Hub : Genes

Slc7a1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000000924 0.1 0.1 1.4e-06 0.02 0.03 0.02 0.03 1.7e-03 9.4e-05 1.8e-03 7.4e-04
2 Adipose mRNA stability ENSRNOG00000000924 0.08 0.08 1.1e-06 0.06 0.04 0.05 0.06 4.2e-07 9.7e-06 2.5e-06 9.1e-07
3 BLA gene expression ENSRNOG00000000924 0.15 0.07 4.2e-06 0.08 0.09 0.08 0.07 5.7e-05 2.5e-05 5.2e-05 8.0e-05
4 BLA mRNA stability ENSRNOG00000000924 0.04 0.03 3.3e-03 0.02 0.03 0.01 0.02 3.8e-02 1.7e-02 5.0e-02 2.8e-02
5 Brain mRNA stability ENSRNOG00000000924 0.21 0.1 5.3e-15 0.16 0.16 0.16 0.16 3.0e-14 1.1e-14 4.3e-15 4.7e-15
6 IL mRNA stability ENSRNOG00000000924 0.16 0.11 4.3e-03 0.04 0.07 0.03 0.06 3.1e-02 9.0e-03 6.6e-02 2.0e-02
7 LHb mRNA stability ENSRNOG00000000924 0.17 0.11 6.6e-03 0.08 0.09 0.1 0.1 5.8e-03 3.9e-03 2.4e-03 2.8e-03
8 NAcc gene expression ENSRNOG00000000924 0.04 0.03 7.9e-04 0.03 0.03 0.02 0.02 4.7e-03 1.9e-03 2.0e-02 8.9e-03
9 NAcc mRNA stability ENSRNOG00000000924 0.11 0.07 4.5e-08 0.12 0.1 0.1 0.11 4.2e-09 7.4e-08 5.3e-08 2.3e-08
10 OFC gene expression ENSRNOG00000000924 0.13 0.08 9.2e-04 0.09 0.13 0.11 0.12 4.7e-03 6.0e-04 1.6e-03 1.0e-03
11 OFC mRNA stability ENSRNOG00000000924 0.2 0.15 8.0e-04 0.15 0.15 0.17 0.18 2.2e-04 2.4e-04 9.4e-05 4.8e-05
12 PL gene expression ENSRNOG00000000924 0.09 0.09 7.7e-03 0 0 -0 -0 1.2e-01 1.2e-01 4.7e-01 8.7e-01
13 PL mRNA stability ENSRNOG00000000924 0.13 0.07 5.4e-09 0.12 0.1 0.1 0.11 4.3e-09 5.8e-08 3.1e-08 1.8e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
BMI with tail0.72.33.6-1.7-1.8-0.1-1.7-1.3-1.2-1.5-1.8-1.9-1.8-1.4-1.3-1.3
BMI without tail0.61.22.20.51.20.81.21.31.00.91.01.01.11.11.11.5
Body weight2.08.426.01.32.65.12.34.32.72.71.72.51.82.92.72.8
Epididymis fat weight0.51.12.8-1.2-0.50.5-1.5-0.2-1.0-1.2-1.6-0.5-1.7-0.8-1.0-0.3
Glucose0.71.03.91.40.12.00.70.51.41.10.90.50.71.00.90.4
Heart weight0.50.82.1-0.10.70.21.51.40.80.71.10.51.30.70.60.3
Left kidney weight2.67.515.31.52.63.92.43.62.62.72.02.82.12.82.92.9
Right kidney weight3.18.823.31.83.34.82.03.72.52.91.63.31.73.03.13.3
Tail length8.024.233.94.05.34.65.05.84.64.84.65.14.85.14.85.1
Length with tail9.233.753.84.55.97.05.57.35.65.84.95.85.26.05.65.6
Length without tail2.24.817.81.31.94.21.43.22.12.21.11.91.22.12.11.7
Liver weight, left0.30.52.1-0.00.91.2-0.31.0-0.10.1-0.40.9-0.30.30.51.5
Liver weight, right2.54.29.91.92.23.21.32.31.81.91.32.01.32.12.22.4
Parametrial fat weight0.20.31.1-0.70.80.20.41.0-0.0-0.20.01.10.20.30.30.8
Retroperitoneal fat weight0.10.42.30.00.81.5-0.60.40.20.1-0.40.9-0.60.40.40.6
Intraocular pressure0.60.91.7-1.3-0.4-1.1-0.9-0.1-1.2-1.3-1.1-0.6-1.0-0.9-1.2-0.7
Extensor digitorum longus weight0.41.64.30.91.82.10.41.70.80.70.31.80.41.30.81.5
Soleus weight0.30.93.20.11.61.00.01.20.10.2-0.11.8-0.00.70.51.7
Tibialis anterior weight0.20.83.7-0.11.01.30.61.90.40.50.21.10.40.80.51.0
Tibia length0.71.96.90.41.51.61.52.61.21.21.11.31.31.30.80.9
Number of licking bursts1.21.42.50.91.41.50.91.61.01.10.81.40.81.21.11.4
Food consumed during 24 hour testing period0.81.01.51.20.70.51.10.31.11.21.20.71.21.01.20.8
Times rat made contact with spout0.91.01.41.20.90.91.00.81.01.01.00.91.11.01.11.1
Mean time between licks in bursts1.82.54.5-2.0-1.3-2.1-1.1-1.1-1.8-1.8-1.4-1.4-1.2-1.6-1.7-1.5
Mean num. licks in bursts0.60.71.8-0.3-1.1-1.1-0.5-1.4-0.6-0.7-0.4-1.1-0.4-0.8-0.6-1.0
Std. dev. time between licks in bursts0.40.50.90.50.40.60.90.70.90.60.90.50.90.80.40.2
Water consumed over 24 hours1.51.82.60.91.41.11.61.61.31.41.41.21.51.31.31.3
Indifference point 0 sec0.40.72.11.00.61.40.40.70.81.00.50.40.40.71.00.8
Indifference point AUC0.40.51.40.90.31.20.60.60.90.60.60.10.60.70.70.5
Indifference point function ln k0.20.30.60.30.50.60.50.40.40.80.40.80.50.40.70.3
Indifference point function log k0.20.30.60.30.50.60.50.40.40.80.40.80.50.40.70.3
Delay discounting total patch changes 0 sec0.50.71.91.10.71.40.40.70.81.10.60.50.50.81.10.9
Delay discounting total patch changes 12 sec0.60.83.21.40.21.80.30.51.11.00.60.00.40.81.00.7
Delay discounting total patch changes 18 sec0.60.91.7-0.5-1.0-0.4-1.3-1.0-1.0-0.8-1.1-1.0-1.2-1.0-0.5-0.7
Delay discounting total patch changes 24 sec1.01.32.81.70.81.60.80.71.41.21.10.50.91.21.31.1
Delay discounting total patch changes 6 sec1.42.13.11.81.11.71.31.21.61.71.51.11.41.51.61.4
Delay discounting time to switch 0 sec0.71.12.6-1.2-0.4-1.6-1.0-0.9-1.2-1.2-1.0-0.2-1.0-0.9-1.2-0.7
Delay discounting water rate 0 sec0.10.10.4-0.0-0.40.60.20.40.10.1-0.1-0.70.1-0.10.3-0.2
Delay discounting water rate 12 sec0.30.41.00.20.50.80.60.70.40.80.30.80.50.41.00.6
Delay discounting water rate 18 sec1.82.34.62.11.41.31.30.81.61.61.51.51.51.51.71.6
Delay discounting water rate 24 sec0.40.51.5-1.2-0.9-1.00.1-0.1-0.8-0.5-0.4-0.8-0.1-0.8-0.5-0.8
Delay discounting water rate 6 sec0.10.20.5-0.20.10.1-0.7-0.4-0.6-0.3-0.70.2-0.6-0.40.20.2
Locomotor activity1.01.63.21.21.21.81.01.71.31.31.00.91.01.21.21.3
Locomotor testing distance0.20.30.6-0.5-0.40.0-0.7-0.3-0.6-0.3-0.8-0.6-0.7-0.6-0.4-0.4
Locomotor testing rearing0.71.11.4-1.1-0.8-1.1-1.0-1.0-1.2-0.9-1.1-1.1-1.0-1.2-0.9-0.9
Light reinforcement 10.40.72.31.50.70.90.2-0.10.90.70.70.80.41.00.70.9
Light reinforcement 20.30.31.21.10.31.1-0.8-0.60.20.1-0.40.3-0.60.40.10.2
Reaction time number correct0.30.41.00.00.60.70.71.00.40.70.40.80.60.50.60.2
Reaction time mean minus median1.11.42.80.51.5-0.91.41.30.60.51.31.71.41.00.61.7
Reaction time mean minus median AUC1.01.32.40.51.3-1.01.51.20.50.71.31.61.50.90.81.4
Reaction time num false alarms1.52.02.91.61.41.61.11.51.41.61.21.11.11.51.71.6
Reaction time num false alarms AUC1.42.02.91.61.61.70.81.41.31.41.01.30.91.51.61.7
Reaction time trials correct on left0.30.41.00.00.60.70.71.00.40.70.40.80.60.50.60.2
Reaction time trials on left0.30.41.00.00.60.70.71.00.40.70.40.80.60.50.60.2
Reaction time mean1.72.47.3-1.3-1.5-2.7-1.1-1.8-1.5-1.6-1.0-1.3-1.0-1.5-1.6-1.3
Reaction time mean AUC2.43.29.0-1.6-1.6-3.0-1.4-2.0-1.9-1.9-1.3-1.3-1.3-1.8-1.9-1.5
Median of all reaction times3.85.19.1-1.9-2.4-3.0-2.1-2.7-2.2-2.3-1.9-2.1-2.0-2.3-2.2-2.2
Reaction time omissions0.50.62.9-0.9-0.5-1.7-0.4-0.4-1.0-0.8-0.5-0.3-0.4-0.7-1.0-0.7
Reaction time false alarm rate0.81.12.11.41.11.40.40.91.01.00.70.80.61.11.21.5
Reaction time premature initiation rate3.04.07.42.41.60.42.50.82.22.22.71.82.71.91.71.7
Reaction time premature initiations2.84.07.12.01.70.62.61.22.12.32.61.92.71.91.81.6
Std. dev. reaction times0.30.52.5-0.20.7-1.60.70.5-0.2-0.10.60.80.70.2-0.10.8
Reaction time trials completed0.30.41.00.00.60.70.71.00.40.70.40.80.60.50.60.2
Reaction time trials AUC0.20.30.80.00.50.70.60.90.40.70.40.70.50.40.60.1
Social response proportion0.10.10.6-0.30.4-0.20.50.70.0-0.20.20.40.40.3-0.2-0.4
Social responses3.84.96.12.42.51.42.32.02.12.22.32.52.42.42.22.0
Social time0.20.20.5-0.20.1-0.5-0.5-0.7-0.4-0.5-0.40.2-0.5-0.3-0.5-0.5
Conditioned locomotion1.41.72.9-1.3-1.4-1.7-1.0-0.9-1.4-1.5-1.1-1.1-1.0-1.3-1.6-1.5
Cocaine response after cond. corrected0.91.01.5-1.2-0.9-1.2-1.0-0.8-1.0-1.1-0.9-0.5-1.1-1.1-0.9-0.9
Cocaine response after cond. not corrected0.60.61.1-1.0-0.4-1.0-0.9-0.5-0.9-1.0-0.8-0.1-0.9-0.8-0.8-0.6
Cocaine response before conditioning1.72.13.41.51.81.41.21.41.51.31.31.71.31.61.21.5
Saline control response2.53.34.91.61.81.22.21.71.72.02.02.02.21.71.91.3
Condit. Reinf. active minus inactive responses1.51.82.61.61.30.91.50.81.41.41.61.21.61.41.31.2
Condit. Reinf. active-inactive response ratio2.62.73.92.01.51.21.71.11.71.71.81.51.81.71.71.7
Condit. Reinf. active responses2.43.34.32.11.61.62.01.32.02.02.11.42.11.91.71.4
Condit. Reinf. inactive responses1.01.21.91.10.71.21.30.91.31.41.30.71.31.11.10.5
Condit. Reinf. lever presses1.21.62.71.21.61.21.11.11.31.31.21.61.21.41.21.2
Condit. Reinf. lever reinforcers received2.63.74.72.11.71.72.11.52.22.12.21.52.22.01.81.5
Pavlov. Cond. lever latency0.40.50.8-0.9-0.8-0.4-0.7-0.3-0.9-0.5-0.9-0.9-0.8-0.8-0.4-0.4
Pavlov. Cond. magazine entry latency0.30.30.7-0.70.2-0.7-0.40.4-0.6-0.8-0.5-0.1-0.4-0.3-0.9-0.3
Pavlov. Cond. change in total contacts0.30.40.50.60.70.60.70.40.70.60.70.70.70.70.50.4
Pavlov. Cond. index score0.30.40.70.60.80.30.80.80.70.40.80.80.80.80.30.4
Pavlov. Cond. latency score0.30.40.70.50.80.30.70.70.60.40.70.80.70.70.30.4
Pavlov. Cond. lever contacts0.10.20.40.60.30.10.4-0.20.60.20.60.40.40.40.10.0
Pavlov. Cond. magazine entry number0.10.10.20.4-0.30.50.1-0.40.30.40.1-0.10.10.00.50.1
Pavlov. Cond. intertrial magazine entries1.41.83.21.60.61.21.70.71.81.61.80.71.81.31.30.5
Pavlov. Cond. lever-magazine prob. diff.0.40.50.80.60.90.40.80.80.70.40.80.90.80.90.30.5
Pavlov. Cond. response bias0.10.10.30.30.4-0.30.40.10.40.00.50.40.40.3-0.10.0
Conditioned reinforcement - actives1.91.84.30.91.42.01.02.11.21.30.91.30.91.31.31.3
Conditioned reinforcement - inactives0.30.41.60.50.11.30.40.80.80.70.4-0.30.40.50.70.1
Conditioned locomotion4.55.57.32.72.62.71.71.92.32.52.02.51.92.42.62.3
Intermittent access intake day 1-15 change0.90.91.9-1.2-0.8-1.2-0.6-0.7-1.0-1.2-0.9-0.6-0.6-1.0-1.4-0.8
Intermittent access intake escalation1.01.02.0-1.3-0.9-1.2-0.6-0.7-1.0-1.2-0.9-0.7-0.7-1.1-1.4-0.9
Intermittent access intake escalation 24.03.95.6-2.2-1.9-2.3-1.5-1.8-2.0-2.3-1.8-1.7-1.5-2.1-2.4-2.0
Intermitt. access day 1 inactive lever presses0.40.41.20.90.11.10.40.10.80.90.5-0.00.40.60.90.4
Intermitt. access day 15 inactive lever presses1.41.62.91.70.71.71.00.41.61.61.30.61.11.31.50.9
Intermitt. access escalation Index1.41.32.1-1.4-0.7-1.5-1.0-0.6-1.4-1.2-1.2-0.8-1.1-1.1-1.2-0.9
Intermittent access day 1 total infusions0.50.61.60.10.20.01.01.30.60.70.9-0.00.90.61.10.5
Intermittent access day 15 total infusions0.20.20.7-0.8-0.4-0.80.60.8-0.1-0.10.3-0.40.5-0.2-0.0-0.1
Intermittent access terminal intake (last 3 days)0.10.10.6-0.6-0.6-0.70.20.1-0.2-0.20.0-0.60.1-0.4-0.0-0.3
Intermittent access total infusions0.30.41.0-0.10.1-0.41.00.90.50.50.8-0.10.90.40.70.2
Intermittent access day 1 locomotion0.30.30.70.50.00.10.60.20.50.70.7-0.10.70.40.90.0
Intermittent access day 15 total locomotion1.71.83.41.40.90.61.81.11.61.41.80.91.81.41.31.0
Intermittent access total locomotion1.41.63.11.21.00.41.70.91.51.31.80.81.71.31.40.8
Intermittent access standard deviation0.10.10.5-0.1-0.70.2-0.1-0.2-0.00.1-0.1-0.7-0.1-0.20.0-0.5
Cocaine induced anxiety0.10.10.3-0.4-0.2-0.3-0.3-0.1-0.3-0.2-0.3-0.5-0.3-0.30.2-0.1
Post-drug Anxiety0.60.73.2-1.3-0.6-1.8-0.2-0.3-0.9-0.8-0.4-0.8-0.3-0.8-0.3-0.4
Baseline Anxiety0.20.20.5-0.4-0.4-0.7-0.2-0.7-0.3-0.5-0.2-0.1-0.2-0.4-0.5-0.4
Lifetime Intake0.30.30.8-0.0-0.1-0.00.90.80.60.50.7-0.30.80.40.70.1
Incentive Sensitization - Responses0.70.72.3-1.3-0.5-0.71.31.50.20.10.7-0.71.0-0.1-0.4-0.5
Incentive Sensitization - Breakpoint0.70.72.4-1.3-0.5-0.71.31.50.20.10.7-0.61.0-0.1-0.4-0.4
Progressive ratio test 1 active lever presses2.42.44.01.51.31.81.51.61.71.61.51.31.51.62.01.3
Progressive ratio test 1 breakpoint1.81.93.31.31.01.51.41.41.51.51.41.01.41.41.81.1
Progressive ratio test 1 inactive lever presses1.71.83.51.41.11.91.21.61.51.41.20.71.21.51.51.0
Progressive ratio test 2 active lever presses0.60.62.5-0.80.0-0.21.51.60.50.40.9-0.01.20.30.4-0.0
Progressive ratio test 2 breakpoint0.60.73.0-0.60.1-0.11.51.70.60.41.00.11.30.50.40.1
Progressive ratio test 2 inactive lever presses1.21.44.00.00.60.81.82.01.21.21.40.31.51.01.10.6
Total sessions with >9 infusions0.70.81.60.90.61.30.80.71.01.00.70.60.81.01.20.7
Short access day 1 total inactive lever presses4.24.68.22.11.22.92.22.62.52.52.11.02.12.12.21.6
Short access day 10 total inactive lever presses0.30.30.60.60.30.20.70.40.60.70.8-0.30.80.50.70.4
Short access day 1 total infusions0.10.10.3-0.3-0.40.3-0.40.4-0.3-0.2-0.5-0.5-0.4-0.20.2-0.0
Short access day 10 total infusions1.71.93.11.41.11.51.21.41.51.41.31.01.31.51.81.1
Short access total infusions0.30.40.90.5-0.10.80.60.80.80.70.6-0.20.60.60.90.1
Short access day 1 locomotion0.30.30.90.90.50.90.10.00.50.60.20.40.20.50.90.3
Short access day 10 total locomotion0.30.31.50.90.31.20.10.40.60.60.20.10.10.50.50.1
Short access total locomotion0.80.82.61.60.61.10.60.11.01.10.80.40.71.01.20.5
Compulsive drug intake0.50.51.40.1-1.0-0.5-0.4-1.2-0.2-0.4-0.2-0.8-0.3-0.6-1.1-1.1
One hour access (0.3 mA shock)0.30.31.10.2-0.30.01.00.40.80.50.9-0.41.00.40.1-0.2
One hour access (shock baseline)0.60.71.60.20.60.31.11.30.80.70.90.31.00.71.00.8
Number of responses in last shaping day0.40.41.20.1-0.1-0.1-1.1-1.1-0.7-0.5-0.8-0.0-0.9-0.4-0.1-0.0
Context. condit. distance diff. score0.60.71.50.91.21.20.30.80.70.50.41.10.40.90.61.1
Locomotion velocity, session 11.71.83.31.80.91.61.21.11.61.41.40.71.31.41.31.2
Locomotion distance, session 10.00.10.10.1-0.30.10.3-0.20.30.20.3-0.20.30.00.2-0.2
Locomotion velocity, session 20.30.30.90.40.11.00.60.70.70.50.50.00.50.60.30.3
Locomotion distance, session 20.71.02.40.70.20.81.51.21.21.01.30.21.40.90.80.7
Locomotion velocity, session 31.11.23.11.61.01.80.50.71.21.20.80.60.61.11.21.2
Locomotion distance, session 31.11.22.00.90.90.81.21.11.11.41.20.41.21.01.41.0
Stereotopy head waving bouts, day 30.10.10.5-0.00.20.3-0.10.7-0.2-0.4-0.30.5-0.10.1-0.40.2
Stereotopy head waving duration, day 30.20.30.70.20.1-0.1-0.8-0.4-0.6-0.8-0.70.3-0.7-0.2-0.70.1
Locomotion velocity, session 70.60.61.91.41.00.50.50.30.90.30.80.80.61.00.31.0
Locomotion distance, session 70.10.10.60.30.3-0.80.30.10.1-0.40.40.00.40.3-0.40.4
Stereotopy head waving bouts, day 71.92.12.91.41.60.61.61.21.31.61.71.51.71.41.61.4
Stereotopy head waving duration, day 71.31.62.11.41.31.11.20.91.31.41.31.11.31.31.41.1
Locomotion velocity, session 82.22.74.72.21.31.81.61.02.01.61.81.51.71.71.51.3
Locomotion distance, session 80.81.21.81.01.11.41.11.31.10.81.00.81.01.20.91.2
Degree of sensitization distance0.70.72.1-0.6-0.7-1.3-0.6-0.8-0.6-1.4-0.5-0.3-0.5-0.6-1.5-0.7
Degree of sensitization stereotypy0.80.91.40.81.20.51.00.70.91.11.00.81.00.91.20.8
Condit. Reinf. active minus inactive responses0.70.81.4-0.7-0.7-0.2-1.1-0.9-1.0-0.9-1.2-0.4-1.1-0.9-0.8-0.8
Condit. Reinf. active-inactive response ratio4.65.05.9-2.0-2.2-1.9-2.4-2.4-2.4-2.3-2.4-1.9-2.4-2.4-2.1-2.3
Condit. Reinf. active responses0.10.20.3-0.3-0.40.1-0.6-0.4-0.4-0.4-0.6-0.3-0.6-0.4-0.3-0.4
Condit. Reinf. inactive responses1.61.92.51.61.31.61.11.21.51.51.30.81.21.41.41.6
Incentive salience index mean0.10.20.40.40.50.60.10.40.30.30.10.60.10.40.40.5
Condit. Reinf. lever presses0.40.51.20.71.00.70.30.70.60.60.40.80.30.80.61.1
Time in familiar zone, hab. session 10.40.40.6-0.7-0.6-0.3-0.6-0.8-0.6-0.6-0.6-0.4-0.6-0.6-0.6-0.8
Time in novel zone, hab. session 10.00.00.1-0.10.10.00.00.3-0.1-0.0-0.1-0.4-0.00.0-0.00.2
Total zone transitions, hab. session 13.34.67.81.42.20.82.82.32.02.12.52.32.72.02.12.0
Total locomotion distance, hab. session 10.20.31.0-0.40.6-1.00.80.6-0.00.00.50.50.70.10.10.4
Locomotion velocity, hab. session 10.30.40.90.20.7-0.70.90.60.40.40.90.61.00.40.50.5
Time in familiar zone, hab. session 21.31.42.1-0.6-1.4-0.6-1.2-1.4-0.9-1.4-1.1-1.3-1.2-1.0-1.4-1.4
Time in novel zone, hab. session 20.40.40.70.40.70.30.70.80.50.80.60.50.70.60.80.9
Total zone transitions, hab. session 20.20.30.8-0.40.3-0.20.90.90.20.50.50.10.70.20.40.3
Total locomotion distance, hab. session 20.20.31.2-0.9-0.4-1.10.20.2-0.5-0.2-0.0-0.60.1-0.5-0.3-0.4
Locomotion velocity, hab. session 20.20.31.4-1.0-0.4-1.20.30.2-0.5-0.2-0.0-0.60.2-0.5-0.3-0.4
Novel to familiar place preference ratio0.10.10.4-0.2-0.4-0.10.10.10.0-0.00.0-0.60.0-0.2-0.2-0.5
Novelty place preference0.10.10.4-0.2-0.5-0.10.00.1-0.0-0.1-0.0-0.7-0.0-0.2-0.3-0.6
Time in novel zone, NPP test0.10.10.3-0.1-0.40.10.10.10.10.00.1-0.60.1-0.1-0.2-0.5
Total zone transitions, NPP test1.52.22.71.21.31.41.61.41.41.51.41.61.51.41.61.6
Total locomotion distance, NPP test0.91.21.80.81.10.41.31.01.01.11.21.21.31.11.21.3
Locomotion velocity, NPP test0.81.11.80.61.10.11.31.10.81.01.21.21.31.01.11.3
Pavlov. Cond. lever latency1.01.32.5-1.5-1.2-0.2-1.0-0.8-1.1-1.0-1.3-1.1-1.2-1.3-1.0-1.6
Pavlov. Cond. magazine entry latency2.63.44.51.52.00.82.11.81.61.82.02.12.11.91.82.0
Pavlov. Cond. change in total contacts2.93.04.92.22.01.41.31.21.71.71.62.01.41.91.72.2
Pavlov. Cond. index score2.73.44.81.92.01.01.81.71.71.82.01.91.92.01.82.2
Pavlov. Cond. latency score2.32.93.81.81.70.81.71.51.61.71.91.71.91.81.71.9
Pavlov. Cond. lever contacts1.31.62.91.51.40.31.10.91.21.11.41.41.21.41.21.7
Pavlov. Cond. magazine entry number3.84.86.6-1.8-2.5-1.1-2.3-2.2-1.9-2.1-2.3-2.6-2.3-2.2-2.2-2.6
Pavlov. Cond. intertrial magazine entries0.91.02.6-0.8-1.2-0.7-1.0-0.9-0.9-0.7-1.0-1.6-1.0-1.1-0.8-1.2
Pavlov. Cond. lever-magazine prob. diff.2.02.53.91.61.80.81.51.51.51.51.71.71.61.71.52.0
Pavlov. Cond. response bias2.63.25.21.72.00.91.71.71.51.71.82.11.81.91.72.3
Bone: apparent density2.03.47.6-2.8-1.7-0.4-1.8-0.1-1.9-1.9-2.3-1.8-2.1-1.8-2.1-1.4
Bone surface0.71.23.8-1.9-0.60.2-1.00.6-1.1-1.2-1.5-0.9-1.3-1.0-1.3-0.5
Bone volume1.52.55.4-2.3-1.1-0.1-1.8-0.1-1.7-1.7-2.2-1.3-2.1-1.5-1.8-0.9
Bone: connectivity density0.81.34.5-2.1-0.9-0.3-0.70.7-1.2-1.2-1.4-1.0-1.1-1.0-1.4-0.6
Bone: cortical apparent density4.55.88.3-2.9-2.3-2.6-2.2-2.0-2.8-2.3-2.5-2.1-2.3-2.7-2.2-2.2
Bone: cortical area0.40.61.9-0.21.11.30.01.40.20.3-0.20.8-0.10.50.41.1
Bone: cortical porosity1.21.32.91.70.91.30.80.41.31.11.11.20.91.21.11.0
Bone: cortical porosity1.31.43.61.90.91.30.90.21.41.21.21.21.11.21.31.1
Bone: cortical thickness0.71.23.4-1.8-0.3-0.5-1.20.2-1.5-1.3-1.6-0.4-1.4-1.0-1.0-0.1
Bone: cortical thickness0.40.42.4-1.0-0.7-1.60.1-0.2-0.7-0.5-0.2-0.30.0-0.7-0.4-0.4
Bone: cortical tissue density5.06.68.8-3.0-2.5-2.7-2.4-2.2-2.9-2.5-2.6-2.3-2.5-2.9-2.3-2.4
Bone: elastic displacement1.01.12.5-1.1-1.6-1.0-0.6-1.0-0.9-0.9-0.8-1.4-0.7-1.2-0.7-1.4
Bone: elastic work0.10.20.4-0.5-0.60.10.60.60.20.10.2-0.40.4-0.00.1-0.3
Bone: endosteal estimation0.91.92.81.01.01.61.71.61.51.51.41.21.51.31.31.0
Bone: endosteal perimeter1.83.66.91.72.02.61.72.12.01.91.61.81.62.01.71.8
Bone: final force0.40.71.10.60.71.00.81.00.80.80.70.90.70.90.81.0
Bone: final moment0.20.30.70.30.40.80.50.80.50.50.40.70.50.60.60.8
Bone: marrow area0.81.82.80.90.91.51.71.61.51.41.41.11.51.31.21.0
Bone: maximum diameter0.51.03.00.21.31.70.51.50.60.80.21.10.40.90.81.2
Bone: maximum force0.81.42.60.81.21.41.01.61.01.10.91.30.91.21.11.4
Bone: maximum moment0.50.81.90.51.01.20.71.40.70.80.61.10.61.00.81.2
Bone: minimum diameter0.40.81.20.91.11.10.60.90.90.80.70.90.61.00.71.1
Bone: periosteal estimation0.71.33.40.41.31.61.01.81.01.00.71.20.81.10.91.4
Bone: periosteal perimeter1.32.25.31.21.72.31.01.81.41.31.01.51.01.61.21.7
Bone: post-yield work0.20.20.7-0.30.1-0.1-0.8-0.1-0.6-0.5-0.8-0.1-0.8-0.2-0.50.1
Bone: stiffness2.64.24.82.01.92.12.02.22.12.22.01.91.92.21.92.1
Bone: tissue strength0.80.81.2-1.1-0.8-0.5-0.9-0.6-1.0-1.0-1.1-0.6-1.0-0.9-0.8-0.9
Bone: trabecular number1.21.94.8-2.2-1.2-0.5-1.20.3-1.5-1.5-1.7-1.3-1.4-1.3-1.7-1.0
Bone: trabecular spacing0.10.10.40.50.3-0.00.2-0.30.30.40.40.40.30.30.60.2
Bone: trabecular thickness1.11.33.2-1.8-0.90.0-1.3-0.3-1.3-1.0-1.6-0.9-1.5-1.2-1.1-0.7
Bone: trabecular tissue density2.63.74.91.91.92.11.61.52.02.21.81.91.71.92.12.0
Breakpoint value in progressive ratio session0.80.93.00.01.40.00.81.70.30.40.61.10.70.80.61.4
Distance traveled before self-admin0.20.20.70.20.00.0-0.8-0.8-0.3-0.5-0.6-0.0-0.7-0.2-0.2-0.1
Distance traveled after self-admin0.40.41.11.00.90.7-0.1-0.20.40.50.21.00.10.60.90.7
Delta time in closed arm before/after self-admin1.91.85.02.10.52.21.10.81.81.61.30.51.11.51.10.9
Delta time in open arm before/after self-admin1.51.43.8-1.1-1.4-1.9-0.5-1.3-0.9-0.7-0.5-1.6-0.5-1.3-1.1-1.6
Diff in mean of infusions in LGA sessions0.20.21.00.61.0-0.2-0.20.2-0.10.10.00.7-0.10.40.30.7
Extinction: sum of active levers before priming0.10.10.2-0.2-0.10.3-0.20.40.1-0.4-0.2-0.5-0.30.0-0.4-0.1
Active lever presses in extinction session 60.40.30.9-0.80.00.0-0.80.1-0.7-0.7-0.90.4-0.9-0.4-0.50.1
Delta distance traveled before/after self-admin0.20.20.40.50.40.10.50.30.40.60.60.60.60.40.50.3
Delta ambulatory time before/after self-admin0.10.10.60.40.50.0-0.0-0.20.00.30.10.80.10.20.40.4
Time in closed arm before self-admin0.10.20.7-0.80.3-0.3-0.20.1-0.6-0.3-0.50.2-0.3-0.40.20.2
Time in closed arm after self-admin1.71.73.21.31.41.80.81.11.01.40.81.30.91.31.71.7
Time in open arm before self-admin0.20.31.0-0.6-0.4-0.3-0.30.3-0.5-0.9-0.5-0.1-0.4-0.3-1.0-0.4
Time in open arm after self-admin1.01.12.0-1.0-1.1-1.4-0.7-0.6-0.9-1.0-0.7-1.3-0.7-1.0-1.3-1.4
Sum of active levers in priming session hrs 5-60.10.10.5-0.50.1-0.10.30.70.1-0.20.10.00.20.1-0.4-0.1
Time to tail flick, vehicle, before self-admin0.10.10.40.1-0.2-0.2-0.3-0.6-0.1-0.3-0.10.1-0.2-0.10.20.3
Time to tail flick, vehicle, after self-admin1.61.73.51.01.70.91.20.91.21.11.21.91.21.41.51.5
Time to tail flick, test, before self-admin1.51.53.30.51.81.30.81.10.71.20.71.80.71.21.61.5
Time to tail flick, test, after self-admin0.00.00.20.1-0.20.0-0.0-0.50.10.30.10.1-0.0-0.10.2-0.4
Delta time to tail flick, vehicle, before/after SA0.10.10.20.20.40.30.30.10.40.50.30.10.30.30.5-0.0
Delta time to tail flick, test, before/after SA0.30.30.7-0.2-0.8-0.7-0.3-0.5-0.3-0.2-0.2-0.8-0.3-0.6-0.6-0.8
Ambulatory time before self-admin0.20.20.50.70.70.4-0.40.10.10.0-0.10.4-0.20.40.40.6
Ambulatory time after self-admin0.70.82.01.41.01.1-0.0-0.10.60.70.41.30.20.81.21.1
Total heroin consumption0.20.20.50.00.7-0.6-0.50.2-0.4-0.5-0.30.7-0.40.0-0.20.4
Area under the delay curve0.91.01.91.40.70.61.10.41.30.81.31.11.21.20.60.9
Delay disc. indifference point, 0s delay0.00.00.10.10.10.10.1-0.10.1-0.00.10.20.10.20.00.2
Delay disc. indifference point, 16s delay0.70.71.61.30.31.00.6-0.21.10.80.80.90.70.80.60.9
Delay disc. indifference point, 2s delay0.40.41.10.50.4-0.51.00.40.70.11.00.61.00.7-0.10.3
Delay disc. indifference point, 24s delay1.01.02.31.50.71.20.70.31.21.01.01.10.81.10.80.9
Delay disc. indifference point, 4s delay0.00.00.10.2-0.2-0.2-0.1-0.40.1-0.40.1-0.0-0.10.1-0.4-0.2
Delay disc. indifference point, 8s delay0.20.20.60.60.1-0.10.6-0.20.60.30.70.30.70.40.10.2
Delay discount exponential model param0.80.81.6-1.3-0.6-0.4-1.0-0.3-1.2-0.7-1.2-1.0-1.1-1.1-0.4-0.7
Delay discount hyperbolic model param0.70.71.4-1.2-0.6-0.3-1.0-0.3-1.1-0.5-1.2-1.0-1.1-1.0-0.3-0.7
Fecal boli incidents, locomotor time 12.42.67.22.11.12.71.21.12.01.91.41.11.21.71.41.2
Change in fecal boli incidents, locomotor task0.60.61.8-0.8-0.5-1.3-0.3-0.7-0.6-0.8-0.3-0.8-0.3-0.8-1.0-1.1
Time >=10cm from walls, locomotor time 10.60.61.7-1.2-1.3-0.90.1-0.3-0.4-0.5-0.1-1.2-0.0-0.7-0.4-0.8
Bouts of movement, locomotor time 10.50.61.91.30.31.40.3-0.20.91.00.50.20.40.61.00.4
Total resting periods, locomotor time 10.91.02.81.60.41.70.5-0.21.21.30.80.20.60.91.10.7
Rest time, locomotor task time 10.70.81.61.30.40.90.80.41.11.21.00.00.90.80.81.0
Distance moved, locomotor task time 10.30.30.7-0.80.1-0.4-0.7-0.0-0.8-0.7-0.80.0-0.8-0.5-0.4-0.2
Vertical activity count, locomotor time 10.80.81.6-1.20.1-0.5-1.1-0.5-1.2-1.1-1.30.0-1.2-0.8-1.0-0.7
Time >=10cm from walls, locomotor time 20.30.30.60.20.40.50.60.50.40.60.50.20.50.50.80.8
Bouts of movement, locomotor time 20.90.93.80.41.11.50.51.90.60.80.30.50.41.00.91.0
Total resting periods, locomotor time 20.80.93.10.41.01.60.51.80.60.90.30.40.40.90.90.9
Rest time, locomotor task time 21.82.13.51.90.91.51.41.11.81.91.70.61.51.41.21.0
Distance moved, locomotor task time 21.21.43.2-1.50.1-1.1-1.5-0.5-1.8-1.4-1.7-0.1-1.5-1.0-0.50.1
Vertical activity count, locomotor time 23.23.57.0-2.5-0.3-1.4-2.3-1.1-2.6-2.2-2.6-0.4-2.4-1.8-1.5-0.7
Weight adjusted by age0.91.03.01.50.81.70.50.11.01.30.60.50.60.81.30.7
Seeking ratio, delayed vs. immediate footshock0.40.41.20.7-0.5-0.11.00.30.90.51.1-0.11.00.50.2-0.2
Locomotion in novel chamber1.51.93.81.30.80.82.00.71.71.51.91.11.91.21.10.6
Locomotion in novel chamber post-restriction1.01.22.60.30.60.91.61.21.21.11.31.11.51.10.90.8
Progressive ratio2.83.24.31.51.71.31.92.01.81.71.91.71.91.91.82.1
Food seeking constrained by brief footshock0.20.30.60.0-0.50.4-0.8-0.3-0.4-0.2-0.7-0.8-0.7-0.3-0.5-0.5
Seeking ratio, punishment vs. effort2.32.83.9-1.4-1.8-0.9-1.9-1.3-1.8-1.5-1.9-2.0-1.9-1.7-1.6-1.9
Run reversals in cocaine runway, females1.11.12.0-1.3-0.9-1.4-0.8-0.6-1.2-1.2-0.9-1.0-0.9-1.1-1.1-1.2
Run reversals in cocaine runway, males0.10.10.4-0.0-0.00.7-0.60.1-0.3-0.2-0.60.1-0.6-0.30.0-0.0
Latency to leave start box in cocaine runway0.10.10.30.40.40.0-0.20.00.0-0.2-0.00.6-0.10.30.20.5
Latency to leave start box in cocaine runway, F0.10.10.40.00.10.2-0.6-0.2-0.2-0.5-0.50.2-0.6-0.1-0.30.1
Latency to leave start box in cocaine runway, M0.30.30.70.80.4-0.20.60.50.50.40.70.50.70.60.70.6
Cd content in liver1.61.72.8-1.2-1.7-1.5-1.0-1.5-1.2-1.2-1.0-1.6-1.0-1.4-1.1-1.5
Co content in liver0.00.00.30.10.2-0.60.10.1-0.1-0.10.2-0.10.20.1-0.10.0
Cu content in liver0.50.61.5-0.3-0.60.5-1.2-0.8-0.7-0.6-1.2-0.7-1.2-0.7-0.4-0.5
Fe content in liver3.54.28.5-2.0-1.3-0.3-2.8-1.3-2.3-2.3-2.9-1.6-2.9-2.0-1.9-1.1
K content in liver1.01.02.80.71.30.40.60.80.50.90.71.40.70.91.11.7
Mg content in liver1.51.63.51.21.70.41.00.80.81.21.11.81.11.21.51.9
Mn content in liver0.30.40.80.90.50.80.50.50.60.70.50.50.50.60.70.5
Na content in liver2.02.12.71.11.31.11.61.61.51.61.61.31.61.41.61.5
Rb content in liver3.13.97.5-1.8-1.7-2.7-1.9-2.1-2.2-2.2-1.8-1.7-1.9-2.0-1.9-1.3
Se content in liver1.01.22.3-1.2-0.7-0.6-1.5-1.0-1.2-1.2-1.4-0.6-1.5-1.1-1.1-0.7
Sr content in liver1.61.53.30.81.51.51.01.81.11.00.91.41.01.30.91.4
Zn content in liver1.31.55.31.20.92.30.81.31.21.50.70.50.71.21.30.9