Acadl

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression Acadl 0.11 0.05 9.3e-10 0.09 0.11 0.12 0.11 1.6e-07 4.3e-09 4.9e-10 6.8e-09
2 Liver mRNA stability Acadl 0.13 0.06 1.6e-08 0.06 0.06 0.04 0.06 1.1e-07 3.8e-07 1.5e-05 7.6e-07
3 Adipose mRNA stability Acadl 0.25 0.08 0.0e+00 0.18 0.18 0.18 0.18 3.1e-19 6.2e-20 9.4e-20 6.2e-20
4 BLA mRNA stability Acadl 0.07 0.05 5.7e-03 0.05 0.03 0.03 0.03 1.3e-03 7.5e-03 1.4e-02 6.2e-03
5 LHb gene expression Acadl 0.32 0.12 1.4e-06 0.13 0.27 0.24 0.25 5.8e-04 3.9e-07 2.2e-06 1.5e-06
6 NAcc gene expression Acadl 0.1 0.04 0.0e+00 0.13 0.16 0.16 0.16 7.3e-19 5.6e-24 1.2e-23 1.6e-23
7 Liver gene expression Acadl 0.07 0.05 1.4e-04 0.01 0.02 0.02 0.02 7.9e-03 4.9e-03 3.3e-03 2.6e-03
8 BLA gene expression Acadl 0.17 0.07 9.6e-09 0.12 0.14 0.12 0.12 3.9e-07 9.5e-08 6.5e-07 1.1e-06
9 Adipose isoform ratio NM_012819.2 0.04 0.02 3.3e-03 -0 -0 -0 -0 7.2e-01 4.1e-01 5.7e-01 9.2e-01
10 IL gene expression Acadl 0.21 0.11 6.1e-04 0.19 0.13 0.17 0.17 3.0e-05 5.9e-04 6.8e-05 6.9e-05
11 OFC gene expression Acadl 0.34 0.19 1.4e-03 0.09 0.07 -0 0.04 4.5e-03 1.0e-02 3.4e-01 3.1e-02
12 Adipose isoform ratio XM_063266668.1 0.04 0.03 2.8e-03 -0 0 -0 -0 7.8e-01 3.3e-01 5.1e-01 9.6e-01
13 Adipose gene expression Acadl 0.25 0.1 0.0e+00 0.13 0.16 0.14 0.16 5.9e-14 9.2e-18 8.6e-16 3.1e-17
14 PL gene expression Acadl 0.14 0.06 1.7e-16 0.1 0.13 0.11 0.1 2.9e-11 2.0e-14 9.8e-12 2.5e-11
15 Brain gene expression Acadl 0.14 0.06 3.8e-12 0.11 0.14 0.14 0.14 4.3e-10 8.7e-13 7.6e-13 5.1e-13
16 IC gene expression Acadl 0.19 0.08 1.7e-05 0.1 0.11 0.08 0.09 5.9e-05 3.1e-05 2.6e-04 1.5e-04
17 Brain mRNA stability Acadl 0.06 0.03 2.4e-03 -0 0.01 0 -0 4.9e-01 5.4e-02 1.9e-01 7.4e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
Bone: apparent density0.10.11.20.00.10.31.10.30.10.80.2-0.30.00.00.2-0.0-0.2-0.1-0.2-0.3
Area under the delay curve0.20.31.30.3-0.3-0.5-0.50.1-0.2-0.80.1-0.9-0.3-0.30.9-0.10.10.20.5-1.2
BMI with tail1.86.326.6-4.0-5.2-4.4-4.7-2.1-1.62.0-0.0-1.90.30.32.1-0.60.10.2-0.1-1.6
BMI without tail0.61.98.2-1.4-2.9-2.0-2.4-0.4-0.21.40.6-1.41.21.21.50.30.70.60.4-1.0
Body weight0.72.95.31.7-0.50.70.22.31.50.52.1-2.22.12.12.11.62.02.11.5-1.3
Weight adjusted by age0.10.10.3-0.1-0.0-0.1-0.60.20.30.30.5-0.40.10.10.40.40.60.40.5-0.1
Bone surface0.61.02.00.80.20.80.11.31.30.81.4-0.81.21.20.71.31.31.31.1-0.0
Bone volume0.30.52.11.01.01.21.51.10.80.20.7-0.20.40.40.10.60.30.40.3-0.0
Breakpoint value in progressive ratio session1.01.22.70.00.70.30.9-0.9-1.1-0.8-1.41.3-0.9-0.9-1.3-1.4-1.3-1.6-1.60.8
Number of licking bursts0.40.72.0-0.1-0.6-0.3-0.40.70.61.41.1-1.30.70.71.20.70.81.10.7-0.7
Context. condit. distance diff. score0.30.41.0-0.5-0.8-0.50.8-0.3-0.7-0.3-0.5-0.5-0.7-0.70.5-0.7-0.9-0.5-0.4-1.0
Locomotion velocity, session 10.50.62.30.41.21.20.30.00.6-0.4-0.21.40.10.1-1.40.40.3-0.10.11.5
Locomotion distance, session 10.10.10.3-0.4-0.4-0.3-0.1-0.4-0.3-0.4-0.50.3-0.2-0.2-0.3-0.3-0.4-0.4-0.20.0
Locomotion velocity, session 22.63.05.50.9-0.50.5-0.31.92.01.82.3-1.72.32.31.62.12.12.12.0-0.5
Locomotion distance, session 20.10.20.9-0.7-0.9-0.6-1.0-0.30.00.20.1-0.10.50.50.10.10.20.10.20.0
Locomotion velocity, session 32.22.54.9-1.7-0.7-1.20.4-1.9-2.1-0.6-2.00.8-1.7-1.7-0.8-2.1-2.2-2.0-2.0-0.2
Locomotion distance, session 30.60.62.41.01.41.51.30.60.7-0.6-0.10.90.10.1-1.00.3-0.1-0.2-0.00.9
Stereotopy head waving bouts, day 33.33.910.8-3.3-1.7-2.4-2.3-3.1-2.30.6-1.91.3-1.9-1.9-1.1-1.9-1.4-1.7-1.90.9
Stereotopy head waving duration, day 34.04.712.3-3.5-2.0-2.7-1.3-3.1-2.81.4-2.10.8-2.2-2.2-0.7-2.4-2.0-2.0-2.50.2
Locomotion velocity, session 71.41.52.91.5-0.10.60.91.71.3-1.51.0-1.21.41.41.21.20.81.11.7-1.3
Locomotion distance, session 73.13.97.32.40.21.60.72.72.5-1.02.2-1.32.52.51.32.42.12.12.7-0.7
Stereotopy head waving bouts, day 70.10.10.5-0.2-0.3-0.30.2-0.1-0.10.70.0-0.3-0.0-0.00.3-0.1-0.20.0-0.2-0.3
Stereotopy head waving duration, day 71.62.04.1-1.4-1.5-2.00.6-1.1-1.90.1-1.2-1.0-1.2-1.21.1-1.8-1.8-1.1-1.3-2.0
Locomotion velocity, session 80.10.20.9-1.0-0.6-0.7-0.4-0.3-0.20.60.0-0.30.00.00.3-0.0-0.2-0.00.1-0.4
Locomotion distance, session 80.10.10.7-0.3-0.9-0.3-0.20.0-0.0-0.00.1-0.40.30.30.40.0-0.10.00.2-0.5
Degree of sensitization distance1.31.42.50.5-1.1-0.4-0.91.00.9-0.21.3-1.51.41.41.61.11.41.41.6-1.1
Degree of sensitization stereotypy0.60.72.50.6-0.7-0.40.60.80.40.60.7-1.50.70.71.50.40.10.70.6-1.6
Conditioned locomotion0.30.31.10.30.60.50.50.80.61.10.7-0.40.70.70.40.50.40.60.2-0.1
Cocaine response after cond. corrected0.30.31.10.60.91.00.70.10.40.2-0.10.9-0.2-0.2-1.00.2-0.1-0.2-0.11.0
Cocaine response after cond. not corrected0.60.72.51.51.31.61.10.80.9-0.40.30.60.30.3-0.60.60.40.20.40.7
Cocaine response before conditioning1.21.43.01.70.40.70.61.71.2-0.71.3-1.31.21.21.21.11.11.31.4-1.0
Saline control response0.81.13.0-0.6-1.0-0.5-1.60.50.81.71.3-0.81.21.20.81.11.31.30.9-0.0
Bone: connectivity density1.01.63.00.1-1.4-0.5-0.70.90.91.41.5-1.71.41.41.71.21.21.41.3-1.1
Bone: cortical apparent density1.41.99.9-0.7-1.9-1.1-3.2-0.10.80.61.1-0.81.41.40.91.31.81.51.60.1
Bone: cortical area1.32.04.01.20.81.2-0.31.72.00.41.8-0.51.71.70.42.02.01.61.90.4
Bone: cortical porosity2.22.49.71.83.12.83.11.20.80.50.11.3-0.4-0.4-1.50.1-0.3-0.4-0.81.5
Bone: cortical porosity2.52.711.41.93.43.03.11.30.90.60.21.4-0.3-0.3-1.60.2-0.2-0.4-0.91.7
Bone: cortical thickness1.62.75.81.10.20.8-0.71.72.20.42.0-0.82.12.10.82.42.31.92.40.2
Bone: cortical thickness0.20.20.70.60.70.5-0.30.10.5-0.30.10.70.20.2-0.70.40.3-0.00.20.8
Bone: cortical tissue density1.41.910.3-0.8-2.0-1.2-3.2-0.20.70.71.1-0.81.41.40.91.31.81.41.50.0
Condit. Reinf. active minus inactive responses1.01.14.90.21.11.40.00.41.12.20.91.00.40.4-1.11.10.90.50.11.9
Condit. Reinf. active-inactive response ratio0.40.41.7-0.70.40.5-0.1-0.40.11.3-0.00.9-0.4-0.4-1.00.1-0.0-0.3-0.51.2
Condit. Reinf. active responses1.31.63.70.91.41.80.21.11.81.91.40.60.80.8-0.71.61.41.10.81.7
Condit. Reinf. inactive responses0.81.02.11.31.01.20.11.21.50.61.2-0.00.90.9-0.11.41.31.21.10.7
Incentive salience index mean1.11.34.00.71.21.4-0.00.91.62.01.30.50.80.8-0.71.51.31.00.71.6
Condit. Reinf. lever presses0.50.81.51.00.80.8-0.41.01.20.41.1-0.10.80.80.01.21.20.91.00.6
Condit. Reinf. active minus inactive responses2.22.99.72.73.13.02.12.02.0-0.41.10.80.70.7-0.91.51.00.91.01.2
Condit. Reinf. active-inactive response ratio1.72.07.82.32.82.62.71.51.2-0.90.30.8-0.0-0.0-0.90.60.10.20.30.7
Condit. Reinf. active responses1.82.57.22.32.62.71.31.92.0-0.01.30.60.90.9-0.81.71.41.21.21.4
Condit. Reinf. inactive responses0.50.61.50.60.50.7-0.50.71.00.71.00.00.80.8-0.01.01.21.00.80.8
Condit. Reinf. lever presses0.30.41.60.31.20.8-0.2-0.10.3-0.6-0.31.2-0.2-0.2-1.20.10.1-0.2-0.11.3
Condit. Reinf. lever reinforcers received1.82.57.32.52.72.71.61.92.0-0.31.20.60.80.8-0.81.51.21.11.11.2
Conditioned reinforcement - actives0.40.82.9-1.5-0.9-1.7-1.4-1.1-1.00.0-0.5-0.2-0.8-0.80.3-0.7-0.3-0.4-0.4-0.4
Conditioned reinforcement - inactives0.40.62.60.61.60.6-0.60.70.8-0.70.70.1-0.2-0.2-0.10.90.90.81.10.4
Conditioned locomotion3.44.513.4-2.3-2.8-3.7-2.9-2.1-2.4-2.7-1.6-1.2-1.6-1.61.5-1.8-1.1-1.0-0.2-2.5
Patch foraging indifference point 0 sec1.22.35.40.1-0.7-0.2-2.21.01.71.61.9-0.91.41.40.92.02.32.01.90.3
Patch foraging indifference point AUC0.10.21.90.70.50.41.40.40.1-0.2-0.1-0.10.30.30.0-0.1-0.4-0.2-0.2-0.3
Delay disc. indifference point, 0s delay0.40.51.7-0.3-1.3-1.2-0.7-0.4-0.6-0.6-0.3-0.7-0.2-0.20.8-0.4-0.3-0.20.1-1.2
Delay disc. indifference point, 16s delay0.20.21.20.20.1-0.3-0.40.0-0.2-1.1-0.1-0.5-0.6-0.60.5-0.10.00.20.5-0.8
Delay disc. indifference point, 2s delay1.21.33.5-0.7-1.2-1.6-0.4-1.0-1.5-1.7-1.0-0.8-1.0-1.01.0-1.3-1.1-0.9-0.3-1.9
Delay disc. indifference point, 24s delay0.91.12.10.2-0.4-0.1-1.30.80.91.41.4-1.20.70.71.21.21.41.31.2-0.4
Delay disc. indifference point, 4s delay0.30.31.1-0.4-1.1-0.8-0.5-0.3-0.4-0.5-0.2-0.6-0.2-0.20.7-0.3-0.20.00.1-1.0
Delay disc. indifference point, 8s delay0.60.71.51.20.20.3-0.11.10.8-0.21.0-1.20.60.61.20.81.01.01.1-0.9
Indifference point function ln k0.40.74.1-1.4-1.1-1.3-2.0-1.0-0.8-0.1-0.5-0.0-0.4-0.40.1-0.5-0.0-0.2-0.2-0.0
Indifference point function log k0.40.74.1-1.4-1.1-1.3-2.0-1.0-0.8-0.1-0.5-0.0-0.4-0.40.1-0.5-0.0-0.2-0.2-0.0
Patch foraging total patch changes 0 sec0.81.54.6-0.2-0.5-0.3-2.10.61.31.51.5-0.61.01.00.61.61.91.61.40.6
Patch foraging total patch changes 12 sec0.10.10.3-0.3-0.1-0.2-0.2-0.3-0.10.1-0.20.5-0.1-0.1-0.5-0.1-0.1-0.2-0.20.5
Patch foraging total patch changes 18 sec0.30.41.7-0.5-0.8-0.5-1.1-0.10.41.30.5-0.20.90.90.20.50.40.30.40.2
Patch foraging total patch changes 24 sec0.10.10.50.1-0.0-0.1-0.7-0.30.1-0.5-0.20.6-0.0-0.0-0.50.10.2-0.10.10.6
Patch foraging total patch changes 6 sec0.71.13.0-0.3-1.3-0.8-1.00.50.71.71.2-1.31.01.01.20.91.01.10.9-0.6
Patch foraging time to switch 0 sec0.20.30.7-0.20.40.70.9-0.2-0.30.1-0.60.8-0.5-0.5-0.9-0.5-0.9-0.6-0.70.5
Patch foraging water rate 0 sec0.40.81.90.8-0.5-0.5-0.00.80.60.00.9-1.40.90.91.40.80.90.91.1-1.2
Patch foraging water rate 12 sec0.20.51.2-0.9-0.7-0.8-0.7-1.1-0.90.1-0.80.3-0.8-0.8-0.2-0.7-0.8-0.8-0.6-0.1
Patch foraging water rate 18 sec0.40.61.3-0.30.70.30.5-0.7-0.5-0.2-0.81.1-0.8-0.8-1.1-0.6-0.5-0.8-0.91.1
Patch foraging water rate 24 sec0.10.10.70.30.0-0.00.80.0-0.10.3-0.1-0.10.30.30.1-0.3-0.5-0.3-0.3-0.4
Patch foraging water rate 6 sec0.60.94.2-1.2-2.0-1.7-1.5-0.8-0.41.20.1-0.80.50.50.9-0.00.10.10.2-0.7
Seeking ratio, delayed vs. immediate footshock0.81.01.9-0.70.70.10.9-0.9-0.9-0.1-1.21.0-1.4-1.4-1.1-1.1-1.1-1.0-1.30.7
Distance traveled before self-admin0.30.42.20.31.00.71.50.1-0.4-0.5-0.50.3-0.4-0.4-0.4-0.7-0.7-0.5-0.80.0
Distance traveled after self-admin0.30.32.40.3-0.50.20.30.50.0-1.50.1-0.70.10.10.70.10.00.30.6-1.0
Extensor digitorum longus weight1.24.810.8-1.2-3.1-1.9-2.80.60.93.32.2-2.72.32.32.71.61.92.11.8-1.7
Bone: elastic displacement0.40.51.6-1.3-0.3-0.6-1.0-1.1-0.30.9-0.40.9-0.2-0.2-0.9-0.2-0.1-0.4-0.41.1
Bone: elastic work0.30.41.00.10.60.7-0.20.40.81.00.70.30.60.6-0.30.80.80.60.50.9
Bone: endosteal estimation0.40.93.51.11.91.51.70.5-0.0-1.0-0.40.8-0.6-0.6-0.8-0.4-0.5-0.4-0.70.6
Bone: endosteal perimeter0.20.51.30.01.10.60.9-0.2-0.60.1-0.60.7-0.8-0.8-0.8-0.8-0.8-0.8-1.10.6
Epididymis fat weight1.03.66.71.4-0.8-0.0-0.82.21.60.52.3-2.62.32.32.61.82.52.41.9-1.5
Delta time in closed arm before/after self-admin1.41.35.00.2-0.9-0.4-0.50.90.82.21.5-1.60.90.91.51.01.21.20.9-0.9
Delta time in open arm before/after self-admin3.73.68.1-0.62.30.41.0-1.4-1.7-2.9-2.32.1-2.5-2.5-2.0-2.0-2.0-1.9-1.81.0
Diff in mean of infusions in LGA sessions1.72.15.8-2.4-1.7-2.1-1.7-2.0-1.61.7-0.90.1-1.3-1.3-0.1-1.3-1.0-1.0-1.30.0
Delay discount exponential model param0.30.31.4-0.10.30.60.5-0.00.30.8-0.00.90.40.4-0.90.1-0.1-0.2-0.51.2
Extinction: sum of active levers before priming0.70.71.3-1.1-0.6-1.0-0.9-1.0-1.1-1.0-0.90.1-1.1-1.1-0.0-1.0-0.5-0.7-0.8-0.2
Active lever presses in extinction session 60.10.10.50.10.70.30.40.10.0-0.5-0.20.3-0.3-0.3-0.3-0.1-0.2-0.2-0.10.1
Bone: final force0.50.72.51.61.51.61.51.00.6-1.10.20.30.10.1-0.30.30.20.20.30.3
Bone: final moment0.30.51.91.31.31.41.30.80.5-0.90.10.30.00.0-0.30.20.10.10.20.3
Food consumed during 24 hour testing period1.82.54.6-0.31.00.11.2-1.2-1.8-2.1-2.01.4-1.9-1.9-1.3-2.0-1.9-2.1-1.90.3
Glucose0.50.72.2-0.2-1.1-0.8-0.50.50.30.80.9-1.50.70.71.50.50.70.90.7-1.1
Heart weight0.81.26.9-0.21.61.1-0.5-0.30.71.40.21.8-0.0-0.0-1.80.60.7-0.0-0.32.6
Delay discount hyperbolic model param0.30.31.6-0.20.40.60.3-0.00.30.8-0.00.90.30.3-1.00.20.0-0.1-0.41.3
Intermittent access intake day 1-15 change1.32.75.6-2.4-0.3-1.6-1.3-2.3-2.10.2-1.70.9-2.2-2.2-0.8-1.9-1.5-1.6-1.80.4
Intermittent access intake escalation1.22.45.7-2.3-0.1-1.4-1.3-2.1-1.90.1-1.50.9-2.4-2.4-0.8-1.7-1.3-1.4-1.50.4
Intermittent access intake escalation 23.54.07.9-2.8-0.5-1.8-1.2-2.8-2.70.0-2.21.0-2.6-2.6-0.9-2.5-2.1-2.1-2.30.2
Intermitt. access day 1 inactive lever presses0.10.32.00.10.30.6-0.8-0.20.3-0.10.01.10.20.2-1.10.40.40.10.11.4
Intermitt. access day 15 inactive lever presses0.30.72.6-0.70.80.0-0.6-0.8-0.8-0.8-0.70.7-1.6-1.6-0.7-0.7-0.5-0.4-0.40.5
Intermitt. access escalation Index0.20.20.7-0.8-0.8-0.3-0.6-0.6-0.50.6-0.20.2-0.4-0.4-0.2-0.4-0.2-0.2-0.50.3
Intermittent access day 1 total infusions0.20.42.00.30.10.30.9-0.10.0-1.4-0.50.8-0.6-0.6-0.8-0.1-0.5-0.30.00.4
Intermittent access day 15 total infusions0.50.82.5-1.2-0.7-1.2-1.3-0.9-0.8-0.8-0.60.2-1.6-1.6-0.1-0.5-0.4-0.20.1-0.2
Intermittent access terminal intake (last 3 days)1.52.04.7-2.1-1.1-1.8-1.4-1.9-1.6-0.7-1.40.6-2.2-2.2-0.5-1.3-1.2-1.1-0.8-0.1
Intermittent access total infusions0.70.83.2-0.8-0.7-0.9-0.5-0.8-0.8-1.8-0.90.3-1.5-1.5-0.3-0.6-0.8-0.5-0.0-0.3
Intermittent access day 1 locomotion0.30.44.30.6-0.5-0.2-0.40.20.4-2.1-0.00.0-0.0-0.00.00.50.30.31.0-0.3
Intermittent access day 15 total locomotion0.81.53.7-1.3-1.4-1.9-1.4-1.4-1.5-1.8-1.3-0.1-1.1-1.10.2-1.2-1.1-0.9-0.4-1.0
Intermittent access total locomotion1.82.16.8-1.6-2.0-2.6-1.9-1.6-1.5-1.9-1.3-0.3-1.3-1.30.5-1.2-1.0-0.8-0.2-1.3
Intermittent access standard deviation1.12.34.4-1.30.4-0.8-0.7-1.9-1.8-2.1-2.01.4-2.0-2.0-1.3-1.7-1.6-1.6-1.30.4
Left kidney weight0.20.83.5-0.7-1.3-1.0-0.50.1-0.11.90.7-1.30.90.91.30.00.40.5-0.2-0.9
Right kidney weight0.73.26.60.6-1.4-0.3-0.11.71.32.62.2-2.52.52.52.41.41.61.91.1-1.5
Cocaine induced anxiety0.20.30.4-0.40.0-0.20.2-0.5-0.5-0.2-0.60.6-0.6-0.6-0.6-0.6-0.6-0.6-0.60.4
Post-drug Anxiety0.30.41.0-1.0-0.6-1.0-0.4-0.6-0.9-0.2-0.6-0.2-0.5-0.50.2-0.7-0.7-0.4-0.5-0.6
Baseline Anxiety0.30.41.1-0.7-0.8-0.8-0.7-0.1-0.20.70.3-1.00.20.21.00.00.00.40.3-1.1
Tail length2.07.624.65.04.14.44.64.12.9-0.62.1-0.51.91.90.22.01.61.61.30.3
Length with tail2.29.731.35.64.75.04.84.63.2-0.72.5-0.72.22.20.42.22.02.01.40.3
Length without tail1.44.411.53.41.92.43.03.32.0-0.12.1-1.91.71.71.71.61.62.01.4-1.2
Times rat made contact with spout1.01.22.90.21.20.90.1-0.7-0.7-1.3-1.11.7-1.1-1.1-1.7-0.8-0.7-1.2-1.01.4
Lifetime Intake0.50.63.0-0.7-0.7-1.0-0.5-0.6-0.7-1.7-0.70.1-1.3-1.3-0.0-0.4-0.6-0.30.2-0.5
Liver weight, left1.32.15.70.52.01.81.3-0.5-0.5-0.7-1.22.3-1.1-1.1-2.4-0.9-0.8-1.3-1.62.3
Liver weight, right0.71.22.9-1.0-0.20.1-1.0-1.3-0.8-0.4-1.11.7-1.0-1.0-1.7-0.8-0.6-1.0-1.21.7
Locomotor activity0.20.32.9-0.5-0.1-0.4-1.7-0.10.20.00.40.0-0.4-0.40.00.50.80.70.60.5
Locomotor testing distance0.20.31.6-0.20.4-0.0-1.3-0.10.30.10.30.3-0.6-0.6-0.30.60.70.60.60.7
Locomotor testing rearing0.10.10.6-0.00.20.0-0.7-0.00.30.20.30.2-0.1-0.1-0.20.40.60.50.30.6
Locomotion in novel chamber1.01.22.9-1.7-0.9-1.4-0.8-1.6-1.50.5-1.20.3-1.0-1.0-0.3-1.4-1.1-1.0-1.4-0.0
Locomotion in novel chamber post-restriction0.50.91.70.6-0.1-0.3-0.80.91.10.41.2-1.01.01.01.01.21.31.21.3-0.4
Fecal boli incidents, locomotor time 10.30.42.30.81.20.71.50.5-0.1-0.7-0.20.3-0.3-0.3-0.4-0.3-0.2-0.3-0.50.2
Change in fecal boli incidents, locomotor task0.10.10.8-0.50.2-0.2-0.9-0.5-0.1-0.5-0.30.5-0.3-0.3-0.4-0.0-0.0-0.10.10.4
Time >=10cm from walls, locomotor time 11.11.24.41.01.61.40.10.10.8-1.0-0.11.90.30.3-1.90.60.4-0.20.32.1
Bouts of movement, locomotor time 10.70.83.50.41.21.2-0.30.20.90.80.51.20.40.4-1.20.80.80.40.11.9
Total resting periods, locomotor time 10.80.94.00.41.01.2-0.50.11.00.70.51.30.60.6-1.30.90.90.40.32.0
Rest time, locomotor task time 10.60.73.30.31.41.4-0.30.20.70.40.41.10.30.3-1.20.60.80.3-0.01.8
Distance moved, locomotor task time 11.21.73.41.6-0.9-0.00.61.61.1-0.51.1-1.81.51.51.81.00.91.21.6-1.8
Vertical activity count, locomotor time 10.20.41.10.5-1.0-0.40.30.50.3-0.00.4-1.00.50.51.00.30.10.50.6-1.1
Time >=10cm from walls, locomotor time 20.60.82.0-0.11.10.30.5-0.7-0.5-1.2-1.01.4-0.9-0.9-1.4-0.7-0.8-1.0-0.71.0
Bouts of movement, locomotor time 20.50.73.6-0.1-0.8-0.4-1.90.20.70.80.9-0.50.70.70.61.01.21.11.00.1
Total resting periods, locomotor time 20.30.53.20.0-0.3-0.0-1.80.10.60.40.7-0.10.50.50.10.91.20.90.80.6
Rest time, locomotor task time 20.91.25.30.31.51.4-0.30.41.21.30.71.20.30.3-1.31.01.30.60.12.3
Distance moved, locomotor task time 20.81.03.90.8-1.1-0.50.10.80.3-1.10.5-1.60.90.91.70.30.30.51.1-2.0
Vertical activity count, locomotor time 20.81.24.5-1.2-2.1-1.8-0.9-0.9-1.3-0.3-0.6-1.0-0.2-0.21.1-1.0-0.8-0.4-0.3-1.6
Light reinforcement 10.71.75.2-2.3-1.7-1.9-0.6-1.7-1.61.9-0.9-0.2-0.8-0.80.2-1.3-1.2-1.0-1.4-0.4
Light reinforcement 20.61.03.0-0.20.60.21.7-0.5-1.0-0.1-1.10.6-1.2-1.2-0.7-1.2-1.4-1.2-1.50.0
Bone: marrow area0.30.73.21.11.81.51.60.60.1-0.9-0.20.6-0.5-0.5-0.7-0.2-0.3-0.2-0.50.5
Bone: maximum diameter0.40.71.80.71.31.20.10.91.10.40.90.30.70.7-0.41.01.00.70.51.0
Bone: maximum force0.30.52.70.91.11.01.60.4-0.1-1.3-0.40.3-0.5-0.5-0.4-0.3-0.5-0.4-0.3-0.0
Bone: maximum moment0.20.41.80.60.80.71.30.1-0.3-1.1-0.50.3-0.6-0.6-0.3-0.5-0.6-0.5-0.4-0.1
Mean time between licks in bursts0.20.54.4-0.6-0.9-0.8-2.1-0.2-0.10.10.3-0.40.60.60.40.20.70.40.30.0
Mean num. licks in bursts0.91.43.50.21.00.70.2-1.0-0.7-1.8-1.41.9-1.0-1.0-1.8-0.9-0.9-1.5-1.01.3
Cd content in liver2.12.34.2-1.4-0.4-1.10.5-1.7-2.0-1.0-1.90.8-2.0-2.0-0.7-2.0-2.1-1.9-1.7-0.3
Co content in liver0.10.21.60.00.2-0.1-0.2-0.2-0.3-1.3-0.50.3-0.4-0.4-0.2-0.3-0.1-0.20.00.0
Cu content in liver2.63.15.11.5-0.40.4-0.22.11.80.82.2-2.02.12.12.02.02.02.32.1-1.2
Fe content in liver0.50.73.40.31.11.30.10.00.60.90.21.30.00.0-1.30.50.40.1-0.21.8
K content in liver1.61.53.00.5-0.9-0.3-0.31.31.11.11.5-1.71.41.41.71.21.31.61.4-1.1
Mg content in liver1.41.52.40.5-0.8-0.2-0.31.21.11.51.5-1.51.51.51.51.31.31.51.3-0.8
Mn content in liver0.91.04.9-1.9-1.3-1.3-1.7-1.2-0.62.2-0.10.1-0.1-0.1-0.1-0.3-0.1-0.1-0.50.5
Na content in liver0.20.20.50.50.30.50.70.60.40.70.5-0.30.20.20.20.40.20.30.2-0.1
Rb content in liver0.60.72.30.2-0.5-0.1-1.50.40.9-0.40.7-0.40.90.90.41.11.31.11.40.0
Se content in liver0.60.71.50.7-0.30.2-0.61.00.90.31.1-0.81.11.10.81.01.21.21.0-0.2
Sr content in liver1.41.26.9-0.51.10.9-0.7-0.70.31.4-0.11.9-0.2-0.2-1.90.30.4-0.2-0.62.6
Zn content in liver0.91.02.00.8-0.5-0.1-0.51.10.8-0.01.1-1.41.21.21.40.91.11.31.2-1.0
Bone: minimum diameter0.71.33.91.51.82.01.41.61.40.21.10.10.80.8-0.21.21.10.90.70.7
Time in familiar zone, hab. session 12.32.34.7-2.0-1.4-2.2-1.1-1.9-2.1-0.7-1.6-0.0-1.7-1.70.2-1.8-1.7-1.3-1.2-1.0
Time in novel zone, hab. session 12.22.27.41.42.72.71.81.01.30.70.51.70.50.5-1.90.90.60.1-0.22.4
Total zone transitions, hab. session 11.62.34.31.70.71.41.22.12.11.41.9-1.01.61.60.81.91.41.61.6-0.2
Total locomotion distance, hab. session 10.91.22.51.11.31.61.21.31.61.21.20.20.70.7-0.31.41.00.90.90.8
Locomotion velocity, hab. session 11.41.93.91.51.11.61.11.82.01.51.8-0.41.21.20.31.91.51.41.40.4
Time in familiar zone, hab. session 21.31.33.2-0.9-0.7-0.90.4-1.1-1.6-1.3-1.50.2-1.3-1.3-0.1-1.6-1.8-1.4-1.2-0.9
Time in novel zone, hab. session 20.90.93.00.30.50.6-0.60.61.11.71.20.10.80.8-0.11.21.41.00.61.1
Total zone transitions, hab. session 20.00.00.1-0.2-0.00.1-0.0-0.2-0.20.1-0.20.3-0.0-0.0-0.3-0.2-0.1-0.3-0.30.3
Total locomotion distance, hab. session 20.00.10.4-0.4-0.00.0-0.4-0.10.10.60.10.20.00.0-0.20.10.2-0.1-0.10.5
Locomotion velocity, hab. session 20.00.00.3-0.4-0.00.0-0.30.00.10.60.20.00.10.1-0.00.20.2-0.00.00.3
Novel to familiar place preference ratio0.80.92.81.61.21.21.71.41.00.50.9-0.60.50.50.50.80.40.80.5-0.4
Novelty place preference0.60.62.71.21.31.11.71.10.70.70.7-0.40.20.20.20.50.20.60.2-0.2
Time in novel zone, NPP test0.60.63.71.21.41.21.91.00.60.80.5-0.20.00.00.10.3-0.00.4-0.1-0.0
Total zone transitions, NPP test0.00.00.3-0.00.00.20.00.10.10.60.10.10.20.2-0.10.10.1-0.0-0.10.3
Total locomotion distance, NPP test0.10.21.1-0.10.40.40.10.20.51.00.40.30.30.3-0.30.50.30.20.10.6
Locomotion velocity, NPP test0.10.20.7-0.20.10.2-0.30.20.50.80.40.10.40.4-0.10.50.50.30.30.4
Intraocular pressure0.81.12.7-1.3-1.5-1.7-1.5-1.4-1.3-1.0-1.1-0.0-0.3-0.30.2-1.1-0.9-0.8-0.6-0.7
Delta distance traveled before/after self-admin0.60.71.6-0.1-1.2-0.5-1.20.40.5-0.50.7-1.00.50.51.10.80.80.91.3-0.9
Delta ambulatory time before/after self-admin0.81.02.60.5-1.2-0.1-1.00.80.9-0.80.9-0.91.01.01.01.11.11.11.6-0.7
Parametrial fat weight1.12.76.52.60.11.31.32.31.5-0.71.7-1.52.42.41.41.41.51.51.3-0.9
Pavlov. Cond. lever latency3.34.17.1-2.1-0.3-1.10.0-2.6-2.5-1.2-2.71.8-2.3-2.3-1.7-2.6-2.5-2.4-2.50.7
Pavlov. Cond. magazine entry latency1.41.75.02.21.21.61.52.01.6-0.01.4-0.81.21.20.71.41.01.21.3-0.5
Pavlov. Cond. change in total contacts3.03.15.21.9-0.10.60.62.32.00.82.2-2.11.91.92.02.01.62.22.3-1.6
Pavlov. Cond. index score2.12.75.32.20.71.40.72.32.10.62.0-1.31.71.71.22.01.71.81.9-0.6
Pavlov. Cond. latency score2.02.55.02.10.71.30.72.22.00.62.0-1.31.61.61.21.91.71.81.9-0.6
Pavlov. Cond. lever contacts2.52.95.11.60.10.7-0.42.12.11.12.3-1.61.91.91.52.22.22.12.2-0.6
Pavlov. Cond. magazine entry number1.51.93.9-2.0-0.6-1.2-1.0-2.0-1.8-0.3-1.61.1-1.4-1.4-1.0-1.6-1.2-1.5-1.60.7
Pavlov. Cond. intertrial magazine entries0.50.62.4-0.9-0.1-0.0-1.5-0.50.31.60.30.70.30.3-0.70.40.70.2-0.11.4
Pavlov. Cond. lever-magazine prob. diff.1.72.14.22.00.71.20.62.11.90.41.8-1.21.51.51.11.81.51.61.8-0.7
Pavlov. Cond. response bias2.73.46.02.30.91.50.52.52.50.82.3-1.22.12.11.12.32.12.22.2-0.3
Pavlov. Cond. lever latency0.60.92.9-0.0-1.4-0.8-0.10.50.20.90.8-1.70.70.71.70.40.60.90.6-1.4
Pavlov. Cond. magazine entry latency1.72.14.0-0.90.6-0.30.1-1.6-1.4-1.2-2.01.8-1.6-1.6-1.8-1.6-1.8-2.0-1.60.9
Pavlov. Cond. change in total contacts0.50.72.60.31.50.90.5-0.30.1-0.5-0.61.6-0.4-0.4-1.6-0.1-0.4-0.7-0.51.4
Pavlov. Cond. index score1.52.06.0-0.41.60.70.0-1.2-0.7-1.2-1.62.4-1.3-1.3-2.4-1.0-1.2-1.6-1.31.9
Pavlov. Cond. latency score1.31.74.8-0.31.50.60.2-1.1-0.6-1.2-1.52.2-1.1-1.1-2.2-0.9-1.1-1.6-1.21.6
Pavlov. Cond. lever contacts0.91.24.00.11.81.10.4-0.5-0.1-0.8-0.92.0-0.8-0.8-2.0-0.4-0.6-0.9-0.71.8
Pavlov. Cond. magazine entry number1.82.25.40.9-0.9-0.00.21.71.10.91.8-2.31.41.42.31.31.41.91.6-1.7
Pavlov. Cond. intertrial magazine entries3.75.511.41.4-1.5-0.1-0.12.62.02.13.0-3.42.52.53.32.32.33.02.5-2.3
Pavlov. Cond. lever-magazine prob. diff.1.82.46.7-0.61.50.5-0.1-1.5-0.9-1.2-1.82.6-1.4-1.4-2.5-1.2-1.3-1.8-1.42.0
Pavlov. Cond. response bias1.52.06.3-0.31.70.90.1-1.1-0.6-1.1-1.52.5-1.3-1.3-2.5-0.8-1.0-1.4-1.22.1
Time in closed arm before self-admin1.31.74.10.51.61.51.7-0.4-0.5-1.8-1.32.0-0.3-0.3-2.0-0.9-1.2-1.2-1.31.5
Time in closed arm after self-admin0.50.61.61.20.31.01.00.90.80.80.6-0.11.31.30.00.60.40.40.20.3
Time in open arm before self-admin2.93.18.5-0.8-2.2-1.2-2.70.61.32.92.1-1.81.01.01.81.92.11.91.9-0.5
Time in open arm after self-admin1.11.23.3-0.90.90.10.1-1.0-0.9-1.2-1.21.4-1.8-1.8-1.3-0.9-1.0-1.0-0.90.9
Bone: periosteal estimation0.51.23.21.51.81.71.11.51.3-0.31.00.10.80.8-0.21.11.00.80.80.6
Bone: periosteal perimeter0.20.41.90.11.40.90.5-0.00.00.1-0.21.0-0.3-0.3-1.0-0.1-0.1-0.4-0.61.2
Bone: post-yield work1.52.24.9-0.7-0.1-0.70.7-1.3-1.9-2.2-2.00.6-1.9-1.9-0.5-2.0-2.1-1.7-1.5-0.7
Progressive ratio test 1 active lever presses0.20.20.5-0.1-0.1-0.3-0.50.10.4-0.70.10.4-0.7-0.7-0.30.50.50.40.60.5
Progressive ratio test 1 breakpoint0.20.20.50.1-0.0-0.2-0.30.20.5-0.70.20.3-0.6-0.6-0.30.60.50.40.70.5
Progressive ratio test 1 inactive lever presses0.30.52.10.1-0.5-0.4-1.40.40.6-0.50.7-0.30.10.10.40.81.11.01.00.2
Progressive ratio test 2 active lever presses0.20.20.8-0.5-0.1-0.4-0.9-0.3-0.1-0.4-0.00.3-0.7-0.7-0.30.10.20.20.30.3
Progressive ratio test 2 breakpoint0.10.20.6-0.50.1-0.3-0.8-0.3-0.0-0.3-0.00.4-0.7-0.7-0.40.20.20.20.30.4
Progressive ratio test 2 inactive lever presses0.61.02.7-1.3-0.6-1.0-1.6-1.3-1.0-1.3-1.00.7-1.1-1.1-0.6-0.8-0.5-0.7-0.40.3
Incentive Sensitization - Responses0.10.20.6-0.60.1-0.2-0.8-0.6-0.4-0.4-0.40.5-0.4-0.4-0.5-0.3-0.3-0.3-0.20.3
Incentive Sensitization - Breakpoint0.10.10.5-0.50.1-0.2-0.7-0.5-0.4-0.4-0.40.5-0.4-0.4-0.4-0.3-0.2-0.2-0.10.3
Sum of active levers in priming session hrs 5-60.70.72.01.40.60.90.61.30.90.21.0-0.70.80.80.60.81.00.80.7-0.2
Progressive ratio0.71.12.41.00.20.7-0.50.91.50.51.10.21.51.5-0.31.51.41.11.11.0
Food seeking constrained by brief footshock0.91.14.3-1.3-2.1-2.0-1.4-0.7-0.91.0-0.1-1.20.10.11.2-0.5-0.3-0.1-0.3-1.3
Seeking ratio, punishment vs. effort0.81.23.4-1.0-1.1-1.30.1-0.8-1.6-0.1-0.8-1.1-1.0-1.01.1-1.4-1.3-0.8-0.8-1.9
Retroperitoneal fat weight0.83.38.01.5-1.5-0.4-0.32.01.0-0.71.7-2.82.32.32.81.21.71.91.6-2.3
Reaction time number correct0.51.04.0-1.9-0.8-1.1-1.1-1.5-0.82.0-0.50.6-0.4-0.4-0.6-0.5-0.5-0.5-0.90.7
Reaction time mean minus median0.20.51.3-0.2-0.10.10.8-0.7-0.80.0-0.80.8-0.5-0.5-0.8-0.9-0.9-0.9-1.20.5
Reaction time mean minus median AUC0.30.81.9-0.40.20.20.7-0.9-1.0-0.1-1.11.1-0.7-0.7-1.1-1.1-1.1-1.1-1.40.8
Reaction time num false alarms0.81.24.3-1.1-2.1-1.9-1.8-0.4-0.50.40.2-1.50.60.61.5-0.10.20.40.2-1.4
Reaction time num false alarms AUC0.71.03.4-1.0-1.8-1.6-1.5-0.2-0.30.80.5-1.40.70.71.50.10.40.60.3-1.2
Reaction time trials correct on left0.51.04.0-1.9-0.8-1.1-1.1-1.5-0.82.0-0.50.6-0.4-0.4-0.6-0.5-0.5-0.5-0.90.7
Reaction time trials on left0.51.04.2-1.9-0.8-1.0-1.1-1.4-0.82.1-0.40.5-0.4-0.4-0.5-0.5-0.5-0.5-0.90.7
Reaction time mean1.11.86.52.12.52.21.50.80.8-2.0-0.21.5-0.1-0.1-1.60.30.3-0.20.01.6
Reaction time mean AUC1.01.65.22.22.32.21.51.21.0-1.70.21.10.20.2-1.10.60.50.10.41.2
Median of all reaction times2.02.910.02.83.22.81.41.61.6-2.30.41.40.40.4-1.41.11.00.50.91.6
Reaction time omissions0.10.10.60.50.00.70.70.2-0.20.2-0.10.10.30.3-0.2-0.4-0.3-0.3-0.80.2
Reaction time false alarm rate0.71.03.10.4-1.2-0.8-0.50.80.2-0.40.8-1.71.01.01.80.40.60.90.8-1.6
Reaction time premature initiation rate0.40.51.6-0.50.70.2-0.4-0.7-0.4-0.4-0.61.2-0.6-0.6-1.2-0.4-0.2-0.7-0.61.3
Reaction time premature initiations0.81.32.9-1.60.2-0.5-0.9-1.7-1.00.6-1.11.6-1.0-1.0-1.5-0.9-0.7-1.1-1.31.6
Std. dev. reaction times0.50.92.71.01.01.11.6-0.1-0.4-1.1-0.91.2-0.4-0.4-1.2-0.7-0.8-1.0-1.00.8
Reaction time trials completed0.51.04.2-1.9-0.8-1.0-1.1-1.4-0.82.1-0.40.5-0.4-0.4-0.5-0.5-0.5-0.5-0.90.7
Reaction time trials AUC0.50.93.5-1.8-0.6-0.9-1.0-1.4-0.71.9-0.50.6-0.4-0.4-0.6-0.5-0.5-0.5-0.90.8
Run reversals in cocaine runway, females0.60.61.30.9-0.60.30.30.90.80.10.8-0.70.90.90.70.90.50.61.1-0.7
Run reversals in cocaine runway, males0.20.20.70.70.60.50.80.60.3-0.20.2-0.30.30.30.30.20.10.20.2-0.3
Latency to leave start box in cocaine runway1.92.25.7-0.1-1.6-0.9-2.40.71.31.41.7-1.41.41.41.41.72.21.71.8-0.3
Latency to leave start box in cocaine runway, F1.41.63.30.1-1.8-0.8-1.80.70.91.01.4-1.51.31.31.51.31.71.31.4-0.7
Latency to leave start box in cocaine runway, M0.40.42.4-0.7-0.3-0.6-1.6-0.30.40.50.40.10.00.0-0.00.60.80.60.60.5
Std. dev. time between licks in bursts1.01.44.7-1.5-2.2-1.8-2.0-0.5-0.02.00.7-1.10.80.81.20.40.60.70.4-0.6
Total sessions with >9 infusions0.20.20.7-0.10.3-0.2-0.7-0.00.4-0.80.10.4-0.6-0.6-0.30.50.50.20.70.5
Short access day 1 total inactive lever presses0.50.62.3-0.3-0.9-1.3-1.0-0.0-0.3-1.5-0.0-0.9-0.3-0.31.0-0.00.10.30.8-1.3
Short access day 10 total inactive lever presses0.10.20.60.60.50.8-0.20.40.4-0.30.40.20.60.6-0.20.40.50.30.30.5
Short access day 1 total infusions0.30.31.3-0.8-0.5-1.1-1.1-0.5-0.5-0.6-0.2-0.4-0.7-0.70.4-0.2-0.0-0.00.2-0.6
Short access day 10 total infusions0.10.10.8-0.3-0.5-0.50.2-0.00.0-0.9-0.10.2-0.6-0.6-0.10.2-0.10.00.3-0.0
Short access total infusions0.30.41.3-0.6-0.9-1.0-0.8-0.6-0.4-1.1-0.4-0.1-0.7-0.70.2-0.2-0.2-0.10.3-0.4
Short access day 1 locomotion0.50.61.80.50.90.4-0.40.81.1-0.01.0-0.00.10.1-0.01.21.30.91.20.6
Short access day 10 total locomotion0.30.52.3-0.4-0.3-0.8-0.7-0.9-0.5-1.5-0.90.8-0.3-0.3-0.7-0.5-0.4-0.8-0.40.4
Short access total locomotion0.30.41.9-0.2-0.6-1.0-1.3-0.30.1-1.4-0.1-0.1-0.1-0.10.20.30.40.10.8-0.3
One hour access (0.3 mA shock)0.40.53.4-0.3-0.3-0.8-0.4-0.7-0.7-1.8-0.90.4-0.7-0.7-0.3-0.7-0.6-0.6-0.2-0.2
Compulsive drug intake0.20.20.70.5-0.30.2-0.20.30.6-0.20.30.30.80.8-0.30.60.50.20.40.5
One hour access (shock baseline)0.40.62.1-0.30.1-0.50.3-0.6-1.0-1.5-1.00.3-1.2-1.2-0.2-1.0-1.0-0.7-0.6-0.4
Social response proportion0.30.30.70.3-0.1-0.00.10.70.30.80.7-0.90.50.50.80.30.40.70.2-0.5
Social responses0.10.10.50.30.60.40.60.40.30.70.30.00.50.5-0.10.10.10.2-0.30.3
Social time0.30.40.9-0.50.80.0-0.2-0.8-0.50.4-0.60.9-0.6-0.6-0.9-0.6-0.5-0.7-0.90.9
Soleus weight0.20.64.5-1.2-0.6-0.50.1-0.8-0.72.1-0.30.1-0.4-0.4-0.2-0.6-0.8-0.7-1.00.2
Bone: stiffness0.40.63.00.70.80.61.70.2-0.5-1.4-0.60.1-0.7-0.7-0.1-0.8-0.8-0.6-0.7-0.4
Tibialis anterior weight0.20.51.8-0.9-1.3-1.2-0.9-0.4-0.40.70.1-1.00.30.31.0-0.1-0.20.10.2-1.2
Time to tail flick, vehicle, before self-admin0.20.20.60.50.70.70.50.20.40.40.20.50.40.4-0.60.30.1-0.1-0.10.7
Time to tail flick, vehicle, after self-admin0.50.61.60.21.01.11.2-0.1-0.00.2-0.41.2-0.3-0.3-1.2-0.3-0.5-0.7-0.91.3
Time to tail flick, test, before self-admin0.80.92.91.70.31.41.51.20.9-0.20.6-0.21.51.50.10.60.20.30.4-0.1
Time to tail flick, test, after self-admin3.03.28.2-2.3-2.1-2.9-2.1-2.3-2.3-1.2-1.7-0.3-1.9-1.90.4-1.9-1.3-1.2-1.1-1.1
Delta time to tail flick, vehicle, before/after SA1.21.22.0-1.0-0.3-0.60.2-1.2-1.3-1.3-1.40.6-1.4-1.4-0.6-1.3-1.4-1.2-1.1-0.1
Delta time to tail flick, test, before/after SA4.54.611.3-3.4-1.6-3.2-2.9-3.0-2.6-0.6-2.00.5-2.7-2.7-0.3-2.1-1.4-1.5-1.5-0.2
Tibia length0.92.57.02.62.12.62.22.31.7-1.21.2-0.21.21.20.01.31.21.11.10.3
Ambulatory time before self-admin0.60.82.2-0.20.70.21.5-0.5-1.1-0.8-1.10.3-0.8-0.8-0.4-1.3-1.4-1.0-1.3-0.3
Ambulatory time after self-admin0.40.51.40.2-1.1-0.2-0.30.60.1-1.20.4-1.00.50.51.00.30.40.50.8-1.1
Bone: tissue strength0.30.31.80.0-0.5-0.41.10.2-0.4-0.5-0.1-0.9-0.2-0.20.9-0.4-0.5-0.1-0.0-1.4
Total heroin consumption0.30.31.00.50.70.50.7-0.1-0.5-1.0-0.60.5-0.2-0.2-0.5-0.7-0.5-0.6-0.70.3
Bone: trabecular number0.20.31.1-0.1-0.8-0.40.50.2-0.10.70.3-0.90.20.20.9-0.0-0.20.10.1-1.0
Bone: trabecular spacing0.91.22.51.61.31.3-0.11.21.4-1.60.70.41.01.0-0.41.21.30.81.30.7
Bone: trabecular thickness0.91.13.1-0.40.50.01.8-0.6-1.1-0.3-1.10.5-1.3-1.3-0.5-1.3-1.6-1.4-1.4-0.2
Bone: trabecular tissue density0.81.25.90.71.20.9-1.0-0.50.2-2.4-0.71.9-0.3-0.3-1.80.10.4-0.30.21.9
Water consumed over 24 hours0.30.40.7-0.70.2-0.2-0.3-0.8-0.8-0.0-0.70.8-0.8-0.8-0.8-0.7-0.6-0.8-0.90.6
Number of responses in last shaping day2.12.34.41.71.11.70.72.12.11.22.0-0.71.51.50.62.01.91.61.50.3