Afmid

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc alternative polyA NM_001111366.1 0.37 0.19 5.2e-03 0.03 0.02 0.03 0.02 3.9e-04 4.4e-03 1.6e-04 1.4e-03
2 LHb gene expression Afmid 0.48 0.25 2.3e-04 0.09 0.09 0.1 0.03 4.7e-03 4.5e-03 2.0e-03 5.8e-02
3 Liver gene expression Afmid 0.51 0.13 0.0e+00 0.46 0.47 0.47 0.46 6.8e-57 5.9e-58 2.9e-58 2.4e-56
4 Liver isoform ratio XM_017597530.2 0.26 0.12 0.0e+00 0.32 0.32 0.32 0.32 2.5e-36 1.4e-35 5.8e-36 1.6e-36
5 OFC alternative polyA NM_001111366.1 0.16 0.15 9.7e-03 0.01 0.02 0.02 0.01 1.5e-01 8.7e-02 1.1e-01 1.5e-01
6 pVTA gene expression Afmid 0.22 0.14 8.6e-06 0.11 0.11 0.1 0.11 2.6e-05 2.3e-05 3.4e-05 1.4e-05
7 Liver isoform ratio XM_006247823.4 0.1 0.05 5.6e-17 0.13 0.14 0.13 0.13 3.1e-14 5.3e-15 1.0e-14 1.6e-14
8 PL gene expression Afmid 0.11 0.07 1.3e-12 0.13 0.12 0.12 0.12 9.5e-14 1.4e-12 3.6e-13 1.2e-13
9 Adipose gene expression Afmid 0.03 0.02 2.3e-04 0.03 0.03 0.02 0.02 5.3e-04 7.4e-04 3.9e-03 1.4e-03
10 NAcc gene expression Afmid 0.14 0.09 1.1e-16 0.15 0.12 0.14 0.15 2.8e-17 3.3e-14 3.7e-16 1.2e-16
11 Liver intron excision ratio chr10_103048741_103054305 0.04 0.04 1.5e-03 0.01 0.02 0.02 0.01 9.0e-03 5.3e-03 6.0e-03 1.5e-02
12 Liver alternative polyA XM_006247823.4 0.13 0.08 0.0e+00 0.16 0.15 0.15 0.15 7.2e-17 1.3e-16 9.5e-17 6.6e-16
13 Liver alternative polyA XM_006247823.4 0.13 0.08 0.0e+00 0.16 0.16 0.16 0.16 1.1e-17 1.4e-17 1.3e-17 3.9e-17
14 Liver alternative polyA XM_017597530.2 0.2 0.11 0.0e+00 0.2 0.2 0.2 0.2 1.2e-21 2.3e-21 2.3e-21 1.3e-21
15 Liver alternative polyA XM_017597530.2 0.18 0.1 0.0e+00 0.21 0.2 0.2 0.21 1.5e-22 2.4e-22 2.4e-22 1.7e-22
16 Brain gene expression Afmid 0.23 0.12 2.0e-10 0.1 0.11 0.1 0.11 3.3e-09 1.1e-10 8.3e-10 3.8e-10
17 Brain intron excision ratio chr10_103046270_103048651 0.05 0.06 2.1e-03 0.03 0.03 0.04 0.03 8.2e-04 3.7e-04 2.5e-04 5.6e-04
18 Brain alternative TSS NM_001111366.1 0.02 0.02 6.1e-03 0.02 0.01 0.02 0.02 2.5e-03 1.5e-02 4.8e-03 4.6e-03
19 BLA gene expression Afmid 0.19 0.1 2.0e-09 0.14 0.13 0.13 0.14 5.9e-08 3.0e-07 2.1e-07 7.7e-08
20 PL mRNA stability Afmid 0.06 0.05 7.1e-03 0.02 0.01 0.02 0.02 4.4e-03 2.2e-02 5.3e-03 6.7e-03
21 IL gene expression Afmid 0.36 0.24 4.8e-04 0.05 0.09 0.11 0.1 2.8e-02 3.6e-03 1.5e-03 2.2e-03
22 PL intron excision ratio chr10_103048741_103054305 0.02 0.02 9.2e-03 0.01 0 0 0.01 1.3e-02 1.9e-01 8.0e-02 4.7e-02
23 Liver isoform ratio NM_001111366.1 0.21 0.12 1.1e-08 0.07 0.08 0.07 0.07 1.6e-08 7.8e-09 1.1e-08 1.4e-08
24 NAcc intron excision ratio chr10_103054543_103056485 0.23 0.12 2.7e-03 0.04 0.03 0.03 0.03 2.2e-05 4.0e-04 6.5e-04 8.0e-05
25 NAcc intron excision ratio chr10_103056570_103056650 0.34 0.15 2.8e-04 0.04 0.04 0.03 0.04 7.0e-06 1.7e-05 2.5e-04 3.7e-05
26 LHb alternative polyA NM_001111366.1 0.53 0.2 2.3e-03 0.03 0.03 0.08 0.06 6.5e-02 6.4e-02 5.5e-03 1.7e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26
Bone: apparent density0.91.54.01.7-1.71.00.9-1.32.0-1.4-0.5-0.5-0.51.01.41.4-1.4-1.40.3-1.4-1.5-1.5-1.5-0.0-1.2-0.3-1.21.2-0.8
Area under the delay curve0.90.92.40.50.3-0.7-0.81.1-0.11.20.50.50.5-1.5-0.7-0.70.70.7-0.81.21.30.80.81.61.50.1-1.51.5-0.4
BMI with tail0.82.717.6-3.01.9-0.9-0.20.1-2.2-0.20.30.20.21.2-0.6-0.60.60.60.00.00.40.50.5-2.8-1.21.74.2-4.20.9
BMI without tail0.81.63.30.9-1.11.21.4-1.50.9-1.6-1.6-1.6-1.61.71.11.1-1.1-1.11.6-1.5-0.9-1.2-1.2-1.4-1.8-0.61.0-1.00.7
Body weight0.83.27.9-2.82.6-1.9-1.41.7-2.81.41.11.11.1-0.7-1.8-1.81.81.8-1.01.62.01.71.7-0.90.82.02.7-2.70.5
Weight adjusted by age0.10.10.50.4-0.2-0.3-0.20.10.40.10.30.30.3-0.2-0.4-0.40.40.4-0.50.10.10.40.40.6-0.20.5-0.50.5-0.7
Bone surface1.52.712.32.5-1.0-0.8-1.10.71.70.71.21.21.2-1.6-0.6-0.60.60.6-1.70.70.70.60.63.10.90.9-3.53.5-3.0
Bone volume0.91.57.12.5-1.4-0.1-0.3-0.22.0-0.20.50.50.5-0.50.10.1-0.1-0.1-0.80.0-0.0-0.1-0.12.0-0.10.5-2.72.7-2.4
Breakpoint value in progressive ratio session0.70.85.51.2-0.4-0.7-0.50.10.8-0.20.80.80.8-0.0-0.9-0.90.90.9-0.60.30.50.90.91.1-0.81.4-0.70.7-2.3
Number of licking bursts0.10.10.30.10.1-0.00.10.2-0.20.2-0.5-0.5-0.5-0.20.10.1-0.1-0.10.00.20.4-0.0-0.0-0.00.3-0.1-0.00.00.6
Context. condit. distance diff. score0.40.52.10.50.0-0.6-0.70.40.20.40.90.90.9-0.6-0.8-0.80.80.8-0.70.20.50.70.71.10.20.7-0.80.8-1.4
Locomotion velocity, session 10.40.51.7-1.31.0-0.4-0.50.8-1.21.00.20.10.1-0.8-0.2-0.20.20.2-0.41.00.50.30.3-0.11.3-0.20.3-0.31.2
Locomotion distance, session 12.53.24.70.4-1.21.92.1-1.90.9-1.9-2.1-2.2-2.22.01.91.9-1.9-1.92.1-1.5-1.9-1.7-1.7-2.0-1.7-1.71.2-1.22.0
Locomotion velocity, session 20.50.61.3-0.0-0.60.80.8-0.90.5-0.9-0.6-0.7-0.70.91.01.0-1.0-1.00.6-0.8-1.2-0.9-0.9-0.9-0.7-0.60.4-0.40.6
Locomotion distance, session 25.27.29.80.5-2.12.83.0-3.01.7-3.0-2.8-2.8-2.83.13.13.1-3.1-3.12.7-2.7-3.1-3.0-3.0-3.0-2.7-2.21.4-1.42.4
Locomotion velocity, session 30.20.21.6-0.10.10.30.20.2-0.30.4-0.5-0.4-0.4-0.40.40.4-0.4-0.40.40.40.1-0.1-0.1-0.00.8-1.0-0.10.11.3
Locomotion distance, session 30.70.73.1-0.90.50.40.7-0.4-0.8-0.4-0.5-0.6-0.60.80.60.6-0.6-0.60.9-0.6-0.2-0.4-0.4-1.6-0.4-0.41.8-1.81.6
Stereotopy head waving bouts, day 32.32.84.2-0.91.2-1.8-1.81.6-0.91.52.01.91.9-1.5-2.0-2.02.02.0-2.01.61.52.02.01.61.11.9-0.30.3-1.9
Stereotopy head waving duration, day 32.53.06.1-0.30.9-1.8-1.91.6-0.41.52.02.02.0-1.7-2.0-2.02.02.0-2.21.71.42.02.02.21.11.9-1.11.1-2.5
Locomotion velocity, session 70.30.31.61.3-0.80.50.4-0.30.9-0.2-0.4-0.4-0.4-0.10.40.4-0.4-0.40.4-0.4-0.2-0.4-0.40.60.1-0.8-1.11.1-0.2
Locomotion distance, session 72.53.25.32.3-2.21.91.9-2.12.2-2.1-1.7-1.5-1.51.91.91.9-1.9-1.91.8-2.2-1.7-2.0-2.0-0.9-2.0-1.4-0.50.50.0
Stereotopy head waving bouts, day 73.74.15.8-0.81.7-2.2-2.32.2-1.42.22.32.22.2-2.2-2.4-2.42.42.4-2.22.02.22.22.22.01.92.0-0.60.6-1.7
Stereotopy head waving duration, day 75.26.38.9-1.12.0-2.7-2.92.9-1.62.82.92.82.8-3.0-2.7-2.72.72.7-2.92.72.52.52.52.62.72.3-1.21.2-2.1
Locomotion velocity, session 80.60.72.80.8-0.1-0.5-0.80.70.30.80.70.70.7-1.2-0.5-0.50.50.5-1.00.50.60.50.51.61.10.2-1.71.7-1.0
Locomotion distance, session 81.92.94.91.5-2.01.91.9-2.21.9-2.2-1.6-1.6-1.62.11.71.7-1.7-1.71.8-2.1-1.9-1.7-1.7-1.2-2.2-1.30.1-0.10.2
Degree of sensitization distance3.73.710.33.2-3.01.91.6-2.03.2-2.0-1.6-1.4-1.41.31.71.7-1.7-1.71.3-1.8-1.9-1.9-1.90.5-1.7-1.5-2.22.2-1.0
Degree of sensitization stereotypy1.51.62.7-0.41.2-1.4-1.41.5-1.01.41.51.31.3-1.4-1.5-1.51.51.5-1.31.31.61.31.31.11.31.1-0.30.3-0.9
Conditioned locomotion0.20.20.60.6-0.70.50.6-0.50.8-0.6-0.7-0.7-0.70.50.10.1-0.1-0.10.5-0.3-0.5-0.2-0.2-0.0-0.5-0.3-0.20.2-0.0
Cocaine response after cond. corrected0.40.40.9-0.50.6-0.8-0.60.5-0.50.40.60.60.6-0.3-0.8-0.80.80.8-0.70.50.60.90.90.30.11.00.3-0.3-0.7
Cocaine response after cond. not corrected0.10.10.30.10.1-0.3-0.40.3-0.00.30.30.30.3-0.4-0.4-0.40.40.4-0.40.40.30.50.50.50.20.3-0.30.3-0.5
Cocaine response before conditioning0.60.72.21.3-1.10.80.4-0.41.1-0.2-0.5-0.5-0.5-0.21.01.0-1.0-1.00.4-0.4-0.7-0.9-0.90.70.3-1.2-1.51.50.1
Saline control response0.91.24.60.9-0.91.10.7-0.20.70.2-1.5-1.5-1.5-0.50.90.9-0.9-0.90.8-0.2-0.6-0.9-0.90.71.2-2.1-1.71.71.7
Bone: connectivity density1.62.55.62.2-2.11.41.2-1.42.4-1.4-0.9-0.9-0.90.81.91.9-1.9-1.90.6-1.7-1.8-1.9-1.90.2-1.0-1.1-1.91.9-0.4
Bone: cortical apparent density1.41.86.4-1.40.00.81.1-1.2-0.2-1.4-0.7-0.7-0.71.91.01.0-1.0-1.00.8-1.5-1.6-1.2-1.2-2.5-1.8-0.02.3-2.31.3
Bone: cortical area3.75.611.2-3.33.2-2.7-2.52.2-3.12.02.52.52.5-1.4-2.5-2.52.52.5-2.42.12.12.42.4-0.11.52.92.3-2.3-0.5
Bone: cortical porosity1.71.93.1-1.01.3-1.6-1.81.6-1.11.61.71.61.6-1.7-1.3-1.31.31.3-1.71.51.11.21.21.41.61.2-0.70.7-0.9
Bone: cortical porosity2.42.64.1-0.81.4-1.8-2.01.9-1.11.92.01.91.9-2.0-1.5-1.51.51.5-2.01.81.51.41.41.81.81.4-1.01.0-1.3
Bone: cortical thickness3.55.728.7-5.33.4-1.3-0.70.8-4.00.60.70.70.70.7-1.0-1.01.01.0-0.60.40.40.70.7-3.60.21.65.4-5.42.9
Bone: cortical thickness1.92.211.8-3.22.1-0.7-0.30.5-2.50.40.30.20.20.5-0.5-0.50.50.5-0.20.40.40.30.3-2.40.10.93.4-3.42.0
Bone: cortical tissue density1.31.86.1-1.3-0.10.81.1-1.3-0.1-1.4-0.7-0.7-0.71.91.11.1-1.1-1.10.8-1.6-1.6-1.3-1.3-2.5-1.8-0.02.2-2.21.2
Condit. Reinf. active minus inactive responses0.20.20.70.7-0.80.50.4-0.40.9-0.4-0.3-0.5-0.50.10.30.3-0.3-0.30.3-0.4-0.5-0.5-0.50.3-0.2-0.6-0.80.8-0.1
Condit. Reinf. active-inactive response ratio0.50.52.21.1-1.10.30.1-0.51.4-0.50.20.10.10.00.30.3-0.3-0.3-0.3-0.5-0.8-0.4-0.40.9-0.4-0.0-1.51.5-1.2
Condit. Reinf. active responses0.81.02.20.7-1.21.31.2-0.91.0-0.8-1.2-1.4-1.40.60.90.9-0.9-0.91.2-0.7-1.1-1.0-1.0-0.3-0.4-1.5-0.50.51.0
Condit. Reinf. inactive responses1.31.53.40.6-1.01.51.6-1.10.6-0.9-1.8-1.9-1.91.01.01.0-1.0-1.01.8-0.6-0.9-1.1-1.1-1.0-0.5-1.80.4-0.41.9
Incentive salience index mean0.10.10.60.5-0.60.40.2-0.20.6-0.1-0.3-0.4-0.4-0.10.10.1-0.1-0.10.2-0.1-0.3-0.3-0.30.40.1-0.6-0.70.70.1
Condit. Reinf. lever presses0.10.20.60.2-0.50.50.5-0.30.4-0.3-0.8-0.8-0.80.20.10.1-0.1-0.10.60.0-0.3-0.4-0.4-0.2-0.1-0.7-0.10.10.6
Condit. Reinf. active minus inactive responses0.40.41.70.6-0.0-0.3-0.70.60.10.70.50.50.5-0.9-0.3-0.30.30.3-0.50.70.40.40.41.30.8-0.1-1.31.3-0.8
Condit. Reinf. active-inactive response ratio0.10.10.70.30.0-0.1-0.30.40.00.50.10.10.1-0.6-0.1-0.10.10.1-0.20.40.20.10.10.70.6-0.3-0.80.80.0
Condit. Reinf. active responses0.20.31.11.1-0.80.2-0.0-0.30.9-0.30.0-0.0-0.0-0.00.30.3-0.3-0.3-0.0-0.1-0.4-0.2-0.20.7-0.3-0.2-1.01.0-1.0
Condit. Reinf. inactive responses0.60.71.61.1-1.20.90.7-1.01.3-1.0-0.6-0.6-0.60.70.90.9-0.9-0.90.6-0.8-1.0-0.8-0.80.0-0.9-0.6-0.60.6-0.5
Condit. Reinf. lever presses1.11.43.51.6-1.81.31.1-1.41.9-1.3-1.1-1.1-1.10.91.21.2-1.2-1.20.9-1.1-1.5-1.2-1.20.2-1.2-1.0-1.11.1-0.4
Condit. Reinf. lever reinforcers received0.20.31.71.2-0.90.20.0-0.51.0-0.60.0-0.0-0.00.30.30.3-0.3-0.30.0-0.3-0.5-0.3-0.30.6-0.70.0-0.80.8-1.3
Conditioned reinforcement - actives0.70.71.40.6-0.70.80.9-1.00.6-1.1-0.8-0.9-0.91.10.80.8-0.8-0.81.1-0.9-0.7-0.8-0.8-1.0-1.2-0.50.5-0.50.4
Conditioned reinforcement - inactives0.30.30.8-0.90.9-0.6-0.60.6-0.90.60.70.70.7-0.4-0.5-0.50.50.5-0.50.30.50.50.5-0.20.50.50.7-0.70.2
Conditioned locomotion0.70.92.50.7-0.90.90.9-1.20.9-1.3-0.8-0.8-0.81.40.80.8-0.8-0.81.0-1.1-0.9-0.8-0.8-1.0-1.6-0.30.6-0.60.0
Patch foraging indifference point 0 sec0.81.32.31.4-1.51.41.3-1.51.4-1.5-1.3-1.3-1.31.30.90.9-0.9-0.91.5-1.0-1.1-0.8-0.8-0.4-1.4-1.2-0.10.1-0.1
Patch foraging indifference point AUC2.63.05.51.7-1.82.01.7-1.61.8-1.4-2.1-2.2-2.21.11.91.9-1.9-1.91.9-1.6-1.7-1.9-1.9-0.5-0.8-2.3-1.21.21.6
Delay disc. indifference point, 0s delay0.80.82.8-1.21.1-0.9-1.01.3-1.11.40.80.80.8-1.3-0.7-0.70.70.7-1.00.80.80.80.80.61.70.2-0.10.10.4
Delay disc. indifference point, 16s delay0.40.41.21.1-0.90.70.7-0.60.9-0.6-0.7-0.8-0.80.40.60.6-0.6-0.60.6-0.5-0.2-0.6-0.60.2-0.5-0.6-0.80.8-0.0
Delay disc. indifference point, 2s delay0.30.31.00.60.1-0.3-0.40.60.10.70.20.20.2-0.9-0.1-0.10.10.1-0.31.00.90.30.30.90.9-0.0-1.01.0-0.3
Delay disc. indifference point, 24s delay0.10.10.40.1-0.30.30.2-0.20.4-0.1-0.4-0.4-0.4-0.00.20.2-0.2-0.20.1-0.3-0.3-0.2-0.20.30.1-0.4-0.70.70.3
Delay disc. indifference point, 4s delay0.80.92.60.00.6-0.7-0.91.2-0.41.40.60.60.6-1.5-0.7-0.70.70.7-0.91.21.20.80.81.41.60.1-1.21.2-0.2
Delay disc. indifference point, 8s delay2.93.06.60.01.2-1.6-1.82.1-0.92.31.41.41.4-2.6-1.6-1.61.61.6-1.72.12.21.71.72.42.60.7-1.81.8-0.8
Indifference point function ln k1.21.77.4-2.11.5-1.1-0.70.4-1.70.11.21.31.30.5-0.8-0.80.80.8-0.80.50.60.90.9-1.5-0.62.02.7-2.7-0.4
Indifference point function log k1.21.77.4-2.11.5-1.1-0.70.4-1.70.11.21.31.30.5-0.8-0.80.80.8-0.80.50.60.90.9-1.5-0.62.02.7-2.7-0.4
Patch foraging total patch changes 0 sec1.11.73.11.4-1.71.61.5-1.71.6-1.8-1.4-1.4-1.41.61.11.1-1.1-1.11.7-1.2-1.4-1.1-1.1-0.6-1.7-1.3-0.10.10.0
Patch foraging total patch changes 12 sec4.15.39.01.9-2.42.82.6-2.62.1-2.4-2.8-2.8-2.82.22.32.3-2.3-2.33.0-2.3-2.3-2.2-2.2-1.3-1.9-2.9-0.30.31.6
Patch foraging total patch changes 18 sec3.34.212.03.5-2.92.31.9-2.03.0-1.9-2.4-2.4-2.41.31.61.6-1.6-1.62.2-1.6-1.5-1.7-1.70.6-1.5-2.3-2.32.30.1
Patch foraging total patch changes 24 sec0.60.74.51.6-0.90.4-0.0-0.01.10.2-0.3-0.3-0.3-0.6-0.4-0.40.40.40.30.20.10.30.31.70.6-0.9-2.12.1-0.6
Patch foraging total patch changes 6 sec1.92.95.21.2-1.81.91.9-1.91.6-1.8-2.2-2.3-2.31.71.61.6-1.6-1.61.9-1.9-1.8-1.7-1.7-1.1-1.6-1.8-0.20.21.3
Patch foraging time to switch 0 sec0.20.40.6-0.40.6-0.7-0.60.8-0.60.80.70.70.7-0.8-0.6-0.60.60.6-0.60.50.80.50.50.50.80.5-0.10.1-0.3
Patch foraging water rate 0 sec0.81.22.71.6-1.51.41.2-1.21.4-1.2-1.5-1.4-1.40.90.90.9-0.9-0.91.4-0.8-0.9-0.7-0.7-0.0-0.9-1.4-0.70.70.3
Patch foraging water rate 12 sec0.50.85.0-1.50.6-0.20.2-0.4-0.7-0.70.00.10.11.2-0.4-0.40.40.40.1-0.7-0.30.30.3-1.6-1.20.92.2-2.20.1
Patch foraging water rate 18 sec0.20.21.00.7-0.60.30.3-0.60.6-0.8-0.2-0.2-0.20.70.20.2-0.2-0.20.1-0.6-0.3-0.3-0.3-0.3-1.00.30.2-0.2-0.5
Patch foraging water rate 24 sec1.52.04.92.2-2.01.51.6-1.72.0-1.8-1.8-1.7-1.71.51.11.1-1.1-1.11.6-1.6-1.1-1.1-1.1-0.4-1.8-1.0-0.50.5-0.1
Patch foraging water rate 6 sec0.40.53.4-1.30.60.00.2-0.2-0.9-0.3-0.3-0.3-0.30.8-0.1-0.10.10.10.3-0.1-0.20.20.2-1.3-0.50.31.9-1.90.9
Seeking ratio, delayed vs. immediate footshock0.30.31.00.0-0.30.70.4-0.40.3-0.2-0.3-0.2-0.20.20.80.8-0.8-0.80.5-0.4-0.6-0.9-0.9-0.40.1-1.0-0.20.20.8
Distance traveled before self-admin0.70.72.1-0.40.7-0.7-0.91.2-0.81.30.90.90.9-1.3-0.7-0.70.70.7-0.81.11.00.60.60.91.40.1-0.50.5-0.3
Distance traveled after self-admin1.21.34.02.0-1.71.11.0-1.41.9-1.5-0.9-0.9-0.91.10.90.9-0.9-0.90.9-1.2-1.2-1.0-1.00.1-1.4-0.6-1.01.0-0.8
Extensor digitorum longus weight1.24.78.20.5-1.62.22.5-2.41.1-2.5-2.4-2.5-2.52.82.02.0-2.0-2.02.6-2.1-2.0-2.1-2.1-2.9-2.4-1.52.0-2.02.1
Bone: elastic displacement1.51.75.9-1.60.20.81.1-1.0-0.5-1.1-0.8-0.7-0.71.61.21.2-1.2-1.20.9-1.2-1.4-0.9-0.9-2.4-1.1-0.42.3-2.31.7
Bone: elastic work1.21.57.3-2.71.8-1.1-0.70.7-1.90.50.91.01.00.1-0.8-0.80.80.8-0.90.40.40.90.9-1.30.21.52.4-2.40.5
Bone: endosteal estimation2.24.721.03.2-1.0-1.3-1.71.01.80.81.71.71.7-1.8-1.6-1.61.61.6-1.71.61.71.71.73.90.71.6-3.63.6-4.6
Bone: endosteal perimeter4.910.227.21.90.4-2.9-3.22.80.42.63.13.13.1-3.6-2.9-2.92.92.9-3.53.13.13.13.15.22.72.8-4.14.1-4.9
Epididymis fat weight0.20.62.5-0.80.9-0.7-0.30.3-0.90.10.30.40.40.3-0.6-0.60.60.6-0.20.40.70.90.9-0.7-0.61.21.6-1.6-0.4
Delta time in closed arm before/after self-admin0.70.73.01.1-0.3-0.4-0.50.60.60.60.50.40.4-1.0-0.5-0.50.50.5-0.50.50.60.60.61.70.60.1-1.71.7-1.2
Delta time in open arm before/after self-admin1.31.32.00.7-0.91.31.2-1.10.8-1.1-1.3-1.2-1.21.01.31.3-1.3-1.31.2-1.1-1.0-1.4-1.4-1.0-0.6-1.30.1-0.11.3
Diff in mean of infusions in LGA sessions1.31.46.10.9-0.1-1.1-1.00.70.40.41.01.11.1-0.7-1.4-1.41.41.4-1.11.11.11.31.31.8-0.11.6-1.01.0-2.5
Delay discount exponential model param1.11.22.9-0.5-0.50.81.0-1.30.3-1.4-0.7-0.7-0.71.70.80.8-0.8-0.80.9-1.4-1.5-0.9-0.9-1.7-1.6-0.31.6-1.60.5
Extinction: sum of active levers before priming0.10.10.7-0.70.4-0.3-0.20.1-0.4-0.00.10.10.10.2-0.3-0.30.30.3-0.20.1-0.10.30.3-0.4-0.10.50.8-0.80.1
Active lever presses in extinction session 60.10.10.60.0-0.30.00.2-0.40.4-0.5-0.3-0.3-0.30.5-0.1-0.10.10.10.0-0.2-0.50.20.2-0.1-0.80.40.2-0.2-0.5
Bone: final force1.62.67.6-2.82.2-1.9-1.81.6-2.11.41.71.71.7-1.0-1.7-1.71.71.7-1.91.21.01.41.40.11.01.91.2-1.2-0.3
Bone: final moment1.82.97.9-2.82.2-2.0-1.91.6-2.11.51.91.81.8-1.1-1.9-1.91.91.9-2.01.21.01.51.50.21.12.11.2-1.2-0.4
Food consumed during 24 hour testing period0.60.73.91.4-1.00.50.2-0.11.10.1-0.7-0.7-0.7-0.60.20.2-0.2-0.20.1-0.2-0.2-0.3-0.31.30.7-1.0-2.02.00.0
Glucose0.20.31.7-0.60.8-0.6-0.30.2-0.80.00.30.30.30.30.00.0-0.0-0.0-0.3-0.30.5-0.1-0.1-1.0-0.51.01.3-1.30.2
Heart weight1.11.56.7-2.11.7-1.0-0.60.6-1.80.30.90.90.90.3-0.9-0.90.90.9-0.40.60.80.90.9-1.4-0.31.52.6-2.60.2
Delay discount hyperbolic model param1.01.02.5-0.5-0.40.80.9-1.20.2-1.3-0.6-0.6-0.61.60.70.7-0.7-0.70.8-1.4-1.5-0.9-0.9-1.6-1.5-0.21.5-1.50.5
Intermittent access intake day 1-15 change0.20.21.10.00.20.1-0.10.4-0.30.6-0.0-0.0-0.0-0.60.20.2-0.2-0.20.00.20.3-0.2-0.20.21.0-0.7-0.50.50.9
Intermittent access intake escalation0.30.21.10.7-0.30.30.10.10.30.3-0.2-0.2-0.2-0.50.40.4-0.4-0.40.2-0.00.1-0.4-0.40.50.8-0.9-1.01.00.5
Intermittent access intake escalation 20.50.41.30.8-0.60.80.7-0.30.5-0.2-0.7-0.8-0.80.00.80.8-0.8-0.80.7-0.5-0.2-0.8-0.8-0.00.3-1.1-0.60.60.9
Intermitt. access day 1 inactive lever presses2.02.13.1-0.81.4-1.6-1.71.7-1.21.71.81.71.7-1.7-1.5-1.51.51.5-1.71.51.51.51.51.31.61.3-0.40.4-1.0
Intermitt. access day 15 inactive lever presses0.40.40.80.9-0.70.80.7-0.60.6-0.5-0.8-0.8-0.80.40.80.8-0.8-0.80.7-0.5-0.3-0.8-0.8-0.3-0.3-0.9-0.30.30.6
Intermitt. access escalation Index0.90.82.80.50.0-0.6-0.90.80.20.90.70.70.7-1.2-0.7-0.70.70.7-1.00.70.60.70.71.71.10.3-1.61.6-0.9
Intermittent access day 1 total infusions0.40.51.6-0.60.6-0.8-0.60.3-0.50.10.70.70.70.1-0.8-0.80.80.8-0.50.50.50.80.8-0.2-0.41.20.9-0.9-0.9
Intermittent access day 15 total infusions0.10.10.30.4-0.1-0.1-0.20.10.20.20.30.20.2-0.3-0.1-0.10.10.1-0.10.10.10.10.10.50.20.0-0.60.6-0.4
Intermittent access terminal intake (last 3 days)0.20.20.50.20.2-0.5-0.50.5-0.10.40.60.50.5-0.5-0.5-0.50.50.5-0.40.50.60.50.50.60.40.4-0.40.4-0.7
Intermittent access total infusions0.30.31.0-0.10.3-0.6-0.60.4-0.20.20.70.70.7-0.2-0.7-0.70.70.7-0.50.40.40.70.70.4-0.00.80.1-0.1-1.0
Intermittent access day 1 locomotion0.30.31.40.3-0.50.40.5-0.80.6-0.9-0.3-0.4-0.40.90.30.3-0.3-0.30.5-0.7-0.6-0.3-0.3-0.5-1.20.10.4-0.4-0.4
Intermittent access day 15 total locomotion0.20.20.5-0.40.6-0.4-0.40.2-0.50.10.60.60.60.0-0.4-0.40.40.4-0.20.30.40.40.4-0.3-0.10.60.7-0.7-0.4
Intermittent access total locomotion0.10.20.80.2-0.20.20.3-0.50.2-0.6-0.1-0.2-0.20.70.20.2-0.2-0.20.4-0.4-0.3-0.2-0.2-0.6-0.90.20.6-0.6-0.2
Intermittent access standard deviation3.94.17.0-1.42.3-2.3-2.22.4-2.22.32.22.22.2-2.1-2.2-2.22.22.2-2.02.42.72.22.21.02.02.00.5-0.5-0.9
Left kidney weight2.98.211.3-2.73.3-3.3-3.13.2-3.23.12.92.92.9-2.7-3.4-3.43.43.4-2.82.93.13.33.31.62.52.90.8-0.8-1.2
Right kidney weight1.23.46.4-2.42.5-2.0-2.02.0-2.51.91.81.81.8-1.4-2.0-2.02.02.0-1.61.91.81.91.90.21.61.81.5-1.5-0.1
Cocaine induced anxiety0.30.41.5-0.10.3-0.4-0.60.7-0.20.90.40.40.4-1.1-0.4-0.40.40.4-0.70.30.40.40.41.01.2-0.1-1.01.00.1
Post-drug Anxiety0.40.41.81.0-0.70.50.4-0.10.70.0-0.6-0.5-0.5-0.30.50.5-0.5-0.50.3-0.4-0.1-0.5-0.50.80.4-0.9-1.31.30.2
Baseline Anxiety0.10.10.5-0.30.20.00.2-0.2-0.2-0.2-0.1-0.1-0.10.40.10.1-0.1-0.10.2-0.00.0-0.1-0.1-0.5-0.30.10.7-0.70.1
Tail length0.51.66.32.5-1.81.21.0-0.81.8-0.6-1.4-1.3-1.30.00.90.9-0.9-0.91.1-0.8-0.5-1.0-1.01.1-0.1-1.6-2.22.20.2
Length with tail0.83.04.9-0.81.6-1.8-1.82.1-1.52.21.41.51.5-2.2-2.0-2.02.02.0-1.72.12.21.91.91.82.21.1-0.70.7-0.6
Length without tail4.18.914.2-3.73.8-3.4-3.13.2-3.73.13.13.13.1-2.5-3.3-3.33.33.3-3.03.13.03.23.20.82.63.01.7-1.7-0.9
Times rat made contact with spout0.50.51.31.1-0.90.70.6-0.61.0-0.5-0.8-0.8-0.80.30.80.8-0.8-0.80.6-0.6-0.5-0.8-0.80.0-0.3-0.8-0.80.80.2
Lifetime Intake0.40.51.2-0.50.6-0.8-0.80.5-0.50.40.90.80.8-0.3-0.8-0.80.80.8-0.70.40.50.90.90.30.11.10.4-0.4-1.0
Liver weight, left2.74.26.0-1.52.1-2.4-2.32.4-1.92.32.32.32.3-2.2-2.2-2.22.22.2-2.42.02.32.32.31.61.92.2-0.10.1-1.3
Liver weight, right0.91.53.5-1.81.7-1.3-1.11.4-1.91.40.90.90.9-1.1-1.2-1.21.21.2-1.01.41.31.31.30.11.31.11.0-1.00.3
Locomotor activity0.00.00.2-0.3-0.10.10.1-0.20.1-0.20.10.10.10.20.20.2-0.2-0.20.00.2-0.4-0.1-0.1-0.2-0.20.00.1-0.1-0.1
Locomotor testing distance0.20.32.30.5-0.4-0.3-0.3-0.00.7-0.10.70.70.7-0.1-0.1-0.10.10.1-0.60.2-0.20.20.20.8-0.40.6-0.80.8-1.5
Locomotor testing rearing1.01.62.61.3-1.61.41.3-1.41.6-1.3-1.0-1.0-1.01.01.61.6-1.6-1.61.1-1.1-1.5-1.4-1.4-0.3-1.0-1.3-0.90.90.2
Locomotion in novel chamber1.31.76.52.6-1.91.10.8-0.82.0-0.7-1.0-1.1-1.10.11.01.0-1.0-1.00.6-0.8-0.8-1.1-1.11.1-0.2-1.2-2.42.4-0.3
Locomotion in novel chamber post-restriction0.50.72.61.1-0.5-0.4-0.50.30.80.20.60.50.5-0.6-0.6-0.60.60.6-0.80.20.20.60.61.60.30.5-1.61.6-1.5
Fecal boli incidents, locomotor time 10.20.31.50.7-0.60.30.4-0.70.7-0.9-0.1-0.2-0.20.80.20.2-0.2-0.20.3-0.4-0.4-0.2-0.2-0.3-1.20.40.3-0.3-0.7
Change in fecal boli incidents, locomotor task0.10.10.5-0.50.00.20.3-0.3-0.2-0.3-0.2-0.2-0.20.50.20.2-0.2-0.20.4-0.1-0.3-0.0-0.0-0.7-0.4-0.00.6-0.60.3
Time >=10cm from walls, locomotor time 10.40.42.51.2-0.60.1-0.20.10.70.20.20.20.2-0.60.20.2-0.2-0.2-0.3-0.00.1-0.1-0.11.10.5-0.3-1.61.6-0.7
Bouts of movement, locomotor time 10.30.31.9-0.80.7-0.10.1-0.0-0.7-0.1-0.1-0.0-0.00.40.10.1-0.1-0.10.30.1-0.0-0.2-0.2-1.1-0.30.21.4-1.40.8
Total resting periods, locomotor time 10.30.31.6-0.50.50.00.2-0.2-0.6-0.2-0.1-0.1-0.10.50.30.3-0.3-0.30.3-0.0-0.0-0.4-0.4-1.2-0.40.11.3-1.30.7
Rest time, locomotor task time 10.60.72.0-1.31.2-0.9-0.60.5-1.20.40.90.90.9-0.0-0.7-0.70.70.7-0.60.60.50.50.5-0.7-0.11.21.4-1.4-0.3
Distance moved, locomotor task time 10.50.51.30.9-1.00.80.6-0.50.9-0.3-0.8-0.8-0.80.00.60.6-0.6-0.60.5-0.6-0.5-0.6-0.60.50.1-1.1-1.11.10.4
Vertical activity count, locomotor time 11.92.03.61.8-1.71.71.6-1.31.5-1.2-1.8-1.8-1.80.91.61.6-1.6-1.61.7-1.0-0.7-1.3-1.3-0.3-0.7-1.9-0.80.80.9
Time >=10cm from walls, locomotor time 20.40.51.1-0.6-0.10.50.5-0.5-0.1-0.5-0.5-0.5-0.50.60.90.9-0.9-0.90.4-0.9-0.9-0.9-0.9-1.0-0.3-0.50.6-0.61.0
Bouts of movement, locomotor time 20.30.41.00.20.3-0.7-0.70.5-0.10.40.80.80.8-0.4-0.7-0.70.70.7-0.70.50.50.60.60.60.20.8-0.30.3-1.0
Total resting periods, locomotor time 20.40.41.70.40.2-0.7-0.70.50.10.40.90.90.9-0.5-0.7-0.70.70.7-0.70.50.60.60.60.80.10.9-0.50.5-1.3
Rest time, locomotor task time 21.11.25.10.70.4-1.2-1.10.8-0.00.61.41.41.4-0.7-1.2-1.21.21.2-1.01.21.21.01.01.20.11.5-0.50.5-2.3
Distance moved, locomotor task time 20.70.84.0-1.50.40.60.7-0.4-0.7-0.2-0.8-0.8-0.80.60.80.8-0.8-0.80.7-0.5-0.7-0.5-0.5-1.40.0-0.91.3-1.32.0
Vertical activity count, locomotor time 20.40.51.4-0.50.00.60.8-0.5-0.3-0.5-0.8-0.7-0.70.70.60.6-0.6-0.61.0-0.2-0.1-0.2-0.2-1.2-0.5-0.61.2-1.21.1
Light reinforcement 12.03.65.91.1-1.72.32.2-2.11.3-2.0-2.4-2.4-2.42.02.02.0-2.0-2.02.4-1.8-1.8-1.8-1.8-1.6-1.6-2.20.6-0.61.8
Light reinforcement 20.30.42.00.2-0.20.80.7-0.4-0.1-0.2-1.1-1.1-1.10.30.50.5-0.5-0.51.0-0.4-0.1-0.3-0.3-0.40.2-1.20.3-0.31.4
Bone: marrow area2.24.821.03.2-1.0-1.3-1.71.01.80.81.81.71.7-1.8-1.6-1.61.61.6-1.71.61.71.71.74.00.81.6-3.63.6-4.6
Bone: maximum diameter6.812.516.9-0.92.6-4.0-4.13.7-2.03.44.14.14.1-3.7-3.9-3.93.93.9-4.13.83.83.83.83.73.03.9-1.41.4-3.9
Bone: maximum force1.83.16.1-2.32.1-2.1-2.01.6-1.91.32.02.02.0-1.0-2.0-2.02.02.0-2.11.31.31.81.80.40.72.51.1-1.1-1.1
Bone: maximum moment1.93.36.7-2.32.1-2.2-2.11.6-1.91.42.22.22.2-1.1-2.0-2.02.02.0-2.21.31.31.91.90.50.82.61.1-1.1-1.3
Mean time between licks in bursts0.10.10.8-0.90.3-0.2-0.10.1-0.40.10.30.30.30.00.20.2-0.2-0.2-0.2-0.2-0.4-0.4-0.4-0.5-0.00.20.5-0.50.2
Mean num. licks in bursts0.40.41.00.6-0.80.70.6-0.90.9-0.9-0.3-0.3-0.30.80.60.6-0.6-0.60.6-0.9-1.0-0.7-0.7-0.4-1.0-0.5-0.20.2-0.3
Cd content in liver1.11.24.8-1.00.30.50.8-0.8-0.5-0.9-0.6-0.5-0.51.40.90.9-0.9-0.90.7-1.0-0.7-0.9-0.9-2.2-1.20.02.1-2.11.2
Co content in liver0.30.31.00.3-0.40.40.4-0.80.4-0.9-0.2-0.2-0.20.90.30.3-0.3-0.30.4-1.0-0.7-0.5-0.5-0.7-1.00.00.6-0.6-0.3
Cu content in liver0.10.10.5-0.60.4-0.1-0.10.1-0.50.10.00.00.00.1-0.4-0.40.40.40.00.30.10.40.4-0.30.20.10.7-0.70.3
Fe content in liver0.50.63.41.4-0.80.0-0.20.21.00.20.10.10.1-0.7-0.4-0.40.40.4-0.30.30.10.20.21.60.6-0.2-1.91.9-1.1
K content in liver0.10.10.90.3-0.30.30.1-0.10.40.0-0.00.00.0-0.20.30.3-0.3-0.3-0.0-0.2-0.4-0.1-0.10.60.4-0.6-0.90.90.0
Mg content in liver1.41.43.00.8-1.41.41.2-1.41.4-1.4-1.0-1.0-1.01.21.31.3-1.3-1.30.8-1.6-1.7-1.4-1.4-0.7-1.1-1.0-0.40.40.3
Mn content in liver0.60.61.5-0.50.7-0.7-0.71.0-0.61.10.50.50.5-1.2-0.8-0.80.80.8-0.90.80.90.90.91.01.20.4-0.60.6-0.0
Na content in liver0.40.41.5-0.10.2-0.4-0.60.6-0.00.70.60.60.6-1.0-0.5-0.50.50.5-0.90.50.20.50.51.21.10.1-1.21.2-0.3
Rb content in liver2.53.24.31.0-1.62.02.0-1.91.4-1.9-1.9-1.9-1.91.92.02.0-2.0-2.01.9-2.1-2.0-2.1-2.1-1.7-1.8-1.70.3-0.31.3
Se content in liver0.91.23.21.3-1.51.20.9-0.71.5-0.5-1.1-1.1-1.10.11.01.0-1.0-1.00.7-0.6-1.0-1.0-1.00.70.1-1.5-1.81.80.3
Sr content in liver0.40.31.5-1.20.9-0.4-0.30.3-1.00.30.40.40.40.1-0.4-0.40.40.4-0.20.10.30.40.4-0.70.10.41.2-1.20.4
Zn content in liver1.71.92.7-1.61.6-1.5-1.61.3-1.51.31.61.61.6-1.1-1.6-1.61.61.6-1.51.41.11.41.40.61.21.40.5-0.5-0.6
Bone: minimum diameter2.64.98.2-0.21.3-2.3-2.72.1-0.81.92.72.82.8-2.3-2.3-2.32.32.3-2.72.32.02.32.32.71.92.3-1.41.4-2.9
Time in familiar zone, hab. session 10.10.10.30.0-0.00.30.4-0.3-0.1-0.2-0.1-0.2-0.20.30.30.3-0.3-0.30.5-0.1-0.1-0.2-0.2-0.5-0.1-0.40.4-0.40.4
Time in novel zone, hab. session 10.30.30.7-0.50.4-0.5-0.60.6-0.30.70.40.50.5-0.8-0.4-0.40.40.4-0.80.20.20.30.30.70.80.3-0.60.6-0.2
Total zone transitions, hab. session 11.82.55.00.3-1.51.81.8-1.81.4-1.8-1.6-1.7-1.71.81.81.8-1.8-1.81.4-1.8-2.2-1.8-1.8-1.4-1.6-1.40.2-0.21.3
Total locomotion distance, hab. session 11.62.23.40.3-1.31.71.9-1.71.1-1.7-1.6-1.7-1.71.71.51.5-1.5-1.51.7-1.4-1.8-1.5-1.5-1.5-1.5-1.50.6-0.61.3
Locomotion velocity, hab. session 12.02.94.30.3-1.41.92.1-2.01.2-2.0-1.9-2.0-2.02.11.71.7-1.7-1.72.0-1.6-2.0-1.7-1.7-1.8-1.8-1.60.8-0.81.6
Time in familiar zone, hab. session 20.00.00.30.1-0.10.10.2-0.30.1-0.3-0.1-0.0-0.00.40.00.0-0.0-0.00.3-0.5-0.10.10.1-0.2-0.40.00.4-0.4-0.2
Time in novel zone, hab. session 20.30.30.9-0.30.4-0.7-0.80.7-0.30.70.80.80.8-0.8-0.5-0.50.50.5-0.90.60.40.40.40.60.70.6-0.50.5-0.5
Total zone transitions, hab. session 25.06.49.71.4-2.52.82.8-3.12.3-3.1-2.4-2.5-2.53.02.82.8-2.8-2.82.5-2.9-3.1-2.7-2.7-2.2-3.0-2.00.5-0.51.3
Total locomotion distance, hab. session 24.86.410.01.0-2.22.83.0-3.01.8-3.0-2.7-2.8-2.83.22.62.6-2.6-2.62.9-2.8-2.8-2.5-2.5-2.6-2.9-2.11.2-1.21.8
Locomotion velocity, hab. session 25.06.710.10.9-2.22.93.1-3.01.8-3.0-2.9-2.9-2.93.22.72.7-2.7-2.72.9-2.8-2.9-2.5-2.5-2.7-2.9-2.31.2-1.22.0
Novel to familiar place preference ratio1.51.63.21.0-1.41.31.2-1.71.5-1.8-0.9-0.8-0.81.61.41.4-1.4-1.41.1-1.7-1.7-1.4-1.4-0.9-1.8-0.6-0.00.0-0.3
Novelty place preference1.21.22.41.0-1.31.11.0-1.41.4-1.5-0.8-0.7-0.71.41.21.2-1.2-1.20.9-1.4-1.4-1.2-1.2-0.7-1.5-0.5-0.10.1-0.4
Time in novel zone, NPP test1.41.52.81.0-1.41.21.1-1.61.4-1.7-0.9-0.8-0.81.51.31.3-1.3-1.31.0-1.6-1.6-1.4-1.4-0.9-1.7-0.6-0.10.1-0.3
Total zone transitions, NPP test3.75.37.51.1-2.22.72.7-2.71.9-2.7-2.6-2.7-2.72.72.32.3-2.3-2.32.6-2.5-2.7-2.3-2.3-2.0-2.4-2.30.6-0.61.8
Total locomotion distance, NPP test6.69.013.90.9-2.43.33.6-3.51.9-3.5-3.4-3.5-3.53.72.92.9-2.9-2.93.6-3.0-3.1-2.9-2.9-3.3-3.3-2.71.8-1.82.6
Locomotion velocity, NPP test5.57.812.10.9-2.33.13.3-3.31.8-3.3-3.2-3.3-3.33.52.72.7-2.7-2.73.4-2.8-2.9-2.7-2.7-3.0-3.1-2.51.6-1.62.4
Intraocular pressure0.60.84.22.0-1.60.70.7-1.01.6-1.1-0.7-0.7-0.70.80.40.4-0.4-0.40.8-0.7-0.3-0.4-0.40.5-1.3-0.2-0.90.9-1.4
Delta distance traveled before/after self-admin2.12.34.61.6-1.71.51.5-2.01.8-2.1-1.5-1.5-1.52.01.41.4-1.4-1.41.4-1.7-1.8-1.5-1.5-1.0-2.1-0.8-0.00.00.2
Delta ambulatory time before/after self-admin2.42.65.11.8-2.11.61.6-2.12.2-2.3-1.6-1.6-1.62.01.41.4-1.4-1.41.3-2.0-2.0-1.5-1.5-0.7-2.2-0.8-0.50.5-0.0
Parametrial fat weight0.10.10.6-0.50.3-0.10.00.1-0.50.0-0.00.00.00.2-0.4-0.40.40.40.30.30.30.70.7-0.2-0.10.10.8-0.80.1
Pavlov. Cond. lever latency0.60.83.61.9-1.20.60.5-0.81.5-0.9-0.2-0.1-0.10.50.80.8-0.8-0.80.4-1.2-0.5-0.7-0.70.4-0.9-0.2-1.21.2-1.3
Pavlov. Cond. magazine entry latency1.82.34.1-0.91.2-1.5-1.71.8-1.01.81.31.31.3-2.0-1.7-1.71.71.7-1.72.01.41.61.61.82.01.0-0.90.9-0.7
Pavlov. Cond. change in total contacts0.40.41.8-1.20.40.00.1-0.4-0.5-0.5-0.1-0.1-0.10.80.10.1-0.1-0.10.0-0.2-0.6-0.3-0.3-1.2-0.80.41.3-1.30.6
Pavlov. Cond. index score1.21.53.1-1.51.3-1.2-1.31.4-1.31.40.90.70.7-1.3-1.5-1.51.51.5-1.21.81.11.41.40.81.40.80.1-0.10.1
Pavlov. Cond. latency score1.51.94.1-1.71.6-1.4-1.41.6-1.61.71.00.80.8-1.5-1.7-1.71.71.7-1.32.01.31.61.60.81.70.90.3-0.30.3
Pavlov. Cond. lever contacts0.40.42.4-1.50.8-0.3-0.20.3-1.10.3-0.1-0.3-0.30.0-0.5-0.50.50.5-0.10.70.10.30.3-0.70.30.11.2-1.21.2
Pavlov. Cond. magazine entry number2.73.44.91.5-1.72.02.1-2.11.5-2.1-1.8-1.7-1.72.12.12.1-2.1-2.12.1-2.2-1.7-2.0-2.0-1.7-2.0-1.60.4-0.40.9
Pavlov. Cond. intertrial magazine entries2.02.43.81.3-1.71.71.8-1.71.6-1.7-1.4-1.5-1.51.51.91.9-1.9-1.91.5-1.8-1.7-1.9-1.9-1.0-1.5-1.4-0.30.30.6
Pavlov. Cond. lever-magazine prob. diff.0.81.02.2-1.41.1-1.0-1.11.1-1.11.20.70.60.6-1.1-1.2-1.21.21.2-1.01.50.81.11.10.61.20.70.1-0.10.2
Pavlov. Cond. response bias1.31.52.8-1.51.4-1.3-1.41.4-1.31.41.11.01.0-1.3-1.5-1.51.51.5-1.41.71.01.31.30.81.31.10.2-0.2-0.2
Pavlov. Cond. lever latency1.21.75.4-2.32.1-1.2-1.11.4-2.21.40.90.90.9-1.0-1.1-1.11.11.1-0.91.01.11.21.2-0.31.50.81.3-1.31.0
Pavlov. Cond. magazine entry latency0.20.21.50.7-0.50.20.3-0.60.6-0.8-0.1-0.1-0.10.80.10.1-0.1-0.10.4-0.5-0.2-0.2-0.2-0.4-1.20.40.5-0.5-0.8
Pavlov. Cond. change in total contacts0.71.02.71.6-1.40.90.9-1.21.5-1.3-0.7-0.7-0.71.11.01.0-1.0-1.00.8-1.0-0.8-1.0-1.0-0.3-1.6-0.3-0.30.3-0.8
Pavlov. Cond. index score0.60.82.81.7-1.50.80.8-1.11.5-1.2-0.6-0.6-0.60.90.70.7-0.7-0.70.8-0.7-0.7-0.8-0.80.0-1.3-0.3-0.60.6-0.9
Pavlov. Cond. latency score0.50.62.71.7-1.30.60.5-0.81.4-0.9-0.4-0.4-0.40.60.50.5-0.5-0.50.5-0.5-0.4-0.6-0.60.3-1.1-0.2-0.70.7-1.1
Pavlov. Cond. lever contacts1.52.05.92.4-2.21.51.3-1.52.4-1.4-1.1-1.1-1.10.91.31.3-1.3-1.31.1-1.0-1.3-1.4-1.40.4-1.2-1.2-1.61.6-0.7
Pavlov. Cond. magazine entry number0.50.62.1-1.11.0-0.7-0.81.0-1.01.20.60.60.6-1.1-0.6-0.60.60.6-0.90.80.60.60.60.61.40.2-0.30.30.5
Pavlov. Cond. intertrial magazine entries1.21.58.22.1-1.71.00.6-0.52.0-0.3-0.8-0.8-0.8-0.40.60.6-0.6-0.60.5-0.1-0.7-0.4-0.41.70.4-1.5-2.92.9-0.6
Pavlov. Cond. lever-magazine prob. diff.0.81.03.31.8-1.60.90.8-1.11.7-1.2-0.7-0.7-0.70.90.80.8-0.8-0.80.8-0.8-0.8-0.9-0.90.0-1.4-0.4-0.60.6-0.9
Pavlov. Cond. response bias0.81.12.71.7-1.61.11.1-1.31.6-1.3-0.9-0.9-0.91.00.90.9-0.9-0.91.0-0.9-1.0-1.0-1.0-0.2-1.3-0.7-0.60.6-0.5
Time in closed arm before self-admin0.40.53.0-1.10.7-0.00.2-0.0-1.0-0.1-0.1-0.1-0.10.40.10.1-0.1-0.10.20.10.1-0.2-0.2-1.4-0.10.11.7-1.71.0
Time in closed arm after self-admin2.42.43.9-0.41.4-1.7-1.81.6-1.11.51.81.81.8-1.5-1.8-1.81.81.8-1.61.92.01.71.71.21.21.7-0.10.1-1.5
Time in open arm before self-admin0.40.40.9-0.90.7-0.8-0.80.7-0.60.70.80.70.7-0.6-0.7-0.70.70.7-0.90.60.10.80.80.50.60.70.0-0.0-0.5
Time in open arm after self-admin0.60.61.10.7-0.90.90.8-0.90.8-0.8-0.9-0.9-0.90.70.90.9-0.9-0.90.7-1.0-1.0-0.9-0.9-0.3-0.5-0.8-0.30.30.5
Bone: periosteal estimation2.85.711.60.11.4-2.7-2.72.2-0.81.92.82.82.8-2.2-2.7-2.72.72.7-2.72.52.62.72.72.71.62.9-1.11.1-3.4
Bone: periosteal perimeter5.69.212.2-1.72.8-3.5-3.43.3-2.43.13.43.43.4-3.1-3.4-3.43.43.4-3.53.33.33.43.42.52.83.3-0.30.3-2.5
Bone: post-yield work0.30.41.60.9-0.80.30.3-0.81.0-1.0-0.1-0.1-0.10.80.30.3-0.3-0.30.1-0.9-0.8-0.6-0.6-0.1-1.30.3-0.30.3-0.9
Progressive ratio test 1 active lever presses0.10.10.60.7-0.60.20.1-0.30.7-0.40.0-0.0-0.00.20.10.1-0.1-0.10.0-0.4-0.3-0.0-0.00.5-0.40.0-0.70.7-0.8
Progressive ratio test 1 breakpoint0.10.10.70.5-0.4-0.0-0.0-0.20.5-0.30.20.10.10.2-0.1-0.10.10.1-0.1-0.3-0.20.10.10.4-0.40.3-0.40.4-0.9
Progressive ratio test 1 inactive lever presses0.20.20.4-0.20.4-0.4-0.60.5-0.30.60.50.50.5-0.6-0.4-0.40.40.4-0.50.40.50.40.40.50.70.2-0.30.3-0.2
Progressive ratio test 2 active lever presses0.10.10.60.4-0.30.10.1-0.40.4-0.50.0-0.0-0.00.50.00.0-0.0-0.00.2-0.3-0.10.00.0-0.2-0.80.30.2-0.2-0.6
Progressive ratio test 2 breakpoint0.10.10.60.3-0.30.20.2-0.50.3-0.6-0.1-0.1-0.10.60.10.1-0.1-0.10.2-0.4-0.2-0.1-0.1-0.3-0.80.20.3-0.3-0.4
Progressive ratio test 2 inactive lever presses0.00.00.1-0.20.3-0.2-0.20.1-0.30.10.20.20.20.0-0.1-0.10.10.1-0.1-0.00.20.20.2-0.20.00.20.4-0.40.1
Incentive Sensitization - Responses0.80.81.5-1.01.2-1.0-0.90.8-1.20.70.80.80.8-0.4-0.9-0.90.90.9-0.70.91.10.90.9-0.30.41.11.1-1.1-0.2
Incentive Sensitization - Breakpoint1.01.01.8-1.11.3-1.1-1.01.0-1.30.90.90.90.9-0.6-1.1-1.11.11.1-0.91.01.21.11.1-0.10.61.21.1-1.1-0.2
Sum of active levers in priming session hrs 5-60.50.51.90.40.1-0.8-0.90.40.20.20.80.70.7-0.4-0.8-0.80.80.8-0.90.60.40.60.60.90.01.1-0.50.5-1.4
Progressive ratio0.20.31.30.20.1-0.4-0.30.0-0.1-0.20.60.50.50.2-0.5-0.50.50.5-0.20.50.50.70.70.0-0.70.90.4-0.4-1.1
Food seeking constrained by brief footshock0.70.91.9-0.91.1-1.0-0.91.0-1.10.91.01.01.0-0.7-0.9-0.90.90.9-0.71.41.11.11.10.20.31.00.7-0.7-0.7
Seeking ratio, punishment vs. effort0.10.20.8-0.40.4-0.2-0.40.6-0.40.70.10.20.2-0.7-0.1-0.10.10.1-0.30.40.20.00.00.40.9-0.3-0.40.40.4
Retroperitoneal fat weight0.31.12.90.10.8-1.1-0.91.2-0.81.10.70.70.7-1.0-1.3-1.31.31.3-0.51.31.71.51.51.00.71.00.1-0.1-0.9
Reaction time number correct3.65.28.22.7-2.92.52.6-2.42.7-2.3-2.8-2.8-2.81.92.52.5-2.5-2.52.3-2.5-2.0-2.3-2.3-0.6-2.0-2.2-1.01.00.9
Reaction time mean minus median0.71.03.1-1.81.6-0.9-0.81.0-1.71.00.80.90.9-0.6-1.0-1.01.01.0-0.60.90.70.80.8-0.30.90.61.2-1.20.6
Reaction time mean minus median AUC0.81.02.4-1.51.4-0.9-1.01.2-1.41.30.80.90.9-1.1-1.0-1.01.01.0-0.91.00.71.01.00.51.40.40.3-0.30.4
Reaction time num false alarms0.10.21.41.2-0.60.40.4-0.40.5-0.5-0.3-0.3-0.30.40.30.3-0.3-0.30.80.10.2-0.1-0.1-0.0-0.6-0.4-0.20.2-0.4
Reaction time num false alarms AUC0.30.42.41.5-0.90.70.7-0.70.9-0.8-0.4-0.4-0.40.60.50.5-0.5-0.50.9-0.2-0.1-0.3-0.3-0.0-0.9-0.5-0.30.3-0.6
Reaction time trials correct on left3.65.28.22.7-2.92.52.6-2.42.7-2.3-2.8-2.8-2.81.92.52.5-2.5-2.52.3-2.5-2.0-2.3-2.3-0.6-2.0-2.2-1.01.00.9
Reaction time trials on left3.65.18.22.7-2.92.52.5-2.42.7-2.3-2.8-2.7-2.71.92.42.4-2.4-2.42.3-2.5-2.0-2.2-2.2-0.6-1.9-2.2-1.01.00.9
Reaction time mean0.10.10.6-0.70.6-0.4-0.40.3-0.50.30.60.60.6-0.1-0.2-0.20.20.2-0.30.30.00.10.1-0.30.20.40.5-0.5-0.0
Reaction time mean AUC0.10.10.5-0.70.5-0.2-0.20.1-0.50.00.40.40.40.1-0.0-0.00.00.0-0.10.1-0.10.00.0-0.6-0.00.30.7-0.70.1
Median of all reaction times0.10.10.3-0.40.3-0.3-0.30.1-0.20.10.50.50.5-0.10.10.1-0.1-0.1-0.30.2-0.1-0.1-0.1-0.30.10.40.2-0.2-0.1
Reaction time omissions0.50.71.2-0.30.8-0.7-0.80.9-0.81.00.70.70.7-0.9-1.1-1.11.11.1-0.51.01.01.11.10.81.10.4-0.10.1-0.2
Reaction time false alarm rate0.30.51.2-0.00.6-0.6-0.70.6-0.50.51.01.01.0-0.4-0.7-0.70.70.7-0.41.10.90.80.80.30.30.60.2-0.2-0.9
Reaction time premature initiation rate2.02.75.2-0.4-1.11.51.7-1.90.8-2.1-1.4-1.5-1.52.31.61.6-1.6-1.61.4-2.0-2.3-1.8-1.8-2.3-2.2-0.71.4-1.41.0
Reaction time premature initiations4.56.49.81.3-2.62.62.8-3.02.3-3.1-2.6-2.6-2.63.12.72.7-2.7-2.72.4-3.1-3.0-2.7-2.7-2.2-3.1-1.70.6-0.61.1
Std. dev. reaction times0.20.31.6-1.30.9-0.4-0.30.4-1.00.40.40.40.4-0.1-0.4-0.40.40.4-0.20.30.10.30.3-0.60.30.31.0-1.00.5
Reaction time trials completed3.65.18.22.7-2.92.52.5-2.42.7-2.3-2.8-2.7-2.71.92.42.4-2.4-2.42.3-2.5-2.0-2.2-2.2-0.6-1.9-2.2-1.01.00.9
Reaction time trials AUC4.26.09.32.8-3.02.72.8-2.62.8-2.5-3.0-3.0-3.02.12.62.6-2.6-2.62.5-2.7-2.2-2.5-2.5-0.8-2.1-2.4-1.01.01.0
Run reversals in cocaine runway, females0.10.10.70.00.2-0.20.00.3-0.40.3-0.1-0.0-0.0-0.2-0.2-0.20.20.20.20.80.70.50.50.10.10.10.3-0.30.0
Run reversals in cocaine runway, males0.60.63.2-1.01.0-0.5-0.30.2-1.00.00.30.30.30.4-0.4-0.40.40.4-0.00.50.50.90.9-0.9-0.50.91.8-1.80.2
Latency to leave start box in cocaine runway0.20.20.8-0.2-0.10.20.3-0.60.1-0.70.0-0.1-0.10.80.20.2-0.2-0.20.3-0.6-0.5-0.2-0.2-0.8-0.90.20.7-0.7-0.2
Latency to leave start box in cocaine runway, F0.40.40.90.1-0.50.70.7-0.80.5-0.8-0.5-0.6-0.60.90.70.7-0.7-0.70.7-1.0-1.0-0.6-0.6-0.7-0.8-0.60.2-0.20.2
Latency to leave start box in cocaine runway, M0.50.41.40.0-0.30.40.6-0.90.2-1.0-0.3-0.4-0.41.20.40.4-0.4-0.40.6-0.7-0.6-0.5-0.5-1.1-1.20.20.9-0.90.0
Std. dev. time between licks in bursts1.82.23.91.6-2.01.71.6-1.61.9-1.5-1.7-1.7-1.71.11.51.5-1.5-1.51.6-1.5-1.6-1.5-1.5-0.3-1.0-1.7-0.80.80.4
Total sessions with >9 infusions1.41.63.1-1.41.4-1.5-1.41.1-1.20.91.51.41.4-0.7-1.5-1.51.51.5-1.30.91.01.51.50.30.41.80.9-0.9-1.1
Short access day 1 total inactive lever presses0.50.61.1-0.80.7-0.9-0.90.7-0.60.61.01.01.0-0.5-0.8-0.80.80.8-1.00.30.40.90.90.40.41.00.2-0.2-0.8
Short access day 10 total inactive lever presses0.70.71.9-0.61.0-0.8-1.01.1-0.91.21.01.01.0-1.2-0.7-0.70.70.7-1.00.81.00.70.70.71.40.4-0.30.30.0
Short access day 1 total infusions1.51.62.8-1.41.3-1.5-1.41.2-1.21.11.41.31.3-0.9-1.6-1.61.61.6-1.50.91.01.61.60.60.71.70.6-0.6-1.0
Short access day 10 total infusions1.82.13.9-0.71.0-1.7-1.61.3-0.71.11.71.61.6-1.1-1.8-1.81.81.8-1.61.31.21.81.81.30.61.9-0.10.1-2.0
Short access total infusions0.60.71.6-1.20.9-1.0-0.80.6-0.90.40.90.80.8-0.2-0.9-0.90.90.9-0.80.40.41.01.0-0.10.01.31.0-1.0-0.7
Short access day 1 locomotion0.50.51.0-1.00.9-0.8-0.70.7-0.90.60.70.70.7-0.4-0.8-0.80.80.8-0.80.50.60.90.9-0.10.40.90.8-0.8-0.2
Short access day 10 total locomotion0.60.71.6-1.31.1-0.9-0.80.7-1.10.60.90.80.8-0.3-0.9-0.90.90.9-0.80.60.60.80.8-0.20.31.01.0-1.0-0.2
Short access total locomotion1.91.96.2-2.52.0-1.5-1.21.1-2.00.91.31.21.2-0.4-1.3-1.31.31.3-1.10.80.91.31.3-0.80.41.72.1-2.1-0.0
One hour access (0.3 mA shock)0.10.10.70.8-0.50.20.2-0.40.6-0.6-0.2-0.2-0.20.50.10.1-0.1-0.10.2-0.3-0.0-0.1-0.10.0-0.70.2-0.10.1-0.6
Compulsive drug intake0.60.62.2-0.3-0.10.50.7-0.7-0.2-0.8-0.6-0.6-0.61.10.60.6-0.6-0.60.8-0.5-0.5-0.6-0.6-1.5-1.0-0.21.4-1.40.8
One hour access (shock baseline)0.20.21.21.1-0.5-0.0-0.10.10.60.10.10.10.1-0.4-0.1-0.10.10.1-0.10.10.30.10.10.90.1-0.0-1.11.1-0.7
Social response proportion0.50.51.5-0.0-0.20.60.8-0.70.0-0.7-0.9-0.9-0.91.00.50.5-0.5-0.51.0-0.3-0.4-0.6-0.6-1.2-0.9-0.31.1-1.10.9
Social responses0.40.52.3-0.6-0.00.60.7-0.4-0.2-0.3-1.0-1.0-1.00.50.60.6-0.6-0.60.7-0.3-0.6-0.7-0.7-1.0-0.1-0.70.7-0.71.5
Social time0.70.92.8-0.6-0.20.81.1-0.9-0.1-0.9-0.9-0.8-0.81.20.80.8-0.8-0.81.1-0.7-0.8-0.6-0.6-1.7-1.0-0.61.6-1.61.2
Soleus weight0.92.87.8-1.1-0.21.31.8-1.3-0.3-1.3-1.8-1.9-1.91.81.41.4-1.4-1.41.8-1.3-1.3-1.4-1.4-2.8-1.3-1.12.4-2.42.8
Bone: stiffness1.82.84.8-2.22.2-2.0-2.01.7-2.11.61.81.81.8-1.2-1.8-1.81.81.8-1.91.51.51.51.50.31.12.01.0-1.0-0.5
Tibialis anterior weight0.20.62.3-0.8-0.00.50.7-0.6-0.2-0.7-0.7-0.7-0.71.00.50.5-0.5-0.50.6-0.6-0.8-0.6-0.6-1.5-0.7-0.11.5-1.51.2
Time to tail flick, vehicle, before self-admin1.21.34.6-0.9-0.00.91.0-0.8-0.2-0.7-1.1-1.2-1.21.01.21.2-1.2-1.21.1-0.8-1.1-1.2-1.2-1.8-0.3-1.11.3-1.32.1
Time to tail flick, vehicle, after self-admin2.12.24.4-1.92.1-1.6-1.31.3-2.11.21.41.51.5-0.6-1.5-1.51.51.5-1.11.41.71.41.4-0.70.51.82.1-2.1-0.2
Time to tail flick, test, before self-admin0.50.51.10.8-1.00.80.6-0.61.0-0.5-0.6-0.6-0.60.20.80.8-0.8-0.80.7-0.5-0.9-0.7-0.70.20.0-1.1-0.90.90.0
Time to tail flick, test, after self-admin0.60.71.0-0.71.0-1.0-1.00.9-1.00.80.80.70.7-0.7-0.9-0.90.90.9-0.80.80.80.90.90.30.81.00.4-0.4-0.4
Delta time to tail flick, vehicle, before/after SA0.40.41.70.30.3-0.7-0.60.4-0.20.30.80.80.8-0.2-0.8-0.80.80.8-0.50.60.90.80.80.4-0.41.00.2-0.2-1.3
Delta time to tail flick, test, before/after SA1.81.63.4-1.61.8-1.5-1.21.3-1.81.21.01.01.0-0.8-1.4-1.41.41.4-1.21.01.41.41.4-0.10.71.51.2-1.2-0.0
Tibia length9.928.042.0-4.05.8-5.7-5.86.4-5.66.55.15.25.2-6.1-5.8-5.85.85.8-5.16.36.25.75.74.06.14.1-0.30.3-1.7
Ambulatory time before self-admin1.11.23.1-0.81.2-1.0-1.11.5-1.31.61.01.11.1-1.6-0.9-0.90.90.9-0.91.51.40.90.90.81.80.3-0.10.1-0.1
Ambulatory time after self-admin0.40.41.61.2-1.10.50.4-0.81.2-0.8-0.4-0.4-0.40.50.30.3-0.3-0.30.2-0.7-0.7-0.4-0.40.4-0.8-0.2-0.80.8-0.7
Bone: tissue strength0.40.41.9-0.3-0.30.30.3-0.80.4-1.00.10.10.11.00.30.3-0.3-0.30.1-1.0-1.0-0.3-0.3-0.6-1.40.40.6-0.6-0.7
Total heroin consumption3.13.75.2-0.61.5-2.2-2.21.9-1.01.72.32.32.3-1.7-2.3-2.32.32.3-2.21.71.82.22.21.81.32.3-0.60.6-2.2
Bone: trabecular number0.50.82.21.2-1.30.70.6-0.71.4-0.6-0.5-0.5-0.50.21.01.0-1.0-1.00.1-0.8-1.0-1.1-1.10.4-0.3-0.6-1.51.5-0.3
Bone: trabecular spacing0.30.31.30.00.5-0.4-0.40.5-0.60.50.30.10.1-0.4-0.9-0.90.90.90.10.91.10.90.90.30.30.20.3-0.3-0.1
Bone: trabecular thickness0.50.51.60.5-1.00.50.6-0.81.1-0.9-0.3-0.2-0.20.61.01.0-1.0-1.0-0.1-0.9-1.3-1.0-1.0-0.2-0.7-0.0-0.50.5-0.4
Bone: trabecular tissue density0.20.30.9-0.10.50.10.00.3-0.70.4-0.4-0.4-0.4-0.2-0.8-0.80.80.80.71.00.80.60.6-0.10.4-0.60.7-0.70.9
Water consumed over 24 hours0.60.71.80.9-0.81.00.8-0.60.7-0.4-1.2-1.2-1.20.20.80.8-0.8-0.80.8-0.7-0.6-0.8-0.80.00.1-1.3-0.80.81.0
Number of responses in last shaping day2.12.23.4-1.61.8-1.7-1.61.6-1.81.61.61.51.5-1.3-1.6-1.61.61.6-1.51.61.61.61.60.41.31.50.8-0.8-0.4