Hub : Genes

Agbl5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative TSS XM_063262056.1 0.02 0.02 9.8e-03 0.01 0.01 0.01 0.01 1.5e-02 1.4e-02 1.4e-02 1.6e-02
2 pVTA alternative TSS NM_001126372.1 0.03 0.02 9.3e-03 0.01 0.01 0.01 0.01 2.1e-02 3.3e-02 1.1e-01 2.5e-02
3 Adipose alternative TSS XM_063262056.1 0.02 0.03 6.8e-03 0.01 0.01 0.01 0.01 8.7e-03 9.6e-03 1.2e-02 1.1e-02
4 pVTA alternative TSS NM_001126372.1 0.03 0.02 8.9e-03 0.02 0.01 0.02 0.01 1.8e-02 2.1e-02 1.1e-02 2.4e-02
5 NAcc intron excision ratio chr6_31207681_31208417 0.02 0.02 2.4e-03 0.01 0.02 0.01 0.01 9.4e-03 1.1e-03 1.1e-02 4.0e-03
6 NAcc intron excision ratio chr6_31208580_31208884 0.02 0.02 1.7e-03 0.01 0.02 0.02 0.01 6.7e-03 6.4e-04 3.3e-04 2.6e-03
7 RMTg mRNA stability Agbl5 0.13 0.1 6.7e-03 0.06 0.03 0.04 0.04 1.3e-02 4.6e-02 2.9e-02 2.6e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density2.64.86.3-2.4-1.7-1.7-2.5-2.5-2.4-1.9
Area under the delay curve0.00.00.1-0.2-0.1-0.1-0.3-0.2-0.10.2
BMI with tail1.14.06.22.12.52.51.91.81.61.4
BMI without tail0.84.14.82.12.22.21.92.01.91.9
Body weight2.611.612.33.53.43.43.23.43.53.5
Weight adjusted by age0.00.10.60.20.30.3-0.0-0.1-0.4-0.7
Bone surface0.61.32.4-1.4-0.6-0.6-1.6-1.4-1.1-0.9
Bone volume1.12.13.3-1.7-1.1-1.1-1.8-1.7-1.5-0.9
Breakpoint value in progressive ratio session0.50.91.5-0.8-0.8-0.8-1.1-1.1-1.2-0.5
Number of licking bursts0.20.51.10.61.01.00.60.60.50.6
Context. condit. distance diff. score0.10.10.3-0.3-0.5-0.4-0.3-0.3-0.3-0.3
Locomotion velocity, session 10.40.40.70.50.70.80.60.50.70.8
Locomotion distance, session 10.40.50.9-0.9-0.4-0.3-0.9-1.0-0.6-0.4
Locomotion velocity, session 20.20.20.40.40.30.40.50.50.40.6
Locomotion distance, session 20.10.20.40.30.50.70.30.20.50.5
Locomotion velocity, session 30.50.51.6-0.4-0.2-0.2-0.5-0.7-1.0-1.3
Locomotion distance, session 30.10.10.2-0.10.40.5-0.3-0.4-0.3-0.4
Stereotopy head waving bouts, day 32.52.93.5-1.7-1.6-1.6-1.7-1.7-1.8-1.9
Stereotopy head waving duration, day 30.50.60.8-0.7-0.9-0.9-0.7-0.8-0.8-0.8
Locomotion velocity, session 70.20.20.6-0.40.00.1-0.6-0.6-0.8-0.3
Locomotion distance, session 70.50.61.40.71.11.20.40.40.21.0
Stereotopy head waving bouts, day 70.10.10.20.20.20.30.10.00.1-0.5
Stereotopy head waving duration, day 70.50.71.9-0.6-0.6-0.6-0.7-0.7-0.7-1.4
Locomotion velocity, session 80.40.50.6-0.8-0.8-0.6-0.8-0.7-0.6-0.6
Locomotion distance, session 80.20.30.4-0.6-0.5-0.4-0.6-0.6-0.4-0.3
Degree of sensitization distance0.91.01.70.90.80.90.91.00.91.3
Degree of sensitization stereotypy0.30.40.50.70.70.70.60.60.6-0.0
Conditioned locomotion4.04.75.1-2.2-2.3-2.3-2.1-2.1-2.1-2.2
Cocaine response after cond. corrected0.10.20.4-0.6-0.4-0.4-0.7-0.6-0.2-0.1
Cocaine response after cond. not corrected0.71.01.4-1.1-0.9-0.9-1.2-1.1-0.8-0.8
Cocaine response before conditioning2.83.34.3-1.8-1.8-1.8-1.6-1.6-1.9-2.1
Saline control response1.01.42.1-1.1-1.1-1.0-1.1-1.1-1.3-1.4
Bone: connectivity density2.13.34.6-1.9-1.3-1.2-2.2-2.1-2.0-1.7
Bone: cortical apparent density0.10.20.4-0.5-0.3-0.4-0.5-0.5-0.6-0.4
Bone: cortical area0.10.10.2-0.30.30.4-0.5-0.3-0.10.1
Bone: cortical porosity2.12.23.1-1.4-1.4-1.5-1.4-1.5-1.5-1.8
Bone: cortical porosity1.82.02.2-1.4-1.3-1.4-1.5-1.5-1.3-1.5
Bone: cortical thickness0.10.20.40.30.60.60.40.50.50.5
Bone: cortical thickness0.60.71.0-1.0-0.7-0.7-1.0-0.9-0.9-0.6
Bone: cortical tissue density0.10.10.3-0.4-0.2-0.3-0.4-0.4-0.5-0.2
Condit. Reinf. active minus inactive responses1.41.62.01.31.41.31.21.21.01.4
Condit. Reinf. active-inactive response ratio1.31.42.31.21.21.11.11.11.01.5
Condit. Reinf. active responses0.00.00.1-0.00.30.2-0.00.0-0.10.2
Condit. Reinf. inactive responses1.01.31.7-1.2-1.0-0.9-1.3-1.2-1.2-1.1
Incentive salience index mean0.10.20.40.30.60.50.20.20.20.6
Condit. Reinf. lever presses0.50.71.0-1.0-0.8-0.8-1.0-1.0-0.8-0.4
Condit. Reinf. active minus inactive responses2.33.68.8-1.6-1.4-1.4-1.6-1.8-1.9-3.0
Condit. Reinf. active-inactive response ratio0.91.45.0-0.9-0.8-0.8-0.8-1.0-1.1-2.2
Condit. Reinf. active responses1.82.65.5-1.4-1.1-1.1-1.5-1.7-1.8-2.3
Condit. Reinf. inactive responses0.50.71.2-0.9-0.5-0.5-1.0-1.1-1.0-0.5
Condit. Reinf. lever presses1.82.73.8-1.7-1.5-1.5-1.5-1.5-1.7-2.0
Condit. Reinf. lever reinforcers received1.82.55.6-1.4-1.1-1.1-1.4-1.6-1.7-2.4
Conditioned reinforcement - actives1.97.410.7-2.6-3.3-3.3-2.5-2.5-2.5-2.3
Conditioned reinforcement - inactives2.67.18.7-2.8-2.9-3.0-2.5-2.5-2.5-2.3
Conditioned locomotion1.42.13.2-1.3-1.8-1.8-1.2-1.3-1.3-1.4
Patch foraging indifference point 0 sec0.51.52.41.31.61.51.31.00.90.8
Patch foraging indifference point AUC0.10.20.4-0.5-0.1-0.1-0.5-0.6-0.3-0.4
Delay disc. indifference point, 0s delay2.22.55.51.41.11.11.51.71.72.4
Delay disc. indifference point, 16s delay0.00.00.10.00.10.1-0.1-0.00.0-0.3
Delay disc. indifference point, 2s delay0.20.20.40.40.40.40.30.40.50.7
Delay disc. indifference point, 24s delay1.01.62.1-1.4-1.5-1.5-1.3-1.2-1.1-1.0
Delay disc. indifference point, 4s delay0.10.10.40.10.20.20.00.10.20.6
Delay disc. indifference point, 8s delay0.00.00.1-0.2-0.3-0.3-0.2-0.2-0.2-0.0
Indifference point function ln k0.30.91.4-1.0-1.2-1.2-0.9-0.8-0.9-0.7
Indifference point function log k0.30.91.4-1.0-1.2-1.2-0.9-0.8-0.9-0.7
Patch foraging total patch changes 0 sec0.51.62.61.41.61.61.31.11.00.8
Patch foraging total patch changes 12 sec1.62.12.41.51.51.51.51.41.31.4
Patch foraging total patch changes 18 sec0.61.32.41.21.51.51.00.90.90.7
Patch foraging total patch changes 24 sec0.51.92.21.41.51.51.51.41.30.9
Patch foraging total patch changes 6 sec1.32.23.91.62.01.91.51.11.00.9
Patch foraging time to switch 0 sec0.00.20.40.50.60.60.30.40.30.1
Patch foraging water rate 0 sec0.10.40.7-0.6-0.8-0.8-0.5-0.6-0.4-0.6
Patch foraging water rate 12 sec0.10.40.80.60.10.00.80.90.90.7
Patch foraging water rate 18 sec0.10.20.8-0.4-0.9-0.9-0.20.00.1-0.0
Patch foraging water rate 24 sec0.50.71.21.00.40.41.11.10.80.9
Patch foraging water rate 6 sec0.20.30.60.3-0.3-0.30.50.60.80.6
Seeking ratio, delayed vs. immediate footshock0.10.10.20.30.50.50.20.20.30.1
Distance traveled before self-admin0.10.20.5-0.4-0.7-0.7-0.2-0.10.2-0.0
Distance traveled after self-admin1.11.93.31.20.80.81.41.51.71.8
Extensor digitorum longus weight3.212.617.9-3.5-2.8-2.8-3.8-3.8-3.6-4.2
Bone: elastic displacement1.41.82.7-1.3-1.5-1.6-1.2-1.2-1.5-0.9
Bone: elastic work0.81.01.2-1.1-1.0-1.1-1.0-1.0-1.1-0.6
Bone: endosteal estimation0.20.41.0-0.7-0.4-0.3-1.0-0.9-0.5-0.0
Bone: endosteal perimeter0.00.10.3-0.3-0.1-0.0-0.5-0.4-0.20.2
Epididymis fat weight11.859.566.88.27.57.57.87.87.67.5
Delta time in closed arm before/after self-admin0.10.10.30.40.50.50.20.20.3-0.1
Delta time in open arm before/after self-admin0.10.10.5-0.2-0.1-0.1-0.2-0.3-0.7-0.3
Diff in mean of infusions in LGA sessions0.10.10.20.40.50.50.20.0-0.10.2
Delay discount exponential model param0.10.20.30.50.40.40.60.50.40.1
Extinction: sum of active levers before priming0.30.40.8-0.5-0.5-0.5-0.7-0.7-0.9-0.5
Active lever presses in extinction session 61.31.32.0-1.1-1.2-1.2-1.2-1.3-1.4-0.7
Bone: final force0.00.00.1-0.00.20.3-0.2-0.1-0.10.3
Bone: final moment0.00.00.1-0.10.20.2-0.2-0.1-0.00.4
Food consumed during 24 hour testing period0.00.00.1-0.10.10.2-0.1-0.0-0.1-0.3
Glucose0.71.01.61.11.31.30.90.91.00.5
Heart weight2.23.55.41.71.41.51.81.92.32.2
Delay discount hyperbolic model param0.00.10.10.20.10.10.40.30.3-0.1
Intermittent access intake day 1-15 change0.10.61.1-0.8-1.0-1.1-0.7-0.6-0.2-0.7
Intermittent access intake escalation0.00.20.5-0.5-0.7-0.7-0.3-0.30.1-0.4
Intermittent access intake escalation 20.00.10.2-0.2-0.1-0.2-0.2-0.00.4-0.3
Intermitt. access day 1 inactive lever presses0.11.83.2-1.3-1.0-1.1-1.2-1.3-1.5-1.8
Intermitt. access day 15 inactive lever presses0.84.15.6-2.2-1.5-1.5-2.1-2.1-2.3-2.4
Intermitt. access escalation Index1.44.37.32.02.72.71.91.71.71.5
Intermittent access day 1 total infusions2.16.36.9-2.5-2.6-2.6-2.4-2.5-2.6-2.4
Intermittent access day 15 total infusions1.53.74.8-2.0-2.2-2.2-1.8-1.8-1.6-1.7
Intermittent access terminal intake (last 3 days)2.95.16.8-2.3-2.6-2.6-2.1-2.1-1.9-2.1
Intermittent access total infusions5.16.08.0-2.4-2.8-2.8-2.3-2.3-2.3-2.2
Intermittent access day 1 locomotion1.93.43.7-1.8-1.9-1.9-1.7-1.8-1.9-1.9
Intermittent access day 15 total locomotion0.20.71.2-0.8-1.0-1.0-0.6-0.7-0.8-1.1
Intermittent access total locomotion1.61.92.9-1.2-1.7-1.7-1.2-1.2-1.3-1.4
Intermittent access standard deviation0.52.42.6-1.6-1.6-1.6-1.5-1.6-1.5-1.5
Left kidney weight0.00.10.1-0.2-0.4-0.4-0.3-0.20.00.3
Right kidney weight0.21.12.31.00.60.70.91.11.41.5
Cocaine induced anxiety0.10.10.5-0.2-0.1-0.1-0.3-0.4-0.5-0.7
Post-drug Anxiety1.71.92.11.41.41.41.41.41.41.3
Baseline Anxiety2.74.56.42.01.91.92.22.12.22.5
Tail length0.10.72.40.60.20.20.60.81.11.5
Length with tail0.83.56.71.91.11.11.82.02.22.6
Length without tail0.21.12.11.10.90.90.80.91.01.4
Times rat made contact with spout1.11.31.8-1.1-0.8-0.8-1.2-1.2-1.4-1.3
Lifetime Intake5.46.88.7-2.6-3.0-2.9-2.4-2.4-2.5-2.2
Liver weight, left2.95.07.62.21.91.92.22.32.42.8
Liver weight, right6.010.413.53.22.52.53.53.53.43.7
Locomotor activity0.50.81.01.01.01.00.90.80.61.0
Locomotor testing distance0.10.10.40.30.60.60.2-0.0-0.2-0.1
Locomotor testing rearing0.31.02.4-0.7-0.5-0.5-0.9-1.1-1.5-1.3
Locomotion in novel chamber0.00.10.20.40.10.10.30.20.30.3
Locomotion in novel chamber post-restriction1.54.75.72.42.22.22.32.22.11.7
Fecal boli incidents, locomotor time 10.51.32.2-1.3-1.5-1.5-1.0-1.0-0.6-0.7
Change in fecal boli incidents, locomotor task4.14.36.72.11.91.92.12.11.92.6
Time >=10cm from walls, locomotor time 10.20.30.7-0.5-0.9-0.9-0.1-0.1-0.40.1
Bouts of movement, locomotor time 10.40.52.1-0.40.30.3-0.8-0.7-0.5-1.5
Total resting periods, locomotor time 10.50.51.8-0.40.20.2-0.9-0.8-0.5-1.3
Rest time, locomotor task time 10.10.20.30.50.50.50.40.30.40.5
Distance moved, locomotor task time 10.10.30.80.50.10.10.70.80.50.9
Vertical activity count, locomotor time 10.00.20.70.30.20.20.50.50.40.8
Time >=10cm from walls, locomotor time 20.51.32.3-1.2-1.5-1.5-1.2-1.0-0.8-0.7
Bouts of movement, locomotor time 20.10.40.60.60.80.80.50.60.8-0.2
Total resting periods, locomotor time 20.10.40.70.60.90.90.30.40.6-0.5
Rest time, locomotor task time 20.10.20.6-0.40.10.1-0.5-0.6-0.3-0.8
Distance moved, locomotor task time 20.20.20.80.2-0.2-0.20.40.60.30.9
Vertical activity count, locomotor time 20.10.10.5-0.0-0.4-0.40.00.2-0.00.7
Light reinforcement 10.52.04.0-1.3-0.3-0.3-1.8-1.7-1.5-2.0
Light reinforcement 20.91.93.0-1.5-1.0-1.0-1.7-1.5-1.2-1.6
Bone: marrow area0.20.41.0-0.7-0.4-0.3-1.0-0.9-0.5-0.1
Bone: maximum diameter0.10.30.8-0.60.00.1-0.9-0.8-0.4-0.2
Bone: maximum force0.00.00.1-0.2-0.00.0-0.3-0.3-0.30.0
Bone: maximum moment0.00.10.2-0.4-0.1-0.1-0.4-0.4-0.30.0
Mean time between licks in bursts0.52.93.81.61.31.31.91.91.82.0
Mean num. licks in bursts0.41.01.4-1.0-1.2-1.1-0.9-0.9-0.9-0.9
Cd content in liver0.00.00.10.20.30.30.10.00.3-0.0
Co content in liver5.46.47.6-2.8-2.5-2.5-2.7-2.6-2.4-2.1
Cu content in liver0.40.40.7-0.7-0.8-0.8-0.5-0.5-0.7-0.4
Fe content in liver1.82.23.6-1.4-1.5-1.5-1.3-1.6-1.9-1.0
K content in liver0.20.20.60.10.40.5-0.1-0.00.30.8
Mg content in liver0.20.20.50.10.50.5-0.2-0.10.20.7
Mn content in liver0.70.81.90.91.41.40.50.30.60.6
Na content in liver1.51.72.9-1.5-1.6-1.7-1.2-1.1-1.0-0.6
Rb content in liver0.20.20.40.40.60.50.20.10.30.6
Se content in liver0.20.20.40.60.60.60.40.30.3-0.0
Sr content in liver0.10.10.3-0.2-0.6-0.60.00.10.30.2
Zn content in liver1.01.12.31.00.90.91.01.01.01.5
Bone: minimum diameter0.40.81.60.81.01.00.60.70.71.2
Time in familiar zone, hab. session 11.01.11.81.01.11.10.80.91.01.3
Time in novel zone, hab. session 10.20.20.40.60.40.40.60.5-0.0-0.2
Total zone transitions, hab. session 10.10.10.3-0.3-0.2-0.2-0.5-0.4-0.6-0.3
Total locomotion distance, hab. session 10.40.60.9-0.8-1.0-0.9-0.8-0.7-0.6-0.1
Locomotion velocity, hab. session 11.11.62.2-1.5-1.5-1.4-1.4-1.2-1.1-0.7
Time in familiar zone, hab. session 20.10.20.40.40.60.60.20.30.1-0.1
Time in novel zone, hab. session 20.20.20.60.30.1-0.00.40.40.40.8
Total zone transitions, hab. session 20.20.20.70.40.70.90.10.20.40.3
Total locomotion distance, hab. session 20.10.10.40.20.60.70.10.10.30.0
Locomotion velocity, hab. session 20.00.10.20.00.40.5-0.1-0.10.1-0.2
Novel to familiar place preference ratio0.71.01.21.00.90.91.01.01.11.0
Novelty place preference1.11.51.71.31.11.11.31.31.31.2
Time in novel zone, NPP test1.21.51.71.31.11.11.31.31.21.2
Total zone transitions, NPP test0.91.31.7-1.2-1.0-0.9-1.3-1.3-1.0-1.2
Total locomotion distance, NPP test1.31.92.3-1.4-1.2-1.1-1.5-1.5-1.3-1.5
Locomotion velocity, NPP test2.02.83.4-1.8-1.4-1.3-1.8-1.8-1.6-1.8
Intraocular pressure4.77.68.72.92.52.52.92.92.72.8
Delta distance traveled before/after self-admin2.32.52.81.51.51.51.71.61.61.6
Delta ambulatory time before/after self-admin0.40.81.00.81.01.00.80.80.71.0
Parametrial fat weight16.538.842.86.36.36.36.36.56.55.3
Pavlov. Cond. lever latency0.70.91.31.00.60.61.21.11.00.9
Pavlov. Cond. magazine entry latency0.00.00.10.10.30.4-0.0-0.1-0.1-0.1
Pavlov. Cond. change in total contacts0.00.00.1-0.2-0.1-0.1-0.2-0.2-0.30.1
Pavlov. Cond. index score0.10.20.3-0.40.10.1-0.6-0.6-0.5-0.4
Pavlov. Cond. latency score0.10.10.3-0.30.20.2-0.5-0.5-0.4-0.4
Pavlov. Cond. lever contacts0.50.61.0-0.9-0.5-0.5-1.0-0.9-0.8-0.6
Pavlov. Cond. magazine entry number0.10.10.20.3-0.1-0.10.40.40.30.4
Pavlov. Cond. intertrial magazine entries2.12.53.2-1.7-1.8-1.8-1.5-1.5-1.6-1.2
Pavlov. Cond. lever-magazine prob. diff.0.50.61.0-0.8-0.4-0.4-1.0-1.0-1.0-0.8
Pavlov. Cond. response bias0.81.01.3-1.1-0.8-0.7-1.1-1.1-1.1-0.9
Pavlov. Cond. lever latency1.31.82.31.41.31.21.31.21.41.5
Pavlov. Cond. magazine entry latency0.10.10.2-0.3-0.2-0.2-0.3-0.2-0.4-0.5
Pavlov. Cond. change in total contacts0.20.61.3-0.7-0.6-0.5-0.7-0.7-0.9-1.1
Pavlov. Cond. index score0.71.11.7-1.1-1.0-1.0-1.0-1.0-1.1-1.3
Pavlov. Cond. latency score0.71.21.8-1.1-1.0-1.0-1.0-1.0-1.1-1.3
Pavlov. Cond. lever contacts0.81.21.6-1.1-1.0-1.0-1.1-1.0-1.2-1.3
Pavlov. Cond. magazine entry number0.00.00.10.20.10.10.10.00.20.3
Pavlov. Cond. intertrial magazine entries2.35.05.92.42.12.12.32.22.42.2
Pavlov. Cond. lever-magazine prob. diff.0.40.60.9-0.8-0.6-0.6-0.7-0.7-0.8-1.0
Pavlov. Cond. response bias1.31.82.4-1.4-1.3-1.2-1.3-1.2-1.5-1.5
Time in closed arm before self-admin0.30.60.80.80.70.70.60.70.90.8
Time in closed arm after self-admin0.80.91.21.10.90.90.91.01.00.7
Time in open arm before self-admin0.00.00.00.00.10.10.00.10.2-0.1
Time in open arm after self-admin0.60.71.2-0.9-0.6-0.6-0.8-1.0-1.1-0.9
Bone: periosteal estimation0.20.51.3-0.9-0.4-0.3-1.1-1.0-0.6-0.1
Bone: periosteal perimeter0.10.10.3-0.4-0.1-0.0-0.6-0.4-0.2-0.0
Bone: post-yield work1.22.12.7-1.4-1.5-1.4-1.4-1.5-1.4-1.6
Progressive ratio test 1 active lever presses2.44.35.5-2.0-2.3-2.3-2.0-1.9-2.2-1.6
Progressive ratio test 1 breakpoint2.54.45.5-2.0-2.3-2.4-2.0-1.9-2.2-1.6
Progressive ratio test 1 inactive lever presses3.08.09.7-2.9-3.1-3.1-2.7-2.6-2.9-2.5
Progressive ratio test 2 active lever presses2.12.95.2-1.7-2.3-2.3-1.4-1.4-1.4-1.1
Progressive ratio test 2 breakpoint2.02.64.8-1.6-2.2-2.2-1.3-1.3-1.3-1.0
Progressive ratio test 2 inactive lever presses1.54.86.2-2.2-2.5-2.5-2.1-2.0-2.1-2.0
Incentive Sensitization - Responses0.41.12.2-1.2-1.5-1.4-0.9-0.9-0.7-0.5
Incentive Sensitization - Breakpoint0.30.81.6-1.0-1.3-1.2-0.6-0.7-0.4-0.3
Sum of active levers in priming session hrs 5-60.20.10.40.20.60.60.10.00.10.4
Progressive ratio0.00.10.20.30.30.30.20.10.20.5
Food seeking constrained by brief footshock8.010.011.8-3.1-3.4-3.4-3.0-3.2-3.3-2.5
Seeking ratio, punishment vs. effort0.71.62.0-1.3-1.4-1.4-1.1-1.1-1.4-1.1
Retroperitoneal fat weight29.1130.1141.711.911.811.911.511.311.110.3
Reaction time number correct0.10.30.7-0.6-0.4-0.4-0.6-0.7-0.4-0.8
Reaction time mean minus median0.00.20.4-0.4-0.5-0.5-0.2-0.1-0.6-0.5
Reaction time mean minus median AUC0.00.00.10.1-0.0-0.00.20.3-0.1-0.1
Reaction time num false alarms1.11.94.11.32.02.01.11.00.90.8
Reaction time num false alarms AUC0.92.04.21.42.12.01.21.01.00.8
Reaction time trials correct on left0.10.30.7-0.6-0.4-0.4-0.6-0.7-0.4-0.8
Reaction time trials on left0.10.40.7-0.6-0.4-0.4-0.6-0.7-0.4-0.9
Reaction time mean0.20.41.30.4-0.1-0.10.60.90.61.2
Reaction time mean AUC0.10.31.10.3-0.2-0.10.50.80.51.1
Median of all reaction times0.40.61.90.5-0.0-0.00.70.90.81.4
Reaction time omissions0.00.10.20.10.50.5-0.0-0.1-0.30.0
Reaction time false alarm rate1.82.54.31.62.12.11.41.31.11.2
Reaction time premature initiation rate0.10.10.20.50.30.40.50.40.20.1
Reaction time premature initiations0.00.00.10.10.20.20.10.00.0-0.4
Std. dev. reaction times0.00.10.30.2-0.1-0.10.40.50.00.5
Reaction time trials completed0.10.40.7-0.6-0.4-0.4-0.6-0.7-0.4-0.9
Reaction time trials AUC0.10.51.1-0.7-0.5-0.5-0.7-0.8-0.5-1.0
Run reversals in cocaine runway, females0.20.20.7-0.5-0.8-0.8-0.2-0.2-0.20.0
Run reversals in cocaine runway, males0.60.61.0-0.8-1.0-1.0-0.6-0.6-0.8-0.5
Latency to leave start box in cocaine runway0.60.91.2-1.0-1.1-1.1-1.0-0.9-0.9-0.3
Latency to leave start box in cocaine runway, F0.10.20.3-0.5-0.5-0.5-0.4-0.4-0.4-0.0
Latency to leave start box in cocaine runway, M0.60.61.0-0.8-1.0-1.0-0.7-0.6-0.6-0.4
Std. dev. time between licks in bursts0.50.91.30.81.11.10.80.81.10.9
Total sessions with >9 infusions2.73.44.4-1.7-2.1-2.1-1.7-1.7-1.9-1.5
Short access day 1 total inactive lever presses5.310.512.1-3.5-3.2-3.2-3.2-3.2-3.3-3.0
Short access day 10 total inactive lever presses0.42.64.8-1.5-0.9-0.9-1.6-1.7-1.9-2.2
Short access day 1 total infusions3.97.89.5-2.8-2.9-2.8-2.7-2.8-3.1-2.5
Short access day 10 total infusions3.65.97.9-2.5-2.8-2.8-2.3-2.3-2.4-1.8
Short access total infusions2.94.15.5-2.0-2.3-2.3-1.9-1.9-2.0-1.6
Short access day 1 locomotion3.55.87.8-2.2-2.4-2.4-2.2-2.2-2.5-2.8
Short access day 10 total locomotion0.62.65.5-1.4-1.4-1.4-1.5-1.5-1.5-2.3
Short access total locomotion0.91.42.0-1.1-1.4-1.4-1.0-1.0-1.2-1.3
One hour access (0.3 mA shock)3.23.85.2-2.1-2.3-2.3-1.9-1.8-1.6-1.5
Compulsive drug intake2.13.14.11.52.02.01.61.51.81.7
One hour access (shock baseline)2.66.89.8-2.6-3.1-3.1-2.5-2.3-2.2-2.3
Social response proportion0.10.10.60.0-0.3-0.30.10.10.30.8
Social responses0.30.40.80.60.60.70.40.50.90.6
Social time0.10.10.30.2-0.1-0.10.20.30.50.4
Soleus weight3.410.112.3-3.3-2.8-2.7-3.5-3.4-3.0-3.3
Bone: stiffness0.00.10.20.20.40.40.10.10.1-0.2
Tibialis anterior weight1.96.611.0-2.5-1.7-1.7-2.9-2.9-2.6-3.3
Time to tail flick, vehicle, before self-admin0.20.20.50.5-0.0-0.00.70.60.50.2
Time to tail flick, vehicle, after self-admin1.93.94.92.11.81.82.22.11.91.9
Time to tail flick, test, before self-admin0.20.20.3-0.5-0.6-0.6-0.3-0.3-0.4-0.5
Time to tail flick, test, after self-admin0.60.61.1-0.8-1.0-1.0-0.8-0.6-0.4-0.3
Delta time to tail flick, vehicle, before/after SA0.70.71.20.81.11.10.60.70.60.8
Delta time to tail flick, test, before/after SA1.51.82.3-1.5-1.5-1.5-1.5-1.4-1.1-0.9
Tibia length1.85.08.32.11.71.72.22.32.42.9
Ambulatory time before self-admin0.10.20.4-0.4-0.7-0.7-0.4-0.20.1-0.3
Ambulatory time after self-admin0.71.02.00.80.60.61.01.11.31.4
Bone: tissue strength0.60.71.30.80.50.50.90.91.10.7
Total heroin consumption2.52.93.4-1.8-1.5-1.5-1.8-1.8-1.8-1.7
Bone: trabecular number2.03.85.3-2.2-1.7-1.7-2.3-2.2-2.0-1.3
Bone: trabecular spacing1.31.92.91.51.01.01.71.61.41.2
Bone: trabecular thickness0.30.40.7-0.8-0.5-0.5-0.8-0.8-0.70.0
Bone: trabecular tissue density0.40.70.9-1.0-0.9-0.9-0.8-0.7-0.8-0.9
Water consumed over 24 hours0.00.10.2-0.10.40.4-0.2-0.1-0.1-0.2
Number of responses in last shaping day1.31.73.0-1.4-1.7-1.7-1.3-1.0-1.1-0.5