Hub : Genes

Abhd1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose isoform ratio NM_001008520.1 0.04 0.04 8.7e-04 0.02 0.02 0.02 0.02 1.4e-03 1.7e-03 2.8e-03 1.9e-03
2 Adipose isoform ratio XM_063261874.1 0.04 0.04 1.1e-03 0.02 0.02 0.02 0.02 1.4e-03 1.6e-03 2.6e-03 1.7e-03
3 NAcc gene expression Abhd1 0.08 0.05 8.3e-10 0.04 0.06 0.05 0.05 8.4e-07 2.4e-09 3.1e-08 2.7e-08
4 BLA gene expression Abhd1 0.15 0.15 9.0e-04 0.04 0.03 0.03 0.04 3.3e-03 1.7e-02 1.4e-02 4.7e-03
5 Eye isoform ratio NM_001008520.1 0.38 0.28 7.4e-03 0.1 0.06 0.03 0.06 1.3e-02 5.2e-02 1.1e-01 5.1e-02
6 Brain isoform ratio XM_063261874.1 0.03 0.03 9.3e-04 0.02 0.03 0.02 0.02 3.4e-03 8.3e-04 4.4e-03 6.0e-03
7 PL isoform ratio XM_063261874.1 0.03 0.02 2.1e-03 0.02 0.02 0.02 0.02 2.0e-03 2.1e-03 1.5e-03 1.8e-03
8 Adipose mRNA stability Abhd1 0.05 0.05 4.2e-05 0.03 0.04 0.04 0.04 9.6e-05 6.1e-05 6.3e-05 6.3e-05
9 PL alternative TSS XM_063261874.1 0.04 0.03 8.0e-05 0.04 0.04 0.04 0.04 7.7e-05 3.6e-05 1.9e-05 2.0e-05
10 PL alternative TSS XM_039112176.2 0.04 0.03 1.4e-05 0.05 0.05 0.05 0.05 7.3e-06 7.7e-06 5.3e-06 3.7e-06
11 PL alternative TSS XM_063261874.1 0.04 0.03 2.5e-05 0.04 0.04 0.05 0.05 1.4e-05 1.5e-05 6.8e-06 5.9e-06
12 pVTA gene expression Abhd1 0.03 0.03 4.3e-04 0.04 0.04 0.03 0.04 5.8e-04 2.8e-04 1.5e-03 7.7e-04
13 PL gene expression Abhd1 0.13 0.15 8.2e-08 0.08 0.07 0.08 0.08 7.1e-09 2.8e-08 8.0e-09 1.0e-08
14 Adipose gene expression Abhd1 0.03 0.03 2.3e-03 0.02 0.02 0 0.02 3.3e-03 3.9e-03 7.5e-02 4.8e-03
15 Liver isoform ratio NM_001008520.1 0.07 0.06 1.4e-06 0.04 0.04 0.04 0.04 1.6e-05 1.2e-05 1.0e-05 1.1e-05
16 PL intron excision ratio chr6_31143938_31144081 0.05 0.07 7.1e-03 0.02 0.01 0 0.01 6.4e-03 8.8e-03 1.9e-01 7.8e-03
17 Liver mRNA stability Abhd1 0.04 0.04 8.1e-04 0.02 0.02 0.02 0.02 1.4e-03 2.4e-03 1.5e-03 2.3e-03
18 Brain alternative TSS XM_063261874.1 0.05 0.03 2.6e-05 0.05 0.04 0.04 0.04 3.3e-05 8.8e-05 1.8e-04 2.2e-04
19 Brain alternative TSS XM_039112176.2 0.04 0.03 6.2e-05 0.04 0.04 0.03 0.03 1.0e-04 1.9e-04 4.3e-04 3.9e-04
20 Brain alternative TSS XM_063261874.1 0.04 0.03 4.0e-05 0.04 0.04 0.04 0.04 6.8e-05 1.4e-04 2.8e-04 2.6e-04
21 Brain gene expression Abhd1 0.04 0.03 6.7e-05 0.03 0.03 0.03 0.03 5.5e-04 5.7e-04 1.5e-03 1.1e-03
22 Brain alternative TSS NM_001008520.1 0.02 0.02 6.3e-03 0.01 0.01 0.01 0.01 1.6e-02 2.3e-02 8.3e-02 2.3e-02
23 pVTA mRNA stability Abhd1 0.06 0.05 4.4e-03 0.03 0.03 0.03 0.03 1.4e-03 2.2e-03 1.7e-03 4.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bone: apparent density3.56.59.1-1.71.7-2.41.9-2.0-2.73.02.73.03.0-3.0-2.82.73.0-2.7-2.8-2.72.7-2.72.72.0-2.0-1.9
Area under the delay curve0.00.00.3-0.10.1-0.20.30.1-0.20.20.20.20.2-0.2-0.20.60.2-0.3-0.1-0.40.1-0.10.1-0.00.00.2
BMI with tail0.62.17.52.5-2.51.9-2.72.01.4-1.1-1.3-0.9-0.80.81.1-0.8-0.91.11.20.9-1.21.2-1.2-0.80.81.0
BMI without tail0.52.76.42.2-2.22.0-2.52.11.7-1.5-1.6-1.4-1.41.41.4-1.1-1.31.41.61.2-1.61.6-1.6-1.21.21.4
Body weight2.410.513.63.4-3.43.5-3.53.73.4-3.2-3.3-3.1-3.13.13.2-2.8-3.03.13.32.8-3.33.3-3.3-3.23.23.3
Weight adjusted by age0.10.20.50.3-0.3-0.10.1-0.7-0.30.20.30.20.1-0.1-0.30.50.2-0.4-0.4-0.40.5-0.50.50.7-0.7-0.5
Bone surface1.73.35.8-0.60.6-1.30.8-0.9-1.92.31.92.42.4-2.4-2.12.22.4-2.2-2.1-2.22.0-2.02.00.8-0.8-0.9
Bone volume1.73.55.8-1.11.1-1.61.1-1.0-2.02.32.02.42.4-2.4-2.12.12.3-2.1-2.1-2.12.0-2.02.00.9-0.9-0.9
Breakpoint value in progressive ratio session0.50.91.6-0.80.8-1.00.3-0.6-0.90.71.00.70.7-0.7-0.91.10.9-1.2-1.2-1.11.3-1.31.30.9-0.9-0.8
Number of licking bursts0.10.31.51.0-1.00.7-1.21.00.20.1-0.20.30.3-0.3-0.00.20.2-0.1-0.0-0.2-0.20.2-0.2-0.40.40.4
Context. condit. distance diff. score0.00.00.2-0.40.4-0.30.4-0.5-0.10.10.10.00.0-0.0-0.00.1-0.0-0.0-0.0-0.1-0.10.1-0.10.1-0.1-0.2
Locomotion velocity, session 10.20.20.80.8-0.80.5-0.30.80.2-0.0-0.20.10.0-0.00.1-0.20.00.30.30.2-0.40.4-0.4-0.80.80.9
Locomotion distance, session 11.11.42.8-0.30.3-0.91.1-0.5-1.31.61.31.71.7-1.7-1.41.21.7-1.3-1.3-1.21.2-1.21.20.5-0.5-0.3
Locomotion velocity, session 20.30.30.50.4-0.40.5-0.50.50.6-0.5-0.6-0.5-0.50.50.6-0.6-0.50.70.70.6-0.70.7-0.7-0.30.30.5
Locomotion distance, session 20.00.10.40.7-0.70.2-0.10.40.10.2-0.10.10.1-0.1-0.0-0.20.10.10.00.2-0.00.0-0.0-0.10.10.3
Locomotion velocity, session 30.70.91.6-0.20.2-0.80.6-1.3-0.90.90.90.90.8-0.8-0.90.80.8-0.9-1.0-0.81.1-1.11.11.2-1.2-1.2
Locomotion distance, session 30.50.61.00.5-0.5-0.40.2-0.4-0.71.00.81.01.0-1.0-0.90.71.0-0.8-0.9-0.70.8-0.80.80.5-0.5-0.5
Stereotopy head waving bouts, day 32.32.73.6-1.61.6-1.71.1-1.8-1.71.51.71.51.4-1.4-1.61.71.5-1.7-1.6-1.71.7-1.71.71.9-1.9-1.9
Stereotopy head waving duration, day 30.30.40.8-0.90.9-0.70.3-0.7-0.50.30.60.30.3-0.3-0.50.50.3-0.5-0.5-0.50.7-0.70.70.7-0.7-0.8
Locomotion velocity, session 70.80.91.50.1-0.1-0.6-0.2-0.2-0.91.21.01.21.2-1.2-1.21.21.2-1.2-1.2-1.21.1-1.11.10.5-0.5-0.4
Locomotion distance, session 70.20.31.41.2-1.20.5-1.10.90.00.20.00.40.4-0.4-0.20.30.4-0.4-0.4-0.30.2-0.20.2-0.40.40.6
Stereotopy head waving bouts, day 70.00.00.20.3-0.30.1-0.3-0.5-0.10.10.10.10.1-0.1-0.10.10.10.00.0-0.10.0-0.00.00.3-0.3-0.5
Stereotopy head waving duration, day 70.50.61.9-0.60.6-0.80.7-1.4-0.70.60.70.50.5-0.5-0.60.70.5-0.6-0.5-0.70.6-0.60.61.1-1.1-1.3
Locomotion velocity, session 80.30.40.7-0.60.6-0.70.6-0.8-0.60.60.60.50.5-0.5-0.60.60.5-0.6-0.6-0.60.5-0.50.50.5-0.5-0.6
Locomotion distance, session 80.20.30.6-0.40.4-0.60.7-0.5-0.60.80.60.70.7-0.7-0.60.60.7-0.6-0.6-0.60.5-0.50.50.4-0.4-0.4
Degree of sensitization distance0.91.02.00.9-0.91.1-1.41.41.0-1.0-1.0-0.9-0.90.90.9-0.7-0.90.80.80.7-1.01.0-1.0-1.21.21.2
Degree of sensitization stereotypy0.30.30.50.7-0.70.6-0.6-0.00.5-0.5-0.5-0.5-0.50.50.5-0.5-0.50.60.70.5-0.60.6-0.6-0.10.1-0.1
Conditioned locomotion3.44.05.1-2.32.3-2.22.2-2.2-2.01.92.01.91.9-1.9-1.91.81.8-1.9-1.9-1.81.9-1.91.92.0-2.0-2.3
Cocaine response after cond. corrected0.30.50.9-0.40.4-0.50.4-0.0-0.70.80.70.80.9-0.9-0.80.90.8-0.9-0.9-0.90.9-0.90.90.0-0.0-0.1
Cocaine response after cond. not corrected0.91.31.9-0.90.9-1.11.0-0.7-1.21.31.21.41.4-1.4-1.31.31.3-1.3-1.2-1.31.2-1.21.20.7-0.7-0.8
Cocaine response before conditioning2.02.44.7-1.81.8-1.72.0-2.2-1.51.51.51.41.4-1.4-1.41.21.4-1.1-1.1-1.20.8-0.80.82.1-2.1-2.1
Saline control response0.91.22.5-1.01.0-1.11.0-1.6-1.01.01.01.01.0-1.0-1.00.90.9-0.9-0.9-0.91.0-1.01.01.4-1.4-1.5
Bone: connectivity density3.45.57.7-1.21.2-2.01.4-1.8-2.52.72.52.82.8-2.8-2.62.62.7-2.6-2.7-2.62.6-2.62.61.8-1.8-1.8
Bone: cortical apparent density0.30.40.7-0.40.4-0.50.3-0.2-0.60.70.70.80.8-0.8-0.70.70.8-0.7-0.7-0.70.7-0.70.70.5-0.5-0.4
Bone: cortical area0.40.61.40.4-0.4-0.2-0.10.1-0.71.10.71.21.2-1.2-0.91.01.1-0.9-0.9-1.00.7-0.70.7-0.20.20.1
Bone: cortical porosity1.71.83.6-1.51.5-1.51.9-1.8-1.31.21.31.11.1-1.1-1.21.01.1-1.0-1.1-1.01.1-1.11.11.7-1.7-1.7
Bone: cortical porosity1.51.72.9-1.41.4-1.51.7-1.5-1.41.31.31.21.2-1.2-1.31.11.2-1.1-1.2-1.11.2-1.21.21.4-1.4-1.4
Bone: cortical thickness0.10.20.50.6-0.60.5-0.60.50.20.1-0.20.20.2-0.20.1-0.20.10.20.20.2-0.40.4-0.4-0.70.70.6
Bone: cortical thickness1.01.31.9-0.70.7-0.90.6-0.6-1.21.31.21.41.4-1.4-1.31.21.4-1.3-1.4-1.21.2-1.21.20.5-0.5-0.6
Bone: cortical tissue density0.20.20.5-0.30.3-0.30.2-0.0-0.50.60.50.70.7-0.7-0.60.50.7-0.6-0.6-0.50.5-0.50.50.3-0.3-0.3
Condit. Reinf. active minus inactive responses1.11.22.21.3-1.31.3-1.51.41.1-1.0-1.0-0.8-0.80.80.9-0.9-0.90.90.80.9-1.01.0-1.0-1.31.31.4
Condit. Reinf. active-inactive response ratio1.11.22.01.1-1.11.1-1.41.41.0-1.0-1.0-0.9-0.90.90.9-0.9-1.00.90.80.9-0.90.9-0.9-1.41.41.4
Condit. Reinf. active responses0.00.10.20.2-0.20.0-0.10.3-0.20.30.20.40.4-0.4-0.30.30.4-0.2-0.2-0.30.0-0.00.0-0.10.10.2
Condit. Reinf. inactive responses1.31.62.2-0.90.9-1.21.3-1.0-1.31.51.31.51.5-1.5-1.41.41.5-1.2-1.2-1.41.1-1.11.11.3-1.3-1.4
Incentive salience index mean0.10.10.50.5-0.50.3-0.60.70.10.0-0.10.10.1-0.1-0.0-0.00.1-0.1-0.10.0-0.10.1-0.1-0.60.60.7
Condit. Reinf. lever presses0.40.71.0-0.80.8-0.90.7-0.3-0.91.00.91.01.0-1.0-0.90.80.9-0.9-0.9-0.80.8-0.80.80.4-0.4-0.3
Condit. Reinf. active minus inactive responses3.14.88.7-1.41.4-2.02.2-2.9-2.22.22.22.12.1-2.1-2.22.02.1-2.0-2.0-2.01.9-1.91.93.0-3.0-2.9
Condit. Reinf. active-inactive response ratio1.01.54.8-0.80.8-1.11.4-2.1-1.11.11.11.01.0-1.0-1.00.91.0-0.8-0.8-0.90.8-0.80.82.0-2.0-2.2
Condit. Reinf. active responses2.84.06.3-1.11.1-1.81.9-2.3-2.02.12.02.02.0-2.0-2.12.02.0-2.0-2.0-2.02.0-2.02.02.5-2.5-2.3
Condit. Reinf. inactive responses1.01.52.5-0.50.5-1.10.7-0.5-1.31.41.31.41.4-1.4-1.41.51.4-1.6-1.6-1.51.5-1.51.50.8-0.8-0.5
Condit. Reinf. lever presses1.92.84.3-1.51.5-1.71.9-2.0-1.71.71.71.61.6-1.6-1.61.61.6-1.7-1.6-1.61.4-1.41.42.1-2.1-1.9
Condit. Reinf. lever reinforcers received2.73.76.1-1.11.1-1.71.8-2.3-1.92.01.91.91.9-1.9-2.01.91.9-1.9-1.9-1.91.8-1.81.82.5-2.5-2.3
Conditioned reinforcement - actives1.04.110.6-3.33.3-2.52.8-2.5-1.91.41.81.21.2-1.2-1.51.81.2-1.8-1.8-1.71.9-1.91.91.9-1.9-2.0
Conditioned reinforcement - inactives1.64.58.7-3.03.0-2.41.8-1.8-2.22.02.22.02.0-2.0-2.11.91.9-2.0-1.9-2.12.0-2.02.02.0-2.0-2.0
Conditioned locomotion0.71.13.1-1.81.8-1.41.5-1.5-0.80.30.80.20.2-0.2-0.51.00.2-0.8-0.8-0.71.0-1.01.01.1-1.1-1.3
Patch foraging indifference point 0 sec0.30.92.41.5-1.51.1-1.10.91.0-0.8-0.9-0.7-0.70.70.9-1.0-0.80.90.71.1-0.70.7-0.7-0.80.80.8
Patch foraging indifference point AUC0.51.22.7-0.10.1-0.60.0-0.1-1.11.41.21.61.6-1.6-1.41.31.6-1.2-1.1-1.21.1-1.11.10.4-0.4-0.5
Delay disc. indifference point, 0s delay3.03.45.01.1-1.11.6-1.32.11.9-1.9-1.9-1.8-1.81.81.9-1.7-1.91.82.01.7-2.02.0-2.0-2.22.22.2
Delay disc. indifference point, 16s delay0.00.10.40.1-0.1-0.10.6-0.3-0.20.20.20.10.1-0.1-0.20.40.2-0.10.0-0.20.1-0.10.10.3-0.3-0.1
Delay disc. indifference point, 2s delay0.20.20.50.4-0.40.4-0.20.50.4-0.4-0.4-0.4-0.40.40.4-0.2-0.40.30.50.2-0.60.6-0.6-0.70.70.7
Delay disc. indifference point, 24s delay0.61.03.1-1.51.5-1.21.8-1.0-1.00.81.00.70.7-0.7-0.91.10.8-1.0-0.7-0.90.8-0.80.80.6-0.6-0.4
Delay disc. indifference point, 4s delay0.00.00.20.2-0.20.2-0.20.50.00.1-0.00.10.1-0.1-0.10.30.1-0.10.1-0.2-0.10.1-0.1-0.20.20.2
Delay disc. indifference point, 8s delay0.00.00.2-0.30.3-0.20.3-0.1-0.10.00.1-0.0-0.00.0-0.10.40.0-0.3-0.1-0.20.1-0.10.1-0.00.00.2
Indifference point function ln k0.10.31.4-1.21.2-0.81.1-1.0-0.40.20.30.00.0-0.0-0.10.2-0.0-0.3-0.3-0.30.3-0.30.30.7-0.7-0.5
Indifference point function log k0.10.31.4-1.21.2-0.81.1-1.0-0.40.20.30.00.0-0.0-0.10.2-0.0-0.3-0.3-0.30.3-0.30.30.7-0.7-0.5
Patch foraging total patch changes 0 sec0.30.92.51.6-1.61.2-1.21.01.0-0.8-0.9-0.7-0.70.70.8-1.0-0.80.80.71.0-0.70.7-0.7-0.70.70.7
Patch foraging total patch changes 12 sec1.21.72.71.5-1.51.4-1.61.61.3-1.2-1.2-1.1-1.11.11.1-1.3-1.11.31.21.4-1.21.2-1.2-1.31.31.2
Patch foraging total patch changes 18 sec0.20.52.31.5-1.50.9-1.30.90.5-0.2-0.5-0.1-0.10.10.3-0.4-0.10.30.20.4-0.20.2-0.2-0.60.60.6
Patch foraging total patch changes 24 sec0.41.32.11.5-1.51.3-1.21.21.2-1.1-1.1-1.1-1.11.11.1-1.2-1.01.21.01.3-1.11.1-1.1-0.90.90.7
Patch foraging total patch changes 6 sec0.50.83.81.9-1.91.2-1.41.10.7-0.5-0.6-0.4-0.40.40.4-0.6-0.30.60.50.8-0.50.5-0.5-0.80.80.9
Patch foraging time to switch 0 sec0.00.10.70.6-0.60.4-0.80.30.3-0.4-0.3-0.4-0.40.40.20.1-0.30.10.2-0.0-0.20.2-0.2-0.10.1-0.0
Patch foraging water rate 0 sec0.10.21.2-0.80.8-0.61.1-0.9-0.30.40.30.30.2-0.2-0.20.10.2-0.2-0.2-0.00.2-0.20.20.4-0.4-0.6
Patch foraging water rate 12 sec0.31.42.40.0-0.00.7-0.10.41.2-1.3-1.2-1.5-1.51.51.4-1.5-1.41.41.31.5-1.31.3-1.3-0.90.90.8
Patch foraging water rate 18 sec0.30.61.0-0.90.9-0.11.0-0.50.5-0.8-0.6-1.0-1.01.00.8-0.9-1.00.91.00.7-0.90.9-0.9-0.10.10.2
Patch foraging water rate 24 sec1.52.13.80.4-0.41.0-1.00.81.5-1.8-1.5-1.9-1.91.91.7-1.6-1.81.61.41.7-1.51.5-1.5-1.01.01.0
Patch foraging water rate 6 sec0.81.21.8-0.30.30.50.30.31.0-1.2-1.1-1.3-1.31.31.3-1.3-1.31.31.31.2-1.41.4-1.4-0.90.90.7
Seeking ratio, delayed vs. immediate footshock0.00.00.20.5-0.50.20.0-0.10.1-0.1-0.1-0.1-0.10.10.1-0.2-0.20.10.20.0-0.20.2-0.20.2-0.2-0.0
Distance traveled before self-admin0.00.10.6-0.70.7-0.20.8-0.2-0.00.1-0.0-0.0-0.00.00.1-0.00.10.10.20.1-0.20.2-0.2-0.40.40.2
Distance traveled after self-admin1.32.44.30.8-0.81.5-1.11.71.5-1.4-1.6-1.4-1.41.41.5-1.7-1.31.61.61.6-1.61.6-1.6-2.12.11.8
Extensor digitorum longus weight4.116.218.4-2.82.8-3.83.4-4.1-4.14.34.24.24.2-4.2-4.24.34.2-4.2-4.1-4.34.0-4.04.04.1-4.1-4.3
Bone: elastic displacement0.91.12.7-1.61.6-1.31.6-0.9-1.00.80.90.70.7-0.7-0.80.70.7-0.9-1.1-0.71.3-1.31.30.9-0.9-1.0
Bone: elastic work0.91.21.8-1.11.1-1.11.3-0.7-1.11.11.11.11.1-1.1-1.11.11.0-1.2-1.3-1.11.4-1.41.40.5-0.5-0.6
Bone: endosteal estimation0.51.12.2-0.30.3-0.80.2-0.1-1.11.21.11.31.3-1.3-1.21.51.3-1.4-1.3-1.51.3-1.31.30.2-0.2-0.1
Bone: endosteal perimeter0.20.41.1-0.00.0-0.40.20.1-0.60.80.60.80.8-0.8-0.81.00.8-1.0-0.8-1.00.7-0.70.7-0.10.10.1
Epididymis fat weight11.055.763.57.5-7.57.8-7.57.67.9-8.0-7.7-7.8-7.87.87.7-7.0-7.77.27.17.2-7.27.2-7.2-6.96.97.0
Delta time in closed arm before/after self-admin0.10.10.90.5-0.50.3-1.00.30.1-0.0-0.00.10.1-0.1-0.10.20.2-0.3-0.2-0.40.3-0.30.3-0.20.20.2
Delta time in open arm before/after self-admin0.10.20.6-0.10.1-0.30.2-0.2-0.30.30.40.30.3-0.3-0.40.40.2-0.3-0.4-0.30.4-0.40.40.8-0.8-0.5
Diff in mean of infusions in LGA sessions0.00.10.20.5-0.50.1-0.30.2-0.0-0.00.1-0.0-0.00.0-0.10.20.2-0.2-0.4-0.00.4-0.40.40.2-0.2-0.2
Delay discount exponential model param0.20.20.70.4-0.40.5-0.60.30.5-0.5-0.5-0.5-0.50.50.5-0.9-0.50.60.40.7-0.40.4-0.4-0.30.30.1
Extinction: sum of active levers before priming0.20.30.5-0.50.5-0.5-0.3-0.1-0.50.30.50.40.4-0.4-0.50.50.6-0.6-0.6-0.50.5-0.50.50.6-0.6-0.7
Active lever presses in extinction session 60.80.91.5-1.21.2-1.20.8-1.0-1.00.61.00.50.5-0.5-0.81.00.7-0.9-1.0-0.81.0-1.01.01.0-1.0-1.0
Bone: final force0.10.10.30.3-0.3-0.0-0.10.3-0.30.40.30.50.5-0.5-0.40.50.5-0.5-0.5-0.50.2-0.20.2-0.30.30.4
Bone: final moment0.10.20.40.2-0.2-0.1-0.00.3-0.30.50.30.60.6-0.6-0.50.50.5-0.5-0.5-0.50.3-0.30.3-0.40.40.4
Food consumed during 24 hour testing period0.10.20.30.2-0.2-0.1-0.0-0.2-0.40.50.40.60.6-0.6-0.40.40.6-0.3-0.4-0.40.3-0.30.30.3-0.3-0.3
Glucose0.30.51.61.3-1.30.9-1.00.80.7-0.6-0.7-0.6-0.50.50.6-0.5-0.50.50.50.5-0.40.4-0.4-0.80.80.7
Heart weight2.94.66.21.5-1.52.1-2.02.32.1-2.0-2.2-1.9-1.91.92.1-2.2-1.92.32.52.0-2.52.5-2.5-2.42.42.2
Delay discount hyperbolic model param0.10.10.50.1-0.10.3-0.30.00.3-0.3-0.3-0.4-0.40.40.4-0.7-0.40.50.30.6-0.30.3-0.3-0.10.1-0.1
Intermittent access intake day 1-15 change0.10.31.1-1.11.1-0.70.8-0.8-0.50.40.50.30.3-0.3-0.30.50.6-0.4-0.3-0.40.4-0.40.40.2-0.2-0.5
Intermittent access intake escalation0.00.10.5-0.70.7-0.40.5-0.4-0.20.10.20.00.0-0.0-0.00.20.3-0.00.0-0.10.0-0.00.0-0.10.1-0.1
Intermittent access intake escalation 20.00.00.1-0.20.2-0.1-0.0-0.2-0.10.20.10.20.2-0.2-0.1-0.00.40.10.2-0.2-0.10.1-0.1-0.10.10.1
Intermitt. access day 1 inactive lever presses0.11.83.3-1.11.1-1.31.3-1.5-1.31.31.31.31.3-1.3-1.31.31.1-1.2-1.3-1.21.3-1.31.31.6-1.6-1.8
Intermitt. access day 15 inactive lever presses1.26.69.9-1.51.5-2.11.7-2.0-2.73.02.73.13.1-3.1-2.92.82.9-2.5-2.5-2.62.6-2.62.62.7-2.7-2.5
Intermitt. access escalation Index0.51.78.02.7-2.71.8-2.81.71.0-0.6-0.9-0.4-0.40.40.6-1.1-0.30.80.81.0-0.80.8-0.8-0.80.80.9
Intermittent access day 1 total infusions1.85.46.6-2.62.6-2.52.5-2.5-2.42.22.42.12.1-2.1-2.32.42.0-2.2-2.2-2.02.3-2.32.32.5-2.5-2.4
Intermittent access day 15 total infusions1.12.64.8-2.22.2-1.91.9-1.9-1.71.51.71.41.4-1.4-1.61.61.5-1.4-1.4-1.31.5-1.51.51.5-1.5-1.6
Intermittent access terminal intake (last 3 days)2.13.76.8-2.62.6-2.22.4-2.2-2.01.81.91.71.7-1.7-1.81.81.8-1.7-1.6-1.61.7-1.71.71.8-1.8-1.9
Intermittent access total infusions3.23.78.0-2.82.8-2.32.5-2.4-1.91.51.81.41.4-1.4-1.62.01.3-1.7-1.7-1.61.8-1.81.81.9-1.9-1.9
Intermittent access day 1 locomotion1.42.53.9-1.91.9-1.81.8-1.7-1.61.31.61.31.3-1.3-1.51.61.3-1.4-1.4-1.31.5-1.51.51.9-1.9-2.0
Intermittent access day 15 total locomotion0.10.51.0-1.01.0-0.70.6-0.7-0.60.50.60.50.5-0.5-0.60.80.4-0.7-0.6-0.70.6-0.60.60.8-0.8-1.0
Intermittent access total locomotion0.70.92.8-1.71.7-1.21.0-1.0-0.80.30.80.30.3-0.3-0.61.00.3-0.8-0.8-0.70.8-0.80.81.1-1.1-1.4
Intermittent access standard deviation0.41.93.1-1.61.6-1.51.8-1.4-1.41.21.41.21.2-1.2-1.31.41.2-1.3-1.3-1.21.4-1.41.41.4-1.4-1.3
Left kidney weight0.00.10.1-0.40.4-0.10.20.10.1-0.3-0.1-0.3-0.40.40.2-0.0-0.30.10.20.1-0.30.3-0.3-0.10.10.2
Right kidney weight0.32.12.90.7-0.71.2-0.91.51.4-1.6-1.5-1.6-1.61.61.5-1.4-1.51.51.71.3-1.71.7-1.7-1.51.51.5
Cocaine induced anxiety0.10.20.5-0.10.1-0.3-0.4-0.1-0.50.50.50.60.6-0.6-0.60.50.7-0.5-0.5-0.50.5-0.50.50.5-0.5-0.5
Post-drug Anxiety1.41.62.41.4-1.41.4-1.41.61.3-1.2-1.2-1.2-1.21.21.2-1.1-1.11.21.21.2-1.31.3-1.3-1.21.21.3
Baseline Anxiety2.33.84.61.9-1.92.0-1.31.92.1-2.0-2.1-2.0-2.02.02.0-1.8-2.22.01.92.1-1.91.9-1.9-1.91.92.0
Tail length0.31.42.30.2-0.20.8-0.31.01.1-1.4-1.1-1.4-1.41.41.2-1.0-1.31.21.31.0-1.31.3-1.3-1.51.51.5
Length with tail1.56.69.41.1-1.12.0-1.32.22.6-2.9-2.6-3.1-3.13.12.8-2.5-2.92.72.72.5-2.72.7-2.7-2.82.82.8
Length without tail0.31.72.70.9-0.91.1-0.81.31.3-1.4-1.4-1.4-1.41.41.4-1.2-1.51.31.21.2-1.31.3-1.3-1.61.61.6
Times rat made contact with spout1.61.82.5-0.80.8-1.10.7-1.2-1.41.51.41.51.5-1.5-1.41.51.5-1.5-1.6-1.51.5-1.51.51.3-1.3-1.3
Lifetime Intake3.44.28.7-2.92.9-2.42.4-2.3-2.01.72.01.51.5-1.5-1.72.11.4-1.9-1.9-1.81.9-1.91.92.1-2.1-2.1
Liver weight, left3.66.37.51.9-1.92.3-2.22.62.5-2.5-2.5-2.5-2.52.52.5-2.5-2.62.62.62.5-2.72.7-2.7-2.62.62.7
Liver weight, right8.915.519.62.5-2.53.6-3.23.84.0-4.3-4.1-4.2-4.24.24.1-4.2-4.24.34.44.1-4.34.3-4.3-3.53.53.5
Locomotor activity0.40.71.71.0-1.01.0-1.31.30.8-0.8-0.8-0.7-0.70.70.7-0.7-0.80.70.60.7-0.70.7-0.7-0.70.70.8
Locomotor testing distance0.10.20.80.6-0.60.1-0.90.3-0.20.30.20.40.4-0.4-0.40.30.4-0.4-0.5-0.30.6-0.60.60.5-0.5-0.2
Locomotor testing rearing0.31.22.4-0.50.5-1.00.3-0.9-1.00.81.00.80.8-0.8-1.01.20.9-1.3-1.5-1.11.5-1.51.51.5-1.5-1.3
Locomotion in novel chamber0.10.10.30.1-0.10.1-0.1-0.00.3-0.4-0.2-0.4-0.40.40.3-0.1-0.60.20.20.4-0.20.2-0.20.2-0.2-0.1
Locomotion in novel chamber post-restriction1.64.86.12.2-2.22.2-2.22.02.3-2.5-2.2-2.5-2.42.42.2-2.2-2.42.22.02.3-1.91.9-1.9-2.02.01.7
Fecal boli incidents, locomotor time 10.20.62.2-1.51.5-1.01.1-1.0-0.80.70.70.60.6-0.6-0.60.40.6-0.3-0.4-0.40.6-0.60.60.5-0.5-0.9
Change in fecal boli incidents, locomotor task4.04.35.41.9-1.92.1-1.92.32.2-2.2-2.1-2.1-2.12.12.1-2.1-2.12.02.02.1-2.02.0-2.0-2.22.22.3
Time >=10cm from walls, locomotor time 10.10.10.7-0.90.9-0.20.5-0.00.1-0.2-0.2-0.3-0.30.30.3-0.4-0.30.20.40.4-0.40.4-0.4-0.30.30.1
Bouts of movement, locomotor time 11.31.63.00.3-0.3-0.70.5-1.2-1.21.61.21.61.6-1.6-1.41.71.5-1.4-1.3-1.71.2-1.21.21.2-1.2-1.0
Total resting periods, locomotor time 11.71.93.30.2-0.2-0.80.7-1.3-1.31.71.41.71.7-1.7-1.51.81.6-1.5-1.5-1.81.4-1.41.41.3-1.3-1.0
Rest time, locomotor task time 10.00.10.30.5-0.50.30.20.10.2-0.2-0.2-0.2-0.20.20.2-0.2-0.20.20.20.2-0.10.1-0.1-0.30.30.6
Distance moved, locomotor task time 10.41.11.70.1-0.10.8-1.01.21.0-1.2-1.1-1.2-1.21.21.1-1.3-1.11.21.21.2-1.21.2-1.2-0.80.80.7
Vertical activity count, locomotor time 10.10.50.80.2-0.20.5-0.70.90.7-0.7-0.7-0.7-0.70.70.7-0.9-0.70.80.80.9-0.90.9-0.9-0.60.60.7
Time >=10cm from walls, locomotor time 20.20.62.3-1.51.5-1.11.3-0.7-0.70.60.70.50.5-0.5-0.50.70.4-0.8-0.5-0.70.4-0.40.40.3-0.3-0.9
Bouts of movement, locomotor time 20.00.20.60.8-0.80.6-0.30.10.4-0.2-0.3-0.1-0.10.10.30.0-0.20.10.40.1-0.40.4-0.4-0.40.40.4
Total resting periods, locomotor time 20.00.10.70.9-0.90.4-0.1-0.20.10.2-0.00.20.2-0.2-0.10.40.2-0.30.1-0.3-0.00.0-0.0-0.10.10.1
Rest time, locomotor task time 20.71.11.70.1-0.1-0.60.8-0.9-1.01.21.11.31.3-1.3-1.21.31.3-1.2-1.1-1.21.2-1.21.20.9-0.9-0.7
Distance moved, locomotor task time 20.70.91.4-0.20.20.5-0.61.10.9-1.2-0.9-1.2-1.21.21.1-1.1-1.11.11.11.0-1.11.1-1.1-0.80.80.6
Vertical activity count, locomotor time 20.20.40.7-0.40.40.2-0.40.60.6-0.8-0.6-0.8-0.80.80.7-0.7-0.80.60.70.6-0.80.8-0.8-0.50.50.6
Light reinforcement 11.25.38.4-0.30.3-1.60.9-1.8-2.32.82.42.92.9-2.9-2.62.62.9-2.5-2.4-2.62.3-2.32.32.3-2.3-1.8
Light reinforcement 21.63.65.7-1.01.0-1.61.5-1.7-2.02.32.02.42.3-2.3-2.12.02.4-2.0-1.9-2.21.8-1.81.81.5-1.5-1.5
Bone: marrow area0.51.12.2-0.30.3-0.80.2-0.1-1.11.21.11.31.3-1.3-1.21.51.3-1.4-1.3-1.51.3-1.31.30.2-0.2-0.1
Bone: maximum diameter0.71.52.80.1-0.1-0.6-0.1-0.1-1.21.51.21.71.7-1.7-1.51.71.6-1.6-1.5-1.71.3-1.31.30.1-0.1-0.1
Bone: maximum force0.10.20.40.0-0.0-0.30.3-0.0-0.40.60.40.60.6-0.6-0.50.60.6-0.6-0.6-0.60.4-0.40.40.0-0.00.0
Bone: maximum moment0.20.30.6-0.10.1-0.30.4-0.0-0.50.70.50.80.8-0.8-0.60.70.7-0.7-0.7-0.70.5-0.50.50.0-0.0-0.0
Mean time between licks in bursts0.63.74.41.3-1.31.8-1.92.01.9-2.0-2.0-1.9-1.91.92.0-2.1-1.92.12.02.1-2.02.0-2.0-1.91.91.9
Mean num. licks in bursts0.20.51.6-1.11.1-1.01.3-1.2-0.70.50.60.40.4-0.4-0.50.40.4-0.4-0.6-0.40.7-0.70.70.7-0.7-0.7
Cd content in liver0.00.00.20.3-0.30.1-0.40.20.00.00.00.00.0-0.0-0.00.00.1-0.1-0.1-0.00.1-0.10.1-0.10.10.0
Co content in liver5.66.67.9-2.52.5-2.62.4-2.3-2.72.82.62.82.8-2.8-2.72.72.7-2.7-2.6-2.72.5-2.52.52.1-2.1-2.1
Cu content in liver0.20.20.7-0.80.8-0.60.8-0.3-0.40.40.40.30.3-0.3-0.30.30.4-0.3-0.3-0.30.2-0.20.20.4-0.4-0.4
Fe content in liver1.11.42.9-1.51.5-1.51.7-0.9-1.21.01.21.01.0-1.0-1.10.91.0-1.0-1.2-0.91.2-1.21.21.3-1.3-1.0
K content in liver0.40.40.80.5-0.50.1-0.30.6-0.40.70.40.90.9-0.9-0.60.70.9-0.6-0.4-0.70.4-0.40.4-0.60.60.8
Mg content in liver0.40.40.80.5-0.50.1-0.30.7-0.40.70.40.90.9-0.9-0.60.70.9-0.6-0.5-0.70.4-0.40.4-0.60.60.7
Mn content in liver0.30.41.91.4-1.40.5-1.20.60.00.10.00.30.3-0.3-0.20.40.3-0.4-0.5-0.40.5-0.50.5-0.50.50.6
Na content in liver0.80.92.9-1.71.7-1.21.6-0.8-1.00.80.90.80.8-0.8-0.80.70.9-0.6-0.5-0.70.5-0.50.50.7-0.7-0.6
Rb content in liver0.10.10.60.5-0.50.3-0.80.70.1-0.0-0.10.10.1-0.1-0.10.00.1-0.0-0.1-0.00.0-0.00.0-0.60.60.6
Se content in liver0.10.10.30.6-0.60.4-0.40.50.3-0.4-0.3-0.4-0.40.40.3-0.2-0.30.20.20.2-0.10.1-0.1-0.10.10.0
Sr content in liver0.20.20.3-0.60.60.00.50.10.2-0.3-0.3-0.4-0.40.40.4-0.4-0.40.50.50.4-0.50.5-0.5-0.30.30.3
Zn content in liver0.91.02.30.9-0.91.1-0.71.51.0-0.8-1.0-0.8-0.80.80.9-0.9-0.80.91.00.9-1.01.0-1.0-1.41.41.5
Bone: minimum diameter0.20.41.41.0-1.00.8-1.11.10.4-0.2-0.4-0.1-0.10.10.2-0.1-0.10.10.20.1-0.30.3-0.3-1.21.21.2
Time in familiar zone, hab. session 10.80.82.01.1-1.11.0-1.41.30.9-0.8-0.8-0.7-0.70.70.8-0.7-0.70.70.70.7-0.70.7-0.7-1.21.21.2
Time in novel zone, hab. session 10.30.40.90.4-0.40.5-0.3-0.20.7-0.9-0.6-0.9-0.90.90.8-0.7-0.90.60.40.7-0.50.5-0.50.0-0.00.0
Total zone transitions, hab. session 10.10.20.5-0.20.2-0.30.3-0.5-0.40.40.40.40.4-0.4-0.40.40.4-0.4-0.5-0.40.3-0.30.30.7-0.7-0.5
Total locomotion distance, hab. session 10.20.30.8-0.90.9-0.60.3-0.2-0.50.60.50.50.5-0.5-0.50.60.5-0.5-0.5-0.60.4-0.40.40.4-0.4-0.2
Locomotion velocity, hab. session 10.91.32.0-1.41.4-1.21.0-0.8-1.21.31.21.31.3-1.3-1.21.11.3-1.1-1.2-1.11.0-1.01.00.9-0.9-0.8
Time in familiar zone, hab. session 20.10.10.40.6-0.60.3-0.40.00.00.1-0.00.10.1-0.1-0.10.20.1-0.2-0.2-0.20.2-0.20.2-0.00.0-0.1
Time in novel zone, hab. session 20.40.50.7-0.00.00.4-0.40.70.6-0.8-0.7-0.8-0.80.80.7-0.8-0.80.80.70.8-0.80.8-0.8-0.70.70.8
Total zone transitions, hab. session 20.10.10.70.9-0.90.2-0.20.2-0.10.30.10.40.4-0.4-0.20.30.4-0.3-0.3-0.30.2-0.20.2-0.20.20.3
Total locomotion distance, hab. session 20.10.20.40.7-0.70.1-0.1-0.0-0.20.50.30.60.6-0.6-0.40.40.6-0.4-0.3-0.40.2-0.20.20.0-0.00.1
Locomotion velocity, hab. session 20.20.30.60.5-0.5-0.10.1-0.2-0.40.70.50.80.8-0.8-0.60.60.8-0.5-0.5-0.60.4-0.40.40.3-0.3-0.1
Novel to familiar place preference ratio0.91.21.50.9-0.91.1-1.10.91.1-1.1-1.1-1.1-1.11.11.1-1.1-1.11.11.11.1-1.21.2-1.2-1.01.01.1
Novelty place preference1.41.82.11.1-1.11.3-1.41.11.4-1.4-1.4-1.4-1.41.41.4-1.4-1.41.41.41.4-1.41.4-1.4-1.21.21.3
Time in novel zone, NPP test1.61.92.31.1-1.11.3-1.41.11.4-1.5-1.4-1.5-1.51.51.5-1.5-1.51.41.41.5-1.51.5-1.5-1.21.21.3
Total zone transitions, NPP test1.21.82.5-0.90.9-1.31.5-1.2-1.41.61.41.51.5-1.5-1.41.21.5-1.3-1.3-1.21.2-1.21.21.4-1.4-1.3
Total locomotion distance, NPP test1.72.43.0-1.11.1-1.51.5-1.6-1.61.71.61.71.7-1.7-1.61.51.7-1.5-1.5-1.51.4-1.41.41.6-1.6-1.5
Locomotion velocity, NPP test2.73.94.9-1.31.3-1.81.8-1.8-2.02.22.02.22.2-2.2-2.12.02.2-2.0-2.0-2.02.0-2.02.01.9-1.9-1.8
Intraocular pressure5.38.611.52.5-2.53.0-3.43.13.1-3.1-3.0-2.9-2.92.93.0-2.9-3.12.92.83.0-2.82.8-2.8-2.92.93.0
Delta distance traveled before/after self-admin1.81.93.01.5-1.51.6-1.71.61.4-1.2-1.4-1.1-1.11.11.3-1.5-1.21.41.31.4-1.41.4-1.4-1.41.41.3
Delta ambulatory time before/after self-admin0.20.41.51.0-1.00.8-1.21.00.6-0.3-0.5-0.2-0.20.20.4-0.6-0.30.50.40.5-0.50.5-0.5-0.70.70.7
Parametrial fat weight12.930.440.06.3-6.36.3-5.55.85.7-5.0-5.6-4.8-4.84.85.3-5.3-4.95.45.65.2-5.75.7-5.7-5.65.65.6
Pavlov. Cond. lever latency1.31.62.60.6-0.61.1-0.70.71.3-1.5-1.3-1.6-1.61.61.5-1.4-1.61.41.31.4-1.31.3-1.3-1.01.00.7
Pavlov. Cond. magazine entry latency0.10.10.20.4-0.4-0.0-0.40.1-0.20.30.20.40.4-0.4-0.30.20.4-0.2-0.2-0.20.1-0.10.10.0-0.00.1
Pavlov. Cond. change in total contacts0.00.00.1-0.10.1-0.1-0.20.1-0.20.20.20.30.3-0.3-0.20.10.2-0.1-0.1-0.10.1-0.10.10.1-0.10.2
Pavlov. Cond. index score0.40.51.20.1-0.1-0.5-0.1-0.1-0.81.00.81.11.1-1.1-0.90.81.1-0.8-0.8-0.80.7-0.70.70.4-0.4-0.1
Pavlov. Cond. latency score0.40.61.20.2-0.2-0.4-0.2-0.1-0.71.00.81.11.1-1.1-0.90.81.1-0.8-0.8-0.80.7-0.70.70.4-0.4-0.1
Pavlov. Cond. lever contacts0.81.01.7-0.50.5-0.90.5-0.5-1.11.21.11.31.3-1.3-1.11.11.3-1.1-1.0-1.11.0-1.01.00.7-0.7-0.3
Pavlov. Cond. magazine entry number0.30.30.8-0.10.10.40.20.20.6-0.8-0.6-0.9-0.90.90.8-0.6-0.90.60.60.6-0.50.5-0.5-0.30.30.1
Pavlov. Cond. intertrial magazine entries1.51.83.2-1.81.8-1.51.8-1.2-1.31.21.31.21.2-1.2-1.21.21.2-1.1-1.1-1.21.2-1.21.21.6-1.6-1.6
Pavlov. Cond. lever-magazine prob. diff.0.91.12.1-0.40.4-0.90.3-0.6-1.21.41.21.41.4-1.4-1.31.21.4-1.2-1.2-1.21.1-1.11.10.8-0.8-0.5
Pavlov. Cond. response bias1.01.22.0-0.70.7-1.10.6-0.7-1.21.41.21.41.4-1.4-1.31.11.4-1.1-1.1-1.11.1-1.11.10.8-0.8-0.6
Pavlov. Cond. lever latency1.42.03.11.2-1.21.3-1.51.51.4-1.4-1.4-1.3-1.31.31.4-1.5-1.41.51.51.5-1.11.1-1.1-1.81.81.5
Pavlov. Cond. magazine entry latency0.20.30.5-0.20.2-0.40.5-0.5-0.50.60.50.60.6-0.6-0.60.60.6-0.7-0.7-0.60.4-0.40.40.6-0.6-0.5
Pavlov. Cond. change in total contacts0.41.01.9-0.50.5-0.80.9-1.2-0.91.00.90.90.9-0.9-0.91.00.9-1.2-1.2-1.00.9-0.90.91.4-1.4-1.2
Pavlov. Cond. index score1.01.52.2-1.01.0-1.11.3-1.3-1.21.31.21.21.2-1.2-1.21.31.2-1.4-1.4-1.31.0-1.01.01.5-1.5-1.3
Pavlov. Cond. latency score1.01.62.3-1.01.0-1.11.4-1.4-1.21.31.31.21.2-1.2-1.21.31.3-1.5-1.4-1.31.1-1.11.11.5-1.5-1.4
Pavlov. Cond. lever contacts0.91.42.3-1.01.0-1.11.3-1.2-1.11.11.21.11.1-1.1-1.11.31.1-1.3-1.2-1.30.9-0.90.91.5-1.5-1.3
Pavlov. Cond. magazine entry number0.10.20.40.1-0.10.2-0.30.20.4-0.5-0.4-0.5-0.50.50.4-0.5-0.50.60.60.5-0.30.3-0.3-0.60.60.4
Pavlov. Cond. intertrial magazine entries2.45.36.12.1-2.12.3-2.22.02.4-2.5-2.4-2.4-2.42.42.4-2.3-2.42.42.52.3-2.22.2-2.2-2.32.32.2
Pavlov. Cond. lever-magazine prob. diff.0.61.01.4-0.60.6-0.81.0-1.0-1.01.01.01.01.0-1.0-1.01.11.0-1.2-1.2-1.10.8-0.80.81.2-1.2-1.0
Pavlov. Cond. response bias1.62.23.3-1.21.2-1.41.6-1.5-1.51.51.51.51.5-1.5-1.51.61.5-1.6-1.5-1.61.1-1.11.11.8-1.8-1.5
Time in closed arm before self-admin0.40.81.40.7-0.70.8-0.80.81.0-1.0-0.9-1.1-1.11.11.0-0.8-1.20.80.70.8-0.80.8-0.8-1.01.00.3
Time in closed arm after self-admin1.01.11.90.9-0.91.0-1.40.91.2-1.3-1.1-1.3-1.31.31.2-1.0-1.40.90.80.9-0.80.8-0.8-1.21.20.5
Time in open arm before self-admin0.00.00.20.1-0.1-0.00.0-0.1-0.20.20.10.20.2-0.2-0.20.20.4-0.10.0-0.20.1-0.10.1-0.00.00.0
Time in open arm after self-admin1.11.21.8-0.60.6-0.90.6-0.8-1.21.21.21.31.3-1.3-1.31.21.4-1.1-1.0-1.11.0-1.01.01.3-1.3-1.0
Bone: periosteal estimation0.71.62.9-0.30.3-0.80.2-0.2-1.31.61.31.71.7-1.7-1.51.71.6-1.6-1.4-1.71.3-1.31.30.2-0.2-0.1
Bone: periosteal perimeter0.30.51.1-0.00.0-0.40.2-0.0-0.70.90.71.01.0-1.0-0.91.01.0-1.0-0.8-1.00.7-0.70.70.0-0.0-0.0
Bone: post-yield work1.01.72.6-1.41.4-1.51.5-1.5-1.31.21.31.11.1-1.1-1.21.11.1-1.2-1.3-1.11.3-1.31.31.6-1.6-1.6
Progressive ratio test 1 active lever presses1.42.45.5-2.32.3-1.92.0-1.7-1.51.11.51.01.0-1.0-1.31.71.0-1.5-1.4-1.51.5-1.51.51.7-1.7-1.4
Progressive ratio test 1 breakpoint1.42.55.5-2.42.4-1.92.0-1.7-1.51.11.51.01.0-1.0-1.31.70.9-1.5-1.4-1.51.5-1.51.51.7-1.7-1.4
Progressive ratio test 1 inactive lever presses2.15.49.7-3.13.1-2.62.4-2.4-2.42.02.31.91.9-1.9-2.22.31.9-2.1-2.1-2.12.2-2.22.22.4-2.4-2.5
Progressive ratio test 2 active lever presses0.71.15.1-2.32.3-1.41.6-1.3-0.90.50.80.30.3-0.3-0.60.70.3-0.7-0.6-0.60.7-0.70.70.8-0.8-0.7
Progressive ratio test 2 breakpoint0.70.94.7-2.22.2-1.31.5-1.2-0.80.40.70.20.2-0.2-0.50.60.2-0.5-0.5-0.50.6-0.60.60.7-0.7-0.6
Progressive ratio test 2 inactive lever presses0.92.96.2-2.52.5-2.01.8-1.8-1.71.51.71.41.4-1.4-1.51.81.4-1.6-1.6-1.61.5-1.51.51.7-1.7-1.7
Incentive Sensitization - Responses0.10.42.1-1.41.4-0.90.9-0.7-0.60.40.60.40.4-0.4-0.40.30.5-0.3-0.3-0.20.4-0.40.40.3-0.3-0.4
Incentive Sensitization - Breakpoint0.10.21.5-1.21.2-0.80.7-0.6-0.40.30.40.30.3-0.3-0.30.10.4-0.1-0.2-0.00.2-0.20.20.1-0.1-0.2
Sum of active levers in priming session hrs 5-60.30.30.60.6-0.60.1-0.70.5-0.40.60.40.80.8-0.8-0.60.30.8-0.4-0.4-0.50.3-0.30.30.3-0.3-0.1
Progressive ratio0.00.00.20.3-0.30.2-0.40.20.1-0.1-0.1-0.0-0.00.00.10.1-0.30.0-0.00.0-0.00.0-0.0-0.20.20.1
Food seeking constrained by brief footshock4.96.111.8-3.43.4-3.12.8-2.8-2.52.22.42.02.0-2.0-2.22.02.0-2.1-2.3-2.02.3-2.32.32.7-2.7-2.5
Seeking ratio, punishment vs. effort0.30.72.0-1.41.4-1.11.3-1.0-0.90.70.80.60.6-0.6-0.70.40.9-0.6-0.6-0.50.7-0.70.71.0-1.0-0.7
Retroperitoneal fat weight22.9102.5140.611.9-11.911.3-11.310.710.6-10.0-10.3-9.7-9.79.79.9-9.5-9.79.69.69.5-9.59.5-9.5-9.59.59.8
Reaction time number correct0.20.71.2-0.40.4-0.70.7-0.9-0.81.10.81.11.0-1.0-0.90.71.0-0.8-0.8-0.70.8-0.80.80.9-0.9-0.7
Reaction time mean minus median0.00.10.3-0.50.5-0.30.3-0.4-0.1-0.00.1-0.1-0.10.10.0-0.0-0.1-0.0-0.0-0.10.2-0.20.20.5-0.5-0.5
Reaction time mean minus median AUC0.00.00.1-0.00.00.1-0.10.10.2-0.2-0.2-0.2-0.30.30.3-0.4-0.40.30.30.2-0.10.1-0.10.1-0.1-0.1
Reaction time num false alarms0.40.64.02.0-2.01.1-1.61.00.5-0.1-0.40.10.1-0.10.1-0.30.00.20.10.3-0.20.2-0.2-0.60.60.8
Reaction time num false alarms AUC0.30.74.22.0-2.01.2-1.61.10.5-0.1-0.40.10.1-0.10.1-0.30.00.20.10.3-0.20.2-0.2-0.50.50.7
Reaction time trials correct on left0.20.71.2-0.40.4-0.70.7-0.9-0.81.10.81.11.0-1.0-0.90.71.0-0.8-0.8-0.70.8-0.80.80.9-0.9-0.7
Reaction time trials on left0.20.71.2-0.40.4-0.70.7-0.9-0.91.10.91.11.1-1.1-0.90.81.0-0.9-0.8-0.70.8-0.80.80.9-0.9-0.7
Reaction time mean0.61.42.1-0.10.10.8-0.61.11.2-1.3-1.2-1.3-1.31.31.3-1.3-1.41.41.51.2-1.41.4-1.4-1.11.11.2
Reaction time mean AUC0.51.21.9-0.10.10.7-0.51.01.1-1.2-1.1-1.2-1.21.21.2-1.2-1.31.31.41.1-1.31.3-1.3-1.01.01.1
Median of all reaction times1.11.72.5-0.00.00.9-0.71.31.3-1.3-1.3-1.4-1.41.41.4-1.3-1.51.51.61.3-1.51.5-1.5-1.31.31.4
Reaction time omissions0.10.10.60.5-0.50.1-0.80.3-0.10.20.20.30.3-0.3-0.30.40.3-0.2-0.2-0.20.2-0.20.20.3-0.3-0.0
Reaction time false alarm rate0.81.04.32.1-2.11.4-1.81.40.9-0.6-0.8-0.4-0.40.40.6-0.6-0.40.60.50.7-0.50.5-0.5-1.01.01.1
Reaction time premature initiation rate0.10.20.30.4-0.40.4-0.00.10.4-0.5-0.4-0.6-0.60.60.5-0.5-0.50.40.40.4-0.50.5-0.50.1-0.10.1
Reaction time premature initiations0.00.00.20.2-0.20.00.3-0.4-0.00.10.00.00.0-0.0-0.0-0.00.1-0.0-0.00.0-0.00.0-0.00.5-0.5-0.3
Std. dev. reaction times0.10.30.6-0.10.10.4-0.40.40.6-0.6-0.6-0.6-0.70.70.7-0.7-0.80.70.70.6-0.60.6-0.6-0.40.40.6
Reaction time trials completed0.20.71.2-0.40.4-0.70.7-0.9-0.91.10.91.11.1-1.1-0.90.81.0-0.9-0.8-0.70.8-0.80.80.9-0.9-0.7
Reaction time trials AUC0.30.91.5-0.50.5-0.80.9-1.1-1.01.21.01.21.2-1.2-1.00.91.1-0.9-0.9-0.80.9-0.90.91.1-1.1-0.9
Run reversals in cocaine runway, females0.10.10.7-0.80.8-0.30.7-0.30.0-0.2-0.1-0.3-0.30.30.2-0.4-0.30.40.30.5-0.20.2-0.2-0.20.20.1
Run reversals in cocaine runway, males0.20.21.0-1.01.0-0.71.0-0.8-0.40.10.30.00.0-0.0-0.20.10.0-0.2-0.3-0.10.3-0.30.30.4-0.4-0.3
Latency to leave start box in cocaine runway0.60.81.4-1.11.1-1.01.2-0.8-0.90.80.90.70.7-0.7-0.80.90.9-0.9-0.9-0.80.9-0.90.91.0-1.0-0.7
Latency to leave start box in cocaine runway, F0.20.20.5-0.50.5-0.50.4-0.2-0.50.40.50.40.4-0.4-0.50.50.7-0.5-0.5-0.50.5-0.50.50.6-0.6-0.6
Latency to leave start box in cocaine runway, M0.40.31.8-1.01.0-0.81.3-0.9-0.50.40.50.20.2-0.2-0.30.40.2-0.4-0.4-0.40.4-0.40.40.6-0.6-0.1
Std. dev. time between licks in bursts0.30.52.71.1-1.10.9-1.61.20.5-0.3-0.5-0.1-0.10.10.3-0.2-0.10.40.60.2-0.60.6-0.6-0.70.70.7
Total sessions with >9 infusions1.41.74.3-2.12.1-1.71.7-1.6-1.20.91.20.80.8-0.8-1.01.40.7-1.2-1.3-1.11.2-1.21.21.3-1.3-1.3
Short access day 1 total inactive lever presses4.48.810.5-3.23.2-3.02.1-2.5-3.23.13.13.23.2-3.2-3.13.03.0-2.9-2.9-2.82.8-2.82.82.8-2.8-2.9
Short access day 10 total inactive lever presses0.53.64.7-0.90.9-1.71.6-1.8-2.02.11.92.22.2-2.2-2.02.01.9-1.9-1.9-1.82.0-2.02.02.1-2.1-2.1
Short access day 1 total infusions3.05.98.1-2.82.8-2.72.2-2.4-2.42.22.42.12.1-2.1-2.32.72.0-2.5-2.6-2.22.6-2.62.62.5-2.5-2.4
Short access day 10 total infusions2.13.57.9-2.82.8-2.22.2-2.0-1.91.61.81.51.5-1.5-1.61.91.3-1.6-1.7-1.51.7-1.71.71.8-1.8-1.8
Short access total infusions1.62.35.4-2.32.3-1.91.6-1.6-1.41.11.41.11.1-1.1-1.21.70.9-1.4-1.4-1.21.4-1.41.41.6-1.6-1.6
Short access day 1 locomotion2.64.36.4-2.42.4-2.32.3-2.5-2.01.72.01.61.6-1.6-1.92.31.6-2.1-2.1-1.92.1-2.12.12.2-2.2-2.3
Short access day 10 total locomotion0.62.34.0-1.41.4-1.51.9-1.9-1.51.41.51.31.3-1.3-1.41.61.2-1.4-1.3-1.51.3-1.31.31.7-1.7-2.0
Short access total locomotion0.40.62.0-1.41.4-1.01.1-1.0-0.60.30.60.30.3-0.3-0.40.80.1-0.6-0.6-0.50.6-0.60.60.9-0.9-1.0
One hour access (0.3 mA shock)1.82.15.2-2.32.3-1.82.0-1.8-1.41.31.41.21.2-1.2-1.21.41.1-1.3-1.2-1.41.2-1.21.21.2-1.2-1.2
Compulsive drug intake1.31.94.12.0-2.01.6-2.01.81.2-0.9-1.2-0.8-0.80.81.0-1.7-0.91.31.21.4-1.31.3-1.3-1.41.41.4
One hour access (shock baseline)1.54.09.7-3.13.1-2.42.8-2.5-1.91.61.91.51.5-1.5-1.62.11.5-1.8-1.6-1.91.7-1.71.71.7-1.7-1.7
Social response proportion0.20.31.0-0.30.30.20.30.40.4-0.6-0.4-0.6-0.60.60.5-0.4-0.60.40.50.2-0.40.4-0.4-0.90.91.0
Social responses0.10.20.70.7-0.70.5-0.10.40.4-0.3-0.4-0.3-0.30.30.30.0-0.30.20.4-0.1-0.40.4-0.4-0.60.60.8
Social time0.20.30.5-0.10.10.3-0.00.20.5-0.6-0.5-0.7-0.70.70.6-0.5-0.60.50.50.5-0.60.6-0.6-0.50.50.5
Soleus weight4.212.314.5-2.72.7-3.43.2-3.3-3.63.83.63.73.7-3.7-3.63.73.8-3.7-3.6-3.73.5-3.53.53.4-3.4-3.5
Bone: stiffness0.00.00.20.4-0.40.1-0.1-0.2-0.10.20.10.20.2-0.2-0.10.20.2-0.1-0.1-0.2-0.20.2-0.20.1-0.1-0.1
Tibialis anterior weight3.110.613.5-1.71.7-2.92.5-3.0-3.43.73.43.73.6-3.6-3.53.73.6-3.6-3.4-3.73.3-3.33.33.1-3.1-3.3
Time to tail flick, vehicle, before self-admin0.60.81.8-0.00.00.5-0.40.20.9-1.2-0.9-1.4-1.31.31.1-0.9-1.20.90.81.2-0.70.7-0.7-0.70.70.6
Time to tail flick, vehicle, after self-admin2.04.15.81.8-1.82.0-1.61.72.2-2.3-2.2-2.3-2.32.32.2-1.9-2.41.91.82.2-1.71.7-1.7-1.91.91.9
Time to tail flick, test, before self-admin0.10.10.3-0.60.6-0.4-0.1-0.3-0.30.10.30.00.0-0.0-0.20.30.1-0.2-0.2-0.20.3-0.30.30.4-0.4-0.5
Time to tail flick, test, after self-admin0.30.31.1-1.01.0-0.70.9-0.9-0.40.30.40.10.1-0.1-0.30.30.1-0.3-0.4-0.30.3-0.30.30.3-0.3-0.5
Delta time to tail flick, vehicle, before/after SA0.20.21.21.1-1.10.6-0.50.60.4-0.2-0.4-0.2-0.20.20.3-0.2-0.30.10.10.2-0.10.1-0.1-0.30.30.4
Delta time to tail flick, test, before/after SA1.31.62.8-1.51.5-1.41.7-1.4-1.31.41.31.31.3-1.3-1.31.21.3-1.2-1.2-1.31.1-1.11.11.0-1.0-1.2
Tibia length2.57.010.01.7-1.72.4-2.62.72.6-2.7-2.7-2.6-2.62.62.7-2.7-2.62.72.72.7-2.72.7-2.7-3.13.13.2
Ambulatory time before self-admin0.00.10.6-0.70.7-0.30.8-0.3-0.20.20.10.10.1-0.1-0.10.10.20.00.1-0.0-0.10.1-0.1-0.20.2-0.1
Ambulatory time after self-admin0.91.52.70.6-0.61.1-0.81.31.1-1.0-1.2-1.0-1.01.01.2-1.4-0.91.41.41.4-1.41.4-1.4-1.61.61.4
Bone: tissue strength0.80.81.20.5-0.50.8-0.50.70.9-1.0-1.0-1.0-1.01.01.0-1.1-1.01.11.01.1-1.01.0-1.0-0.90.90.9
Total heroin consumption2.52.93.9-1.51.5-1.71.1-1.5-1.81.71.81.81.7-1.7-1.81.82.0-1.8-1.8-1.81.7-1.71.71.6-1.6-1.7
Bone: trabecular number2.54.76.6-1.71.7-2.11.7-1.5-2.32.52.32.62.6-2.6-2.42.32.5-2.3-2.4-2.32.3-2.32.31.4-1.4-1.3
Bone: trabecular spacing2.43.54.91.0-1.01.6-1.31.31.9-2.2-1.9-2.2-2.22.22.1-2.2-2.12.22.22.2-2.22.2-2.2-1.11.11.1
Bone: trabecular thickness0.60.81.3-0.50.5-0.70.5-0.1-0.91.10.91.11.1-1.1-1.01.01.1-1.0-1.1-1.01.1-1.11.10.1-0.1-0.0
Bone: trabecular tissue density0.30.50.9-0.90.9-0.80.7-0.8-0.80.80.70.80.8-0.8-0.70.70.8-0.6-0.4-0.70.5-0.50.50.9-0.9-0.8
Water consumed over 24 hours0.20.41.00.4-0.4-0.1-0.1-0.0-0.50.90.61.01.0-1.0-0.70.90.9-0.7-0.6-0.90.5-0.50.50.3-0.3-0.3
Number of responses in last shaping day0.50.62.9-1.71.7-1.00.5-0.6-0.70.30.70.20.2-0.2-0.51.10.5-0.8-0.7-0.90.6-0.60.60.5-0.5-0.3