Hub : Genes

Adcy7

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Adcy7 0.03 0.02 6.2e-04 0.02 0.02 0.01 0.02 1.1e-03 1.6e-03 9.3e-03 9.5e-04
2 Brain alternative polyA NM_053396.1 0.4 0.19 8.1e-04 0.04 0.02 0.03 0.04 5.7e-05 4.7e-03 1.5e-03 2.3e-04
3 Brain alternative polyA XM_017601393.3 0.41 0.19 7.1e-04 0.04 0.02 0.03 0.04 6.0e-05 3.2e-03 1.3e-03 2.3e-04
4 Brain alternative polyA NM_053396.1 0.42 0.19 8.9e-04 0.04 0.02 0.02 0.03 7.4e-05 6.8e-03 2.4e-03 3.9e-04
5 Brain alternative polyA XM_017601393.3 0.41 0.19 5.7e-04 0.04 0.02 0.03 0.04 5.3e-05 5.5e-03 1.8e-03 3.2e-04
6 Brain alternative TSS XM_063278326.1 0.47 0.17 1.0e-03 0.02 0.03 0.03 0.03 4.0e-03 7.6e-04 1.2e-03 5.2e-04
7 NAcc gene expression Adcy7 0.03 0.02 3.8e-04 0.02 0.02 0.02 0.02 6.0e-04 5.8e-04 2.9e-04 5.7e-04
8 IL gene expression Adcy7 0.17 0.12 7.9e-03 0.08 0.08 0.09 0.08 5.1e-03 5.5e-03 3.7e-03 5.8e-03
9 PL gene expression Adcy7 0.11 0.06 2.0e-09 0.05 0.08 0.07 0.07 5.0e-06 6.2e-09 4.1e-08 8.4e-08
10 NAcc intron excision ratio chr19_34936794_34972128 0.02 0.02 9.1e-03 0 0 0 -0 1.1e-01 3.2e-01 3.6e-01 4.2e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density1.52.83.61.91.9-1.91.9-1.9-1.9-1.7-1.31.01.2
Area under the delay curve0.10.20.4-0.5-0.50.5-0.50.50.50.70.3-0.3-0.2
BMI with tail1.65.89.0-2.8-2.82.8-2.82.82.83.00.7-1.1-0.3
BMI without tail0.00.20.9-0.5-0.40.4-0.40.40.40.9-0.3-0.00.2
Body weight0.31.12.6-1.2-1.21.2-1.21.21.21.6-0.10.10.1
Weight adjusted by age1.13.15.9-2.1-2.02.0-2.02.02.02.40.4-0.60.2
Bone surface1.22.42.91.71.7-1.71.7-1.7-1.7-1.0-1.61.21.4
Bone volume2.55.06.12.42.5-2.52.5-2.5-2.5-1.6-2.11.91.8
Breakpoint value in progressive ratio session0.30.61.70.50.6-0.60.6-0.6-0.6-1.30.9-0.7-1.1
Number of licking bursts0.10.30.80.60.6-0.60.6-0.6-0.6-0.90.20.0-0.3
Context. condit. distance diff. score4.55.59.7-2.0-2.02.0-2.02.02.01.13.1-3.1-3.1
Locomotion velocity, session 10.60.71.00.90.9-0.90.9-0.9-0.9-0.5-0.61.00.6
Locomotion distance, session 10.30.31.2-0.2-0.20.2-0.20.20.2-0.41.1-0.7-1.1
Locomotion velocity, session 20.10.10.3-0.00.0-0.00.0-0.0-0.0-0.30.3-0.4-0.5
Locomotion distance, session 20.40.61.6-0.6-0.50.5-0.50.50.5-0.01.3-1.1-1.2
Locomotion velocity, session 31.11.23.1-1.2-1.21.2-1.21.21.21.80.4-0.6-0.3
Locomotion distance, session 30.20.30.5-0.5-0.50.5-0.50.50.50.70.6-0.3-0.4
Stereotopy head waving bouts, day 30.30.40.8-0.6-0.50.5-0.50.50.50.90.4-0.7-0.7
Stereotopy head waving duration, day 30.50.61.1-0.8-0.70.7-0.70.70.71.10.6-0.9-0.7
Locomotion velocity, session 71.71.94.3-1.0-1.11.1-1.11.11.10.32.0-2.1-1.8
Locomotion distance, session 70.70.92.40.40.3-0.30.3-0.3-0.3-1.11.5-1.5-1.5
Stereotopy head waving bouts, day 70.40.52.1-0.7-0.70.7-0.70.70.71.4-0.30.20.0
Stereotopy head waving duration, day 70.40.51.50.50.5-0.50.5-0.5-0.50.5-1.21.20.8
Locomotion velocity, session 81.72.06.4-0.7-0.70.7-0.70.70.7-0.02.5-2.4-2.3
Locomotion distance, session 82.84.010.7-1.3-1.31.3-1.31.31.30.23.2-3.0-3.3
Degree of sensitization distance0.50.51.20.50.5-0.50.5-0.5-0.5-1.10.7-1.1-1.0
Degree of sensitization stereotypy0.40.51.9-0.6-0.60.6-0.60.60.61.4-0.50.40.4
Conditioned locomotion0.00.10.20.10.1-0.10.1-0.1-0.1-0.3-0.50.30.4
Cocaine response after cond. corrected1.72.53.2-1.6-1.61.6-1.61.61.60.81.8-1.8-1.5
Cocaine response after cond. not corrected0.91.41.6-1.3-1.31.3-1.31.31.30.81.1-1.1-0.9
Cocaine response before conditioning2.22.64.31.61.6-1.61.6-1.6-1.6-0.7-1.92.11.6
Saline control response1.82.56.71.41.4-1.41.4-1.4-1.4-2.61.3-1.1-1.7
Bone: connectivity density1.21.93.01.61.6-1.61.6-1.6-1.6-1.7-0.60.20.5
Bone: cortical apparent density0.20.31.1-0.4-0.40.4-0.40.40.40.00.9-1.1-0.7
Bone: cortical area0.30.40.50.70.7-0.70.7-0.7-0.7-0.5-0.50.60.5
Bone: cortical porosity0.00.10.2-0.1-0.20.2-0.20.20.20.4-0.00.30.1
Bone: cortical porosity0.10.10.30.30.3-0.30.3-0.3-0.30.1-0.20.50.2
Bone: cortical thickness0.00.10.20.20.2-0.20.2-0.2-0.2-0.1-0.40.40.5
Bone: cortical thickness0.20.21.0-0.3-0.30.3-0.30.30.3-0.20.6-1.0-0.6
Bone: cortical tissue density0.30.51.4-0.5-0.50.5-0.50.50.50.11.0-1.2-0.8
Condit. Reinf. active minus inactive responses1.31.52.2-1.2-1.21.2-1.21.21.20.61.4-1.3-1.5
Condit. Reinf. active-inactive response ratio2.12.33.4-1.5-1.51.5-1.51.51.50.61.8-1.6-1.8
Condit. Reinf. active responses0.00.00.00.10.1-0.10.1-0.1-0.1-0.1-0.00.1-0.2
Condit. Reinf. inactive responses4.15.46.72.62.5-2.52.5-2.5-2.5-1.4-2.22.11.8
Incentive salience index mean0.10.20.50.30.3-0.30.3-0.3-0.3-0.70.4-0.1-0.7
Condit. Reinf. lever presses1.21.92.41.61.6-1.61.6-1.6-1.6-1.5-0.71.10.4
Condit. Reinf. active minus inactive responses0.10.10.2-0.4-0.40.4-0.40.40.40.50.2-0.1-0.0
Condit. Reinf. active-inactive response ratio0.50.82.4-0.5-0.50.5-0.50.50.51.1-1.21.11.6
Condit. Reinf. active responses0.00.00.2-0.1-0.10.1-0.10.10.10.20.4-0.3-0.3
Condit. Reinf. inactive responses0.40.62.6-0.1-0.10.1-0.10.10.1-0.01.4-1.4-1.6
Condit. Reinf. lever presses0.40.60.7-0.8-0.80.8-0.80.80.80.70.7-0.7-0.5
Condit. Reinf. lever reinforcers received0.10.20.5-0.4-0.40.4-0.40.40.40.70.3-0.2-0.2
Conditioned reinforcement - actives0.00.20.90.20.2-0.20.2-0.2-0.2-0.40.7-0.4-0.9
Conditioned reinforcement - inactives0.20.63.0-0.4-0.30.3-0.30.30.30.11.1-0.9-1.7
Conditioned locomotion0.10.10.10.30.3-0.30.3-0.3-0.3-0.40.3-0.2-0.3
Patch foraging indifference point 0 sec0.41.12.6-0.8-0.80.8-0.80.80.80.71.6-1.5-1.5
Patch foraging indifference point AUC0.41.11.41.21.2-1.21.2-1.2-1.2-1.2-0.40.80.5
Delay disc. indifference point, 0s delay0.80.91.31.11.1-1.11.1-1.1-1.1-1.0-0.50.90.2
Delay disc. indifference point, 16s delay0.40.51.2-0.8-0.80.8-0.80.80.81.10.1-0.30.0
Delay disc. indifference point, 2s delay0.30.41.4-0.5-0.40.4-0.40.40.41.2-0.70.40.8
Delay disc. indifference point, 24s delay0.00.00.0-0.00.1-0.10.1-0.1-0.10.10.00.10.0
Delay disc. indifference point, 4s delay0.30.31.0-0.3-0.30.3-0.30.30.3-0.11.0-0.9-0.9
Delay disc. indifference point, 8s delay0.50.81.0-1.0-1.01.0-1.01.01.01.00.8-0.7-0.7
Indifference point function ln k0.51.62.1-1.5-1.51.5-1.51.51.51.30.6-1.0-0.6
Indifference point function log k0.51.62.1-1.5-1.51.5-1.51.51.51.30.6-1.0-0.6
Patch foraging total patch changes 0 sec0.51.42.8-1.0-0.90.9-0.90.90.90.81.7-1.6-1.5
Patch foraging total patch changes 12 sec0.81.12.80.70.7-0.70.7-0.7-0.7-1.41.4-0.9-1.7
Patch foraging total patch changes 18 sec0.81.83.91.51.5-1.51.5-1.5-1.5-2.00.6-0.4-0.9
Patch foraging total patch changes 24 sec0.31.21.81.01.0-1.01.0-1.0-1.0-1.31.2-0.6-1.3
Patch foraging total patch changes 6 sec0.10.20.50.40.4-0.40.4-0.4-0.4-0.50.7-0.4-0.7
Patch foraging time to switch 0 sec0.00.10.30.00.0-0.00.0-0.0-0.0-0.20.4-0.3-0.5
Patch foraging water rate 0 sec0.10.20.60.40.4-0.40.4-0.4-0.4-0.1-0.50.60.8
Patch foraging water rate 12 sec0.20.81.00.90.9-0.90.9-0.9-0.9-0.7-1.00.81.0
Patch foraging water rate 18 sec1.94.27.51.81.8-1.81.8-1.8-1.8-1.0-2.62.72.6
Patch foraging water rate 24 sec0.10.10.50.10.1-0.10.1-0.1-0.1-0.0-0.50.50.7
Patch foraging water rate 6 sec3.04.56.02.42.4-2.42.4-2.4-2.4-2.2-1.31.21.0
Seeking ratio, delayed vs. immediate footshock3.95.57.0-2.6-2.72.7-2.72.72.72.31.7-1.9-1.3
Distance traveled before self-admin1.22.64.3-1.9-1.91.9-1.91.91.92.1-0.0-0.20.4
Distance traveled after self-admin0.61.03.5-0.3-0.30.3-0.30.30.31.0-1.71.51.9
Extensor digitorum longus weight0.31.24.40.20.2-0.20.2-0.2-0.20.5-2.01.82.1
Bone: elastic displacement0.10.10.3-0.1-0.10.1-0.10.10.1-0.20.5-0.4-0.4
Bone: elastic work0.00.00.10.10.1-0.10.1-0.1-0.10.0-0.20.30.4
Bone: endosteal estimation0.00.10.1-0.2-0.30.3-0.30.30.3-0.00.3-0.3-0.3
Bone: endosteal perimeter0.20.51.4-0.4-0.40.4-0.40.40.4-0.11.1-1.1-1.2
Epididymis fat weight0.20.81.1-1.0-0.90.9-0.90.90.90.90.9-0.5-0.7
Delta time in closed arm before/after self-admin0.30.30.4-0.6-0.60.6-0.60.60.60.60.4-0.5-0.3
Delta time in open arm before/after self-admin0.60.71.11.01.0-1.01.0-1.0-1.0-1.0-0.40.40.2
Diff in mean of infusions in LGA sessions0.61.13.6-0.2-0.20.2-0.20.20.2-0.81.8-1.8-1.9
Delay discount exponential model param0.10.20.40.40.4-0.40.4-0.4-0.4-0.6-0.40.40.2
Extinction: sum of active levers before priming2.53.85.3-2.3-2.22.2-2.22.22.22.11.0-1.4-0.6
Active lever presses in extinction session 60.20.20.6-0.3-0.30.3-0.30.30.30.3-0.70.40.8
Bone: final force1.72.85.01.61.6-1.61.6-1.6-1.6-0.8-2.02.21.9
Bone: final moment1.11.93.81.21.2-1.21.2-1.2-1.2-0.5-1.71.91.7
Food consumed during 24 hour testing period2.65.29.62.62.6-2.62.6-2.6-2.6-3.1-0.61.10.2
Glucose0.81.21.81.31.4-1.41.4-1.4-1.4-0.5-0.60.70.4
Heart weight0.91.52.8-1.2-1.11.1-1.11.11.10.91.3-1.7-1.2
Delay discount hyperbolic model param0.10.20.30.40.4-0.40.4-0.4-0.4-0.5-0.40.40.3
Intermittent access intake day 1-15 change0.95.17.52.62.6-2.62.6-2.6-2.6-2.7-0.51.3-0.0
Intermittent access intake escalation0.73.95.62.32.3-2.32.3-2.3-2.3-2.4-0.51.10.1
Intermittent access intake escalation 21.83.05.12.02.0-2.02.0-2.0-2.0-2.30.50.3-0.8
Intermitt. access day 1 inactive lever presses0.00.31.4-0.3-0.20.2-0.20.20.2-0.10.6-0.8-1.2
Intermitt. access day 15 inactive lever presses0.31.62.9-1.1-1.11.1-1.11.11.10.61.7-1.6-1.7
Intermitt. access escalation Index0.10.20.3-0.4-0.40.4-0.40.40.40.50.4-0.3-0.0
Intermittent access day 1 total infusions0.61.82.7-1.6-1.51.5-1.51.51.51.60.6-0.8-0.4
Intermittent access day 15 total infusions0.00.00.0-0.0-0.00.0-0.00.00.00.1-0.10.20.1
Intermittent access terminal intake (last 3 days)0.10.20.6-0.3-0.30.3-0.30.30.30.20.8-0.5-0.7
Intermittent access total infusions0.00.00.1-0.1-0.10.1-0.10.10.10.20.3-0.1-0.2
Intermittent access day 1 locomotion0.20.41.3-0.2-0.20.2-0.20.20.20.6-1.10.71.1
Intermittent access day 15 total locomotion0.10.51.8-0.3-0.30.3-0.30.30.30.7-1.21.11.3
Intermittent access total locomotion0.20.30.8-0.1-0.20.2-0.20.20.20.5-0.80.90.9
Intermittent access standard deviation0.31.32.11.31.3-1.31.3-1.3-1.3-1.40.40.3-0.4
Left kidney weight0.43.23.81.91.9-1.91.9-1.9-1.9-1.6-1.61.91.2
Right kidney weight0.10.71.01.01.0-1.01.0-1.0-1.0-0.7-0.51.00.1
Cocaine induced anxiety0.82.26.1-1.0-1.01.0-1.01.01.00.32.5-2.1-2.5
Post-drug Anxiety1.01.22.8-0.8-0.80.8-0.80.80.80.31.7-1.5-1.6
Baseline Anxiety0.50.82.50.60.6-0.60.6-0.6-0.6-0.1-1.61.31.6
Tail length0.84.25.52.32.3-2.32.3-2.3-2.3-1.9-1.41.50.9
Length with tail0.20.91.61.01.0-1.01.0-1.0-1.0-0.7-0.81.30.6
Length without tail0.10.40.6-0.8-0.80.8-0.80.80.80.80.10.1-0.1
Times rat made contact with spout0.20.30.80.30.3-0.30.3-0.3-0.3-0.0-0.90.80.9
Lifetime Intake0.10.10.50.00.0-0.00.0-0.0-0.0-0.10.7-0.3-0.7
Liver weight, left0.10.20.30.50.5-0.50.5-0.5-0.5-0.50.3-0.0-0.6
Liver weight, right0.10.10.80.10.0-0.00.0-0.0-0.00.3-0.60.90.4
Locomotor activity0.10.10.6-0.1-0.00.0-0.00.00.00.8-0.60.40.6
Locomotor testing distance0.00.10.3-0.1-0.10.1-0.10.10.10.5-0.1-0.3-0.3
Locomotor testing rearing0.30.92.10.80.8-0.80.8-0.8-0.8-1.31.0-0.7-1.4
Locomotion in novel chamber0.30.40.5-0.7-0.70.7-0.70.70.70.70.6-0.3-0.6
Locomotion in novel chamber post-restriction0.30.81.90.80.8-0.80.8-0.8-0.8-0.7-1.41.10.9
Fecal boli incidents, locomotor time 10.30.82.10.90.9-0.90.9-0.9-0.9-1.40.5-0.3-0.9
Change in fecal boli incidents, locomotor task0.20.20.7-0.0-0.00.0-0.00.00.0-0.20.8-0.7-0.7
Time >=10cm from walls, locomotor time 10.50.61.50.70.6-0.60.6-0.6-0.60.2-1.11.21.1
Bouts of movement, locomotor time 10.30.41.40.80.7-0.70.7-0.7-0.7-1.2-0.1-0.1-0.1
Total resting periods, locomotor time 10.20.20.90.40.3-0.30.3-0.3-0.3-1.00.1-0.4-0.3
Rest time, locomotor task time 10.20.30.50.60.5-0.50.5-0.5-0.5-0.7-0.50.20.3
Distance moved, locomotor task time 10.20.60.7-0.9-0.90.9-0.90.90.90.70.6-0.7-0.4
Vertical activity count, locomotor time 10.10.50.70.80.8-0.80.8-0.8-0.8-0.6-0.20.5-0.0
Time >=10cm from walls, locomotor time 20.30.71.4-0.7-0.70.7-0.70.70.71.1-0.90.91.2
Bouts of movement, locomotor time 20.00.10.1-0.4-0.40.4-0.40.40.40.1-0.1-0.30.1
Total resting periods, locomotor time 20.00.10.3-0.1-0.10.1-0.10.10.1-0.30.2-0.6-0.3
Rest time, locomotor task time 20.30.41.40.40.4-0.40.4-0.4-0.4-1.00.7-1.2-0.9
Distance moved, locomotor task time 21.41.93.6-1.5-1.61.6-1.61.61.61.9-0.10.30.5
Vertical activity count, locomotor time 20.10.20.60.60.5-0.50.5-0.5-0.5-0.2-0.10.7-0.1
Light reinforcement 14.620.627.75.35.2-5.25.2-5.2-5.2-5.2-2.12.91.0
Light reinforcement 25.311.915.84.04.0-4.04.0-4.0-4.0-3.8-1.92.41.3
Bone: marrow area0.00.10.1-0.3-0.30.3-0.30.30.30.00.3-0.4-0.3
Bone: maximum diameter0.10.30.3-0.6-0.60.6-0.60.60.60.40.6-0.5-0.5
Bone: maximum force0.30.61.20.60.6-0.60.6-0.6-0.6-0.4-1.01.01.1
Bone: maximum moment0.10.20.70.30.3-0.30.3-0.3-0.3-0.2-0.70.70.9
Mean time between licks in bursts0.10.31.3-0.3-0.20.2-0.20.20.20.31.1-0.6-1.1
Mean num. licks in bursts0.10.30.9-0.4-0.40.4-0.40.40.40.8-0.80.51.0
Cd content in liver4.34.76.0-2.2-2.32.3-2.32.32.30.62.4-2.4-2.1
Co content in liver1.72.02.5-1.6-1.61.6-1.61.61.61.01.2-1.2-1.1
Cu content in liver0.10.10.3-0.1-0.10.1-0.10.10.10.3-0.40.50.3
Fe content in liver3.94.812.51.51.5-1.51.5-1.5-1.5-0.3-3.53.33.4
K content in liver1.11.12.1-1.0-1.01.0-1.01.01.01.5-0.90.81.1
Mg content in liver0.50.61.4-0.8-0.80.8-0.80.80.81.2-0.10.10.1
Mn content in liver1.31.52.7-1.1-1.11.1-1.11.11.10.61.6-1.7-1.3
Na content in liver0.91.03.50.10.1-0.10.1-0.1-0.10.6-1.91.71.9
Rb content in liver0.70.81.11.01.0-1.01.0-1.0-1.0-0.6-0.70.80.4
Se content in liver2.93.57.21.61.5-1.51.5-1.5-1.5-0.6-2.72.72.4
Sr content in liver0.50.40.6-0.7-0.80.8-0.80.80.80.60.3-0.2-0.2
Zn content in liver1.82.12.8-1.6-1.71.7-1.71.71.71.60.7-0.9-0.4
Bone: minimum diameter0.81.51.71.31.3-1.31.3-1.3-1.3-1.2-1.01.10.9
Time in familiar zone, hab. session 10.30.30.70.60.6-0.60.6-0.6-0.6-0.8-0.20.60.0
Time in novel zone, hab. session 10.40.51.0-0.7-0.60.6-0.60.60.61.0-0.6-0.10.8
Total zone transitions, hab. session 10.20.20.5-0.4-0.40.4-0.40.40.40.20.7-0.7-0.6
Total locomotion distance, hab. session 10.40.61.1-0.8-0.80.8-0.80.80.80.40.9-1.1-0.6
Locomotion velocity, hab. session 10.40.51.1-0.7-0.70.7-0.70.70.70.41.0-1.1-0.7
Time in familiar zone, hab. session 21.51.72.91.41.5-1.51.5-1.5-1.5-1.70.6-0.3-0.8
Time in novel zone, hab. session 23.23.55.1-2.2-2.22.2-2.22.22.22.2-0.2-0.40.4
Total zone transitions, hab. session 20.10.20.70.20.2-0.20.2-0.2-0.2-0.40.6-0.6-0.8
Total locomotion distance, hab. session 20.10.10.5-0.2-0.10.1-0.10.10.1-0.10.6-0.7-0.7
Locomotion velocity, hab. session 20.00.00.10.10.1-0.10.1-0.1-0.1-0.30.2-0.3-0.3
Novel to familiar place preference ratio1.01.42.0-1.4-1.41.4-1.41.41.41.20.2-0.40.3
Novelty place preference0.81.11.6-1.3-1.31.3-1.31.31.31.00.0-0.40.4
Time in novel zone, NPP test0.91.11.4-1.2-1.21.2-1.21.21.21.2-0.40.10.8
Total zone transitions, NPP test0.10.20.80.20.2-0.20.2-0.2-0.2-0.00.6-0.3-0.9
Total locomotion distance, NPP test0.00.00.2-0.2-0.10.1-0.10.10.10.5-0.1-0.00.1
Locomotion velocity, NPP test0.00.00.20.00.1-0.10.1-0.1-0.10.00.3-0.3-0.5
Intraocular pressure3.96.47.9-2.7-2.82.8-2.82.82.82.12.1-2.4-1.5
Delta distance traveled before/after self-admin2.42.73.31.71.7-1.71.7-1.7-1.7-1.2-1.61.81.4
Delta ambulatory time before/after self-admin2.34.05.02.22.2-2.22.2-2.2-2.2-1.8-1.51.91.1
Parametrial fat weight0.30.73.00.00.0-0.00.0-0.0-0.0-0.51.7-1.1-1.7
Pavlov. Cond. lever latency0.20.20.8-0.1-0.10.1-0.10.10.1-0.20.8-0.8-0.9
Pavlov. Cond. magazine entry latency0.10.10.3-0.3-0.30.3-0.30.30.30.3-0.50.30.5
Pavlov. Cond. change in total contacts1.31.43.11.00.9-0.90.9-0.9-0.9-0.5-1.81.61.6
Pavlov. Cond. index score0.20.20.3-0.4-0.50.5-0.50.50.50.5-0.50.40.5
Pavlov. Cond. latency score0.10.10.2-0.4-0.40.4-0.40.40.40.3-0.10.10.2
Pavlov. Cond. lever contacts0.20.20.80.0-0.00.0-0.00.00.00.4-0.90.80.9
Pavlov. Cond. magazine entry number0.40.51.30.30.3-0.30.3-0.3-0.3-0.81.1-1.0-1.1
Pavlov. Cond. intertrial magazine entries0.10.10.30.00.0-0.00.0-0.0-0.00.20.5-0.4-0.5
Pavlov. Cond. lever-magazine prob. diff.0.30.40.5-0.6-0.60.6-0.60.60.60.7-0.50.40.6
Pavlov. Cond. response bias0.60.82.6-0.0-0.00.0-0.00.00.00.8-1.61.41.6
Pavlov. Cond. lever latency0.30.40.5-0.7-0.70.7-0.70.70.70.6-0.1-0.30.2
Pavlov. Cond. magazine entry latency0.10.10.30.20.2-0.20.2-0.2-0.2-0.40.5-0.1-0.5
Pavlov. Cond. change in total contacts0.00.00.20.10.1-0.10.1-0.1-0.10.1-0.10.40.2
Pavlov. Cond. index score0.00.00.10.20.2-0.20.2-0.2-0.2-0.10.10.3-0.1
Pavlov. Cond. latency score0.00.00.10.20.2-0.20.2-0.2-0.2-0.20.10.3-0.0
Pavlov. Cond. lever contacts0.50.81.11.01.1-1.11.1-1.1-1.1-0.8-0.10.6-0.1
Pavlov. Cond. magazine entry number0.00.00.00.00.0-0.00.0-0.0-0.00.0-0.2-0.10.2
Pavlov. Cond. intertrial magazine entries0.40.81.21.11.1-1.11.1-1.1-1.1-1.0-0.30.30.0
Pavlov. Cond. lever-magazine prob. diff.0.00.00.10.20.2-0.20.2-0.2-0.2-0.10.10.3-0.0
Pavlov. Cond. response bias0.20.30.40.70.7-0.70.7-0.7-0.7-0.3-0.10.5-0.0
Time in closed arm before self-admin2.44.15.12.32.2-2.22.2-2.2-2.2-1.6-1.82.11.5
Time in closed arm after self-admin1.31.51.71.31.2-1.21.2-1.2-1.2-0.9-1.31.31.1
Time in open arm before self-admin1.92.32.7-1.6-1.61.6-1.61.61.61.11.6-1.4-1.3
Time in open arm after self-admin0.70.81.1-1.1-1.01.0-1.01.01.01.10.5-0.6-0.3
Bone: periosteal estimation0.10.10.20.40.4-0.40.4-0.4-0.4-0.5-0.10.10.1
Bone: periosteal perimeter0.10.20.8-0.1-0.10.1-0.10.10.1-0.00.7-0.9-0.9
Bone: post-yield work0.00.10.3-0.2-0.10.1-0.10.10.1-0.20.3-0.6-0.1
Progressive ratio test 1 active lever presses0.10.20.5-0.1-0.10.1-0.10.10.10.3-0.70.70.6
Progressive ratio test 1 breakpoint0.10.20.6-0.1-0.10.1-0.10.10.10.3-0.80.80.7
Progressive ratio test 1 inactive lever presses0.00.10.2-0.4-0.30.3-0.30.30.30.30.2-0.0-0.4
Progressive ratio test 2 active lever presses0.10.10.1-0.3-0.30.3-0.30.30.30.3-0.00.20.2
Progressive ratio test 2 breakpoint0.10.10.2-0.4-0.40.4-0.40.40.40.4-0.00.10.2
Progressive ratio test 2 inactive lever presses0.51.51.9-1.3-1.21.2-1.21.21.21.01.4-1.2-1.1
Incentive Sensitization - Responses0.10.20.8-0.2-0.30.3-0.30.30.3-0.10.9-0.6-0.6
Incentive Sensitization - Breakpoint0.10.20.7-0.2-0.20.2-0.20.20.2-0.20.9-0.6-0.6
Sum of active levers in priming session hrs 5-60.30.30.6-0.5-0.50.5-0.50.50.50.10.6-0.8-0.5
Progressive ratio0.10.30.40.60.6-0.60.6-0.6-0.6-0.5-0.00.00.4
Food seeking constrained by brief footshock2.02.53.81.81.9-1.91.9-1.9-1.9-2.0-0.20.60.3
Seeking ratio, punishment vs. effort0.51.01.31.11.1-1.11.1-1.1-1.1-1.1-0.71.00.2
Retroperitoneal fat weight0.62.98.6-1.1-1.01.0-1.01.01.00.22.8-2.4-2.9
Reaction time number correct0.20.61.3-0.8-0.80.8-0.80.80.81.10.3-0.40.1
Reaction time mean minus median0.21.33.0-1.2-1.21.2-1.21.21.21.7-0.80.50.8
Reaction time mean minus median AUC0.21.52.6-1.4-1.41.4-1.41.41.41.6-0.50.20.5
Reaction time num false alarms3.66.16.7-2.6-2.62.6-2.62.62.62.02.5-2.4-2.3
Reaction time num false alarms AUC2.25.15.6-2.4-2.32.3-2.32.32.31.92.3-2.3-2.1
Reaction time trials correct on left0.20.61.3-0.8-0.80.8-0.80.80.81.10.3-0.40.1
Reaction time trials on left0.20.71.5-0.9-0.90.9-0.90.90.91.20.3-0.50.1
Reaction time mean2.14.66.6-2.5-2.62.6-2.62.62.62.4-0.2-0.00.5
Reaction time mean AUC1.94.56.6-2.5-2.62.6-2.62.62.62.4-0.1-0.10.4
Median of all reaction times2.74.26.2-2.4-2.52.5-2.52.52.52.2-0.1-0.10.3
Reaction time omissions1.52.44.0-1.8-1.81.8-1.81.81.82.00.8-0.8-0.5
Reaction time false alarm rate1.82.43.6-1.5-1.51.5-1.51.51.51.01.8-1.7-1.9
Reaction time premature initiation rate2.74.18.62.32.3-2.32.3-2.3-2.3-2.90.9-0.2-1.1
Reaction time premature initiations0.72.04.01.51.5-1.51.5-1.5-1.5-2.01.1-0.5-1.1
Std. dev. reaction times0.51.83.2-1.5-1.51.5-1.51.51.51.8-0.40.20.5
Reaction time trials completed0.20.71.5-0.9-0.90.9-0.90.90.91.20.3-0.50.1
Reaction time trials AUC0.20.81.6-1.0-1.01.0-1.01.01.01.30.4-0.50.1
Run reversals in cocaine runway, females0.20.20.7-0.5-0.50.5-0.50.50.50.8-0.20.10.3
Run reversals in cocaine runway, males0.20.20.3-0.5-0.50.5-0.50.50.50.5-0.50.10.5
Latency to leave start box in cocaine runway0.40.50.7-0.8-0.80.8-0.80.80.80.30.4-0.8-0.6
Latency to leave start box in cocaine runway, F0.70.91.2-1.1-1.11.1-1.11.11.11.0-0.6-0.20.6
Latency to leave start box in cocaine runway, M1.00.93.30.20.2-0.20.2-0.2-0.2-1.31.6-1.2-1.8
Std. dev. time between licks in bursts0.10.20.30.50.5-0.50.5-0.5-0.5-0.50.10.2-0.3
Total sessions with >9 infusions0.00.00.1-0.1-0.10.1-0.10.10.10.2-0.30.20.1
Short access day 1 total inactive lever presses0.00.10.40.20.2-0.20.2-0.2-0.2-0.0-0.40.60.1
Short access day 10 total inactive lever presses0.00.30.60.50.6-0.60.6-0.6-0.6-0.80.5-0.1-0.7
Short access day 1 total infusions0.30.60.9-0.9-0.90.9-0.90.90.90.90.4-0.5-0.4
Short access day 10 total infusions0.10.10.5-0.00.0-0.00.0-0.0-0.0-0.20.5-0.4-0.7
Short access total infusions0.10.10.6-0.2-0.20.2-0.20.20.20.10.5-0.4-0.7
Short access day 1 locomotion1.21.92.7-1.6-1.61.6-1.61.61.61.60.6-0.8-0.4
Short access day 10 total locomotion0.00.10.1-0.3-0.30.3-0.30.30.30.4-0.10.00.0
Short access total locomotion0.30.50.6-0.8-0.80.8-0.80.80.80.70.4-0.5-0.3
One hour access (0.3 mA shock)1.21.44.7-0.6-0.60.6-0.60.60.6-0.02.2-1.9-2.0
Compulsive drug intake0.30.41.7-0.1-0.20.2-0.20.20.2-0.30.9-1.3-1.1
One hour access (shock baseline)0.20.51.5-0.5-0.40.4-0.40.40.40.21.2-1.0-1.0
Social response proportion0.20.30.3-0.6-0.60.6-0.60.60.60.3-0.40.50.6
Social responses0.70.92.4-0.6-0.60.6-0.60.60.6-0.31.5-1.3-1.6
Social time0.40.70.90.90.8-0.80.8-0.8-0.8-1.0-0.80.70.6
Soleus weight0.10.41.20.20.3-0.30.3-0.3-0.3-0.31.0-1.0-1.1
Bone: stiffness0.30.61.50.50.5-0.50.5-0.5-0.5-0.0-1.21.11.2
Tibialis anterior weight0.41.32.2-1.3-1.31.3-1.31.31.31.5-0.2-0.10.4
Time to tail flick, vehicle, before self-admin0.20.21.0-0.10.0-0.00.0-0.0-0.0-0.30.7-1.0-0.7
Time to tail flick, vehicle, after self-admin0.30.71.60.60.5-0.50.5-0.5-0.5-1.31.0-0.9-1.2
Time to tail flick, test, before self-admin1.11.21.5-1.2-1.21.2-1.21.21.20.90.9-1.1-0.7
Time to tail flick, test, after self-admin1.21.22.31.11.0-1.01.0-1.0-1.0-0.6-1.51.21.4
Delta time to tail flick, vehicle, before/after SA0.20.20.50.50.4-0.40.4-0.4-0.4-0.70.3-0.1-0.4
Delta time to tail flick, test, before/after SA2.53.16.81.41.4-1.41.4-1.4-1.4-0.3-2.62.52.5
Tibia length0.51.44.7-0.00.0-0.00.0-0.0-0.01.4-2.01.92.2
Ambulatory time before self-admin1.03.04.7-2.0-2.02.0-2.02.02.02.20.2-0.50.2
Ambulatory time after self-admin0.60.92.90.40.4-0.40.4-0.4-0.40.2-1.71.61.7
Bone: tissue strength0.10.10.2-0.3-0.30.3-0.30.30.30.1-0.20.40.4
Total heroin consumption0.40.51.0-0.7-0.70.7-0.70.70.70.21.0-0.8-0.9
Bone: trabecular number1.52.73.41.81.9-1.91.9-1.9-1.9-1.5-1.40.91.3
Bone: trabecular spacing1.72.53.4-1.7-1.91.9-1.91.91.91.21.3-0.9-1.1
Bone: trabecular thickness3.65.05.92.22.3-2.32.3-2.3-2.3-1.4-2.42.22.3
Bone: trabecular tissue density0.40.81.1-1.0-1.11.1-1.11.11.11.00.2-0.2-0.0
Water consumed over 24 hours1.12.13.01.61.6-1.61.6-1.6-1.6-1.7-0.81.20.6
Number of responses in last shaping day1.62.03.1-1.4-1.41.4-1.41.41.41.11.8-1.6-1.5