Hub : Genes

Cradd

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative polyA ENSRNOT00000063946 0.18 0.06 1.1e-11 0.1 0.08 0.09 0.1 2.4e-11 1.5e-09 1.6e-10 5.7e-11
2 Adipose alternative polyA ENSRNOT00000105619 0.18 0.06 1.5e-11 0.09 0.08 0.09 0.1 4.5e-10 1.7e-09 1.8e-10 6.2e-11
3 Adipose gene expression ENSRNOG00000008507 0.06 0.03 2.3e-04 0.04 0.03 0.03 0.04 5.8e-05 3.6e-04 2.3e-04 5.8e-05
4 Adipose isoform ratio ENSRNOT00000063946 0.15 0.06 1.8e-10 0.1 0.07 0.09 0.09 9.5e-11 2.9e-08 5.9e-10 1.7e-10
5 Adipose isoform ratio ENSRNOT00000105619 0.15 0.06 2.3e-10 0.1 0.07 0.09 0.09 1.2e-10 4.0e-08 7.4e-10 2.0e-10
6 BLA gene expression ENSRNOG00000008507 0.15 0.08 1.4e-03 0.01 0.04 0.07 0.03 7.3e-02 2.2e-03 9.0e-05 1.4e-02
7 Brain intron excision ratio chr7:29937319:29938544 0.1 0.04 6.2e-06 0.06 0.05 0.05 0.05 3.7e-06 1.8e-05 1.2e-05 9.8e-06
8 Liver gene expression ENSRNOG00000008507 0.52 0.08 0.0e+00 0.31 0.31 0.32 0.32 5.0e-35 1.9e-35 7.0e-37 8.6e-37
9 Liver intron excision ratio chr7:29937319:29938544 0.11 0.05 1.8e-06 0.05 0.05 0.04 0.04 7.7e-06 2.3e-06 2.2e-05 1.2e-05
10 Liver mRNA stability ENSRNOG00000008507 0.14 0.05 9.6e-10 0.05 0.07 0.07 0.07 1.5e-06 2.8e-08 2.3e-08 3.9e-08
11 NAcc intron excision ratio chr7:29938663:29951394 0.28 0.16 2.9e-03 -0 0.02 0.03 0.01 3.9e-01 9.0e-03 3.6e-03 9.0e-02
12 PL gene expression ENSRNOG00000008507 0.18 0.08 1.2e-06 0.1 0.07 0.08 0.08 3.5e-08 3.4e-06 9.1e-07 1.6e-06
13 PL mRNA stability ENSRNOG00000008507 0.09 0.05 1.7e-05 0.07 0.07 0.07 0.07 2.3e-06 2.8e-06 4.3e-06 5.1e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
BMI with tail3.912.723.53.9-3.9-3.93.9-3.92.03.3-4.82.9-3.1-2.43.83.4
BMI without tail1.83.716.51.7-1.7-1.71.7-1.70.21.4-2.51.5-0.5-1.91.74.1
Body weight4.016.8105.33.4-3.4-3.43.4-3.4-0.73.5-4.01.90.1-3.43.410.3
Epididymis fat weight1.43.26.51.6-1.6-1.71.6-1.62.51.8-1.30.8-0.9-2.51.62.5
Glucose0.00.10.20.1-0.1-0.10.1-0.10.40.1-0.20.5-0.40.30.20.4
Heart weight1.11.63.11.4-1.4-1.41.4-1.4-1.80.9-1.20.3-0.80.91.41.3
Left kidney weight0.72.114.01.2-1.2-1.21.2-1.2-0.01.2-1.10.60.3-1.41.33.7
Right kidney weight0.51.310.90.5-0.5-0.60.5-0.5-0.30.6-0.60.00.6-1.70.63.3
Tail length2.16.344.2-1.21.31.3-1.21.2-2.6-0.51.6-1.14.0-1.4-1.26.6
Length with tail2.69.493.80.2-0.1-0.10.2-0.2-2.70.90.2-0.83.7-2.20.29.7
Length without tail2.14.534.11.6-1.6-1.61.6-1.6-1.41.8-1.50.10.8-1.01.65.8
Liver weight, left0.81.23.31.0-1.0-1.01.0-1.01.21.3-0.71.0-1.2-1.81.10.9
Liver weight, right0.40.76.00.1-0.10.00.1-0.10.40.60.2-0.20.4-2.50.11.4
Parametrial fat weight0.20.41.10.7-0.7-0.60.7-0.7-0.10.6-0.30.1-0.90.00.7-1.0
Retroperitoneal fat weight1.13.512.11.6-1.5-1.61.6-1.61.71.3-1.31.1-0.7-3.21.63.5
Intraocular pressure0.20.22.0-0.20.20.2-0.20.20.5-0.10.30.2-0.4-0.2-0.2-1.4
Extensor digitorum longus weight0.00.21.10.1-0.2-0.20.1-0.1-1.00.0-0.10.20.10.30.21.0
Soleus weight0.30.82.31.0-1.0-1.01.0-1.0-0.50.9-0.50.5-0.61.51.0-0.2
Tibialis anterior weight0.20.81.70.9-0.9-0.90.9-0.9-0.61.3-0.90.6-1.11.10.90.5
Tibia length2.77.741.92.4-2.4-2.42.4-2.4-0.22.6-2.91.6-0.2-2.12.46.5
Number of licking bursts1.21.42.11.2-1.2-1.21.2-1.21.41.1-1.41.5-1.10.31.30.4
Food consumed during 24 hour testing period0.20.21.5-0.20.20.2-0.20.2-0.0-0.6-0.7-0.30.30.2-0.21.2
Times rat made contact with spout2.52.95.21.7-1.7-1.71.7-1.70.91.9-2.12.3-1.11.51.81.1
Mean time between licks in bursts1.62.32.91.7-1.7-1.71.7-1.70.81.5-1.61.4-1.6-1.11.71.2
Mean num. licks in bursts0.10.10.60.0-0.0-0.00.0-0.0-0.50.3-0.10.10.00.70.0-0.3
Std. dev. time between licks in bursts1.61.93.41.6-1.6-1.61.6-1.61.01.6-0.90.9-1.8-1.11.6-0.1
Water consumed over 24 hours0.40.52.5-0.0-0.00.0-0.00.0-0.8-0.2-0.80.20.61.60.11.3
Indifference point 0 sec0.30.52.0-0.50.50.6-0.50.5-1.4-0.60.5-1.01.10.3-0.40.4
Indifference point AUC0.30.30.9-0.60.60.5-0.60.6-0.2-0.51.0-0.20.9-0.4-0.50.4
Indifference point function ln k0.20.31.10.5-0.5-0.40.5-0.5-0.3-0.1-1.00.1-0.50.90.4-0.1
Indifference point function log k0.20.31.10.5-0.5-0.40.5-0.5-0.3-0.1-1.00.1-0.50.90.4-0.1
Delay discounting total patch changes 0 sec0.30.41.9-0.40.40.5-0.40.4-1.4-0.60.4-1.01.10.1-0.30.4
Delay discounting total patch changes 12 sec0.60.81.20.9-1.0-1.00.9-0.90.81.0-0.60.9-0.3-1.11.10.8
Delay discounting total patch changes 18 sec0.30.41.3-0.50.50.5-0.50.50.2-0.40.9-0.41.1-0.6-0.31.0
Delay discounting total patch changes 24 sec0.20.21.5-0.00.0-0.1-0.00.0-0.50.10.0-0.10.7-0.80.11.2
Delay discounting total patch changes 6 sec0.00.00.1-0.0-0.00.0-0.00.00.2-0.0-0.10.10.1-0.20.2-0.4
Delay discounting time to switch 0 sec0.10.20.9-0.30.40.2-0.30.31.00.10.4-0.20.3-0.6-0.4-0.8
Delay discounting water rate 0 sec3.45.38.02.7-2.7-2.62.7-2.70.12.4-2.51.9-1.7-0.92.82.3
Delay discounting water rate 12 sec0.30.41.50.5-0.6-0.50.5-0.50.10.3-1.00.90.00.10.61.2
Delay discounting water rate 18 sec0.50.61.10.8-0.9-0.80.8-0.80.50.5-1.00.9-0.8-0.90.90.6
Delay discounting water rate 24 sec2.43.39.71.9-1.9-1.91.9-1.90.21.9-2.11.3-0.8-1.11.93.1
Delay discounting water rate 6 sec3.34.89.62.3-2.3-2.22.3-2.31.32.0-2.32.1-1.1-2.42.33.1
Locomotor activity3.75.911.02.7-2.6-2.82.7-2.70.62.7-2.62.0-1.3-1.52.73.3
Locomotor testing distance4.57.410.23.1-3.1-3.23.1-3.11.43.1-3.12.7-2.4-0.83.02.1
Locomotor testing rearing1.62.53.41.8-1.7-1.81.8-1.80.31.7-1.81.8-1.3-0.41.51.8
Light reinforcement 10.10.32.50.1-0.1-0.20.1-0.11.6-0.2-0.40.4-0.3-0.50.10.1
Light reinforcement 20.70.91.4-1.11.11.0-1.11.1-0.2-1.20.7-1.10.80.4-1.0-0.8
Reaction time number correct0.30.41.40.7-0.6-0.60.7-0.70.20.4-0.51.1-0.61.20.6-0.2
Reaction time mean minus median0.70.91.8-1.01.01.0-1.01.0-1.3-0.51.3-1.20.5-0.2-1.1-0.8
Reaction time mean minus median AUC0.20.30.5-0.50.50.5-0.50.5-0.6-0.20.7-0.70.1-0.4-0.6-0.7
Reaction time num false alarms1.01.32.1-1.11.11.0-1.11.1-1.4-1.40.8-1.00.91.4-1.1-1.2
Reaction time num false alarms AUC0.81.11.8-1.00.90.9-1.01.0-1.3-1.20.8-0.80.61.4-1.0-1.2
Reaction time trials correct on left0.30.41.40.7-0.6-0.60.7-0.70.20.4-0.51.1-0.61.20.6-0.2
Reaction time trials on left0.30.51.60.6-0.6-0.60.6-0.60.10.4-0.51.1-0.61.30.6-0.3
Reaction time mean0.50.71.11.1-1.0-1.01.1-1.10.00.8-0.70.6-1.0-0.80.90.7
Reaction time mean AUC0.40.50.80.9-0.8-0.80.9-0.9-0.30.7-0.50.4-0.7-0.90.70.8
Median of all reaction times1.41.92.61.6-1.6-1.61.6-1.60.41.2-1.41.1-1.2-1.21.51.4
Reaction time omissions0.91.39.6-0.50.40.4-0.50.50.1-0.40.3-0.2-1.02.0-0.6-3.1
Reaction time false alarm rate1.01.41.9-1.31.31.2-1.31.3-1.2-1.31.1-1.40.90.5-1.3-1.2
Reaction time premature initiation rate1.11.56.30.9-0.9-0.90.9-0.92.51.2-0.31.4-1.3-1.81.0-0.2
Reaction time premature initiations0.91.34.91.0-0.9-1.01.0-1.02.21.1-0.51.7-1.2-1.11.0-0.2
Std. dev. reaction times0.30.41.0-0.50.50.6-0.50.5-1.0-0.40.9-0.7-0.00.1-0.6-1.0
Reaction time trials completed0.30.51.60.6-0.6-0.60.6-0.60.10.4-0.51.1-0.61.30.6-0.3
Reaction time trials AUC0.30.51.40.7-0.7-0.60.7-0.70.30.5-0.51.2-0.61.00.6-0.2
Social response proportion0.80.82.21.1-1.1-0.91.1-1.1-0.31.5-0.50.7-0.40.21.20.6
Social responses2.53.25.62.1-2.0-2.02.1-2.10.92.4-1.52.0-1.6-0.92.00.6
Social time0.50.61.70.8-0.8-0.80.8-0.80.70.9-0.61.3-0.40.70.70.2
Conditioned locomotion0.80.91.3-1.11.11.1-1.11.1-1.0-1.10.7-1.11.00.2-1.1-0.1
Cocaine response after cond. corrected0.60.74.10.2-0.3-0.20.2-0.2-2.0-0.2-0.80.40.11.80.20.5
Cocaine response after cond. not corrected0.70.83.50.5-0.5-0.50.5-0.5-1.90.2-1.10.7-0.21.80.50.5
Cocaine response before conditioning0.30.40.90.6-0.5-0.60.6-0.60.90.9-0.60.7-0.8-0.30.6-0.5
Saline control response0.20.21.5-0.20.20.2-0.20.2-0.10.20.2-0.10.6-0.7-0.21.2
Condit. Reinf. active minus inactive responses0.91.16.80.5-0.5-0.50.5-0.51.81.10.00.1-1.2-2.60.5-0.2
Condit. Reinf. active-inactive response ratio0.20.21.6-0.10.10.1-0.10.10.70.30.4-0.1-0.4-1.3-0.00.5
Condit. Reinf. active responses1.01.45.60.9-0.9-0.90.9-0.92.01.2-0.60.3-1.5-2.40.9-0.5
Condit. Reinf. inactive responses0.60.72.30.8-0.8-0.80.8-0.80.90.6-1.00.2-1.2-0.50.8-1.5
Condit. Reinf. lever presses1.01.311.1-0.10.10.1-0.10.12.20.20.8-0.2-0.4-3.3-0.10.4
Condit. Reinf. lever reinforcers received1.21.76.60.9-0.9-0.90.9-0.92.31.3-0.60.2-1.5-2.61.0-0.6
Pavlov. Cond. lever latency0.81.16.4-0.50.50.5-0.50.5-2.5-0.9-0.50.01.02.2-0.6-0.0
Pavlov. Cond. magazine entry latency0.60.73.10.7-0.7-0.70.7-0.71.80.7-0.80.7-0.8-0.80.60.0
Pavlov. Cond. change in total contacts2.02.86.51.5-1.5-1.51.5-1.52.51.9-0.70.7-1.2-2.51.51.9
Pavlov. Cond. index score1.21.57.31.0-0.9-1.01.0-1.02.71.2-0.40.6-1.0-2.00.90.6
Pavlov. Cond. latency score0.91.16.30.6-0.6-0.60.6-0.62.50.9-0.10.3-0.8-2.10.60.5
Pavlov. Cond. lever contacts2.12.99.91.6-1.6-1.61.6-1.63.21.8-0.40.8-1.8-2.31.60.4
Pavlov. Cond. magazine entry number2.22.78.8-1.61.51.6-1.61.6-3.0-1.71.3-1.41.61.6-1.5-0.6
Pavlov. Cond. intertrial magazine entries0.10.11.00.0-0.1-0.00.0-0.0-1.0-0.2-0.6-0.1-0.2-0.10.10.0
Pavlov. Cond. lever-magazine prob. diff.1.11.46.60.9-0.9-0.90.9-0.92.61.1-0.30.6-0.9-1.80.90.7
Pavlov. Cond. response bias2.63.610.11.9-1.9-1.91.9-1.93.22.1-0.91.2-2.0-1.81.90.7
Conditioned reinforcement - actives0.60.63.40.4-0.3-0.50.4-0.40.10.4-0.50.60.1-1.80.21.8
Conditioned reinforcement - inactives0.40.53.5-0.10.20.2-0.10.1-0.9-0.10.50.20.9-0.7-0.21.9
Conditioned locomotion0.30.43.0-0.20.30.2-0.20.2-0.6-0.20.1-0.21.0-0.7-0.31.7
Intermittent access intake day 1-15 change2.02.03.81.3-1.3-1.31.3-1.32.01.3-1.31.7-0.8-1.61.31.7
Intermittent access intake escalation2.62.55.11.5-1.5-1.61.5-1.52.21.5-1.52.0-1.1-1.21.51.7
Intermittent access intake escalation 20.90.92.21.0-0.9-1.11.0-1.01.50.7-0.91.1-0.5-0.80.91.1
Intermitt. access day 1 inactive lever presses0.91.02.7-0.91.01.0-0.90.9-0.9-1.20.9-1.10.4-0.0-1.0-1.6
Intermitt. access day 15 inactive lever presses0.30.42.1-0.30.40.5-0.30.3-1.4-0.70.5-1.00.3-0.4-0.40.2
Intermitt. access escalation Index0.40.31.7-0.20.20.2-0.20.20.7-0.30.2-0.0-0.6-1.1-0.2-1.3
Intermittent access day 1 total infusions0.50.54.6-0.30.30.3-0.30.3-0.5-0.4-0.1-0.21.0-0.4-0.42.2
Intermittent access day 15 total infusions0.91.08.10.5-0.4-0.40.5-0.50.50.4-0.80.80.7-1.20.42.8
Intermittent access terminal intake (last 3 days)1.31.49.90.8-0.8-0.70.8-0.80.20.7-1.10.60.4-1.70.73.2
Intermittent access total infusions1.21.410.60.8-0.7-0.70.8-0.8-0.00.7-1.20.50.5-1.30.73.3
Intermittent access day 1 locomotion1.81.84.6-1.21.31.4-1.21.2-1.7-1.11.1-1.32.10.6-1.31.6
Intermittent access day 15 total locomotion2.42.67.4-1.41.51.4-1.41.4-1.5-1.41.0-1.22.70.7-1.52.5
Intermittent access total locomotion1.82.16.7-1.21.31.3-1.21.2-1.3-1.20.7-1.32.4-0.1-1.32.6
Intermittent access standard deviation1.31.44.61.1-1.0-1.21.1-1.11.01.0-1.21.4-0.1-0.71.02.2
Cocaine induced anxiety0.80.93.2-0.90.90.7-0.90.9-0.8-1.10.5-1.00.11.8-0.9-0.9
Post-drug Anxiety0.70.82.9-0.80.80.7-0.80.8-0.7-1.10.5-1.0-0.01.2-0.8-1.7
Baseline Anxiety0.10.10.60.1-0.10.10.1-0.1-0.10.1-0.1-0.00.2-0.80.1-0.1
Lifetime Intake1.21.39.30.9-0.8-0.80.9-0.90.00.8-1.30.50.2-1.20.83.1
Incentive Sensitization - Responses0.50.52.40.4-0.4-0.40.4-0.40.20.2-0.51.00.4-1.10.41.5
Incentive Sensitization - Breakpoint0.30.31.70.3-0.3-0.20.3-0.30.20.0-0.30.80.5-0.90.21.3
Progressive ratio test 1 active lever presses1.01.010.40.1-0.1-0.00.1-0.1-0.40.2-0.30.21.3-0.90.03.2
Progressive ratio test 1 breakpoint1.01.09.40.4-0.4-0.30.4-0.4-0.10.6-0.50.40.9-1.20.43.1
Progressive ratio test 1 inactive lever presses0.50.51.7-0.50.50.6-0.50.5-1.1-0.70.6-0.50.8-0.3-0.61.3
Progressive ratio test 2 active lever presses0.70.74.80.4-0.3-0.30.4-0.40.40.2-0.60.70.6-1.70.32.2
Progressive ratio test 2 breakpoint1.01.25.20.8-0.7-0.80.8-0.80.60.7-0.91.10.3-1.80.72.3
Progressive ratio test 2 inactive lever presses0.30.41.1-0.40.50.6-0.40.4-0.8-0.70.6-0.41.1-0.6-0.50.8
Total sessions with >9 infusions0.20.21.80.10.00.10.1-0.1-0.10.0-0.4-0.00.6-0.9-0.11.3
Short access day 1 total inactive lever presses0.10.10.60.1-0.0-0.00.1-0.1-0.8-0.1-0.1-0.20.10.40.00.1
Short access day 10 total inactive lever presses1.01.06.8-0.80.80.8-0.80.80.3-1.00.8-0.6-0.70.2-0.9-2.6
Short access day 1 total infusions0.80.92.11.0-1.0-0.91.0-1.00.50.8-1.20.8-0.6-1.50.91.0
Short access day 10 total infusions1.41.611.41.0-0.9-0.91.0-1.0-0.21.0-1.20.30.3-0.80.93.4
Short access total infusions1.92.16.01.5-1.5-1.41.5-1.50.51.4-1.61.0-0.5-1.41.42.4
Short access day 1 locomotion0.20.21.10.2-0.1-0.10.2-0.20.20.3-0.30.40.2-1.00.10.9
Short access day 10 total locomotion0.30.30.7-0.40.50.5-0.40.4-0.9-0.20.4-0.80.8-0.2-0.50.6
Short access total locomotion0.30.42.60.00.00.10.0-0.0-0.70.2-0.0-0.20.9-0.8-0.01.6
Compulsive drug intake1.41.45.1-1.21.21.2-1.21.2-1.0-1.01.1-0.90.30.8-1.1-2.3
One hour access (0.3 mA shock)1.61.812.41.0-0.9-0.91.0-1.0-0.21.1-1.10.80.4-1.50.93.5
One hour access (shock baseline)2.22.617.81.3-1.2-1.21.3-1.30.21.1-1.41.00.3-1.41.14.2
Number of responses in last shaping day0.10.10.80.2-0.1-0.10.2-0.2-0.30.2-0.30.30.3-0.60.10.9
Context. condit. distance diff. score0.40.51.0-0.70.70.6-0.70.7-0.7-0.30.5-1.00.9-0.3-0.70.8
Locomotion velocity, session 10.40.41.70.5-0.5-0.50.5-0.50.80.5-0.30.6-0.9-0.10.5-1.3
Locomotion distance, session 10.40.52.70.5-0.4-0.60.5-0.51.60.8-0.20.5-0.7-0.80.5-0.6
Locomotion velocity, session 22.42.84.1-1.91.91.9-1.91.9-1.2-1.81.5-1.92.0-0.5-1.9-0.5
Locomotion distance, session 20.40.51.10.7-0.7-0.80.7-0.70.80.7-0.40.6-0.4-1.10.70.5
Locomotion velocity, session 32.32.73.5-1.81.81.7-1.81.8-1.3-1.91.9-1.81.9-0.4-1.80.3
Locomotion distance, session 30.20.21.20.3-0.3-0.40.3-0.30.30.10.3-0.20.1-0.40.31.1
Stereotopy head waving bouts, day 32.22.64.8-1.81.81.8-1.81.8-0.7-1.82.2-1.11.6-0.4-1.8-1.4
Stereotopy head waving duration, day 31.82.13.1-1.71.71.7-1.71.7-1.3-1.71.4-1.11.4-0.2-1.7-0.8
Locomotion velocity, session 70.30.32.50.0-0.0-0.10.0-0.00.90.20.3-0.20.0-1.60.00.3
Locomotion distance, session 70.00.00.2-0.00.0-0.0-0.00.00.0-0.10.4-0.30.10.2-0.0-0.2
Stereotopy head waving bouts, day 70.50.51.6-0.60.70.7-0.60.60.4-0.51.0-0.80.8-1.3-0.60.5
Stereotopy head waving duration, day 70.10.10.40.1-0.1-0.10.1-0.10.60.30.2-0.2-0.1-0.60.10.5
Locomotion velocity, session 80.80.92.0-1.01.01.1-1.01.0-1.4-0.60.5-1.00.9-1.0-1.00.9
Locomotion distance, session 80.50.84.70.5-0.4-0.60.5-0.50.21.0-0.3-0.00.4-1.60.52.2
Degree of sensitization distance0.20.21.3-0.10.10.2-0.10.1-0.9-0.1-0.2-0.0-0.10.6-0.1-1.1
Degree of sensitization stereotypy0.30.30.9-0.50.50.6-0.50.50.5-0.40.7-1.00.5-0.6-0.50.1
Condit. Reinf. active minus inactive responses2.02.34.41.5-1.5-1.51.5-1.51.61.3-1.51.6-2.1-0.61.5-1.3
Condit. Reinf. active-inactive response ratio2.42.55.21.7-1.7-1.71.7-1.71.31.5-1.71.7-2.3-0.21.7-0.7
Condit. Reinf. active responses1.72.04.31.3-1.3-1.41.3-1.31.71.1-1.31.6-2.1-0.11.3-1.7
Condit. Reinf. inactive responses0.20.32.3-0.10.10.1-0.10.10.6-0.20.00.2-0.50.3-0.1-1.5
Incentive salience index mean3.13.85.82.1-2.1-2.12.1-2.11.91.9-1.82.3-2.4-0.62.1-0.6
Condit. Reinf. lever presses1.21.62.81.4-1.3-1.41.4-1.41.61.2-0.71.7-1.3-0.51.40.1
Time in familiar zone, hab. session 10.10.10.90.0-0.10.10.0-0.00.4-0.30.1-0.3-0.3-1.00.0-0.6
Time in novel zone, hab. session 10.50.55.70.1-0.1-0.20.1-0.1-0.80.3-0.6-0.0-0.12.40.1-0.3
Total zone transitions, hab. session 12.53.55.41.9-1.8-2.01.9-1.92.32.0-1.42.0-1.4-2.21.91.0
Total locomotion distance, hab. session 12.94.29.52.0-1.9-2.12.0-2.02.82.0-1.62.1-1.5-3.12.00.4
Locomotion velocity, hab. session 14.26.116.22.3-2.2-2.42.3-2.33.42.4-1.82.6-1.8-4.02.30.9
Time in familiar zone, hab. session 20.30.30.80.6-0.7-0.50.6-0.60.30.4-0.70.4-0.9-0.40.6-0.2
Time in novel zone, hab. session 20.30.30.4-0.60.70.5-0.60.6-0.4-0.30.5-0.40.50.5-0.6-0.0
Total zone transitions, hab. session 21.92.44.31.7-1.6-1.81.7-1.71.72.1-1.21.4-1.6-0.81.70.3
Total locomotion distance, hab. session 24.66.18.52.6-2.5-2.62.6-2.62.72.9-2.02.5-2.6-2.42.60.0
Locomotion velocity, hab. session 24.56.18.32.6-2.5-2.52.6-2.62.82.9-1.92.5-2.6-2.72.60.1
Novel to familiar place preference ratio1.31.32.1-1.51.41.3-1.51.5-0.0-1.40.8-1.11.2-0.3-1.5-0.1
Novelty place preference1.21.32.1-1.41.41.3-1.41.4-0.2-1.40.7-1.01.0-0.2-1.4-0.1
Time in novel zone, NPP test0.80.81.4-1.21.11.0-1.21.2-0.2-1.10.4-0.90.80.1-1.2-0.0
Total zone transitions, NPP test0.81.22.71.3-1.2-1.31.3-1.30.21.6-0.50.9-0.7-0.91.31.0
Total locomotion distance, NPP test2.12.98.81.7-1.6-1.81.7-1.72.01.8-1.01.6-1.2-3.01.70.3
Locomotion velocity, NPP test1.31.99.41.1-1.1-1.21.1-1.11.91.3-0.41.3-0.8-3.11.1-0.0
Pavlov. Cond. lever latency0.10.10.60.0-0.1-0.10.0-0.0-0.7-0.2-0.2-0.50.4-0.20.00.7
Pavlov. Cond. magazine entry latency1.41.84.21.4-1.3-1.41.4-1.42.01.5-0.91.1-1.70.51.4-0.5
Pavlov. Cond. change in total contacts1.71.86.01.3-1.3-1.31.3-1.32.51.4-1.01.3-1.50.21.3-0.8
Pavlov. Cond. index score1.21.53.31.2-1.2-1.21.2-1.21.81.5-0.71.4-1.70.31.2-0.5
Pavlov. Cond. latency score0.70.93.00.8-0.8-0.80.8-0.81.71.1-0.31.2-1.40.20.8-0.5
Pavlov. Cond. lever contacts0.30.41.20.5-0.5-0.50.5-0.51.10.7-0.21.0-0.7-0.10.5-0.5
Pavlov. Cond. magazine entry number1.41.72.7-1.41.41.4-1.41.4-1.6-1.60.9-1.11.6-0.9-1.40.5
Pavlov. Cond. intertrial magazine entries0.70.92.61.1-1.1-1.01.1-1.1-0.20.8-1.60.4-0.80.61.10.1
Pavlov. Cond. lever-magazine prob. diff.1.51.83.21.4-1.4-1.41.4-1.41.81.7-0.91.4-1.80.21.4-0.5
Pavlov. Cond. response bias1.61.94.21.4-1.4-1.51.4-1.42.01.5-1.21.5-1.60.21.4-0.6
Bone: apparent density0.30.62.7-0.60.70.6-0.60.6-1.7-0.40.4-0.40.71.2-0.60.2
Bone surface0.10.20.60.5-0.5-0.50.5-0.5-0.80.6-0.60.5-0.20.50.50.2
Bone volume0.20.41.30.5-0.4-0.50.5-0.5-1.20.6-0.70.4-0.20.80.50.6
Bone: connectivity density1.11.72.0-1.41.41.4-1.41.4-1.4-1.31.2-0.81.31.3-1.4-1.2
Bone: cortical apparent density0.10.20.7-0.10.10.1-0.10.10.70.10.5-0.60.5-0.6-0.00.8
Bone: cortical area1.42.13.31.5-1.4-1.51.5-1.5-0.91.8-1.41.4-0.91.81.41.8
Bone: cortical porosity1.21.33.8-1.11.11.1-1.11.1-1.9-0.91.2-1.11.2-0.2-1.21.0
Bone: cortical porosity0.40.52.8-0.20.20.2-0.20.2-1.70.00.4-0.30.5-0.4-0.31.5
Bone: cortical thickness0.50.84.00.5-0.4-0.50.5-0.5-1.41.0-0.20.40.02.00.51.5
Bone: cortical thickness0.20.32.2-0.20.20.1-0.20.2-1.1-0.20.10.0-0.11.5-0.20.1
Bone: cortical tissue density0.20.20.6-0.20.20.2-0.20.20.6-0.10.5-0.70.6-0.7-0.10.8
Bone: elastic displacement0.60.74.5-0.60.50.5-0.60.6-0.9-0.60.3-0.2-0.70.7-0.6-2.1
Bone: elastic work1.11.55.3-1.11.01.0-1.11.1-2.3-1.10.6-0.90.11.7-1.1-1.5
Bone: endosteal estimation0.20.50.90.9-0.9-0.80.9-0.90.10.5-0.90.4-0.70.10.8-0.1
Bone: endosteal perimeter1.83.77.92.2-2.2-2.22.2-2.20.11.9-2.81.9-1.50.52.11.5
Bone: final force0.71.14.40.8-0.8-0.80.8-0.8-1.21.2-0.80.4-0.42.10.81.4
Bone: final moment0.81.35.01.0-1.0-1.01.0-1.0-1.31.4-0.90.7-0.72.21.01.1
Bone: marrow area0.20.40.80.8-0.8-0.80.8-0.80.20.5-0.90.4-0.70.10.7-0.1
Bone: maximum diameter1.93.46.62.0-2.1-2.02.0-2.0-0.12.0-2.61.7-1.40.82.01.8
Bone: maximum force0.30.62.30.6-0.5-0.60.6-0.6-0.90.9-0.50.2-0.41.50.61.0
Bone: maximum moment0.50.83.00.8-0.8-0.80.8-0.8-0.91.2-0.60.5-0.81.70.80.7
Bone: minimum diameter3.26.09.22.7-2.7-2.72.7-2.7-0.12.9-2.92.0-1.70.82.73.0
Bone: periosteal estimation0.71.42.11.3-1.3-1.31.3-1.3-0.71.2-1.40.9-0.81.11.21.1
Bone: periosteal perimeter1.32.24.01.6-1.6-1.61.6-1.6-0.71.6-2.01.4-1.11.01.61.2
Bone: post-yield work0.30.43.5-0.40.40.4-0.40.4-0.0-0.30.2-0.30.31.9-0.30.6
Bone: stiffness0.71.14.41.0-1.0-1.11.0-1.0-0.61.5-0.60.2-0.10.91.02.1
Bone: tissue strength0.20.10.50.3-0.2-0.30.3-0.30.00.60.40.10.10.70.30.6
Bone: trabecular number0.50.81.9-0.90.90.9-0.90.9-1.3-0.80.7-0.40.81.4-0.9-0.7
Bone: trabecular spacing0.10.20.70.0-0.0-0.00.0-0.00.8-0.50.00.1-0.3-0.60.0-0.8
Bone: trabecular thickness0.30.31.4-0.10.10.1-0.10.1-1.20.3-0.4-0.10.20.9-0.21.2
Bone: trabecular tissue density0.40.52.6-0.40.40.4-0.40.41.0-0.00.7-0.80.5-1.6-0.40.8
Breakpoint value in progressive ratio session0.40.41.70.5-0.5-0.50.5-0.5-0.00.4-0.40.6-1.3-0.40.4-1.2
Distance traveled before self-admin0.50.60.90.8-0.8-0.80.8-0.80.70.8-0.61.0-0.8-0.80.80.1
Distance traveled after self-admin0.80.91.41.2-1.2-1.11.2-1.2-0.61.0-0.90.2-0.5-0.21.11.0
Delta time in closed arm before/after self-admin1.31.22.61.0-1.0-1.21.0-1.01.61.0-1.21.3-1.4-0.81.1-0.1
Delta time in open arm before/after self-admin0.70.71.8-0.80.81.0-0.80.8-0.5-0.81.3-1.00.70.5-0.8-0.7
Diff in mean of infusions in LGA sessions0.30.41.80.4-0.5-0.50.4-0.40.20.4-0.70.5-1.4-0.00.5-1.0
Extinction: sum of active levers before priming0.10.10.50.1-0.1-0.20.1-0.10.0-0.2-0.0-0.1-0.50.50.0-0.7
Active lever presses in extinction session 61.71.62.31.5-1.5-1.41.5-1.51.41.4-0.61.3-1.4-0.31.5-0.4
Delta distance traveled before/after self-admin0.20.20.70.3-0.3-0.30.3-0.3-0.70.2-0.0-0.30.40.30.30.8
Delta ambulatory time before/after self-admin0.20.21.00.2-0.2-0.10.2-0.2-1.00.00.0-0.70.31.00.10.4
Time in closed arm before self-admin0.10.11.00.1-0.1-0.10.1-0.1-0.60.2-0.20.00.20.20.21.0
Time in closed arm after self-admin0.50.51.00.6-0.6-0.70.6-0.61.00.4-0.80.9-0.90.10.7-0.3
Time in open arm before self-admin0.10.10.4-0.20.20.0-0.20.20.4-0.3-0.10.3-0.20.2-0.3-0.6
Time in open arm after self-admin0.30.40.7-0.60.60.7-0.60.6-0.4-0.60.9-0.60.40.2-0.6-0.7
Sum of active levers in priming session hrs 5-63.73.64.92.1-2.1-2.12.1-2.11.72.2-1.82.0-2.2-0.32.10.5
Time to tail flick, vehicle, before self-admin1.11.14.21.0-0.9-0.91.0-1.00.71.1-1.01.5-0.42.10.90.5
Time to tail flick, vehicle, after self-admin0.70.71.31.0-1.0-1.11.0-1.00.41.0-0.70.4-1.20.11.1-0.2
Time to tail flick, test, before self-admin0.40.41.7-0.40.40.3-0.40.4-0.9-0.50.2-0.30.91.3-0.50.2
Time to tail flick, test, after self-admin0.20.20.30.3-0.3-0.30.3-0.30.50.6-0.30.6-0.4-0.10.4-0.5
Delta time to tail flick, vehicle, before/after SA0.30.31.30.3-0.3-0.40.3-0.30.40.2-0.1-0.3-1.0-1.10.4-0.8
Delta time to tail flick, test, before/after SA0.40.41.70.5-0.5-0.40.5-0.50.60.8-0.20.3-0.7-1.30.60.1
Ambulatory time before self-admin0.10.10.5-0.00.0-0.0-0.00.00.3-0.20.00.30.0-0.7-0.00.1
Ambulatory time after self-admin0.50.61.40.9-0.9-0.90.9-0.9-0.50.7-0.70.2-0.3-0.10.91.2
Total heroin consumption0.80.92.20.9-0.9-0.80.9-0.90.71.0-0.71.0-1.5-0.30.9-1.3
Area under the delay curve1.31.43.61.2-1.1-1.21.2-1.2-1.91.2-1.20.2-0.61.81.10.1
Delay disc. indifference point, 0s delay0.70.71.81.0-1.0-1.01.0-1.0-0.11.3-0.40.1-0.6-0.51.00.8
Delay disc. indifference point, 16s delay1.61.63.71.2-1.1-1.21.2-1.2-1.91.3-1.50.4-0.81.81.20.1
Delay disc. indifference point, 2s delay0.70.81.21.1-1.1-1.11.1-1.1-0.51.0-1.10.4-0.50.11.10.7
Delay disc. indifference point, 24s delay1.31.26.5-0.50.60.5-0.50.5-2.6-0.70.2-0.50.92.4-0.6-0.5
Delay disc. indifference point, 4s delay0.40.51.10.7-0.7-0.70.7-0.7-0.80.7-1.00.3-0.50.90.70.2
Delay disc. indifference point, 8s delay0.80.85.20.4-0.3-0.50.4-0.4-2.30.3-0.4-0.40.02.10.3-0.1
Delay discount exponential model param1.01.04.2-0.80.70.8-0.80.82.0-0.81.0-0.00.3-1.9-0.8-0.0
Delay discount hyperbolic model param1.01.13.5-1.00.91.0-1.01.01.9-0.91.1-0.20.4-1.7-0.9-0.2
Fecal boli incidents, locomotor time 11.11.22.5-1.01.11.1-1.01.0-0.6-1.11.6-0.81.51.2-1.00.2
Change in fecal boli incidents, locomotor task0.40.41.30.4-0.5-0.30.4-0.40.40.3-1.0-0.3-0.9-0.60.4-1.1
Time >=10cm from walls, locomotor time 10.80.81.60.9-0.9-0.90.9-0.90.71.2-0.80.3-1.3-1.30.9-0.3
Bouts of movement, locomotor time 10.10.20.80.2-0.2-0.40.2-0.2-0.70.4-0.10.2-0.20.90.20.4
Total resting periods, locomotor time 10.10.10.90.1-0.1-0.30.1-0.1-0.70.4-0.10.1-0.21.00.10.3
Rest time, locomotor task time 10.70.71.3-1.01.00.9-1.01.0-0.3-0.91.1-0.70.4-0.4-1.0-0.8
Distance moved, locomotor task time 12.42.63.21.8-1.8-1.71.8-1.81.81.5-1.71.5-1.3-1.61.80.9
Vertical activity count, locomotor time 14.24.35.52.4-2.3-2.32.4-2.42.22.2-2.02.1-1.9-1.22.40.7
Time >=10cm from walls, locomotor time 20.60.61.40.7-0.6-0.50.7-0.71.21.0-0.30.7-1.20.10.7-1.0
Bouts of movement, locomotor time 20.60.61.90.7-0.8-0.90.7-0.7-1.40.8-0.80.0-0.2-0.40.71.0
Total resting periods, locomotor time 20.70.71.40.9-0.9-1.10.9-0.9-1.20.9-0.90.1-0.4-0.30.90.8
Rest time, locomotor task time 20.20.20.90.3-0.3-0.30.3-0.30.70.0-0.30.1-0.9-0.50.3-0.5
Distance moved, locomotor task time 20.50.61.80.6-0.6-0.60.6-0.61.20.8-0.50.7-0.4-1.30.60.7
Vertical activity count, locomotor time 21.61.72.41.4-1.3-1.21.4-1.41.41.5-0.91.4-0.5-1.41.41.6
Weight adjusted by age1.21.32.11.2-1.2-1.31.2-1.20.91.2-0.80.7-0.6-1.41.21.4
Seeking ratio, delayed vs. immediate footshock0.50.62.4-0.50.60.5-0.50.5-1.1-0.41.10.10.51.6-0.6-0.2
Locomotion in novel chamber0.40.41.5-0.50.60.6-0.50.5-0.1-0.60.80.30.51.0-0.5-1.2
Locomotion in novel chamber post-restriction0.91.01.6-1.31.21.2-1.31.3-0.5-1.20.6-0.71.3-0.0-1.2-0.2
Progressive ratio0.70.81.6-0.80.90.8-0.80.8-1.2-0.81.1-1.20.7-0.4-0.9-0.9
Food seeking constrained by brief footshock0.30.43.20.2-0.2-0.10.2-0.2-0.90.2-0.3-0.30.9-0.40.21.8
Seeking ratio, punishment vs. effort0.50.62.10.7-0.8-0.60.7-0.70.20.7-1.10.7-0.20.30.81.5
Run reversals in cocaine runway, females0.10.10.5-0.00.0-0.1-0.00.0-0.5-0.00.30.30.3-0.70.00.7
Run reversals in cocaine runway, males0.30.31.40.4-0.4-0.50.4-0.41.20.5-0.50.3-0.60.90.50.1
Latency to leave start box in cocaine runway0.91.02.31.0-1.0-1.11.0-1.01.50.8-1.01.2-1.30.00.9-0.2
Latency to leave start box in cocaine runway, F1.82.04.81.5-1.4-1.51.5-1.52.21.3-1.31.0-1.8-1.11.4-0.0
Latency to leave start box in cocaine runway, M1.31.22.0-1.21.21.1-1.21.2-1.1-1.21.1-0.01.41.1-1.30.2
Cd content in liver1.31.52.41.3-1.3-1.31.3-1.30.51.4-1.10.9-0.9-1.01.31.6
Co content in liver0.40.43.20.3-0.3-0.30.3-0.3-0.4-0.1-0.60.30.5-0.90.31.8
Cu content in liver0.40.42.3-0.30.30.3-0.30.3-0.6-0.40.1-0.30.8-1.2-0.31.5
Fe content in liver0.30.41.7-0.30.30.3-0.30.3-1.0-0.20.2-0.70.81.0-0.31.3
K content in liver5.05.07.9-2.52.52.5-2.52.5-0.9-2.22.5-2.02.8-1.6-2.5-0.7
Mg content in liver0.90.93.3-0.91.00.9-0.90.9-0.1-0.80.8-0.81.2-1.8-0.9-0.4
Mn content in liver0.30.33.00.3-0.3-0.30.3-0.30.40.4-0.60.10.0-1.70.30.2
Na content in liver0.80.91.2-1.01.01.0-1.01.0-0.4-1.00.6-1.11.01.0-1.0-0.6
Rb content in liver4.35.48.3-2.52.52.5-2.52.5-2.9-2.52.2-2.12.80.9-2.5-0.5
Se content in liver0.40.52.8-0.20.20.2-0.20.21.3-0.30.3-0.80.4-1.7-0.20.6
Sr content in liver0.30.20.70.2-0.1-0.10.2-0.2-0.70.30.80.7-0.10.80.20.8
Zn content in liver0.40.41.4-0.50.50.5-0.50.5-0.6-0.60.2-0.80.6-1.2-0.50.8