Best TWAS P=7.89e-08 · Best GWAS P=1.23e-07 conditioned to 1.00e+00
Tissue | Gene | RNA modality | RNA phenotype | h2 | # weights | Model R2 | Model R2 P | TWAS Z | TWAS P | Coloc P | Joint |
---|---|---|---|---|---|---|---|---|---|---|---|
Adipose | Trappc13 | mRNA stability | Trappc13 | 0.11 | 29 | 0.04 | 3.1e-05 | 5.21 | 1.86e-07 | 0.62 | FALSE |
IL | LOC120100694 | gene expression | LOC120100694 | 0.41 | 20 | 0.22 | 6.0e-06 | -5.24 | 1.60e-07 | 0.43 | FALSE |
IL | Nln | gene expression | Nln | 0.13 | 12 | 0.06 | 1.3e-02 | -5.37 | 7.89e-08 | 0.29 | TRUE |
LHb | Trappc13 | gene expression | Trappc13 | 0.27 | 5 | 0.09 | 3.9e-03 | 5.22 | 1.82e-07 | 0.4 | FALSE |
LHb | Sgtb | mRNA stability | Sgtb | 0.32 | 1 | 0.05 | 2.9e-02 | -5.2 | 2.00e-07 | 0.05 | FALSE |
Liver | Nln | alternative TSS | NM_053970.2 | 0.08 | 1 | 0.07 | 9.5e-09 | 5.22 | 1.82e-07 | 0.72 | FALSE |
Liver | Nln | alternative TSS | NM_053970.2 | 0.08 | 1 | 0.06 | 1.6e-07 | 5.22 | 1.82e-07 | 0.72 | FALSE |
Liver | Nln | alternative TSS | XM_039101583.1 | 0.07 | 1 | 0.06 | 1.7e-07 | -5.22 | 1.82e-07 | 0.71 | FALSE |
NAcc | Trappc13 | gene expression | Trappc13 | 0.06 | 7 | 0.08 | 2.4e-09 | -5.21 | 1.86e-07 | 0.54 | FALSE |
NAcc | Nln | isoform ratio | NM_053970.2 | 0.03 | 1 | 0.03 | 5.4e-04 | -5.2 | 2.00e-07 | 0.11 | FALSE |
NAcc | Erbin | mRNA stability | Erbin | 0.02 | 1 | 0.02 | 3.5e-03 | -5.29 | 1.23e-07 | 0.1 | FALSE |
OFC | Cenpk | alternative TSS | XM_008760667.3 | 0.18 | 1 | 0.05 | 2.1e-02 | 5.2 | 2.00e-07 | 0.06 | FALSE |
OFC | Cenpk | alternative TSS | XM_008760667.3 | 0.17 | 1 | 0.05 | 2.7e-02 | 5.2 | 2.00e-07 | 0.06 | FALSE |
PL | Ppwd1 | alternative TSS | XM_039101929.1 | 0.16 | 59 | 0.16 | 1.3e-17 | 5.18 | 2.18e-07 | 0.56 | FALSE |
PL | Ppwd1 | alternative TSS | XM_039101930.1 | 0.16 | 1 | 0.16 | 1.4e-17 | -5.23 | 1.67e-07 | 0.8 | FALSE |
PL | Nln | gene expression | Nln | 0.07 | 1 | 0.08 | 3.6e-09 | -5.18 | 2.17e-07 | 0.69 | FALSE |
PL | Nln | isoform ratio | XM_039101583.1 | 0.03 | 29 | 0.03 | 1.2e-04 | 5.2 | 2.02e-07 | 0.49 | FALSE |
PL | Ppwd1 | isoform ratio | XM_006231887.4 | 0.02 | 1 | 0.02 | 2.3e-03 | 5.18 | 2.17e-07 | 0.05 | FALSE |