Hub : Genes

Abce1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression Abce1 0.13 0.06 3.2e-04 0.02 0.05 0.04 0.01 1.8e-02 1.1e-04 5.2e-04 2.2e-02
2 IC intron excision ratio chr19_45131082_45132488 0.17 0.09 8.6e-04 0.04 0.05 0.08 0.06 1.0e-02 3.1e-03 3.1e-04 1.6e-03
3 IC intron excision ratio chr19_45130856_45130960 0.16 0.09 1.4e-03 0.05 0.04 0.07 0.06 4.5e-03 1.2e-02 4.5e-04 1.2e-03
4 PL gene expression Abce1 0.1 0.07 8.9e-04 0.03 0.03 0.03 0.03 1.3e-04 2.1e-04 5.4e-04 4.9e-04
5 PL mRNA stability Abce1 0.05 0.03 1.6e-03 0.03 0.03 0.03 0.03 2.5e-04 8.7e-04 3.1e-04 4.2e-04
6 BLA gene expression Abce1 0.21 0.09 1.4e-06 0.13 0.11 0.11 0.12 2.6e-07 1.2e-06 2.5e-06 5.5e-07
7 Brain gene expression Abce1 0.03 0.02 6.0e-03 0.03 0.02 0.01 0.01 2.1e-03 9.7e-03 6.7e-02 2.0e-02
8 Brain mRNA stability Abce1 0.12 0.07 7.1e-07 0.08 0.07 0.07 0.08 1.2e-07 9.3e-07 5.0e-07 1.3e-07
9 Adipose gene expression Abce1 0.06 0.03 1.2e-05 0.02 0.04 0.04 0.03 9.7e-04 2.1e-05 8.5e-05 1.6e-04
10 Adipose mRNA stability Abce1 0.13 0.07 9.9e-08 0.06 0.06 0.07 0.07 8.2e-07 8.8e-07 7.1e-08 3.3e-08
11 NAcc gene expression Abce1 0.04 0.02 1.8e-05 0.02 0.02 0.02 0.02 9.8e-04 2.3e-04 7.7e-04 1.6e-03
12 NAcc mRNA stability Abce1 0.06 0.03 1.5e-07 0.05 0.05 0.04 0.04 4.0e-08 1.1e-07 5.9e-07 1.5e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.40.61.9-1.4-1.01.1-0.5-0.41.1-0.1-0.1-0.9-0.5-0.9-0.2
Area under the delay curve0.40.41.1-0.70.0-0.20.50.60.81.01.00.60.50.60.3
BMI with tail1.65.49.91.13.0-3.02.92.1-0.92.42.42.41.63.11.5
BMI without tail0.61.85.0-2.21.3-1.11.91.41.41.31.30.50.90.90.7
Body weight0.41.87.4-2.7-1.41.51.30.92.20.60.60.30.90.40.4
Weight adjusted by age0.40.61.81.4-0.50.40.20.3-0.30.90.90.71.20.70.1
Bone surface0.30.51.5-0.9-1.01.1-0.2-0.31.2-0.1-0.1-0.9-0.5-0.8-0.2
Bone volume0.71.23.9-1.5-1.82.0-0.3-0.41.80.00.0-0.9-0.5-1.0-0.0
Breakpoint value in progressive ratio session2.32.75.00.60.9-1.1-1.4-1.7-1.6-2.1-2.1-1.8-2.2-1.4-2.2
Number of licking bursts0.30.61.6-1.2-0.50.50.60.81.20.50.50.40.60.31.0
Context. condit. distance diff. score0.50.61.60.9-1.31.3-0.9-0.8-0.00.50.50.50.50.20.6
Locomotion velocity, session 10.40.41.51.2-0.30.5-0.9-0.90.2-0.7-0.7-0.4-0.5-0.2-0.3
Locomotion distance, session 10.30.41.51.20.2-0.1-0.4-0.50.2-0.8-0.8-0.6-0.7-0.2-0.8
Locomotion velocity, session 20.10.10.90.1-0.20.40.60.50.90.10.1-0.20.10.1-0.0
Locomotion distance, session 20.20.30.80.4-0.10.2-0.2-0.40.5-0.5-0.5-0.8-0.9-0.5-0.7
Locomotion velocity, session 30.10.20.50.4-0.40.60.40.10.3-0.1-0.10.30.70.10.5
Locomotion distance, session 30.50.62.4-0.50.5-0.11.61.31.20.10.10.10.60.30.5
Stereotopy head waving bouts, day 31.11.32.3-0.20.6-0.51.41.40.41.51.51.21.51.21.3
Stereotopy head waving duration, day 31.41.72.90.80.4-0.31.51.2-0.01.61.61.71.71.51.7
Locomotion velocity, session 70.10.10.2-0.0-0.00.10.10.50.50.10.1-0.10.4-0.0-0.2
Locomotion distance, session 70.20.20.5-0.0-0.20.2-0.7-0.40.5-0.1-0.1-0.7-0.4-0.5-0.6
Stereotopy head waving bouts, day 71.51.75.9-2.02.4-2.41.31.30.4-0.6-0.6-0.50.00.0-0.3
Stereotopy head waving duration, day 70.91.13.5-1.61.9-1.81.41.20.7-0.2-0.2-0.20.30.10.1
Locomotion velocity, session 80.81.02.31.4-0.80.6-1.5-1.5-0.8-0.9-0.9-0.5-0.9-0.6-0.8
Locomotion distance, session 80.30.52.41.5-0.60.7-1.0-1.10.00.30.3-0.1-0.2-0.1-0.0
Degree of sensitization distance0.70.73.20.6-1.00.7-1.8-1.2-0.40.20.2-0.4-0.6-0.7-0.8
Degree of sensitization stereotypy1.11.23.4-1.81.8-1.80.80.80.5-1.0-1.0-0.8-0.4-0.4-0.5
Conditioned locomotion0.40.52.4-0.2-1.61.4-0.7-0.70.3-0.1-0.1-0.0-0.1-0.60.3
Cocaine response after cond. corrected1.31.65.11.3-2.22.3-1.7-1.50.60.70.7-0.1-0.0-0.50.2
Cocaine response after cond. not corrected1.21.44.61.5-2.02.1-1.6-1.60.60.10.1-0.1-0.1-0.40.3
Cocaine response before conditioning0.50.61.6-0.21.3-1.20.80.5-0.3-1.3-1.3-0.2-0.30.2-0.2
Saline control response1.01.35.0-0.1-1.51.9-0.8-0.92.2-0.8-0.8-1.0-0.3-1.1-0.0
Bone: connectivity density0.10.10.3-0.50.2-0.10.20.30.50.20.2-0.5-0.2-0.4-0.0
Bone: cortical apparent density0.30.40.8-0.00.9-0.90.70.9-0.30.70.70.40.30.60.1
Bone: cortical area0.91.34.50.4-2.12.1-1.4-1.40.1-0.6-0.6-0.6-0.9-1.0-0.5
Bone: cortical porosity0.60.72.00.3-0.80.9-0.3-0.90.1-1.4-1.4-0.6-0.6-0.7-0.3
Bone: cortical porosity1.11.23.0-0.4-1.21.2-0.5-1.10.2-1.7-1.7-0.9-0.8-1.2-0.6
Bone: cortical thickness0.20.31.80.6-0.50.3-0.4-0.4-1.3-0.6-0.60.1-0.6-0.0-0.4
Bone: cortical thickness0.10.10.30.30.5-0.4-0.10.4-0.5-0.2-0.20.0-0.40.3-0.3
Bone: cortical tissue density0.20.30.8-0.20.8-0.80.70.9-0.10.70.70.30.30.50.1
Condit. Reinf. active minus inactive responses0.80.92.3-1.30.1-0.3-0.5-0.6-0.5-1.5-1.5-1.0-0.8-1.0-1.0
Condit. Reinf. active-inactive response ratio0.70.81.5-0.2-0.20.0-1.1-1.2-0.6-1.1-1.1-1.0-0.9-1.0-1.0
Condit. Reinf. active responses0.70.93.9-2.00.0-0.10.0-0.10.4-1.3-1.3-1.0-0.6-0.9-0.8
Condit. Reinf. inactive responses0.60.84.5-2.1-0.10.10.30.41.0-0.8-0.8-1.0-0.6-0.8-0.6
Incentive salience index mean1.11.43.5-1.90.5-0.6-0.4-0.50.1-1.6-1.6-1.5-1.2-1.3-1.3
Condit. Reinf. lever presses0.91.36.0-2.51.4-1.30.30.20.7-0.8-0.8-1.3-0.9-0.8-0.9
Condit. Reinf. active minus inactive responses0.60.82.50.5-1.61.6-1.1-0.80.2-0.7-0.70.40.2-0.10.8
Condit. Reinf. active-inactive response ratio1.11.24.90.6-2.22.1-1.5-1.30.40.10.10.40.2-0.20.8
Condit. Reinf. active responses0.30.41.4-0.2-0.90.8-0.7-0.40.1-1.2-1.20.1-0.1-0.20.4
Condit. Reinf. inactive responses0.30.42.1-0.30.1-0.2-0.2-0.0-0.3-1.4-1.4-0.4-0.5-0.4-0.5
Condit. Reinf. lever presses0.60.81.80.31.2-1.31.31.2-0.8-0.4-0.40.80.11.10.5
Condit. Reinf. lever reinforcers received0.20.31.2-0.1-0.60.5-0.3-0.0-0.1-1.1-1.10.40.00.20.5
Conditioned reinforcement - actives0.50.82.0-0.8-0.50.61.41.41.30.70.70.70.70.70.6
Conditioned reinforcement - inactives0.71.02.70.00.8-0.51.61.71.21.21.20.60.61.00.6
Conditioned locomotion0.20.31.3-1.1-0.00.10.40.51.0-0.5-0.5-0.4-0.3-0.4-0.5
Patch foraging indifference point 0 sec0.40.75.9-2.40.2-0.20.81.20.8-0.0-0.0-0.2-0.00.10.1
Patch foraging indifference point AUC0.20.20.80.90.6-0.40.30.40.6-0.3-0.3-0.4-0.2-0.1-0.5
Delay disc. indifference point, 0s delay0.40.43.11.81.0-0.70.1-0.00.60.30.3-0.1-0.20.4-0.2
Delay disc. indifference point, 16s delay0.10.11.10.0-0.1-0.3-0.20.1-1.00.30.30.50.00.3-0.1
Delay disc. indifference point, 2s delay0.70.81.90.40.9-0.91.41.31.01.01.00.50.70.9-0.2
Delay disc. indifference point, 24s delay0.30.31.0-1.0-0.70.5-0.5-0.40.20.60.60.50.30.10.6
Delay disc. indifference point, 4s delay0.90.93.2-0.5-0.80.80.50.41.81.31.30.60.90.60.7
Delay disc. indifference point, 8s delay0.50.51.2-0.90.1-0.20.40.41.01.11.10.70.70.70.6
Indifference point function ln k0.40.71.4-1.2-0.50.50.70.3-0.21.11.10.90.80.81.1
Indifference point function log k0.40.71.4-1.2-0.50.50.70.3-0.21.11.10.90.80.81.1
Patch foraging total patch changes 0 sec0.40.86.4-2.50.00.00.81.30.8-0.1-0.1-0.10.10.00.3
Patch foraging total patch changes 12 sec0.60.81.7-1.01.3-1.10.41.10.8-0.7-0.7-1.0-0.4-0.5-1.1
Patch foraging total patch changes 18 sec0.50.73.2-0.90.4-0.00.20.61.8-1.1-1.1-1.1-0.2-0.9-0.3
Patch foraging total patch changes 24 sec0.40.73.1-1.80.2-0.10.30.71.0-0.9-0.9-0.9-0.3-0.8-0.6
Patch foraging total patch changes 6 sec0.20.32.0-1.40.5-0.50.40.90.70.30.3-0.3-0.10.1-0.1
Patch foraging time to switch 0 sec0.20.51.00.70.4-0.4-0.8-0.8-0.2-1.0-1.0-0.7-0.3-0.6-1.0
Patch foraging water rate 0 sec0.20.41.0-1.0-1.00.9-0.3-0.10.1-0.3-0.3-0.4-0.8-0.6-0.4
Patch foraging water rate 12 sec0.81.73.0-0.30.4-0.41.51.4-0.21.71.71.71.71.51.5
Patch foraging water rate 18 sec0.81.35.5-2.4-0.1-0.11.01.0-0.11.51.50.91.10.51.1
Patch foraging water rate 24 sec0.81.13.10.30.2-0.40.91.0-1.11.81.81.10.90.81.2
Patch foraging water rate 6 sec0.81.22.2-1.10.4-0.5-1.1-1.0-0.9-0.9-0.9-1.4-1.5-1.4-1.3
Seeking ratio, delayed vs. immediate footshock0.40.51.20.10.0-0.00.60.60.11.11.10.90.70.81.0
Distance traveled before self-admin0.60.82.31.51.3-1.00.91.00.20.50.50.70.71.00.4
Distance traveled after self-admin0.10.10.3-0.3-0.10.20.40.40.60.20.2-0.10.20.0-0.4
Extensor digitorum longus weight0.72.69.20.52.8-3.00.80.4-1.7-1.0-1.0-1.1-1.7-0.1-1.9
Bone: elastic displacement0.20.21.1-0.10.2-0.31.00.60.1-0.2-0.20.20.60.10.0
Bone: elastic work0.10.10.5-0.4-0.30.00.2-0.0-0.7-0.4-0.40.1-0.0-0.1-0.3
Bone: endosteal estimation0.61.42.4-0.2-1.11.3-1.2-1.21.5-0.8-0.8-1.6-1.2-1.3-1.2
Bone: endosteal perimeter2.14.415.10.5-3.63.9-2.7-2.61.8-0.5-0.5-1.3-1.0-1.8-0.3
Epididymis fat weight0.93.012.5-3.5-1.71.91.11.73.30.60.6-0.40.9-0.30.1
Delta time in closed arm before/after self-admin0.30.30.8-0.90.4-0.4-0.2-0.30.6-0.3-0.3-0.7-0.5-0.7-0.2
Delta time in open arm before/after self-admin0.60.61.5-0.1-1.21.0-0.8-0.7-1.2-0.7-0.7-0.1-0.5-0.4-0.6
Diff in mean of infusions in LGA sessions0.81.03.92.00.1-0.2-1.0-1.3-1.0-0.5-0.5-0.7-1.1-0.4-1.3
Delay discount exponential model param0.50.61.50.80.2-0.0-0.6-0.6-1.0-1.2-1.2-0.7-0.7-0.7-0.4
Extinction: sum of active levers before priming3.74.111.6-0.33.4-3.22.92.7-0.11.11.11.21.52.20.5
Active lever presses in extinction session 64.24.28.61.61.8-1.72.32.3-0.32.42.42.41.92.91.3
Bone: final force0.50.81.7-0.2-0.60.5-0.9-0.9-0.4-1.2-1.2-0.9-1.3-0.9-1.2
Bone: final moment0.50.81.5-0.3-0.60.5-0.8-0.8-0.3-1.2-1.2-0.9-1.2-0.9-1.2
Food consumed during 24 hour testing period2.02.86.8-0.70.3-0.2-1.3-1.10.9-1.8-1.8-2.6-2.5-2.0-2.2
Glucose1.52.46.00.5-0.40.2-2.0-2.5-0.8-1.4-1.4-1.7-2.0-1.7-2.0
Heart weight1.01.63.5-0.91.1-0.81.91.01.01.01.01.41.61.71.3
Delay discount hyperbolic model param0.40.51.20.80.00.1-0.6-0.7-1.0-1.1-1.1-0.5-0.6-0.6-0.1
Intermittent access intake day 1-15 change0.40.84.6-2.10.4-0.60.91.01.00.60.6-0.20.40.0-1.0
Intermittent access intake escalation0.30.62.6-1.60.8-0.90.70.80.50.20.2-0.20.2-0.0-1.2
Intermittent access intake escalation 20.20.20.8-0.90.5-0.50.20.40.40.30.3-0.3-0.0-0.1-0.7
Intermitt. access day 1 inactive lever presses0.51.94.4-0.3-1.01.21.31.02.12.02.00.91.20.91.3
Intermitt. access day 15 inactive lever presses0.20.31.21.10.00.00.50.50.20.70.70.60.60.70.4
Intermitt. access escalation Index0.50.72.2-1.0-0.40.70.70.61.50.70.70.41.20.41.1
Intermittent access day 1 total infusions0.61.02.90.7-0.10.21.71.70.70.80.81.20.91.10.9
Intermittent access day 15 total infusions1.42.16.4-0.71.0-0.92.52.51.41.21.21.21.31.40.4
Intermittent access terminal intake (last 3 days)1.41.95.5-0.80.2-0.02.22.31.61.31.31.21.41.20.8
Intermittent access total infusions1.11.33.6-0.3-0.20.31.91.91.30.90.91.21.21.10.9
Intermittent access day 1 locomotion0.70.92.10.60.5-0.41.31.50.71.01.01.00.61.10.9
Intermittent access day 15 total locomotion0.61.14.2-1.10.5-0.21.81.62.00.60.60.50.50.80.3
Intermittent access total locomotion0.40.41.50.60.4-0.21.21.10.60.40.40.70.30.90.3
Intermittent access standard deviation0.91.93.8-1.6-0.10.32.01.81.81.71.70.71.50.70.6
Left kidney weight0.10.61.9-1.40.20.10.61.31.4-0.8-0.8-0.40.2-0.2-0.2
Right kidney weight0.52.25.1-2.2-0.20.4-0.50.20.9-2.3-2.3-1.7-1.2-1.5-1.8
Cocaine induced anxiety0.20.21.21.1-0.20.1-0.5-0.6-0.40.60.6-0.0-0.1-0.1-0.6
Post-drug Anxiety0.40.41.30.1-0.2-0.0-0.9-0.9-0.40.00.0-0.7-0.6-0.7-1.2
Baseline Anxiety0.40.43.4-1.90.1-0.10.60.51.10.20.2-0.20.20.0-0.1
Tail length1.76.827.9-5.3-3.73.8-0.30.14.1-0.6-0.6-1.7-0.0-2.1-0.4
Length with tail1.77.321.7-4.6-4.54.7-0.4-0.24.2-0.8-0.8-1.30.2-1.9-0.3
Length without tail0.41.25.8-0.6-2.32.40.10.31.4-0.2-0.20.00.5-0.1-0.2
Times rat made contact with spout0.70.84.21.02.0-1.60.80.70.50.30.30.0-0.00.60.2
Lifetime Intake1.41.74.2-0.3-0.30.52.11.91.71.01.01.41.41.21.4
Liver weight, left0.40.73.2-1.1-0.80.90.3-0.01.8-0.2-0.2-1.0-0.5-0.7-1.0
Liver weight, right0.30.51.4-0.9-0.91.0-0.40.91.2-0.2-0.2-0.20.5-0.40.2
Locomotor activity0.60.92.11.41.0-0.91.21.5-0.30.90.90.70.41.30.0
Locomotor testing distance0.40.71.61.11.3-1.01.11.20.30.60.60.40.21.10.1
Locomotor testing rearing0.51.13.82.01.7-1.5-0.30.2-0.7-0.7-0.7-0.5-1.00.3-1.2
Locomotion in novel chamber0.50.72.21.3-0.1-0.1-1.0-1.1-1.5-0.4-0.4-0.3-1.0-0.1-0.8
Locomotion in novel chamber post-restriction0.50.96.52.50.10.2-0.5-0.7-0.70.80.80.4-0.10.31.2
Fecal boli incidents, locomotor time 10.20.30.8-0.50.8-0.40.70.90.5-0.6-0.6-0.40.2-0.1-0.7
Change in fecal boli incidents, locomotor task0.40.40.80.1-0.90.8-0.6-0.60.60.60.60.20.2-0.10.9
Time >=10cm from walls, locomotor time 10.70.75.3-2.30.00.20.40.41.2-0.4-0.4-0.70.0-0.70.1
Bouts of movement, locomotor time 11.11.23.51.40.9-1.00.10.3-1.90.60.61.70.91.21.1
Total resting periods, locomotor time 11.01.13.80.50.9-1.10.40.6-1.90.70.71.70.91.21.0
Rest time, locomotor task time 10.70.94.6-2.1-0.30.41.21.30.70.40.40.50.90.30.7
Distance moved, locomotor task time 11.11.63.91.0-0.1-0.0-1.6-2.0-0.3-1.3-1.3-1.4-1.8-1.1-1.3
Vertical activity count, locomotor time 11.74.28.00.6-0.90.9-2.8-2.80.4-2.1-2.1-2.6-2.3-2.7-2.2
Time >=10cm from walls, locomotor time 20.71.12.2-0.1-1.20.9-1.5-1.4-1.1-1.2-1.2-0.6-0.8-1.1-0.6
Bouts of movement, locomotor time 21.01.63.3-1.20.8-1.01.71.3-0.51.11.11.81.11.81.0
Total resting periods, locomotor time 20.91.63.3-1.60.8-1.01.81.4-0.31.11.11.71.11.60.8
Rest time, locomotor task time 20.40.52.4-1.5-0.00.10.70.90.80.60.60.30.90.40.3
Distance moved, locomotor task time 21.01.13.81.3-0.40.1-1.3-1.9-1.3-0.8-0.8-0.6-1.4-0.7-0.5
Vertical activity count, locomotor time 23.95.412.11.3-1.51.5-3.4-3.5-0.5-2.5-2.5-2.4-2.4-2.8-1.7
Light reinforcement 12.76.714.6-1.01.6-1.4-1.7-1.50.3-3.3-3.3-3.8-3.4-3.0-3.6
Light reinforcement 24.26.513.5-2.30.4-0.3-2.0-1.7-0.2-3.7-3.7-3.4-3.2-3.2-2.5
Bone: marrow area0.61.32.3-0.2-1.11.2-1.2-1.21.4-0.8-0.8-1.5-1.2-1.3-1.2
Bone: maximum diameter1.01.87.20.5-2.62.7-1.6-1.51.00.40.4-0.4-0.5-0.90.3
Bone: maximum force0.50.82.0-0.2-1.41.2-1.0-0.9-0.1-0.7-0.7-0.7-1.2-0.8-0.9
Bone: maximum moment0.50.82.0-0.3-1.41.3-0.9-0.90.1-0.8-0.8-0.8-1.1-0.8-0.8
Mean time between licks in bursts0.20.52.0-1.4-0.30.2-0.2-0.50.4-0.6-0.6-0.9-0.6-0.7-0.7
Mean num. licks in bursts0.50.83.11.71.8-1.50.2-0.1-0.60.10.1-0.2-0.40.3-0.6
Cd content in liver0.20.20.80.0-0.30.5-0.5-0.20.1-0.9-0.90.30.20.10.5
Co content in liver1.21.45.8-2.41.5-1.70.20.2-0.5-1.1-1.1-1.0-1.0-0.6-1.0
Cu content in liver0.50.62.10.30.7-0.8-0.4-0.8-1.4-1.0-1.0-0.4-0.8-0.4-0.6
Fe content in liver0.40.51.2-1.0-0.30.10.50.3-0.31.11.10.60.70.20.6
K content in liver0.90.92.01.0-1.21.40.50.31.11.01.00.81.00.70.7
Mg content in liver0.80.82.50.5-1.61.6-0.9-0.80.50.90.90.40.60.10.6
Mn content in liver0.70.83.40.2-1.81.8-0.6-0.91.20.40.4-0.20.1-0.50.1
Na content in liver0.20.31.00.4-0.81.00.40.01.0-0.0-0.00.10.20.20.5
Rb content in liver0.20.20.90.40.5-0.6-0.3-0.1-0.9-0.3-0.3-0.1-0.3-0.1-0.5
Se content in liver1.51.85.50.5-1.40.9-2.3-2.1-2.1-0.4-0.4-0.6-1.0-1.2-1.1
Sr content in liver0.60.51.40.1-0.60.61.20.80.60.40.40.70.90.70.9
Zn content in liver0.40.51.2-0.5-0.30.2-1.1-1.00.2-0.7-0.7-0.8-0.6-0.8-0.7
Bone: minimum diameter1.42.55.6-0.7-2.42.4-1.9-1.81.2-0.7-0.7-1.7-1.4-1.8-1.2
Time in familiar zone, hab. session 12.22.14.5-0.51.9-2.1-0.6-0.7-1.1-1.1-1.1-1.7-1.8-1.1-2.1
Time in novel zone, hab. session 13.93.97.20.8-0.60.82.32.21.02.12.12.52.52.32.7
Total zone transitions, hab. session 10.20.30.70.60.8-0.60.50.20.3-0.0-0.0-0.5-0.50.2-0.8
Total locomotion distance, hab. session 10.20.31.20.10.3-0.3-0.1-0.50.3-0.2-0.2-0.8-0.7-0.4-1.1
Locomotion velocity, hab. session 10.50.71.7-0.30.1-0.1-0.7-1.10.5-0.7-0.7-1.2-1.0-0.9-1.3
Time in familiar zone, hab. session 21.11.12.3-1.00.3-0.5-0.7-1.0-0.3-1.2-1.2-1.4-1.5-1.3-1.2
Time in novel zone, hab. session 20.30.30.80.5-0.30.30.30.4-0.50.60.60.90.90.80.5
Total zone transitions, hab. session 20.20.20.50.60.5-0.1-0.1-0.30.7-0.7-0.7-0.4-0.40.0-0.3
Total locomotion distance, hab. session 21.52.04.50.4-0.40.4-2.0-2.1-0.2-1.7-1.7-1.5-1.5-1.5-1.6
Locomotion velocity, hab. session 21.41.83.90.4-0.20.2-1.9-2.0-0.2-1.6-1.6-1.5-1.5-1.4-1.6
Novel to familiar place preference ratio0.50.51.61.30.5-0.50.20.3-0.11.01.00.60.70.80.4
Novelty place preference0.20.21.01.00.6-0.60.10.1-0.20.50.50.20.30.5-0.1
Time in novel zone, NPP test0.30.30.60.70.7-0.70.40.3-0.00.70.70.30.50.60.1
Total zone transitions, NPP test0.50.71.9-0.2-0.10.5-0.4-0.61.4-1.0-1.0-1.3-0.9-0.8-0.8
Total locomotion distance, NPP test0.30.42.6-0.1-0.71.10.0-0.31.60.10.1-0.10.4-0.10.4
Locomotion velocity, NPP test0.40.62.3-0.0-1.21.5-0.5-0.71.5-0.2-0.2-0.40.0-0.50.0
Intraocular pressure1.01.45.10.31.2-1.11.72.30.11.01.00.91.01.30.4
Delta distance traveled before/after self-admin0.20.20.8-0.1-0.90.7-0.3-0.50.30.00.0-0.4-0.4-0.4-0.6
Delta ambulatory time before/after self-admin0.70.81.8-1.2-0.80.6-0.6-0.80.9-0.5-0.5-1.3-1.0-1.1-1.2
Parametrial fat weight0.40.93.4-0.9-1.61.8-0.7-0.81.40.20.2-0.3-0.1-0.50.5
Pavlov. Cond. lever latency0.20.31.21.10.1-0.10.0-0.0-0.20.30.30.60.60.40.9
Pavlov. Cond. magazine entry latency0.40.51.60.41.1-1.30.80.6-0.9-0.5-0.5-0.0-0.50.4-0.4
Pavlov. Cond. change in total contacts0.60.61.2-0.70.3-0.5-0.6-0.7-0.3-0.9-0.9-0.9-1.0-0.7-1.1
Pavlov. Cond. index score0.10.10.3-0.10.3-0.30.60.4-0.2-0.3-0.3-0.0-0.20.3-0.4
Pavlov. Cond. latency score0.10.10.4-0.20.2-0.30.30.2-0.2-0.4-0.4-0.2-0.50.1-0.6
Pavlov. Cond. lever contacts0.10.10.4-0.60.1-0.10.30.3-0.2-0.2-0.2-0.2-0.30.0-0.5
Pavlov. Cond. magazine entry number0.20.30.5-0.3-0.70.7-0.7-0.50.70.70.70.00.4-0.30.3
Pavlov. Cond. intertrial magazine entries1.31.63.1-1.4-1.81.4-1.5-1.50.1-1.2-1.2-0.9-0.7-1.6-1.0
Pavlov. Cond. lever-magazine prob. diff.0.00.10.20.20.0-0.10.20.0-0.4-0.3-0.30.1-0.30.3-0.3
Pavlov. Cond. response bias0.30.41.0-0.61.0-1.00.70.5-0.3-0.7-0.7-0.3-0.40.1-0.6
Pavlov. Cond. lever latency1.31.74.31.0-2.12.1-1.3-1.20.51.81.80.50.8-0.20.6
Pavlov. Cond. magazine entry latency2.22.76.8-1.41.3-1.3-0.00.1-0.3-2.6-2.6-1.9-2.0-1.3-1.9
Pavlov. Cond. change in total contacts0.81.34.8-0.22.2-2.11.41.5-0.6-0.8-0.80.30.00.80.2
Pavlov. Cond. index score1.72.35.3-1.12.3-2.30.90.9-0.6-2.2-2.2-1.0-1.3-0.3-1.1
Pavlov. Cond. latency score1.72.35.2-1.12.2-2.10.91.0-0.5-2.3-2.3-1.1-1.4-0.3-1.2
Pavlov. Cond. lever contacts1.41.95.3-1.12.3-2.31.21.2-0.6-1.7-1.7-0.5-0.80.1-0.7
Pavlov. Cond. magazine entry number2.12.66.01.3-1.81.8-0.2-0.30.62.42.41.71.91.01.8
Pavlov. Cond. intertrial magazine entries0.10.10.50.3-0.60.7-0.2-0.00.40.00.00.20.40.00.3
Pavlov. Cond. lever-magazine prob. diff.1.72.35.2-1.22.2-2.20.80.8-0.5-2.3-2.3-1.1-1.3-0.4-1.2
Pavlov. Cond. response bias1.41.94.3-1.41.7-1.80.80.8-0.8-2.1-2.1-0.9-1.2-0.3-1.0
Time in closed arm before self-admin0.91.22.70.30.9-0.51.51.61.61.31.30.50.80.80.6
Time in closed arm after self-admin0.40.41.3-0.31.1-0.90.20.21.10.40.4-0.7-0.5-0.5-0.1
Time in open arm before self-admin0.30.30.60.0-0.1-0.0-0.8-0.8-0.6-0.7-0.7-0.4-0.5-0.3-0.6
Time in open arm after self-admin0.40.52.90.6-0.90.6-0.2-0.1-1.7-0.3-0.30.70.20.7-0.3
Bone: periosteal estimation0.92.04.2-0.2-2.02.1-1.6-1.61.3-0.8-0.8-1.5-1.4-1.5-1.1
Bone: periosteal perimeter1.52.59.20.6-2.93.0-2.0-2.01.3-0.2-0.2-0.7-0.7-1.20.1
Bone: post-yield work0.40.61.0-0.7-0.90.8-0.9-0.80.6-0.0-0.0-1.0-1.0-1.0-0.5
Progressive ratio test 1 active lever presses1.01.21.80.6-0.70.81.21.31.01.21.21.30.91.21.3
Progressive ratio test 1 breakpoint1.01.21.90.6-0.70.81.11.30.91.21.21.30.91.21.4
Progressive ratio test 1 inactive lever presses0.91.34.6-0.1-2.12.10.00.11.31.31.30.60.70.20.9
Progressive ratio test 2 active lever presses1.01.21.81.00.30.01.31.31.21.11.11.11.01.21.4
Progressive ratio test 2 breakpoint1.01.11.81.00.30.01.31.31.21.01.01.11.01.21.3
Progressive ratio test 2 inactive lever presses0.10.20.50.60.3-0.10.70.70.60.50.50.20.10.30.2
Incentive Sensitization - Responses0.40.64.12.01.2-0.90.30.10.00.20.20.30.30.50.4
Incentive Sensitization - Breakpoint0.40.53.51.91.1-0.80.2-0.00.10.10.10.20.20.40.3
Sum of active levers in priming session hrs 5-63.73.49.70.52.9-3.1-0.3-0.2-1.9-1.6-1.6-1.5-1.9-0.6-2.8
Progressive ratio0.40.71.91.21.4-1.30.00.1-1.0-0.8-0.8-0.5-0.5-0.2-0.9
Food seeking constrained by brief footshock1.21.54.4-1.1-1.31.30.91.02.11.21.20.91.40.81.0
Seeking ratio, punishment vs. effort0.91.33.6-1.9-1.91.7-0.1-0.21.60.70.70.50.60.11.0
Retroperitoneal fat weight0.83.48.0-2.0-2.62.8-2.0-2.32.0-0.7-0.7-1.6-0.9-2.0-0.6
Reaction time number correct0.30.51.7-0.3-0.00.30.50.60.10.10.11.11.30.71.3
Reaction time mean minus median0.20.61.20.9-1.10.8-0.1-0.4-0.60.60.61.11.10.51.0
Reaction time mean minus median AUC0.30.82.51.6-0.80.6-0.0-0.1-1.00.60.61.31.30.81.0
Reaction time num false alarms0.30.41.20.50.2-0.50.30.8-1.10.50.50.80.50.50.5
Reaction time num false alarms AUC0.61.02.50.30.5-0.71.01.6-0.81.01.01.21.11.11.0
Reaction time trials correct on left0.30.51.7-0.3-0.00.30.50.60.10.10.11.11.30.71.3
Reaction time trials on left0.20.41.5-0.1-0.00.30.40.4-0.10.10.11.11.20.61.2
Reaction time mean0.40.71.71.3-0.60.4-0.30.1-0.70.70.71.31.21.01.0
Reaction time mean AUC0.40.61.51.2-0.60.4-0.20.1-0.70.60.61.21.00.90.9
Median of all reaction times0.40.51.31.0-0.30.1-0.10.4-0.50.60.61.11.01.00.8
Reaction time omissions1.31.98.02.80.2-0.4-1.5-1.8-2.4-0.7-0.7-0.1-0.9-0.4-1.1
Reaction time false alarm rate0.40.51.40.20.4-0.80.81.2-0.80.90.90.60.40.70.3
Reaction time premature initiation rate0.60.81.6-0.11.1-1.2-0.3-0.2-0.5-1.1-1.1-1.0-1.0-0.7-1.3
Reaction time premature initiations0.20.31.0-0.01.0-0.9-0.1-0.1-0.4-0.9-0.9-0.3-0.2-0.3-0.3
Std. dev. reaction times0.50.91.81.1-1.31.0-0.2-0.1-0.51.01.01.21.40.70.9
Reaction time trials completed0.20.41.5-0.1-0.00.30.40.4-0.10.10.11.11.20.61.2
Reaction time trials AUC0.20.41.4-0.2-0.10.40.40.4-0.10.10.11.11.20.61.2
Run reversals in cocaine runway, females2.02.06.1-0.5-2.52.3-1.9-1.5-0.5-1.3-1.3-0.6-0.5-1.60.2
Run reversals in cocaine runway, males2.12.24.2-1.30.4-0.41.92.00.41.81.81.51.51.51.7
Latency to leave start box in cocaine runway0.30.43.11.8-0.00.0-0.6-0.4-0.5-0.2-0.20.2-0.10.3-0.4
Latency to leave start box in cocaine runway, F1.01.210.63.30.5-0.5-0.2-0.1-0.60.60.60.80.51.0-0.2
Latency to leave start box in cocaine runway, M0.70.71.6-1.0-0.40.4-0.8-0.6-0.1-1.3-1.3-0.8-0.8-0.9-0.6
Std. dev. time between licks in bursts0.20.32.1-1.4-0.70.6-0.3-0.10.70.20.2-0.3-0.2-0.30.1
Total sessions with >9 infusions2.53.05.30.80.20.12.02.01.71.81.82.12.02.12.3
Short access day 1 total inactive lever presses0.40.52.2-0.8-1.11.10.3-0.11.50.00.0-0.4-0.6-0.3-0.2
Short access day 10 total inactive lever presses0.41.04.20.80.40.01.01.22.11.21.20.21.00.80.3
Short access day 1 total infusions3.74.910.90.0-1.72.22.02.02.91.91.92.32.81.83.3
Short access day 10 total infusions0.81.12.01.1-0.40.61.41.41.00.90.91.20.91.01.1
Short access total infusions1.82.34.60.6-0.60.91.91.81.81.31.31.71.71.52.1
Short access day 1 locomotion1.41.85.50.2-0.81.21.21.32.31.21.21.31.81.21.3
Short access day 10 total locomotion0.40.82.71.60.7-0.50.60.60.60.80.81.00.51.20.9
Short access total locomotion1.11.42.40.7-0.20.41.31.21.51.41.41.31.41.31.1
One hour access (0.3 mA shock)0.91.03.4-1.21.0-0.91.81.71.20.50.50.40.60.70.0
Compulsive drug intake0.30.42.7-1.6-0.40.4-0.2-0.31.0-0.1-0.1-0.40.2-0.50.5
One hour access (shock baseline)0.50.71.90.11.2-1.41.31.2-0.60.00.00.70.40.8-0.7
Social response proportion0.50.51.00.80.2-0.2-0.9-1.0-0.2-0.7-0.7-1.0-0.8-0.9-0.6
Social responses0.91.15.30.62.3-2.00.70.90.90.10.1-0.8-0.20.2-0.8
Social time0.30.41.90.30.3-0.2-0.30.30.6-0.3-0.3-1.0-0.5-0.5-1.4
Soleus weight0.30.93.6-1.1-0.60.81.30.91.90.80.80.10.70.20.7
Bone: stiffness1.52.45.60.7-1.41.2-2.4-1.9-1.2-1.4-1.4-1.2-2.2-1.2-1.6
Tibialis anterior weight0.20.82.7-0.31.7-1.61.51.20.50.30.30.00.10.70.1
Time to tail flick, vehicle, before self-admin1.41.53.7-0.5-1.31.41.00.91.91.01.01.11.60.91.2
Time to tail flick, vehicle, after self-admin0.30.40.80.6-0.30.4-0.6-0.5-0.0-0.9-0.9-0.8-0.4-0.9-0.8
Time to tail flick, test, before self-admin1.41.53.20.3-0.0-0.2-1.5-1.8-0.6-1.1-1.1-1.4-1.3-1.6-1.6
Time to tail flick, test, after self-admin0.80.81.6-1.2-0.40.1-0.6-0.9-0.3-1.0-1.0-1.3-1.1-1.2-1.0
Delta time to tail flick, vehicle, before/after SA1.61.62.40.80.1-0.2-1.5-1.3-1.4-1.3-1.3-1.4-1.5-1.5-1.4
Delta time to tail flick, test, before/after SA0.30.31.1-1.1-0.30.20.81.00.00.20.20.20.40.40.3
Tibia length0.30.81.5-0.6-0.50.4-1.2-1.1-0.2-1.2-1.2-0.8-1.0-0.7-0.8
Ambulatory time before self-admin1.01.54.92.21.1-0.81.11.2-0.11.01.01.31.11.60.7
Ambulatory time after self-admin0.10.10.70.20.1-0.20.1-0.10.20.00.0-0.6-0.5-0.2-0.9
Bone: tissue strength0.20.20.5-0.5-0.2-0.0-0.2-0.4-0.6-0.7-0.7-0.3-0.5-0.4-0.3
Total heroin consumption0.30.42.21.50.8-0.60.1-0.3-0.5-0.5-0.5-0.3-0.50.3-0.5
Bone: trabecular number0.20.31.1-1.0-0.40.40.60.70.70.80.8-0.00.10.00.2
Bone: trabecular spacing0.20.20.50.6-0.50.7-0.1-0.20.5-0.2-0.20.50.50.40.6
Bone: trabecular thickness0.50.71.4-1.1-1.21.0-1.2-1.10.00.30.3-0.5-0.5-0.9-0.2
Bone: trabecular tissue density0.30.52.10.5-0.90.6-0.9-0.8-1.4-0.3-0.30.3-0.40.2-0.3
Water consumed over 24 hours0.60.83.50.61.9-1.50.40.70.5-0.4-0.4-0.8-0.9-0.2-0.5
Number of responses in last shaping day2.52.84.91.20.4-0.42.12.00.52.22.22.01.92.10.9