Hub : Genes

Hecw2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000013257 0.4 0.12 0.0e+00 0.18 0.21 0.2 0.2 6.4e-20 1.1e-22 2.7e-22 7.2e-22
2 Adipose intron excision ratio chr9:55488290:55492328 0.02 0.02 3.2e-03 0.01 0 0.01 0 5.6e-02 1.2e-01 6.7e-02 1.8e-01
3 Adipose mRNA stability ENSRNOG00000013257 0.04 0.04 6.9e-03 0.02 0.01 0.01 0.02 2.5e-03 2.3e-02 5.8e-02 2.5e-03
4 BLA mRNA stability ENSRNOG00000013257 0.22 0.09 4.0e-08 0.16 0.16 0.14 0.14 5.7e-09 7.6e-09 7.9e-08 5.1e-08
5 Brain gene expression ENSRNOG00000013257 0.14 0.07 1.1e-09 0.12 0.1 0.12 0.12 4.6e-11 6.8e-10 7.0e-11 6.1e-11
6 Brain intron excision ratio chr9:55408739:55424386 0.05 0.04 2.8e-03 0.02 0.02 0.02 0.02 5.2e-03 1.0e-02 5.1e-03 6.5e-03
7 Brain intron excision ratio chr9:55424495:55428967 0.05 0.04 2.8e-03 0.02 0.01 0.02 0.02 6.1e-03 1.3e-02 6.9e-03 7.9e-03
8 Brain mRNA stability ENSRNOG00000013257 0.32 0.11 0.0e+00 0.21 0.23 0.22 0.22 6.5e-19 5.7e-21 3.1e-20 2.3e-20
9 Liver gene expression ENSRNOG00000013257 0.2 0.09 4.8e-15 0.11 0.11 0.1 0.11 2.0e-12 2.8e-12 2.5e-11 3.2e-12
10 NAcc gene expression ENSRNOG00000013257 0.04 0.03 3.7e-03 0.03 0 0.01 0.01 5.1e-03 2.6e-01 1.1e-01 4.7e-02
11 NAcc mRNA stability ENSRNOG00000013257 0.14 0.08 1.4e-06 0.1 0.08 0.07 0.08 9.3e-08 2.2e-06 2.9e-06 7.8e-07
12 PL mRNA stability ENSRNOG00000013257 0.22 0.09 1.5e-10 0.16 0.14 0.06 0.15 4.4e-12 6.7e-11 2.4e-05 1.3e-11

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
BMI with tail0.93.012.41.5-3.10.9-1.11.31.8-0.6-0.51.33.5-1.1-1.1
BMI without tail0.20.41.1-0.9-0.30.50.9-0.20.2-0.11.0-0.90.10.90.9
Body weight0.62.38.6-1.62.6-1.21.2-0.6-1.60.80.5-1.0-2.91.11.1
Epididymis fat weight1.22.89.8-1.92.4-0.51.6-1.0-1.60.70.9-1.4-3.11.61.6
Glucose2.94.47.9-2.2-0.7-2.62.2-2.1-2.42.82.1-2.1-0.62.12.1
Heart weight0.60.81.81.00.5-0.7-1.30.5-0.00.2-1.11.20.1-1.3-1.3
Left kidney weight0.10.41.5-0.01.2-0.3-0.50.2-0.30.1-0.60.3-1.2-0.5-0.5
Right kidney weight0.20.72.10.11.5-1.2-0.7-0.2-0.70.6-0.90.5-1.0-0.6-0.6
Tail length4.714.349.1-4.05.9-1.83.2-2.5-3.71.42.0-3.3-7.03.23.2
Length with tail3.914.555.8-3.66.5-2.22.8-2.2-4.01.81.3-2.9-7.52.72.7
Length without tail0.40.83.7-0.31.8-1.00.1-0.3-1.00.6-0.4-0.2-1.90.10.1
Liver weight, left0.10.10.30.50.40.3-0.10.40.1-0.3-0.30.1-0.3-0.2-0.2
Liver weight, right0.10.10.60.20.80.70.00.10.1-0.3-0.20.1-0.6-0.0-0.0
Parametrial fat weight0.00.00.1-0.10.1-0.10.20.2-0.30.2-0.1-0.2-0.30.20.2
Retroperitoneal fat weight0.41.44.3-1.00.5-2.10.7-1.0-1.91.80.5-0.8-1.00.80.8
Intraocular pressure0.40.63.50.3-1.9-0.1-0.20.10.30.40.20.01.7-0.2-0.2
Extensor digitorum longus weight0.83.111.3-1.0-3.4-1.41.5-1.4-0.21.32.0-1.42.61.41.4
Soleus weight0.10.30.60.40.70.4-0.50.60.2-0.4-0.80.6-0.5-0.6-0.6
Tibialis anterior weight0.20.62.5-0.5-1.6-0.50.6-0.50.00.50.8-0.61.20.60.6
Tibia length2.05.618.1-2.43.6-1.51.9-1.9-2.71.41.1-1.9-4.31.91.9
Number of licking bursts0.30.40.60.7-0.20.4-0.80.80.6-0.4-0.80.80.3-0.8-0.8
Food consumed during 24 hour testing period0.60.72.3-0.70.3-1.50.4-0.5-1.51.50.2-0.4-0.60.40.4
Times rat made contact with spout0.81.01.9-1.20.0-1.30.8-0.9-1.41.30.7-0.9-0.60.90.9
Mean time between licks in bursts1.01.42.0-1.3-0.8-1.31.3-1.3-1.01.31.4-1.30.11.31.3
Mean num. licks in bursts0.70.81.2-1.00.1-1.00.9-0.9-1.11.00.9-0.9-0.50.90.9
Std. dev. time between licks in bursts0.20.31.6-0.2-1.30.00.3-0.30.4-0.00.5-0.31.00.30.3
Water consumed over 24 hours0.20.20.30.2-0.5-0.1-0.50.50.00.1-0.60.50.4-0.5-0.5
Indifference point 0 sec1.93.14.72.2-0.70.8-2.21.51.6-1.2-2.11.91.7-2.1-2.1
Indifference point AUC0.10.10.50.00.30.7-0.3-0.00.1-0.3-0.20.3-0.4-0.3-0.3
Indifference point function ln k1.41.93.31.6-0.91.2-1.21.81.7-1.6-1.21.21.5-1.3-1.3
Indifference point function log k1.41.93.31.6-0.91.2-1.21.81.7-1.6-1.21.21.5-1.3-1.3
Delay discounting total patch changes 0 sec1.82.84.62.1-0.70.7-2.21.51.3-0.9-2.11.81.7-2.1-2.1
Delay discounting total patch changes 12 sec0.81.02.91.20.10.1-1.40.30.00.3-1.71.20.5-1.4-1.4
Delay discounting total patch changes 18 sec1.31.84.21.3-1.50.9-1.50.91.5-0.8-0.91.32.0-1.4-1.4
Delay discounting total patch changes 24 sec0.10.10.20.3-0.40.1-0.30.5-0.10.4-0.40.10.5-0.3-0.3
Delay discounting total patch changes 6 sec1.11.72.71.5-1.11.5-1.40.41.4-1.0-1.31.11.7-1.3-1.3
Delay discounting time to switch 0 sec1.62.44.4-1.5-0.8-1.61.6-1.7-1.62.11.6-1.60.11.61.6
Delay discounting water rate 0 sec0.40.60.90.70.70.7-0.80.80.7-1.0-0.70.9-0.4-0.8-0.8
Delay discounting water rate 12 sec2.94.46.92.60.11.6-2.42.61.9-1.8-2.42.61.0-2.3-2.3
Delay discounting water rate 18 sec0.81.11.81.21.10.5-1.11.00.9-1.3-1.31.2-0.6-1.1-1.1
Delay discounting water rate 24 sec0.10.20.3-0.30.4-0.10.5-0.4-0.30.30.5-0.4-0.60.40.4
Delay discounting water rate 6 sec0.40.62.00.70.50.7-0.51.40.9-1.1-0.60.9-0.3-0.6-0.6
Locomotor activity0.10.10.30.30.50.2-0.3-0.00.5-0.5-0.20.30.0-0.2-0.2
Locomotor testing distance0.71.11.61.20.41.3-1.01.11.2-1.2-1.21.10.5-1.0-1.0
Locomotor testing rearing0.10.10.4-0.20.70.10.1-0.5-0.30.30.00.1-0.30.00.0
Light reinforcement 10.61.25.0-0.7-0.3-2.20.2-1.0-1.62.10.1-0.30.20.30.3
Light reinforcement 20.81.12.20.51.5-1.4-0.90.2-1.10.9-1.51.1-0.9-0.9-0.9
Reaction time number correct0.30.51.50.7-1.2-0.6-0.30.70.00.4-0.50.51.2-0.6-0.6
Reaction time mean minus median2.53.25.5-2.01.7-1.31.9-1.9-2.11.31.3-1.8-2.41.81.8
Reaction time mean minus median AUC1.21.63.4-1.41.4-1.11.2-1.2-1.61.10.8-1.1-1.81.11.1
Reaction time num false alarms1.01.43.9-0.7-2.0-1.20.6-1.9-0.61.30.8-0.91.60.80.8
Reaction time num false alarms AUC1.41.94.6-0.8-2.1-1.60.8-2.1-0.81.61.0-1.11.71.01.0
Reaction time trials correct on left0.30.51.50.7-1.2-0.6-0.30.70.00.4-0.50.51.2-0.6-0.6
Reaction time trials on left0.30.41.30.6-1.2-0.7-0.30.6-0.10.4-0.40.41.0-0.5-0.5
Reaction time mean2.73.78.4-2.02.5-1.81.6-1.5-2.51.81.2-1.6-2.91.61.6
Reaction time mean AUC3.14.27.9-2.22.4-2.11.7-1.5-2.72.01.4-1.7-2.81.71.7
Median of all reaction times2.02.76.7-1.62.3-1.61.2-1.0-2.11.61.0-1.2-2.61.21.2
Reaction time omissions1.52.04.1-1.41.3-1.51.2-1.3-2.01.60.7-1.2-1.71.31.3
Reaction time false alarm rate0.81.24.4-0.9-1.2-1.00.7-2.1-0.61.11.0-1.10.91.01.0
Reaction time premature initiation rate6.18.115.83.0-0.53.0-2.83.03.7-4.0-2.52.91.5-2.8-2.8
Reaction time premature initiations5.07.210.53.0-1.22.1-2.63.03.2-3.2-2.42.82.0-2.8-2.8
Std. dev. reaction times1.92.67.2-1.72.4-1.21.4-1.2-2.01.10.8-1.3-2.71.31.3
Reaction time trials completed0.30.41.30.6-1.2-0.7-0.30.6-0.10.4-0.40.41.0-0.5-0.5
Reaction time trials AUC0.30.41.50.5-1.2-0.8-0.10.5-0.20.6-0.30.31.1-0.4-0.4
Social response proportion1.01.16.40.12.5-0.6-0.40.4-0.80.1-0.80.5-2.1-0.4-0.4
Social responses0.60.82.9-0.71.6-1.10.3-0.6-1.10.50.3-0.5-1.70.50.5
Social time0.50.61.7-0.71.20.30.7-0.8-0.0-0.41.0-0.6-1.30.70.7
Conditioned locomotion0.91.05.7-0.52.4-0.10.0-0.0-0.90.1-0.40.0-2.3-0.0-0.0
Cocaine response after cond. corrected3.13.55.52.01.71.8-2.12.11.2-1.7-2.32.1-0.7-2.1-2.1
Cocaine response after cond. not corrected3.13.55.21.91.92.0-2.02.01.2-1.8-2.32.0-0.8-2.0-2.0
Cocaine response before conditioning0.20.20.4-0.4-0.30.20.5-0.50.3-0.20.6-0.50.20.50.5
Saline control response0.81.12.7-1.0-0.1-1.61.0-1.0-1.21.50.9-1.0-0.01.01.0
Condit. Reinf. active minus inactive responses2.43.07.01.62.61.6-1.71.70.7-1.5-2.11.7-1.6-1.7-1.7
Condit. Reinf. active-inactive response ratio3.13.25.31.81.42.3-1.81.91.5-2.1-2.01.8-0.7-1.8-1.8
Condit. Reinf. active responses2.12.95.41.82.21.2-1.91.90.6-1.1-2.31.9-1.0-1.9-1.9
Condit. Reinf. inactive responses0.30.30.60.70.3-0.7-0.60.5-0.30.6-0.80.60.4-0.6-0.6
Condit. Reinf. lever presses2.63.65.72.30.31.2-2.32.21.4-1.2-2.42.31.0-2.3-2.3
Condit. Reinf. lever reinforcers received2.73.76.92.12.11.3-2.22.20.8-1.3-2.62.2-0.8-2.2-2.2
Pavlov. Cond. lever latency1.92.63.5-1.80.3-1.31.9-1.8-1.51.31.8-1.9-1.21.91.9
Pavlov. Cond. magazine entry latency0.10.10.70.1-0.7-0.4-0.10.10.00.30.00.10.8-0.1-0.1
Pavlov. Cond. change in total contacts3.04.15.92.40.21.6-2.42.41.8-1.7-2.32.40.9-2.4-2.4
Pavlov. Cond. index score1.31.72.71.6-0.20.6-1.61.60.9-0.7-1.61.61.0-1.6-1.6
Pavlov. Cond. latency score1.01.32.01.3-0.10.4-1.41.40.7-0.5-1.41.40.8-1.4-1.4
Pavlov. Cond. lever contacts2.73.85.42.30.11.5-2.32.31.7-1.5-2.32.31.1-2.3-2.3
Pavlov. Cond. magazine entry number0.20.20.5-0.4-0.50.30.6-0.50.3-0.20.7-0.60.10.60.6
Pavlov. Cond. intertrial magazine entries0.00.00.10.2-0.20.2-0.20.20.10.0-0.40.20.1-0.2-0.2
Pavlov. Cond. lever-magazine prob. diff.1.51.92.81.6-0.30.8-1.71.61.1-0.9-1.61.71.1-1.7-1.7
Pavlov. Cond. response bias1.62.23.51.70.31.0-1.81.81.1-1.0-1.91.80.7-1.8-1.8
Conditioned reinforcement - actives1.21.23.5-1.1-0.3-1.40.8-1.9-1.21.41.1-0.8-0.20.80.8
Conditioned reinforcement - inactives0.40.41.5-0.40.1-1.20.2-1.2-0.91.20.2-0.2-0.20.20.2
Conditioned locomotion0.40.42.2-0.00.0-1.3-0.2-1.5-0.60.9-0.30.10.1-0.2-0.2
Intermittent access intake day 1-15 change0.30.31.0-0.4-0.4-0.80.4-0.8-0.71.00.4-0.50.20.40.4
Intermittent access intake escalation0.10.10.4-0.2-0.3-0.40.2-0.4-0.40.70.3-0.30.20.20.2
Intermittent access intake escalation 20.10.10.3-0.20.4-0.00.4-0.1-0.2-0.20.1-0.5-0.50.40.4
Intermitt. access day 1 inactive lever presses0.90.93.6-0.9-0.9-1.90.6-0.4-1.11.60.8-0.50.50.60.6
Intermitt. access day 15 inactive lever presses0.00.00.1-0.1-0.20.20.10.40.3-0.30.1-0.10.20.10.1
Intermitt. access escalation Index1.41.22.3-1.50.50.31.4-0.7-1.00.71.3-1.2-1.31.41.4
Intermittent access day 1 total infusions1.92.25.7-1.11.6-2.30.4-1.7-2.42.20.1-0.5-1.70.40.4
Intermittent access day 15 total infusions2.22.46.0-1.41.2-2.40.8-1.9-2.42.40.5-0.8-1.40.80.8
Intermittent access terminal intake (last 3 days)1.41.54.1-0.91.0-2.00.4-1.5-2.02.00.1-0.5-1.20.40.4
Intermittent access total infusions2.42.76.5-1.31.6-2.40.6-2.2-2.62.40.3-0.8-1.80.60.6
Intermittent access day 1 locomotion0.60.62.4-0.40.3-1.5-0.1-1.1-1.21.4-0.10.0-0.3-0.0-0.0
Intermittent access day 15 total locomotion0.90.92.6-0.51.2-1.60.1-1.1-1.51.4-0.4-0.3-1.10.10.1
Intermittent access total locomotion1.11.33.6-0.70.8-1.90.4-1.7-1.71.70.1-0.6-0.90.40.4
Intermittent access standard deviation0.91.03.5-0.90.5-1.90.8-0.7-1.31.20.3-1.0-0.80.80.8
Cocaine induced anxiety0.30.41.10.4-0.21.0-0.50.80.9-0.8-0.10.50.4-0.5-0.5
Post-drug Anxiety1.31.43.21.1-0.11.3-1.11.61.7-1.8-0.71.10.7-1.1-1.1
Baseline Anxiety0.10.10.40.20.20.0-0.10.10.3-0.6-0.20.1-0.1-0.1-0.1
Lifetime Intake2.42.76.4-1.41.1-2.40.8-2.2-2.52.50.6-0.9-1.40.80.8
Incentive Sensitization - Responses0.60.60.9-1.00.4-0.80.7-0.9-0.80.80.9-0.7-0.80.70.7
Incentive Sensitization - Breakpoint0.60.60.9-1.00.3-0.80.7-0.9-0.80.80.9-0.7-0.70.70.7
Progressive ratio test 1 active lever presses1.41.53.7-1.40.2-1.40.9-1.9-1.51.60.9-0.9-0.70.90.9
Progressive ratio test 1 breakpoint1.21.23.5-1.20.4-1.30.7-1.9-1.51.60.7-0.7-0.70.70.7
Progressive ratio test 1 inactive lever presses6.77.213.0-3.0-1.1-3.12.5-3.6-2.93.52.7-2.5-0.32.52.5
Progressive ratio test 2 active lever presses1.81.93.5-1.50.2-1.91.1-1.9-1.81.91.3-1.2-0.81.11.1
Progressive ratio test 2 breakpoint1.21.33.1-1.20.0-1.80.8-1.7-1.51.71.0-0.8-0.40.80.8
Progressive ratio test 2 inactive lever presses1.21.33.1-1.3-0.0-1.60.8-1.5-1.61.70.9-0.9-0.40.80.8
Total sessions with >9 infusions1.41.54.0-1.3-0.8-1.41.0-2.0-1.21.51.2-1.00.21.11.1
Short access day 1 total inactive lever presses0.91.02.50.21.0-1.6-0.6-1.3-1.31.5-1.00.5-0.5-0.6-0.6
Short access day 10 total inactive lever presses0.10.10.6-0.3-0.1-0.80.2-0.2-0.40.50.1-0.1-0.00.20.2
Short access day 1 total infusions0.91.02.3-0.90.5-1.40.6-1.5-1.41.50.4-0.5-0.80.60.6
Short access day 10 total infusions1.81.95.0-0.71.6-2.10.2-1.8-2.22.2-0.2-0.5-1.50.20.2
Short access total infusions1.21.33.8-0.90.5-1.70.4-1.7-1.81.90.3-0.6-0.70.50.5
Short access day 1 locomotion1.31.42.9-1.2-0.4-1.60.9-1.7-1.41.71.0-1.0-0.10.90.9
Short access day 10 total locomotion0.40.41.30.50.6-1.0-0.6-0.3-0.70.8-1.20.5-0.1-0.6-0.6
Short access total locomotion1.51.63.5-1.20.2-1.80.9-1.9-1.71.90.7-1.1-0.70.90.9
Compulsive drug intake0.20.20.90.2-0.50.90.10.50.7-0.6-0.00.10.40.10.1
One hour access (0.3 mA shock)1.21.43.7-0.51.5-1.90.2-1.3-1.91.9-0.4-0.1-1.40.20.2
One hour access (shock baseline)1.92.26.0-0.71.9-2.50.1-1.5-2.32.3-0.3-0.3-1.70.10.1
Number of responses in last shaping day2.12.13.7-1.7-1.5-1.21.6-1.0-1.21.51.9-1.50.41.61.6
Context. condit. distance diff. score0.80.92.1-0.7-1.5-0.60.9-1.20.00.51.2-0.91.10.90.9
Locomotion velocity, session 10.91.04.70.9-1.90.5-0.40.51.0-0.30.10.52.2-0.5-0.5
Locomotion distance, session 10.30.41.4-0.2-0.9-1.10.1-0.2-0.61.20.3-0.21.00.20.2
Locomotion velocity, session 20.81.04.40.9-2.00.0-0.70.50.8-0.1-0.30.72.1-0.7-0.7
Locomotion distance, session 20.20.31.3-0.2-0.7-0.90.1-0.2-0.81.10.3-0.10.50.10.1
Locomotion velocity, session 31.51.82.9-1.4-0.1-1.71.3-1.6-1.51.61.3-1.3-0.51.31.3
Locomotion distance, session 30.20.20.5-0.4-0.1-0.70.4-0.6-0.40.60.6-0.40.10.40.4
Stereotopy head waving bouts, day 30.81.02.4-0.8-1.5-0.61.0-0.9-0.20.61.4-1.00.81.01.0
Stereotopy head waving duration, day 31.01.22.0-1.1-1.0-1.01.2-1.2-0.81.01.4-1.20.21.21.2
Locomotion velocity, session 71.21.35.11.1-2.00.5-0.80.71.3-0.5-0.40.82.3-0.8-0.8
Locomotion distance, session 70.10.20.50.4-0.4-0.3-0.40.3-0.10.4-0.30.40.7-0.4-0.4
Stereotopy head waving bouts, day 70.00.00.10.3-0.1-0.1-0.20.20.1-0.0-0.10.20.2-0.2-0.2
Stereotopy head waving duration, day 70.10.10.3-0.0-0.5-0.30.3-0.30.00.20.4-0.30.50.30.3
Locomotion velocity, session 81.92.34.81.8-1.51.2-1.41.11.9-1.4-1.11.42.2-1.4-1.4
Locomotion distance, session 80.60.92.6-0.5-1.6-1.20.6-1.0-0.41.11.0-0.61.40.60.6
Degree of sensitization distance0.70.71.30.90.30.7-1.01.10.5-0.5-1.21.00.2-1.0-1.0
Degree of sensitization stereotypy0.40.40.90.90.10.2-0.80.70.4-0.3-0.80.80.3-0.8-0.8
Condit. Reinf. active minus inactive responses0.91.02.01.00.90.2-1.31.30.0-0.3-1.41.3-0.4-1.3-1.3
Condit. Reinf. active-inactive response ratio0.60.61.10.80.10.5-1.11.00.4-0.5-1.01.00.0-1.0-1.0
Condit. Reinf. active responses1.21.53.01.11.50.3-1.41.6-0.0-0.4-1.71.4-0.9-1.4-1.4
Condit. Reinf. inactive responses0.40.41.20.61.1-0.1-0.60.9-0.20.1-1.00.7-0.5-0.7-0.7
Incentive salience index mean1.82.24.21.51.10.7-1.81.90.4-0.8-2.11.8-0.5-1.8-1.8
Condit. Reinf. lever presses0.60.81.70.70.80.5-0.91.30.1-0.5-1.31.0-0.7-1.0-1.0
Time in familiar zone, hab. session 10.70.72.2-0.7-1.5-0.30.9-1.0-0.20.31.1-0.90.50.90.9
Time in novel zone, hab. session 10.70.61.50.91.20.5-0.91.00.3-0.4-0.90.9-0.4-0.9-0.9
Total zone transitions, hab. session 10.71.01.51.2-0.80.9-1.01.00.9-0.7-0.81.01.2-1.0-1.0
Total locomotion distance, hab. session 10.91.32.51.20.80.6-1.41.40.3-0.6-1.61.4-0.3-1.4-1.4
Locomotion velocity, hab. session 10.30.41.20.41.1-0.1-0.60.6-0.40.0-0.90.6-0.9-0.6-0.6
Time in familiar zone, hab. session 20.40.41.20.3-0.51.1-0.40.51.0-1.1-0.30.40.3-0.4-0.4
Time in novel zone, hab. session 20.50.51.3-0.30.6-1.20.4-0.6-1.01.20.4-0.4-0.30.40.4
Total zone transitions, hab. session 20.70.91.9-0.9-0.4-1.10.9-0.9-1.21.41.0-0.9-0.10.90.9
Total locomotion distance, hab. session 21.21.63.9-1.30.9-1.50.9-1.0-2.01.80.7-0.9-1.40.90.9
Locomotion velocity, hab. session 21.42.04.5-1.50.8-1.61.1-1.2-2.11.90.9-1.2-1.41.21.2
Novel to familiar place preference ratio1.61.76.1-0.62.2-1.60.0-0.1-2.01.4-0.5-0.0-2.50.00.0
Novelty place preference1.51.65.5-0.62.1-1.60.1-0.2-2.01.4-0.4-0.1-2.30.10.1
Time in novel zone, NPP test1.31.44.8-0.42.0-1.4-0.0-0.1-1.81.3-0.50.1-2.2-0.1-0.1
Total zone transitions, NPP test0.10.10.50.1-0.4-0.5-0.0-0.0-0.40.70.1-0.00.60.00.0
Total locomotion distance, NPP test0.20.20.40.30.7-0.3-0.50.5-0.50.4-0.60.5-0.4-0.5-0.5
Locomotion velocity, NPP test0.10.20.6-0.10.5-0.6-0.30.2-0.70.7-0.30.2-0.5-0.2-0.2
Pavlov. Cond. lever latency1.41.73.3-1.3-1.0-1.21.5-1.4-0.81.21.8-1.50.51.51.5
Pavlov. Cond. magazine entry latency1.92.43.51.60.91.8-1.71.71.4-1.8-1.91.7-0.4-1.7-1.7
Pavlov. Cond. change in total contacts3.23.46.12.00.61.4-2.22.21.2-1.4-2.52.30.2-2.3-2.3
Pavlov. Cond. index score1.31.73.01.21.11.3-1.41.40.8-1.3-1.71.4-0.7-1.4-1.4
Pavlov. Cond. latency score1.62.03.61.41.21.4-1.51.50.9-1.4-1.91.6-0.7-1.6-1.6
Pavlov. Cond. lever contacts1.11.32.91.01.10.9-1.31.30.5-0.9-1.71.3-0.7-1.3-1.3
Pavlov. Cond. magazine entry number1.31.62.9-1.2-1.1-1.11.4-1.4-0.71.21.7-1.40.81.41.4
Pavlov. Cond. intertrial magazine entries0.50.61.2-0.80.8-0.90.6-0.8-0.90.70.5-0.6-1.10.60.6
Pavlov. Cond. lever-magazine prob. diff.1.51.93.21.31.01.4-1.51.51.0-1.5-1.81.5-0.5-1.5-1.5
Pavlov. Cond. response bias0.81.01.80.81.10.9-1.01.10.5-1.0-1.41.1-0.9-1.1-1.1
Bone: apparent density1.01.78.1-0.12.9-0.5-0.50.4-1.30.5-1.40.5-2.6-0.5-0.5
Bone surface1.01.78.4-0.22.9-0.7-0.40.3-1.50.7-1.20.4-2.7-0.4-0.4
Bone volume1.22.19.60.13.1-0.3-0.80.7-1.30.4-1.70.8-2.8-0.8-0.8
Bone: connectivity density0.50.83.20.31.80.0-0.60.6-0.5-0.0-1.20.6-1.5-0.6-0.6
Bone: cortical apparent density0.91.26.70.6-2.4-0.4-0.50.40.40.7-0.20.52.6-0.5-0.5
Bone: cortical area0.10.10.4-0.10.1-0.60.0-0.0-0.60.5-0.10.0-0.5-0.0-0.0
Bone: cortical porosity1.51.65.4-1.22.1-0.51.1-1.0-1.20.40.7-1.0-2.31.01.0
Bone: cortical porosity1.81.97.6-1.22.7-0.51.0-0.9-1.30.30.4-1.0-2.81.01.0
Bone: cortical thickness0.20.42.40.3-1.6-0.1-0.10.10.50.00.10.21.2-0.2-0.2
Bone: cortical thickness1.92.23.21.8-1.31.1-1.61.51.5-1.0-1.31.61.7-1.6-1.6
Bone: cortical tissue density1.01.26.80.6-2.4-0.4-0.50.50.40.6-0.10.52.6-0.5-0.5
Bone: elastic displacement1.21.32.51.20.21.6-1.11.11.4-1.6-1.11.10.3-1.1-1.1
Bone: elastic work0.60.73.20.21.80.3-0.60.6-0.2-0.4-1.00.6-1.5-0.6-0.6
Bone: endosteal estimation1.02.211.2-0.53.3-0.7-0.20.1-1.70.7-0.90.2-3.2-0.2-0.2
Bone: endosteal perimeter0.61.37.1-0.42.6-0.2-0.0-0.0-1.10.2-0.60.0-2.7-0.0-0.0
Bone: final force1.83.06.4-1.81.6-2.11.3-1.4-2.51.90.8-1.3-2.51.31.3
Bone: final moment1.82.95.7-1.91.4-2.01.4-1.4-2.41.90.9-1.4-2.31.41.4
Bone: marrow area1.02.110.6-0.43.3-0.7-0.20.1-1.70.7-0.90.2-3.1-0.2-0.2
Bone: maximum diameter0.10.10.30.30.5-0.1-0.30.3-0.30.0-0.40.3-0.6-0.3-0.3
Bone: maximum force1.62.99.4-1.62.4-1.61.0-1.1-2.41.60.4-1.0-3.11.01.0
Bone: maximum moment1.62.78.4-1.72.1-1.71.1-1.1-2.31.60.5-1.1-2.91.11.1
Bone: minimum diameter0.20.42.1-0.31.2-0.3-0.10.0-0.80.4-0.40.1-1.5-0.1-0.1
Bone: periosteal estimation0.61.36.1-0.42.3-0.7-0.10.0-1.40.7-0.60.1-2.5-0.1-0.1
Bone: periosteal perimeter0.40.63.1-0.21.7-0.4-0.10.1-1.00.4-0.50.1-1.8-0.1-0.1
Bone: post-yield work1.31.73.8-1.41.3-1.41.0-1.0-1.91.60.6-1.0-1.91.01.0
Bone: stiffness2.74.37.9-2.22.0-2.31.8-1.8-2.82.21.2-1.8-2.81.81.8
Bone: tissue strength4.13.95.5-2.30.9-1.82.1-2.1-2.21.91.9-2.1-1.82.12.1
Bone: trabecular number0.50.83.7-0.41.9-0.5-0.10.0-1.00.4-0.70.1-1.9-0.1-0.1
Bone: trabecular spacing0.50.61.60.7-0.91.1-0.30.31.2-1.00.20.31.3-0.3-0.3
Bone: trabecular thickness0.50.61.50.41.2-0.1-0.70.7-0.40.1-1.20.8-1.0-0.8-0.8
Bone: trabecular tissue density0.91.32.1-1.3-0.2-1.31.1-1.1-1.31.51.1-1.1-0.31.11.1
Breakpoint value in progressive ratio session0.70.83.0-0.10.4-1.7-0.3-0.9-1.61.7-0.40.3-0.2-0.3-0.3
Distance traveled before self-admin0.50.63.20.21.8-0.4-0.3-0.2-0.5-0.1-0.70.3-1.5-0.3-0.3
Distance traveled after self-admin0.20.20.40.50.1-0.0-0.60.50.5-0.7-0.50.60.2-0.6-0.6
Delta time in closed arm before/after self-admin0.60.61.5-0.6-1.10.20.8-0.60.5-0.31.2-0.80.70.80.8
Delta time in open arm before/after self-admin1.51.45.60.72.41.0-0.80.9-0.1-0.7-1.30.9-1.8-0.8-0.8
Diff in mean of infusions in LGA sessions0.40.51.20.60.5-0.7-0.9-0.0-0.30.2-1.10.9-0.0-0.9-0.9
Extinction: sum of active levers before priming0.80.82.3-0.41.5-1.30.2-0.0-1.41.0-0.3-0.2-1.40.20.2
Active lever presses in extinction session 60.70.61.7-0.01.1-1.1-0.3-0.8-1.31.1-0.70.2-0.9-0.3-0.3
Delta distance traveled before/after self-admin0.10.10.7-0.1-0.8-0.3-0.00.40.20.00.10.10.8-0.0-0.0
Delta ambulatory time before/after self-admin0.10.10.3-0.3-0.2-0.60.20.2-0.40.50.1-0.10.20.20.2
Time in closed arm before self-admin1.11.37.00.22.60.8-0.30.7-0.1-0.7-0.90.3-2.3-0.3-0.3
Time in closed arm after self-admin1.31.32.51.20.91.6-1.01.31.3-1.6-1.11.0-0.3-1.0-1.0
Time in open arm before self-admin2.32.45.7-1.3-2.4-1.71.4-1.6-0.71.41.8-1.41.61.41.4
Time in open arm after self-admin0.20.20.6-0.30.8-0.30.1-0.1-0.70.4-0.00.0-0.80.10.1
Sum of active levers in priming session hrs 5-60.90.92.7-0.31.2-1.4-0.1-1.2-1.61.5-0.30.0-1.0-0.1-0.1
Time to tail flick, vehicle, before self-admin0.80.81.7-0.8-1.10.71.10.10.5-0.41.3-1.00.41.11.1
Time to tail flick, vehicle, after self-admin0.10.10.2-0.4-0.20.10.3-0.10.1-0.20.5-0.30.00.30.3
Time to tail flick, test, before self-admin0.10.10.30.3-0.6-0.4-0.2-0.1-0.00.2-0.20.30.6-0.2-0.2
Time to tail flick, test, after self-admin0.50.51.2-0.9-0.9-0.30.90.30.1-0.01.1-0.90.40.90.9
Delta time to tail flick, vehicle, before/after SA0.30.31.1-0.20.6-1.0-0.2-1.0-0.80.7-0.30.1-0.4-0.2-0.2
Delta time to tail flick, test, before/after SA0.20.20.3-0.3-0.40.50.30.50.5-0.50.5-0.30.30.30.3
Ambulatory time before self-admin0.20.21.20.21.1-0.40.1-0.2-0.30.1-0.50.1-1.0-0.1-0.1
Ambulatory time after self-admin0.20.20.50.5-0.1-0.6-0.60.20.00.1-0.70.60.4-0.6-0.6
Total heroin consumption0.70.93.5-0.40.3-1.80.2-0.6-1.61.90.0-0.1-0.30.10.1
Area under the delay curve0.50.51.00.8-0.40.8-0.61.00.9-0.8-0.50.30.8-0.6-0.6
Delay disc. indifference point, 0s delay0.50.62.90.7-1.3-0.5-0.60.00.10.6-0.30.31.7-0.6-0.6
Delay disc. indifference point, 16s delay0.40.40.60.7-0.10.8-0.60.60.7-0.7-0.60.50.6-0.6-0.6
Delay disc. indifference point, 2s delay1.71.92.91.7-0.51.0-1.71.41.1-0.9-1.61.51.3-1.7-1.7
Delay disc. indifference point, 24s delay0.20.20.4-0.3-0.60.10.4-0.00.2-0.10.6-0.70.60.40.4
Delay disc. indifference point, 4s delay0.50.62.20.8-1.00.6-0.50.71.0-0.6-0.30.21.5-0.5-0.5
Delay disc. indifference point, 8s delay0.20.20.70.1-0.00.9-0.00.70.7-0.80.0-0.20.0-0.0-0.0
Delay discount exponential model param0.50.51.1-0.80.3-0.80.6-1.1-0.90.80.6-0.3-0.70.70.7
Delay discount hyperbolic model param0.60.71.4-0.90.5-0.90.7-1.2-1.10.90.6-0.4-1.00.70.7
Fecal boli incidents, locomotor time 11.61.82.91.31.51.6-1.21.71.0-1.4-1.51.4-0.5-1.2-1.2
Change in fecal boli incidents, locomotor task0.10.10.3-0.1-0.30.30.3-0.50.4-0.40.5-0.40.00.30.3
Time >=10cm from walls, locomotor time 15.55.58.52.7-0.32.9-2.42.42.7-2.8-2.12.21.5-2.4-2.4
Bouts of movement, locomotor time 10.50.61.00.80.51.0-0.80.60.9-1.0-0.90.40.0-0.8-0.8
Total resting periods, locomotor time 10.91.01.41.1-0.21.1-1.10.91.2-1.1-1.00.70.8-1.1-1.1
Rest time, locomotor task time 10.40.51.7-0.6-0.3-1.20.2-0.4-1.21.30.2-0.30.00.20.2
Distance moved, locomotor task time 11.01.13.01.10.21.6-0.80.81.5-1.7-0.71.10.3-0.8-0.8
Vertical activity count, locomotor time 10.40.51.0-0.2-0.90.60.7-0.10.9-0.71.0-0.60.70.70.7
Time >=10cm from walls, locomotor time 23.13.36.22.10.91.5-2.31.30.9-1.4-2.52.30.0-2.3-2.3
Bouts of movement, locomotor time 21.71.82.91.6-0.50.6-1.61.70.9-0.6-1.61.51.5-1.6-1.6
Total resting periods, locomotor time 21.81.92.81.6-0.50.6-1.71.70.9-0.5-1.71.61.4-1.6-1.6
Rest time, locomotor task time 20.40.51.1-0.8-0.6-0.40.8-0.5-0.40.40.9-1.10.20.80.8
Distance moved, locomotor task time 21.21.42.61.30.51.2-1.30.91.1-1.3-1.31.60.1-1.3-1.3
Vertical activity count, locomotor time 20.20.20.50.5-0.4-0.2-0.50.30.20.2-0.40.70.7-0.5-0.5
Weight adjusted by age0.60.72.00.61.01.4-0.5-0.80.8-1.3-0.70.4-0.7-0.4-0.4
Seeking ratio, delayed vs. immediate footshock0.40.53.10.21.8-0.3-0.20.1-0.50.1-0.30.1-1.3-0.2-0.2
Locomotion in novel chamber0.20.31.00.5-0.80.0-0.50.10.4-0.1-0.40.51.0-0.5-0.5
Locomotion in novel chamber post-restriction0.40.52.6-0.0-1.60.60.20.60.7-0.60.5-0.21.20.20.2
Progressive ratio0.60.72.4-0.8-1.5-0.20.8-1.1-0.10.41.0-0.80.70.80.8
Food seeking constrained by brief footshock0.40.51.7-0.3-0.01.30.5-0.51.0-1.20.7-0.5-0.30.50.5
Seeking ratio, punishment vs. effort0.40.51.80.21.40.9-0.00.70.6-0.9-0.20.1-1.0-0.0-0.0
Run reversals in cocaine runway, females0.40.41.1-0.7-0.9-0.20.7-0.00.2-0.21.0-0.70.40.70.7
Run reversals in cocaine runway, males1.61.52.61.40.20.9-1.41.21.1-1.2-1.61.50.4-1.4-1.4
Latency to leave start box in cocaine runway1.21.37.60.4-2.8-0.3-0.20.30.50.40.30.22.6-0.2-0.2
Latency to leave start box in cocaine runway, F1.11.27.80.0-2.8-0.10.2-0.30.60.20.9-0.22.30.20.2
Latency to leave start box in cocaine runway, M0.60.61.50.7-1.0-0.1-0.71.20.30.2-0.70.71.2-0.7-0.7
Cd content in liver2.22.43.1-1.80.1-1.71.7-1.7-1.71.71.6-1.7-0.81.71.7
Co content in liver0.50.51.4-0.6-1.2-0.40.8-0.7-0.10.41.0-0.80.60.80.8
Cu content in liver0.30.30.60.30.80.4-0.60.60.1-0.4-0.80.6-0.5-0.6-0.6
Fe content in liver0.70.84.5-0.32.1-0.3-0.10.1-1.00.3-0.60.1-2.0-0.1-0.1
K content in liver0.20.20.70.20.00.8-0.30.30.7-0.8-0.20.3-0.1-0.3-0.3
Mg content in liver0.20.20.50.20.70.7-0.30.30.4-0.7-0.40.3-0.4-0.3-0.3
Mn content in liver0.50.61.70.2-1.31.0-0.00.11.3-1.00.20.01.3-0.0-0.0
Na content in liver0.80.91.81.10.40.8-1.11.10.6-0.8-1.31.1-0.1-1.1-1.1
Rb content in liver1.72.13.21.80.31.5-1.61.61.5-1.5-1.71.60.6-1.6-1.6
Se content in liver0.10.10.60.20.80.0-0.30.3-0.2-0.0-0.50.3-0.5-0.3-0.3
Sr content in liver4.13.75.7-2.4-0.0-2.02.0-2.0-2.22.02.0-2.0-1.52.02.0
Zn content in liver0.20.20.5-0.70.2-0.40.5-0.5-0.50.40.4-0.5-0.40.50.5