Add1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	Adipose	intron excision ratio	chr14_80346428_80348939	0.02	0.02	3.1e-03	0.01	0.02	0.01	0.01	2.3e-02	4.3e-03	8.9e-03	1.6e-02
2	Adipose	intron excision ratio	chr14_80348331_80348939	0.04	0.03	3.8e-04	0.02	0.03	0.02	0.02	1.9e-03	2.8e-04	1.4e-03	1.1e-03
3	Adipose	gene expression	Add1	0.43	0.18	0.0e+00	0.24	0.23	0.22	0.23	3.1e-26	4.9e-25	3.2e-24	6.7e-25
4	Adipose	intron excision ratio	chr14_80346428_80348287	0.02	0.02	9.2e-03	0.01	0.01	0	0	6.2e-02	3.3e-02	1.3e-01	1.1e-01
5	Liver	intron excision ratio	chr14_80346428_80348287	0.03	0.02	5.2e-05	0.04	0.04	0.04	0.03	3.8e-05	5.9e-05	8.6e-05	1.4e-04
6	pVTA	intron excision ratio	chr14_80346428_80348939	0.04	0.03	2.8e-03	0.03	0.04	0.03	0.03	1.3e-03	7.7e-04	1.2e-03	1.1e-03
7	Liver	intron excision ratio	chr14_80348331_80348939	0.02	0.02	3.8e-03	0.02	0.02	0.02	0.02	2.2e-03	5.2e-03	4.5e-03	4.7e-03
8	pVTA	isoform ratio	XM_039091611.2	0.09	0.07	2.8e-04	0.03	0.05	0.04	0.04	3.4e-03	8.0e-05	1.7e-04	1.5e-04
9	NAcc	gene expression	Add1	0.01	0.01	6.3e-03	0.01	0.01	0.01	0.01	7.2e-03	8.8e-03	3.7e-02	1.1e-02
10	RMTg	intron excision ratio	chr14_80336416_80337025	0.26	0.17	7.5e-03	0.09	0.02	0.02	0.05	2.1e-03	1.1e-01	9.1e-02	1.9e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6	7	8	9	10
Bone: apparent density	0.7	1.2	1.8	1.3	-1.2	-1.2	-1.3	-1.0	1.3	-1.0	1.2	0.6	0.6
Area under the delay curve	0.6	0.6	1.9	-0.3	-0.2	0.6	0.9	0.7	-1.0	0.5	-1.4	0.9	0.9
BMI with tail	1.5	5.3	11.1	-2.7	2.0	2.1	3.2	1.7	-3.2	1.7	-3.3	-0.0	-0.0
BMI without tail	1.0	3.1	5.9	-2.2	1.8	1.8	2.4	1.2	-2.4	1.0	-2.4	-0.1	-0.1
Body weight	5.3	23.1	31.4	-5.5	4.9	5.2	5.6	4.8	-5.6	4.9	-5.1	-2.8	-2.8
Weight adjusted by age	2.2	3.4	5.0	-2.0	1.7	2.0	2.2	1.8	-2.2	1.9	-2.2	-0.7	-0.7
Bone surface	0.2	0.3	1.1	-0.4	0.3	0.5	0.4	1.0	-0.4	1.0	-0.4	-0.3	-0.3
Bone volume	0.0	0.0	0.0	0.2	-0.2	-0.1	-0.2	0.1	0.2	0.1	0.2	0.0	0.0
Breakpoint value in progressive ratio session	0.1	0.1	0.2	0.2	-0.2	-0.3	-0.2	-0.5	0.2	-0.2	0.1	0.2	0.2
Number of licking bursts	1.5	2.5	3.6	-1.6	1.7	1.6	1.2	1.9	-1.2	1.7	-0.7	-1.9	-1.9
Context. condit. distance diff. score	0.2	0.3	0.7	0.6	-0.7	-0.5	-0.6	-0.3	0.5	-0.8	0.4	0.4	0.4
Locomotion velocity, session 1	1.0	1.1	1.8	1.2	-1.0	-0.7	-1.3	-1.1	1.3	-1.3	1.3	0.2	0.2
Locomotion distance, session 1	0.3	0.4	0.7	0.8	-0.8	-0.5	-0.7	-0.8	0.7	-0.6	0.6	0.4	0.4
Locomotion velocity, session 2	4.2	4.9	8.9	2.6	-2.0	-1.9	-3.0	-1.9	3.0	-2.2	3.0	0.1	0.1
Locomotion distance, session 2	2.4	3.3	5.5	2.3	-2.3	-1.4	-2.0	-1.8	2.0	-1.7	1.5	1.5	1.5
Locomotion velocity, session 3	0.1	0.1	0.5	0.5	-0.7	0.2	-0.3	0.1	0.3	-0.0	0.0	0.4	0.4
Locomotion distance, session 3	0.1	0.1	0.2	0.0	-0.2	0.5	0.2	0.3	-0.2	0.0	-0.4	0.4	0.4
Stereotopy head waving bouts, day 3	1.5	1.7	4.5	1.1	-0.8	-1.7	-1.2	-1.7	1.1	-2.1	1.1	0.8	0.8
Stereotopy head waving duration, day 3	1.4	1.6	3.8	1.0	-0.9	-1.7	-1.0	-1.7	0.9	-1.9	0.8	1.1	1.1
Locomotion velocity, session 7	2.0	2.2	4.4	-1.1	1.2	1.4	0.8	2.1	-0.8	1.7	-0.4	-2.1	-2.1
Locomotion distance, session 7	0.1	0.1	0.4	0.4	-0.6	0.3	-0.3	0.6	0.3	0.3	0.1	-0.3	-0.3
Stereotopy head waving bouts, day 7	0.7	0.7	2.1	-1.0	0.6	0.3	1.3	0.4	-1.3	0.1	-1.5	0.3	0.3
Stereotopy head waving duration, day 7	1.4	1.7	3.6	-1.5	1.2	0.8	1.8	1.1	-1.8	0.8	-1.9	-0.1	-0.1
Locomotion velocity, session 8	1.2	1.4	2.9	1.4	-1.0	-1.2	-1.6	-0.8	1.6	-1.0	1.7	-0.1	-0.1
Locomotion distance, session 8	1.7	2.5	3.8	2.0	-1.8	-1.4	-1.9	-1.3	1.9	-1.8	1.6	0.8	0.8
Degree of sensitization distance	0.8	0.8	2.0	0.9	-0.5	-0.9	-1.2	-0.3	1.3	-0.4	1.4	-0.8	-0.8
Degree of sensitization stereotypy	1.4	1.5	3.1	-1.4	1.1	0.9	1.7	1.0	-1.7	0.9	-1.8	-0.2	-0.2
Conditioned locomotion	0.4	0.5	1.4	-0.2	-0.3	0.5	0.7	0.6	-0.8	0.9	-1.2	0.8	0.8
Cocaine response after cond. corrected	1.9	2.2	3.0	1.5	-1.7	-1.7	-1.2	-1.7	1.2	-1.7	0.7	1.6	1.6
Cocaine response after cond. not corrected	0.8	0.9	1.3	1.0	-1.1	-1.0	-0.8	-1.1	0.7	-1.1	0.4	1.0	1.0
Cocaine response before conditioning	1.2	1.5	2.4	-1.2	1.3	1.3	0.8	1.4	-0.8	1.3	-0.4	-1.5	-1.5
Saline control response	0.2	0.2	0.4	0.5	-0.4	-0.6	-0.6	-0.5	0.6	-0.5	0.6	-0.1	-0.1
Bone: connectivity density	0.4	0.7	1.1	1.0	-1.1	-0.8	-0.9	-0.6	0.9	-0.6	0.7	0.7	0.7
Bone: cortical apparent density	0.4	0.6	1.5	-0.4	0.1	-0.6	0.7	-0.3	-0.7	-0.5	-1.0	1.2	1.2
Bone: cortical area	5.8	8.9	13.2	-3.2	3.0	3.6	3.0	3.6	-3.0	3.1	-2.5	-2.2	-2.2
Bone: cortical porosity	0.3	0.3	0.5	0.7	-0.7	-0.3	-0.6	-0.4	0.6	-0.6	0.5	0.4	0.4
Bone: cortical porosity	0.1	0.1	0.2	0.3	-0.3	0.3	-0.2	-0.0	0.1	-0.5	0.0	0.5	0.5
Bone: cortical thickness	3.5	5.8	9.1	-2.6	2.2	3.0	2.7	3.0	-2.7	2.2	-2.5	-1.3	-1.3
Bone: cortical thickness	0.4	0.5	1.4	-0.1	-0.4	-0.0	0.7	0.1	-0.7	0.3	-1.2	1.1	1.1
Bone: cortical tissue density	0.5	0.7	1.8	-0.3	-0.0	-0.7	0.6	-0.5	-0.7	-0.6	-0.9	1.3	1.3
Condit. Reinf. active minus inactive responses	1.6	1.8	3.0	1.3	-1.4	-1.7	-1.1	-1.6	1.0	-1.5	0.7	1.3	1.3
Condit. Reinf. active-inactive response ratio	3.1	3.3	5.0	2.0	-1.9	-1.8	-1.8	-2.2	1.8	-2.1	1.4	1.5	1.5
Condit. Reinf. active responses	0.7	0.8	2.0	0.8	-0.9	-1.4	-0.7	-1.1	0.6	-1.0	0.4	0.8	0.8
Condit. Reinf. inactive responses	1.2	1.5	2.1	-1.4	1.4	0.6	1.2	1.5	-1.2	1.5	-0.9	-1.2	-1.2
Incentive salience index mean	0.2	0.2	1.0	0.3	-0.4	-1.0	-0.2	-0.6	0.2	-0.4	0.0	0.4	0.4
Condit. Reinf. lever presses	0.6	0.9	1.6	-1.1	0.9	0.0	1.1	0.9	-1.1	1.3	-1.1	-0.6	-0.6
Condit. Reinf. active minus inactive responses	0.6	0.7	1.3	-0.9	1.1	0.7	0.5	1.0	-0.4	0.9	-0.0	-1.2	-1.2
Condit. Reinf. active-inactive response ratio	0.2	0.2	0.6	0.3	-0.4	-0.5	-0.0	-0.2	0.0	-0.2	-0.2	0.8	0.8
Condit. Reinf. active responses	0.1	0.2	0.4	0.0	0.3	-0.0	-0.4	0.5	0.4	0.3	0.7	-0.6	-0.6
Condit. Reinf. inactive responses	0.2	0.2	0.7	0.2	0.1	-0.3	-0.6	0.0	0.6	-0.1	0.9	-0.5	-0.5
Condit. Reinf. lever presses	0.3	0.4	0.7	-0.7	0.7	0.8	0.7	0.8	-0.7	0.6	-0.6	-0.1	-0.1
Condit. Reinf. lever reinforcers received	0.1	0.1	0.4	-0.2	0.3	0.3	0.0	0.7	0.0	0.5	0.2	-0.4	-0.4
Conditioned reinforcement - actives	0.4	0.6	1.4	-0.8	0.4	0.8	1.0	0.8	-1.0	0.8	-1.2	-0.0	-0.0
Conditioned reinforcement - inactives	0.6	0.8	1.0	-1.0	1.0	1.0	1.0	1.0	-0.9	1.0	-0.8	-0.7	-0.7
Conditioned locomotion	1.0	1.3	1.8	-1.2	1.0	1.2	1.3	1.2	-1.3	1.2	-1.3	-0.6	-0.6
Patch foraging indifference point 0 sec	0.0	0.0	0.2	0.1	0.0	-0.2	-0.1	-0.2	0.1	-0.4	0.2	-0.1	-0.1
Patch foraging indifference point AUC	0.3	0.4	0.8	0.5	-0.3	-0.5	-0.8	-0.8	0.8	-0.7	0.9	0.4	0.4
Delay disc. indifference point, 0s delay	1.8	1.9	5.6	-0.3	-0.7	0.7	1.4	1.0	-1.5	0.7	-2.4	1.8	1.8
Delay disc. indifference point, 16s delay	0.2	0.3	0.9	0.4	-0.6	-0.3	-0.1	-0.4	0.1	-0.4	-0.1	1.0	1.0
Delay disc. indifference point, 2s delay	0.6	0.6	1.9	0.3	-0.9	0.1	0.4	0.2	-0.5	0.0	-1.0	1.4	1.4
Delay disc. indifference point, 24s delay	0.7	0.8	2.2	-0.1	-0.5	0.4	0.8	0.4	-0.9	0.3	-1.5	1.3	1.3
Delay disc. indifference point, 4s delay	0.3	0.3	0.9	0.5	-0.8	-0.3	-0.2	-0.2	0.1	-0.3	-0.2	0.9	0.9
Delay disc. indifference point, 8s delay	0.7	0.8	1.2	-1.0	0.8	1.0	1.1	1.1	-1.1	1.0	-1.1	-0.4	-0.4
Indifference point function ln k	0.2	0.3	0.7	0.5	-0.3	-0.7	-0.7	-0.3	0.7	-0.4	0.8	-0.5	-0.5
Indifference point function log k	0.2	0.3	0.7	0.5	-0.3	-0.7	-0.7	-0.3	0.7	-0.4	0.8	-0.5	-0.5
Patch foraging total patch changes 0 sec	0.0	0.0	0.1	-0.0	0.2	-0.1	-0.1	-0.2	0.1	-0.4	0.2	-0.2	-0.2
Patch foraging total patch changes 12 sec	0.2	0.3	0.5	-0.7	0.6	0.5	0.7	0.4	-0.7	0.6	-0.7	0.1	0.1
Patch foraging total patch changes 18 sec	0.0	0.1	0.2	0.0	0.1	-0.4	-0.1	-0.5	0.1	-0.3	0.2	0.3	0.3
Patch foraging total patch changes 24 sec	0.2	0.3	1.1	0.0	-0.3	0.1	0.3	-0.1	-0.3	-0.5	-0.6	1.0	1.0
Patch foraging total patch changes 6 sec	0.1	0.1	0.4	-0.3	0.6	-0.0	-0.1	-0.3	0.2	-0.3	0.5	-0.5	-0.5
Patch foraging time to switch 0 sec	0.9	1.8	4.8	-1.2	0.6	1.4	1.8	1.3	-1.9	1.2	-2.2	0.2	0.2
Patch foraging water rate 0 sec	0.7	1.5	4.4	-0.9	1.6	0.7	0.0	0.9	0.1	0.8	0.9	-2.1	-2.1
Patch foraging water rate 12 sec	0.2	0.4	0.9	0.2	0.2	-0.6	-0.6	-0.7	0.7	-0.9	1.0	-0.5	-0.5
Patch foraging water rate 18 sec	0.2	0.3	0.7	-0.3	0.7	-0.2	-0.1	-0.2	0.2	-0.5	0.5	-0.8	-0.8
Patch foraging water rate 24 sec	0.9	1.2	4.0	-1.0	1.6	0.3	0.1	0.2	-0.0	0.2	0.7	-2.0	-2.0
Patch foraging water rate 6 sec	1.0	1.4	3.4	-1.3	1.8	0.9	0.7	0.8	-0.6	0.6	0.1	-1.8	-1.8
Seeking ratio, delayed vs. immediate footshock	2.2	2.6	5.3	1.6	-1.1	-1.7	-2.1	-1.8	2.1	-1.5	2.3	0.2	0.2
Distance traveled before self-admin	1.1	1.4	2.0	1.4	-1.4	-1.2	-1.2	-1.1	1.1	-1.0	0.8	1.3	1.3
Distance traveled after self-admin	0.3	0.4	1.4	0.4	-0.8	-0.2	0.2	-0.2	-0.2	0.0	-0.7	1.2	1.2
Extensor digitorum longus weight	2.0	7.8	11.8	-3.4	3.4	2.6	3.1	2.4	-3.1	2.5	-2.4	-2.4	-2.4
Bone: elastic displacement	0.8	0.9	1.7	-1.2	1.2	0.8	1.0	1.0	-1.0	1.3	-0.7	-0.6	-0.6
Bone: elastic work	3.2	4.2	6.5	-2.4	2.5	1.7	2.1	2.1	-2.0	2.2	-1.5	-1.9	-1.9
Bone: endosteal estimation	1.5	3.2	5.1	-1.6	1.9	2.0	1.1	2.2	-1.1	2.1	-0.5	-2.2	-2.2
Bone: endosteal perimeter	1.4	3.0	4.6	-1.7	1.9	1.8	1.2	2.0	-1.2	2.2	-0.6	-2.1	-2.1
Epididymis fat weight	1.7	5.9	8.7	-2.8	2.4	2.2	3.0	2.5	-2.9	2.7	-2.8	-1.0	-1.0
Delta time in closed arm before/after self-admin	1.0	0.9	1.4	1.0	-1.1	-0.9	-0.8	-0.9	0.7	-0.8	0.4	1.2	1.2
Delta time in open arm before/after self-admin	1.5	1.5	2.0	-1.3	1.2	1.3	1.4	1.3	-1.4	1.3	-1.3	-0.7	-0.7
Diff in mean of infusions in LGA sessions	1.3	1.6	2.9	1.4	-1.7	-1.1	-0.9	-1.2	0.8	-1.1	0.3	1.7	1.7
Delay discount exponential model param	0.5	0.5	1.5	0.2	0.3	-0.5	-0.8	-0.6	0.8	-0.4	1.2	-0.9	-0.9
Extinction: sum of active levers before priming	0.8	0.9	1.6	-1.0	0.7	0.9	1.2	1.0	-1.2	1.1	-1.2	-0.4	-0.4
Active lever presses in extinction session 6	0.4	0.4	1.1	0.1	-0.5	0.1	0.5	-0.0	-0.5	-0.0	-0.9	1.1	1.1
Bone: final force	5.3	8.4	14.7	-3.0	2.9	3.5	2.8	3.8	-2.7	3.1	-2.2	-2.3	-2.3
Bone: final moment	4.4	7.1	12.1	-2.7	2.7	3.3	2.4	3.5	-2.4	2.6	-1.8	-2.4	-2.4
Food consumed during 24 hour testing period	0.3	0.5	1.4	-0.1	0.5	-0.1	-0.5	0.1	0.6	-0.1	1.0	-1.2	-1.2
Glucose	0.8	1.3	4.6	-0.3	0.8	0.2	-0.3	1.0	0.4	0.7	0.9	-2.2	-2.2
Heart weight	1.4	2.2	2.9	-1.5	1.5	1.7	1.2	1.6	-1.2	1.5	-0.9	-1.7	-1.7
Delay discount hyperbolic model param	0.5	0.5	1.5	0.2	0.3	-0.4	-0.7	-0.6	0.8	-0.4	1.2	-0.9	-0.9
Intermittent access intake day 1-15 change	2.4	5.0	6.3	2.5	-2.4	-2.3	-2.3	-2.3	2.3	-2.3	1.9	1.9	1.9
Intermittent access intake escalation	1.6	3.3	4.2	2.1	-2.0	-1.9	-1.9	-1.9	1.9	-1.9	1.5	1.6	1.6
Intermittent access intake escalation 2	2.5	2.9	3.9	1.9	-1.6	-1.8	-2.0	-1.8	2.0	-1.8	1.9	1.0	1.0
Intermitt. access day 1 inactive lever presses	0.1	0.5	0.8	0.7	-0.6	-0.8	-0.9	-0.8	0.9	-0.8	0.9	0.4	0.4
Intermitt. access day 15 inactive lever presses	0.3	0.7	1.0	0.9	-0.7	-0.9	-1.0	-0.9	1.0	-0.9	1.0	0.4	0.4
Intermitt. access escalation Index	0.6	0.9	1.2	1.1	-1.0	-1.0	-1.1	-1.0	1.1	-1.0	1.0	0.7	0.7
Intermittent access day 1 total infusions	0.8	1.2	3.0	-1.0	0.5	1.1	1.4	1.1	-1.5	1.1	-1.7	0.1	0.1
Intermittent access day 15 total infusions	0.0	0.1	0.2	0.1	-0.3	-0.0	0.1	-0.0	-0.1	-0.0	-0.3	0.4	0.4
Intermittent access terminal intake (last 3 days)	0.1	0.1	0.1	0.3	-0.4	-0.3	-0.3	-0.3	0.2	-0.3	0.1	0.3	0.3
Intermittent access total infusions	0.1	0.1	0.2	-0.4	0.2	0.4	0.5	0.4	-0.5	0.4	-0.5	-0.1	-0.1
Intermittent access day 1 locomotion	0.6	0.8	1.4	-0.9	0.6	0.9	1.1	0.9	-1.1	0.9	-1.2	-0.2	-0.2
Intermittent access day 15 total locomotion	0.3	0.5	1.5	-0.4	0.0	0.6	0.9	0.6	-0.9	0.6	-1.2	0.4	0.4
Intermittent access total locomotion	0.0	0.1	0.2	-0.0	-0.1	0.1	0.3	0.1	-0.3	0.1	-0.4	0.3	0.3
Intermittent access standard deviation	0.3	0.7	0.8	0.9	-0.8	-0.8	-0.9	-0.8	0.9	-0.8	0.8	0.6	0.6
Left kidney weight	3.9	18.1	25.2	-4.9	4.7	5.0	4.6	4.1	-4.6	3.8	-3.9	-3.3	-3.3
Right kidney weight	3.0	13.6	20.1	-4.2	3.7	4.5	4.3	3.6	-4.3	3.3	-3.9	-2.1	-2.1
Cocaine induced anxiety	0.5	0.7	1.1	0.9	-0.6	-0.8	-1.0	-0.8	1.0	-0.8	1.1	0.2	0.2
Post-drug Anxiety	0.3	0.4	1.0	0.6	-0.8	-0.4	-0.2	-0.4	0.2	-0.4	-0.1	1.0	1.0
Baseline Anxiety	1.9	2.2	5.8	-1.3	0.6	1.4	2.0	1.4	-2.0	1.4	-2.4	0.5	0.5
Tail length	1.0	4.0	5.9	-2.1	2.4	2.3	1.6	1.9	-1.5	1.9	-0.8	-2.4	-2.4
Length with tail	3.8	16.6	22.1	-4.5	4.7	4.3	3.8	4.1	-3.7	4.3	-2.7	-4.2	-4.2
Length without tail	3.2	10.4	12.8	-3.6	3.5	3.3	3.2	3.3	-3.2	3.6	-2.5	-3.0	-3.0
Times rat made contact with spout	1.0	1.2	2.6	1.1	-0.7	-1.1	-1.4	-0.9	1.4	-1.1	1.6	-0.2	-0.2
Lifetime Intake	0.1	0.2	0.2	-0.4	0.4	0.4	0.5	0.4	-0.5	0.4	-0.4	-0.3	-0.3
Liver weight, left	0.5	0.8	1.1	-1.0	0.9	0.8	1.0	1.0	-1.0	1.0	-0.8	-0.8	-0.8
Liver weight, right	2.1	3.7	6.1	-2.5	2.3	1.3	2.4	1.5	-2.4	1.8	-2.0	-1.2	-1.2
Locomotor activity	0.8	1.2	3.9	-0.5	1.1	0.5	-0.3	0.7	0.4	0.7	1.1	-2.0	-2.0
Locomotor testing distance	0.6	1.1	1.7	-1.2	1.3	0.9	0.9	1.0	-0.8	1.1	-0.5	-1.3	-1.3
Locomotor testing rearing	1.2	2.5	4.2	-1.7	2.0	1.3	1.2	1.5	-1.1	1.5	-0.5	-2.1	-2.1
Locomotion in novel chamber	0.5	0.7	1.0	0.9	-1.0	-0.8	-0.8	-0.7	0.7	-0.9	0.5	0.9	0.9
Locomotion in novel chamber post-restriction	0.1	0.2	0.6	0.4	-0.7	-0.1	-0.0	-0.1	0.0	-0.1	-0.3	0.8	0.8
Fecal boli incidents, locomotor time 1	0.3	0.5	0.9	0.7	-0.4	-0.9	-0.9	-0.8	0.9	-0.7	1.0	0.1	0.1
Change in fecal boli incidents, locomotor task	0.4	0.4	1.0	0.6	-0.4	-0.6	-0.8	-0.4	0.9	-0.7	1.0	0.1	0.1
Time >=10cm from walls, locomotor time 1	1.8	1.9	4.7	-1.2	0.6	1.3	1.8	1.3	-1.9	1.3	-2.2	0.6	0.6
Bouts of movement, locomotor time 1	0.2	0.2	0.7	-0.3	0.1	0.3	0.6	0.2	-0.6	0.2	-0.8	0.5	0.5
Total resting periods, locomotor time 1	0.2	0.2	0.7	-0.3	0.1	0.4	0.6	0.3	-0.6	0.2	-0.8	0.6	0.6
Rest time, locomotor task time 1	1.7	2.1	3.7	-1.7	1.9	1.4	1.3	1.5	-1.2	1.5	-0.7	-1.6	-1.6
Distance moved, locomotor task time 1	0.1	0.2	0.6	0.5	-0.5	-0.1	-0.3	-0.4	0.3	-0.8	0.1	0.4	0.4
Vertical activity count, locomotor time 1	0.6	1.4	1.9	1.4	-1.4	-1.2	-1.2	-1.2	1.2	-1.2	1.0	0.9	0.9
Time >=10cm from walls, locomotor time 2	0.6	0.8	1.3	-0.9	0.7	1.0	1.1	0.9	-1.1	1.1	-1.1	-0.0	-0.0
Bouts of movement, locomotor time 2	0.1	0.2	0.8	0.2	-0.5	-0.1	0.1	-0.3	-0.1	-0.2	-0.4	0.9	0.9
Total resting periods, locomotor time 2	0.1	0.2	0.5	-0.1	-0.2	0.2	0.4	0.0	-0.5	0.2	-0.7	0.7	0.7
Rest time, locomotor task time 2	1.2	1.5	2.4	-1.4	1.6	1.2	1.1	1.2	-1.0	1.3	-0.6	-1.3	-1.3
Distance moved, locomotor task time 2	0.6	0.7	1.1	0.9	-1.1	-0.6	-0.7	-0.8	0.7	-1.0	0.4	1.0	1.0
Vertical activity count, locomotor time 2	1.4	1.9	3.0	1.6	-1.7	-1.3	-1.4	-1.3	1.3	-1.3	0.9	1.4	1.4
Light reinforcement 1	1.5	3.7	5.3	-2.3	2.2	2.1	2.2	1.9	-2.2	1.7	-1.9	-1.2	-1.2
Light reinforcement 2	2.4	3.7	5.1	-2.2	2.3	2.0	2.0	1.9	-1.9	1.7	-1.5	-1.8	-1.8
Bone: marrow area	1.3	2.9	4.3	-1.5	1.7	2.0	1.1	2.1	-1.0	2.0	-0.5	-2.1	-2.1
Bone: maximum diameter	3.5	6.5	8.8	-2.9	3.0	2.9	2.5	2.7	-2.5	2.3	-1.9	-2.3	-2.3
Bone: maximum force	3.7	6.6	10.3	-2.7	2.7	2.9	2.4	3.2	-2.3	2.7	-1.8	-2.2	-2.2
Bone: maximum moment	3.1	5.4	8.1	-2.4	2.5	2.7	2.0	2.8	-2.0	2.2	-1.4	-2.4	-2.4
Mean time between licks in bursts	0.8	1.9	4.7	1.2	-0.6	-1.3	-1.8	-1.2	1.8	-1.2	2.2	-0.8	-0.8
Mean num. licks in bursts	2.8	4.4	5.9	2.3	-2.2	-2.2	-2.2	-2.4	2.1	-2.3	1.8	1.7	1.7
Cd content in liver	0.1	0.1	0.3	0.1	-0.0	-0.2	-0.3	-0.1	0.3	0.1	0.5	-0.6	-0.6
Co content in liver	0.6	0.7	2.1	-0.5	0.4	1.2	0.5	1.4	-0.5	1.0	-0.5	-0.7	-0.7
Cu content in liver	0.9	1.0	1.6	1.2	-1.3	-1.0	-1.1	-0.5	1.1	-0.9	0.8	1.1	1.1
Fe content in liver	3.4	4.1	7.1	2.5	-2.7	-1.3	-2.1	-1.5	2.0	-2.2	1.4	2.1	2.1
K content in liver	0.4	0.4	1.3	0.1	-0.5	0.5	0.3	0.4	-0.3	0.4	-0.7	1.1	1.1
Mg content in liver	1.2	1.2	2.2	-1.1	0.9	1.5	1.3	1.1	-1.3	1.2	-1.3	-0.0	-0.0
Mn content in liver	0.2	0.3	0.7	0.6	-0.4	-0.6	-0.7	-0.3	0.8	-0.2	0.8	0.0	0.0
Na content in liver	0.4	0.4	1.1	0.7	-1.0	0.1	-0.2	0.4	0.2	-0.0	-0.3	1.0	1.0
Rb content in liver	0.3	0.4	1.3	-0.4	0.3	0.8	0.4	1.1	-0.4	0.7	-0.4	-0.4	-0.4
Se content in liver	0.4	0.5	1.2	0.4	-0.4	-0.7	-0.3	-0.9	0.3	-1.0	0.2	1.1	1.1
Sr content in liver	1.7	1.4	2.7	-1.5	1.6	1.1	1.2	0.9	-1.1	1.1	-0.7	-1.2	-1.2
Zn content in liver	0.1	0.1	0.5	-0.2	0.5	-0.3	-0.0	-0.7	0.0	-0.7	0.3	-0.2	-0.2
Bone: minimum diameter	1.9	3.4	6.0	-1.7	1.9	2.3	1.3	2.5	-1.2	2.1	-0.7	-2.1	-2.1
Time in familiar zone, hab. session 1	0.8	0.7	1.7	1.0	-1.0	-0.5	-0.9	-0.9	0.9	-1.3	0.8	0.4	0.4
Time in novel zone, hab. session 1	0.3	0.3	0.9	-0.8	0.9	0.1	0.6	0.2	-0.6	0.6	-0.3	-0.3	-0.3
Total zone transitions, hab. session 1	0.1	0.2	0.6	0.4	-0.3	-0.8	-0.5	-0.3	0.5	-0.2	0.5	-0.2	-0.2
Total locomotion distance, hab. session 1	0.5	0.7	1.9	0.9	-0.8	-1.4	-1.0	-0.6	1.0	-0.4	1.0	-0.1	-0.1
Locomotion velocity, hab. session 1	0.2	0.3	0.7	0.5	-0.5	-0.8	-0.6	0.1	0.6	0.2	0.6	-0.4	-0.4
Time in familiar zone, hab. session 2	3.9	4.1	5.5	2.2	-2.3	-2.3	-1.8	-2.1	1.8	-2.3	1.3	1.9	1.9
Time in novel zone, hab. session 2	5.9	6.0	9.4	-2.9	3.1	2.7	2.4	2.1	-2.3	2.3	-1.6	-2.4	-2.4
Total zone transitions, hab. session 2	0.0	0.1	0.2	-0.1	0.3	-0.4	-0.0	-0.2	0.0	-0.3	0.2	-0.3	-0.3
Total locomotion distance, hab. session 2	0.2	0.2	0.4	0.0	0.3	-0.6	-0.3	-0.3	0.3	-0.4	0.6	-0.6	-0.6
Locomotion velocity, hab. session 2	0.1	0.1	0.3	0.1	0.2	-0.5	-0.3	-0.2	0.3	-0.4	0.5	-0.5	-0.5
Novel to familiar place preference ratio	0.1	0.1	0.3	0.3	-0.5	-0.5	-0.2	-0.1	0.1	0.0	-0.0	0.4	0.4
Novelty place preference	0.0	0.0	0.1	0.1	-0.2	-0.4	-0.1	0.0	0.1	0.1	0.0	0.1	0.1
Time in novel zone, NPP test	0.0	0.0	0.1	0.0	-0.0	-0.3	-0.0	0.0	0.0	0.2	0.0	-0.1	-0.1
Total zone transitions, NPP test	0.1	0.1	0.4	0.3	-0.4	-0.6	-0.1	-0.3	0.1	-0.1	-0.0	0.1	0.1
Total locomotion distance, NPP test	0.4	0.6	1.3	0.9	-1.0	-1.1	-0.6	-0.8	0.6	-0.7	0.3	0.7	0.7
Locomotion velocity, NPP test	0.7	1.0	1.8	1.1	-1.4	-1.3	-0.8	-0.9	0.7	-0.8	0.3	1.1	1.1
Intraocular pressure	0.2	0.3	0.7	-0.6	0.6	0.9	0.6	0.2	-0.6	0.2	-0.5	-0.2	-0.2
Delta distance traveled before/after self-admin	0.8	0.8	2.3	-0.7	0.3	0.9	1.2	0.8	-1.2	0.8	-1.5	0.4	0.4
Delta ambulatory time before/after self-admin	0.1	0.2	0.5	0.3	-0.6	-0.1	0.0	-0.2	-0.1	-0.2	-0.4	0.7	0.7
Parametrial fat weight	0.3	0.6	1.0	0.8	-0.9	-0.4	-0.6	-0.9	0.6	-0.9	0.3	1.0	1.0
Pavlov. Cond. lever latency	0.9	1.1	2.1	1.1	-1.0	-0.4	-1.2	-1.3	1.2	-1.4	1.1	0.8	0.8
Pavlov. Cond. magazine entry latency	0.8	1.0	2.4	0.9	-0.8	-1.6	-1.0	-1.3	1.0	-1.1	1.0	0.2	0.2
Pavlov. Cond. change in total contacts	0.0	0.0	0.1	0.1	-0.2	-0.4	0.1	-0.2	-0.1	0.3	-0.2	0.1	0.1
Pavlov. Cond. index score	0.1	0.1	0.8	0.2	-0.3	-0.9	-0.1	-0.2	0.1	0.1	0.0	-0.0	-0.0
Pavlov. Cond. latency score	0.1	0.1	0.6	-0.0	-0.0	-0.8	0.1	0.1	-0.1	0.3	-0.1	-0.2	-0.2
Pavlov. Cond. lever contacts	0.6	0.7	1.5	-0.8	0.7	0.2	0.9	1.1	-0.9	1.2	-0.8	-0.7	-0.7
Pavlov. Cond. magazine entry number	1.1	1.4	2.6	-1.3	1.1	1.6	1.3	1.4	-1.2	1.2	-1.1	-0.5	-0.5
Pavlov. Cond. intertrial magazine entries	0.2	0.2	0.5	-0.5	0.4	0.5	0.7	0.2	-0.7	-0.0	-0.7	0.2	0.2
Pavlov. Cond. lever-magazine prob. diff.	0.0	0.0	0.4	0.1	-0.1	-0.6	-0.0	-0.1	0.0	0.2	-0.0	-0.1	-0.1
Pavlov. Cond. response bias	0.1	0.2	0.6	0.4	-0.4	-0.8	-0.4	-0.5	0.4	-0.3	0.3	0.0	0.0
Pavlov. Cond. lever latency	0.4	0.5	1.0	-0.8	0.5	0.8	0.9	0.5	-0.9	0.6	-1.0	-0.4	-0.4
Pavlov. Cond. magazine entry latency	1.2	1.5	2.3	-1.4	1.3	1.5	1.3	1.2	-1.3	1.2	-1.1	-0.8	-0.8
Pavlov. Cond. change in total contacts	0.0	0.0	0.0	-0.1	0.1	-0.1	0.1	-0.2	-0.1	0.0	-0.1	0.1	0.1
Pavlov. Cond. index score	0.0	0.0	0.0	-0.1	0.2	-0.0	0.0	-0.1	-0.0	0.1	0.1	-0.1	-0.1
Pavlov. Cond. latency score	0.0	0.0	0.0	-0.1	0.2	-0.0	0.0	-0.0	0.0	0.1	0.1	-0.1	-0.1
Pavlov. Cond. lever contacts	0.7	1.0	1.4	1.1	-1.0	-1.1	-1.2	-0.9	1.2	-0.8	1.1	0.7	0.7
Pavlov. Cond. magazine entry number	1.7	2.1	3.0	1.7	-1.7	-1.5	-1.4	-1.4	1.4	-1.4	1.1	1.3	1.3
Pavlov. Cond. intertrial magazine entries	0.6	0.9	1.8	1.1	-0.9	-1.3	-1.1	-0.7	1.2	-0.6	1.1	0.5	0.5
Pavlov. Cond. lever-magazine prob. diff.	0.0	0.0	0.1	-0.2	0.3	0.0	0.1	0.0	-0.1	0.2	0.0	-0.1	-0.1
Pavlov. Cond. response bias	0.0	0.0	0.1	0.2	-0.1	-0.1	-0.2	-0.1	0.2	-0.0	0.3	0.1	0.1
Time in closed arm before self-admin	0.2	0.2	0.6	-0.5	0.6	0.4	0.2	0.3	-0.2	0.3	0.0	-0.8	-0.8
Time in closed arm after self-admin	0.3	0.4	0.6	0.6	-0.6	-0.7	-0.6	-0.7	0.6	-0.6	0.5	0.5	0.5
Time in open arm before self-admin	0.2	0.2	0.3	-0.5	0.6	0.4	0.3	0.5	-0.3	0.4	-0.1	-0.6	-0.6
Time in open arm after self-admin	1.6	1.8	2.2	-1.5	1.4	1.4	1.4	1.5	-1.4	1.4	-1.2	-1.0	-1.0
Bone: periosteal estimation	4.0	8.5	12.9	-2.9	3.0	3.5	2.5	3.6	-2.5	3.3	-1.8	-2.8	-2.8
Bone: periosteal perimeter	4.2	7.2	10.7	-2.8	2.7	3.0	2.6	3.3	-2.6	3.2	-2.1	-2.2	-2.2
Bone: post-yield work	0.5	0.8	1.3	0.8	-0.6	-1.0	-1.0	-1.1	1.0	-1.1	1.0	0.1	0.1
Progressive ratio test 1 active lever presses	0.8	1.0	1.6	-1.0	0.8	1.1	1.2	1.1	-1.2	1.1	-1.3	-0.5	-0.5
Progressive ratio test 1 breakpoint	0.8	1.0	1.7	-1.0	0.7	1.0	1.2	1.0	-1.2	1.0	-1.3	-0.4	-0.4
Progressive ratio test 1 inactive lever presses	0.2	0.2	0.3	-0.5	0.5	0.5	0.6	0.5	-0.6	0.5	-0.5	-0.3	-0.3
Progressive ratio test 2 active lever presses	0.1	0.1	0.3	-0.1	-0.2	0.2	0.3	0.2	-0.4	0.2	-0.6	0.4	0.4
Progressive ratio test 2 breakpoint	0.1	0.1	0.4	-0.1	-0.1	0.2	0.4	0.2	-0.4	0.2	-0.6	0.4	0.4
Progressive ratio test 2 inactive lever presses	0.3	0.6	1.0	-0.7	0.5	0.8	0.9	0.8	-0.9	0.8	-1.0	-0.2	-0.2
Incentive Sensitization - Responses	0.1	0.1	0.4	0.4	-0.5	-0.2	-0.1	-0.2	0.1	-0.2	-0.1	0.7	0.7
Incentive Sensitization - Breakpoint	0.1	0.1	0.3	0.3	-0.4	-0.2	-0.1	-0.2	0.1	-0.2	-0.1	0.6	0.6
Sum of active levers in priming session hrs 5-6	0.3	0.2	0.7	0.2	-0.5	-0.2	0.2	-0.2	-0.3	-0.1	-0.6	0.8	0.8
Progressive ratio	0.2	0.2	0.4	-0.5	0.4	0.6	0.5	0.6	-0.5	0.6	-0.5	-0.4	-0.4
Food seeking constrained by brief footshock	1.6	1.9	3.6	-1.5	1.4	1.4	1.5	1.2	-1.5	1.9	-1.3	-1.0	-1.0
Seeking ratio, punishment vs. effort	0.0	0.0	0.1	-0.1	0.2	-0.1	-0.0	-0.2	0.0	0.3	0.2	-0.4	-0.4
Retroperitoneal fat weight	0.4	1.8	3.7	-1.3	0.8	1.5	1.7	1.4	-1.7	1.3	-1.9	0.3	0.3
Reaction time number correct	1.1	2.1	6.8	-1.3	2.0	0.7	0.3	0.5	-0.2	0.5	0.7	-2.6	-2.6
Reaction time mean minus median	0.6	1.6	2.5	1.4	-1.3	-1.6	-1.3	-1.4	1.3	-1.3	1.1	0.7	0.7
Reaction time mean minus median AUC	0.0	0.1	0.2	-0.2	0.0	0.1	0.4	-0.1	-0.4	0.0	-0.5	0.2	0.2
Reaction time num false alarms	1.2	1.7	4.8	-0.9	0.2	1.3	1.7	1.2	-1.7	1.1	-2.2	0.8	0.8
Reaction time num false alarms AUC	1.5	2.3	6.4	-1.3	0.6	1.4	2.0	1.4	-2.1	1.2	-2.5	0.7	0.7
Reaction time trials correct on left	1.1	2.1	6.8	-1.3	2.0	0.7	0.3	0.5	-0.2	0.5	0.7	-2.6	-2.6
Reaction time trials on left	1.0	1.9	6.4	-1.2	1.9	0.6	0.2	0.4	-0.2	0.4	0.7	-2.5	-2.5
Reaction time mean	1.0	1.6	3.0	1.5	-1.7	-1.1	-1.1	-1.1	1.1	-1.2	0.6	1.5	1.5
Reaction time mean AUC	1.0	1.6	2.8	1.5	-1.7	-1.1	-1.0	-1.1	1.0	-1.2	0.5	1.5	1.5
Median of all reaction times	0.9	1.3	2.7	1.4	-1.6	-0.8	-0.9	-0.8	0.8	-0.9	0.3	1.5	1.5
Reaction time omissions	0.7	1.0	1.9	0.9	-1.0	-1.2	-0.7	-1.4	0.7	-1.3	0.5	1.0	1.0
Reaction time false alarm rate	1.6	2.2	6.5	-0.6	-0.4	1.0	1.7	0.9	-1.8	0.8	-2.6	1.8	1.8
Reaction time premature initiation rate	0.1	0.2	0.4	-0.1	-0.2	0.3	0.3	-0.2	-0.3	-0.2	-0.5	0.7	0.7
Reaction time premature initiations	0.1	0.3	0.7	-0.7	0.8	0.6	0.4	0.0	-0.4	-0.1	-0.1	-0.6	-0.6
Std. dev. reaction times	0.7	1.2	1.8	1.2	-1.4	-1.2	-0.8	-1.2	0.8	-1.2	0.4	1.2	1.2
Reaction time trials completed	1.0	1.9	6.4	-1.2	1.9	0.6	0.2	0.4	-0.2	0.4	0.7	-2.5	-2.5
Reaction time trials AUC	1.0	1.9	6.5	-1.2	1.9	0.5	0.2	0.3	-0.1	0.3	0.8	-2.5	-2.5
Run reversals in cocaine runway, females	1.8	1.8	4.4	1.4	-2.0	-1.0	-0.6	-1.0	0.5	-0.9	-0.3	2.1	2.1
Run reversals in cocaine runway, males	0.2	0.2	0.4	-0.6	0.4	0.6	0.6	0.1	-0.6	0.5	-0.6	0.0	0.0
Latency to leave start box in cocaine runway	1.1	1.2	1.9	-1.1	0.8	1.2	1.3	1.4	-1.3	1.0	-1.4	-0.6	-0.6
Latency to leave start box in cocaine runway, F	2.4	2.7	3.8	-1.8	1.5	1.7	1.9	1.8	-1.9	1.7	-1.9	-0.8	-0.8
Latency to leave start box in cocaine runway, M	0.0	0.0	0.1	0.1	-0.2	-0.0	-0.1	0.3	0.1	-0.4	-0.0	-0.2	-0.2
Std. dev. time between licks in bursts	0.2	0.3	0.8	0.3	-0.1	-0.3	-0.7	0.1	0.7	0.2	0.9	-0.7	-0.7
Total sessions with >9 infusions	0.1	0.1	0.3	-0.3	0.1	0.4	0.5	0.4	-0.5	0.4	-0.6	0.1	0.1
Short access day 1 total inactive lever presses	0.0	0.1	0.1	-0.3	0.4	0.2	0.1	0.2	-0.1	0.2	0.0	-0.4	-0.4
Short access day 10 total inactive lever presses	0.6	1.3	3.9	0.9	-0.3	-1.1	-1.5	-1.1	1.6	-1.1	2.0	-0.4	-0.4
Short access day 1 total infusions	0.1	0.1	0.4	-0.1	-0.2	0.2	0.4	0.2	-0.4	0.2	-0.6	0.4	0.4
Short access day 10 total infusions	0.0	0.0	0.1	-0.1	0.1	0.1	0.0	0.1	-0.0	0.1	0.0	-0.3	-0.3
Short access total infusions	0.0	0.0	0.0	0.0	-0.0	0.0	0.0	0.0	-0.0	0.0	-0.0	-0.0	-0.0
Short access day 1 locomotion	0.4	0.4	0.6	-0.7	0.6	0.7	0.8	0.7	-0.8	0.7	-0.8	-0.3	-0.3
Short access day 10 total locomotion	1.2	2.3	3.1	1.6	-1.4	-1.6	-1.8	-1.6	1.8	-1.6	1.7	0.8	0.8
Short access total locomotion	0.4	0.5	0.7	0.8	-0.7	-0.8	-0.8	-0.8	0.8	-0.8	0.8	0.4	0.4
One hour access (0.3 mA shock)	0.1	0.1	0.2	-0.2	0.4	0.2	0.0	0.2	-0.0	0.2	0.1	-0.5	-0.5
Compulsive drug intake	0.1	0.2	0.2	0.4	-0.4	-0.4	-0.4	-0.4	0.4	-0.4	0.3	0.4	0.4
One hour access (shock baseline)	0.0	0.0	0.1	-0.2	0.2	0.2	0.1	0.2	-0.1	0.2	-0.1	-0.3	-0.3
Social response proportion	1.4	1.6	3.1	1.1	-0.7	-1.5	-1.5	-1.4	1.6	-1.4	1.8	-0.0	-0.0
Social responses	0.3	0.4	1.2	-0.2	0.7	-0.0	-0.4	-0.2	0.4	-0.3	0.9	-1.1	-1.1
Social time	1.0	1.3	1.9	1.3	-1.2	-1.2	-1.4	-1.2	1.4	-1.1	1.2	0.6	0.6
Soleus weight	2.2	6.5	12.2	-3.1	3.5	2.4	2.3	1.8	-2.2	1.8	-1.3	-3.1	-3.1
Bone: stiffness	1.3	2.2	4.7	-1.2	1.0	1.9	1.4	2.2	-1.4	2.0	-1.3	-0.8	-0.8
Tibialis anterior weight	1.1	3.7	5.7	-2.4	2.3	1.6	2.2	1.6	-2.2	1.8	-1.8	-1.6	-1.6
Time to tail flick, vehicle, before self-admin	0.8	0.8	1.4	0.9	-1.2	-0.8	-0.6	-0.9	0.5	-0.9	0.1	1.2	1.2
Time to tail flick, vehicle, after self-admin	0.5	0.6	1.0	0.8	-0.9	-0.8	-0.6	-0.8	0.6	-0.9	0.4	1.0	1.0
Time to tail flick, test, before self-admin	0.1	0.1	0.2	-0.4	0.5	0.3	0.2	0.2	-0.2	0.3	-0.0	-0.4	-0.4
Time to tail flick, test, after self-admin	0.9	0.9	2.7	-0.8	1.3	0.6	0.3	0.7	-0.2	0.7	0.3	-1.6	-1.6
Delta time to tail flick, vehicle, before/after SA	0.1	0.1	0.2	-0.4	0.5	0.3	0.2	0.3	-0.2	0.3	-0.1	-0.4	-0.4
Delta time to tail flick, test, before/after SA	0.3	0.3	0.8	-0.1	0.5	0.0	-0.3	0.1	0.3	-0.1	0.7	-0.9	-0.9
Tibia length	1.6	4.4	10.4	-1.8	1.6	3.2	1.9	3.2	-1.9	2.3	-1.7	-1.0	-1.0
Ambulatory time before self-admin	0.7	1.1	1.9	1.2	-1.4	-1.0	-0.8	-0.9	0.7	-0.8	0.3	1.4	1.4
Ambulatory time after self-admin	1.4	1.6	3.9	1.3	-1.7	-1.0	-0.6	-1.0	0.6	-0.9	-0.1	2.0	2.0
Bone: tissue strength	2.4	2.4	6.3	-1.5	2.1	1.3	0.7	1.3	-0.6	1.0	0.2	-2.5	-2.5
Total heroin consumption	0.5	0.6	1.0	-0.9	0.9	0.5	0.7	0.5	-0.6	0.8	-0.4	-1.0	-1.0
Bone: trabecular number	0.4	0.7	1.1	0.9	-0.9	-0.7	-0.8	-1.1	0.8	-1.0	0.6	0.9	0.9
Bone: trabecular spacing	1.8	2.4	3.6	-1.6	1.7	1.8	1.3	1.9	-1.2	1.7	-0.8	-1.6	-1.6
Bone: trabecular thickness	1.1	1.4	2.9	1.2	-1.2	-1.7	-1.1	-1.5	1.1	-1.0	0.9	0.8	0.8
Bone: trabecular tissue density	0.1	0.2	0.5	0.6	-0.7	-0.3	-0.5	0.1	0.5	-0.1	0.3	0.4	0.4
Water consumed over 24 hours	1.3	1.7	4.9	1.0	-0.3	-0.9	-1.7	-0.9	1.8	-1.0	2.2	-1.1	-1.1
Number of responses in last shaping day	0.6	0.7	2.1	0.3	-0.9	-0.0	0.4	-0.0	-0.5	-0.0	-1.1	1.4	1.4