Hub : Genes

Ntn4

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	BLA	gene expression	ENSRNOG00000005573	0.06	0.04	4.7e-03	0.02	0.03	0	0.01	4.4e-02	8.1e-03	1.6e-01	6.5e-02
2	LHb	gene expression	ENSRNOG00000005573	0.21	0.12	5.4e-03	0.04	0.06	0.03	0.05	3.7e-02	1.6e-02	6.8e-02	2.9e-02
3	Liver	gene expression	ENSRNOG00000005573	0.1	0.05	8.3e-11	0.05	0.06	0.05	0.05	2.9e-06	4.3e-07	4.7e-06	1.3e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
BMI with tail	3.2	10.5	11.6	3.0	-3.3	-3.4
BMI without tail	7.4	15.4	17.7	3.4	-4.1	-4.2
Body weight	16.1	68.3	84.2	7.3	-8.2	-9.2
Epididymis fat weight	2.7	6.3	8.1	2.8	-1.9	-2.7
Glucose	0.1	0.2	0.3	0.2	-0.3	-0.6
Heart weight	0.5	0.8	1.7	0.5	-1.3	-0.6
Left kidney weight	4.0	11.3	12.2	3.1	-3.5	-3.5
Right kidney weight	3.0	8.7	10.2	2.5	-3.1	-3.2
Tail length	11.3	34.1	43.5	5.1	-5.7	-6.6
Length with tail	14.8	54.2	66.4	6.9	-7.0	-8.1
Length without tail	7.3	15.9	18.5	3.9	-3.7	-4.3
Liver weight, left	0.7	1.1	1.7	1.3	-0.7	-1.1
Liver weight, right	2.8	4.7	6.1	2.1	-1.8	-2.5
Parametrial fat weight	0.1	0.2	0.6	0.3	-0.3	-0.8
Retroperitoneal fat weight	3.1	10.2	15.2	3.9	-2.3	-3.2
Intraocular pressure	3.4	4.9	6.4	-2.0	2.0	2.5
Extensor digitorum longus weight	0.3	1.4	2.2	0.5	-1.5	-1.3
Soleus weight	0.4	1.1	1.9	0.9	-0.8	-1.4
Tibialis anterior weight	0.0	0.1	0.2	-0.4	-0.2	-0.2
Tibia length	8.9	25.0	34.6	5.9	-3.9	-5.0
Number of licking bursts	0.0	0.0	0.1	-0.3	0.2	0.2
Food consumed during 24 hour testing period	0.0	0.1	0.1	0.1	-0.3	-0.2
Times rat made contact with spout	0.2	0.3	0.7	0.4	-0.8	0.0
Mean time between licks in bursts	0.9	1.3	1.8	1.3	-1.1	-0.8
Mean num. licks in bursts	0.1	0.1	0.2	0.0	-0.1	0.5
Std. dev. time between licks in bursts	0.1	0.1	0.2	0.4	-0.1	0.1
Water consumed over 24 hours	0.5	0.5	0.9	-0.0	-1.0	-0.8
Indifference point 0 sec	0.1	0.2	0.5	-0.7	0.1	0.0
Indifference point AUC	0.3	0.3	0.6	-0.4	-0.8	-0.4
Indifference point function ln k	0.0	0.1	0.1	0.4	0.2	0.0
Indifference point function log k	0.0	0.1	0.1	0.4	0.2	0.0
Delay discounting total patch changes 0 sec	0.1	0.2	0.5	-0.7	0.1	-0.1
Delay discounting total patch changes 12 sec	0.8	1.0	1.7	0.0	-1.3	-1.2
Delay discounting total patch changes 18 sec	0.3	0.5	1.1	-1.1	-0.2	0.4
Delay discounting total patch changes 24 sec	0.5	0.7	1.3	-0.1	-1.2	-0.8
Delay discounting total patch changes 6 sec	0.2	0.3	0.8	-0.9	-0.0	0.4
Delay discounting time to switch 0 sec	0.1	0.1	0.2	-0.3	-0.1	-0.4
Delay discounting water rate 0 sec	1.3	2.1	4.9	2.2	-0.6	-1.1
Delay discounting water rate 12 sec	2.1	3.1	4.0	1.4	-2.0	-1.9
Delay discounting water rate 18 sec	0.1	0.1	0.3	0.5	0.4	0.2
Delay discounting water rate 24 sec	3.0	4.2	8.1	2.9	-1.2	-1.7
Delay discounting water rate 6 sec	6.4	9.4	13.9	3.7	-2.2	-3.1
Locomotor activity	5.9	9.3	10.0	3.0	-3.0	-3.2
Locomotor testing distance	1.6	2.7	3.8	1.9	-1.4	-1.5
Locomotor testing rearing	0.0	0.1	0.1	0.4	-0.0	-0.1
Light reinforcement 1	0.2	0.4	1.0	1.0	-0.2	-0.3
Light reinforcement 2	0.6	0.8	1.5	-1.2	0.5	0.8
Reaction time number correct	0.0	0.0	0.1	0.2	-0.2	0.0
Reaction time mean minus median	0.7	0.9	1.3	-1.1	0.6	1.1
Reaction time mean minus median AUC	1.0	1.2	1.9	-1.0	0.9	1.4
Reaction time num false alarms	0.9	1.3	3.3	-1.8	0.5	0.6
Reaction time num false alarms AUC	1.3	1.8	4.5	-2.1	0.5	0.9
Reaction time trials correct on left	0.0	0.0	0.1	0.2	-0.2	0.0
Reaction time trials on left	0.0	0.0	0.0	0.2	-0.1	0.1
Reaction time mean	0.2	0.3	0.6	-0.2	0.8	0.5
Reaction time mean AUC	0.1	0.2	0.3	-0.2	0.5	0.3
Median of all reaction times	0.1	0.1	0.2	0.3	0.5	-0.1
Reaction time omissions	2.9	3.9	4.4	-2.0	1.8	2.1
Reaction time false alarm rate	1.2	1.7	3.9	-2.0	0.7	0.9
Reaction time premature initiation rate	0.1	0.1	0.4	0.6	0.0	0.1
Reaction time premature initiations	0.1	0.1	0.4	0.6	-0.2	0.0
Std. dev. reaction times	1.0	1.3	1.6	-1.1	1.0	1.2
Reaction time trials completed	0.0	0.0	0.0	0.2	-0.1	0.1
Reaction time trials AUC	0.0	0.1	0.1	0.4	-0.2	-0.1
Social response proportion	7.2	7.9	9.9	2.8	-2.4	-3.1
Social responses	3.7	4.8	7.7	2.8	-1.5	-2.1
Social time	0.3	0.5	0.7	0.4	-0.7	-0.9
Conditioned locomotion	0.2	0.2	0.7	0.2	0.0	-0.8
Cocaine response after cond. corrected	0.4	0.4	0.7	-0.5	-0.8	-0.5
Cocaine response after cond. not corrected	0.1	0.1	0.3	-0.2	-0.6	-0.2
Cocaine response before conditioning	0.6	0.8	1.5	0.3	0.8	1.2
Saline control response	0.5	0.7	1.1	0.4	-1.0	-0.9
Condit. Reinf. active minus inactive responses	0.1	0.1	0.2	-0.2	-0.4	0.3
Condit. Reinf. active-inactive response ratio	0.2	0.2	0.6	-0.0	-0.8	0.1
Condit. Reinf. active responses	0.0	0.0	0.0	0.2	-0.0	0.2
Condit. Reinf. inactive responses	0.4	0.5	1.1	-0.1	1.1	0.6
Condit. Reinf. lever presses	0.9	1.2	2.2	0.1	-1.5	-1.2
Condit. Reinf. lever reinforcers received	0.0	0.1	0.1	0.4	0.0	0.2
Pavlov. Cond. lever latency	0.1	0.1	0.3	-0.2	0.5	0.1
Pavlov. Cond. magazine entry latency	0.2	0.2	0.5	0.7	0.3	0.3
Pavlov. Cond. change in total contacts	1.9	2.6	4.5	2.1	-1.3	-1.3
Pavlov. Cond. index score	0.4	0.5	1.1	1.0	-0.4	-0.4
Pavlov. Cond. latency score	0.2	0.3	0.8	0.9	-0.2	-0.3
Pavlov. Cond. lever contacts	0.5	0.6	1.3	0.4	-1.1	-0.7
Pavlov. Cond. magazine entry number	0.5	0.6	1.6	-1.3	-0.3	0.1
Pavlov. Cond. intertrial magazine entries	0.2	0.3	0.6	-0.1	-0.8	-0.6
Pavlov. Cond. lever-magazine prob. diff.	0.4	0.5	1.1	1.0	-0.4	-0.4
Pavlov. Cond. response bias	0.6	0.8	1.1	0.9	-1.0	-0.8
Conditioned reinforcement - actives	0.0	0.0	0.0	0.2	-0.2	0.1
Conditioned reinforcement - inactives	0.1	0.1	0.3	-0.5	-0.3	0.2
Conditioned locomotion	0.3	0.3	0.5	0.6	-0.7	-0.4
Intermittent access intake day 1-15 change	0.0	0.0	0.0	0.0	0.1	0.1
Intermittent access intake escalation	0.1	0.1	0.2	-0.4	0.1	0.4
Intermittent access intake escalation 2	0.2	0.2	0.4	-0.3	0.5	0.6
Intermitt. access day 1 inactive lever presses	4.1	4.4	9.3	-3.1	0.7	1.8
Intermitt. access day 15 inactive lever presses	0.5	0.6	1.1	-0.8	0.4	1.0
Intermitt. access escalation Index	1.3	1.2	1.4	-0.9	1.1	1.2
Intermittent access day 1 total infusions	0.8	0.9	1.9	1.4	-0.6	-0.7
Intermittent access day 15 total infusions	0.9	1.1	2.3	1.5	-0.6	-0.8
Intermittent access terminal intake (last 3 days)	1.7	1.8	4.1	2.0	-0.7	-1.0
Intermittent access total infusions	1.3	1.4	3.3	1.8	-0.7	-0.7
Intermittent access day 1 locomotion	0.6	0.6	0.8	0.7	-0.7	-0.9
Intermittent access day 15 total locomotion	0.2	0.3	0.4	0.7	-0.5	-0.2
Intermittent access total locomotion	0.5	0.5	0.8	0.9	-0.6	-0.6
Intermittent access standard deviation	0.4	0.4	1.2	1.1	0.0	-0.4
Cocaine induced anxiety	0.3	0.4	0.5	-0.7	0.3	0.7
Post-drug Anxiety	0.2	0.2	0.4	-0.3	0.6	0.5
Baseline Anxiety	0.1	0.1	0.4	0.1	0.6	0.1
Lifetime Intake	1.5	1.7	4.3	2.1	-0.4	-0.7
Incentive Sensitization - Responses	0.5	0.5	1.0	1.0	-0.5	-0.5
Incentive Sensitization - Breakpoint	0.4	0.4	0.8	0.9	-0.5	-0.4
Progressive ratio test 1 active lever presses	3.2	3.3	4.1	2.0	-1.4	-1.9
Progressive ratio test 1 breakpoint	3.4	3.5	4.9	2.2	-1.3	-1.9
Progressive ratio test 1 inactive lever presses	0.1	0.1	0.2	-0.5	-0.1	0.2
Progressive ratio test 2 active lever presses	1.3	1.4	3.2	1.8	-0.5	-0.8
Progressive ratio test 2 breakpoint	1.3	1.4	3.1	1.8	-0.6	-0.9
Progressive ratio test 2 inactive lever presses	0.1	0.1	0.2	0.4	-0.1	0.2
Total sessions with >9 infusions	1.8	1.9	4.4	2.1	-0.3	-1.1
Short access day 1 total inactive lever presses	0.6	0.7	1.0	-1.0	0.6	0.9
Short access day 10 total inactive lever presses	0.8	0.8	1.2	-1.1	0.6	1.0
Short access day 1 total infusions	1.9	2.0	5.0	2.2	-0.2	-1.0
Short access day 10 total infusions	3.0	3.3	3.7	1.9	-1.7	-1.8
Short access total infusions	3.2	3.6	7.2	2.7	-1.0	-1.6
Short access day 1 locomotion	2.4	2.5	3.1	1.7	-1.2	-1.8
Short access day 10 total locomotion	0.1	0.1	0.2	-0.4	0.4	0.0
Short access total locomotion	0.8	0.9	1.4	0.8	-0.7	-1.2
Compulsive drug intake	0.3	0.3	0.5	0.1	0.7	0.6
One hour access (0.3 mA shock)	1.2	1.4	4.2	2.1	0.2	0.1
One hour access (shock baseline)	0.6	0.7	1.9	1.4	-0.3	-0.3
Number of responses in last shaping day	0.2	0.2	0.5	0.7	0.2	-0.0
Context. condit. distance diff. score	0.4	0.5	1.1	1.1	-0.2	-0.5
Locomotion velocity, session 1	0.4	0.5	0.8	-0.4	0.9	0.6
Locomotion distance, session 1	0.2	0.2	0.4	0.6	0.5	-0.0
Locomotion velocity, session 2	0.2	0.2	0.3	-0.0	-0.6	-0.5
Locomotion distance, session 2	1.1	1.5	2.5	1.6	-0.7	-1.3
Locomotion velocity, session 3	0.6	0.7	1.7	1.3	-0.2	-0.6
Locomotion distance, session 3	1.3	1.4	2.6	1.6	-0.6	-1.1
Stereotopy head waving bouts, day 3	1.0	1.2	1.4	-1.2	1.0	1.1
Stereotopy head waving duration, day 3	0.3	0.4	0.6	-0.8	0.4	0.6
Locomotion velocity, session 7	1.4	1.5	2.2	1.5	-0.8	-1.3
Locomotion distance, session 7	0.4	0.5	0.8	0.9	-0.3	-0.7
Stereotopy head waving bouts, day 7	0.2	0.3	0.5	-0.5	-0.7	-0.3
Stereotopy head waving duration, day 7	0.2	0.3	0.6	-0.8	-0.4	0.0
Locomotion velocity, session 8	0.7	0.9	1.3	1.1	-0.9	-0.8
Locomotion distance, session 8	3.7	5.5	10.7	3.3	-1.3	-2.1
Degree of sensitization distance	0.3	0.3	0.7	-0.8	0.1	0.5
Degree of sensitization stereotypy	0.3	0.4	0.9	-1.0	-0.4	0.2
Condit. Reinf. active minus inactive responses	2.1	2.4	4.3	-0.7	1.5	2.1
Condit. Reinf. active-inactive response ratio	1.6	1.7	2.9	-1.0	1.1	1.7
Condit. Reinf. active responses	3.1	3.8	6.0	-1.4	1.8	2.4
Condit. Reinf. inactive responses	1.4	1.7	2.0	-1.4	1.1	1.4
Incentive salience index mean	0.7	0.9	1.8	0.2	0.9	1.3
Condit. Reinf. lever presses	0.3	0.4	1.2	1.1	-0.2	-0.1
Time in familiar zone, hab. session 1	0.1	0.1	0.1	0.3	-0.3	-0.3
Time in novel zone, hab. session 1	1.0	1.0	1.4	-1.2	0.7	1.0
Total zone transitions, hab. session 1	2.8	3.9	7.3	2.7	-1.5	-1.5
Total locomotion distance, hab. session 1	2.3	3.3	7.7	2.8	-1.1	-1.0
Locomotion velocity, hab. session 1	2.9	4.2	10.5	3.2	-1.0	-1.0
Time in familiar zone, hab. session 2	0.1	0.2	0.3	0.3	-0.5	-0.4
Time in novel zone, hab. session 2	0.7	0.7	0.9	-0.9	0.6	0.9
Total zone transitions, hab. session 2	0.6	0.7	2.2	1.5	0.1	-0.1
Total locomotion distance, hab. session 2	0.5	0.6	1.6	1.3	0.4	0.4
Locomotion velocity, hab. session 2	0.7	0.9	2.4	1.6	0.5	0.3
Novel to familiar place preference ratio	0.2	0.2	0.4	-0.3	-0.7	0.1
Novelty place preference	0.2	0.2	0.3	-0.5	-0.6	0.3
Time in novel zone, NPP test	0.2	0.2	0.5	-0.5	-0.7	0.1
Total zone transitions, NPP test	0.9	1.3	2.2	1.5	-0.8	-1.1
Total locomotion distance, NPP test	0.6	0.8	2.3	1.5	-0.1	-0.3
Locomotion velocity, NPP test	0.4	0.6	1.6	1.3	0.4	0.1
Pavlov. Cond. lever latency	0.4	0.6	0.8	0.5	-0.8	-0.9
Pavlov. Cond. magazine entry latency	0.4	0.5	1.1	0.1	0.6	1.0
Pavlov. Cond. change in total contacts	0.8	0.8	1.3	-0.4	1.0	1.1
Pavlov. Cond. index score	0.3	0.3	0.7	0.0	0.6	0.8
Pavlov. Cond. latency score	0.3	0.4	0.8	-0.0	0.7	0.9
Pavlov. Cond. lever contacts	0.0	0.0	0.1	0.3	0.1	0.2
Pavlov. Cond. magazine entry number	0.3	0.4	0.6	-0.3	-0.8	-0.7
Pavlov. Cond. intertrial magazine entries	0.0	0.1	0.1	-0.0	0.4	0.0
Pavlov. Cond. lever-magazine prob. diff.	0.1	0.2	0.3	0.2	0.3	0.6
Pavlov. Cond. response bias	0.2	0.3	0.4	0.3	0.6	0.6
Bone: apparent density	0.1	0.2	0.6	-0.1	-0.8	-0.3
Bone surface	0.2	0.3	0.5	0.3	-0.7	-0.5
Bone volume	0.6	1.1	1.9	0.6	-1.4	-1.0
Bone: connectivity density	0.4	0.7	1.6	-1.3	0.1	0.7
Bone: cortical apparent density	1.0	1.3	2.1	1.4	-0.4	-1.3
Bone: cortical area	1.6	2.4	3.1	1.4	-1.5	-1.8
Bone: cortical porosity	1.0	1.1	2.3	-0.3	-1.5	-0.9
Bone: cortical porosity	1.2	1.3	2.3	0.2	-1.5	-1.2
Bone: cortical thickness	1.3	2.1	3.3	0.9	-1.5	-1.8
Bone: cortical thickness	0.3	0.3	0.9	-0.9	-0.2	-0.3
Bone: cortical tissue density	1.0	1.3	2.1	1.5	-0.4	-1.2
Bone: elastic displacement	2.2	2.5	3.4	-1.8	1.3	1.5
Bone: elastic work	1.1	1.4	2.1	-1.5	0.9	1.1
Bone: endosteal estimation	0.0	0.1	0.1	0.0	0.3	0.3
Bone: endosteal perimeter	0.7	1.5	2.7	1.7	-0.6	-1.2
Bone: final force	0.6	0.9	1.3	0.4	-1.1	-1.1
Bone: final moment	0.5	0.9	1.2	0.4	-1.1	-1.1
Bone: marrow area	0.0	0.1	0.1	0.1	0.3	0.3
Bone: maximum diameter	1.2	2.2	3.0	1.7	-1.1	-1.5
Bone: maximum force	0.2	0.3	0.8	0.1	-0.9	-0.5
Bone: maximum moment	0.2	0.3	0.7	0.1	-0.8	-0.4
Bone: minimum diameter	3.1	5.8	7.6	2.8	-2.1	-2.3
Bone: periosteal estimation	0.4	0.9	1.4	1.2	-0.6	-0.9
Bone: periosteal perimeter	0.9	1.5	1.9	1.4	-1.0	-1.3
Bone: post-yield work	0.1	0.2	0.3	-0.6	-0.2	0.4
Bone: stiffness	2.7	4.3	5.7	1.4	-2.3	-2.4
Bone: tissue strength	0.4	0.4	0.6	-0.1	-0.8	-0.7
Bone: trabecular number	0.5	0.8	1.4	-1.2	0.5	0.9
Bone: trabecular spacing	0.2	0.3	0.6	0.1	0.5	0.8
Bone: trabecular thickness	1.4	1.7	2.4	0.8	-1.5	-1.5
Bone: trabecular tissue density	0.2	0.3	0.6	0.8	0.3	-0.5
Breakpoint value in progressive ratio session	0.5	0.5	0.9	-0.8	0.2	1.0
Distance traveled before self-admin	0.4	0.4	0.8	0.6	0.9	0.2
Distance traveled after self-admin	1.0	1.1	2.2	1.5	-0.1	-1.0
Delta time in closed arm before/after self-admin	0.1	0.1	0.1	0.2	-0.3	-0.4
Delta time in open arm before/after self-admin	0.6	0.6	0.9	-0.9	-0.9	-0.1
Diff in mean of infusions in LGA sessions	1.1	1.2	1.6	-1.3	1.1	0.9
Extinction: sum of active levers before priming	0.5	0.5	0.9	-0.5	0.6	0.9
Active lever presses in extinction session 6	0.6	0.6	0.9	0.7	-0.9	-0.7
Delta distance traveled before/after self-admin	0.7	0.8	1.3	0.7	-0.8	-1.1
Delta ambulatory time before/after self-admin	0.2	0.2	0.3	0.0	-0.5	-0.6
Time in closed arm before self-admin	0.2	0.2	0.5	0.7	-0.1	0.1
Time in closed arm after self-admin	0.5	0.5	0.6	0.7	-0.8	-0.6
Time in open arm before self-admin	0.6	0.6	1.2	-0.2	1.1	0.8
Time in open arm after self-admin	0.4	0.4	0.9	-1.0	-0.2	0.5
Sum of active levers in priming session hrs 5-6	0.3	0.3	0.6	0.4	-0.8	-0.2
Time to tail flick, vehicle, before self-admin	0.5	0.5	0.7	0.9	-0.8	-0.4
Time to tail flick, vehicle, after self-admin	0.5	0.5	1.2	-1.1	0.3	0.4
Time to tail flick, test, before self-admin	0.5	0.5	0.9	0.8	0.1	-0.9
Time to tail flick, test, after self-admin	0.1	0.1	0.2	0.5	0.4	0.2
Delta time to tail flick, vehicle, before/after SA	0.7	0.7	1.6	-1.3	0.5	0.4
Delta time to tail flick, test, before/after SA	0.3	0.3	0.7	-0.3	-0.1	0.9
Ambulatory time before self-admin	0.2	0.2	0.3	0.5	0.5	-0.1
Ambulatory time after self-admin	1.7	1.8	3.7	1.9	-0.2	-1.3
Total heroin consumption	0.0	0.1	0.1	0.1	0.2	0.4
Area under the delay curve	0.1	0.1	0.2	0.4	-0.5	-0.1
Delay disc. indifference point, 0s delay	0.2	0.3	0.7	-0.3	-0.8	0.0
Delay disc. indifference point, 16s delay	0.6	0.6	0.9	0.9	-0.6	-0.7
Delay disc. indifference point, 2s delay	0.3	0.3	0.8	0.9	-0.3	-0.1
Delay disc. indifference point, 24s delay	1.6	1.6	3.7	1.9	-0.6	-0.8
Delay disc. indifference point, 4s delay	0.1	0.1	0.2	-0.3	-0.4	-0.3
Delay disc. indifference point, 8s delay	0.3	0.3	0.7	-0.2	-0.8	-0.2
Delay discount exponential model param	0.2	0.2	0.3	-0.5	0.6	0.3
Delay discount hyperbolic model param	0.3	0.3	0.4	-0.5	0.6	0.4
Fecal boli incidents, locomotor time 1	1.7	1.8	2.9	0.5	-1.5	-1.7
Change in fecal boli incidents, locomotor task	2.7	2.5	3.9	-0.6	1.8	2.0
Time >=10cm from walls, locomotor time 1	0.5	0.5	0.9	-0.9	0.4	0.8
Bouts of movement, locomotor time 1	0.1	0.1	0.1	-0.4	-0.2	-0.1
Total resting periods, locomotor time 1	0.1	0.1	0.2	-0.5	0.1	0.2
Rest time, locomotor task time 1	0.5	0.5	1.1	-1.0	0.3	0.6
Distance moved, locomotor task time 1	0.1	0.1	0.2	0.5	-0.1	0.1
Vertical activity count, locomotor time 1	2.0	2.1	4.0	2.0	-0.7	-1.3
Time >=10cm from walls, locomotor time 2	1.0	1.1	2.0	-1.1	0.3	1.4
Bouts of movement, locomotor time 2	0.3	0.4	0.5	0.6	-0.5	-0.7
Total resting periods, locomotor time 2	0.2	0.3	0.3	0.6	-0.4	-0.5
Rest time, locomotor task time 2	0.4	0.5	0.8	-0.5	0.6	0.9
Distance moved, locomotor task time 2	0.1	0.2	0.3	0.0	-0.5	-0.4
Vertical activity count, locomotor time 2	5.9	6.4	8.3	1.7	-2.9	-2.9
Weight adjusted by age	0.8	0.9	2.0	1.4	-0.5	-0.6
Seeking ratio, delayed vs. immediate footshock	0.5	0.5	0.9	-0.2	-1.0	-0.8
Locomotion in novel chamber	0.7	0.9	2.4	1.6	-0.0	-0.4
Locomotion in novel chamber post-restriction	0.0	0.0	0.1	-0.0	-0.0	-0.2
Progressive ratio	3.4	4.0	5.7	-1.0	2.3	2.4
Food seeking constrained by brief footshock	0.6	0.7	1.1	0.7	-0.7	-1.1
Seeking ratio, punishment vs. effort	2.5	3.1	4.8	1.0	-1.9	-2.2
Run reversals in cocaine runway, females	1.7	1.7	3.5	1.9	0.2	-1.2
Run reversals in cocaine runway, males	0.3	0.3	0.4	-0.6	0.4	0.7
Latency to leave start box in cocaine runway	0.5	0.6	0.9	1.0	-0.6	-0.7
Latency to leave start box in cocaine runway, F	0.3	0.3	0.8	-0.1	0.9	0.5
Latency to leave start box in cocaine runway, M	4.5	4.3	5.7	1.7	-2.4	-2.1
Cd content in liver	2.3	2.5	3.4	1.3	-1.8	-1.6
Co content in liver	1.9	2.2	3.1	1.6	-1.0	-1.8
Cu content in liver	2.4	2.9	5.7	0.8	-1.5	-2.4
Fe content in liver	0.5	0.6	0.9	0.9	-0.6	-0.8
K content in liver	0.5	0.5	1.1	-0.4	-0.4	-1.1
Mg content in liver	0.1	0.1	0.2	-0.4	0.0	-0.3
Mn content in liver	0.2	0.2	0.5	0.2	-0.1	-0.7
Na content in liver	0.3	0.3	0.3	-0.6	-0.6	-0.5
Rb content in liver	0.5	0.6	1.7	-1.3	-0.2	-0.1
Se content in liver	0.3	0.3	0.8	0.9	0.3	-0.4
Sr content in liver	0.2	0.2	0.4	0.0	-0.7	-0.3
Zn content in liver	1.0	1.1	1.4	1.2	-0.8	-1.2