Hub : Genes

Atg16l2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000019413 0.05 0.03 7.5e-06 0.04 0.04 0.04 0.03 2.0e-05 5.1e-05 3.9e-05 1.3e-04
2 BLA gene expression ENSRNOG00000019413 0.36 0.14 3.6e-11 0.2 0.18 0.17 0.18 6.0e-11 5.2e-10 1.8e-09 4.4e-10
3 BLA mRNA stability ENSRNOG00000019413 0.08 0.06 8.0e-03 0.03 0.02 0.01 0.03 6.2e-03 2.1e-02 5.4e-02 1.1e-02
4 Brain gene expression ENSRNOG00000019413 0.05 0.03 1.8e-04 0.02 0.04 0.04 0.03 6.5e-03 1.6e-04 1.5e-04 6.1e-04
5 Eye intron excision ratio chr1:155698192:155698296 0.47 0.24 3.9e-03 0.03 0.06 0.04 0.01 1.2e-01 4.3e-02 8.8e-02 2.3e-01
6 Liver gene expression ENSRNOG00000019413 0.02 0.02 9.8e-03 0 0.01 -0 0 1.2e-01 5.5e-02 5.0e-01 1.0e-01
7 Liver intron excision ratio chr1:155701366:155703063 0.29 0.14 2.2e-14 0.07 0.1 0.09 0.1 3.8e-08 7.8e-11 4.6e-10 1.1e-10
8 Liver intron excision ratio chr1:155708732:155710770 0.47 0.19 0.0e+00 0.09 0.14 0.16 0.13 3.4e-10 8.2e-15 2.8e-17 2.3e-14
9 Liver mRNA stability ENSRNOG00000019413 0.04 0.03 2.3e-03 0 0 0 0 1.7e-01 8.8e-02 1.5e-01 2.4e-01
10 NAcc gene expression ENSRNOG00000019413 0.08 0.05 3.4e-04 0.06 0.04 0.05 0.05 6.2e-05 1.2e-03 9.0e-05 1.6e-04
11 OFC gene expression ENSRNOG00000019413 0.26 0.13 6.6e-04 0.08 0.09 0.07 0.09 6.4e-03 3.5e-03 7.9e-03 4.1e-03
12 PL gene expression ENSRNOG00000019413 0.21 0.09 8.4e-12 0.16 0.15 0.13 0.16 2.7e-12 2.6e-11 3.3e-10 6.5e-12

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
BMI with tail0.30.92.6-1.60.3-0.31.41.30.7-0.40.80.90.60.90.8
BMI without tail1.12.26.1-1.1-1.4-2.5-1.12.2-0.91.8-1.4-0.5-1.1-1.2-1.4
Body weight0.93.98.50.1-2.5-2.9-1.91.6-0.72.2-1.2-0.3-2.5-2.4-2.6
Epididymis fat weight0.30.71.90.7-0.8-1.40.10.11.00.2-0.11.3-0.6-1.2-0.7
Glucose0.20.41.1-0.90.70.50.40.5-0.3-0.40.5-0.30.81.10.6
Heart weight0.40.62.0-0.8-0.30.0-0.90.8-1.30.8-0.9-1.4-0.20.1-0.2
Left kidney weight1.33.77.7-1.0-2.1-2.8-2.12.2-1.52.3-1.8-1.2-1.9-1.6-2.1
Right kidney weight0.82.44.6-0.4-1.8-2.2-1.71.4-0.91.8-1.3-0.7-1.8-1.6-2.0
Tail length5.617.129.20.5-4.4-4.7-5.42.4-3.35.0-4.0-2.9-4.5-4.6-5.2
Length with tail3.512.925.21.2-4.2-4.0-4.41.5-2.24.1-2.8-1.8-4.5-4.4-5.0
Length without tail0.10.30.60.7-0.40.3-0.0-0.70.5-0.20.70.5-0.6-0.4-0.5
Liver weight, left1.62.68.42.9-1.7-1.6-0.7-1.71.4-0.10.21.6-1.3-2.3-1.5
Liver weight, right2.64.310.73.2-2.3-2.2-1.5-1.51.30.7-0.61.6-2.2-3.3-2.5
Parametrial fat weight0.30.61.8-0.20.2-1.01.00.41.1-0.70.91.30.50.30.8
Retroperitoneal fat weight1.54.812.42.1-2.5-3.5-0.3-0.12.20.80.42.8-2.5-3.1-2.3
Intraocular pressure1.21.75.4-0.81.81.10.8-0.2-0.1-1.30.4-0.22.31.81.9
Extensor digitorum longus weight0.10.41.90.2-0.8-1.40.10.40.60.20.10.8-0.5-0.7-0.3
Soleus weight0.82.28.01.3-2.2-2.8-0.90.10.60.8-0.31.0-1.8-2.2-1.2
Tibialis anterior weight0.31.02.00.4-1.3-1.1-1.00.3-0.31.0-0.8-0.2-1.4-1.4-1.4
Tibia length0.30.83.7-0.60.00.8-0.90.3-1.70.4-0.1-1.9-0.30.5-0.5
Number of licking bursts1.82.26.91.80.50.01.5-1.72.5-1.51.22.60.5-0.30.5
Food consumed during 24 hour testing period1.41.75.7-1.90.1-0.1-1.01.6-2.20.9-0.5-2.40.00.9-0.3
Times rat made contact with spout0.30.30.80.8-0.5-0.9-0.4-0.30.4-0.10.40.5-0.5-0.7-0.7
Mean time between licks in bursts7.09.715.5-0.1-3.8-3.1-3.72.0-2.73.8-2.8-2.4-3.9-3.3-3.5
Mean num. licks in bursts1.62.05.9-1.5-0.6-0.3-1.61.5-2.31.4-1.1-2.4-0.60.1-0.9
Std. dev. time between licks in bursts3.33.97.90.6-2.8-2.5-2.40.8-1.02.1-1.6-0.7-2.6-2.5-2.2
Water consumed over 24 hours0.50.61.10.50.90.80.7-0.90.8-1.10.90.80.80.60.1
Indifference point 0 sec1.22.04.8-1.6-0.9-0.9-1.51.8-2.21.5-1.1-2.2-0.9-0.0-0.5
Indifference point AUC0.60.71.50.1-1.0-1.2-1.00.6-0.41.1-0.8-0.3-1.0-1.1-0.8
Indifference point function ln k0.50.72.0-0.71.01.40.1-0.1-0.6-0.50.4-0.90.81.30.7
Indifference point function log k0.50.72.0-0.71.01.40.1-0.1-0.6-0.50.4-0.90.81.30.7
Delay discounting total patch changes 0 sec1.01.63.6-1.5-0.9-1.0-1.31.8-1.91.4-0.9-1.9-0.8-0.0-0.4
Delay discounting total patch changes 12 sec1.62.13.7-0.1-1.9-1.8-1.61.1-1.11.7-1.3-1.0-1.9-1.5-1.4
Delay discounting total patch changes 18 sec0.81.01.7-0.6-1.1-1.2-1.21.1-1.31.1-1.0-1.2-0.8-0.5-0.4
Delay discounting total patch changes 24 sec1.62.03.6-0.2-1.7-1.9-1.91.2-1.21.7-1.3-1.0-1.6-1.4-1.2
Delay discounting total patch changes 6 sec0.30.41.1-0.9-0.3-0.4-0.40.9-0.80.8-1.1-0.8-0.4-0.00.0
Delay discounting time to switch 0 sec2.33.66.81.91.31.32.3-2.42.6-2.21.72.51.30.51.3
Delay discounting water rate 0 sec1.42.25.0-1.7-0.8-0.6-1.81.8-2.21.7-1.5-2.2-0.9-0.1-0.7
Delay discounting water rate 12 sec1.32.07.6-2.8-0.20.2-0.52.5-1.81.1-1.0-1.8-0.11.0-0.1
Delay discounting water rate 18 sec2.12.86.5-2.2-1.0-1.1-1.72.5-2.12.0-1.4-2.0-1.0-0.2-1.2
Delay discounting water rate 24 sec0.50.62.2-1.50.51.00.30.8-0.7-0.10.4-0.80.61.20.5
Delay discounting water rate 6 sec0.50.83.1-1.8-0.00.2-0.61.5-1.20.5-0.1-1.20.00.80.0
Locomotor activity0.40.61.2-1.1-0.5-0.3-0.51.1-0.90.9-0.9-0.9-0.8-0.1-0.7
Locomotor testing distance1.72.84.6-1.7-1.4-1.4-1.72.2-1.92.0-1.5-1.9-1.8-0.6-1.4
Locomotor testing rearing1.62.44.6-0.3-2.0-1.8-1.81.3-1.21.8-1.1-1.0-2.2-1.5-1.8
Light reinforcement 11.22.25.50.31.40.72.1-0.92.3-1.60.92.31.40.91.5
Light reinforcement 21.72.24.7-2.02.00.91.70.90.3-0.90.70.31.92.22.1
Reaction time number correct0.40.52.4-0.50.91.50.8-0.2-0.1-0.40.5-0.20.71.00.6
Reaction time mean minus median0.50.71.5-0.1-1.2-0.9-0.90.7-0.70.9-0.2-0.6-1.2-0.8-1.0
Reaction time mean minus median AUC0.40.50.9-0.3-0.9-0.3-0.70.5-0.80.7-0.1-0.8-0.9-0.4-0.9
Reaction time num false alarms1.31.85.02.1-0.6-0.30.8-1.82.1-0.90.82.2-0.5-1.1-0.3
Reaction time num false alarms AUC1.11.54.01.9-0.5-0.01.1-1.71.9-1.21.02.0-0.2-0.70.1
Reaction time trials correct on left0.40.52.4-0.50.91.50.8-0.2-0.1-0.40.5-0.20.71.00.6
Reaction time trials on left0.40.62.4-0.51.01.60.9-0.2-0.0-0.50.5-0.20.81.00.6
Reaction time mean1.01.44.32.1-0.9-0.30.3-1.51.5-0.51.01.6-0.8-1.4-1.1
Reaction time mean AUC1.11.54.52.1-0.50.00.5-1.71.6-0.81.21.7-0.5-1.1-0.8
Median of all reaction times1.41.95.42.3-0.40.10.8-1.91.9-0.91.32.0-0.4-1.1-0.8
Reaction time omissions0.30.41.20.6-0.3-0.10.9-0.31.0-0.51.01.1-0.3-0.2-0.2
Reaction time false alarm rate1.01.54.31.8-0.8-0.80.7-1.41.9-0.90.82.1-0.6-1.0-0.1
Reaction time premature initiation rate2.53.47.4-0.4-2.1-2.7-2.11.7-1.42.2-1.7-1.2-1.9-1.8-1.9
Reaction time premature initiations1.01.42.3-0.7-1.3-1.5-1.21.4-1.21.5-0.9-1.1-1.2-0.9-1.1
Std. dev. reaction times1.11.53.51.3-1.8-1.4-1.0-0.30.10.70.10.3-1.6-1.9-1.6
Reaction time trials completed0.40.62.4-0.51.01.60.9-0.2-0.0-0.50.5-0.20.81.00.6
Reaction time trials AUC0.20.31.6-0.40.71.30.7-0.1-0.0-0.30.4-0.20.50.70.3
Social response proportion0.40.41.20.4-1.1-0.80.60.10.80.1-0.11.0-0.8-0.7-0.3
Social responses1.21.64.61.0-2.2-1.4-0.4-0.10.70.7-0.30.9-2.1-1.8-1.3
Social time1.41.93.50.90.91.61.9-1.51.8-1.41.21.70.60.61.4
Conditioned locomotion0.40.41.51.2-0.50.70.1-1.10.5-0.1-0.30.5-0.7-0.8-0.5
Cocaine response after cond. corrected0.60.72.60.90.1-0.40.8-0.71.5-0.70.51.60.1-0.40.1
Cocaine response after cond. not corrected0.40.51.00.00.70.00.9-0.20.9-0.80.61.00.80.50.7
Cocaine response before conditioning1.31.64.3-2.11.20.90.11.3-1.40.0-0.1-1.61.31.71.2
Saline control response2.33.06.2-0.0-2.0-1.5-2.51.0-1.92.0-1.3-1.9-1.9-1.6-2.0
Condit. Reinf. active minus inactive responses6.37.813.1-1.7-2.6-2.4-3.62.8-3.63.3-2.2-3.5-2.6-1.5-2.6
Condit. Reinf. active-inactive response ratio1.11.12.7-1.1-0.5-0.8-1.31.4-1.61.1-0.7-1.6-0.5-0.1-0.6
Condit. Reinf. active responses8.611.919.0-1.7-3.6-3.2-4.43.3-4.24.1-2.5-4.0-3.6-2.3-3.4
Condit. Reinf. inactive responses5.56.810.7-0.7-3.3-2.6-3.22.2-2.83.1-1.6-2.6-3.3-2.1-2.7
Condit. Reinf. lever presses10.814.929.6-3.3-3.3-2.8-4.54.6-5.44.5-3.0-5.4-3.3-1.3-3.0
Condit. Reinf. lever reinforcers received8.612.219.8-1.8-3.5-3.2-4.43.4-4.44.1-2.4-4.3-3.5-2.1-3.4
Pavlov. Cond. lever latency11.415.631.64.12.92.54.2-5.15.6-4.63.45.62.90.82.7
Pavlov. Cond. magazine entry latency2.83.210.6-3.3-0.3-0.2-0.73.1-2.41.6-1.3-2.5-0.41.0-0.3
Pavlov. Cond. change in total contacts9.313.028.6-4.2-2.3-1.7-3.74.8-5.34.2-3.0-5.3-2.4-0.3-2.2
Pavlov. Cond. index score8.511.123.2-3.9-2.2-1.8-3.24.6-4.83.8-2.9-4.8-2.3-0.3-2.1
Pavlov. Cond. latency score7.69.620.2-3.9-1.9-1.6-2.84.5-4.53.5-2.6-4.5-1.9-0.0-1.8
Pavlov. Cond. lever contacts11.415.932.8-4.0-3.0-2.5-4.35.0-5.74.6-3.3-5.7-3.0-0.9-2.8
Pavlov. Cond. magazine entry number4.35.313.23.60.60.41.5-3.63.4-2.31.93.50.8-0.80.6
Pavlov. Cond. intertrial magazine entries1.01.32.81.1-1.5-1.7-1.3-0.1-0.20.9-0.3-0.1-1.4-1.7-1.5
Pavlov. Cond. lever-magazine prob. diff.8.310.821.9-3.8-2.2-1.8-3.14.5-4.73.8-2.9-4.6-2.3-0.4-2.1
Pavlov. Cond. response bias11.415.733.5-4.4-2.7-2.3-4.05.3-5.84.6-3.3-5.8-2.8-0.5-2.5
Conditioned reinforcement - actives0.30.31.0-0.60.10.4-0.30.3-0.9-0.1-0.2-1.00.40.70.2
Conditioned reinforcement - inactives0.40.41.61.3-0.6-0.4-0.1-0.90.7-0.20.30.7-0.7-0.8-0.5
Conditioned locomotion0.81.02.8-1.70.40.6-0.21.1-1.50.2-0.5-1.60.51.30.8
Intermittent access intake day 1-15 change0.80.83.6-1.90.1-0.00.01.6-0.90.3-0.5-0.90.51.10.8
Intermittent access intake escalation0.80.83.3-1.80.20.10.21.4-0.80.1-0.2-0.80.61.20.9
Intermittent access intake escalation 20.20.20.8-0.6-0.6-0.90.10.80.00.00.00.2-0.10.10.2
Intermitt. access day 1 inactive lever presses0.91.03.31.8-0.4-0.50.3-1.41.2-0.91.11.3-0.3-0.8-0.3
Intermitt. access day 15 inactive lever presses0.10.20.5-0.50.40.5-0.30.1-0.60.1-0.3-0.70.10.40.3
Intermitt. access escalation Index0.10.10.50.3-0.4-0.7-0.5-0.1-0.20.1-0.0-0.2-0.5-0.4-0.4
Intermittent access day 1 total infusions0.70.81.70.1-0.5-0.6-1.30.4-1.30.9-0.9-1.3-0.9-0.7-0.9
Intermittent access day 15 total infusions0.50.51.8-0.8-0.4-0.2-0.90.8-1.30.6-0.5-1.3-0.30.1-0.2
Intermittent access terminal intake (last 3 days)0.60.61.5-0.5-0.7-0.6-1.00.8-1.20.8-0.7-1.2-0.7-0.2-0.5
Intermittent access total infusions0.40.51.2-0.2-0.5-0.5-1.00.5-1.10.6-0.5-1.1-0.6-0.3-0.6
Intermittent access day 1 locomotion0.10.10.40.60.40.4-0.2-0.7-0.2-0.40.3-0.30.10.10.1
Intermittent access day 15 total locomotion0.50.51.3-1.10.60.4-0.10.8-1.0-0.10.2-1.10.41.00.7
Intermittent access total locomotion0.20.31.1-0.5-0.00.2-0.60.5-1.00.4-0.2-1.1-0.40.2-0.1
Intermittent access standard deviation0.10.10.3-0.6-0.5-0.30.30.60.1-0.20.30.2-0.10.30.4
Cocaine induced anxiety2.02.35.22.10.30.71.2-2.32.2-1.71.82.20.5-0.20.5
Post-drug Anxiety0.70.73.01.7-0.5-0.4-0.4-1.30.8-0.00.00.8-0.7-1.2-0.7
Baseline Anxiety1.61.63.1-0.4-0.5-1.1-1.71.0-1.71.6-1.6-1.7-1.0-0.9-1.1
Lifetime Intake0.70.72.0-0.6-0.4-0.4-1.10.9-1.40.9-0.8-1.4-0.6-0.2-0.6
Incentive Sensitization - Responses1.01.01.90.2-0.8-1.0-1.40.6-1.21.0-0.6-1.1-1.2-1.0-1.3
Incentive Sensitization - Breakpoint0.70.71.3-0.0-0.6-0.9-1.10.6-1.10.8-0.4-1.1-1.0-0.7-1.0
Progressive ratio test 1 active lever presses0.00.00.1-0.00.40.3-0.1-0.0-0.20.0-0.4-0.20.00.10.1
Progressive ratio test 1 breakpoint0.00.00.10.10.20.1-0.2-0.0-0.20.1-0.4-0.2-0.1-0.1-0.0
Progressive ratio test 1 inactive lever presses0.00.00.10.2-0.0-0.1-0.3-0.0-0.4-0.00.3-0.4-0.2-0.1-0.2
Progressive ratio test 2 active lever presses0.30.30.90.3-0.2-0.4-0.90.1-0.80.4-0.3-0.8-0.7-0.5-0.6
Progressive ratio test 2 breakpoint0.40.41.20.3-0.3-0.5-1.10.2-0.90.6-0.4-0.9-0.8-0.6-0.7
Progressive ratio test 2 inactive lever presses0.10.10.6-0.10.30.5-0.2-0.0-0.7-0.00.1-0.8-0.10.2-0.1
Total sessions with >9 infusions1.82.05.2-2.20.30.3-0.81.9-2.21.1-1.5-2.30.20.90.1
Short access day 1 total inactive lever presses0.40.52.01.40.40.40.1-1.30.5-0.80.80.4-0.0-0.20.1
Short access day 10 total inactive lever presses0.60.61.60.90.30.30.9-1.01.0-1.11.31.00.40.20.5
Short access day 1 total infusions1.21.32.9-0.7-0.8-0.6-1.51.1-1.71.3-1.2-1.7-0.9-0.5-1.0
Short access day 10 total infusions1.01.12.4-0.5-0.7-0.9-1.41.0-1.51.1-0.9-1.5-0.9-0.5-0.8
Short access total infusions0.91.02.2-0.8-0.4-0.6-1.21.1-1.51.2-1.2-1.5-0.8-0.4-0.7
Short access day 1 locomotion1.01.02.5-1.31.11.00.40.6-1.0-0.50.0-1.11.31.61.2
Short access day 10 total locomotion0.10.20.5-0.5-0.4-0.30.00.7-0.30.10.3-0.2-0.70.1-0.1
Short access total locomotion0.10.10.3-0.30.40.40.10.2-0.3-0.20.1-0.40.20.50.3
Compulsive drug intake1.11.11.90.21.41.11.1-0.80.7-1.31.00.61.41.11.2
One hour access (0.3 mA shock)0.70.81.9-1.0-0.8-0.9-0.91.4-1.20.9-0.4-1.2-0.8-0.1-0.6
One hour access (shock baseline)1.31.52.2-0.6-1.4-1.2-1.51.3-1.41.4-0.9-1.3-1.4-0.8-1.3
Number of responses in last shaping day0.40.41.01.0-0.5-0.6-0.8-0.5-0.10.3-0.2-0.1-0.8-1.0-0.7
Context. condit. distance diff. score1.82.15.6-2.20.10.3-1.11.8-2.21.6-1.6-2.4-0.20.5-0.7
Locomotion velocity, session 11.31.42.6-0.71.41.31.4-0.10.5-1.20.60.41.61.61.6
Locomotion distance, session 10.50.72.6-1.60.40.50.01.2-1.00.10.1-1.00.51.20.6
Locomotion velocity, session 20.20.31.2-1.1-0.2-0.20.31.1-0.40.10.3-0.30.10.60.5
Locomotion distance, session 20.30.52.3-1.5-0.20.10.11.3-0.70.40.2-0.6-0.20.70.2
Locomotion velocity, session 30.40.41.4-0.70.30.9-0.50.4-1.00.4-0.5-1.20.20.50.2
Locomotion distance, session 30.70.82.0-1.10.90.9-0.20.5-1.20.1-0.4-1.40.91.10.8
Stereotopy head waving bouts, day 30.40.51.30.9-1.1-0.8-0.4-0.30.30.40.00.4-1.1-1.1-0.7
Stereotopy head waving duration, day 30.10.10.3-0.6-0.00.20.00.4-0.40.2-0.0-0.4-0.10.30.3
Locomotion velocity, session 70.30.30.8-0.60.90.70.60.10.3-0.40.30.30.90.80.4
Locomotion distance, session 70.10.10.30.5-0.1-0.10.1-0.40.6-0.10.20.6-0.0-0.4-0.2
Stereotopy head waving bouts, day 71.41.65.5-1.50.10.1-1.31.4-2.21.0-0.9-2.30.00.70.1
Stereotopy head waving duration, day 71.51.96.0-1.8-0.1-0.3-1.31.8-2.41.2-1.1-2.5-0.10.70.1
Locomotion velocity, session 80.80.92.6-1.0-0.40.2-1.11.0-1.51.2-0.9-1.6-0.40.0-0.7
Locomotion distance, session 81.62.46.1-2.5-0.5-0.1-1.02.3-2.31.7-1.3-2.3-0.70.4-0.6
Degree of sensitization distance2.02.04.51.1-2.0-1.8-0.8-0.00.61.0-0.20.9-2.0-2.1-2.0
Degree of sensitization stereotypy2.93.210.6-2.20.00.0-1.82.0-3.11.6-1.6-3.3-0.10.7-0.2
Condit. Reinf. active minus inactive responses1.01.12.30.5-1.2-0.9-1.50.2-0.61.1-0.7-0.6-1.2-1.3-1.5
Condit. Reinf. active-inactive response ratio1.41.53.40.8-1.3-1.1-1.80.1-0.91.3-1.0-0.8-1.3-1.6-1.8
Condit. Reinf. active responses0.50.61.31.0-1.1-0.6-0.9-0.4-0.10.50.0-0.0-1.1-1.1-1.0
Condit. Reinf. inactive responses0.20.20.70.5-0.20.20.5-0.50.6-0.50.80.6-0.10.00.4
Incentive salience index mean0.60.71.40.7-1.2-0.9-1.2-0.0-0.40.70.0-0.3-1.1-1.1-1.1
Condit. Reinf. lever presses0.10.21.50.3-0.4-0.5-0.1-0.1-0.0-0.31.2-0.0-0.00.00.2
Time in familiar zone, hab. session 10.30.20.6-0.3-0.3-0.4-0.30.6-0.40.7-0.8-0.4-0.4-0.4-0.6
Time in novel zone, hab. session 10.20.20.70.8-0.00.10.0-0.80.7-0.40.30.70.1-0.3-0.2
Total zone transitions, hab. session 10.40.61.4-1.00.91.10.30.3-0.5-0.20.4-0.70.91.20.9
Total locomotion distance, hab. session 11.01.43.31.0-1.6-1.3-0.8-0.10.50.9-0.80.8-1.5-1.8-1.8
Locomotion velocity, hab. session 10.71.12.40.8-1.5-1.1-0.6-0.00.50.8-0.60.7-1.5-1.6-1.4
Time in familiar zone, hab. session 22.02.13.9-0.4-1.1-0.9-2.00.9-1.61.9-2.0-1.5-1.3-1.2-1.8
Time in novel zone, hab. session 21.31.32.8-0.50.80.71.7-0.10.9-1.31.50.91.11.41.5
Total zone transitions, hab. session 21.21.64.6-2.10.20.4-0.91.7-2.01.1-0.7-2.1-0.10.9-0.2
Total locomotion distance, hab. session 22.33.17.70.1-2.2-1.6-1.61.0-0.62.1-1.5-0.4-2.6-2.1-2.8
Locomotion velocity, hab. session 22.43.27.70.2-2.4-1.7-1.61.0-0.52.1-1.4-0.2-2.7-2.2-2.8
Novel to familiar place preference ratio0.80.82.21.2-1.10.0-0.9-0.8-0.10.6-0.4-0.2-1.5-1.3-1.1
Novelty place preference0.80.82.41.1-1.20.1-0.9-0.7-0.20.7-0.5-0.2-1.5-1.3-1.1
Time in novel zone, NPP test0.91.02.71.0-1.30.0-1.1-0.6-0.30.8-0.7-0.4-1.7-1.4-1.3
Total zone transitions, NPP test0.60.82.5-1.60.50.50.61.0-0.5-0.41.0-0.60.81.51.0
Total locomotion distance, NPP test0.60.82.1-0.2-1.5-1.30.00.80.60.7-0.00.8-1.3-1.0-0.9
Locomotion velocity, NPP test0.40.61.5-0.1-1.2-1.20.30.60.90.40.31.1-1.0-0.8-0.7
Pavlov. Cond. lever latency0.50.61.30.10.90.91.1-0.51.1-0.70.01.10.70.50.6
Pavlov. Cond. magazine entry latency2.12.75.2-1.4-1.2-1.4-1.82.0-2.32.0-1.2-2.2-1.4-0.7-1.3
Pavlov. Cond. change in total contacts0.90.92.40.2-0.9-0.9-1.50.4-1.31.0-0.6-1.3-0.9-0.8-0.8
Pavlov. Cond. index score1.52.04.2-0.9-1.3-1.5-1.71.5-2.01.6-0.7-2.0-1.2-0.6-0.9
Pavlov. Cond. latency score1.41.83.7-0.7-1.3-1.4-1.71.3-1.91.4-0.6-1.9-1.2-0.7-0.9
Pavlov. Cond. lever contacts0.60.71.4-0.3-0.9-1.2-1.10.7-1.10.8-0.1-1.1-0.6-0.5-0.5
Pavlov. Cond. magazine entry number1.72.15.11.31.01.21.7-1.72.3-1.60.72.31.00.30.8
Pavlov. Cond. intertrial magazine entries0.50.71.61.00.70.60.6-1.31.1-1.00.81.00.40.10.2
Pavlov. Cond. lever-magazine prob. diff.1.21.53.4-0.9-1.0-1.3-1.51.3-1.91.3-0.6-1.8-0.9-0.4-0.6
Pavlov. Cond. response bias0.70.91.8-0.6-0.9-1.1-1.11.1-1.31.1-0.4-1.3-0.8-0.5-0.7
Bone: apparent density0.40.61.30.21.10.70.5-0.70.3-0.90.70.21.10.81.1
Bone surface0.30.51.9-0.1-0.4-0.6-1.40.3-1.20.6-0.5-1.2-0.3-0.3-0.2
Bone volume0.20.31.20.1-0.5-0.4-1.10.1-0.80.5-0.3-0.9-0.5-0.4-0.3
Bone: connectivity density1.01.64.4-0.91.71.01.0-0.00.1-1.30.8-0.02.11.82.0
Bone: cortical apparent density0.81.02.91.5-0.7-0.40.1-1.11.5-0.30.31.7-0.7-1.2-0.7
Bone: cortical area0.71.12.60.1-1.5-1.0-1.30.5-0.71.1-0.5-0.7-1.6-1.2-1.3
Bone: cortical porosity0.20.20.60.20.40.8-0.1-0.5-0.6-0.3-0.0-0.70.40.50.5
Bone: cortical porosity0.20.20.70.20.30.8-0.2-0.6-0.5-0.3-0.0-0.70.30.40.3
Bone: cortical thickness0.10.10.4-0.2-0.10.30.50.00.5-0.30.60.5-0.10.20.1
Bone: cortical thickness0.00.10.2-0.0-0.40.2-0.1-0.0-0.10.2-0.1-0.2-0.5-0.1-0.2
Bone: cortical tissue density0.71.02.91.5-0.6-0.30.2-1.11.6-0.30.31.7-0.6-1.1-0.7
Bone: elastic displacement2.22.54.70.11.81.62.2-1.01.5-1.81.51.41.81.51.8
Bone: elastic work3.44.58.2-0.42.61.92.9-0.91.8-2.41.61.72.62.32.8
Bone: endosteal estimation1.43.06.50.3-1.8-2.2-2.50.9-1.61.9-1.5-1.5-1.9-1.9-1.7
Bone: endosteal perimeter1.63.26.7-0.2-1.9-2.2-2.61.3-1.92.0-1.4-1.8-2.0-1.6-1.5
Bone: final force0.50.92.91.7-0.8-0.1-0.8-1.30.50.1-0.20.4-1.2-1.3-0.9
Bone: final moment0.50.72.11.4-0.9-0.2-0.8-1.00.20.3-0.40.2-1.3-1.3-0.9
Bone: marrow area1.22.75.70.4-1.8-2.2-2.40.7-1.41.7-1.4-1.3-1.8-1.8-1.6
Bone: maximum diameter1.83.36.3-0.4-2.0-1.7-2.51.4-2.12.1-1.4-2.0-2.1-1.5-1.8
Bone: maximum force0.30.51.41.2-0.7-0.2-0.9-0.80.00.2-0.30.0-0.9-1.0-0.7
Bone: maximum moment0.20.40.90.8-0.7-0.4-0.9-0.4-0.20.4-0.5-0.2-1.0-0.9-0.6
Bone: minimum diameter1.93.56.90.8-2.5-2.3-2.20.7-0.91.9-1.1-0.7-2.6-2.4-2.4
Bone: periosteal estimation1.22.54.90.2-1.9-2.0-2.20.9-1.41.7-1.1-1.3-1.9-1.6-1.6
Bone: periosteal perimeter1.32.24.0-0.4-1.8-1.6-2.01.2-1.61.7-1.1-1.5-1.8-1.2-1.3
Bone: post-yield work0.20.30.8-0.3-0.3-0.3-0.90.3-0.50.6-0.7-0.5-0.4-0.3-0.5
Bone: stiffness1.21.95.92.4-1.5-0.8-1.2-1.50.70.3-0.40.7-1.7-2.1-1.4
Bone: tissue strength2.02.04.1-1.11.91.81.6-0.10.4-1.30.60.31.82.01.8
Bone: trabecular number1.32.03.20.11.71.31.5-1.01.1-1.71.51.01.81.41.7
Bone: trabecular spacing0.50.62.7-1.6-0.1-0.3-0.11.4-0.90.4-0.0-0.9-0.00.70.2
Bone: trabecular thickness0.70.92.81.7-0.8-0.1-0.8-1.20.30.4-0.40.3-1.1-1.4-1.1
Bone: trabecular tissue density2.63.79.63.1-2.3-1.4-1.2-1.61.20.6-0.21.4-2.4-3.0-2.2
Breakpoint value in progressive ratio session0.30.30.7-0.70.60.60.80.10.2-0.40.50.20.70.90.4
Distance traveled before self-admin0.40.41.70.1-0.00.01.1-0.31.2-0.50.01.30.10.10.7
Distance traveled after self-admin0.40.41.7-1.00.51.30.40.3-0.2-0.0-0.3-0.40.31.00.7
Delta time in closed arm before/after self-admin1.51.43.81.5-1.2-1.7-0.3-0.51.20.4-0.41.5-1.1-1.9-1.2
Delta time in open arm before/after self-admin1.41.33.7-0.4-0.5-0.7-1.80.9-1.91.2-0.9-1.9-1.0-0.4-0.7
Diff in mean of infusions in LGA sessions1.11.24.92.2-0.1-0.10.3-1.91.4-0.80.81.4-0.1-0.8-0.0
Extinction: sum of active levers before priming0.10.10.10.10.20.10.3-0.10.3-0.30.30.30.30.1-0.1
Active lever presses in extinction session 61.21.22.7-1.61.11.20.00.8-1.30.0-0.1-1.50.61.60.9
Delta distance traveled before/after self-admin1.31.44.4-0.5-0.70.4-1.90.5-1.91.3-0.9-2.1-0.9-0.2-1.1
Delta ambulatory time before/after self-admin0.91.03.9-0.70.00.8-1.40.4-1.70.9-0.7-2.0-0.30.3-0.6
Time in closed arm before self-admin1.41.64.5-2.11.11.5-0.21.2-1.80.6-0.7-2.10.31.40.3
Time in closed arm after self-admin0.60.61.20.51.11.01.0-1.10.9-0.80.20.80.60.30.6
Time in open arm before self-admin2.93.19.31.70.20.22.1-1.82.9-2.01.63.01.10.11.1
Time in open arm after self-admin0.40.41.10.6-1.1-1.0-0.70.10.00.3-0.40.2-0.6-0.8-0.5
Sum of active levers in priming session hrs 5-60.10.10.5-0.7-0.20.60.10.4-0.20.30.2-0.3-0.40.3-0.2
Time to tail flick, vehicle, before self-admin0.10.10.4-0.50.10.3-0.40.3-0.50.4-0.3-0.6-0.20.1-0.2
Time to tail flick, vehicle, after self-admin0.80.93.8-0.9-0.00.4-1.10.6-1.80.5-0.6-2.00.10.60.2
Time to tail flick, test, before self-admin1.21.23.1-0.3-0.9-1.3-1.80.8-1.31.2-0.4-1.3-1.1-0.7-0.9
Time to tail flick, test, after self-admin2.52.54.30.4-1.6-2.0-2.10.7-1.11.8-1.5-1.0-1.9-1.9-1.9
Delta time to tail flick, vehicle, before/after SA0.30.30.9-0.40.30.2-0.20.3-0.8-0.30.2-0.90.80.80.7
Delta time to tail flick, test, before/after SA0.10.10.30.2-0.1-0.10.4-0.10.5-0.0-0.20.6-0.1-0.3-0.1
Ambulatory time before self-admin0.60.61.60.30.40.41.2-0.61.3-0.80.21.30.50.30.9
Ambulatory time after self-admin0.50.63.0-0.90.81.70.1-0.0-0.50.1-0.6-0.70.41.00.5
Total heroin consumption0.50.61.7-1.3-0.40.1-0.41.1-1.00.9-0.3-1.0-0.60.2-0.7
Area under the delay curve0.40.41.51.2-0.2-0.20.1-1.00.7-0.60.80.70.1-0.40.1
Delay disc. indifference point, 0s delay0.50.51.0-0.4-0.9-0.7-0.80.8-0.80.8-0.2-0.8-1.0-0.4-0.5
Delay disc. indifference point, 16s delay0.50.52.51.60.20.50.1-1.50.7-0.50.10.6-0.0-0.6-0.1
Delay disc. indifference point, 2s delay0.70.71.70.5-1.2-1.1-1.30.3-0.80.8-0.2-0.7-1.0-0.9-0.8
Delay disc. indifference point, 24s delay1.11.02.91.70.20.80.8-1.71.4-0.90.51.40.1-0.5-0.2
Delay disc. indifference point, 4s delay1.31.42.50.2-1.6-1.6-1.50.7-0.81.3-0.5-0.7-1.6-1.4-1.3
Delay disc. indifference point, 8s delay0.20.20.60.6-0.1-0.10.2-0.60.5-0.60.80.50.4-0.00.3
Delay discount exponential model param0.40.41.3-1.10.10.2-0.30.9-0.80.7-1.0-0.8-0.20.3-0.2
Delay discount hyperbolic model param0.30.31.1-1.00.40.50.00.7-0.50.5-0.8-0.60.00.5-0.0
Fecal boli incidents, locomotor time 11.21.33.31.30.30.61.1-1.60.9-1.81.60.81.00.61.2
Change in fecal boli incidents, locomotor task0.20.20.8-0.10.50.2-0.30.20.10.6-0.90.2-0.0-0.4-0.5
Time >=10cm from walls, locomotor time 10.20.21.0-0.3-0.10.2-0.80.1-0.90.4-0.2-1.0-0.1-0.0-0.3
Bouts of movement, locomotor time 10.10.20.60.8-0.5-0.1-0.5-0.6-0.20.0-0.1-0.2-0.5-0.40.1
Total resting periods, locomotor time 10.20.20.70.60.20.50.1-0.80.2-0.60.60.00.10.20.7
Rest time, locomotor task time 10.20.20.80.60.50.8-0.2-0.9-0.1-0.2-0.2-0.20.60.10.2
Distance moved, locomotor task time 10.40.51.8-0.3-0.8-1.3-0.40.8-0.10.50.10.1-1.0-0.5-0.8
Vertical activity count, locomotor time 10.50.51.60.4-0.9-1.1-0.50.3-0.10.40.60.1-1.2-0.8-1.2
Time >=10cm from walls, locomotor time 22.32.44.70.0-1.4-0.5-2.20.7-1.61.9-1.8-1.6-1.7-1.5-2.0
Bouts of movement, locomotor time 21.92.15.11.7-2.0-1.4-1.4-0.5-0.11.1-1.40.1-1.8-2.3-1.5
Total resting periods, locomotor time 21.41.53.81.8-1.6-1.2-0.9-0.80.30.7-1.00.5-1.4-2.0-1.1
Rest time, locomotor task time 21.61.93.71.01.21.11.9-1.51.9-1.50.71.91.20.51.3
Distance moved, locomotor task time 22.52.95.4-1.1-1.7-1.6-2.31.8-2.01.9-0.9-2.0-1.9-0.9-1.7
Vertical activity count, locomotor time 21.31.42.90.6-1.5-1.2-1.50.3-0.71.1-0.3-0.6-1.7-1.5-1.7
Weight adjusted by age1.11.22.0-0.5-1.2-1.3-1.31.1-0.91.4-1.4-0.8-1.0-0.9-1.1
Seeking ratio, delayed vs. immediate footshock1.61.93.70.41.10.81.4-1.21.4-1.91.71.41.61.21.6
Locomotion in novel chamber1.01.32.5-1.00.81.21.5-0.10.5-1.31.50.41.31.61.3
Locomotion in novel chamber post-restriction0.70.82.0-1.30.60.2-0.30.8-1.3-0.10.3-1.40.61.30.8
Progressive ratio0.40.41.1-0.60.80.40.70.3-0.1-0.50.6-0.20.91.01.0
Food seeking constrained by brief footshock1.62.03.4-0.4-1.5-1.5-1.71.4-1.51.8-1.1-1.3-1.5-1.2-1.6
Seeking ratio, punishment vs. effort1.92.34.40.1-2.0-1.7-1.80.9-0.91.8-1.3-0.8-1.9-1.8-2.1
Run reversals in cocaine runway, females2.22.15.7-0.1-2.1-2.4-0.91.4-0.31.6-1.00.1-1.7-1.8-1.7
Run reversals in cocaine runway, males0.60.61.40.70.70.60.4-0.90.6-1.01.20.50.90.40.7
Latency to leave start box in cocaine runway0.50.61.91.10.6-0.30.4-0.91.3-0.7-0.31.40.4-0.30.7
Latency to leave start box in cocaine runway, F0.60.62.11.4-0.4-0.9-0.2-0.81.0-0.2-0.41.2-0.4-1.0-0.1
Latency to leave start box in cocaine runway, M1.01.02.00.01.40.81.0-0.70.8-1.20.40.71.41.01.4
Cd content in liver0.30.30.80.8-0.1-0.70.3-0.50.8-0.50.60.90.3-0.30.5
Co content in liver2.32.74.80.6-2.0-1.4-2.20.5-1.51.8-1.5-1.5-2.0-1.8-1.9
Cu content in liver1.31.63.00.5-1.6-1.4-1.70.5-1.11.3-1.1-1.0-1.5-1.4-1.5
Fe content in liver0.20.21.11.0-0.2-0.2-0.2-0.80.2-0.10.10.1-0.3-0.6-0.5
K content in liver0.40.40.70.7-0.8-0.30.5-0.30.7-0.30.80.8-0.7-0.5-0.5
Mg content in liver0.10.10.3-0.3-0.5-0.10.00.4-0.20.10.3-0.2-0.4-0.0-0.3
Mn content in liver2.12.43.90.31.71.72.0-1.21.6-1.91.51.41.71.41.6
Na content in liver0.20.20.6-0.40.40.2-0.20.3-0.7-0.00.3-0.70.30.50.2
Rb content in liver0.30.41.00.1-0.6-0.6-1.00.3-1.00.5-0.1-1.0-0.5-0.4-0.6
Se content in liver3.03.65.81.81.51.52.0-2.32.4-2.32.02.31.60.71.5
Sr content in liver1.11.02.9-1.71.10.70.91.0-0.3-0.2-0.1-0.31.21.41.2
Zn content in liver1.92.15.2-2.1-0.9-0.8-1.12.3-2.11.4-1.2-2.1-0.50.3-0.2