Hub : Genes

Adcy7

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Adcy7 0.03 0.02 6.2e-04 0.02 0.02 0.01 0.02 1.1e-03 1.6e-03 9.3e-03 1.0e-03
2 Brain alternative polyA NM_053396.1 0.4 0.19 8.1e-04 0.04 0.02 0.03 0.04 5.7e-05 4.7e-03 1.5e-03 2.3e-04
3 Brain alternative polyA XM_017601393.3 0.41 0.19 7.1e-04 0.04 0.02 0.03 0.04 6.0e-05 3.2e-03 1.4e-03 2.3e-04
4 Brain alternative polyA NM_053396.1 0.42 0.19 8.9e-04 0.04 0.02 0.02 0.03 7.4e-05 6.8e-03 2.5e-03 4.1e-04
5 Brain alternative polyA XM_017601393.3 0.41 0.19 5.7e-04 0.04 0.02 0.03 0.04 5.3e-05 5.5e-03 1.8e-03 3.1e-04
6 Brain alternative TSS XM_063278326.1 0.47 0.17 1.0e-03 0.02 0.03 0.03 0.03 4.0e-03 7.6e-04 1.1e-03 5.2e-04
7 NAcc gene expression Adcy7 0.03 0.02 3.8e-04 0.02 0.02 0.02 0.02 6.0e-04 5.8e-04 2.9e-04 5.5e-04
8 IL gene expression Adcy7 0.17 0.12 7.9e-03 0.08 0.08 0.09 0.08 5.1e-03 5.5e-03 3.6e-03 5.1e-03
9 PL gene expression Adcy7 0.11 0.06 2.0e-09 0.05 0.08 0.07 0.07 5.0e-06 6.2e-09 4.1e-08 9.1e-08
10 NAcc intron excision ratio chr19_34936794_34972128 0.02 0.02 9.1e-03 0 0 0 -0 1.1e-01 3.2e-01 3.6e-01 4.3e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density1.72.83.61.9-1.91.9-1.91.9-1.91.71.31.0-1.2
Area under the delay curve0.20.20.4-0.50.5-0.50.5-0.50.5-0.7-0.3-0.30.2
BMI with tail1.75.89.0-2.82.8-2.82.8-2.82.8-3.0-0.7-1.10.3
BMI without tail0.10.20.9-0.50.4-0.40.4-0.40.4-0.90.3-0.0-0.2
Body weight0.31.12.6-1.21.2-1.21.2-1.21.2-1.60.10.1-0.1
Weight adjusted by age2.13.15.9-2.12.0-2.02.0-2.02.0-2.4-0.4-0.6-0.2
Bone surface1.32.42.91.7-1.71.7-1.71.7-1.71.01.61.2-1.4
Bone volume2.85.06.12.4-2.52.5-2.52.5-2.51.62.11.9-1.8
Breakpoint value in progressive ratio session0.50.61.70.5-0.60.6-0.60.6-0.61.3-0.9-0.71.1
Number of licking bursts0.20.30.80.6-0.60.6-0.60.6-0.60.9-0.20.00.3
Context. condit. distance diff. score4.55.59.7-2.02.0-2.02.0-2.02.0-1.1-3.1-3.13.1
Locomotion velocity, session 10.60.71.00.9-0.90.9-0.90.9-0.90.50.61.0-0.6
Locomotion distance, session 10.30.31.2-0.20.2-0.20.2-0.20.20.4-1.1-0.71.1
Locomotion velocity, session 20.10.10.3-0.0-0.00.0-0.00.0-0.00.3-0.3-0.40.5
Locomotion distance, session 20.40.61.6-0.60.5-0.50.5-0.50.50.0-1.3-1.11.2
Locomotion velocity, session 31.11.23.1-1.21.2-1.21.2-1.21.2-1.8-0.4-0.60.3
Locomotion distance, session 30.20.30.5-0.50.5-0.50.5-0.50.5-0.7-0.6-0.30.4
Stereotopy head waving bouts, day 30.30.40.8-0.60.5-0.50.5-0.50.5-0.9-0.4-0.70.7
Stereotopy head waving duration, day 30.50.61.1-0.80.7-0.70.7-0.70.7-1.1-0.6-0.90.7
Locomotion velocity, session 71.71.94.3-1.01.1-1.11.1-1.11.1-0.3-2.0-2.11.8
Locomotion distance, session 70.70.92.40.4-0.30.3-0.30.3-0.31.1-1.5-1.51.5
Stereotopy head waving bouts, day 70.40.52.1-0.70.7-0.70.7-0.70.7-1.40.30.2-0.0
Stereotopy head waving duration, day 70.40.51.50.5-0.50.5-0.50.5-0.5-0.51.21.2-0.8
Locomotion velocity, session 81.72.06.4-0.70.7-0.70.7-0.70.70.0-2.5-2.42.3
Locomotion distance, session 82.84.010.7-1.31.3-1.31.3-1.31.3-0.2-3.2-3.03.3
Degree of sensitization distance0.50.51.20.5-0.50.5-0.50.5-0.51.1-0.7-1.11.0
Degree of sensitization stereotypy0.40.51.9-0.60.6-0.60.6-0.60.6-1.40.50.4-0.4
Conditioned locomotion0.00.10.20.1-0.10.1-0.10.1-0.10.30.50.3-0.4
Cocaine response after cond. corrected2.12.53.2-1.61.6-1.61.6-1.61.6-0.8-1.8-1.81.5
Cocaine response after cond. not corrected1.21.41.6-1.31.3-1.31.3-1.31.3-0.8-1.1-1.10.9
Cocaine response before conditioning2.22.64.31.6-1.61.6-1.61.6-1.60.71.92.1-1.6
Saline control response1.92.56.71.4-1.41.4-1.41.4-1.42.6-1.3-1.11.7
Bone: connectivity density1.21.93.01.6-1.61.6-1.61.6-1.61.70.60.2-0.5
Bone: cortical apparent density0.30.31.1-0.40.4-0.40.4-0.40.4-0.0-0.9-1.10.7
Bone: cortical area0.30.40.50.7-0.70.7-0.70.7-0.70.50.50.6-0.5
Bone: cortical porosity0.00.10.2-0.10.2-0.20.2-0.20.2-0.40.00.3-0.1
Bone: cortical porosity0.10.10.30.3-0.30.3-0.30.3-0.3-0.10.20.5-0.2
Bone: cortical thickness0.00.10.20.2-0.20.2-0.20.2-0.20.10.40.4-0.5
Bone: cortical thickness0.20.21.0-0.30.3-0.30.3-0.30.30.2-0.6-1.00.6
Bone: cortical tissue density0.30.51.4-0.50.5-0.50.5-0.50.5-0.1-1.0-1.20.8
Condit. Reinf. active minus inactive responses1.31.52.2-1.21.2-1.21.2-1.21.2-0.6-1.4-1.31.5
Condit. Reinf. active-inactive response ratio2.12.33.4-1.51.5-1.51.5-1.51.5-0.6-1.8-1.61.8
Condit. Reinf. active responses0.00.00.00.1-0.10.1-0.10.1-0.10.10.00.10.2
Condit. Reinf. inactive responses4.45.46.72.6-2.52.5-2.52.5-2.51.42.22.1-1.8
Incentive salience index mean0.10.20.50.3-0.30.3-0.30.3-0.30.7-0.5-0.10.7
Condit. Reinf. lever presses1.31.92.41.6-1.61.6-1.61.6-1.61.50.71.1-0.4
Condit. Reinf. active minus inactive responses0.10.10.2-0.40.4-0.40.4-0.40.4-0.5-0.2-0.10.0
Condit. Reinf. active-inactive response ratio0.70.82.4-0.50.5-0.50.5-0.50.5-1.11.21.1-1.6
Condit. Reinf. active responses0.00.00.2-0.10.1-0.10.1-0.10.1-0.2-0.4-0.30.3
Condit. Reinf. inactive responses0.50.62.6-0.10.1-0.10.1-0.10.10.0-1.4-1.41.6
Condit. Reinf. lever presses0.40.60.7-0.80.8-0.80.8-0.80.8-0.7-0.7-0.70.5
Condit. Reinf. lever reinforcers received0.10.20.5-0.40.4-0.40.4-0.40.4-0.7-0.3-0.20.2
Conditioned reinforcement - actives0.10.20.90.2-0.20.2-0.20.2-0.20.4-0.7-0.40.9
Conditioned reinforcement - inactives0.40.63.0-0.40.3-0.30.3-0.30.3-0.1-1.1-0.91.7
Conditioned locomotion0.10.10.10.3-0.30.3-0.30.3-0.30.4-0.3-0.20.3
Patch foraging indifference point 0 sec0.61.12.6-0.80.8-0.80.8-0.80.8-0.7-1.6-1.51.5
Patch foraging indifference point AUC0.71.11.41.2-1.21.2-1.21.2-1.21.20.40.8-0.5
Delay disc. indifference point, 0s delay0.90.91.31.1-1.11.1-1.11.1-1.11.00.50.9-0.2
Delay disc. indifference point, 16s delay0.50.51.2-0.80.8-0.80.8-0.80.8-1.1-0.1-0.3-0.0
Delay disc. indifference point, 2s delay0.30.41.4-0.50.4-0.40.4-0.40.4-1.20.70.4-0.8
Delay disc. indifference point, 24s delay0.00.00.0-0.0-0.10.1-0.10.1-0.1-0.1-0.00.1-0.0
Delay disc. indifference point, 4s delay0.30.31.0-0.30.3-0.30.3-0.30.30.1-1.0-0.90.9
Delay disc. indifference point, 8s delay0.70.81.0-1.01.0-1.01.0-1.01.0-1.0-0.8-0.70.7
Indifference point function ln k0.91.62.1-1.51.5-1.51.5-1.51.5-1.3-0.6-1.00.6
Indifference point function log k0.91.62.1-1.51.5-1.51.5-1.51.5-1.3-0.6-1.00.6
Patch foraging total patch changes 0 sec0.71.42.8-1.00.9-0.90.9-0.90.9-0.8-1.7-1.61.5
Patch foraging total patch changes 12 sec0.91.12.80.7-0.70.7-0.70.7-0.71.4-1.4-0.91.7
Patch foraging total patch changes 18 sec1.21.83.91.5-1.51.5-1.51.5-1.52.0-0.6-0.40.9
Patch foraging total patch changes 24 sec0.71.21.81.0-1.01.0-1.01.0-1.01.3-1.2-0.61.3
Patch foraging total patch changes 6 sec0.20.20.50.4-0.40.4-0.40.4-0.40.5-0.7-0.40.7
Patch foraging time to switch 0 sec0.00.10.30.0-0.00.0-0.00.0-0.00.2-0.4-0.30.5
Patch foraging water rate 0 sec0.10.20.60.4-0.40.4-0.40.4-0.40.10.50.6-0.8
Patch foraging water rate 12 sec0.40.81.00.9-0.90.9-0.90.9-0.90.71.00.8-1.0
Patch foraging water rate 18 sec2.74.27.51.8-1.81.8-1.81.8-1.81.02.62.7-2.6
Patch foraging water rate 24 sec0.10.10.50.1-0.10.1-0.10.1-0.10.00.50.5-0.7
Patch foraging water rate 6 sec3.14.56.02.4-2.42.4-2.42.4-2.42.21.31.2-1.0
Seeking ratio, delayed vs. immediate footshock4.55.57.0-2.62.7-2.72.7-2.72.7-2.3-1.7-1.91.3
Distance traveled before self-admin2.02.64.3-1.91.9-1.91.9-1.91.9-2.10.0-0.2-0.4
Distance traveled after self-admin0.81.03.5-0.30.3-0.30.3-0.30.3-1.01.71.5-1.9
Extensor digitorum longus weight0.31.24.40.2-0.20.2-0.20.2-0.2-0.52.01.8-2.1
Bone: elastic displacement0.10.10.3-0.10.1-0.10.1-0.10.10.2-0.5-0.40.4
Bone: elastic work0.00.00.10.1-0.10.1-0.10.1-0.1-0.00.20.3-0.4
Bone: endosteal estimation0.00.10.1-0.20.3-0.30.3-0.30.30.0-0.3-0.30.3
Bone: endosteal perimeter0.20.51.4-0.40.4-0.40.4-0.40.40.1-1.1-1.11.2
Epididymis fat weight0.20.81.1-1.00.9-0.90.9-0.90.9-0.9-0.9-0.50.7
Delta time in closed arm before/after self-admin0.30.30.4-0.60.6-0.60.6-0.60.6-0.6-0.4-0.50.3
Delta time in open arm before/after self-admin0.70.71.11.0-1.01.0-1.01.0-1.01.00.40.4-0.2
Diff in mean of infusions in LGA sessions0.91.13.6-0.20.2-0.20.2-0.20.20.8-1.8-1.81.9
Delay discount exponential model param0.10.20.40.4-0.40.4-0.40.4-0.40.60.40.4-0.2
Extinction: sum of active levers before priming3.43.85.3-2.32.2-2.22.2-2.22.2-2.1-1.0-1.40.6
Active lever presses in extinction session 60.20.20.6-0.30.3-0.30.3-0.30.3-0.30.70.4-0.8
Bone: final force1.82.85.01.6-1.61.6-1.61.6-1.60.82.02.2-1.9
Bone: final moment1.21.93.81.2-1.21.2-1.21.2-1.20.51.71.9-1.7
Food consumed during 24 hour testing period3.85.29.62.6-2.62.6-2.62.6-2.63.10.61.1-0.2
Glucose0.81.21.81.3-1.41.4-1.41.4-1.40.50.60.7-0.4
Heart weight1.01.52.8-1.21.1-1.11.1-1.11.1-0.9-1.3-1.71.2
Delay discount hyperbolic model param0.10.20.30.4-0.40.4-0.40.4-0.40.50.40.4-0.3
Intermittent access intake day 1-15 change2.55.17.52.6-2.62.6-2.62.6-2.62.70.51.30.0
Intermittent access intake escalation1.93.95.62.3-2.32.3-2.32.3-2.32.40.51.1-0.1
Intermittent access intake escalation 22.63.05.12.0-2.02.0-2.02.0-2.02.3-0.50.30.8
Intermitt. access day 1 inactive lever presses0.10.31.4-0.30.2-0.20.2-0.20.20.1-0.6-0.81.2
Intermitt. access day 15 inactive lever presses0.81.62.9-1.11.1-1.11.1-1.11.1-0.6-1.7-1.61.7
Intermitt. access escalation Index0.10.20.3-0.40.4-0.40.4-0.40.4-0.5-0.4-0.30.0
Intermittent access day 1 total infusions1.11.82.7-1.61.5-1.51.5-1.51.5-1.6-0.6-0.80.4
Intermittent access day 15 total infusions0.00.00.0-0.00.0-0.00.0-0.00.0-0.10.10.2-0.1
Intermittent access terminal intake (last 3 days)0.10.20.6-0.30.3-0.30.3-0.30.3-0.2-0.8-0.50.7
Intermittent access total infusions0.00.00.1-0.10.1-0.10.1-0.10.1-0.2-0.3-0.10.2
Intermittent access day 1 locomotion0.30.41.3-0.20.2-0.20.2-0.20.2-0.61.10.7-1.1
Intermittent access day 15 total locomotion0.30.51.8-0.30.3-0.30.3-0.30.3-0.71.21.1-1.3
Intermittent access total locomotion0.20.30.8-0.10.2-0.20.2-0.20.2-0.50.80.9-0.9
Intermittent access standard deviation0.61.32.11.3-1.31.3-1.31.3-1.31.4-0.40.30.4
Left kidney weight0.73.23.81.9-1.91.9-1.91.9-1.91.61.61.9-1.2
Right kidney weight0.20.71.01.0-1.01.0-1.01.0-1.00.70.51.0-0.1
Cocaine induced anxiety1.62.26.1-1.01.0-1.01.0-1.01.0-0.3-2.5-2.12.5
Post-drug Anxiety1.11.22.8-0.80.8-0.80.8-0.80.8-0.3-1.7-1.51.6
Baseline Anxiety0.70.82.50.6-0.60.6-0.60.6-0.60.11.61.3-1.6
Tail length1.14.25.52.3-2.32.3-2.32.3-2.31.91.41.5-0.9
Length with tail0.20.91.61.0-1.01.0-1.01.0-1.00.70.81.3-0.6
Length without tail0.10.40.6-0.80.8-0.80.8-0.80.8-0.8-0.10.10.1
Times rat made contact with spout0.20.30.80.3-0.30.3-0.30.3-0.30.00.90.8-0.9
Lifetime Intake0.10.10.50.0-0.00.0-0.00.0-0.00.1-0.7-0.30.7
Liver weight, left0.10.20.30.5-0.50.5-0.50.5-0.50.5-0.3-0.00.6
Liver weight, right0.10.10.80.1-0.00.0-0.00.0-0.0-0.30.60.9-0.4
Locomotor activity0.10.10.6-0.10.0-0.00.0-0.00.0-0.80.60.4-0.6
Locomotor testing distance0.00.10.3-0.10.1-0.10.1-0.10.1-0.50.1-0.30.3
Locomotor testing rearing0.50.92.10.8-0.80.8-0.80.8-0.81.3-1.0-0.71.4
Locomotion in novel chamber0.30.40.5-0.70.7-0.70.7-0.70.7-0.7-0.6-0.30.6
Locomotion in novel chamber post-restriction0.50.81.90.8-0.80.8-0.80.8-0.80.71.41.1-0.9
Fecal boli incidents, locomotor time 10.60.82.10.9-0.90.9-0.90.9-0.91.4-0.5-0.30.9
Change in fecal boli incidents, locomotor task0.20.20.7-0.00.0-0.00.0-0.00.00.2-0.8-0.70.7
Time >=10cm from walls, locomotor time 10.60.61.50.7-0.60.6-0.60.6-0.6-0.21.11.2-1.1
Bouts of movement, locomotor time 10.40.41.40.8-0.70.7-0.70.7-0.71.20.1-0.10.1
Total resting periods, locomotor time 10.20.20.90.4-0.30.3-0.30.3-0.31.0-0.1-0.40.3
Rest time, locomotor task time 10.20.30.50.6-0.50.5-0.50.5-0.50.70.50.2-0.3
Distance moved, locomotor task time 10.40.60.7-0.90.9-0.90.9-0.90.9-0.7-0.6-0.70.4
Vertical activity count, locomotor time 10.20.50.70.8-0.80.8-0.80.8-0.80.60.20.50.0
Time >=10cm from walls, locomotor time 20.50.71.4-0.70.7-0.70.7-0.70.7-1.10.90.9-1.2
Bouts of movement, locomotor time 20.10.10.1-0.40.4-0.40.4-0.40.4-0.10.1-0.3-0.1
Total resting periods, locomotor time 20.00.10.3-0.10.1-0.10.1-0.10.10.3-0.2-0.60.3
Rest time, locomotor task time 20.40.41.40.4-0.40.4-0.40.4-0.41.0-0.7-1.20.9
Distance moved, locomotor task time 21.61.93.6-1.51.6-1.61.6-1.61.6-1.90.10.3-0.5
Vertical activity count, locomotor time 20.20.20.60.6-0.50.5-0.50.5-0.50.20.10.70.1
Light reinforcement 18.420.627.75.3-5.25.2-5.25.2-5.25.22.12.9-1.0
Light reinforcement 27.711.915.84.0-4.04.0-4.04.0-4.03.81.92.4-1.3
Bone: marrow area0.00.10.1-0.30.3-0.30.3-0.30.3-0.0-0.3-0.40.3
Bone: maximum diameter0.20.30.3-0.60.6-0.60.6-0.60.6-0.4-0.5-0.50.5
Bone: maximum force0.30.61.20.6-0.60.6-0.60.6-0.60.41.01.0-1.1
Bone: maximum moment0.10.20.70.3-0.30.3-0.30.3-0.30.20.70.7-0.9
Mean time between licks in bursts0.10.31.3-0.30.2-0.20.2-0.20.2-0.3-1.1-0.61.1
Mean num. licks in bursts0.20.30.9-0.40.4-0.40.4-0.40.4-0.80.80.5-1.0
Cd content in liver4.34.76.0-2.22.3-2.32.3-2.32.3-0.6-2.4-2.42.1
Co content in liver1.72.02.5-1.61.6-1.61.6-1.61.6-1.0-1.2-1.21.1
Cu content in liver0.10.10.3-0.10.1-0.10.1-0.10.1-0.30.40.5-0.3
Fe content in liver3.94.812.51.5-1.51.5-1.51.5-1.50.33.53.3-3.4
K content in liver1.21.12.1-1.01.0-1.01.0-1.01.0-1.50.90.8-1.1
Mg content in liver0.60.61.4-0.80.8-0.80.8-0.80.8-1.20.10.1-0.1
Mn content in liver1.31.52.7-1.11.1-1.11.1-1.11.1-0.6-1.6-1.71.3
Na content in liver1.01.03.50.1-0.10.1-0.10.1-0.1-0.61.91.7-1.9
Rb content in liver0.70.81.11.0-1.01.0-1.01.0-1.00.60.70.8-0.4
Se content in liver2.93.57.21.6-1.51.5-1.51.5-1.50.62.72.7-2.4
Sr content in liver0.50.40.6-0.70.8-0.80.8-0.80.8-0.6-0.3-0.20.2
Zn content in liver1.92.12.8-1.61.7-1.71.7-1.71.7-1.6-0.7-0.90.4
Bone: minimum diameter0.81.51.71.3-1.31.3-1.31.3-1.31.21.01.1-0.9
Time in familiar zone, hab. session 10.40.30.70.6-0.60.6-0.60.6-0.60.80.20.6-0.0
Time in novel zone, hab. session 10.50.51.0-0.70.6-0.60.6-0.60.6-1.00.6-0.1-0.8
Total zone transitions, hab. session 10.20.20.5-0.40.4-0.40.4-0.40.4-0.2-0.7-0.70.6
Total locomotion distance, hab. session 10.40.61.1-0.80.8-0.80.8-0.80.8-0.4-0.9-1.10.6
Locomotion velocity, hab. session 10.40.51.1-0.70.7-0.70.7-0.70.7-0.4-1.0-1.10.7
Time in familiar zone, hab. session 21.61.72.91.4-1.51.5-1.51.5-1.51.7-0.6-0.30.8
Time in novel zone, hab. session 23.53.55.1-2.22.2-2.22.2-2.22.2-2.20.2-0.4-0.4
Total zone transitions, hab. session 20.10.20.70.2-0.20.2-0.20.2-0.20.4-0.6-0.60.8
Total locomotion distance, hab. session 20.10.10.5-0.20.1-0.10.1-0.10.10.1-0.6-0.70.7
Locomotion velocity, hab. session 20.00.00.10.1-0.10.1-0.10.1-0.10.3-0.2-0.30.3
Novel to familiar place preference ratio1.21.42.0-1.41.4-1.41.4-1.41.4-1.2-0.2-0.4-0.3
Novelty place preference1.01.11.6-1.31.3-1.31.3-1.31.3-1.0-0.0-0.4-0.4
Time in novel zone, NPP test1.01.11.4-1.21.2-1.21.2-1.21.2-1.20.40.1-0.8
Total zone transitions, NPP test0.10.20.80.2-0.20.2-0.20.2-0.20.0-0.6-0.30.9
Total locomotion distance, NPP test0.00.00.2-0.20.1-0.10.1-0.10.1-0.50.1-0.0-0.1
Locomotion velocity, NPP test0.00.00.20.0-0.10.1-0.10.1-0.1-0.0-0.3-0.30.5
Intraocular pressure4.46.47.9-2.72.8-2.82.8-2.82.8-2.1-2.1-2.41.5
Delta distance traveled before/after self-admin2.52.73.31.7-1.71.7-1.71.7-1.71.21.61.8-1.4
Delta ambulatory time before/after self-admin3.24.05.02.2-2.22.2-2.22.2-2.21.81.51.9-1.1
Parametrial fat weight0.30.73.00.0-0.00.0-0.00.0-0.00.5-1.7-1.11.7
Pavlov. Cond. lever latency0.20.20.8-0.10.1-0.10.1-0.10.10.2-0.8-0.80.9
Pavlov. Cond. magazine entry latency0.10.10.3-0.30.3-0.30.3-0.30.3-0.30.50.3-0.5
Pavlov. Cond. change in total contacts1.31.43.11.0-0.90.9-0.90.9-0.90.51.81.6-1.6
Pavlov. Cond. index score0.20.20.3-0.40.5-0.50.5-0.50.5-0.50.50.4-0.5
Pavlov. Cond. latency score0.10.10.2-0.40.4-0.40.4-0.40.4-0.30.10.1-0.2
Pavlov. Cond. lever contacts0.20.20.80.00.0-0.00.0-0.00.0-0.40.90.8-0.9
Pavlov. Cond. magazine entry number0.40.51.30.3-0.30.3-0.30.3-0.30.8-1.1-1.01.1
Pavlov. Cond. intertrial magazine entries0.10.10.30.0-0.00.0-0.00.0-0.0-0.2-0.5-0.40.5
Pavlov. Cond. lever-magazine prob. diff.0.30.40.5-0.60.6-0.60.6-0.60.6-0.70.50.4-0.6
Pavlov. Cond. response bias0.60.82.6-0.00.0-0.00.0-0.00.0-0.81.61.4-1.6
Pavlov. Cond. lever latency0.30.40.5-0.70.7-0.70.7-0.70.7-0.60.1-0.3-0.2
Pavlov. Cond. magazine entry latency0.10.10.30.2-0.20.2-0.20.2-0.20.4-0.5-0.10.5
Pavlov. Cond. change in total contacts0.00.00.20.1-0.10.1-0.10.1-0.1-0.10.10.4-0.2
Pavlov. Cond. index score0.00.00.10.2-0.20.2-0.20.2-0.20.1-0.10.30.1
Pavlov. Cond. latency score0.00.00.10.2-0.20.2-0.20.2-0.20.2-0.10.30.0
Pavlov. Cond. lever contacts0.60.81.11.0-1.11.1-1.11.1-1.10.80.10.60.1
Pavlov. Cond. magazine entry number0.00.00.00.0-0.00.0-0.00.0-0.0-0.00.2-0.1-0.2
Pavlov. Cond. intertrial magazine entries0.60.81.21.1-1.11.1-1.11.1-1.11.00.30.3-0.0
Pavlov. Cond. lever-magazine prob. diff.0.00.00.10.2-0.20.2-0.20.2-0.20.1-0.10.30.0
Pavlov. Cond. response bias0.20.30.40.7-0.70.7-0.70.7-0.70.30.10.50.0
Time in closed arm before self-admin3.24.15.12.3-2.22.2-2.22.2-2.21.61.82.1-1.5
Time in closed arm after self-admin1.41.51.71.3-1.21.2-1.21.2-1.20.91.31.3-1.1
Time in open arm before self-admin2.12.32.7-1.61.6-1.61.6-1.61.6-1.1-1.6-1.41.3
Time in open arm after self-admin0.80.81.1-1.11.0-1.01.0-1.01.0-1.1-0.5-0.60.3
Bone: periosteal estimation0.10.10.20.4-0.40.4-0.40.4-0.40.50.10.1-0.1
Bone: periosteal perimeter0.10.20.8-0.10.1-0.10.1-0.10.10.0-0.7-0.90.9
Bone: post-yield work0.00.10.3-0.20.1-0.10.1-0.10.10.2-0.3-0.60.1
Progressive ratio test 1 active lever presses0.10.20.5-0.10.1-0.10.1-0.10.1-0.30.70.7-0.6
Progressive ratio test 1 breakpoint0.20.20.6-0.10.1-0.10.1-0.10.1-0.30.80.8-0.7
Progressive ratio test 1 inactive lever presses0.10.10.2-0.40.3-0.30.3-0.30.3-0.3-0.2-0.00.4
Progressive ratio test 2 active lever presses0.10.10.1-0.30.3-0.30.3-0.30.3-0.30.00.2-0.2
Progressive ratio test 2 breakpoint0.10.10.2-0.40.4-0.40.4-0.40.4-0.40.00.1-0.2
Progressive ratio test 2 inactive lever presses0.91.51.9-1.31.2-1.21.2-1.21.2-1.0-1.4-1.21.1
Incentive Sensitization - Responses0.10.20.8-0.20.3-0.30.3-0.30.30.1-0.9-0.60.6
Incentive Sensitization - Breakpoint0.10.20.7-0.20.2-0.20.2-0.20.20.2-0.9-0.60.6
Sum of active levers in priming session hrs 5-60.30.30.6-0.50.5-0.50.5-0.50.5-0.1-0.6-0.80.5
Progressive ratio0.20.30.40.6-0.60.6-0.60.6-0.60.50.00.0-0.4
Food seeking constrained by brief footshock2.02.53.81.8-1.91.9-1.91.9-1.92.00.20.6-0.3
Seeking ratio, punishment vs. effort0.71.01.31.1-1.11.1-1.11.1-1.11.10.71.0-0.2
Retroperitoneal fat weight0.72.98.6-1.11.0-1.01.0-1.01.0-0.2-2.8-2.42.9
Reaction time number correct0.30.61.3-0.90.8-0.80.8-0.80.8-1.1-0.3-0.4-0.1
Reaction time mean minus median0.51.33.0-1.21.2-1.21.2-1.21.2-1.70.80.5-0.8
Reaction time mean minus median AUC0.61.52.6-1.41.4-1.41.4-1.41.4-1.60.50.2-0.5
Reaction time num false alarms4.36.16.7-2.62.6-2.62.6-2.62.6-2.0-2.5-2.42.3
Reaction time num false alarms AUC3.35.15.6-2.42.3-2.32.3-2.32.3-1.9-2.3-2.32.1
Reaction time trials correct on left0.30.61.3-0.90.8-0.80.8-0.80.8-1.1-0.3-0.4-0.1
Reaction time trials on left0.40.71.5-0.90.9-0.90.9-0.90.9-1.2-0.3-0.5-0.1
Reaction time mean2.94.66.6-2.52.6-2.62.6-2.62.6-2.40.2-0.0-0.5
Reaction time mean AUC2.84.56.6-2.52.6-2.62.6-2.62.6-2.40.1-0.1-0.4
Median of all reaction times3.04.26.2-2.42.5-2.52.5-2.52.5-2.20.1-0.1-0.3
Reaction time omissions1.72.44.0-1.81.8-1.81.8-1.81.8-2.0-0.8-0.80.5
Reaction time false alarm rate1.82.43.6-1.51.5-1.51.5-1.51.5-1.0-1.8-1.71.9
Reaction time premature initiation rate3.04.18.62.3-2.32.3-2.32.3-2.32.9-0.9-0.21.1
Reaction time premature initiations1.12.04.01.5-1.51.5-1.51.5-1.52.0-1.1-0.51.1
Std. dev. reaction times1.01.83.2-1.51.5-1.51.5-1.51.5-1.80.40.2-0.5
Reaction time trials completed0.40.71.5-0.90.9-0.90.9-0.90.9-1.2-0.3-0.5-0.1
Reaction time trials AUC0.40.81.6-1.01.0-1.01.0-1.01.0-1.3-0.4-0.5-0.1
Run reversals in cocaine runway, females0.20.20.7-0.50.5-0.50.5-0.50.5-0.80.20.1-0.3
Run reversals in cocaine runway, males0.20.20.3-0.50.5-0.50.5-0.50.5-0.50.50.1-0.5
Latency to leave start box in cocaine runway0.40.50.7-0.80.8-0.80.8-0.80.8-0.3-0.4-0.80.6
Latency to leave start box in cocaine runway, F0.80.91.2-1.11.1-1.11.1-1.11.1-1.00.6-0.2-0.6
Latency to leave start box in cocaine runway, M1.00.93.30.2-0.20.2-0.20.2-0.21.3-1.6-1.21.8
Std. dev. time between licks in bursts0.10.20.30.5-0.50.5-0.50.5-0.50.5-0.10.20.3
Total sessions with >9 infusions0.00.00.1-0.10.1-0.10.1-0.10.1-0.20.30.2-0.1
Short access day 1 total inactive lever presses0.10.10.40.2-0.20.2-0.20.2-0.20.00.40.6-0.1
Short access day 10 total inactive lever presses0.10.30.60.5-0.60.6-0.60.6-0.60.8-0.5-0.10.7
Short access day 1 total infusions0.50.60.9-0.90.9-0.90.9-0.90.9-0.9-0.4-0.50.4
Short access day 10 total infusions0.10.10.5-0.0-0.00.0-0.00.0-0.00.2-0.5-0.40.7
Short access total infusions0.10.10.6-0.20.2-0.20.2-0.20.2-0.1-0.5-0.40.7
Short access day 1 locomotion1.61.92.7-1.61.6-1.61.6-1.61.6-1.6-0.6-0.80.4
Short access day 10 total locomotion0.00.10.1-0.30.3-0.30.3-0.30.3-0.40.10.0-0.0
Short access total locomotion0.40.50.6-0.80.8-0.80.8-0.80.8-0.7-0.4-0.50.3
One hour access (0.3 mA shock)1.21.44.7-0.60.6-0.60.6-0.60.60.0-2.2-1.92.0
Compulsive drug intake0.30.41.7-0.10.2-0.20.2-0.20.20.3-0.9-1.31.1
One hour access (shock baseline)0.30.51.5-0.50.4-0.40.4-0.40.4-0.2-1.2-1.01.0
Social response proportion0.20.30.3-0.60.6-0.60.6-0.60.6-0.30.40.5-0.6
Social responses0.70.92.4-0.60.6-0.60.6-0.60.60.3-1.5-1.31.6
Social time0.50.70.90.9-0.80.8-0.80.8-0.81.00.80.7-0.6
Soleus weight0.10.41.20.2-0.30.3-0.30.3-0.30.3-1.0-1.01.1
Bone: stiffness0.40.61.50.5-0.50.5-0.50.5-0.50.01.21.1-1.2
Tibialis anterior weight0.41.32.2-1.31.3-1.31.3-1.31.3-1.50.2-0.1-0.4
Time to tail flick, vehicle, before self-admin0.20.21.0-0.1-0.00.0-0.00.0-0.00.3-0.7-1.00.7
Time to tail flick, vehicle, after self-admin0.50.71.60.6-0.50.5-0.50.5-0.51.3-1.0-0.91.2
Time to tail flick, test, before self-admin1.21.21.5-1.21.2-1.21.2-1.21.2-0.9-0.9-1.10.7
Time to tail flick, test, after self-admin1.21.22.31.1-1.01.0-1.01.0-1.00.61.51.2-1.4
Delta time to tail flick, vehicle, before/after SA0.20.20.50.5-0.40.4-0.40.4-0.40.7-0.3-0.10.4
Delta time to tail flick, test, before/after SA3.03.16.81.4-1.41.4-1.41.4-1.40.32.62.5-2.5
Tibia length0.51.44.7-0.0-0.00.0-0.00.0-0.0-1.42.01.9-2.2
Ambulatory time before self-admin2.03.04.7-2.02.0-2.02.0-2.02.0-2.2-0.2-0.5-0.2
Ambulatory time after self-admin0.80.92.90.4-0.40.4-0.40.4-0.4-0.21.71.6-1.7
Bone: tissue strength0.10.10.2-0.30.3-0.30.3-0.30.3-0.10.20.4-0.4
Total heroin consumption0.40.51.0-0.70.7-0.70.7-0.70.7-0.2-1.0-0.80.9
Bone: trabecular number1.72.73.41.8-1.91.9-1.91.9-1.91.51.40.9-1.3
Bone: trabecular spacing1.92.53.4-1.71.9-1.91.9-1.91.9-1.2-1.3-0.91.1
Bone: trabecular thickness4.05.05.92.2-2.32.3-2.32.3-2.31.42.42.2-2.3
Bone: trabecular tissue density0.50.81.1-1.01.1-1.11.1-1.11.1-1.0-0.2-0.20.0
Water consumed over 24 hours1.52.13.01.6-1.61.6-1.61.6-1.61.70.81.2-0.6
Number of responses in last shaping day1.82.03.1-1.41.4-1.41.4-1.41.4-1.1-1.8-1.61.5