02.31.9-2.1-1.9-2.5-2.71.8
Locomotor activity0.81.21.8-1.2-1.2-1.2-1.21.21.1-1.11.4-1.2-1.11.2-1.1-1.10.91.01.10.8-0.9
Locomotor testing distance1.12.64.4-1.9-1.8-1.8-1.81.61.6-1.62.1-1.9-1.51.8-1.4-1.71.21.61.00.5-1.7
Locomotor testing rearing0.72.55.7-1.9-1.7-1.7-1.71.41.5-1.52.4-2.2-1.21.9-1.2-1.41.31.30.70.2-1.9
Locomotion in novel chamber1.11.52.21.41.41.41.5-1.4-1.31.4-1.21.21.4-1.01.30.9-1.0-1.0-1.4-0.70.9
Locomotion in novel chamber post-restriction0.00.10.50.50.40.40.4-0.3-0.40.3-0.30.30.2-0.40.20.2-0.4-0.2-0.10.70.5
Fecal boli incidents, locomotor time 10.20.51.0-0.7-0.9-0.8-0.60.90.9-0.80.2-0.2-0.90.3-0.9-1.00.80.60.60.60.9
Change in fecal boli incidents, locomotor task0.20.32.40.40.50.40.2-0.5-0.40.30.4-0.40.40.50.30.5-0.3-0.1-0.10.1-1.5
Time >=10cm from walls, locomotor time 10.91.13.30.80.81.01.1-1.0-0.91.0-0.80.81.1-1.01.10.6-0.6-0.3-1.6-1.31.8
Bouts of movement, locomotor time 10.20.20.70.30.30.30.3-0.2-0.20.2-0.80.80.2-0.70.1-0.1-0.4-0.2-0.20.70.5
Total resting periods, locomotor time 10.10.10.9-0.2-0.3-0.3-0.20.30.3-0.3-0.20.2-0.4-0.2-0.4-0.60.20.20.41.00.1
Rest time, locomotor task time 10.00.10.3-0.2-0.2-0.2-0.20.10.2-0.10.5-0.5-0.00.3-0.1-0.20.1-0.2-0.10.3-0.5
Distance moved, locomotor task time 10.10.21.1-0.2-0.1-0.00.1-0.0-0.00.1-0.10.10.2-0.10.30.00.00.3-0.7-1.01.0
Vertical activity count, locomotor time 10.31.84.21.21.21.31.4-1.3-1.21.3-1.31.31.4-1.21.41.1-1.0-0.9-1.5-1.62.1
Time >=10cm from walls, locomotor time 20.00.10.7-0.4-0.3-0.2-0.20.20.2-0.10.4-0.40.00.10.1-0.0-0.00.1-0.3-0.90.4
Bouts of movement, locomotor time 21.03.44.92.02.01.91.8-1.9-1.91.9-1.81.81.8-2.11.81.9-2.2-2.1-1.4-1.51.1
Total resting periods, locomotor time 20.83.14.12.02.01.91.8-1.9-1.91.8-1.81.81.7-2.01.61.6-2.0-1.8-1.2-1.20.9
Rest time, locomotor task time 20.10.11.20.20.20.10.0-0.1-0.00.00.3-0.3-0.10.2-0.2-0.20.00.10.41.1-0.9
Distance moved, locomotor task time 20.20.32.0-0.4-0.3-0.1-0.0-0.00.00.1-0.00.00.3-0.30.40.4-0.2-0.6-1.0-1.40.9
Vertical activity count, locomotor time 20.40.91.50.70.70.70.8-0.8-0.80.9-1.01.00.9-1.01.01.0-1.1-1.0-1.1-1.20.8
Light reinforcement 10.94.05.2-2.2-2.2-2.2-2.22.12.0-2.11.9-2.0-2.12.3-2.0-1.81.91.71.71.7-1.9
Light reinforcement 21.32.96.4-1.3-1.4-1.5-1.61.61.5-1.61.1-1.3-1.91.6-1.9-1.81.51.82.12.5-2.0
Bone: marrow area6.014.817.64.14.24.14.0-4.1-4.14.0-3.63.74.0-3.83.93.9-4.0-4.0-3.2-3.72.6
Bone: maximum diameter4.28.410.03.13.23.13.1-3.1-3.13.0-2.82.93.0-2.93.02.7-2.9-2.8-2.5-2.82.0
Bone: maximum force9.618.922.64.84.74.74.7-4.6-4.64.6-4.44.44.4-4.44.34.3-4.3-4.3-3.6-3.53.5
Bone: maximum moment10.119.122.94.84.84.74.7-4.6-4.64.6-4.44.44.4-4.44.34.3-4.3-4.4-3.6-3.63.5
Mean time between licks in bursts0.21.22.9-1.0-1.1-1.1-1.11.21.1-1.10.9-0.9-1.20.9-1.2-1.20.91.20.91.7-0.9
Mean num. licks in bursts0.10.21.40.30.20.20.4-0.1-0.10.2-0.50.50.2-0.40.20.6-0.4-0.60.0-0.31.2
Cd content in liver2.52.84.1-1.2-1.2-1.3-1.41.51.5-1.51.8-1.8-1.61.8-1.7-2.01.91.92.01.8-2.0
Co content in liver0.10.10.4-0.3-0.3-0.3-0.10.40.4-0.30.1-0.1-0.30.1-0.3-0.50.50.40.3-0.30.6
Cu content in liver3.23.96.11.81.91.91.9-2.0-2.02.0-1.71.72.1-1.72.11.8-1.9-2.1-2.3-2.51.8
Fe content in liver1.01.21.6-1.3-1.2-1.2-1.31.11.1-1.11.1-1.1-1.11.1-1.0-1.20.90.80.90.5-1.2
K content in liver0.60.61.01.00.91.01.0-0.9-0.80.8-0.70.70.9-0.70.70.5-0.5-0.5-0.6-0.80.9
Mg content in liver0.10.10.50.10.10.20.2-0.2-0.10.10.3-0.30.30.30.3-0.10.30.1-0.4-0.70.4
Mn content in liver0.10.10.40.10.10.0-0.00.00.1-0.10.1-0.1-0.10.1-0.2-0.10.00.30.60.5-0.6
Na content in liver0.40.52.10.50.60.60.5-0.7-0.70.7-0.20.20.8-0.20.80.8-0.5-0.9-0.9-1.40.0
Rb content in liver0.20.20.60.40.50.50.4-0.6-0.60.5-0.20.20.6-0.20.60.5-0.5-0.3-0.7-0.8-0.1
Se content in liver1.01.22.0-1.0-1.0-1.0-1.01.11.1-1.11.0-1.0-1.11.0-1.1-1.41.11.11.30.9-0.7
Sr content in liver2.32.02.91.41.41.41.4-1.4-1.41.4-1.51.51.4-1.51.41.4-1.4-1.7-1.2-1.41.3
Zn content in liver0.10.20.6-0.3-0.2-0.2-0.20.10.2-0.20.6-0.6-0.00.6-0.1-0.80.50.5-0.2-0.6-0.0
Bone: minimum diameter7.013.415.43.93.93.93.9-3.9-3.83.8-3.53.53.8-3.63.73.5-3.6-3.5-3.4-3.53.0
Time in familiar zone, hab. session 10.10.20.4-0.4-0.4-0.4-0.30.40.5-0.40.4-0.4-0.40.4-0.4-0.50.60.20.50.1-0.1
Time in novel zone, hab. session 10.10.10.30.20.20.20.0-0.2-0.30.2-0.20.20.1-0.20.20.5-0.5-0.1-0.10.0-0.4
Total zone transitions, hab. session 10.40.61.5-0.7-0.7-0.7-0.70.80.8-0.80.4-0.4-0.80.6-0.8-1.20.71.20.70.8-0.1
Total locomotion distance, hab. session 10.10.10.4-0.2-0.3-0.2-0.10.30.3-0.30.1-0.1-0.30.2-0.3-0.60.50.60.3-0.10.5
Locomotion velocity, hab. session 10.10.10.4-0.1-0.1-0.00.00.10.1-0.10.0-0.1-0.10.2-0.1-0.50.40.6-0.1-0.30.7
Time in familiar zone, hab. session 20.10.10.50.10.20.20.2-0.1-0.10.20.2-0.20.20.10.20.60.0-0.70.3-0.3-0.0
Time in novel zone, hab. session 20.10.10.4-0.1-0.2-0.2-0.30.20.2-0.2-0.10.1-0.4-0.0-0.3-0.4-0.10.60.10.4-0.5
Total zone transitions, hab. session 20.20.20.9-0.3-0.3-0.3-0.20.40.4-0.40.2-0.2-0.30.3-0.4-1.00.60.90.20.40.2
Total locomotion distance, hab. session 20.20.30.9-0.5-0.5-0.4-0.30.50.5-0.50.6-0.6-0.40.7-0.4-0.81.01.00.10.10.1
Locomotion velocity, hab. session 20.10.20.8-0.2-0.2-0.2-0.10.20.3-0.30.3-0.4-0.10.4-0.2-0.80.80.9-0.10.00.3
Novel to familiar place preference ratio0.40.60.90.90.90.90.7-0.9-0.90.8-0.60.60.8-0.50.71.0-0.7-0.9-0.6-0.6-0.1
Novelty place preference0.20.20.50.60.60.50.4-0.6-0.60.5-0.30.30.4-0.20.40.7-0.5-0.6-0.3-0.3-0.5
Time in novel zone, NPP test0.10.20.40.50.50.40.3-0.4-0.50.4-0.20.20.3-0.10.30.6-0.4-0.5-0.1-0.3-0.6
Total zone transitions, NPP test1.01.43.8-1.2-1.2-1.1-1.01.21.3-1.20.8-0.8-1.11.0-1.1-1.91.41.80.71.30.1
Total locomotion distance, NPP test2.53.56.1-1.9-1.9-1.8-1.71.92.0-1.91.8-1.8-1.82.0-1.8-2.42.32.51.21.6-0.7
Locomotion velocity, NPP test1.52.24.4-1.4-1.5-1.4-1.21.51.5-1.51.4-1.4-1.31.5-1.4-2.01.92.10.81.4-0.3
Intraocular pressure5.18.312.9-3.6-3.5-3.4-3.33.33.2-3.13.0-2.9-3.03.0-2.7-2.62.72.02.21.8-1.4
Delta distance traveled before/after self-admin0.30.31.40.30.20.30.3-0.3-0.40.4-0.90.80.3-0.50.50.6-0.1-0.6-0.9-0.51.2
Delta ambulatory time before/after self-admin0.20.31.30.20.10.20.2-0.2-0.30.3-0.90.80.2-0.50.40.6-0.3-0.6-0.8-0.31.1
Parametrial fat weight0.10.21.2-0.6-0.6-0.5-0.40.50.4-0.4-0.20.1-0.4-0.0-0.2-0.20.4-0.3-0.1-0.61.1
Pavlov. Cond. lever latency0.10.20.90.30.40.40.3-0.5-0.40.40.1-0.10.60.20.60.2-0.0-0.3-0.6-1.0-0.2
Pavlov. Cond. magazine entry latency0.00.10.1-0.3-0.3-0.3-0.20.30.3-0.20.0-0.0-0.2-0.1-0.20.30.0-0.30.3-0.20.4
Pavlov. Cond. change in total contacts0.10.10.7-0.1-0.2-0.3-0.30.40.3-0.30.2-0.2-0.50.0-0.5-0.20.20.10.80.6-0.3
Pavlov. Cond. index score0.10.20.60.30.20.20.3-0.2-0.30.3-0.60.60.2-0.80.20.5-0.6-0.6-0.1-0.10.6
Pavlov. Cond. latency score0.10.10.40.20.10.10.10.0-0.10.1-0.50.5-0.1-0.7-0.00.4-0.4-0.40.10.20.6
Pavlov. Cond. lever contacts0.50.71.9-0.7-0.8-0.9-0.81.00.8-0.90.5-0.4-1.00.2-1.0-0.60.50.71.01.4-0.3
Pavlov. Cond. magazine entry number0.10.10.5-0.0-0.0-0.1-0.10.00.1-0.10.4-0.4-0.10.5-0.1-0.50.30.60.10.5-0.7
Pavlov. Cond. intertrial magazine entries0.80.91.2-0.8-0.8-0.9-0.81.01.0-1.01.0-1.0-1.01.1-1.0-1.01.11.01.10.7-0.7
Pavlov. Cond. lever-magazine prob. diff.0.40.51.10.60.60.60.6-0.5-0.60.6-0.90.90.5-1.10.50.8-0.9-0.9-0.4-0.40.8
Pavlov. Cond. response bias0.10.10.2-0.4-0.4-0.4-0.30.50.4-0.40.0-0.1-0.4-0.1-0.40.10.1-0.00.40.30.2
Pavlov. Cond. lever latency0.10.10.60.30.30.20.1-0.1-0.10.1-0.10.00.0-0.1-0.1-0.60.00.50.20.6-0.8
Pavlov. Cond. magazine entry latency0.20.30.80.40.50.50.5-0.5-0.50.5-0.20.20.6-0.20.50.7-0.3-0.5-0.7-0.90.5
Pavlov. Cond. change in total contacts0.61.52.61.21.21.21.2-1.2-1.21.2-1.11.11.2-1.01.21.6-1.2-1.5-1.0-1.31.4
Pavlov. Cond. index score0.50.81.90.60.60.70.8-0.8-0.80.8-0.50.60.9-0.50.91.1-0.6-1.0-1.2-1.41.3
Pavlov. Cond. latency score0.50.71.70.60.60.70.8-0.8-0.80.8-0.50.50.9-0.50.91.1-0.6-1.0-1.2-1.31.3
Pavlov. Cond. lever contacts0.10.21.0-0.1-0.10.00.1-0.1-0.10.1-0.00.00.20.00.30.7-0.1-0.6-0.5-0.91.0
Pavlov. Cond. magazine entry number1.01.31.7-1.2-1.2-1.2-1.21.21.2-1.20.9-0.9-1.20.9-1.2-1.31.01.11.21.3-0.9
Pavlov. Cond. intertrial magazine entries1.22.73.8-1.9-1.9-1.9-1.81.81.8-1.81.5-1.5-1.71.5-1.6-1.91.61.61.11.2-0.7
Pavlov. Cond. lever-magazine prob. diff.0.61.02.10.70.70.90.9-0.9-0.90.9-0.70.71.0-0.61.11.2-0.8-1.1-1.3-1.51.4
Pavlov. Cond. response bias0.10.20.80.10.10.10.2-0.2-0.20.2-0.10.10.3-0.10.40.7-0.2-0.6-0.5-0.90.8
Time in closed arm before self-admin0.30.61.21.11.11.11.1-0.9-0.80.8-1.01.00.8-0.60.6-0.20.10.2-0.4-0.10.4
Time in closed arm after self-admin0.20.21.2-0.1-0.0-0.1-0.10.00.2-0.20.3-0.4-0.00.5-0.1-0.60.61.1-0.2-0.2-0.8
Time in open arm before self-admin0.10.11.5-0.1-0.0-0.1-0.30.10.0-0.10.4-0.4-0.20.4-0.10.3-0.1-0.40.40.0-1.2
Time in open arm after self-admin0.20.20.7-0.2-0.2-0.3-0.40.30.3-0.30.0-0.0-0.50.2-0.5-0.40.00.10.80.6-0.8
Bone: periosteal estimation10.023.727.45.25.25.25.1-5.1-5.15.1-4.84.85.0-4.84.94.6-4.9-4.7-4.3-4.63.8
Bone: periosteal perimeter9.418.521.04.54.64.64.6-4.5-4.44.5-4.24.24.5-4.24.44.1-4.1-4.2-3.9-4.23.6
Bone: post-yield work6.310.913.03.63.63.53.4-3.4-3.53.4-3.53.63.2-3.63.23.5-3.6-3.3-2.4-2.32.3
Progressive ratio test 1 active lever presses1.32.23.3-1.8-1.8-1.7-1.61.61.6-1.61.6-1.5-1.51.5-1.4-1.81.41.70.80.5-0.4
Progressive ratio test 1 breakpoint1.11.92.9-1.7-1.7-1.5-1.51.51.5-1.51.4-1.3-1.41.4-1.2-1.71.31.60.70.4-0.3
Progressive ratio test 1 inactive lever presses0.61.62.9-1.2-1.1-1.1-1.21.11.2-1.21.7-1.7-1.11.5-1.2-1.21.41.11.10.0-1.6
Progressive ratio test 2 active lever presses0.60.81.6-1.0-0.9-0.9-1.00.80.8-0.91.3-1.2-0.81.2-0.8-0.80.80.70.70.3-1.2
Progressive ratio test 2 breakpoint0.70.91.7-0.9-0.9-0.9-1.00.80.8-0.91.3-1.2-0.81.1-0.8-0.80.80.70.80.3-1.3
Progressive ratio test 2 inactive lever presses0.41.22.7-1.1-1.1-1.0-1.11.01.0-1.01.6-1.7-0.91.5-0.9-1.01.10.70.70.1-1.2
Incentive Sensitization - Responses0.10.31.00.50.60.50.4-0.6-0.60.50.3-0.20.60.00.40.5-0.3-0.6-0.1-0.5-1.0
Incentive Sensitization - Breakpoint0.10.21.50.40.50.40.2-0.5-0.40.40.5-0.40.40.10.30.4-0.3-0.60.0-0.4-1.2
Sum of active levers in priming session hrs 5-60.10.10.4-0.2-0.1-0.2-0.20.10.1-0.10.1-0.0-0.1-0.0-0.00.2-0.4-0.2-0.00.3-0.7
Progressive ratio0.00.10.4-0.2-0.1-0.0-0.0-0.00.1-0.00.4-0.40.20.60.2-0.20.10.2-0.5-0.10.2
Food seeking constrained by brief footshock0.81.03.40.30.30.50.5-0.6-0.70.7-0.50.50.8-0.81.11.6-0.8-1.3-1.5-1.81.7
Seeking ratio, punishment vs. effort0.10.10.60.10.10.10.0-0.1-0.20.2-0.40.40.0-0.80.10.6-0.4-0.50.0-0.50.3
Retroperitoneal fat weight0.10.51.8-0.4-0.5-0.6-0.70.80.6-0.6-0.30.3-1.00.0-0.9-0.40.50.31.31.1-0.4
Reaction time number correct0.31.01.30.90.90.90.9-0.9-1.01.0-1.11.10.9-1.11.01.0-0.8-1.0-1.1-0.71.0
Reaction time mean minus median2.012.717.4-3.7-3.7-3.8-3.63.93.9-3.83.6-3.4-3.83.2-3.8-3.22.93.14.23.2-3.0
Reaction time mean minus median AUC1.38.411.6-3.0-3.1-3.2-3.03.23.2-3.12.9-2.8-3.12.6-3.2-2.42.22.43.42.8-2.4
Reaction time num false alarms1.11.93.8-1.5-1.4-1.3-1.21.31.4-1.31.7-1.7-1.11.4-1.1-1.71.91.80.60.9-0.6
Reaction time num false alarms AUC1.33.05.1-1.9-1.9-1.7-1.61.71.8-1.72.2-2.1-1.41.8-1.4-1.92.32.00.91.1-0.7
Reaction time trials correct on left0.31.01.30.90.90.90.9-0.9-1.01.0-1.11.10.9-1.11.01.0-0.8-1.0-1.1-0.71.0
Reaction time trials on left0.20.71.00.70.70.80.7-0.8-0.90.8-0.91.00.8-1.00.90.9-0.7-0.9-1.0-0.60.9
Reaction time mean0.40.92.3-1.0-1.1-1.1-1.01.21.1-1.00.9-0.8-1.20.3-1.2-0.40.10.21.51.1-0.5
Reaction time mean AUC0.20.41.2-0.7-0.8-0.8-0.70.80.8-0.70.6-0.5-0.8-0.0-0.8-0.1-0.2-0.21.10.8-0.1
Median of all reaction times0.10.21.00.20.10.10.1-0.0-0.10.2-0.30.30.0-0.90.00.7-1.0-0.90.20.00.6
Reaction time omissions5.89.412.7-3.6-3.5-3.5-3.33.53.5-3.33.3-3.1-3.22.8-3.2-2.42.42.23.32.2-2.2
Reaction time false alarm rate1.92.64.1-1.7-1.7-1.6-1.41.51.7-1.62.0-2.0-1.31.7-1.4-1.82.01.91.01.1-0.8
Reaction time premature initiation rate1.21.83.3-1.8-1.8-1.7-1.61.61.5-1.51.1-1.0-1.41.2-1.2-1.21.41.10.90.7-0.5
Reaction time premature initiations0.30.81.8-1.3-1.3-1.2-1.21.11.0-1.00.6-0.5-1.00.7-0.8-0.60.90.50.50.4-0.2
Std. dev. reaction times2.89.414.1-3.2-3.2-3.3-3.23.43.4-3.33.1-2.9-3.42.5-3.4-2.52.22.43.82.9-2.6
Reaction time trials completed0.20.71.00.70.70.80.7-0.8-0.90.8-0.91.00.8-1.00.90.9-0.7-0.9-1.0-0.60.9
Reaction time trials AUC0.41.31.71.11.11.11.0-1.1-1.21.2-1.31.31.1-1.31.21.2-0.9-1.2-1.3-0.91.2
Run reversals in cocaine runway, females0.30.41.3-0.6-0.4-0.4-0.40.20.4-0.41.0-1.0-0.11.1-0.1-0.90.50.9-0.4-0.2-0.8
Run reversals in cocaine runway, males1.61.84.9-1.0-1.2-1.2-1.11.31.4-1.30.9-0.9-1.41.1-1.5-1.41.32.01.52.2-0.6
Latency to leave start box in cocaine runway0.10.20.9-0.2-0.3-0.3-0.40.40.4-0.4-0.0-0.1-0.50.0-0.5-0.40.10.70.71.0-0.5
Latency to leave start box in cocaine runway, F1.01.21.5-1.2-1.1-1.2-1.21.11.2-1.11.1-1.2-1.10.9-1.1-1.10.81.21.11.1-1.1
Latency to leave start box in cocaine runway, M1.51.52.31.41.31.31.2-1.2-1.31.3-1.51.51.1-1.41.11.1-1.3-0.8-0.8-0.60.9
Std. dev. time between licks in bursts0.30.51.0-1.0-1.0-1.0-0.90.90.8-0.80.6-0.6-0.90.6-0.7-0.40.40.40.40.4-0.3
Total sessions with >9 infusions0.70.82.4-0.8-0.8-0.7-0.60.80.9-0.80.9-0.8-0.71.2-0.8-1.41.51.40.50.2-0.2
Short access day 1 total inactive lever presses0.50.91.8-1.1-1.1-1.0-0.91.01.0-1.01.1-1.3-0.81.2-0.8-1.11.31.00.30.1-0.2
Short access day 10 total inactive lever presses0.00.10.8-0.3-0.3-0.2-0.20.20.2-0.20.5-0.6-0.10.3-0.00.10.1-0.20.0-0.90.0
Short access day 1 total infusions0.10.20.6-0.4-0.3-0.2-0.20.20.4-0.30.7-0.6-0.10.7-0.2-0.60.80.6-0.10.1-0.2
Short access day 10 total infusions1.01.74.4-1.0-1.1-1.0-1.01.21.3-1.31.0-0.9-1.21.4-1.3-2.02.11.91.01.2-0.6
Short access total infusions0.60.81.7-1.0-1.0-0.9-0.90.90.9-0.91.1-1.0-0.71.2-0.7-1.01.31.10.30.2-0.5
Short access day 1 locomotion0.20.31.1-0.0-0.0-0.0-0.10.20.3-0.30.10.0-0.30.4-0.4-1.11.01.10.50.6-0.3
Short access day 10 total locomotion0.20.82.7-0.5-0.6-0.6-0.70.80.8-0.80.10.1-1.00.7-1.1-1.51.11.61.10.7-0.4
Short access total locomotion0.50.72.6-0.6-0.6-0.6-0.60.80.8-0.80.10.0-0.90.7-0.9-1.41.21.60.80.6-0.1
One hour access (0.3 mA shock)0.10.10.7-0.1-0.1-0.2-0.20.20.2-0.20.8-0.8-0.10.4-0.3-0.00.2-0.20.5-0.3-0.7
Compulsive drug intake0.20.20.4-0.4-0.4-0.4-0.50.40.4-0.50.6-0.5-0.50.6-0.5-0.40.60.40.40.7-0.6
One hour access (shock baseline)0.00.10.20.40.40.30.3-0.3-0.30.3-0.10.10.3-0.20.10.3-0.3-0.30.2-0.3-0.3
Social response proportion0.81.12.9-0.8-0.8-0.8-0.80.80.9-0.91.4-1.5-0.71.7-0.9-0.81.30.80.80.9-1.2
Social responses7.69.914.2-3.3-3.2-3.2-3.13.13.2-3.13.8-3.8-2.93.8-2.9-2.73.32.72.82.4-3.1
Social time1.42.24.6-1.1-1.2-1.3-1.41.41.4-1.41.6-1.5-1.61.2-1.7-1.21.21.12.11.6-2.1
Soleus weight0.92.53.91.81.81.71.7-1.6-1.71.7-1.91.91.5-2.01.41.1-1.8-1.2-1.0-0.91.4
Bone: stiffness11.120.124.85.05.04.94.8-4.8-4.74.7-4.54.54.6-4.54.44.5-4.4-4.5-3.5-3.63.4
Tibialis anterior weight2.06.88.83.02.92.92.9-2.8-2.82.8-2.72.72.6-2.72.52.4-2.5-2.4-2.1-1.82.0
Time to tail flick, vehicle, before self-admin0.70.93.0-1.3-1.2-1.1-1.01.01.0-0.91.7-1.6-0.70.9-0.6-0.10.40.20.4-0.3-0.3
Time to tail flick, vehicle, after self-admin0.10.21.1-0.3-0.3-0.3-0.30.30.3-0.30.5-0.5-0.30.5-0.4-0.10.40.20.50.1-1.1
Time to tail flick, test, before self-admin0.80.93.1-0.8-0.7-0.7-0.70.60.8-0.71.7-1.7-0.51.2-0.7-0.51.00.50.40.6-1.3
Time to tail flick, test, after self-admin0.30.33.50.20.30.1-0.0-0.10.0-0.10.5-0.8-0.10.2-0.3-0.20.10.20.50.6-1.9
Delta time to tail flick, vehicle, before/after SA0.20.20.40.50.50.40.3-0.4-0.40.4-0.60.60.3-0.40.30.5-0.3-0.6-0.2-0.4-0.1
Delta time to tail flick, test, before/after SA0.20.31.20.30.30.1-0.00.00.0-0.1-0.60.5-0.3-0.3-0.4-0.5-0.10.60.91.1-1.1
Tibia length6.718.721.94.34.44.44.4-4.6-4.54.5-3.93.94.6-4.04.74.5-4.3-4.4-4.5-4.53.3
Ambulatory time before self-admin0.31.02.3-1.2-1.2-1.0-1.00.91.0-1.01.5-1.5-0.71.2-0.6-1.20.81.10.1-0.1-0.4
Ambulatory time after self-admin0.40.63.1-0.4-0.3-0.1-0.0-0.1-0.20.2-0.20.10.4-0.30.70.6-0.7-0.6-1.5-1.71.7
Bone: tissue strength0.20.30.70.60.50.40.4-0.4-0.50.5-0.60.60.3-0.60.30.9-0.8-0.7-0.10.3-0.0
Total heroin consumption1.82.13.71.31.41.41.3-1.5-1.51.5-1.41.31.5-1.21.61.5-1.2-1.5-1.7-1.91.1
Bone: trabecular number3.66.77.72.62.62.72.8-2.6-2.62.7-2.62.62.7-2.62.62.7-2.4-2.7-2.4-2.22.6
Bone: trabecular spacing1.21.83.2-1.3-1.2-1.3-1.41.21.2-1.31.0-1.0-1.41.0-1.3-1.70.91.61.41.6-1.8
Bone: trabecular thickness0.20.30.8-0.6-0.5-0.5-0.40.60.6-0.50.8-0.8-0.40.8-0.5-0.30.90.30.30.1-0.1
Bone: trabecular tissue density0.30.51.4-0.4-0.5-0.5-0.60.60.6-0.60.4-0.4-0.80.5-0.8-0.80.50.90.91.2-0.7
Water consumed over 24 hours0.20.41.20.70.60.50.5-0.4-0.50.5-0.80.80.3-0.80.31.1-0.9-0.9-0.0-0.10.4
Number of responses in last shaping day0.40.51.70.0-0.0-0.1-0.20.40.4-0.40.1-0.1-0.60.6-0.8-1.21.31.01.00.9-0.7