Hub : Genes

Adamts20

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL gene expression Adamts20 0.62 0.22 1.9e-03 0.08 0.06 0.14 0.09 5.2e-03 1.5e-02 3.2e-04 3.6e-03
2 LHb isoform ratio NM_001421315.1 0.58 0.28 1.8e-05 0.13 0.13 0.14 0.14 5.4e-04 5.5e-04 3.2e-04 4.1e-04
3 LHb isoform ratio XM_039080336.1 0.54 0.31 1.8e-04 0.1 0.1 0.11 0.11 1.9e-03 2.7e-03 1.2e-03 1.6e-03
4 NAcc gene expression Adamts20 0.04 0.03 1.4e-04 0.03 0.02 0.01 0.02 2.9e-05 3.7e-04 1.0e-02 1.6e-04
5 Brain isoform ratio NM_001421315.1 0.03 0.03 6.6e-03 0.01 0.02 0.02 0.01 2.2e-02 7.3e-03 1.0e-02 2.2e-02
6 NAcc intron excision ratio chr7_127277490_127280787 0.04 0.03 2.0e-05 0.02 0.03 0.02 0.02 3.4e-04 1.7e-05 1.1e-04 1.1e-04
7 Brain intron excision ratio chr7_127277490_127280787 0.08 0.06 8.9e-08 0.06 0.08 0.07 0.07 1.4e-06 9.7e-08 1.9e-07 2.1e-07
8 OFC gene expression Adamts20 0.16 0.14 5.8e-03 0.04 0.04 -0.01 0.03 3.9e-02 3.3e-02 6.6e-01 6.8e-02
9 PL gene expression Adamts20 0.1 0.09 1.5e-09 0.09 0.09 0.09 0.09 4.2e-10 7.7e-10 7.9e-10 4.8e-10
10 NAcc isoform ratio XM_039080336.1 0.04 0.03 3.4e-07 0.05 0.04 0.04 0.04 4.2e-08 2.5e-07 1.1e-06 3.0e-07
11 PL alternative TSS XM_039080336.1 0.02 0.02 9.4e-04 0.03 0.02 0.02 0.03 4.3e-04 2.0e-03 1.8e-03 8.7e-04
12 pVTA gene expression Adamts20 0.11 0.09 5.9e-07 0.09 0.08 0.06 0.08 9.7e-08 7.6e-07 1.1e-05 2.6e-07
13 pVTA isoform ratio NM_001421315.1 0.03 0.02 2.4e-03 0.01 0.03 0.02 0.02 2.4e-02 1.6e-03 8.6e-03 1.7e-02
14 pVTA isoform ratio XM_039080336.1 0.03 0.02 2.8e-03 0 0.02 0.01 0.01 1.6e-01 9.5e-03 2.9e-02 7.9e-02
15 Brain gene expression Adamts20 0.08 0.06 3.1e-07 0.07 0.07 0.06 0.07 5.7e-07 5.1e-07 1.5e-06 4.6e-07
16 PL isoform ratio XM_039080336.1 0.06 0.04 1.0e-07 0.07 0.07 0.06 0.07 9.5e-08 2.2e-08 3.4e-07 9.5e-08
17 PL isoform ratio NM_001421315.1 0.02 0.01 7.2e-03 0.02 0.02 0.01 0.01 5.6e-03 6.8e-03 2.3e-02 1.7e-02
18 NAcc isoform ratio NM_001421315.1 0.03 0.02 9.6e-07 0.05 0.04 0.04 0.04 3.4e-08 2.3e-07 3.3e-07 4.2e-07
19 pVTA intron excision ratio chr7_127277490_127280787 0.11 0.08 2.6e-05 0.02 0.05 0.05 0.04 5.5e-03 5.8e-05 1.3e-04 2.6e-04
20 BLA gene expression Adamts20 0.1 0.07 7.5e-05 0.06 0.05 0.03 0.05 7.3e-04 7.5e-04 1.2e-02 1.3e-03
21 Brain isoform ratio XM_039080336.1 0.09 0.06 8.9e-10 0.08 0.09 0.1 0.09 6.0e-08 1.7e-08 3.7e-09 1.4e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density0.50.92.60.5-0.50.80.91.01.20.9-1.00.91.01.01.01.0-1.0-0.9-0.9-1.0-0.80.90.8-1.6
Area under the delay curve0.20.31.1-0.6-0.30.50.00.40.40.5-0.50.20.50.50.80.6-0.6-0.6-0.7-0.7-1.00.61.00.1
BMI with tail0.20.81.71.1-1.11.11.20.90.71.0-0.91.30.60.60.60.9-0.9-0.9-0.8-0.6-0.21.00.4-1.3
BMI without tail0.10.61.40.9-1.11.20.90.70.40.9-0.70.90.40.40.50.7-0.7-0.6-0.6-0.4-0.40.90.5-1.2
Body weight1.25.47.91.5-2.42.82.72.52.22.6-2.42.82.22.22.22.5-2.5-2.4-2.4-2.2-2.02.62.2-1.0
Weight adjusted by age0.30.81.80.1-0.90.80.40.90.91.0-0.90.30.80.81.21.0-1.0-0.9-1.1-1.1-1.30.91.30.0
Bone surface1.93.74.61.6-1.72.02.12.12.12.0-2.02.12.02.01.92.0-2.0-2.0-1.9-1.9-1.81.91.8-1.4
Bone volume0.91.82.61.0-0.91.21.41.41.61.3-1.41.41.41.41.41.4-1.4-1.3-1.3-1.4-1.11.21.2-1.6
Breakpoint value in progressive ratio session0.71.32.5-0.40.00.30.91.21.60.9-1.31.11.41.41.31.2-1.2-1.2-1.3-1.3-1.11.01.1-1.3
Number of licking bursts0.20.71.2-0.10.7-0.8-0.7-0.8-0.7-0.90.8-0.8-0.8-0.8-0.9-0.90.90.80.90.91.1-0.9-0.9-0.2
Context. condit. distance diff. score1.21.42.30.60.7-0.7-0.6-1.2-1.3-1.21.3-0.7-1.3-1.3-1.5-1.41.41.21.41.51.4-1.4-1.50.6
Locomotion velocity, session 10.40.40.80.50.1-0.0-0.6-0.5-0.8-0.40.6-0.7-0.7-0.7-0.8-0.70.70.80.70.80.9-0.6-0.80.6
Locomotion distance, session 10.30.30.7-0.5-0.20.20.30.50.70.5-0.60.20.70.70.70.6-0.6-0.5-0.7-0.6-0.80.60.8-0.9
Locomotion velocity, session 20.10.10.60.2-0.40.5-0.00.40.30.4-0.4-0.00.30.30.30.4-0.4-0.2-0.3-0.3-0.20.30.4-0.8
Locomotion distance, session 20.10.10.60.1-0.10.1-0.30.40.60.2-0.4-0.30.50.50.50.3-0.3-0.1-0.4-0.4-0.20.10.4-0.8
Locomotion velocity, session 30.40.53.11.8-0.20.1-0.2-0.3-0.5-0.40.4-0.3-0.6-0.6-0.8-0.70.70.60.70.70.7-0.8-1.00.0
Locomotion distance, session 32.93.34.7-0.41.7-1.8-1.6-1.8-1.7-1.91.8-1.6-1.8-1.8-2.0-2.02.01.92.02.02.0-2.1-2.21.2
Stereotopy head waving bouts, day 30.80.91.70.9-1.21.01.00.90.91.0-0.91.10.80.80.90.9-0.9-1.0-0.9-0.9-1.31.01.0-0.4
Stereotopy head waving duration, day 30.50.62.61.6-1.51.20.60.70.40.8-0.60.60.40.40.40.6-0.6-0.6-0.6-0.5-0.70.70.5-0.5
Locomotion velocity, session 72.02.22.91.6-1.51.51.61.61.61.5-1.51.71.51.51.51.4-1.4-1.6-1.4-1.4-1.41.21.3-0.4
Locomotion distance, session 70.30.42.0-0.30.8-0.7-0.5-0.5-0.4-0.70.5-0.4-0.3-0.3-0.5-0.60.60.50.60.60.7-0.8-0.71.4
Stereotopy head waving bouts, day 70.80.93.71.9-1.51.20.90.90.70.9-0.80.80.80.80.60.7-0.8-0.7-0.7-0.6-0.60.80.5-1.2
Stereotopy head waving duration, day 71.21.53.21.7-1.71.51.21.21.01.3-1.11.11.11.11.01.1-1.1-1.1-1.1-1.0-1.11.21.0-1.8
Locomotion velocity, session 81.31.52.31.2-1.31.51.51.31.31.3-1.31.41.41.41.21.2-1.2-1.2-1.1-1.1-0.81.21.1-0.7
Locomotion distance, session 81.01.52.40.30.9-0.9-1.0-1.2-1.2-1.21.2-1.2-1.1-1.1-1.5-1.41.41.41.41.51.5-1.5-1.50.7
Degree of sensitization distance1.81.92.60.4-1.31.41.31.41.41.5-1.41.31.51.51.51.5-1.5-1.4-1.5-1.5-1.51.51.6-0.2
Degree of sensitization stereotypy0.40.42.91.7-1.00.80.60.50.40.6-0.50.50.50.50.20.4-0.4-0.4-0.4-0.3-0.20.30.1-1.0
Conditioned locomotion0.10.11.0-1.0-0.10.2-0.10.1-0.10.2-0.10.0-0.1-0.10.20.2-0.3-0.1-0.2-0.3-0.30.50.5-0.2
Cocaine response after cond. corrected0.30.51.0-0.40.10.10.40.70.90.6-0.80.40.90.90.90.8-0.8-0.7-0.8-1.0-1.00.60.8-0.1
Cocaine response after cond. not corrected0.10.20.6-0.80.5-0.30.00.30.50.2-0.30.00.50.50.40.4-0.4-0.3-0.4-0.5-0.50.20.30.0
Cocaine response before conditioning1.82.13.3-0.51.1-1.2-1.2-1.5-1.6-1.51.6-1.2-1.5-1.5-1.7-1.61.61.61.61.81.8-1.5-1.70.7
Saline control response1.92.65.8-2.42.2-2.0-1.5-1.7-1.5-1.71.7-1.5-1.6-1.6-1.4-1.51.51.41.51.41.3-1.4-1.20.8
Bone: connectivity density2.74.35.51.0-1.61.91.92.22.42.2-2.32.02.32.32.22.3-2.3-2.2-2.3-2.3-2.02.22.1-1.5
Bone: cortical apparent density1.42.23.60.7-0.90.81.71.61.91.4-1.61.71.71.71.81.6-1.6-1.7-1.6-1.7-1.31.41.4-0.8
Bone: cortical area0.40.62.11.00.1-0.1-0.4-0.5-0.7-0.40.6-0.4-0.8-0.8-0.8-0.70.70.70.70.81.2-0.7-1.11.4
Bone: cortical porosity0.30.31.3-0.30.3-0.5-0.4-0.5-0.7-0.40.5-0.2-0.7-0.7-0.6-0.50.50.40.60.70.4-0.4-0.4-1.1
Bone: cortical porosity0.10.22.40.7-0.30.20.10.0-0.10.10.00.2-0.2-0.2-0.2-0.10.1-0.00.10.20.1-0.0-0.2-1.6
Bone: cortical thickness1.62.64.10.21.2-1.2-1.7-1.5-1.7-1.51.6-1.7-1.7-1.7-1.7-1.71.71.81.71.72.0-1.7-2.01.2
Bone: cortical thickness2.73.34.70.41.2-1.3-2.0-1.8-2.0-1.71.9-2.0-2.1-2.1-1.9-2.02.01.92.01.92.2-2.0-2.10.4
Bone: cortical tissue density1.52.33.70.7-0.90.91.81.61.91.4-1.71.71.71.71.81.6-1.6-1.7-1.6-1.8-1.31.41.4-0.9
Condit. Reinf. active minus inactive responses4.04.58.73.0-2.42.42.32.32.22.1-2.22.12.02.02.12.0-2.0-2.1-1.9-2.1-1.71.81.6-2.0
Condit. Reinf. active-inactive response ratio3.94.29.13.0-2.72.62.32.11.92.1-2.02.01.81.81.81.9-1.9-1.9-1.8-1.8-1.61.81.6-1.8
Condit. Reinf. active responses4.86.212.63.6-2.72.72.62.72.72.5-2.62.52.42.42.62.3-2.3-2.5-2.3-2.5-1.92.01.8-2.4
Condit. Reinf. inactive responses1.01.35.02.2-0.91.01.11.31.51.0-1.31.21.11.11.30.9-0.9-1.2-1.0-1.2-0.60.50.5-1.0
Incentive salience index mean3.84.97.42.7-2.42.42.32.42.42.3-2.32.02.22.22.32.1-2.1-2.1-2.1-2.2-1.91.91.8-2.1
Condit. Reinf. lever presses4.26.37.42.2-2.42.42.42.72.72.6-2.72.22.72.72.72.5-2.5-2.5-2.6-2.6-2.52.32.4-2.2
Condit. Reinf. active minus inactive responses0.00.00.00.10.0-0.1-0.20.00.1-0.0-0.1-0.10.10.10.10.0-0.0-0.1-0.1-0.1-0.2-0.10.0-0.1
Condit. Reinf. active-inactive response ratio0.20.30.60.50.3-0.5-0.5-0.5-0.5-0.60.5-0.4-0.6-0.6-0.6-0.60.70.50.60.50.6-0.8-0.8-0.2
Condit. Reinf. active responses0.71.01.50.3-0.90.90.81.01.11.0-1.10.81.11.11.11.1-1.1-1.0-1.1-1.1-1.20.91.2-0.4
Condit. Reinf. inactive responses0.91.42.20.1-1.11.11.01.21.21.2-1.20.81.21.21.41.3-1.3-1.1-1.3-1.2-1.41.31.5-0.5
Condit. Reinf. lever presses0.50.71.21.0-1.11.00.80.90.90.9-0.90.60.90.90.80.8-0.8-0.8-0.8-0.8-0.60.70.8-0.1
Condit. Reinf. lever reinforcers received0.40.60.90.5-0.70.70.60.80.90.8-0.90.60.90.90.90.8-0.8-0.8-0.9-0.9-0.90.70.8-0.3
Conditioned reinforcement - actives0.51.82.90.5-1.31.31.01.31.31.4-1.31.21.21.21.61.4-1.4-1.3-1.4-1.4-1.61.51.6-1.7
Conditioned reinforcement - inactives0.20.75.82.4-1.61.50.70.60.10.7-0.50.80.10.10.20.3-0.3-0.4-0.3-0.1-0.30.40.00.1
Conditioned locomotion0.20.30.6-0.30.2-0.3-0.8-0.6-0.7-0.50.6-0.7-0.8-0.8-0.5-0.60.50.60.50.70.2-0.5-0.40.6
Patch foraging indifference point 0 sec0.10.31.9-1.41.0-0.7-0.2-0.5-0.4-0.50.4-0.3-0.4-0.4-0.3-0.30.30.30.40.30.1-0.2-0.10.3
Patch foraging indifference point AUC0.10.21.3-0.30.3-0.3-0.2-0.5-0.6-0.40.5-0.4-0.7-0.7-0.2-0.50.50.30.50.20.4-0.3-0.2-1.2
Delay disc. indifference point, 0s delay1.61.84.9-2.21.6-1.5-1.3-1.6-1.6-1.51.6-1.3-1.3-1.3-0.9-1.31.31.21.41.30.6-1.0-0.70.3
Delay disc. indifference point, 16s delay3.44.96.50.6-1.92.22.12.22.22.2-2.22.12.22.22.42.3-2.3-2.4-2.3-2.5-2.52.42.6-1.8
Delay disc. indifference point, 2s delay0.30.33.7-1.90.8-0.4-0.6-0.5-0.4-0.40.4-0.3-0.3-0.30.0-0.10.10.20.10.1-0.10.10.30.1
Delay disc. indifference point, 24s delay2.03.24.40.0-1.11.11.61.92.11.8-2.01.62.02.02.02.0-2.0-2.0-2.1-2.0-2.11.92.1-0.6
Delay disc. indifference point, 4s delay0.50.62.4-1.60.8-0.5-0.9-0.9-0.9-0.80.9-0.9-0.8-0.8-0.4-0.60.60.70.70.60.5-0.4-0.3-0.1
Delay disc. indifference point, 8s delay0.10.21.4-0.80.3-0.2-0.8-0.2-0.1-0.20.1-0.6-0.1-0.10.2-0.10.10.1-0.0-0.1-0.4-0.10.31.2
Indifference point function ln k0.20.71.00.2-0.91.00.60.90.80.9-0.90.70.90.90.70.9-0.9-0.7-0.9-0.6-0.90.90.80.8
Indifference point function log k0.20.71.00.2-0.91.00.60.90.80.9-0.90.70.90.90.70.9-0.9-0.7-0.9-0.6-0.90.90.80.8
Patch foraging total patch changes 0 sec0.00.10.9-0.90.8-0.5-0.0-0.4-0.3-0.40.3-0.1-0.3-0.3-0.2-0.30.30.10.30.20.2-0.2-0.10.2
Patch foraging total patch changes 12 sec0.20.20.6-0.60.7-0.5-0.1-0.4-0.5-0.40.5-0.3-0.5-0.5-0.3-0.40.40.30.50.30.5-0.4-0.3-0.8
Patch foraging total patch changes 18 sec0.00.10.3-0.10.20.00.40.10.20.1-0.10.30.00.00.40.1-0.1-0.3-0.1-0.4-0.40.10.3-0.5
Patch foraging total patch changes 24 sec0.00.10.50.7-0.10.30.6-0.0-0.1-0.00.10.5-0.3-0.3-0.0-0.20.1-0.20.2-0.10.1-0.1-0.1-0.2
Patch foraging total patch changes 6 sec1.52.64.8-2.02.2-1.9-1.3-1.7-1.6-1.81.7-1.4-1.7-1.7-1.4-1.61.61.51.71.41.6-1.5-1.40.4
Patch foraging time to switch 0 sec0.00.11.0-1.00.8-0.6-0.1-0.20.1-0.30.1-0.10.00.0-0.3-0.10.10.20.10.20.2-0.1-0.20.3
Patch foraging water rate 0 sec0.10.20.50.3-0.20.2-0.6-0.4-0.7-0.20.4-0.5-0.6-0.6-0.3-0.40.40.40.40.40.4-0.3-0.30.7
Patch foraging water rate 12 sec0.20.91.60.00.5-0.5-1.2-0.9-1.1-0.80.9-1.0-1.0-1.0-1.0-1.00.91.00.91.01.2-1.0-1.11.3
Patch foraging water rate 18 sec0.51.12.90.20.3-0.4-1.2-0.9-1.2-0.81.0-1.0-1.1-1.1-1.0-1.01.01.01.00.91.4-1.0-1.11.7
Patch foraging water rate 24 sec0.00.10.50.5-0.20.1-0.2-0.0-0.0-0.10.1-0.10.00.0-0.1-0.10.10.20.10.20.6-0.2-0.30.7
Patch foraging water rate 6 sec0.91.32.1-0.91.4-1.3-1.4-1.2-1.0-1.21.1-1.3-1.0-1.0-1.1-1.11.11.11.11.11.3-1.2-1.30.6
Seeking ratio, delayed vs. immediate footshock2.63.85.2-2.32.0-2.1-1.9-2.1-2.0-2.02.1-2.1-1.8-1.8-2.1-1.91.82.11.92.01.9-1.6-1.8-1.3
Distance traveled before self-admin0.30.72.0-0.81.3-1.4-0.9-0.8-0.5-1.00.8-0.8-0.6-0.6-0.7-0.80.80.80.80.70.8-0.9-0.9-0.4
Distance traveled after self-admin0.10.20.9-0.4-0.20.20.20.40.40.4-0.40.30.70.70.20.5-0.5-0.3-0.4-0.2-0.10.60.3-0.9
Extensor digitorum longus weight0.20.63.9-0.5-0.10.41.00.50.70.4-0.50.80.60.60.70.6-0.7-0.8-0.5-0.7-0.70.80.9-2.0
Bone: elastic displacement6.88.610.1-2.12.8-2.8-3.1-3.1-3.2-3.03.1-3.1-3.0-3.0-3.1-3.03.03.13.03.12.8-2.9-2.92.0
Bone: elastic work3.64.86.1-0.61.7-1.8-2.3-2.3-2.5-2.12.3-2.2-2.4-2.4-2.4-2.32.32.42.32.42.3-2.2-2.41.3
Bone: endosteal estimation0.71.73.51.4-1.91.91.61.31.01.5-1.31.51.11.11.01.3-1.3-1.3-1.2-1.1-1.01.51.2-0.2
Bone: endosteal perimeter0.10.10.40.2-0.60.70.50.30.10.4-0.30.50.10.10.10.3-0.3-0.3-0.3-0.2-0.30.50.40.4
Epididymis fat weight0.21.03.40.5-1.71.80.91.00.41.3-0.90.90.60.60.91.1-1.1-0.8-1.0-0.7-0.71.41.10.4
Delta time in closed arm before/after self-admin0.10.10.5-0.50.4-0.5-0.1-0.20.1-0.30.1-0.00.10.10.0-0.10.1-0.00.1-0.10.0-0.20.00.7
Delta time in open arm before/after self-admin0.20.30.70.00.2-0.1-0.8-0.5-0.6-0.40.5-0.8-0.8-0.8-0.5-0.50.50.60.50.50.5-0.6-0.5-0.1
Diff in mean of infusions in LGA sessions0.30.50.8-0.2-0.20.30.50.70.80.6-0.70.50.80.80.90.8-0.8-0.8-0.8-0.9-0.90.70.8-0.5
Delay discount exponential model param0.20.20.80.70.2-0.40.1-0.3-0.3-0.40.4-0.0-0.3-0.3-0.7-0.50.50.40.50.60.9-0.5-0.8-0.2
Extinction: sum of active levers before priming2.23.36.9-2.61.8-1.7-2.0-1.8-1.9-1.61.8-2.0-1.8-1.8-1.8-1.61.61.81.61.81.7-1.3-1.42.2
Active lever presses in extinction session 60.40.45.3-2.31.3-0.8-0.6-0.10.3-0.2-0.0-0.40.50.50.10.2-0.20.0-0.2-0.10.00.20.2-0.1
Bone: final force2.03.26.42.4-2.52.52.01.91.42.0-1.82.01.51.51.61.7-1.7-1.7-1.6-1.6-1.21.91.5-0.6
Bone: final moment1.62.75.62.3-2.42.41.91.71.31.9-1.61.81.31.31.41.6-1.6-1.5-1.5-1.4-1.01.71.3-0.3
Food consumed during 24 hour testing period0.00.11.31.1-0.20.20.10.10.10.0-0.00.2-0.1-0.10.0-0.10.1-0.00.10.10.2-0.2-0.3-0.6
Glucose0.10.11.41.2-0.40.4-0.20.1-0.10.1-0.1-0.4-0.2-0.20.1-0.10.10.10.0-0.00.3-0.2-0.20.1
Heart weight1.62.65.52.3-1.81.81.81.71.61.7-1.61.91.51.51.51.5-1.5-1.7-1.5-1.6-1.51.31.30.0
Delay discount hyperbolic model param0.20.20.70.70.1-0.30.1-0.2-0.3-0.30.3-0.0-0.3-0.3-0.7-0.40.40.40.50.60.8-0.5-0.8-0.1
Intermittent access intake day 1-15 change0.10.50.90.1-0.80.80.00.70.60.8-0.70.10.80.80.80.8-0.8-0.5-0.8-0.8-1.00.70.9-0.2
Intermittent access intake escalation0.10.40.7-0.0-0.80.7-0.10.50.40.7-0.6-0.00.60.60.70.7-0.7-0.4-0.7-0.6-0.90.70.8-0.1
Intermittent access intake escalation 20.10.10.6-0.80.2-0.2-0.6-0.4-0.5-0.20.3-0.6-0.3-0.3-0.2-0.20.20.40.20.20.1-0.1-0.00.4
Intermitt. access day 1 inactive lever presses0.00.42.21.5-0.70.81.00.60.50.5-0.51.00.50.50.50.4-0.4-0.6-0.3-0.4-0.60.30.30.7
Intermitt. access day 15 inactive lever presses0.94.633.15.8-3.63.32.32.01.32.0-1.72.41.11.11.11.3-1.3-1.7-1.3-1.2-1.21.10.6-1.1
Intermitt. access escalation Index0.31.01.4-0.61.2-1.1-0.8-1.0-0.9-1.11.0-0.8-0.8-0.8-1.2-1.11.11.01.11.11.1-1.1-1.20.5
Intermittent access day 1 total infusions0.10.40.50.7-0.0-0.1-0.7-0.5-0.7-0.50.6-0.6-0.7-0.7-0.7-0.60.60.60.60.70.6-0.6-0.70.1
Intermittent access day 15 total infusions0.10.10.80.8-0.90.7-0.30.2-0.00.4-0.2-0.20.20.20.20.2-0.2-0.0-0.2-0.1-0.50.20.3-0.2
Intermittent access terminal intake (last 3 days)0.10.20.70.8-0.90.8-0.10.30.10.5-0.3-0.00.20.20.30.3-0.3-0.2-0.3-0.2-0.70.30.4-0.2
Intermittent access total infusions0.10.20.60.8-0.70.6-0.5-0.2-0.60.00.2-0.4-0.4-0.4-0.3-0.20.20.40.20.40.1-0.1-0.1-0.1
Intermittent access day 1 locomotion0.00.10.50.3-0.70.6-0.20.1-0.10.3-0.1-0.00.00.00.10.2-0.2-0.0-0.2-0.1-0.20.30.20.6
Intermittent access day 15 total locomotion0.00.10.50.7-0.40.5-0.40.1-0.00.2-0.1-0.20.00.00.10.1-0.10.1-0.1-0.0-0.00.1-0.00.3
Intermittent access total locomotion0.20.20.80.7-0.90.8-0.10.40.10.5-0.30.00.20.20.40.4-0.4-0.2-0.4-0.3-0.50.40.40.3
Intermittent access standard deviation0.10.50.80.4-0.90.90.40.70.60.8-0.70.60.60.60.70.7-0.7-0.7-0.7-0.8-0.80.80.8-0.8
Left kidney weight0.75.47.72.5-2.82.82.82.42.12.5-2.32.62.12.12.32.3-2.3-2.4-2.2-2.2-2.22.32.2-1.0
Right kidney weight0.85.710.42.5-2.72.73.22.42.22.5-2.43.02.22.22.12.3-2.3-2.5-2.2-2.0-2.32.42.1-1.1
Cocaine induced anxiety0.00.10.2-0.2-0.30.30.30.1-0.00.2-0.10.5-0.0-0.00.20.2-0.2-0.3-0.1-0.2-0.30.40.40.5
Post-drug Anxiety2.22.54.10.3-1.11.11.91.51.61.4-1.52.01.71.71.71.6-1.6-1.9-1.6-1.7-2.01.71.8-0.7
Baseline Anxiety1.72.84.80.7-1.21.32.21.61.71.5-1.62.22.02.01.61.7-1.7-1.9-1.6-1.5-1.91.81.7-1.4
Tail length0.73.75.10.8-1.92.21.91.91.72.1-1.91.91.91.92.02.0-2.0-2.0-2.0-1.9-2.32.12.2-0.5
Length with tail1.35.77.90.5-2.12.52.62.42.22.5-2.42.62.32.32.42.6-2.6-2.5-2.5-2.4-2.72.72.8-0.5
Length without tail0.63.34.40.7-1.71.91.91.91.82.0-1.92.01.81.81.82.0-2.0-1.9-2.0-1.9-1.82.12.0-0.0
Times rat made contact with spout0.20.20.50.70.2-0.2-0.2-0.4-0.4-0.40.4-0.2-0.6-0.6-0.3-0.50.50.30.60.50.3-0.6-0.6-0.7
Lifetime Intake0.10.10.40.5-0.60.6-0.5-0.1-0.50.10.2-0.3-0.4-0.4-0.2-0.20.20.30.20.3-0.10.0-0.10.0
Liver weight, left0.10.10.40.2-0.40.60.50.30.10.5-0.30.20.00.00.40.3-0.4-0.3-0.3-0.30.00.50.3-0.5
Liver weight, right0.20.32.01.1-1.41.2-0.00.3-0.20.6-0.2-0.0-0.1-0.10.20.2-0.30.0-0.2-0.00.00.50.30.0
Locomotor activity0.10.21.3-0.21.2-0.8-0.4-0.30.0-0.50.3-0.2-0.2-0.2-0.2-0.40.40.30.40.20.4-0.7-0.6-0.1
Locomotor testing distance0.20.42.1-0.81.5-1.2-0.9-0.40.0-0.70.3-0.7-0.1-0.1-0.3-0.40.40.50.30.20.5-0.8-0.7-0.5
Locomotor testing rearing0.41.54.4-2.02.1-2.0-1.3-1.2-0.7-1.41.1-1.1-1.0-1.0-0.9-1.11.11.01.00.91.0-1.2-1.00.1
Locomotion in novel chamber0.00.00.10.20.00.10.4-0.0-0.1-0.00.10.2-0.0-0.0-0.2-0.10.10.00.10.10.1-0.1-0.20.1
Locomotion in novel chamber post-restriction0.00.12.0-1.40.6-0.4-0.1-0.2-0.2-0.20.2-0.10.00.0-0.3-0.00.00.20.10.20.10.10.00.4
Fecal boli incidents, locomotor time 10.10.32.01.1-0.30.4-0.1-0.2-0.4-0.20.3-0.1-0.7-0.7-0.4-0.40.40.30.40.40.4-0.3-0.5-1.4
Change in fecal boli incidents, locomotor task1.61.712.1-3.51.5-1.6-1.5-1.3-1.2-1.11.2-1.5-1.1-1.1-0.6-0.80.80.90.80.50.4-0.5-0.01.3
Time >=10cm from walls, locomotor time 10.10.22.3-1.50.5-0.3-0.1-0.3-0.3-0.20.2-0.10.10.1-0.1-0.10.00.20.10.10.10.20.2-0.4
Bouts of movement, locomotor time 10.40.52.41.6-0.80.90.80.70.70.7-0.70.70.60.60.70.5-0.5-0.7-0.5-0.5-0.60.40.4-0.2
Total resting periods, locomotor time 10.40.41.91.4-0.70.80.70.70.70.6-0.60.60.50.50.70.5-0.5-0.6-0.5-0.6-0.60.40.4-0.7
Rest time, locomotor task time 10.10.22.51.6-0.60.50.50.40.30.4-0.30.40.10.10.40.2-0.2-0.4-0.2-0.5-0.30.10.1-0.3
Distance moved, locomotor task time 10.51.54.1-2.01.3-1.3-1.3-1.4-1.4-1.21.3-1.3-1.3-1.3-1.2-1.11.11.31.11.21.0-0.8-0.8-0.2
Vertical activity count, locomotor time 10.10.63.7-1.9-0.00.30.50.40.30.6-0.40.50.90.90.50.7-0.8-0.6-0.7-0.4-0.61.10.90.5
Time >=10cm from walls, locomotor time 20.41.11.7-0.80.7-0.7-1.0-1.1-1.3-1.01.2-0.9-1.1-1.1-1.2-1.01.01.21.11.21.3-0.8-1.10.3
Bouts of movement, locomotor time 20.30.91.3-0.2-0.70.70.80.90.90.9-0.90.71.01.00.91.0-1.0-0.9-1.0-0.9-1.11.11.1-1.1
Total resting periods, locomotor time 20.20.61.0-0.1-0.70.60.60.70.70.8-0.80.60.90.90.80.9-0.9-0.7-0.9-0.8-1.01.00.9-0.7
Rest time, locomotor task time 20.40.71.00.8-0.90.70.71.01.00.9-1.00.70.90.90.80.9-0.9-0.9-1.0-1.0-0.50.80.70.1
Distance moved, locomotor task time 20.70.91.5-0.30.7-0.7-0.7-1.0-1.1-1.01.1-0.9-1.1-1.1-1.2-1.01.01.11.11.20.9-0.8-1.0-0.9
Vertical activity count, locomotor time 20.10.30.9-0.7-0.30.50.90.40.30.5-0.40.90.70.70.20.6-0.6-0.5-0.5-0.1-0.50.90.6-0.5
Light reinforcement 10.20.81.61.30.3-0.5-0.5-0.8-0.9-0.90.9-0.6-0.9-0.9-1.1-1.11.10.81.11.00.7-1.1-1.20.2
Light reinforcement 20.30.61.00.30.3-0.5-0.7-0.8-0.9-0.70.8-0.7-0.7-0.7-1.0-0.90.90.80.90.90.7-0.8-0.90.6
Bone: marrow area0.61.53.21.3-1.81.81.51.20.91.4-1.21.51.01.01.01.2-1.2-1.2-1.1-1.1-0.91.41.2-0.1
Bone: maximum diameter0.10.32.61.2-0.60.60.60.30.10.4-0.30.50.00.00.00.2-0.2-0.1-0.1-0.10.20.2-0.11.6
Bone: maximum force1.01.95.02.2-2.02.01.61.41.01.6-1.31.61.11.11.11.3-1.3-1.3-1.2-1.1-0.71.40.90.1
Bone: maximum moment0.81.54.52.1-1.81.81.41.20.81.4-1.11.40.90.90.91.1-1.1-1.1-1.0-0.9-0.51.20.70.5
Mean time between licks in bursts0.00.10.70.1-0.40.2-0.0-0.0-0.20.10.0-0.1-0.0-0.0-0.10.1-0.10.1-0.00.2-0.00.20.0-0.8
Mean num. licks in bursts0.00.00.20.4-0.30.3-0.0-0.0-0.20.10.00.1-0.2-0.20.1-0.00.0-0.00.00.0-0.30.0-0.00.1
Cd content in liver0.10.11.40.40.3-0.2-0.4-0.10.0-0.30.1-0.4-0.1-0.1-0.1-0.30.30.20.20.1-0.1-0.5-0.2-1.2
Co content in liver2.42.83.7-0.71.8-1.9-1.7-1.7-1.6-1.81.7-1.7-1.7-1.7-1.7-1.81.81.81.81.71.5-1.9-1.90.3
Cu content in liver0.10.10.40.10.3-0.10.30.20.50.1-0.30.40.30.30.40.2-0.2-0.3-0.3-0.40.10.1-0.1-0.7
Fe content in liver0.40.50.9-0.60.8-0.8-0.8-0.7-0.6-0.70.7-0.8-0.6-0.6-0.6-0.60.60.70.60.60.7-0.7-0.80.9
K content in liver0.30.30.50.0-0.40.30.40.50.60.5-0.60.40.70.70.60.6-0.6-0.5-0.6-0.6-0.60.60.4-0.0
Mg content in liver0.10.10.4-0.60.3-0.3-0.00.10.30.1-0.20.00.30.30.30.2-0.2-0.2-0.3-0.3-0.10.20.1-0.4
Mn content in liver2.93.34.8-2.22.0-2.2-2.2-1.9-1.8-1.91.9-2.1-1.8-1.8-1.7-1.71.71.91.71.71.6-1.7-1.5-0.0
Na content in liver0.20.20.50.3-0.70.60.10.50.40.6-0.50.10.50.50.50.6-0.6-0.3-0.6-0.5-0.30.60.50.0
Rb content in liver0.50.63.4-1.60.9-0.8-0.5-0.8-0.7-0.70.7-0.5-0.6-0.6-0.6-0.50.50.50.60.60.6-0.2-0.4-1.8
Se content in liver0.80.94.2-0.70.8-1.1-1.3-0.8-0.8-0.80.8-1.3-0.7-0.7-0.7-0.80.91.00.80.70.8-1.0-0.72.0
Sr content in liver0.00.00.1-0.0-0.30.1-0.10.10.00.1-0.1-0.10.10.10.10.1-0.10.0-0.1-0.1-0.10.10.10.1
Zn content in liver0.10.20.70.8-0.20.30.40.50.60.3-0.40.50.50.50.50.3-0.3-0.4-0.4-0.5-0.30.20.1-0.2
Bone: minimum diameter0.20.51.81.3-1.01.00.60.70.40.9-0.60.60.40.40.50.6-0.6-0.5-0.6-0.5-0.30.70.40.7
Time in familiar zone, hab. session 10.40.51.50.8-0.90.90.90.70.60.7-0.60.90.60.60.40.6-0.6-0.6-0.6-0.4-0.10.60.41.2
Time in novel zone, hab. session 10.10.11.9-0.30.2-0.4-0.5-0.2-0.1-0.20.1-0.5-0.1-0.10.1-0.10.10.20.0-0.0-0.4-0.10.1-1.4
Total zone transitions, hab. session 10.10.21.70.3-0.40.10.10.40.50.3-0.40.20.50.50.40.4-0.4-0.3-0.4-0.4-0.30.30.3-1.3
Total locomotion distance, hab. session 10.30.41.10.9-1.00.70.40.70.60.6-0.70.40.70.70.60.6-0.6-0.5-0.7-0.6-0.60.50.5-0.0
Locomotion velocity, hab. session 10.20.30.90.7-0.90.70.50.60.60.6-0.60.40.60.60.60.6-0.6-0.5-0.6-0.5-0.50.50.5-0.1
Time in familiar zone, hab. session 20.10.10.40.3-0.60.40.30.1-0.10.2-0.00.6-0.0-0.0-0.00.1-0.1-0.2-0.00.0-0.10.30.20.6
Time in novel zone, hab. session 20.30.31.50.7-0.10.20.30.60.80.4-0.60.10.60.60.70.4-0.4-0.4-0.5-0.6-0.30.10.2-1.2
Total zone transitions, hab. session 20.30.40.70.8-0.80.60.40.70.70.7-0.70.30.70.70.60.6-0.6-0.4-0.7-0.5-0.70.50.5-0.9
Total locomotion distance, hab. session 20.60.82.61.6-1.31.10.80.90.90.9-0.90.70.80.80.70.8-0.8-0.7-0.8-0.7-0.70.70.5-0.5
Locomotion velocity, hab. session 20.40.52.41.6-1.31.00.60.70.60.8-0.70.40.60.60.50.6-0.6-0.4-0.6-0.4-0.50.50.3-0.3
Novel to familiar place preference ratio0.40.50.8-0.70.7-0.7-0.7-0.8-0.9-0.70.8-0.8-0.9-0.9-0.6-0.70.70.70.70.60.8-0.6-0.60.6
Novelty place preference0.91.11.6-0.40.8-0.8-1.1-1.1-1.2-1.01.1-1.2-1.2-1.2-1.0-1.11.11.11.11.01.2-1.0-1.11.0
Time in novel zone, NPP test1.21.42.0-0.40.8-0.9-1.3-1.2-1.4-1.11.2-1.4-1.4-1.4-1.1-1.21.21.31.21.21.4-1.2-1.21.3
Total zone transitions, NPP test0.10.10.8-0.90.5-0.6-0.7-0.2-0.0-0.30.1-0.80.10.1-0.0-0.10.10.40.10.20.0-0.3-0.1-0.0
Total locomotion distance, NPP test0.10.10.80.30.1-0.3-0.6-0.2-0.1-0.30.2-0.6-0.1-0.1-0.2-0.30.30.40.20.30.3-0.5-0.40.9
Locomotion velocity, NPP test0.00.10.40.3-0.2-0.0-0.20.20.40.1-0.2-0.20.30.30.20.1-0.10.0-0.2-0.2-0.1-0.10.00.6
Intraocular pressure0.91.43.5-0.91.9-1.7-1.5-1.1-0.7-1.31.0-1.6-0.9-0.9-1.0-1.21.21.21.01.01.0-1.5-1.20.4
Delta distance traveled before/after self-admin1.71.93.20.9-1.71.81.51.41.21.6-1.41.51.41.41.11.4-1.4-1.3-1.4-1.1-1.11.61.3-0.6
Delta ambulatory time before/after self-admin1.22.03.21.0-1.81.81.61.51.21.6-1.41.61.51.51.11.5-1.5-1.4-1.4-1.1-1.11.61.3-0.4
Parametrial fat weight1.63.75.41.2-1.82.12.32.01.82.1-1.92.31.91.91.92.0-2.0-2.0-2.0-1.8-1.52.21.9-1.8
Pavlov. Cond. lever latency1.92.43.1-1.71.4-1.4-1.5-1.7-1.8-1.51.7-1.4-1.7-1.7-1.6-1.51.51.51.61.61.5-1.2-1.21.4
Pavlov. Cond. magazine entry latency7.19.113.01.1-2.32.53.03.13.33.0-3.12.83.23.23.33.2-3.1-3.1-3.2-3.2-3.63.03.3-2.9
Pavlov. Cond. change in total contacts3.03.25.01.3-1.31.41.42.02.21.8-2.01.42.12.12.11.9-1.9-1.8-2.0-2.2-1.71.51.7-1.3
Pavlov. Cond. index score6.17.79.91.3-2.12.32.82.93.12.7-2.92.63.13.13.02.9-2.9-2.8-2.9-3.0-3.12.72.9-2.4
Pavlov. Cond. latency score4.25.47.11.2-1.81.92.32.42.62.3-2.52.12.62.62.52.4-2.4-2.4-2.4-2.5-2.72.22.3-2.1
Pavlov. Cond. lever contacts2.93.54.61.5-1.61.71.92.02.11.9-2.01.72.12.12.01.9-1.9-1.9-2.0-2.0-2.11.71.7-1.4
Pavlov. Cond. magazine entry number5.46.98.9-1.01.8-2.0-2.7-2.7-3.0-2.52.8-2.5-2.9-2.9-2.9-2.82.72.72.82.83.0-2.6-2.72.4
Pavlov. Cond. intertrial magazine entries1.11.43.31.80.3-0.5-0.8-0.8-0.9-1.00.9-0.8-1.1-1.1-1.2-1.31.31.01.21.11.6-1.6-1.81.1
Pavlov. Cond. lever-magazine prob. diff.6.68.210.61.3-2.22.32.83.03.22.8-3.02.73.23.23.13.0-3.0-3.0-3.1-3.1-3.32.83.0-2.3
Pavlov. Cond. response bias5.97.49.41.9-2.22.32.82.93.12.7-2.92.73.03.02.92.8-2.8-2.8-2.8-2.8-2.92.52.6-2.5
Pavlov. Cond. lever latency0.10.21.3-1.10.6-0.5-0.4-0.5-0.5-0.40.4-0.3-0.4-0.4-0.4-0.30.30.40.30.40.1-0.1-0.2-0.1
Pavlov. Cond. magazine entry latency0.30.41.51.2-1.21.00.50.60.40.7-0.60.30.40.40.50.5-0.5-0.4-0.5-0.4-0.50.60.4-0.0
Pavlov. Cond. change in total contacts0.71.62.40.2-0.90.91.11.31.51.3-1.41.01.51.51.51.4-1.4-1.4-1.5-1.5-1.31.31.50.2
Pavlov. Cond. index score0.10.10.90.9-0.60.50.30.30.30.3-0.30.00.30.30.30.2-0.2-0.2-0.3-0.2-0.10.10.10.2
Pavlov. Cond. latency score0.10.10.50.7-0.60.50.20.30.30.4-0.3-0.00.30.30.30.3-0.3-0.2-0.3-0.2-0.20.20.20.4
Pavlov. Cond. lever contacts0.00.10.90.9-0.40.30.20.20.20.1-0.10.00.10.10.10.0-0.0-0.1-0.0-0.10.1-0.1-0.10.2
Pavlov. Cond. magazine entry number1.11.53.0-1.71.5-1.4-1.2-1.3-1.3-1.31.3-1.1-1.2-1.2-1.3-1.21.21.21.21.21.1-1.0-1.0-0.1
Pavlov. Cond. intertrial magazine entries0.91.92.5-0.31.0-1.0-1.3-1.5-1.6-1.41.5-1.3-1.5-1.5-1.6-1.51.51.51.51.51.2-1.4-1.40.9
Pavlov. Cond. lever-magazine prob. diff.0.10.11.11.0-0.60.50.30.40.30.3-0.30.10.30.30.30.2-0.2-0.2-0.3-0.2-0.10.10.10.1
Pavlov. Cond. response bias0.50.71.81.3-1.10.90.90.90.90.8-0.90.70.80.80.80.8-0.8-0.8-0.8-0.8-0.60.60.7-0.3
Time in closed arm before self-admin0.10.10.6-0.80.30.0-0.3-0.2-0.4-0.10.3-0.5-0.1-0.1-0.3-0.10.10.50.20.40.30.1-0.10.0
Time in closed arm after self-admin0.30.43.7-1.91.0-0.5-0.6-0.5-0.4-0.40.4-0.60.00.0-0.4-0.20.20.40.20.30.4-0.10.00.9
Time in open arm before self-admin0.40.51.41.2-0.80.51.00.70.70.7-0.70.90.60.60.50.6-0.6-0.8-0.6-0.6-0.60.50.4-1.0
Time in open arm after self-admin0.70.81.5-0.30.4-0.8-0.8-0.9-1.1-0.81.0-0.9-1.2-1.2-1.0-0.90.91.00.91.01.0-0.8-1.0-0.5
Bone: periosteal estimation0.10.31.71.3-0.91.00.60.40.10.6-0.30.60.10.10.00.3-0.3-0.3-0.2-0.10.20.40.10.6
Bone: periosteal perimeter0.10.10.80.8-0.40.50.40.1-0.10.2-0.10.3-0.1-0.1-0.10.0-0.0-0.00.00.00.20.1-0.20.9
Bone: post-yield work1.11.93.11.5-1.71.81.31.51.31.6-1.51.21.41.41.31.4-1.4-1.2-1.4-1.4-1.21.31.20.7
Progressive ratio test 1 active lever presses1.32.22.80.7-1.41.41.11.51.51.5-1.51.31.51.51.61.6-1.6-1.5-1.6-1.6-1.71.61.6-1.4
Progressive ratio test 1 breakpoint1.42.43.00.7-1.51.51.21.61.61.6-1.61.41.61.61.61.7-1.7-1.6-1.7-1.7-1.71.71.7-1.5
Progressive ratio test 1 inactive lever presses0.20.61.71.0-1.31.30.80.70.50.9-0.70.90.50.50.50.7-0.8-0.7-0.7-0.6-0.70.90.7-0.5
Progressive ratio test 2 active lever presses0.20.30.70.2-0.70.80.30.50.30.7-0.50.40.40.40.80.6-0.6-0.6-0.6-0.6-0.80.80.80.1
Progressive ratio test 2 breakpoint0.20.30.70.2-0.70.80.30.50.20.6-0.40.40.30.30.70.5-0.5-0.5-0.5-0.5-0.70.70.70.1
Progressive ratio test 2 inactive lever presses0.20.87.02.7-1.41.30.1-0.2-0.90.10.40.1-0.8-0.8-0.7-0.50.50.40.60.80.7-0.3-0.90.3
Incentive Sensitization - Responses0.10.21.3-0.60.2-0.1-0.4-0.5-0.7-0.30.5-0.3-0.4-0.4-0.3-0.40.40.40.40.50.4-0.2-0.31.1
Incentive Sensitization - Breakpoint0.20.41.9-0.60.4-0.3-0.6-0.7-0.9-0.50.7-0.5-0.7-0.7-0.5-0.60.60.60.60.70.6-0.4-0.51.4
Sum of active levers in priming session hrs 5-60.20.20.8-0.90.3-0.1-0.20.20.40.2-0.3-0.20.50.50.30.4-0.4-0.2-0.5-0.3-0.10.40.3-0.6
Progressive ratio0.10.42.61.6-0.10.1-0.9-0.3-0.4-0.30.3-0.8-0.5-0.5-0.5-0.60.60.70.50.50.3-0.8-0.7-0.1
Food seeking constrained by brief footshock0.40.54.52.1-0.50.50.2-0.2-0.5-0.20.30.3-0.4-0.4-0.8-0.50.50.40.60.80.8-0.5-0.90.2
Seeking ratio, punishment vs. effort0.10.10.8-0.50.1-0.10.6-0.3-0.3-0.20.30.5-0.2-0.2-0.4-0.20.10.00.30.40.60.1-0.30.9
Retroperitoneal fat weight0.20.76.42.5-1.51.50.90.80.30.9-0.60.80.30.30.20.4-0.4-0.4-0.4-0.10.10.4-0.00.4
Reaction time number correct0.00.11.10.90.1-0.1-0.4-0.1-0.1-0.20.1-0.4-0.1-0.1-0.1-0.30.30.20.20.20.3-0.5-0.41.0
Reaction time mean minus median0.32.13.4-1.81.7-1.8-1.7-1.5-1.3-1.61.4-1.8-1.4-1.4-1.2-1.41.41.41.41.11.1-1.5-1.01.1
Reaction time mean minus median AUC0.21.45.2-2.31.8-1.8-1.3-1.1-0.7-1.21.0-1.4-0.9-0.9-0.6-0.90.90.80.80.50.6-1.1-0.51.4
Reaction time num false alarms0.00.10.30.20.5-0.50.1-0.10.2-0.30.00.1-0.1-0.1-0.1-0.20.20.00.20.1-0.2-0.4-0.3-0.2
Reaction time num false alarms AUC0.00.10.20.50.3-0.30.20.20.4-0.1-0.20.20.10.10.2-0.00.0-0.2-0.0-0.2-0.4-0.3-0.1-0.1
Reaction time trials correct on left0.00.11.10.90.1-0.1-0.4-0.1-0.1-0.20.1-0.4-0.1-0.1-0.1-0.30.30.20.20.20.3-0.5-0.41.0
Reaction time trials on left0.00.21.00.90.2-0.1-0.5-0.1-0.1-0.20.1-0.4-0.1-0.1-0.2-0.30.30.30.20.20.3-0.6-0.51.0
Reaction time mean0.10.11.4-1.20.5-0.60.1-0.00.2-0.1-0.0-0.10.10.10.10.1-0.1-0.1-0.1-0.2-0.10.10.2-0.4
Reaction time mean AUC0.10.22.2-1.50.7-0.7-0.1-0.20.1-0.30.1-0.4-0.0-0.00.00.00.00.1-0.0-0.10.00.00.2-0.2
Median of all reaction times0.40.61.2-0.4-0.30.30.90.70.90.6-0.80.60.80.80.70.8-0.8-0.8-0.8-0.8-0.60.80.8-1.1
Reaction time omissions0.71.12.20.50.9-1.0-0.7-0.9-0.7-1.10.9-0.9-0.9-0.9-1.2-1.11.11.01.11.11.3-1.3-1.5-1.1
Reaction time false alarm rate0.10.10.5-0.10.3-0.20.50.30.50.1-0.30.50.20.20.30.3-0.3-0.4-0.3-0.3-0.60.20.3-0.7
Reaction time premature initiation rate1.21.85.0-2.21.4-1.5-1.6-1.5-1.4-1.41.4-1.5-1.3-1.3-1.0-1.21.21.31.21.01.3-1.1-0.90.5
Reaction time premature initiations0.61.73.0-1.71.4-1.5-1.7-1.4-1.3-1.41.3-1.5-1.2-1.2-1.0-1.21.21.31.21.01.3-1.2-1.00.6
Std. dev. reaction times0.41.22.1-1.21.3-1.4-1.2-1.1-0.9-1.21.1-1.3-1.1-1.1-1.0-1.11.11.01.00.81.0-1.2-0.90.6
Reaction time trials completed0.00.21.00.90.2-0.1-0.5-0.1-0.1-0.20.1-0.4-0.1-0.1-0.2-0.30.30.30.20.20.3-0.6-0.51.0
Reaction time trials AUC0.00.11.01.00.10.0-0.30.00.1-0.1-0.0-0.20.00.0-0.0-0.20.20.10.10.10.2-0.4-0.40.8
Run reversals in cocaine runway, females0.20.20.7-0.8-0.10.10.20.30.30.3-0.30.20.40.40.50.4-0.4-0.3-0.5-0.5-0.40.50.60.5
Run reversals in cocaine runway, males0.10.21.11.0-0.10.0-0.00.30.50.1-0.30.00.50.50.10.1-0.1-0.1-0.2-0.20.2-0.2-0.21.0
Latency to leave start box in cocaine runway1.62.23.5-0.81.5-1.6-1.2-1.5-1.4-1.51.5-1.1-1.5-1.5-1.8-1.51.51.51.51.81.9-1.5-1.80.8
Latency to leave start box in cocaine runway, F0.60.81.70.00.6-0.7-0.4-0.9-0.9-0.80.9-0.3-1.1-1.1-1.2-0.90.90.90.91.11.3-0.8-1.30.5
Latency to leave start box in cocaine runway, M1.81.73.0-1.31.7-1.7-1.3-1.3-1.1-1.51.3-1.3-1.1-1.1-1.4-1.31.31.31.31.41.3-1.3-1.40.6
Std. dev. time between licks in bursts1.01.82.8-0.10.9-1.0-1.3-1.4-1.5-1.31.4-1.4-1.5-1.5-1.4-1.51.51.51.51.61.7-1.4-1.50.3
Total sessions with >9 infusions0.20.31.30.7-1.11.10.20.40.10.7-0.40.50.10.10.30.4-0.4-0.3-0.4-0.3-0.60.60.60.4
Short access day 1 total inactive lever presses0.81.512.73.6-2.12.00.91.10.61.2-1.01.00.70.70.80.7-0.7-0.8-0.7-0.7-0.90.50.30.6
Short access day 10 total inactive lever presses0.00.20.80.6-0.50.50.90.20.10.3-0.10.90.00.00.10.2-0.2-0.4-0.1-0.1-0.10.30.10.8
Short access day 1 total infusions0.10.20.40.2-0.50.60.20.40.30.4-0.40.40.30.30.50.4-0.4-0.4-0.4-0.4-0.60.40.50.5
Short access day 10 total infusions0.20.31.00.9-1.00.80.00.50.30.6-0.40.00.30.30.30.4-0.4-0.3-0.4-0.4-0.40.50.4-0.8
Short access total infusions0.00.10.20.3-0.40.4-0.5-0.1-0.30.10.1-0.3-0.3-0.3-0.2-0.10.10.30.10.2-0.1-0.0-0.00.2
Short access day 1 locomotion0.20.30.90.4-1.00.7-0.00.40.20.5-0.40.20.10.10.60.4-0.4-0.4-0.4-0.5-0.90.60.8-0.4
Short access day 10 total locomotion0.62.44.11.2-2.01.91.31.61.41.7-1.61.41.51.51.61.6-1.6-1.5-1.6-1.6-1.81.71.7-0.2
Short access total locomotion0.30.41.80.8-1.41.20.20.60.20.8-0.50.40.20.20.50.6-0.6-0.5-0.6-0.6-0.80.80.80.1
One hour access (0.3 mA shock)0.10.10.4-0.2-0.60.6-0.50.1-0.30.4-0.1-0.5-0.0-0.00.30.3-0.30.1-0.3-0.2-0.50.50.5-0.6
Compulsive drug intake0.40.52.4-1.51.1-1.0-1.4-0.6-0.5-0.60.5-1.4-0.4-0.4-0.1-0.40.40.80.30.30.1-0.5-0.20.0
One hour access (shock baseline)0.10.31.81.1-1.31.10.30.2-0.30.5-0.10.3-0.1-0.10.00.2-0.2-0.1-0.1-0.0-0.10.50.2-0.3
Social response proportion0.20.20.7-0.70.00.0-0.4-0.5-0.8-0.20.5-0.2-0.6-0.6-0.5-0.30.30.40.40.6-0.1-0.0-0.10.4
Social responses1.72.24.10.60.5-0.5-1.0-1.5-1.9-1.31.6-0.9-2.0-2.0-1.7-1.71.71.41.81.81.3-1.5-1.71.5
Social time0.61.02.11.4-0.40.2-0.9-0.8-1.2-0.60.9-1.1-1.3-1.3-1.1-1.01.01.01.11.10.9-1.0-1.10.6
Soleus weight4.212.314.92.8-3.83.93.93.63.43.7-3.63.73.43.43.53.6-3.6-3.6-3.5-3.5-3.43.73.5-2.1
Bone: stiffness1.93.55.11.9-2.32.32.22.01.72.1-1.92.11.71.71.81.9-1.9-1.9-1.8-1.7-1.42.01.6-0.7
Tibialis anterior weight1.34.66.1-0.2-1.31.62.42.12.32.0-2.12.32.32.32.32.3-2.3-2.3-2.2-2.3-2.32.42.5-1.9
Time to tail flick, vehicle, before self-admin0.20.21.1-1.10.8-0.30.1-0.6-0.5-0.50.60.0-0.6-0.6-0.4-0.40.40.20.50.40.1-0.2-0.10.1
Time to tail flick, vehicle, after self-admin0.20.41.1-0.90.2-0.20.2-0.7-1.0-0.40.70.1-0.8-0.8-0.8-0.50.50.40.70.70.8-0.0-0.4-0.3
Time to tail flick, test, before self-admin0.10.11.2-1.10.30.20.2-0.0-0.00.1-0.00.10.00.00.30.2-0.2-0.1-0.1-0.2-0.30.40.5-0.8
Time to tail flick, test, after self-admin0.20.21.30.8-1.11.20.20.2-0.30.5-0.20.20.10.1-0.20.2-0.2-0.0-0.20.10.20.50.10.1
Delta time to tail flick, vehicle, before/after SA0.10.11.81.4-0.70.40.30.2-0.10.2-0.10.30.10.1-0.2-0.00.0-0.00.10.10.4-0.1-0.40.2
Delta time to tail flick, test, before/after SA0.40.54.92.2-1.10.70.1-0.2-0.6-0.00.30.2-0.4-0.4-0.8-0.40.40.40.50.80.9-0.3-0.90.3
Tibia length3.49.411.3-3.13.4-3.3-3.1-3.2-3.0-3.23.1-3.0-3.1-3.1-2.9-3.03.03.03.02.93.1-2.9-2.83.0
Ambulatory time before self-admin0.61.72.9-1.01.7-1.7-1.4-1.3-1.1-1.41.3-1.3-1.1-1.1-1.3-1.31.31.41.31.31.4-1.4-1.40.1
Ambulatory time after self-admin0.10.10.9-0.90.0-0.1-0.3-0.1-0.20.00.1-0.30.10.1-0.40.1-0.10.3-0.00.40.40.3-0.1-0.4
Bone: tissue strength0.20.20.5-0.40.4-0.5-0.5-0.5-0.6-0.40.5-0.4-0.6-0.6-0.5-0.50.40.50.50.50.4-0.4-0.40.7
Total heroin consumption0.70.81.40.6-0.60.80.71.11.21.0-1.10.81.11.10.81.0-1.0-0.9-1.1-0.9-0.80.80.8-0.5
Bone: trabecular number0.81.54.70.5-0.91.11.11.21.41.2-1.30.91.31.31.21.3-1.3-1.1-1.2-1.3-1.21.21.2-2.2
Bone: trabecular spacing2.74.011.1-1.01.8-2.0-2.1-1.9-1.8-1.91.9-2.1-1.8-1.8-1.8-1.91.92.01.81.82.1-2.1-2.13.3
Bone: trabecular thickness0.30.43.70.0-0.30.50.50.50.50.5-0.50.40.40.40.50.5-0.5-0.4-0.5-0.5-0.50.70.6-1.9
Bone: trabecular tissue density1.22.13.60.1-0.81.01.91.51.71.4-1.51.91.61.61.51.6-1.6-1.7-1.5-1.6-1.11.61.5-0.7
Water consumed over 24 hours0.51.01.60.31.0-0.9-1.0-1.0-0.9-1.11.0-0.9-1.2-1.2-0.9-1.21.20.91.21.01.0-1.3-1.2-0.5
Number of responses in last shaping day4.15.36.92.6-2.52.42.12.42.52.3-2.42.22.32.32.32.3-2.3-2.3-2.3-2.4-2.32.12.0-2.1