Adamts20

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL gene expression Adamts20 0.62 0.22 1.9e-03 0.08 0.06 0.14 0.09 5.2e-03 1.5e-02 3.2e-04 2.9e-03
2 LHb isoform ratio NM_001421315.1 0.58 0.28 1.8e-05 0.13 0.13 0.14 0.14 5.4e-04 5.5e-04 3.2e-04 4.1e-04
3 LHb isoform ratio XM_039080336.1 0.54 0.31 1.8e-04 0.1 0.1 0.11 0.11 1.9e-03 2.7e-03 1.2e-03 1.5e-03
4 NAcc gene expression Adamts20 0.04 0.03 1.4e-04 0.03 0.02 0.01 0.02 2.9e-05 3.7e-04 1.0e-02 1.6e-04
5 Brain isoform ratio NM_001421315.1 0.03 0.03 6.6e-03 0.01 0.02 0.02 0.01 2.2e-02 7.3e-03 1.0e-02 2.2e-02
6 NAcc intron excision ratio chr7_127277490_127280787 0.04 0.03 2.0e-05 0.02 0.03 0.02 0.03 3.4e-04 1.7e-05 1.1e-04 9.8e-05
7 Brain intron excision ratio chr7_127277490_127280787 0.08 0.06 8.9e-08 0.06 0.08 0.07 0.07 1.4e-06 9.7e-08 1.9e-07 2.1e-07
8 OFC gene expression Adamts20 0.16 0.14 5.8e-03 0.04 0.04 -0.01 0.03 3.9e-02 3.3e-02 6.6e-01 6.7e-02
9 PL gene expression Adamts20 0.1 0.09 1.5e-09 0.09 0.09 0.09 0.09 4.2e-10 7.7e-10 7.9e-10 5.0e-10
10 NAcc isoform ratio XM_039080336.1 0.04 0.03 3.4e-07 0.05 0.04 0.04 0.04 4.2e-08 2.5e-07 9.9e-07 3.0e-07
11 PL alternative TSS XM_039080336.1 0.02 0.02 9.4e-04 0.03 0.02 0.02 0.03 4.3e-04 2.0e-03 1.8e-03 8.5e-04
12 pVTA gene expression Adamts20 0.11 0.09 5.9e-07 0.09 0.08 0.06 0.08 9.7e-08 7.6e-07 1.1e-05 2.7e-07
13 pVTA isoform ratio NM_001421315.1 0.03 0.02 2.4e-03 0.01 0.03 0.02 0.02 2.4e-02 1.6e-03 8.4e-03 1.6e-02
14 pVTA isoform ratio XM_039080336.1 0.03 0.02 2.8e-03 0 0.02 0.01 0.01 1.6e-01 9.5e-03 2.9e-02 8.2e-02
15 Brain gene expression Adamts20 0.08 0.06 3.1e-07 0.07 0.07 0.06 0.07 5.7e-07 5.1e-07 1.5e-06 4.5e-07
16 PL isoform ratio XM_039080336.1 0.06 0.04 1.0e-07 0.07 0.07 0.06 0.07 9.5e-08 2.2e-08 3.4e-07 9.2e-08
17 PL isoform ratio NM_001421315.1 0.02 0.01 7.2e-03 0.02 0.02 0.01 0.01 5.6e-03 6.8e-03 2.3e-02 1.7e-02
18 NAcc isoform ratio NM_001421315.1 0.03 0.02 9.6e-07 0.05 0.04 0.04 0.04 3.4e-08 2.3e-07 3.3e-07 4.4e-07
19 pVTA intron excision ratio chr7_127277490_127280787 0.11 0.08 2.6e-05 0.02 0.05 0.05 0.04 5.5e-03 5.8e-05 1.3e-04 2.6e-04
20 BLA gene expression Adamts20 0.1 0.07 7.5e-05 0.06 0.05 0.03 0.05 7.3e-04 7.5e-04 1.2e-02 1.2e-03
21 Brain isoform ratio XM_039080336.1 0.09 0.06 8.9e-10 0.08 0.09 0.1 0.09 6.0e-08 1.7e-08 3.7e-09 1.5e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density0.50.92.8-0.50.5-0.8-0.91.01.20.9-1.0-0.9-1.0-1.0-1.01.0-1.0-0.9-0.91.00.80.9-0.81.7
Area under the delay curve0.30.31.10.60.3-0.5-0.00.40.40.5-0.5-0.2-0.5-0.5-0.80.6-0.6-0.6-0.70.71.00.6-1.0-0.1
BMI with tail0.20.81.7-1.11.1-1.1-1.20.90.71.0-0.9-1.3-0.6-0.6-0.60.9-0.9-0.9-0.80.60.21.0-0.41.3
BMI without tail0.20.61.4-0.91.1-1.2-0.90.70.40.9-0.7-0.9-0.4-0.4-0.50.7-0.7-0.6-0.60.40.40.9-0.51.1
Body weight1.25.47.9-1.52.4-2.8-2.72.52.22.6-2.4-2.8-2.2-2.2-2.22.5-2.5-2.4-2.42.22.02.6-2.20.9
Weight adjusted by age0.50.81.8-0.10.9-0.8-0.40.90.91.0-0.9-0.3-0.8-0.8-1.21.0-1.0-0.9-1.11.11.30.9-1.3-0.1
Bone surface2.03.74.6-1.61.7-2.0-2.12.12.12.0-2.0-2.1-2.0-2.0-1.92.0-2.0-2.0-1.91.91.81.9-1.81.4
Bone volume1.01.82.6-1.00.9-1.2-1.41.41.61.3-1.4-1.4-1.4-1.4-1.41.4-1.4-1.3-1.31.41.11.2-1.21.6
Breakpoint value in progressive ratio session1.11.32.50.3-0.0-0.3-0.91.21.60.9-1.3-1.1-1.4-1.4-1.31.2-1.2-1.2-1.31.31.11.0-1.11.5
Number of licking bursts0.40.71.20.1-0.70.80.7-0.8-0.7-0.90.80.80.80.80.9-0.90.90.80.9-0.9-1.1-0.90.90.2
Context. condit. distance diff. score1.21.42.3-0.6-0.70.70.6-1.2-1.3-1.21.30.71.31.31.5-1.41.41.21.4-1.5-1.4-1.41.5-0.5
Locomotion velocity, session 10.40.40.8-0.5-0.10.00.6-0.5-0.8-0.40.60.70.70.70.8-0.70.70.80.7-0.8-0.9-0.60.8-0.5
Locomotion distance, session 10.30.30.70.50.2-0.2-0.30.50.70.5-0.6-0.2-0.7-0.7-0.70.6-0.6-0.5-0.70.60.80.6-0.80.8
Locomotion velocity, session 20.10.10.7-0.20.4-0.50.00.40.30.4-0.40.0-0.3-0.3-0.30.4-0.4-0.2-0.30.30.20.3-0.40.8
Locomotion distance, session 20.10.10.7-0.10.1-0.10.30.40.60.2-0.40.3-0.5-0.5-0.50.3-0.3-0.1-0.40.40.20.1-0.40.8
Locomotion velocity, session 30.40.53.1-1.80.2-0.10.2-0.3-0.5-0.40.40.30.60.60.8-0.70.70.60.7-0.7-0.7-0.81.00.1
Locomotion distance, session 33.03.34.70.4-1.71.81.6-1.8-1.7-1.91.81.61.81.82.0-2.02.01.92.0-2.0-2.0-2.12.2-1.1
Stereotopy head waving bouts, day 30.80.91.7-0.91.2-1.0-1.00.90.91.0-0.9-1.1-0.8-0.8-0.90.9-0.9-1.0-0.90.91.31.0-1.00.3
Stereotopy head waving duration, day 30.50.62.6-1.61.5-1.2-0.60.70.40.8-0.6-0.6-0.4-0.4-0.40.6-0.6-0.6-0.60.50.70.7-0.50.4
Locomotion velocity, session 72.02.22.9-1.61.5-1.5-1.61.61.61.5-1.5-1.7-1.5-1.5-1.51.4-1.4-1.6-1.41.41.41.2-1.30.5
Locomotion distance, session 70.30.41.70.3-0.80.70.5-0.5-0.4-0.70.50.40.30.30.5-0.60.60.50.6-0.6-0.7-0.80.7-1.3
Stereotopy head waving bouts, day 70.80.93.7-1.91.5-1.2-0.90.90.70.9-0.8-0.8-0.8-0.8-0.60.7-0.8-0.7-0.70.60.60.8-0.51.2
Stereotopy head waving duration, day 71.31.53.1-1.71.7-1.5-1.21.21.01.3-1.1-1.1-1.1-1.1-1.01.1-1.1-1.1-1.11.01.11.2-1.01.8
Locomotion velocity, session 81.31.52.3-1.21.3-1.5-1.51.31.31.3-1.3-1.4-1.4-1.4-1.21.2-1.2-1.2-1.11.10.81.2-1.10.7
Locomotion distance, session 81.01.52.4-0.3-0.90.91.0-1.2-1.2-1.21.21.21.11.11.5-1.41.41.41.4-1.5-1.5-1.51.5-0.6
Degree of sensitization distance1.91.92.6-0.41.3-1.4-1.31.41.41.5-1.4-1.3-1.5-1.5-1.51.5-1.5-1.4-1.51.51.51.5-1.60.1
Degree of sensitization stereotypy0.40.42.9-1.71.0-0.8-0.60.50.40.6-0.5-0.5-0.5-0.5-0.20.4-0.4-0.4-0.40.30.20.3-0.11.0
Conditioned locomotion0.10.11.01.00.1-0.20.10.1-0.10.2-0.1-0.00.10.1-0.20.2-0.3-0.1-0.20.30.30.5-0.50.1
Cocaine response after cond. corrected0.40.51.00.4-0.1-0.1-0.40.70.90.6-0.8-0.4-0.9-0.9-0.90.8-0.8-0.7-0.81.01.00.6-0.80.2
Cocaine response after cond. not corrected0.10.20.60.8-0.50.3-0.00.30.50.2-0.3-0.0-0.5-0.5-0.40.4-0.4-0.3-0.40.50.50.2-0.30.0
Cocaine response before conditioning1.82.23.30.5-1.11.21.2-1.5-1.6-1.51.61.21.51.51.7-1.61.61.61.6-1.8-1.8-1.51.7-0.7
Saline control response2.02.65.82.4-2.22.01.5-1.7-1.5-1.71.71.51.61.61.4-1.51.51.41.5-1.4-1.3-1.41.2-0.8
Bone: connectivity density2.84.35.5-1.01.6-1.9-1.92.22.42.2-2.3-2.0-2.3-2.3-2.22.3-2.3-2.2-2.32.32.02.2-2.11.5
Bone: cortical apparent density1.62.23.6-0.70.9-0.8-1.71.61.91.4-1.6-1.7-1.7-1.7-1.81.6-1.6-1.7-1.61.71.31.4-1.40.7
Bone: cortical area0.40.61.8-1.0-0.10.10.4-0.5-0.7-0.40.60.40.80.80.8-0.70.70.70.7-0.8-1.2-0.71.1-1.3
Bone: cortical porosity0.30.31.20.3-0.30.50.4-0.5-0.7-0.40.50.20.70.70.6-0.50.50.40.6-0.7-0.4-0.40.41.1
Bone: cortical porosity0.20.22.5-0.70.3-0.2-0.10.0-0.10.10.0-0.20.20.20.2-0.10.1-0.00.1-0.2-0.1-0.00.21.6
Bone: cortical thickness1.62.64.1-0.2-1.21.21.7-1.5-1.7-1.51.61.71.71.71.7-1.71.71.81.7-1.7-2.0-1.72.0-1.0
Bone: cortical thickness2.83.34.7-0.4-1.21.32.0-1.8-2.0-1.71.92.02.12.11.9-2.02.01.92.0-1.9-2.2-2.02.1-0.2
Bone: cortical tissue density1.72.33.7-0.70.9-0.9-1.81.61.91.4-1.7-1.7-1.7-1.7-1.81.6-1.6-1.7-1.61.81.31.4-1.40.8
Condit. Reinf. active minus inactive responses4.04.58.7-3.02.4-2.4-2.32.32.22.1-2.2-2.1-2.0-2.0-2.12.0-2.0-2.1-1.92.11.71.8-1.62.1
Condit. Reinf. active-inactive response ratio3.94.29.1-3.02.7-2.6-2.32.11.92.1-2.0-2.0-1.8-1.8-1.81.9-1.9-1.9-1.81.81.61.8-1.61.8
Condit. Reinf. active responses5.06.212.6-3.62.7-2.7-2.62.72.72.5-2.6-2.5-2.4-2.4-2.62.3-2.3-2.5-2.32.51.92.0-1.82.5
Condit. Reinf. inactive responses1.11.35.0-2.20.9-1.0-1.11.31.51.0-1.3-1.2-1.1-1.1-1.30.9-0.9-1.2-1.01.20.60.5-0.51.2
Incentive salience index mean4.04.97.4-2.72.4-2.4-2.32.42.42.3-2.3-2.0-2.2-2.2-2.32.1-2.1-2.1-2.12.21.91.9-1.82.2
Condit. Reinf. lever presses4.56.37.4-2.22.4-2.4-2.42.72.72.6-2.7-2.2-2.7-2.7-2.72.5-2.5-2.5-2.62.62.52.3-2.42.3
Condit. Reinf. active minus inactive responses0.00.00.0-0.1-0.00.10.20.00.1-0.0-0.10.1-0.1-0.1-0.10.0-0.0-0.1-0.10.10.2-0.1-0.00.1
Condit. Reinf. active-inactive response ratio0.30.30.6-0.5-0.30.50.5-0.5-0.5-0.60.50.40.60.60.6-0.60.70.50.6-0.5-0.6-0.80.80.2
Condit. Reinf. active responses0.71.01.5-0.30.9-0.9-0.81.01.11.0-1.1-0.8-1.1-1.1-1.11.1-1.1-1.0-1.11.11.20.9-1.20.3
Condit. Reinf. inactive responses1.01.42.2-0.11.1-1.1-1.01.21.21.2-1.2-0.8-1.2-1.2-1.41.3-1.3-1.1-1.31.21.41.3-1.50.4
Condit. Reinf. lever presses0.50.71.2-1.01.1-1.0-0.80.90.90.9-0.9-0.6-0.9-0.9-0.80.8-0.8-0.8-0.80.80.60.7-0.80.1
Condit. Reinf. lever reinforcers received0.40.60.9-0.50.7-0.7-0.60.80.90.8-0.9-0.6-0.9-0.9-0.90.8-0.8-0.8-0.90.90.90.7-0.80.3
Conditioned reinforcement - actives1.11.82.8-0.51.3-1.3-1.01.31.31.4-1.3-1.2-1.2-1.2-1.61.4-1.4-1.3-1.41.41.61.5-1.61.7
Conditioned reinforcement - inactives0.40.75.8-2.41.6-1.5-0.70.60.10.7-0.5-0.8-0.1-0.1-0.20.3-0.3-0.4-0.30.10.30.4-0.0-0.1
Conditioned locomotion0.20.30.60.3-0.20.30.8-0.6-0.7-0.50.60.70.80.80.5-0.60.50.60.5-0.7-0.2-0.50.4-0.6
Patch foraging indifference point 0 sec0.10.31.91.4-1.00.70.2-0.5-0.4-0.50.40.30.40.40.3-0.30.30.30.4-0.3-0.1-0.20.1-0.3
Patch foraging indifference point AUC0.20.21.30.3-0.30.30.2-0.5-0.6-0.40.50.40.70.70.2-0.50.50.30.5-0.2-0.4-0.30.21.1
Delay disc. indifference point, 0s delay1.61.84.92.2-1.61.51.3-1.6-1.6-1.51.61.31.31.30.9-1.31.31.21.4-1.3-0.6-1.00.7-0.4
Delay disc. indifference point, 16s delay4.44.86.5-0.61.9-2.2-2.12.22.22.2-2.2-2.1-2.2-2.2-2.42.3-2.3-2.4-2.32.52.52.4-2.61.8
Delay disc. indifference point, 2s delay0.30.33.71.9-0.80.40.6-0.5-0.4-0.40.40.30.30.3-0.0-0.10.10.20.1-0.10.10.1-0.3-0.1
Delay disc. indifference point, 24s delay2.93.24.4-0.01.1-1.1-1.61.92.11.8-2.0-1.6-2.0-2.0-2.02.0-2.0-2.0-2.12.02.11.9-2.10.5
Delay disc. indifference point, 4s delay0.50.62.41.6-0.80.50.9-0.9-0.9-0.80.90.90.80.80.4-0.60.60.70.7-0.6-0.5-0.40.30.0
Delay disc. indifference point, 8s delay0.10.21.50.8-0.30.20.8-0.2-0.1-0.20.10.60.10.1-0.2-0.10.10.1-0.00.10.4-0.1-0.3-1.2
Indifference point function ln k0.40.71.0-0.20.9-1.0-0.60.90.80.9-0.9-0.7-0.9-0.9-0.70.9-0.9-0.7-0.90.60.90.9-0.8-0.8
Indifference point function log k0.40.71.0-0.20.9-1.0-0.60.90.80.9-0.9-0.7-0.9-0.9-0.70.9-0.9-0.7-0.90.60.90.9-0.8-0.8
Patch foraging total patch changes 0 sec0.10.10.90.9-0.80.50.0-0.4-0.3-0.40.30.10.30.30.2-0.30.30.10.3-0.2-0.2-0.20.1-0.2
Patch foraging total patch changes 12 sec0.20.20.70.6-0.70.50.1-0.4-0.5-0.40.50.30.50.50.3-0.40.40.30.5-0.3-0.5-0.40.30.8
Patch foraging total patch changes 18 sec0.00.10.30.1-0.2-0.0-0.40.10.20.1-0.1-0.3-0.0-0.0-0.40.1-0.1-0.3-0.10.40.40.1-0.30.5
Patch foraging total patch changes 24 sec0.00.10.5-0.70.1-0.3-0.6-0.0-0.1-0.00.1-0.50.30.30.0-0.20.1-0.20.20.1-0.1-0.10.10.3
Patch foraging total patch changes 6 sec1.72.64.82.0-2.21.91.3-1.7-1.6-1.81.71.41.71.71.4-1.61.61.51.7-1.4-1.6-1.51.4-0.3
Patch foraging time to switch 0 sec0.10.11.01.0-0.80.60.1-0.20.1-0.30.10.1-0.0-0.00.3-0.10.10.20.1-0.2-0.2-0.10.2-0.3
Patch foraging water rate 0 sec0.10.20.5-0.30.2-0.20.6-0.4-0.7-0.20.40.50.60.60.3-0.40.40.40.4-0.4-0.4-0.30.3-0.7
Patch foraging water rate 12 sec0.40.91.5-0.0-0.50.51.2-0.9-1.1-0.80.91.01.01.01.0-1.00.91.00.9-1.0-1.2-1.01.1-1.2
Patch foraging water rate 18 sec0.71.02.8-0.2-0.30.41.2-0.9-1.2-0.81.01.01.11.11.0-1.01.01.01.0-0.9-1.4-1.01.1-1.7
Patch foraging water rate 24 sec0.00.10.5-0.50.2-0.10.2-0.0-0.0-0.10.10.1-0.0-0.00.1-0.10.10.20.1-0.2-0.6-0.20.3-0.7
Patch foraging water rate 6 sec0.91.32.10.9-1.41.31.4-1.2-1.0-1.21.11.31.01.01.1-1.11.11.11.1-1.1-1.3-1.21.3-0.5
Seeking ratio, delayed vs. immediate footshock3.13.85.22.3-2.02.11.9-2.1-2.0-2.02.12.11.81.82.1-1.91.82.11.9-2.0-1.9-1.61.81.3
Distance traveled before self-admin0.60.72.00.8-1.31.40.9-0.8-0.5-1.00.80.80.60.60.7-0.80.80.80.8-0.7-0.8-0.90.90.5
Distance traveled after self-admin0.10.20.70.40.2-0.2-0.20.40.40.4-0.4-0.3-0.7-0.7-0.20.5-0.5-0.3-0.40.20.10.6-0.30.8
Extensor digitorum longus weight0.20.63.60.50.1-0.4-1.00.50.70.4-0.5-0.8-0.6-0.6-0.70.6-0.7-0.8-0.50.70.70.8-0.91.9
Bone: elastic displacement7.58.610.12.1-2.82.83.1-3.1-3.2-3.03.13.13.03.03.1-3.03.03.13.0-3.1-2.8-2.92.9-1.9
Bone: elastic work3.64.86.10.6-1.71.82.3-2.3-2.5-2.12.32.22.42.42.4-2.32.32.42.3-2.4-2.3-2.22.4-1.2
Bone: endosteal estimation0.81.73.5-1.41.9-1.9-1.61.31.01.5-1.3-1.5-1.1-1.1-1.01.3-1.3-1.3-1.21.11.01.5-1.20.1
Bone: endosteal perimeter0.10.10.4-0.20.6-0.7-0.50.30.10.4-0.3-0.5-0.1-0.1-0.10.3-0.3-0.3-0.30.20.30.5-0.4-0.5
Epididymis fat weight0.31.03.4-0.51.7-1.8-0.91.00.41.3-0.9-0.9-0.6-0.6-0.91.1-1.1-0.8-1.00.70.71.4-1.1-0.5
Delta time in closed arm before/after self-admin0.10.10.50.5-0.40.50.1-0.20.1-0.30.10.0-0.1-0.1-0.0-0.10.1-0.00.10.1-0.0-0.2-0.0-0.7
Delta time in open arm before/after self-admin0.30.30.7-0.0-0.20.10.8-0.5-0.6-0.40.50.80.80.80.5-0.50.50.60.5-0.5-0.5-0.60.50.2
Diff in mean of infusions in LGA sessions0.40.50.80.20.2-0.3-0.50.70.80.6-0.7-0.5-0.8-0.8-0.90.8-0.8-0.8-0.80.90.90.7-0.80.5
Delay discount exponential model param0.20.20.8-0.7-0.20.4-0.1-0.3-0.3-0.40.40.00.30.30.7-0.50.50.40.5-0.6-0.9-0.50.80.3
Extinction: sum of active levers before priming3.03.36.92.6-1.81.72.0-1.8-1.9-1.61.82.01.81.81.8-1.61.61.81.6-1.8-1.7-1.31.4-2.3
Active lever presses in extinction session 60.40.45.32.3-1.30.80.6-0.10.3-0.2-0.00.4-0.5-0.5-0.10.2-0.20.0-0.20.1-0.00.2-0.20.1
Bone: final force2.03.26.4-2.42.5-2.5-2.01.91.42.0-1.8-2.0-1.5-1.5-1.61.7-1.7-1.7-1.61.61.21.9-1.50.6
Bone: final moment1.72.75.6-2.32.4-2.4-1.91.71.31.9-1.6-1.8-1.3-1.3-1.41.6-1.6-1.5-1.51.41.01.7-1.30.3
Food consumed during 24 hour testing period0.10.11.3-1.10.2-0.2-0.10.10.10.0-0.0-0.20.10.1-0.0-0.10.1-0.00.1-0.1-0.2-0.20.30.7
Glucose0.10.11.4-1.20.4-0.40.20.1-0.10.1-0.10.40.20.2-0.1-0.10.10.10.00.0-0.3-0.20.2-0.0
Heart weight1.72.65.5-2.31.8-1.8-1.81.71.61.7-1.6-1.9-1.5-1.5-1.51.5-1.5-1.7-1.51.61.51.3-1.30.0
Delay discount hyperbolic model param0.20.20.7-0.7-0.10.3-0.1-0.2-0.3-0.30.30.00.30.30.7-0.40.40.40.5-0.6-0.8-0.50.80.1
Intermittent access intake day 1-15 change0.20.50.9-0.10.8-0.8-0.00.70.60.8-0.7-0.1-0.8-0.8-0.80.8-0.8-0.5-0.80.81.00.7-0.90.2
Intermittent access intake escalation0.20.40.70.00.8-0.70.10.50.40.7-0.60.0-0.6-0.6-0.70.7-0.7-0.4-0.70.60.90.7-0.80.0
Intermittent access intake escalation 20.10.10.60.8-0.20.20.6-0.4-0.5-0.20.30.60.30.30.2-0.20.20.40.2-0.2-0.1-0.10.0-0.5
Intermitt. access day 1 inactive lever presses0.10.42.2-1.50.7-0.8-1.00.60.50.5-0.5-1.0-0.5-0.5-0.50.4-0.4-0.6-0.30.40.60.3-0.3-0.7
Intermitt. access day 15 inactive lever presses2.34.733.1-5.83.6-3.3-2.32.01.32.0-1.7-2.4-1.1-1.1-1.11.3-1.3-1.7-1.31.21.21.1-0.61.2
Intermitt. access escalation Index0.71.01.40.6-1.21.10.8-1.0-0.9-1.11.00.80.80.81.2-1.11.11.01.1-1.1-1.1-1.11.2-0.5
Intermittent access day 1 total infusions0.20.40.5-0.70.00.10.7-0.5-0.7-0.50.60.60.70.70.7-0.60.60.60.6-0.7-0.6-0.60.7-0.0
Intermittent access day 15 total infusions0.10.10.8-0.80.9-0.70.30.2-0.00.4-0.20.2-0.2-0.2-0.20.2-0.2-0.0-0.20.10.50.2-0.30.2
Intermittent access terminal intake (last 3 days)0.10.20.7-0.80.9-0.80.10.30.10.5-0.30.0-0.2-0.2-0.30.3-0.3-0.2-0.30.20.70.3-0.40.2
Intermittent access total infusions0.10.20.6-0.80.7-0.60.5-0.2-0.60.00.20.40.40.40.3-0.20.20.40.2-0.4-0.1-0.10.1-0.0
Intermittent access day 1 locomotion0.10.10.5-0.30.7-0.60.20.1-0.10.3-0.10.0-0.0-0.0-0.10.2-0.2-0.0-0.20.10.20.3-0.2-0.6
Intermittent access day 15 total locomotion0.00.10.5-0.70.4-0.50.40.1-0.00.2-0.10.2-0.0-0.0-0.10.1-0.10.1-0.10.00.00.10.0-0.3
Intermittent access total locomotion0.20.20.8-0.70.9-0.80.10.40.10.5-0.3-0.0-0.2-0.2-0.40.4-0.4-0.2-0.40.30.50.4-0.4-0.3
Intermittent access standard deviation0.20.50.8-0.40.9-0.9-0.40.70.60.8-0.7-0.6-0.6-0.6-0.70.7-0.7-0.7-0.70.80.80.8-0.80.8
Left kidney weight1.25.47.7-2.52.8-2.8-2.82.42.12.5-2.3-2.6-2.1-2.1-2.32.3-2.3-2.4-2.22.22.22.3-2.21.0
Right kidney weight1.35.710.4-2.52.7-2.7-3.22.42.22.5-2.4-3.0-2.2-2.2-2.12.3-2.3-2.5-2.22.02.32.4-2.11.1
Cocaine induced anxiety0.10.10.30.20.3-0.3-0.30.1-0.00.2-0.1-0.50.00.0-0.20.2-0.2-0.3-0.10.20.30.4-0.4-0.6
Post-drug Anxiety2.42.54.1-0.31.1-1.1-1.91.51.61.4-1.5-2.0-1.7-1.7-1.71.6-1.6-1.9-1.61.72.01.7-1.80.6
Baseline Anxiety2.42.84.8-0.71.2-1.3-2.21.61.71.5-1.6-2.2-2.0-2.0-1.61.7-1.7-1.9-1.61.51.91.8-1.71.3
Tail length0.93.75.1-0.81.9-2.2-1.91.91.72.1-1.9-1.9-1.9-1.9-2.02.0-2.0-2.0-2.01.92.32.1-2.20.5
Length with tail1.35.77.9-0.52.1-2.5-2.62.42.22.5-2.4-2.6-2.3-2.3-2.42.6-2.6-2.5-2.52.42.72.7-2.80.4
Length without tail1.03.34.4-0.71.7-1.9-1.91.91.82.0-1.9-2.0-1.8-1.8-1.82.0-2.0-1.9-2.01.91.82.1-2.0-0.1
Times rat made contact with spout0.20.20.6-0.7-0.20.20.2-0.4-0.4-0.40.40.20.60.60.3-0.50.50.30.6-0.5-0.3-0.60.60.8
Lifetime Intake0.10.10.4-0.50.6-0.60.5-0.1-0.50.10.20.30.40.40.2-0.20.20.30.2-0.30.10.00.1-0.1
Liver weight, left0.10.10.4-0.20.4-0.6-0.50.30.10.5-0.3-0.2-0.0-0.0-0.40.3-0.4-0.3-0.30.3-0.00.5-0.30.5
Liver weight, right0.20.32.0-1.11.4-1.20.00.3-0.20.6-0.20.00.10.1-0.20.2-0.30.0-0.20.0-0.00.5-0.3-0.1
Locomotor activity0.10.21.30.2-1.20.80.4-0.30.0-0.50.30.20.20.20.2-0.40.40.30.4-0.2-0.4-0.70.60.3
Locomotor testing distance0.20.42.10.8-1.51.20.9-0.40.0-0.70.30.70.10.10.3-0.40.40.50.3-0.2-0.5-0.80.70.7
Locomotor testing rearing0.81.54.42.0-2.12.01.3-1.2-0.7-1.41.11.11.01.00.9-1.11.11.01.0-0.9-1.0-1.21.0-0.0
Locomotion in novel chamber0.00.00.1-0.2-0.0-0.1-0.4-0.0-0.1-0.00.1-0.20.00.00.2-0.10.10.00.1-0.1-0.1-0.10.2-0.0
Locomotion in novel chamber post-restriction0.10.12.01.4-0.60.40.1-0.2-0.2-0.20.20.1-0.0-0.00.3-0.00.00.20.1-0.2-0.10.1-0.0-0.4
Fecal boli incidents, locomotor time 10.20.32.3-1.10.3-0.40.1-0.2-0.4-0.20.30.10.70.70.4-0.40.40.30.4-0.4-0.4-0.30.51.5
Change in fecal boli incidents, locomotor task1.71.712.03.5-1.51.61.5-1.3-1.2-1.11.21.51.11.10.6-0.80.80.90.8-0.5-0.4-0.50.0-1.5
Time >=10cm from walls, locomotor time 10.10.22.31.5-0.50.30.1-0.3-0.3-0.20.20.1-0.1-0.10.1-0.10.00.20.1-0.1-0.10.2-0.20.4
Bouts of movement, locomotor time 10.40.52.4-1.60.8-0.9-0.80.70.70.7-0.7-0.7-0.6-0.6-0.70.5-0.5-0.7-0.50.50.60.4-0.40.3
Total resting periods, locomotor time 10.40.51.9-1.40.7-0.8-0.70.70.70.6-0.6-0.6-0.5-0.5-0.70.5-0.5-0.6-0.50.60.60.4-0.40.7
Rest time, locomotor task time 10.20.22.5-1.60.6-0.5-0.50.40.30.4-0.3-0.4-0.1-0.1-0.40.2-0.2-0.4-0.20.50.30.1-0.10.3
Distance moved, locomotor task time 11.01.54.12.0-1.31.31.3-1.4-1.4-1.21.31.31.31.31.2-1.11.11.31.1-1.2-1.0-0.80.80.2
Vertical activity count, locomotor time 10.20.63.71.90.0-0.3-0.50.40.30.6-0.4-0.5-0.9-0.9-0.50.7-0.8-0.6-0.70.40.61.1-0.9-0.7
Time >=10cm from walls, locomotor time 20.71.11.70.8-0.70.71.0-1.1-1.3-1.01.20.91.11.11.2-1.01.01.21.1-1.2-1.3-0.81.1-0.3
Bouts of movement, locomotor time 20.50.81.30.20.7-0.7-0.80.90.90.9-0.9-0.7-1.0-1.0-0.91.0-1.0-0.9-1.00.91.11.1-1.11.0
Total resting periods, locomotor time 20.30.61.00.10.7-0.6-0.60.70.70.8-0.8-0.6-0.9-0.9-0.80.9-0.9-0.7-0.90.81.01.0-0.90.6
Rest time, locomotor task time 20.60.71.0-0.80.9-0.7-0.71.01.00.9-1.0-0.7-0.9-0.9-0.80.9-0.9-0.9-1.01.00.50.8-0.7-0.2
Distance moved, locomotor task time 20.80.91.50.3-0.70.70.7-1.0-1.1-1.01.10.91.11.11.2-1.01.01.11.1-1.2-0.9-0.81.00.9
Vertical activity count, locomotor time 20.20.30.90.70.3-0.5-0.90.40.30.5-0.4-0.9-0.7-0.7-0.20.6-0.6-0.5-0.50.10.50.9-0.60.4
Light reinforcement 10.30.81.6-1.3-0.30.50.5-0.8-0.9-0.90.90.60.90.91.1-1.11.10.81.1-1.0-0.7-1.11.2-0.2
Light reinforcement 20.40.61.0-0.3-0.30.50.7-0.8-0.9-0.70.80.70.70.71.0-0.90.90.80.9-0.9-0.7-0.80.9-0.6
Bone: marrow area0.71.53.2-1.31.8-1.8-1.51.20.91.4-1.2-1.5-1.0-1.0-1.01.2-1.2-1.2-1.11.10.91.4-1.20.0
Bone: maximum diameter0.10.32.5-1.20.6-0.6-0.60.30.10.4-0.3-0.5-0.0-0.0-0.00.2-0.2-0.1-0.10.1-0.20.20.1-1.6
Bone: maximum force1.11.95.0-2.22.0-2.0-1.61.41.01.6-1.3-1.6-1.1-1.1-1.11.3-1.3-1.3-1.21.10.71.4-0.9-0.1
Bone: maximum moment0.81.54.5-2.11.8-1.8-1.41.20.81.4-1.1-1.4-0.9-0.9-0.91.1-1.1-1.1-1.00.90.51.2-0.7-0.5
Mean time between licks in bursts0.00.00.6-0.10.4-0.20.0-0.0-0.20.10.00.10.00.00.10.1-0.10.1-0.0-0.20.00.2-0.00.8
Mean num. licks in bursts0.00.00.2-0.40.3-0.30.0-0.0-0.20.10.0-0.10.20.2-0.1-0.00.0-0.00.0-0.00.30.00.0-0.1
Cd content in liver0.10.11.7-0.4-0.30.20.4-0.10.0-0.30.10.40.10.10.1-0.30.30.20.2-0.10.1-0.50.21.3
Co content in liver2.42.83.70.7-1.81.91.7-1.7-1.6-1.81.71.71.71.71.7-1.81.81.81.8-1.7-1.5-1.91.9-0.2
Cu content in liver0.10.10.5-0.1-0.30.1-0.30.20.50.1-0.3-0.4-0.3-0.3-0.40.2-0.2-0.3-0.30.4-0.10.10.10.7
Fe content in liver0.40.50.80.6-0.80.80.8-0.7-0.6-0.70.70.80.60.60.6-0.60.60.70.6-0.6-0.7-0.70.8-0.9
K content in liver0.30.30.5-0.00.4-0.3-0.40.50.60.5-0.6-0.4-0.7-0.7-0.60.6-0.6-0.5-0.60.60.60.6-0.4-0.0
Mg content in liver0.10.10.40.6-0.30.30.00.10.30.1-0.2-0.0-0.3-0.3-0.30.2-0.2-0.2-0.30.30.10.2-0.10.4
Mn content in liver3.03.34.82.2-2.02.22.2-1.9-1.8-1.91.92.11.81.81.7-1.71.71.91.7-1.7-1.6-1.71.5-0.0
Na content in liver0.20.20.5-0.30.7-0.6-0.10.50.40.6-0.5-0.1-0.5-0.5-0.50.6-0.6-0.3-0.60.50.30.6-0.5-0.1
Rb content in liver0.50.63.11.6-0.90.80.5-0.8-0.7-0.70.70.50.60.60.6-0.50.50.50.6-0.6-0.6-0.20.41.8
Se content in liver0.80.94.00.7-0.81.11.3-0.8-0.8-0.80.81.30.70.70.7-0.80.91.00.8-0.7-0.8-1.00.7-2.0
Sr content in liver0.00.00.10.00.3-0.10.10.10.00.1-0.10.1-0.1-0.1-0.10.1-0.10.0-0.10.10.10.1-0.1-0.1
Zn content in liver0.20.20.7-0.80.2-0.3-0.40.50.60.3-0.4-0.5-0.5-0.5-0.50.3-0.3-0.4-0.40.50.30.2-0.10.3
Bone: minimum diameter0.20.51.8-1.31.0-1.0-0.60.70.40.9-0.6-0.6-0.4-0.4-0.50.6-0.6-0.5-0.60.50.30.7-0.4-0.6
Time in familiar zone, hab. session 10.50.51.5-0.90.9-0.9-0.90.70.60.7-0.6-0.9-0.6-0.6-0.40.6-0.6-0.6-0.60.40.10.6-0.4-1.2
Time in novel zone, hab. session 10.10.11.80.3-0.20.40.5-0.2-0.1-0.20.10.50.10.1-0.1-0.10.10.20.00.00.4-0.1-0.11.3
Total zone transitions, hab. session 10.10.21.6-0.30.4-0.1-0.10.40.50.3-0.4-0.2-0.5-0.5-0.40.4-0.4-0.3-0.40.40.30.3-0.31.3
Total locomotion distance, hab. session 10.30.41.1-0.91.0-0.7-0.40.70.60.6-0.7-0.4-0.7-0.7-0.60.6-0.6-0.5-0.70.60.60.5-0.50.0
Locomotion velocity, hab. session 10.20.30.9-0.70.9-0.7-0.50.60.60.6-0.6-0.4-0.6-0.6-0.60.6-0.6-0.5-0.60.50.50.5-0.50.1
Time in familiar zone, hab. session 20.10.10.6-0.30.6-0.4-0.30.1-0.10.2-0.0-0.60.00.00.00.1-0.1-0.2-0.0-0.00.10.3-0.2-0.7
Time in novel zone, hab. session 20.30.31.8-0.70.1-0.2-0.30.60.80.4-0.6-0.1-0.6-0.6-0.70.4-0.4-0.4-0.50.60.30.1-0.21.3
Total zone transitions, hab. session 20.30.40.7-0.80.8-0.6-0.40.70.70.7-0.7-0.3-0.7-0.7-0.60.6-0.6-0.4-0.70.50.70.5-0.50.8
Total locomotion distance, hab. session 20.60.82.6-1.61.3-1.1-0.80.90.90.9-0.9-0.7-0.8-0.8-0.70.8-0.8-0.7-0.80.70.70.7-0.50.5
Locomotion velocity, hab. session 20.40.52.4-1.61.3-1.0-0.60.70.60.8-0.7-0.4-0.6-0.6-0.50.6-0.6-0.4-0.60.40.50.5-0.30.3
Novel to familiar place preference ratio0.50.50.80.7-0.70.70.7-0.8-0.9-0.70.80.80.90.90.6-0.70.70.70.7-0.6-0.8-0.60.6-0.6
Novelty place preference1.11.11.60.4-0.80.81.1-1.1-1.2-1.01.11.21.21.21.0-1.11.11.11.1-1.0-1.2-1.01.1-1.0
Time in novel zone, NPP test1.31.42.00.4-0.80.91.3-1.2-1.4-1.11.21.41.41.41.1-1.21.21.31.2-1.2-1.4-1.21.2-1.2
Total zone transitions, NPP test0.10.10.80.9-0.50.60.7-0.2-0.0-0.30.10.8-0.1-0.10.0-0.10.10.40.1-0.2-0.0-0.30.10.0
Total locomotion distance, NPP test0.10.10.7-0.3-0.10.30.6-0.2-0.1-0.30.20.60.10.10.2-0.30.30.40.2-0.3-0.3-0.50.4-0.9
Locomotion velocity, NPP test0.00.10.3-0.30.20.00.20.20.40.1-0.20.2-0.3-0.3-0.20.1-0.10.0-0.20.20.1-0.1-0.0-0.6
Intraocular pressure1.01.43.50.9-1.91.71.5-1.1-0.7-1.31.01.60.90.91.0-1.21.21.21.0-1.0-1.0-1.51.2-0.2
Delta distance traveled before/after self-admin1.71.83.2-0.81.7-1.8-1.51.41.21.6-1.4-1.5-1.4-1.4-1.11.4-1.4-1.3-1.41.11.11.6-1.30.5
Delta ambulatory time before/after self-admin1.62.03.2-1.01.8-1.8-1.61.51.21.6-1.4-1.6-1.5-1.5-1.11.5-1.5-1.4-1.41.11.11.6-1.30.3
Parametrial fat weight1.63.75.4-1.21.8-2.1-2.32.01.82.1-1.9-2.3-1.9-1.9-1.92.0-2.0-2.0-2.01.81.52.2-1.91.7
Pavlov. Cond. lever latency1.92.43.11.8-1.41.41.5-1.7-1.8-1.51.71.41.71.71.6-1.51.51.51.6-1.6-1.5-1.21.2-1.5
Pavlov. Cond. magazine entry latency7.09.013.0-1.12.3-2.5-3.03.13.33.0-3.1-2.8-3.2-3.2-3.33.2-3.1-3.1-3.23.23.63.0-3.32.9
Pavlov. Cond. change in total contacts3.13.35.0-1.31.3-1.4-1.42.02.21.8-2.0-1.4-2.1-2.1-2.11.9-1.9-1.8-2.02.21.71.5-1.71.5
Pavlov. Cond. index score6.17.79.9-1.32.1-2.3-2.82.93.12.7-2.9-2.6-3.1-3.1-3.02.9-2.9-2.8-2.93.03.12.7-2.92.4
Pavlov. Cond. latency score4.25.47.1-1.21.8-1.9-2.32.42.62.3-2.5-2.1-2.6-2.6-2.52.4-2.4-2.4-2.42.52.72.2-2.32.1
Pavlov. Cond. lever contacts3.03.54.6-1.51.6-1.7-1.92.02.11.9-2.0-1.7-2.1-2.1-2.01.9-1.9-1.9-2.02.02.11.7-1.71.5
Pavlov. Cond. magazine entry number5.56.98.91.0-1.82.02.7-2.7-3.0-2.52.82.52.92.92.9-2.82.72.72.8-2.8-3.0-2.62.7-2.4
Pavlov. Cond. intertrial magazine entries1.11.33.3-1.8-0.30.50.8-0.8-0.9-1.00.90.81.11.11.2-1.31.31.01.2-1.1-1.6-1.61.8-0.9
Pavlov. Cond. lever-magazine prob. diff.6.68.210.6-1.32.2-2.3-2.83.03.22.8-3.0-2.7-3.2-3.2-3.13.0-3.0-3.0-3.13.13.32.8-3.02.3
Pavlov. Cond. response bias6.07.49.4-1.92.2-2.3-2.82.93.12.7-2.9-2.7-3.0-3.0-2.92.8-2.8-2.8-2.82.82.92.5-2.62.6
Pavlov. Cond. lever latency0.10.21.31.1-0.60.50.4-0.5-0.5-0.40.40.30.40.40.4-0.30.30.40.3-0.4-0.1-0.10.20.1
Pavlov. Cond. magazine entry latency0.30.41.5-1.21.2-1.0-0.50.60.40.7-0.6-0.3-0.4-0.4-0.50.5-0.5-0.4-0.50.40.50.6-0.40.0
Pavlov. Cond. change in total contacts1.01.62.4-0.20.9-0.9-1.11.31.51.3-1.4-1.0-1.5-1.5-1.51.4-1.4-1.4-1.51.51.31.3-1.5-0.3
Pavlov. Cond. index score0.10.10.9-0.90.6-0.5-0.30.30.30.3-0.3-0.0-0.3-0.3-0.30.2-0.2-0.2-0.30.20.10.1-0.1-0.2
Pavlov. Cond. latency score0.10.10.5-0.70.6-0.5-0.20.30.30.4-0.30.0-0.3-0.3-0.30.3-0.3-0.2-0.30.20.20.2-0.2-0.4
Pavlov. Cond. lever contacts0.00.10.9-0.90.4-0.3-0.20.20.20.1-0.1-0.0-0.1-0.1-0.10.0-0.0-0.1-0.00.1-0.1-0.10.1-0.1
Pavlov. Cond. magazine entry number1.21.53.01.7-1.51.41.2-1.3-1.3-1.31.31.11.21.21.3-1.21.21.21.2-1.2-1.1-1.01.00.1
Pavlov. Cond. intertrial magazine entries1.21.92.50.3-1.01.01.3-1.5-1.6-1.41.51.31.51.51.6-1.51.51.51.5-1.5-1.2-1.41.4-0.9
Pavlov. Cond. lever-magazine prob. diff.0.10.11.1-1.00.6-0.5-0.30.40.30.3-0.3-0.1-0.3-0.3-0.30.2-0.2-0.2-0.30.20.10.1-0.1-0.1
Pavlov. Cond. response bias0.50.71.8-1.31.1-0.9-0.90.90.90.8-0.9-0.7-0.8-0.8-0.80.8-0.8-0.8-0.80.80.60.6-0.70.3
Time in closed arm before self-admin0.10.10.60.8-0.3-0.00.3-0.2-0.4-0.10.30.50.10.10.3-0.10.10.50.2-0.4-0.30.10.1-0.0
Time in closed arm after self-admin0.40.43.71.9-1.00.50.6-0.5-0.4-0.40.40.6-0.0-0.00.4-0.20.20.40.2-0.3-0.4-0.1-0.0-1.0
Time in open arm before self-admin0.50.51.4-1.20.8-0.5-1.00.70.70.7-0.7-0.9-0.6-0.6-0.50.6-0.6-0.8-0.60.60.60.5-0.40.9
Time in open arm after self-admin0.70.81.50.3-0.40.80.8-0.9-1.1-0.81.00.91.21.21.0-0.90.91.00.9-1.0-1.0-0.81.00.5
Bone: periosteal estimation0.10.31.7-1.30.9-1.0-0.60.40.10.6-0.3-0.6-0.1-0.1-0.00.3-0.3-0.3-0.20.1-0.20.4-0.1-0.6
Bone: periosteal perimeter0.10.10.7-0.80.4-0.5-0.40.1-0.10.2-0.1-0.30.10.10.10.0-0.0-0.00.0-0.0-0.20.10.2-0.8
Bone: post-yield work1.31.93.1-1.51.7-1.8-1.31.51.31.6-1.5-1.2-1.4-1.4-1.31.4-1.4-1.2-1.41.41.21.3-1.2-0.7
Progressive ratio test 1 active lever presses1.82.22.8-0.71.4-1.4-1.11.51.51.5-1.5-1.3-1.5-1.5-1.61.6-1.6-1.5-1.61.61.71.6-1.61.4
Progressive ratio test 1 breakpoint2.02.43.0-0.71.5-1.5-1.21.61.61.6-1.6-1.4-1.6-1.6-1.61.7-1.7-1.6-1.71.71.71.7-1.71.4
Progressive ratio test 1 inactive lever presses0.40.61.7-1.01.3-1.3-0.80.70.50.9-0.7-0.9-0.5-0.5-0.50.7-0.8-0.7-0.70.60.70.9-0.70.5
Progressive ratio test 2 active lever presses0.30.30.7-0.20.7-0.8-0.30.50.30.7-0.5-0.4-0.4-0.4-0.80.6-0.6-0.6-0.60.60.80.8-0.8-0.2
Progressive ratio test 2 breakpoint0.30.30.7-0.20.7-0.8-0.30.50.20.6-0.4-0.4-0.3-0.3-0.70.5-0.5-0.5-0.50.50.70.7-0.7-0.1
Progressive ratio test 2 inactive lever presses0.50.87.0-2.71.4-1.3-0.1-0.2-0.90.10.4-0.10.80.80.7-0.50.50.40.6-0.8-0.7-0.30.9-0.2
Incentive Sensitization - Responses0.20.21.40.6-0.20.10.4-0.5-0.7-0.30.50.30.40.40.3-0.40.40.40.4-0.5-0.4-0.20.3-1.2
Incentive Sensitization - Breakpoint0.30.41.90.6-0.40.30.6-0.7-0.9-0.50.70.50.70.70.5-0.60.60.60.6-0.7-0.6-0.40.5-1.4
Sum of active levers in priming session hrs 5-60.20.20.80.9-0.30.10.20.20.40.2-0.30.2-0.5-0.5-0.30.4-0.4-0.2-0.50.30.10.4-0.30.6
Progressive ratio0.30.42.6-1.60.1-0.10.9-0.3-0.4-0.30.30.80.50.50.5-0.60.60.70.5-0.5-0.3-0.80.70.3
Food seeking constrained by brief footshock0.40.54.5-2.10.5-0.5-0.2-0.2-0.5-0.20.3-0.30.40.40.8-0.50.50.40.6-0.8-0.8-0.50.9-0.0
Seeking ratio, punishment vs. effort0.10.21.00.5-0.10.1-0.6-0.3-0.3-0.20.3-0.50.20.20.4-0.20.10.00.3-0.4-0.60.10.3-1.0
Retroperitoneal fat weight0.20.76.3-2.51.5-1.5-0.90.80.30.9-0.6-0.8-0.3-0.3-0.20.4-0.4-0.4-0.40.1-0.10.40.0-0.4
Reaction time number correct0.10.10.8-0.9-0.10.10.4-0.1-0.1-0.20.10.40.10.10.1-0.30.30.20.2-0.2-0.3-0.50.4-0.9
Reaction time mean minus median0.92.13.41.8-1.71.81.7-1.5-1.3-1.61.41.81.41.41.2-1.41.41.41.4-1.1-1.1-1.51.0-1.2
Reaction time mean minus median AUC0.51.45.22.3-1.81.81.3-1.1-0.7-1.21.01.40.90.90.6-0.90.90.80.8-0.5-0.6-1.10.5-1.5
Reaction time num false alarms0.00.10.3-0.2-0.50.5-0.1-0.10.2-0.30.0-0.10.10.10.1-0.20.20.00.2-0.10.2-0.40.30.3
Reaction time num false alarms AUC0.00.10.2-0.5-0.30.3-0.20.20.4-0.1-0.2-0.2-0.1-0.1-0.2-0.00.0-0.2-0.00.20.4-0.30.10.3
Reaction time trials correct on left0.10.10.8-0.9-0.10.10.4-0.1-0.1-0.20.10.40.10.10.1-0.30.30.20.2-0.2-0.3-0.50.4-0.9
Reaction time trials on left0.10.20.8-0.9-0.20.10.5-0.1-0.1-0.20.10.40.10.10.2-0.30.30.30.2-0.2-0.3-0.60.5-0.9
Reaction time mean0.10.11.41.2-0.50.6-0.1-0.00.2-0.1-0.00.1-0.1-0.1-0.10.1-0.1-0.1-0.10.20.10.1-0.20.3
Reaction time mean AUC0.10.22.21.5-0.70.70.1-0.20.1-0.30.10.40.00.0-0.00.00.00.1-0.00.1-0.00.0-0.20.1
Median of all reaction times0.40.61.10.40.3-0.3-0.90.70.90.6-0.8-0.6-0.8-0.8-0.70.8-0.8-0.8-0.80.80.60.8-0.81.0
Reaction time omissions0.71.12.2-0.5-0.91.00.7-0.9-0.7-1.10.90.90.90.91.2-1.11.11.01.1-1.1-1.3-1.31.51.2
Reaction time false alarm rate0.10.10.60.1-0.30.2-0.50.30.50.1-0.3-0.5-0.2-0.2-0.30.3-0.3-0.4-0.30.30.60.2-0.30.8
Reaction time premature initiation rate1.31.85.02.2-1.41.51.6-1.5-1.4-1.41.41.51.31.31.0-1.21.21.31.2-1.0-1.3-1.10.9-0.6
Reaction time premature initiations1.01.73.01.7-1.41.51.7-1.4-1.3-1.41.31.51.21.21.0-1.21.21.31.2-1.0-1.3-1.21.0-0.7
Std. dev. reaction times0.61.22.11.2-1.31.41.2-1.1-0.9-1.21.11.31.11.11.0-1.11.11.01.0-0.8-1.0-1.20.9-0.7
Reaction time trials completed0.10.20.8-0.9-0.20.10.5-0.1-0.1-0.20.10.40.10.10.2-0.30.30.30.2-0.2-0.3-0.60.5-0.9
Reaction time trials AUC0.00.11.0-1.0-0.1-0.00.30.00.1-0.1-0.00.2-0.0-0.00.0-0.20.20.10.1-0.1-0.2-0.40.4-0.6
Run reversals in cocaine runway, females0.20.20.70.80.1-0.1-0.20.30.30.3-0.3-0.2-0.4-0.4-0.50.4-0.4-0.3-0.50.50.40.5-0.6-0.6
Run reversals in cocaine runway, males0.20.21.1-1.00.1-0.00.00.30.50.1-0.3-0.0-0.5-0.5-0.10.1-0.1-0.1-0.20.2-0.2-0.20.2-0.9
Latency to leave start box in cocaine runway2.02.23.50.8-1.51.61.2-1.5-1.4-1.51.51.11.51.51.8-1.51.51.51.5-1.8-1.9-1.51.8-0.9
Latency to leave start box in cocaine runway, F0.70.81.7-0.0-0.60.70.4-0.9-0.9-0.80.90.31.11.11.2-0.90.90.90.9-1.1-1.3-0.81.3-0.6
Latency to leave start box in cocaine runway, M1.91.73.01.3-1.71.71.3-1.3-1.1-1.51.31.31.11.11.4-1.31.31.31.3-1.4-1.3-1.31.4-0.6
Std. dev. time between licks in bursts1.31.82.80.1-0.91.01.3-1.4-1.5-1.31.41.41.51.51.4-1.51.51.51.5-1.6-1.7-1.41.5-0.3
Total sessions with >9 infusions0.20.31.3-0.61.1-1.1-0.20.40.10.7-0.4-0.5-0.1-0.1-0.30.4-0.4-0.3-0.40.30.60.6-0.6-0.5
Short access day 1 total inactive lever presses1.21.512.7-3.62.1-2.0-0.91.10.61.2-1.0-1.0-0.7-0.7-0.80.7-0.7-0.8-0.70.70.90.5-0.3-0.4
Short access day 10 total inactive lever presses0.10.20.8-0.60.5-0.5-0.90.20.10.3-0.1-0.9-0.0-0.0-0.10.2-0.2-0.4-0.10.10.10.3-0.1-0.9
Short access day 1 total infusions0.10.20.4-0.20.5-0.6-0.20.40.30.4-0.4-0.4-0.3-0.3-0.50.4-0.4-0.4-0.40.40.60.4-0.5-0.5
Short access day 10 total infusions0.20.31.0-0.91.0-0.8-0.00.50.30.6-0.4-0.0-0.3-0.3-0.30.4-0.4-0.3-0.40.40.40.5-0.40.8
Short access total infusions0.00.10.2-0.30.4-0.40.5-0.1-0.30.10.10.30.30.30.2-0.10.10.30.1-0.20.1-0.00.0-0.2
Short access day 1 locomotion0.20.30.9-0.41.0-0.70.00.40.20.5-0.4-0.2-0.1-0.1-0.60.4-0.4-0.4-0.40.50.90.6-0.80.4
Short access day 10 total locomotion1.32.44.1-1.22.0-1.9-1.31.61.41.7-1.6-1.4-1.5-1.5-1.61.6-1.6-1.5-1.61.61.81.7-1.70.2
Short access total locomotion0.40.41.8-0.81.4-1.2-0.20.60.20.8-0.5-0.4-0.2-0.2-0.50.6-0.6-0.5-0.60.60.80.8-0.8-0.1
One hour access (0.3 mA shock)0.10.10.40.20.6-0.60.50.1-0.30.4-0.10.50.00.0-0.30.3-0.30.1-0.30.20.50.5-0.50.5
Compulsive drug intake0.40.52.41.5-1.11.01.4-0.6-0.5-0.60.51.40.40.40.1-0.40.40.80.3-0.3-0.1-0.50.2-0.0
One hour access (shock baseline)0.20.31.8-1.11.3-1.1-0.30.2-0.30.5-0.1-0.30.10.1-0.00.2-0.2-0.1-0.10.00.10.5-0.20.2
Social response proportion0.20.20.70.7-0.0-0.00.4-0.5-0.8-0.20.50.20.60.60.5-0.30.30.40.4-0.60.1-0.00.1-0.5
Social responses1.72.24.1-0.6-0.50.51.0-1.5-1.9-1.31.60.92.02.01.7-1.71.71.41.8-1.8-1.3-1.51.7-1.4
Social time0.71.02.1-1.40.4-0.20.9-0.8-1.2-0.60.91.11.31.31.1-1.01.01.01.1-1.1-0.9-1.01.1-0.6
Soleus weight4.212.314.9-2.83.8-3.9-3.93.63.43.7-3.6-3.7-3.4-3.4-3.53.6-3.6-3.6-3.53.53.43.7-3.52.0
Bone: stiffness2.13.55.1-1.92.3-2.3-2.22.01.72.1-1.9-2.1-1.7-1.7-1.81.9-1.9-1.9-1.81.71.42.0-1.60.7
Tibialis anterior weight1.34.56.10.21.3-1.6-2.42.12.32.0-2.1-2.3-2.3-2.3-2.32.3-2.3-2.3-2.22.32.32.4-2.51.8
Time to tail flick, vehicle, before self-admin0.20.21.11.1-0.80.3-0.1-0.6-0.5-0.50.6-0.00.60.60.4-0.40.40.20.5-0.4-0.1-0.20.1-0.1
Time to tail flick, vehicle, after self-admin0.30.41.10.9-0.20.2-0.2-0.7-1.0-0.40.7-0.10.80.80.8-0.50.50.40.7-0.7-0.8-0.00.40.2
Time to tail flick, test, before self-admin0.10.11.21.1-0.3-0.2-0.2-0.0-0.00.1-0.0-0.1-0.0-0.0-0.30.2-0.2-0.1-0.10.20.30.4-0.50.8
Time to tail flick, test, after self-admin0.20.21.3-0.81.1-1.2-0.20.2-0.30.5-0.2-0.2-0.1-0.10.20.2-0.2-0.0-0.2-0.1-0.20.5-0.1-0.3
Delta time to tail flick, vehicle, before/after SA0.20.11.8-1.40.7-0.4-0.30.2-0.10.2-0.1-0.3-0.1-0.10.2-0.00.0-0.00.1-0.1-0.4-0.10.4-0.1
Delta time to tail flick, test, before/after SA0.50.54.9-2.21.1-0.7-0.1-0.2-0.6-0.00.3-0.20.40.40.8-0.40.40.40.5-0.8-0.9-0.30.9-0.3
Tibia length3.49.411.33.1-3.43.33.1-3.2-3.0-3.23.13.03.13.12.9-3.03.03.03.0-2.9-3.1-2.92.8-3.0
Ambulatory time before self-admin1.11.72.91.0-1.71.71.4-1.3-1.1-1.41.31.31.11.11.3-1.31.31.41.3-1.3-1.4-1.41.40.0
Ambulatory time after self-admin0.10.10.90.9-0.00.10.3-0.1-0.20.00.10.3-0.1-0.10.40.1-0.10.3-0.0-0.4-0.40.30.10.3
Bone: tissue strength0.20.20.50.4-0.40.50.5-0.5-0.6-0.40.50.40.60.60.5-0.50.40.50.5-0.5-0.4-0.40.4-0.7
Total heroin consumption0.70.81.4-0.60.6-0.8-0.71.11.21.0-1.1-0.8-1.1-1.1-0.81.0-1.0-0.9-1.10.90.80.8-0.80.5
Bone: trabecular number0.91.54.8-0.50.9-1.1-1.11.21.41.2-1.3-0.9-1.3-1.3-1.21.3-1.3-1.1-1.21.31.21.2-1.22.2
Bone: trabecular spacing3.04.010.71.0-1.82.02.1-1.9-1.8-1.91.92.11.81.81.8-1.91.92.01.8-1.8-2.1-2.12.1-3.3
Bone: trabecular thickness0.30.43.6-0.00.3-0.5-0.50.50.50.5-0.5-0.4-0.4-0.4-0.50.5-0.5-0.4-0.50.50.50.7-0.61.9
Bone: trabecular tissue density1.42.13.6-0.10.8-1.0-1.91.51.71.4-1.5-1.9-1.6-1.6-1.51.6-1.6-1.7-1.51.61.11.6-1.50.6
Water consumed over 24 hours0.81.01.6-0.3-1.00.91.0-1.0-0.9-1.11.00.91.21.20.9-1.21.20.91.2-1.0-1.0-1.31.20.6
Number of responses in last shaping day4.85.36.9-2.62.5-2.4-2.12.42.52.3-2.4-2.2-2.3-2.3-2.32.3-2.3-2.3-2.32.42.32.1-2.02.1