Hub : Genes

Alk

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Alk 0.25 0.13 1.9e-14 0.13 0.12 0.12 0.12 1.5e-14 1.1e-13 1.4e-13 1.0e-13
2 NAcc alternative polyA XM_039111819.1 0.17 0.07 1.2e-09 0.08 0.06 0.07 0.08 1.1e-09 5.5e-08 3.6e-08 1.5e-09
3 Brain mRNA stability Alk 0.07 0.05 1.8e-03 0.02 0.01 0.02 0.01 2.9e-03 2.7e-02 1.1e-02 1.4e-02
4 PL isoform ratio NM_001169101.3 0.06 0.05 4.9e-05 0.03 0.03 0.03 0.03 1.0e-04 5.5e-04 1.7e-04 4.3e-04
5 PL isoform ratio XM_039111819.1 0.14 0.09 1.2e-05 0.04 0.03 0.04 0.04 2.3e-05 1.1e-04 7.0e-05 9.6e-05
6 NAcc alternative polyA NM_001169101.3 0.18 0.07 1.1e-11 0.09 0.09 0.09 0.1 5.5e-11 9.6e-11 6.1e-11 1.3e-11
7 IL alternative TSS XM_039111819.1 0.58 0.21 8.9e-04 0.04 0.05 0.03 0.02 3.9e-02 2.6e-02 6.4e-02 9.1e-02
8 PL mRNA stability Alk 0.09 0.05 1.2e-09 0.06 0.08 0.07 0.08 1.9e-07 8.6e-09 2.4e-08 4.2e-09
9 IL alternative TSS NM_001169101.3 0.57 0.22 1.8e-03 0.03 0.04 -0.01 0.01 7.4e-02 5.1e-02 8.2e-01 1.7e-01
10 NAcc isoform ratio XM_039111819.1 0.07 0.04 1.3e-05 0.04 0.03 0.03 0.03 3.3e-05 3.7e-04 2.0e-04 2.3e-04
11 NAcc gene expression Alk 0.17 0.07 0.0e+00 0.23 0.23 0.23 0.23 5.8e-26 1.8e-26 2.6e-26 2.3e-26
12 PL gene expression Alk 0.07 0.05 1.2e-07 0.05 0.05 0.04 0.05 3.6e-06 1.3e-06 2.4e-05 8.0e-06
13 NAcc isoform ratio NM_001169101.3 0.04 0.04 7.9e-05 0.01 0.02 0.02 0.02 1.9e-02 1.8e-03 2.2e-03 3.9e-03
14 Brain alternative polyA XM_039111819.1 0.07 0.05 5.7e-05 0.01 0.04 0.03 0.02 3.8e-02 2.1e-04 5.8e-04 3.9e-03
15 Brain alternative polyA NM_001169101.3 0.07 0.04 6.5e-05 0.01 0.04 0.03 0.02 2.6e-02 2.7e-04 1.1e-03 5.8e-03
16 pVTA isoform ratio XM_039111819.1 0.19 0.1 5.1e-08 0.12 0.17 0.15 0.14 5.5e-06 7.6e-08 6.6e-07 1.5e-06
17 OFC gene expression Alk 0.17 0.12 3.8e-03 0.07 0.09 0.05 0.1 8.0e-03 4.5e-03 3.1e-02 2.4e-03
18 pVTA isoform ratio NM_001169101.3 0.16 0.11 8.7e-06 0.06 0.11 0.08 0.08 1.7e-03 1.7e-05 1.7e-04 3.6e-04
19 Brain isoform ratio NM_001169101.3 0.08 0.07 3.9e-03 -0 0.01 0.01 0.01 3.8e-01 5.1e-02 8.6e-02 5.4e-02
20 Brain isoform ratio XM_039111819.1 0.18 0.09 4.1e-06 0.01 0.05 0.04 0.05 2.1e-02 2.5e-05 4.4e-05 3.5e-05
21 pVTA alternative polyA NM_001169101.3 0.09 0.07 1.6e-03 0.02 0.04 0.04 0.03 4.7e-02 1.1e-02 5.0e-03 2.3e-02
22 pVTA alternative polyA XM_039111819.1 0.1 0.08 4.7e-04 0.03 0.05 0.07 0.04 2.4e-02 4.0e-03 6.6e-04 8.9e-03
23 Brain gene expression Alk 0.15 0.08 6.5e-06 0.01 0.07 0.07 0.06 1.4e-02 9.2e-07 4.6e-07 1.3e-06
24 pVTA mRNA stability Alk 0.05 0.04 8.0e-03 0.06 0.04 0.03 0.04 1.4e-03 8.1e-03 1.6e-02 7.5e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density3.45.613.3-3.4-3.43.13.2-3.2-2.7-3.62.63.6-2.7-2.4-1.8-1.81.6-1.61.7-1.6-1.5-1.51.71.1-0.80.5-0.3
Area under the delay curve1.41.42.2-1.5-1.51.21.4-1.4-1.4-1.31.11.3-1.1-1.2-1.0-1.11.1-1.11.1-0.7-1.1-1.11.51.2-1.21.20.5
BMI with tail0.31.02.91.41.4-1.4-1.21.21.11.7-1.0-1.71.31.00.80.6-0.60.6-0.60.40.50.5-0.5-0.50.3-0.30.4
BMI without tail0.10.11.00.50.4-0.4-0.40.40.20.5-0.0-0.50.20.0-0.1-0.10.2-0.20.1-0.2-0.2-0.20.10.1-0.20.31.0
Body weight0.72.810.82.52.5-2.4-2.42.42.13.2-1.7-3.31.71.30.70.7-0.50.5-0.60.40.40.3-0.70.0-0.40.31.4
Weight adjusted by age0.10.10.30.40.4-0.3-0.20.20.20.3-0.3-0.30.20.20.10.1-0.20.2-0.10.4-0.00.1-0.20.2-0.30.00.5
Bone surface1.42.55.8-2.4-2.42.22.0-2.0-1.8-2.31.92.3-1.9-1.6-1.3-1.31.1-1.11.2-1.3-1.1-1.00.90.5-0.30.1-0.2
Bone volume1.83.17.4-2.6-2.62.32.4-2.4-2.0-2.72.02.7-2.0-1.7-1.3-1.31.2-1.21.2-1.3-1.0-1.01.00.4-0.20.1-0.4
Breakpoint value in progressive ratio session0.80.91.5-1.1-1.11.21.0-1.0-0.9-0.50.90.5-0.7-1.0-1.0-1.21.0-1.01.1-1.1-1.2-1.10.80.5-0.50.90.6
Number of licking bursts0.91.02.2-0.8-0.70.60.9-0.9-0.8-0.10.80.1-0.6-1.0-1.0-1.21.2-1.21.1-1.2-1.1-1.31.21.3-1.41.51.0
Context. condit. distance diff. score0.30.31.21.11.1-1.0-0.60.60.60.9-0.6-1.00.50.40.30.2-0.20.2-0.20.20.10.1-0.30.1-0.20.00.2
Locomotion velocity, session 10.20.20.80.10.0-0.30.1-0.10.3-0.2-0.20.2-0.00.30.30.4-0.50.5-0.40.40.40.5-0.7-0.90.9-0.9-0.4
Locomotion distance, session 11.31.74.8-1.8-1.81.71.6-1.6-1.6-2.21.42.2-1.5-1.2-0.9-0.80.8-0.80.7-0.6-0.6-0.71.20.9-0.70.8-0.1
Locomotion velocity, session 20.00.00.3-0.1-0.1-0.1-0.10.1-0.1-0.50.20.5-0.4-0.1-0.10.1-0.00.0-0.00.30.10.10.00.00.0-0.2-0.4
Locomotion distance, session 20.20.20.9-0.7-0.70.60.3-0.3-0.5-0.90.51.0-0.7-0.4-0.2-0.10.1-0.10.10.2-0.1-0.10.40.4-0.30.1-0.3
Locomotion velocity, session 30.80.92.0-1.0-1.01.10.6-0.6-1.0-1.21.31.2-1.4-1.1-1.1-0.90.9-0.91.0-0.5-1.0-0.90.80.9-0.80.30.6
Locomotion distance, session 32.52.73.6-1.5-1.51.71.3-1.3-1.7-1.11.91.0-1.7-1.8-1.9-1.81.9-1.91.9-1.6-1.8-1.91.61.7-1.71.41.3
Stereotopy head waving bouts, day 31.01.11.7-1.3-1.31.21.2-1.2-1.1-0.81.20.8-1.2-1.2-1.2-1.21.1-1.11.2-1.2-1.2-1.10.70.8-0.80.50.8
Stereotopy head waving duration, day 30.00.00.1-0.3-0.30.10.0-0.0-0.1-0.30.20.3-0.3-0.1-0.1-0.0-0.00.00.00.1-0.00.1-0.2-0.10.2-0.20.1
Locomotion velocity, session 72.02.24.5-1.1-1.11.00.7-0.7-1.4-1.01.51.0-1.7-1.6-1.7-1.41.6-1.61.6-1.0-1.6-1.71.72.1-2.11.81.7
Locomotion distance, session 70.10.21.0-0.0-0.1-0.1-0.10.1-0.2-0.00.10.0-0.2-0.2-0.2-0.10.3-0.30.20.0-0.2-0.30.71.0-1.00.90.1
Stereotopy head waving bouts, day 70.00.00.2-0.3-0.20.2-0.10.1-0.2-0.30.40.3-0.1-0.1-0.1-0.00.0-0.00.00.20.0-0.0-0.0-0.20.2-0.4-0.4
Stereotopy head waving duration, day 70.60.72.2-1.1-1.01.10.7-0.7-1.1-1.51.31.5-1.1-0.9-0.8-0.60.6-0.60.6-0.3-0.5-0.50.40.2-0.1-0.3-0.2
Locomotion velocity, session 80.20.20.7-0.5-0.50.20.3-0.3-0.4-0.60.60.6-0.9-0.6-0.6-0.40.4-0.40.5-0.3-0.5-0.30.00.3-0.3-0.30.4
Locomotion distance, session 80.20.31.4-0.1-0.1-0.00.2-0.2-0.5-0.20.40.2-0.6-0.5-0.6-0.50.6-0.60.6-0.2-0.6-0.60.81.2-1.20.80.3
Degree of sensitization distance1.71.73.01.51.4-1.7-1.41.41.41.3-1.7-1.21.41.51.41.4-1.31.3-1.41.41.41.3-0.8-0.60.6-0.4-0.9
Degree of sensitization stereotypy0.10.10.2-0.3-0.20.3-0.20.2-0.4-0.30.40.3-0.2-0.2-0.2-0.10.2-0.20.10.1-0.1-0.20.50.2-0.20.1-0.4
Conditioned locomotion1.11.33.2-1.1-1.11.31.3-1.3-1.4-1.81.21.8-1.5-1.2-1.0-0.80.9-0.90.9-0.3-0.8-0.91.51.2-1.10.70.1
Cocaine response after cond. corrected1.51.64.8-1.8-1.81.52.0-2.0-1.5-2.21.32.2-1.5-1.2-0.8-0.80.8-0.80.7-0.8-0.5-0.61.00.4-0.20.2-0.6
Cocaine response after cond. not corrected1.51.74.1-1.8-1.81.71.9-1.9-1.5-2.01.42.0-1.5-1.3-1.0-0.90.9-0.90.9-0.9-0.8-0.81.10.6-0.40.4-0.0
Cocaine response before conditioning0.40.52.4-0.4-0.40.80.1-0.1-0.50.10.7-0.2-0.5-0.7-0.9-0.90.8-0.81.0-0.9-1.0-0.90.30.7-0.80.61.6
Saline control response2.12.84.0-1.4-1.41.71.6-1.6-1.6-1.22.01.2-1.8-1.9-2.0-1.91.8-1.81.9-1.9-1.9-1.71.01.5-1.51.11.9
Bone: connectivity density3.35.211.7-3.4-3.43.13.1-3.1-2.6-3.42.43.4-2.5-2.2-1.7-1.81.6-1.61.6-1.6-1.5-1.41.71.1-0.90.7-0.2
Bone: cortical apparent density0.20.21.1-0.6-0.70.91.1-1.1-0.3-0.50.20.5-0.1-0.3-0.1-0.40.1-0.10.2-0.3-0.2-0.1-0.2-0.50.6-0.10.2
Bone: cortical area0.20.30.8-0.6-0.60.10.5-0.5-0.5-0.30.50.2-0.6-0.6-0.6-0.60.7-0.70.6-0.9-0.6-0.70.60.5-0.50.50.3
Bone: cortical porosity0.91.05.3-1.2-1.01.01.0-1.0-1.0-2.20.62.3-0.9-0.30.20.4-0.20.2-0.40.50.60.40.80.10.2-0.2-2.1
Bone: cortical porosity0.91.05.1-1.2-1.11.01.0-1.0-1.0-2.20.72.3-0.8-0.40.20.3-0.10.2-0.40.30.60.30.80.10.2-0.1-2.1
Bone: cortical thickness0.10.21.00.60.6-1.0-0.30.30.50.5-0.6-0.50.50.50.50.4-0.40.4-0.50.20.50.4-0.2-0.50.5-0.3-0.6
Bone: cortical thickness0.30.31.2-0.8-0.70.60.9-0.9-0.6-1.10.31.1-0.6-0.4-0.1-0.10.2-0.20.1-0.1-0.0-0.20.80.4-0.30.5-0.7
Bone: cortical tissue density0.10.20.9-0.5-0.60.80.9-0.9-0.2-0.40.10.40.1-0.10.0-0.2-0.00.00.1-0.2-0.10.0-0.4-0.70.7-0.20.2
Condit. Reinf. active minus inactive responses0.00.00.4-0.2-0.20.2-0.20.20.10.3-0.1-0.30.40.10.1-0.00.1-0.1-0.00.1-0.0-0.10.10.0-0.10.70.4
Condit. Reinf. active-inactive response ratio0.10.10.3-0.3-0.20.2-0.10.1-0.1-0.20.40.2-0.3-0.3-0.4-0.30.3-0.30.3-0.1-0.3-0.2-0.10.0-0.00.10.5
Condit. Reinf. active responses0.81.02.5-1.4-1.41.21.0-1.0-1.0-0.80.70.8-0.5-0.8-0.7-0.80.9-0.90.7-0.7-0.7-0.91.31.1-1.01.60.5
Condit. Reinf. inactive responses0.70.82.2-1.4-1.31.11.5-1.5-1.0-1.10.41.2-0.4-0.6-0.2-0.40.5-0.50.3-0.5-0.2-0.41.30.8-0.71.1-0.4
Incentive salience index mean0.91.12.2-1.5-1.41.40.8-0.8-1.2-1.11.11.1-0.9-1.0-0.9-0.91.0-1.00.9-0.7-0.8-0.91.21.0-1.01.30.6
Condit. Reinf. lever presses2.43.35.5-2.2-2.22.31.5-1.5-2.2-2.32.12.3-2.0-1.8-1.6-1.41.6-1.61.4-1.0-1.3-1.52.21.9-1.71.70.5
Condit. Reinf. active minus inactive responses1.21.52.9-1.2-1.20.81.7-1.7-1.3-1.00.91.0-1.1-1.2-1.0-1.11.3-1.21.0-1.2-0.9-1.21.61.5-1.41.70.5
Condit. Reinf. active-inactive response ratio0.40.41.1-0.5-0.50.40.6-0.6-0.6-0.40.30.4-0.7-0.6-0.5-0.40.7-0.70.4-0.5-0.4-0.71.11.0-1.01.00.3
Condit. Reinf. active responses0.60.81.9-0.9-0.80.51.4-1.4-1.0-0.70.60.7-0.7-0.8-0.7-0.80.9-0.80.7-0.9-0.7-0.81.00.9-0.91.30.4
Condit. Reinf. inactive responses0.30.41.1-0.6-0.50.41.0-1.0-0.8-0.70.60.7-0.4-0.6-0.5-0.60.5-0.50.5-0.6-0.5-0.50.60.6-0.50.90.3
Condit. Reinf. lever presses0.40.61.3-0.5-0.50.61.2-1.2-0.8-0.60.60.6-0.7-0.8-0.7-0.70.8-0.80.6-0.8-0.6-0.70.90.9-0.91.00.6
Condit. Reinf. lever reinforcers received0.40.61.9-0.8-0.70.41.4-1.4-0.8-0.60.40.6-0.6-0.7-0.5-0.70.7-0.70.6-0.8-0.5-0.60.90.8-0.81.20.4
Conditioned reinforcement - actives0.40.41.2-0.6-0.60.80.8-0.8-0.4-0.20.60.1-0.5-0.7-0.8-0.90.7-0.70.8-0.8-0.8-0.6-0.10.3-0.30.51.1
Conditioned reinforcement - inactives1.92.13.8-1.6-1.61.81.8-1.8-1.5-1.11.61.0-1.1-1.6-1.5-1.71.5-1.51.5-2.0-1.6-1.30.60.6-0.61.11.8
Conditioned locomotion0.20.21.9-0.0-0.00.20.1-0.10.20.60.3-0.7-0.1-0.2-0.4-0.60.3-0.30.6-0.4-0.6-0.4-0.7-0.30.3-0.31.4
Patch foraging indifference point 0 sec0.10.10.9-0.0-0.00.0-0.20.2-0.2-0.30.70.3-0.9-0.4-0.5-0.30.3-0.30.50.0-0.4-0.3-0.10.4-0.4-0.7-0.1
Patch foraging indifference point AUC1.41.73.1-1.2-1.11.31.5-1.5-1.2-0.81.20.8-1.3-1.4-1.4-1.51.3-1.31.4-1.8-1.4-1.30.81.2-1.31.11.6
Delay disc. indifference point, 0s delay1.01.11.81.01.2-1.1-0.80.80.90.4-1.2-0.31.11.21.31.3-1.21.2-1.41.41.41.3-0.6-0.60.6-0.3-1.2
Delay disc. indifference point, 16s delay1.81.83.5-1.5-1.61.31.6-1.6-1.7-1.91.51.9-1.8-1.4-1.3-1.11.1-1.11.2-0.6-1.1-1.11.41.2-1.10.50.4
Delay disc. indifference point, 2s delay0.10.10.4-0.0-0.00.0-0.00.0-0.0-0.4-0.30.50.30.40.50.5-0.50.5-0.50.60.50.5-0.0-0.20.30.0-0.6
Delay disc. indifference point, 24s delay5.55.47.8-2.4-2.42.32.3-2.3-2.4-2.02.32.0-2.8-2.5-2.5-2.42.4-2.42.5-2.0-2.4-2.52.42.4-2.41.61.5
Delay disc. indifference point, 4s delay0.30.31.7-0.6-0.60.50.5-0.5-0.5-1.20.41.3-0.3-0.10.10.2-0.20.3-0.20.50.30.30.1-0.30.4-0.1-0.6
Delay disc. indifference point, 8s delay2.12.13.2-1.6-1.61.31.3-1.3-1.5-1.11.31.1-1.3-1.5-1.4-1.51.5-1.51.5-1.2-1.5-1.61.81.7-1.81.61.0
Indifference point function ln k0.40.52.20.40.4-0.5-0.50.50.4-0.2-0.30.20.30.60.70.8-0.70.7-0.81.10.80.7-0.4-0.91.0-1.2-1.5
Indifference point function log k0.40.52.20.40.4-0.5-0.50.50.4-0.2-0.30.20.30.60.70.8-0.70.7-0.81.10.80.7-0.4-0.91.0-1.2-1.5
Patch foraging total patch changes 0 sec0.10.20.9-0.1-0.10.1-0.20.2-0.3-0.30.70.3-1.0-0.5-0.6-0.40.4-0.40.5-0.2-0.5-0.50.20.6-0.6-0.40.0
Patch foraging total patch changes 12 sec0.20.20.60.70.8-0.7-0.80.80.60.4-0.5-0.40.10.40.30.5-0.50.5-0.30.70.30.4-0.50.2-0.2-0.30.0
Patch foraging total patch changes 18 sec0.60.71.7-0.5-0.40.60.3-0.3-0.4-0.00.9-0.1-1.2-1.0-1.2-1.00.9-0.91.1-1.3-1.2-0.90.01.0-1.10.21.3
Patch foraging total patch changes 24 sec0.40.51.41.01.0-0.9-1.11.10.91.2-0.7-1.20.50.60.40.5-0.50.5-0.30.50.30.4-0.8-0.1-0.0-0.50.2
Patch foraging total patch changes 6 sec0.20.41.0-0.2-0.20.10.3-0.3-0.6-0.30.70.3-0.8-0.7-0.7-0.60.7-0.70.7-0.4-0.7-0.70.71.0-1.00.30.5
Patch foraging time to switch 0 sec0.20.41.0-0.5-0.60.50.3-0.3-0.40.00.3-0.1-0.5-0.6-0.7-0.60.7-0.70.7-0.6-0.7-0.70.60.9-1.00.80.7
Patch foraging water rate 0 sec0.20.41.00.30.4-0.3-0.10.10.2-0.2-0.40.30.60.60.80.7-0.80.8-0.71.00.70.7-0.3-0.70.8-0.5-1.0
Patch foraging water rate 12 sec3.35.06.92.52.5-2.3-2.22.22.11.3-2.4-1.22.22.42.52.6-2.42.5-2.62.62.52.4-1.6-2.12.1-1.7-1.9
Patch foraging water rate 18 sec0.81.11.91.41.4-1.3-1.01.01.11.1-1.3-1.01.41.21.21.1-1.01.0-1.01.21.00.8-0.3-0.70.6-0.1-0.5
Patch foraging water rate 24 sec2.23.16.02.42.5-2.3-1.91.91.92.1-2.2-2.02.11.91.81.7-1.61.6-1.71.61.61.5-1.1-0.90.8-0.4-0.7
Patch foraging water rate 6 sec1.72.53.81.71.9-1.8-1.81.81.51.1-1.7-1.01.51.71.71.8-1.71.7-1.81.91.71.7-1.2-1.11.1-1.1-1.4
Seeking ratio, delayed vs. immediate footshock0.30.31.20.60.6-0.7-0.70.70.81.0-0.2-1.00.40.30.10.0-0.20.2-0.0-0.6-0.00.2-1.1-0.60.5-0.40.7
Distance traveled before self-admin0.70.82.6-0.2-0.1-0.00.3-0.3-0.30.90.3-1.00.1-0.6-0.8-1.01.1-1.10.9-1.4-1.0-1.10.81.1-1.21.61.0
Distance traveled after self-admin0.10.10.60.30.3-0.40.1-0.10.00.5-0.2-0.50.60.10.1-0.10.1-0.1-0.1-0.20.0-0.10.20.2-0.20.80.0
Extensor digitorum longus weight4.517.823.1-4.0-4.03.74.4-4.4-4.3-2.84.42.7-4.3-4.6-4.6-4.74.7-4.74.7-4.8-4.6-4.74.04.1-4.13.43.6
Bone: elastic displacement0.10.10.4-0.7-0.70.30.5-0.5-0.2-0.4-0.20.40.10.00.20.1-0.10.1-0.10.10.10.10.40.1-0.10.4-0.2
Bone: elastic work0.40.52.0-1.4-1.40.90.8-0.8-0.7-0.80.40.8-0.5-0.5-0.4-0.40.5-0.50.4-0.3-0.4-0.51.00.6-0.60.8-0.2
Bone: endosteal estimation0.40.81.3-1.2-1.11.00.4-0.4-0.8-0.61.10.6-1.0-1.0-1.1-1.01.0-1.01.0-1.0-1.0-0.90.60.9-1.00.70.9
Bone: endosteal perimeter0.40.92.0-1.0-0.90.70.4-0.4-0.60.00.9-0.1-0.7-0.9-1.1-1.11.1-1.11.1-1.4-1.2-1.10.60.9-1.00.91.3
Epididymis fat weight9.421.831.35.45.3-5.3-5.65.65.55.2-5.2-5.15.05.04.54.5-4.54.5-4.34.44.14.1-4.3-4.13.8-3.6-1.8
Delta time in closed arm before/after self-admin0.10.11.20.00.1-0.3-0.40.40.20.1-0.2-0.10.20.30.30.3-0.20.2-0.30.40.30.20.20.0-0.0-0.1-1.1
Delta time in open arm before/after self-admin1.31.24.9-0.8-0.81.01.2-1.2-0.8-0.61.10.5-1.3-1.2-1.4-1.41.1-1.11.4-1.5-1.4-1.00.10.6-0.70.12.2
Diff in mean of infusions in LGA sessions0.20.30.7-0.6-0.60.60.8-0.8-0.3-0.60.60.6-0.7-0.4-0.4-0.40.2-0.20.4-0.5-0.4-0.2-0.3-0.30.4-0.80.1
Delay discount exponential model param2.12.23.41.81.8-1.6-1.71.71.71.7-1.5-1.71.41.51.31.4-1.41.4-1.40.91.31.4-1.7-1.41.4-1.4-0.6
Extinction: sum of active levers before priming1.51.52.7-0.9-0.91.01.1-1.1-1.3-0.60.90.6-1.0-1.2-1.2-1.31.4-1.41.2-1.4-1.2-1.41.61.6-1.61.60.7
Active lever presses in extinction session 60.20.21.5-0.1-0.10.10.2-0.20.50.4-0.1-0.40.30.10.1-0.1-0.10.10.1-0.2-0.10.1-0.8-1.21.1-0.90.6
Bone: final force0.20.31.7-0.8-0.80.40.4-0.4-0.4-1.20.51.3-0.6-0.20.00.1-0.20.2-0.20.20.30.3-0.1-0.40.5-0.7-1.0
Bone: final moment0.20.31.5-0.7-0.70.40.4-0.4-0.4-1.20.51.2-0.7-0.2-0.00.1-0.10.1-0.10.20.20.2-0.0-0.30.4-0.6-0.9
Food consumed during 24 hour testing period0.00.00.1-0.00.1-0.10.3-0.3-0.10.10.0-0.1-0.1-0.2-0.1-0.20.3-0.20.1-0.3-0.1-0.20.20.2-0.20.3-0.1
Glucose0.30.41.40.80.8-0.8-0.60.60.81.2-0.6-1.20.90.60.50.3-0.40.4-0.3-0.00.30.4-0.9-0.80.7-0.40.2
Heart weight7.09.913.53.53.6-3.7-3.63.63.63.3-3.3-3.23.23.33.13.2-3.13.1-3.12.83.13.1-3.2-2.72.6-2.1-1.8
Delay discount hyperbolic model param1.61.72.81.71.7-1.4-1.61.61.51.6-1.3-1.51.21.31.11.2-1.11.1-1.10.71.11.1-1.5-1.21.1-1.2-0.5
Intermittent access intake day 1-15 change1.31.32.30.90.9-1.0-0.50.50.90.2-1.1-0.11.01.21.41.5-1.41.4-1.51.21.51.5-1.0-1.31.4-1.3-1.4
Intermittent access intake escalation1.71.72.91.01.0-1.2-0.80.81.10.3-1.3-0.21.21.41.61.7-1.61.6-1.71.51.71.6-1.1-1.31.4-1.3-1.6
Intermittent access intake escalation 22.42.43.91.31.3-1.4-1.11.11.60.7-1.7-0.61.41.61.81.9-1.71.8-1.91.32.01.9-1.5-1.71.8-1.4-1.6
Intermitt. access day 1 inactive lever presses0.40.41.5-0.4-0.40.60.6-0.6-0.50.30.4-0.4-0.1-0.4-0.6-0.90.7-0.70.8-1.2-0.9-0.80.40.7-0.80.61.1
Intermitt. access day 15 inactive lever presses3.64.08.3-2.4-2.42.42.3-2.3-2.0-1.42.31.3-1.9-2.3-2.2-2.42.2-2.22.2-2.9-2.2-2.00.80.6-0.50.41.6
Intermitt. access escalation Index0.10.10.20.50.5-0.2-0.30.3-0.0-0.0-0.20.00.00.20.20.3-0.20.2-0.30.20.30.3-0.2-0.30.4-0.40.1
Intermittent access day 1 total infusions5.26.07.4-2.6-2.62.72.7-2.7-2.6-2.12.72.0-2.3-2.6-2.6-2.72.5-2.52.5-2.6-2.5-2.41.92.0-2.02.22.3
Intermittent access day 15 total infusions1.01.22.3-1.3-1.31.41.5-1.5-1.3-1.51.21.5-1.1-1.1-0.9-0.90.9-0.90.8-0.9-0.7-0.70.80.8-0.71.00.5
Intermittent access terminal intake (last 3 days)1.01.12.6-1.5-1.51.51.6-1.6-1.2-1.41.11.4-0.9-1.0-0.8-0.90.8-0.80.7-1.1-0.7-0.60.50.4-0.30.90.5
Intermittent access total infusions1.61.73.0-1.6-1.61.61.7-1.7-1.5-1.31.41.3-1.1-1.3-1.2-1.41.2-1.21.2-1.2-1.2-1.10.90.8-0.81.41.3
Intermittent access day 1 locomotion2.52.65.1-1.7-1.71.81.8-1.8-1.7-1.01.90.9-1.2-1.7-1.8-1.91.7-1.71.8-1.9-1.8-1.60.91.2-1.21.32.3
Intermittent access day 15 total locomotion0.50.52.1-0.8-0.80.70.9-0.9-0.6-0.40.90.3-0.4-0.7-0.7-0.80.6-0.60.8-0.7-0.8-0.60.10.6-0.60.81.5
Intermittent access total locomotion0.30.41.6-0.8-0.80.70.9-0.9-0.6-0.40.70.4-0.2-0.5-0.5-0.70.4-0.50.6-0.6-0.6-0.40.10.2-0.20.71.2
Intermittent access standard deviation0.10.10.20.20.2-0.1-0.00.00.30.3-0.2-0.30.50.30.30.2-0.20.2-0.20.10.20.2-0.3-0.40.40.10.1
Left kidney weight0.00.10.6-0.1-0.00.10.1-0.10.40.10.1-0.10.1-0.0-0.0-0.1-0.10.10.1-0.3-0.10.1-0.7-0.60.6-0.30.5
Right kidney weight0.41.12.91.51.4-1.3-1.31.31.51.7-1.1-1.71.10.90.70.7-0.70.7-0.70.50.60.6-1.1-0.70.5-0.20.2
Cocaine induced anxiety0.20.20.7-0.3-0.30.50.1-0.1-0.3-0.00.6-0.0-0.5-0.5-0.6-0.60.6-0.60.6-0.8-0.6-0.50.10.3-0.3-0.10.4
Post-drug Anxiety0.10.20.80.10.20.1-0.70.70.4-0.10.00.1-0.20.20.10.3-0.40.4-0.30.20.30.5-0.8-0.50.5-0.9-0.3
Baseline Anxiety0.20.20.60.30.3-0.3-0.50.50.40.0-0.5-0.00.60.50.60.6-0.60.6-0.60.70.60.7-0.4-0.40.40.1-0.4
Tail length0.10.21.00.40.3-0.3-0.70.70.30.50.1-0.6-0.3-0.2-0.5-0.30.4-0.40.4-0.5-0.4-0.3-0.10.5-0.50.31.0
Length with tail0.41.34.91.61.7-1.5-1.91.91.52.2-1.2-2.21.00.90.40.6-0.40.4-0.40.30.30.3-0.70.1-0.30.20.6
Length without tail0.20.52.01.11.2-1.1-1.01.00.91.4-0.7-1.40.70.60.30.3-0.30.3-0.20.20.20.1-0.30.1-0.20.10.1
Times rat made contact with spout4.55.27.4-2.3-2.22.52.2-2.2-2.5-2.22.72.1-2.6-2.6-2.5-2.42.4-2.42.5-2.2-2.3-2.42.02.2-2.11.51.2
Lifetime Intake1.82.13.4-1.7-1.81.81.8-1.8-1.6-1.41.61.4-1.2-1.5-1.4-1.51.4-1.41.4-1.4-1.3-1.30.90.7-0.71.41.3
Liver weight, left1.22.03.41.91.8-1.4-1.81.81.71.5-1.6-1.51.41.51.31.4-1.31.3-1.31.21.31.2-1.3-1.21.0-0.7-0.2
Liver weight, right5.99.813.93.43.4-3.2-3.73.73.53.2-3.5-3.13.53.43.23.2-3.13.1-3.23.23.13.0-2.7-2.82.6-1.7-1.8
Locomotor activity0.20.31.8-0.6-0.60.50.7-0.7-0.6-1.30.51.3-0.7-0.4-0.10.0-0.10.10.00.20.00.10.20.2-0.1-0.0-0.6
Locomotor testing distance0.81.43.2-1.5-1.51.41.6-1.6-1.4-1.81.31.8-1.3-1.2-1.0-0.90.8-0.70.9-0.6-0.9-0.70.91.0-0.90.70.2
Locomotor testing rearing0.71.11.9-1.2-1.21.21.4-1.4-0.9-0.70.80.6-1.0-1.0-1.0-1.11.0-1.01.1-0.9-1.1-1.00.81.1-1.11.11.0
Locomotion in novel chamber1.31.62.71.31.3-1.3-1.51.51.41.4-1.2-1.41.01.31.11.1-1.21.2-1.00.71.01.1-1.6-1.41.3-1.6-0.7
Locomotion in novel chamber post-restriction1.51.83.31.01.0-1.1-1.11.11.20.8-1.6-0.71.81.61.71.5-1.51.5-1.61.61.61.5-1.0-1.41.4-0.2-1.2
Fecal boli incidents, locomotor time 10.50.61.6-0.7-1.01.00.9-0.9-1.2-1.20.71.2-0.4-0.5-0.2-0.20.4-0.30.1-0.2-0.0-0.31.20.4-0.20.2-1.3
Change in fecal boli incidents, locomotor task3.12.95.71.92.1-2.2-1.91.92.12.4-2.2-2.42.21.91.71.6-1.41.4-1.61.11.51.4-1.2-1.00.8-0.0-0.0
Time >=10cm from walls, locomotor time 11.21.24.50.30.6-0.60.5-0.50.2-0.6-1.10.71.31.11.61.4-1.21.3-1.61.51.61.20.6-0.70.80.2-2.1
Bouts of movement, locomotor time 13.74.05.9-1.9-2.12.21.9-1.9-2.4-1.82.01.7-2.1-2.1-2.1-2.02.2-2.22.0-1.7-2.0-2.22.42.0-2.01.91.2
Total resting periods, locomotor time 13.23.55.9-1.8-2.02.21.8-1.8-2.3-1.92.01.9-2.0-1.9-1.8-1.72.0-1.91.7-1.4-1.6-1.92.41.8-1.71.70.7
Rest time, locomotor task time 10.20.20.8-0.5-0.50.70.2-0.2-0.5-0.70.40.7-0.3-0.2-0.1-0.00.2-0.20.10.2-0.1-0.30.90.4-0.40.4-0.5
Distance moved, locomotor task time 10.60.71.50.80.7-0.9-0.80.81.00.6-0.7-0.60.60.70.70.7-0.90.9-0.70.80.70.9-1.2-1.00.9-1.1-0.2
Vertical activity count, locomotor time 10.60.61.11.01.0-1.0-0.80.80.80.7-0.8-0.71.00.90.80.8-0.90.9-0.80.80.70.8-0.8-0.70.6-0.6-0.3
Time >=10cm from walls, locomotor time 21.21.22.40.50.7-0.90.3-0.30.90.4-1.2-0.41.51.31.51.1-1.41.4-1.30.91.31.3-0.8-1.51.5-0.9-1.4
Bouts of movement, locomotor time 20.30.30.80.60.4-0.6-0.40.40.40.4-0.8-0.40.60.60.70.7-0.40.4-0.70.50.70.40.50.4-0.40.9-0.8
Total resting periods, locomotor time 20.20.21.20.30.1-0.3-0.10.10.20.3-0.5-0.30.40.30.40.3-0.10.1-0.40.20.40.10.60.6-0.71.1-0.4
Rest time, locomotor task time 21.31.53.3-1.7-1.51.81.7-1.7-1.4-1.01.10.9-0.9-1.2-1.1-1.31.2-1.21.2-1.1-1.2-1.21.10.7-0.70.90.7
Distance moved, locomotor task time 20.81.02.51.21.2-1.6-1.21.21.31.0-0.8-1.00.70.80.70.7-0.90.9-0.70.70.70.9-1.4-0.90.8-1.2-0.1
Vertical activity count, locomotor time 21.81.93.01.51.6-1.7-1.61.61.71.2-1.2-1.21.21.51.41.3-1.51.5-1.31.41.21.4-1.4-1.21.1-1.4-1.0
Light reinforcement 14.27.710.3-2.6-2.52.82.6-2.6-2.7-2.02.91.9-3.2-3.1-3.2-3.13.0-3.03.1-3.0-3.1-2.92.02.7-2.82.33.0
Light reinforcement 22.83.86.0-2.2-2.22.12.0-2.0-2.2-2.42.42.3-2.2-2.2-2.0-1.81.8-1.81.8-1.6-1.7-1.61.51.6-1.51.51.3
Bone: marrow area0.51.01.4-1.2-1.11.10.5-0.5-0.9-0.61.20.6-1.1-1.1-1.2-1.11.1-1.11.1-1.1-1.1-1.10.71.1-1.10.91.0
Bone: maximum diameter0.91.73.1-1.5-1.51.21.3-1.3-1.3-0.91.50.8-1.4-1.5-1.5-1.51.4-1.41.5-1.8-1.5-1.41.01.0-1.00.81.1
Bone: maximum force0.00.00.1-0.3-0.2-0.1-0.00.00.0-0.10.10.1-0.2-0.1-0.0-0.00.0-0.00.0-0.10.0-0.0-0.1-0.10.2-0.2-0.3
Bone: maximum moment0.00.00.1-0.3-0.2-0.0-0.00.0-0.0-0.10.10.1-0.3-0.1-0.1-0.10.1-0.10.1-0.2-0.1-0.10.0-0.00.0-0.1-0.2
Mean time between licks in bursts2.23.14.91.81.8-2.0-2.22.21.82.1-2.1-2.12.12.01.81.7-1.61.6-1.61.71.61.4-1.3-1.41.3-1.1-0.9
Mean num. licks in bursts0.20.20.8-0.5-0.50.80.4-0.4-0.4-0.90.70.9-0.7-0.4-0.4-0.20.0-0.10.3-0.1-0.2-0.0-0.3-0.30.4-0.9-0.2
Cd content in liver0.10.10.6-0.4-0.40.30.4-0.40.10.2-0.4-0.20.40.30.40.2-0.10.2-0.3-0.20.30.20.2-0.10.10.1-0.7
Co content in liver5.86.810.2-2.9-3.02.92.8-2.8-2.9-2.42.52.3-2.4-2.6-2.3-2.42.6-2.62.3-2.4-2.2-2.53.23.0-2.82.81.2
Cu content in liver1.01.22.6-1.5-1.61.51.2-1.2-1.3-1.21.11.2-1.0-1.1-0.9-0.91.0-0.90.8-0.9-0.8-0.81.01.0-0.91.00.0
Fe content in liver0.40.41.5-0.3-0.30.40.6-0.60.1-0.4-0.20.40.20.30.60.4-0.60.6-0.60.30.70.8-0.9-1.21.2-1.2-1.0
K content in liver0.30.30.70.20.2-0.2-0.50.5-0.30.40.6-0.5-0.5-0.5-0.8-0.60.7-0.70.8-0.3-0.8-0.80.20.6-0.60.10.9
Mg content in liver0.70.82.1-0.4-0.50.40.0-0.0-0.7-0.51.30.4-1.4-1.1-1.4-1.11.0-1.01.3-0.7-1.2-1.00.00.6-0.6-0.31.2
Mn content in liver0.60.71.8-0.2-0.20.10.1-0.1-0.20.70.5-0.8-0.6-0.7-1.0-1.00.9-1.01.2-0.9-1.3-1.20.61.0-1.10.41.3
Na content in liver0.80.91.8-1.3-1.21.20.5-0.5-0.8-0.51.20.4-1.0-1.0-1.2-1.11.0-1.01.1-1.1-1.1-0.90.10.4-0.40.11.1
Rb content in liver0.40.51.6-0.4-0.40.30.2-0.2-0.7-0.91.00.8-1.3-0.9-1.0-0.60.7-0.70.8-0.1-0.8-0.70.40.8-0.70.00.6
Se content in liver0.20.20.90.50.5-0.3-0.40.40.40.9-0.0-1.0-0.1-0.1-0.4-0.30.3-0.30.4-0.3-0.5-0.3-0.5-0.1-0.0-0.40.8
Sr content in liver0.20.20.80.20.2-0.2-0.60.60.60.9-0.6-0.90.70.40.30.3-0.10.1-0.4-0.20.30.3-0.3-0.20.10.70.3
Zn content in liver0.20.21.1-0.2-0.30.30.0-0.0-0.00.40.2-0.4-0.3-0.4-0.6-0.60.5-0.50.6-0.5-0.6-0.5-0.20.2-0.20.31.0
Bone: minimum diameter0.10.30.7-0.4-0.30.1-0.20.2-0.3-0.00.7-0.0-0.6-0.6-0.7-0.60.6-0.60.6-0.8-0.6-0.60.20.6-0.60.40.6
Time in familiar zone, hab. session 10.10.10.70.50.5-0.5-0.60.60.50.3-0.1-0.3-0.10.10.10.2-0.20.2-0.2-0.00.20.3-0.7-0.30.3-0.8-0.2
Time in novel zone, hab. session 11.00.91.81.01.0-1.1-0.90.91.01.1-1.2-1.11.31.21.10.9-1.01.0-0.91.00.90.8-0.6-0.70.7-0.3-0.5
Total zone transitions, hab. session 10.00.10.4-0.5-0.50.40.2-0.2-0.1-0.1-0.10.10.00.10.20.1-0.10.1-0.20.30.20.10.2-0.10.20.0-0.6
Total locomotion distance, hab. session 10.00.10.2-0.2-0.30.1-0.10.10.20.4-0.2-0.40.20.20.20.1-0.10.1-0.10.10.10.1-0.3-0.40.5-0.3-0.2
Locomotion velocity, hab. session 10.20.30.9-0.9-1.00.80.7-0.7-0.5-0.10.50.1-0.4-0.5-0.5-0.70.7-0.70.6-0.6-0.6-0.60.40.3-0.30.60.5
Time in familiar zone, hab. session 20.20.30.8-0.4-0.40.80.1-0.1-0.4-0.70.90.7-0.9-0.6-0.6-0.40.3-0.30.5-0.5-0.4-0.2-0.3-0.10.1-0.70.3
Time in novel zone, hab. session 20.70.71.61.01.0-1.2-0.60.60.91.2-1.3-1.21.20.90.90.7-0.70.7-0.80.70.70.6-0.2-0.30.20.2-0.4
Total zone transitions, hab. session 20.20.20.8-0.5-0.50.60.2-0.2-0.6-0.70.70.7-0.9-0.5-0.4-0.30.4-0.40.3-0.1-0.3-0.40.50.3-0.2-0.1-0.3
Total locomotion distance, hab. session 20.20.30.6-0.3-0.30.40.1-0.1-0.30.10.5-0.1-0.7-0.6-0.7-0.60.8-0.80.7-0.7-0.7-0.80.40.4-0.40.20.6
Locomotion velocity, hab. session 20.40.51.0-0.5-0.50.70.4-0.4-0.7-0.30.80.2-1.0-0.9-0.9-0.81.0-1.00.9-0.8-0.9-1.00.70.6-0.60.40.7
Novel to familiar place preference ratio2.02.13.61.41.4-1.7-1.21.21.61.7-1.9-1.61.91.71.71.4-1.41.4-1.41.31.41.3-1.0-1.21.1-0.9-1.4
Novelty place preference2.62.74.31.71.7-1.8-1.41.41.81.7-2.1-1.72.01.91.91.6-1.71.7-1.61.61.61.5-1.2-1.41.3-1.1-1.5
Time in novel zone, NPP test2.62.74.21.71.7-1.9-1.51.51.81.7-2.1-1.72.01.91.91.6-1.71.7-1.61.61.61.5-1.2-1.41.3-1.1-1.6
Total zone transitions, NPP test1.62.23.0-1.7-1.71.71.3-1.3-1.7-1.31.71.3-1.7-1.6-1.5-1.41.6-1.51.4-1.1-1.4-1.51.71.7-1.61.40.9
Total locomotion distance, NPP test1.01.42.0-1.4-1.41.21.1-1.1-1.1-0.51.10.4-1.1-1.2-1.2-1.21.4-1.41.2-1.2-1.2-1.41.31.3-1.21.20.9
Locomotion velocity, NPP test2.23.14.3-2.1-2.12.01.7-1.7-1.8-1.11.81.1-1.8-1.9-1.9-1.92.0-2.01.9-1.8-1.8-1.91.71.6-1.61.51.4
Intraocular pressure2.12.95.21.31.3-1.6-1.51.51.40.4-1.8-0.31.61.82.12.2-2.02.0-2.22.32.32.1-0.9-1.31.4-0.8-2.3
Delta distance traveled before/after self-admin1.41.52.81.11.1-1.0-0.90.91.20.6-1.0-0.61.01.21.21.2-1.31.3-1.31.21.31.4-1.5-1.71.7-1.6-0.8
Delta ambulatory time before/after self-admin0.50.51.50.40.4-0.3-0.30.30.6-0.0-0.60.10.60.70.80.8-0.90.9-0.80.80.80.9-0.9-1.21.2-1.1-0.4
Parametrial fat weight3.77.213.13.63.6-3.4-3.23.22.92.5-2.9-2.42.52.82.52.8-2.62.6-2.62.92.52.5-2.2-1.81.7-1.9-1.1
Pavlov. Cond. lever latency2.73.56.52.22.2-2.4-1.81.82.32.6-2.4-2.62.22.01.81.6-1.71.7-1.61.41.51.5-1.7-1.41.3-1.0-0.6
Pavlov. Cond. magazine entry latency0.50.60.9-0.6-0.60.90.3-0.3-0.8-0.51.00.5-0.7-0.9-0.9-0.80.9-0.90.8-0.9-0.8-0.80.70.8-0.80.90.9
Pavlov. Cond. change in total contacts0.70.71.6-1.0-1.01.30.5-0.5-1.0-1.01.11.0-0.7-0.9-0.8-0.70.8-0.80.6-0.7-0.6-0.60.80.7-0.70.90.5
Pavlov. Cond. index score1.41.73.2-1.5-1.51.81.1-1.1-1.6-1.61.71.6-1.4-1.4-1.3-1.21.3-1.31.2-1.1-1.1-1.11.21.1-1.01.00.7
Pavlov. Cond. latency score1.31.62.9-1.4-1.41.71.1-1.1-1.6-1.61.61.6-1.3-1.4-1.3-1.21.2-1.21.1-1.1-1.0-1.11.21.1-1.00.90.6
Pavlov. Cond. lever contacts2.02.44.1-1.8-1.82.01.3-1.3-1.9-1.91.91.8-1.6-1.7-1.5-1.41.5-1.51.4-1.2-1.3-1.41.51.4-1.21.10.8
Pavlov. Cond. magazine entry number0.50.61.30.80.8-1.1-0.50.50.90.8-1.1-0.70.70.90.90.8-0.90.9-0.70.90.70.7-0.6-0.60.6-0.7-0.6
Pavlov. Cond. intertrial magazine entries0.70.93.8-1.3-1.31.01.5-1.5-1.1-1.90.72.0-0.8-0.6-0.1-0.20.1-0.10.10.1-0.0-0.00.70.10.10.1-1.1
Pavlov. Cond. lever-magazine prob. diff.2.32.94.9-2.0-1.92.21.5-1.5-2.0-1.92.11.9-1.7-1.8-1.7-1.61.7-1.71.5-1.5-1.5-1.51.61.5-1.41.41.0
Pavlov. Cond. response bias1.61.94.0-1.6-1.62.01.2-1.2-1.7-1.81.91.8-1.6-1.6-1.4-1.31.3-1.31.2-1.2-1.2-1.11.11.0-0.90.90.7
Pavlov. Cond. lever latency1.01.31.81.21.2-1.2-1.31.31.31.1-1.1-1.11.21.21.11.0-1.11.1-1.00.91.01.1-1.3-1.31.2-1.2-0.5
Pavlov. Cond. magazine entry latency0.10.10.5-0.3-0.30.50.4-0.4-0.3-0.10.20.0-0.2-0.3-0.3-0.40.3-0.30.4-0.1-0.5-0.40.30.3-0.40.20.7
Pavlov. Cond. change in total contacts0.30.41.7-0.3-0.30.40.8-0.8-0.8-0.50.20.5-0.4-0.5-0.3-0.40.6-0.60.4-0.2-0.4-0.61.31.0-1.01.1-0.0
Pavlov. Cond. index score0.30.30.6-0.5-0.50.60.8-0.8-0.6-0.30.30.3-0.4-0.5-0.5-0.60.6-0.60.6-0.4-0.6-0.60.70.7-0.70.70.5
Pavlov. Cond. latency score0.20.30.6-0.5-0.50.60.8-0.8-0.6-0.30.30.3-0.4-0.5-0.5-0.60.6-0.60.6-0.4-0.6-0.60.60.6-0.60.60.5
Pavlov. Cond. lever contacts0.50.71.9-0.7-0.60.70.8-0.8-0.9-0.50.50.5-0.6-0.7-0.7-0.70.8-0.80.7-0.5-0.7-0.81.31.3-1.31.40.5
Pavlov. Cond. magazine entry number0.10.10.50.20.2-0.4-0.20.20.2-0.3-0.00.30.00.20.30.4-0.40.4-0.50.00.50.5-0.5-0.50.6-0.5-0.7
Pavlov. Cond. intertrial magazine entries2.93.75.51.71.7-2.2-2.02.02.21.8-1.9-1.82.12.01.91.9-2.01.9-1.91.41.92.0-2.3-2.22.1-1.7-1.4
Pavlov. Cond. lever-magazine prob. diff.0.10.10.3-0.2-0.20.40.5-0.5-0.3-0.20.10.2-0.1-0.2-0.2-0.30.2-0.20.2-0.1-0.3-0.30.50.4-0.40.40.2
Pavlov. Cond. response bias0.91.22.4-1.0-1.01.11.1-1.1-1.2-0.80.80.8-0.9-1.0-1.0-1.01.1-1.11.0-0.7-1.1-1.21.61.5-1.51.50.9
Time in closed arm before self-admin0.80.91.41.11.1-1.1-0.60.61.11.1-1.1-1.11.21.01.00.9-0.80.8-1.00.60.90.9-1.0-1.11.1-0.60.3
Time in closed arm after self-admin0.91.02.31.11.1-1.3-1.01.01.11.5-1.2-1.51.41.01.00.8-0.70.7-0.90.40.90.7-0.6-0.90.8-0.1-0.4
Time in open arm before self-admin0.30.31.1-0.6-0.60.50.1-0.1-0.6-0.80.40.8-0.4-0.3-0.2-0.10.2-0.20.10.2-0.1-0.31.00.7-0.70.5-1.0
Time in open arm after self-admin3.03.34.8-1.9-2.02.11.8-1.8-2.0-1.92.11.8-2.2-2.0-2.0-1.91.8-1.81.9-1.8-1.9-1.71.31.7-1.71.01.4
Bone: periosteal estimation0.61.11.7-1.3-1.30.90.8-0.8-1.0-0.71.20.6-1.1-1.2-1.2-1.21.2-1.21.2-1.3-1.2-1.10.91.1-1.10.90.8
Bone: periosteal perimeter0.40.61.5-0.6-0.50.20.3-0.3-0.60.10.6-0.1-0.6-0.7-0.8-0.81.0-1.00.8-1.2-0.9-1.00.81.0-1.01.00.8
Bone: post-yield work0.71.01.7-0.8-0.70.80.8-0.8-0.8-0.11.00.1-0.8-1.0-1.2-1.31.2-1.21.2-1.3-1.3-1.20.80.9-0.90.81.2
Progressive ratio test 1 active lever presses0.50.51.4-0.9-0.91.01.0-1.0-0.8-0.20.70.20.3-0.5-0.5-0.90.7-0.70.6-0.9-0.7-0.60.30.0-0.01.11.2
Progressive ratio test 1 breakpoint0.50.51.4-0.9-0.91.01.0-1.0-0.7-0.20.60.10.3-0.5-0.5-0.80.6-0.60.6-0.9-0.7-0.60.3-0.00.01.11.2
Progressive ratio test 1 inactive lever presses1.31.42.9-1.4-1.41.31.4-1.4-1.2-0.31.00.3-0.6-1.1-1.1-1.51.4-1.41.3-1.7-1.3-1.30.80.6-0.61.21.5
Progressive ratio test 2 active lever presses0.10.10.4-0.4-0.40.40.5-0.5-0.1-0.30.20.3-0.1-0.2-0.2-0.20.1-0.10.1-0.3-0.10.0-0.3-0.00.00.70.6
Progressive ratio test 2 breakpoint0.10.10.3-0.4-0.40.50.6-0.6-0.2-0.40.20.4-0.0-0.2-0.1-0.20.0-0.00.1-0.3-0.10.1-0.3-0.10.10.60.5
Progressive ratio test 2 inactive lever presses0.60.71.8-1.2-1.21.21.3-1.3-0.8-1.00.81.0-0.6-0.8-0.7-0.80.6-0.60.6-0.9-0.6-0.40.10.1-0.10.60.7
Incentive Sensitization - Responses0.20.20.70.40.3-0.4-0.10.10.50.1-0.5-0.10.30.40.40.5-0.60.6-0.60.20.60.7-0.9-0.40.40.10.0
Incentive Sensitization - Breakpoint0.20.20.80.50.4-0.5-0.20.20.60.2-0.6-0.20.40.50.50.6-0.60.6-0.60.20.60.7-0.9-0.40.30.10.1
Sum of active levers in priming session hrs 5-61.21.22.1-1.2-1.31.31.0-1.0-1.0-1.01.30.9-1.4-1.3-1.3-1.21.2-1.21.2-1.4-1.2-1.10.60.5-0.5-0.00.1
Progressive ratio0.80.92.01.01.0-1.0-0.80.81.21.4-0.8-1.41.00.90.60.5-0.80.7-0.40.30.30.6-1.4-1.21.1-1.10.6
Food seeking constrained by brief footshock1.31.63.7-1.9-1.81.61.9-1.9-1.4-1.91.31.9-1.4-1.3-1.0-1.10.9-0.91.0-0.9-0.9-0.80.80.5-0.40.50.3
Seeking ratio, punishment vs. effort1.11.44.5-1.5-1.41.41.5-1.5-1.5-2.11.02.1-1.1-1.0-0.5-0.40.7-0.60.4-0.1-0.2-0.51.61.2-0.91.2-0.9
Retroperitoneal fat weight13.343.770.98.28.2-8.0-8.18.17.88.4-7.4-8.47.26.95.95.9-5.85.8-5.65.35.35.4-6.2-5.24.7-4.3-2.0
Reaction time number correct0.10.20.8-0.3-0.30.30.9-0.9-0.3-0.80.10.8-0.6-0.3-0.1-0.10.1-0.10.0-0.0-0.00.00.20.1-0.0-0.0-0.4
Reaction time mean minus median0.10.20.6-0.4-0.50.50.4-0.40.1-0.50.10.5-0.2-0.00.00.0-0.30.3-0.00.00.10.4-0.8-0.60.6-0.8-0.1
Reaction time mean minus median AUC0.30.41.30.00.00.10.1-0.10.4-0.5-0.30.50.10.40.60.7-0.80.8-0.70.50.70.9-1.0-1.01.1-1.1-1.0
Reaction time num false alarms1.01.44.5-0.6-0.60.70.7-0.7-1.4-1.21.01.2-1.3-1.1-1.0-0.71.1-1.10.8-0.6-0.7-1.12.12.1-2.01.6-0.3
Reaction time num false alarms AUC1.42.05.7-0.8-0.91.01.0-1.0-1.6-1.21.21.2-1.4-1.3-1.2-1.01.5-1.41.1-1.0-1.0-1.42.42.4-2.32.10.1
Reaction time trials correct on left0.10.20.8-0.3-0.30.30.9-0.9-0.3-0.80.10.8-0.6-0.3-0.1-0.10.1-0.10.0-0.0-0.00.00.20.1-0.0-0.0-0.4
Reaction time trials on left0.10.20.8-0.3-0.30.30.9-0.9-0.3-0.90.20.9-0.7-0.3-0.1-0.10.1-0.10.1-0.1-0.0-0.00.30.1-0.00.0-0.4
Reaction time mean0.30.41.40.10.00.20.0-0.00.3-0.4-0.20.50.30.50.60.6-0.80.8-0.70.50.80.9-0.9-1.11.2-1.0-1.1
Reaction time mean AUC0.20.30.9-0.0-0.10.30.1-0.10.2-0.4-0.20.50.20.30.50.5-0.60.6-0.60.30.60.8-0.8-0.91.0-0.7-0.9
Median of all reaction times0.30.51.90.0-0.00.20.1-0.10.1-0.6-0.10.60.30.40.70.7-0.70.7-0.80.40.90.9-0.7-1.11.2-0.9-1.4
Reaction time omissions0.10.21.0-0.5-0.50.60.4-0.4-0.5-1.00.41.0-0.4-0.10.00.1-0.20.2-0.10.30.20.20.10.00.1-0.1-0.7
Reaction time false alarm rate0.91.34.0-0.5-0.60.70.3-0.3-1.2-0.41.00.4-0.8-1.0-1.1-0.91.3-1.31.0-0.9-1.0-1.31.92.0-2.01.80.5
Reaction time premature initiation rate0.20.31.60.40.4-0.2-0.50.50.00.7-0.1-0.80.4-0.0-0.2-0.30.4-0.40.3-0.2-0.4-0.50.60.7-0.81.21.1
Reaction time premature initiations0.10.11.00.30.2-0.1-0.10.1-0.10.3-0.1-0.30.1-0.1-0.2-0.20.3-0.30.2-0.1-0.3-0.40.60.6-0.71.00.6
Std. dev. reaction times0.30.51.40.20.10.1-0.20.20.5-0.2-0.40.20.30.50.60.7-0.90.9-0.70.60.70.9-1.1-1.11.2-1.1-0.8
Reaction time trials completed0.10.20.8-0.3-0.30.30.9-0.9-0.3-0.90.20.9-0.7-0.3-0.1-0.10.1-0.10.1-0.1-0.0-0.00.30.1-0.00.0-0.4
Reaction time trials AUC0.20.31.2-0.5-0.50.51.1-1.1-0.4-1.00.31.1-0.8-0.4-0.2-0.20.1-0.10.1-0.1-0.1-0.00.20.00.1-0.1-0.4
Run reversals in cocaine runway, females0.10.10.50.40.4-0.2-0.10.10.20.7-0.3-0.70.10.20.1-0.00.0-0.00.00.2-0.1-0.1-0.1-0.0-0.10.00.3
Run reversals in cocaine runway, males0.40.41.2-0.5-0.60.60.5-0.5-0.6-0.20.40.2-0.1-0.5-0.5-0.60.6-0.60.6-0.6-0.6-0.60.70.9-0.91.10.7
Latency to leave start box in cocaine runway0.40.41.0-0.7-0.70.60.8-0.8-0.5-0.60.60.5-1.0-0.8-0.8-0.70.6-0.60.8-0.7-0.8-0.60.20.5-0.5-0.00.4
Latency to leave start box in cocaine runway, F1.21.42.2-1.1-1.10.91.0-1.0-1.0-0.81.10.7-1.3-1.3-1.3-1.21.2-1.21.3-1.1-1.3-1.31.11.4-1.51.01.2
Latency to leave start box in cocaine runway, M0.10.10.60.20.2-0.20.2-0.20.3-0.0-0.30.0-0.00.20.30.3-0.40.4-0.30.20.30.4-0.5-0.60.7-0.8-0.7
Std. dev. time between licks in bursts0.00.00.2-0.1-0.1-0.20.1-0.10.00.3-0.4-0.30.40.20.20.1-0.00.0-0.10.10.1-0.00.40.1-0.10.4-0.2
Total sessions with >9 infusions0.30.30.9-0.8-0.80.80.9-0.9-0.9-0.50.40.50.3-0.3-0.0-0.40.4-0.30.2-0.4-0.2-0.30.5-0.30.40.6-0.2
Short access day 1 total inactive lever presses3.23.66.0-2.4-2.42.42.4-2.4-2.0-1.41.91.4-1.3-1.9-1.8-2.11.9-1.91.9-2.3-1.9-1.71.31.0-1.01.62.0
Short access day 10 total inactive lever presses0.40.41.2-0.4-0.50.60.6-0.6-0.2-0.10.70.0-0.8-0.7-0.8-0.90.6-0.60.8-1.1-0.8-0.6-0.4-0.30.2-1.10.6
Short access day 1 total infusions1.61.73.8-1.7-1.71.91.8-1.8-1.6-1.31.41.2-0.9-1.3-1.0-1.41.3-1.21.1-1.3-1.1-1.21.10.4-0.31.20.6
Short access day 10 total infusions2.83.15.2-2.2-2.22.32.2-2.2-2.1-1.72.01.6-1.4-1.8-1.6-1.91.8-1.81.7-1.9-1.6-1.61.30.9-0.81.61.1
Short access total infusions1.11.32.8-1.4-1.41.71.5-1.5-1.4-1.21.41.2-0.8-1.2-1.0-1.21.1-1.11.0-1.2-1.0-0.90.60.1-0.00.70.8
Short access day 1 locomotion3.13.35.7-2.1-2.22.42.2-2.2-1.9-1.22.11.1-1.4-1.9-1.8-2.22.1-2.01.9-2.2-1.9-1.91.40.9-0.91.31.3
Short access day 10 total locomotion0.70.82.0-1.2-1.31.41.1-1.1-1.1-0.61.10.60.1-0.7-0.7-1.00.7-0.70.9-0.9-0.9-0.70.40.2-0.20.71.2
Short access total locomotion0.30.30.9-0.7-0.81.00.8-0.8-0.6-0.40.60.40.5-0.2-0.1-0.50.2-0.20.3-0.4-0.3-0.1-0.1-0.60.70.20.6
One hour access (0.3 mA shock)1.01.23.6-1.4-1.51.61.6-1.6-1.3-1.91.21.9-1.2-1.1-0.8-0.70.7-0.70.6-0.8-0.5-0.40.40.10.10.4-0.1
Compulsive drug intake0.60.61.20.70.7-0.7-0.70.70.7-0.1-0.60.2-0.00.60.61.0-0.90.9-0.90.80.91.0-0.8-0.60.6-1.1-1.1
One hour access (shock baseline)1.41.62.8-1.7-1.71.71.7-1.7-1.5-1.21.31.2-0.6-1.2-1.0-1.31.3-1.31.1-1.2-1.1-1.11.10.6-0.51.60.9
Social response proportion0.20.20.50.60.6-0.7-0.40.40.40.6-0.5-0.60.20.40.10.2-0.30.3-0.00.5-0.10.1-0.4-0.0-0.1-0.20.6
Social responses0.70.93.60.20.2-0.30.2-0.20.01.30.3-1.5-0.2-0.6-1.0-1.31.0-1.11.3-1.5-1.4-1.2-0.10.6-0.80.51.9
Social time0.40.51.81.01.0-0.7-0.60.60.90.7-0.6-0.70.40.60.40.5-0.70.7-0.40.40.30.6-1.3-1.01.0-1.10.1
Soleus weight5.516.120.1-3.8-3.73.64.1-4.1-4.3-2.94.12.8-3.8-4.3-4.2-4.34.5-4.44.2-4.5-4.1-4.34.34.3-4.23.93.1
Bone: stiffness0.00.00.10.20.3-0.4-0.20.20.10.1-0.0-0.1-0.1-0.00.00.00.0-0.0-0.1-0.10.10.0-0.00.0-0.00.1-0.2
Tibialis anterior weight3.712.515.2-3.5-3.43.23.6-3.6-3.8-2.83.82.6-3.7-3.9-3.9-3.93.9-3.93.9-3.6-3.8-3.93.43.5-3.52.72.9
Time to tail flick, vehicle, before self-admin1.61.63.11.31.3-1.2-1.21.21.11.0-1.4-1.01.81.51.51.4-1.31.3-1.41.61.41.2-0.5-1.01.1-0.3-1.5
Time to tail flick, vehicle, after self-admin1.21.33.21.41.4-1.3-1.61.61.71.8-1.1-1.80.91.00.70.7-0.70.7-0.60.70.60.6-1.1-1.00.9-1.00.2
Time to tail flick, test, before self-admin0.50.51.1-0.8-0.80.90.9-0.9-0.8-0.70.60.7-0.5-0.8-0.6-0.70.9-0.90.6-1.1-0.5-0.70.70.3-0.20.40.2
Time to tail flick, test, after self-admin0.40.42.30.20.3-0.3-0.30.30.21.0-0.1-1.10.3-0.2-0.4-0.60.6-0.60.5-0.9-0.6-0.70.10.4-0.51.01.5
Delta time to tail flick, vehicle, before/after SA0.20.21.10.10.0-0.1-0.20.20.30.30.3-0.3-0.9-0.4-0.6-0.40.4-0.40.5-0.5-0.5-0.4-0.20.3-0.4-0.51.0
Delta time to tail flick, test, before/after SA0.60.52.7-0.3-0.30.20.2-0.2-0.30.40.4-0.5-0.4-0.6-0.8-0.80.7-0.70.9-0.8-1.0-0.80.30.8-1.01.11.6
Tibia length1.13.08.42.02.0-1.9-2.12.12.32.9-2.0-2.92.21.71.31.1-1.21.2-1.20.71.01.1-1.9-1.41.2-0.60.7
Ambulatory time before self-admin1.41.53.2-0.4-0.30.20.6-0.6-0.60.80.7-0.9-0.4-1.0-1.3-1.51.6-1.61.4-1.8-1.5-1.61.01.5-1.61.71.5
Ambulatory time after self-admin0.20.20.80.30.3-0.40.1-0.10.20.8-0.2-0.90.4-0.1-0.2-0.40.4-0.40.3-0.7-0.3-0.40.00.2-0.30.60.7
Bone: tissue strength0.20.20.60.50.5-0.5-0.40.40.20.1-0.3-0.00.30.30.40.5-0.40.4-0.50.50.50.4-0.2-0.30.4-0.3-0.7
Total heroin consumption1.51.72.9-1.6-1.51.61.7-1.7-1.4-1.31.51.3-1.4-1.5-1.4-1.51.2-1.21.5-1.5-1.4-1.20.60.5-0.50.00.4
Bone: trabecular number2.84.411.3-3.2-3.22.92.9-2.9-2.4-3.32.33.4-2.4-2.0-1.5-1.51.3-1.31.4-1.3-1.3-1.21.40.7-0.50.3-0.3
Bone: trabecular spacing0.60.82.51.41.3-1.3-1.51.50.91.5-0.8-1.60.90.70.40.6-0.30.3-0.50.60.40.3-0.4-0.0-0.10.00.3
Bone: trabecular thickness0.30.41.2-1.0-0.90.90.6-0.6-0.6-1.10.81.1-0.9-0.6-0.5-0.40.4-0.40.4-0.4-0.3-0.30.30.1-0.0-0.0-0.4
Bone: trabecular tissue density0.00.10.3-0.1-0.10.50.2-0.2-0.10.10.2-0.1-0.1-0.2-0.2-0.30.2-0.20.3-0.4-0.3-0.2-0.1-0.20.2-0.00.3
Water consumed over 24 hours1.31.62.2-1.3-1.21.31.2-1.2-1.3-1.11.51.0-1.5-1.4-1.5-1.41.3-1.31.4-1.2-1.4-1.31.01.3-1.30.80.9
Number of responses in last shaping day0.10.11.4-0.3-0.30.30.4-0.4-0.4-0.00.10.00.4-0.00.2-0.10.3-0.3-0.10.00.1-0.20.70.1-0.11.2-0.4