| # | tissue | modality | RNA phenotype | h2 | h2 se | h2 P | eQTL R2 | BLUP R2 | ENET R2 | LASSO R2 | eQTL P | BLUP P | ENET P | LASSO P |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Adipose | gene expression | ENSRNOG00000000924 | 0.097 | 0.0980 | 1.4e-06 | 0.022 | 0.034 | 0.021 | 0.025 | 1.7e-03 | 9.4e-05 | 1.8e-03 | 7.4e-04 |
| 2 | Adipose | mRNA stability | ENSRNOG00000000924 | 0.084 | 0.0770 | 1.1e-06 | 0.059 | 0.045 | 0.051 | 0.055 | 4.2e-07 | 9.7e-06 | 2.5e-06 | 9.1e-07 |
| 3 | BLA | gene expression | ENSRNOG00000000924 | 0.152 | 0.0743 | 4.2e-06 | 0.078 | 0.085 | 0.079 | 0.075 | 5.7e-05 | 2.5e-05 | 5.2e-05 | 8.0e-05 |
| 4 | BLA | mRNA stability | ENSRNOG00000000924 | 0.044 | 0.0320 | 3.3e-03 | 0.018 | 0.025 | 0.015 | 0.020 | 3.8e-02 | 1.7e-02 | 5.0e-02 | 2.8e-02 |
| 5 | Brain | mRNA stability | ENSRNOG00000000924 | 0.206 | 0.1019 | 5.3e-15 | 0.155 | 0.160 | 0.165 | 0.164 | 3.0e-14 | 1.1e-14 | 4.3e-15 | 4.7e-15 |
| 6 | IL | mRNA stability | ENSRNOG00000000924 | 0.159 | 0.1060 | 4.3e-03 | 0.045 | 0.071 | 0.030 | 0.055 | 3.1e-02 | 9.0e-03 | 6.6e-02 | 2.0e-02 |
| 7 | LHb | mRNA stability | ENSRNOG00000000924 | 0.170 | 0.1110 | 6.6e-03 | 0.081 | 0.089 | 0.099 | 0.096 | 5.8e-03 | 3.9e-03 | 2.4e-03 | 2.8e-03 |
| 8 | NAcc | gene expression | ENSRNOG00000000924 | 0.037 | 0.0250 | 7.9e-04 | 0.026 | 0.032 | 0.016 | 0.022 | 4.7e-03 | 1.9e-03 | 2.0e-02 | 8.9e-03 |
| 9 | NAcc | mRNA stability | ENSRNOG00000000924 | 0.108 | 0.0665 | 4.5e-08 | 0.118 | 0.100 | 0.102 | 0.107 | 4.2e-09 | 7.4e-08 | 5.3e-08 | 2.3e-08 |
| 10 | OFC | gene expression | ENSRNOG00000000924 | 0.133 | 0.0791 | 9.2e-04 | 0.085 | 0.128 | 0.107 | 0.118 | 4.7e-03 | 6.0e-04 | 1.6e-03 | 1.0e-03 |
| 11 | OFC | mRNA stability | ENSRNOG00000000924 | 0.200 | 0.1452 | 8.0e-04 | 0.149 | 0.147 | 0.166 | 0.180 | 2.2e-04 | 2.4e-04 | 9.4e-05 | 4.8e-05 |
| 12 | PL | gene expression | ENSRNOG00000000924 | 0.085 | 0.0931 | 7.7e-03 | 0.005 | 0.005 | -0.002 | -0.004 | 1.2e-01 | 1.2e-01 | 4.7e-01 | 8.7e-01 |
| 13 | PL | mRNA stability | ENSRNOG00000000924 | 0.126 | 0.0682 | 5.4e-09 | 0.116 | 0.099 | 0.103 | 0.107 | 4.3e-09 | 5.8e-08 | 3.1e-08 | 1.8e-08 |
All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, the gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method.
| Trait | Avg chi2 ratio | Avg chi2 | Max chi2 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 |
|---|
Trait | Avg chi2 ratio | Avg chi2 | Max chi2 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Length with tail | 9.2 | 33.7 | 53.8 | 4.5 | 5.9 | 7.0 | 5.5 | 7.3 | 5.6 | 5.8 | 4.9 | 5.8 | 5.2 | 6.0 | 5.6 | 5.6 |
| Tail length | 8.0 | 24.2 | 33.9 | 4.0 | 5.3 | 4.6 | 5.0 | 5.8 | 4.6 | 4.8 | 4.6 | 5.1 | 4.8 | 5.1 | 4.8 | 5.1 |
| Bone: cortical tissue density | 5.0 | 6.6 | 8.8 | -3.0 | -2.5 | -2.7 | -2.4 | -2.2 | -2.9 | -2.5 | -2.6 | -2.3 | -2.5 | -2.9 | -2.3 | -2.4 |
| Condit. Reinf. active-inactive response ratio | 4.6 | 5.0 | 5.9 | -2.0 | -2.2 | -1.9 | -2.4 | -2.4 | -2.4 | -2.3 | -2.4 | -1.9 | -2.4 | -2.4 | -2.1 | -2.3 |
| Conditioned locomotion | 4.5 | 5.5 | 7.3 | 2.7 | 2.6 | 2.7 | 1.7 | 1.9 | 2.3 | 2.5 | 2.0 | 2.5 | 1.9 | 2.4 | 2.6 | 2.3 |
| Bone: cortical apparent density | 4.5 | 5.8 | 8.3 | -2.9 | -2.3 | -2.6 | -2.2 | -2.0 | -2.8 | -2.3 | -2.5 | -2.1 | -2.3 | -2.7 | -2.2 | -2.2 |
| Short access day 1 total inactive lever presses | 4.2 | 4.6 | 8.2 | 2.1 | 1.2 | 2.9 | 2.2 | 2.6 | 2.5 | 2.5 | 2.1 | 1.0 | 2.1 | 2.1 | 2.2 | 1.6 |
| Intermittent access intake escalation 2 | 4.0 | 3.9 | 5.6 | -2.2 | -1.9 | -2.3 | -1.5 | -1.8 | -2.0 | -2.3 | -1.8 | -1.7 | -1.5 | -2.1 | -2.4 | -2.0 |
| Median of all reaction times | 3.8 | 5.1 | 9.1 | -1.9 | -2.4 | -3.0 | -2.1 | -2.7 | -2.2 | -2.3 | -1.9 | -2.1 | -2.0 | -2.3 | -2.2 | -2.2 |
| Social responses | 3.8 | 4.9 | 6.1 | 2.4 | 2.5 | 1.4 | 2.3 | 2.0 | 2.1 | 2.2 | 2.3 | 2.5 | 2.4 | 2.4 | 2.2 | 2.0 |
| Pavlov. Cond. magazine entry number | 3.8 | 4.8 | 6.6 | -1.8 | -2.5 | -1.1 | -2.3 | -2.2 | -1.9 | -2.1 | -2.3 | -2.6 | -2.3 | -2.2 | -2.2 | -2.6 |
| Fe content in liver | 3.5 | 4.2 | 8.5 | -2.0 | -1.3 | -0.3 | -2.8 | -1.3 | -2.3 | -2.3 | -2.9 | -1.6 | -2.9 | -2.0 | -1.9 | -1.1 |
| Total zone transitions, hab. session 1 | 3.3 | 4.6 | 7.8 | 1.4 | 2.2 | 0.8 | 2.8 | 2.3 | 2.0 | 2.1 | 2.5 | 2.3 | 2.7 | 2.0 | 2.1 | 2.0 |
| Vertical activity count, locomotor time 2 | 3.2 | 3.5 | 7.0 | -2.5 | -0.3 | -1.4 | -2.3 | -1.1 | -2.6 | -2.2 | -2.6 | -0.4 | -2.4 | -1.8 | -1.5 | -0.7 |
| Right kidney weight | 3.1 | 8.8 | 23.3 | 1.8 | 3.3 | 4.8 | 2.0 | 3.7 | 2.5 | 2.9 | 1.6 | 3.3 | 1.7 | 3.0 | 3.1 | 3.3 |
| Rb content in liver | 3.1 | 3.9 | 7.5 | -1.8 | -1.7 | -2.7 | -1.9 | -2.1 | -2.2 | -2.2 | -1.8 | -1.7 | -1.9 | -2.0 | -1.9 | -1.3 |
| Reaction time premature initiation rate | 3.0 | 4.0 | 7.4 | 2.4 | 1.6 | 0.4 | 2.5 | 0.8 | 2.2 | 2.2 | 2.7 | 1.8 | 2.7 | 1.9 | 1.7 | 1.7 |
| Pavlov. Cond. change in total contacts | 2.9 | 3.0 | 4.9 | 2.2 | 2.0 | 1.4 | 1.3 | 1.2 | 1.7 | 1.7 | 1.6 | 2.0 | 1.4 | 1.9 | 1.7 | 2.2 |
| Reaction time premature initiations | 2.8 | 4.0 | 7.1 | 2.0 | 1.7 | 0.6 | 2.6 | 1.2 | 2.1 | 2.3 | 2.6 | 1.9 | 2.7 | 1.9 | 1.8 | 1.6 |
| Progressive ratio | 2.8 | 3.2 | 4.3 | 1.5 | 1.7 | 1.3 | 1.9 | 2.0 | 1.8 | 1.7 | 1.9 | 1.7 | 1.9 | 1.9 | 1.8 | 2.1 |
| Pavlov. Cond. index score | 2.7 | 3.4 | 4.8 | 1.9 | 2.0 | 1.0 | 1.8 | 1.7 | 1.7 | 1.8 | 2.0 | 1.9 | 1.9 | 2.0 | 1.8 | 2.2 |
| Left kidney weight | 2.6 | 7.5 | 15.3 | 1.5 | 2.6 | 3.9 | 2.4 | 3.6 | 2.6 | 2.7 | 2.0 | 2.8 | 2.1 | 2.8 | 2.9 | 2.9 |
| Condit. Reinf. active-inactive response ratio | 2.6 | 2.7 | 3.9 | 2.0 | 1.5 | 1.2 | 1.7 | 1.1 | 1.7 | 1.7 | 1.8 | 1.5 | 1.8 | 1.7 | 1.7 | 1.7 |
| Condit. Reinf. lever reinforcers received | 2.6 | 3.7 | 4.7 | 2.1 | 1.7 | 1.7 | 2.1 | 1.5 | 2.2 | 2.1 | 2.2 | 1.5 | 2.2 | 2.0 | 1.8 | 1.5 |
| Pavlov. Cond. magazine entry latency | 2.6 | 3.4 | 4.5 | 1.5 | 2.0 | 0.8 | 2.1 | 1.8 | 1.6 | 1.8 | 2.0 | 2.1 | 2.1 | 1.9 | 1.8 | 2.0 |
| Pavlov. Cond. response bias | 2.6 | 3.2 | 5.2 | 1.7 | 2.0 | 0.9 | 1.7 | 1.7 | 1.5 | 1.7 | 1.8 | 2.1 | 1.8 | 1.9 | 1.7 | 2.3 |
| Bone: stiffness | 2.6 | 4.2 | 4.8 | 2.0 | 1.9 | 2.1 | 2.0 | 2.2 | 2.1 | 2.2 | 2.0 | 1.9 | 1.9 | 2.2 | 1.9 | 2.1 |
| Bone: trabecular tissue density | 2.6 | 3.7 | 4.9 | 1.9 | 1.9 | 2.1 | 1.6 | 1.5 | 2.0 | 2.2 | 1.8 | 1.9 | 1.7 | 1.9 | 2.1 | 2.0 |
| Liver weight, right | 2.5 | 4.2 | 9.9 | 1.9 | 2.2 | 3.2 | 1.3 | 2.3 | 1.8 | 1.9 | 1.3 | 2.0 | 1.3 | 2.1 | 2.2 | 2.4 |
| Saline control response | 2.5 | 3.3 | 4.9 | 1.6 | 1.8 | 1.2 | 2.2 | 1.7 | 1.7 | 2.0 | 2.0 | 2.0 | 2.2 | 1.7 | 1.9 | 1.3 |
| Reaction time mean AUC | 2.4 | 3.2 | 9.0 | -1.6 | -1.6 | -3.0 | -1.4 | -2.0 | -1.9 | -1.9 | -1.3 | -1.3 | -1.3 | -1.8 | -1.9 | -1.5 |
| Condit. Reinf. active responses | 2.4 | 3.3 | 4.3 | 2.1 | 1.6 | 1.6 | 2.0 | 1.3 | 2.0 | 2.0 | 2.1 | 1.4 | 2.1 | 1.9 | 1.7 | 1.4 |
| Progressive ratio test 1 active lever presses | 2.4 | 2.4 | 4.0 | 1.5 | 1.3 | 1.8 | 1.5 | 1.6 | 1.7 | 1.6 | 1.5 | 1.3 | 1.5 | 1.6 | 2.0 | 1.3 |
| Fecal boli incidents, locomotor time 1 | 2.4 | 2.6 | 7.2 | 2.1 | 1.1 | 2.7 | 1.2 | 1.1 | 2.0 | 1.9 | 1.4 | 1.1 | 1.2 | 1.7 | 1.4 | 1.2 |
| Pavlov. Cond. latency score | 2.3 | 2.9 | 3.8 | 1.8 | 1.7 | 0.8 | 1.7 | 1.5 | 1.6 | 1.7 | 1.9 | 1.7 | 1.9 | 1.8 | 1.7 | 1.9 |
| Seeking ratio, punishment vs. effort | 2.3 | 2.8 | 3.9 | -1.4 | -1.8 | -0.9 | -1.9 | -1.3 | -1.8 | -1.5 | -1.9 | -2.0 | -1.9 | -1.7 | -1.6 | -1.9 |
| Length without tail | 2.2 | 4.8 | 17.8 | 1.3 | 1.9 | 4.2 | 1.4 | 3.2 | 2.1 | 2.2 | 1.1 | 1.9 | 1.2 | 2.1 | 2.1 | 1.7 |
| Locomotion velocity, session 8 | 2.2 | 2.7 | 4.7 | 2.2 | 1.3 | 1.8 | 1.6 | 1.0 | 2.0 | 1.6 | 1.8 | 1.5 | 1.7 | 1.7 | 1.5 | 1.3 |
| Body weight | 2.0 | 8.4 | 26.0 | 1.3 | 2.6 | 5.1 | 2.3 | 4.3 | 2.7 | 2.7 | 1.7 | 2.5 | 1.8 | 2.9 | 2.7 | 2.8 |
| Pavlov. Cond. lever-magazine prob. diff. | 2.0 | 2.5 | 3.9 | 1.6 | 1.8 | 0.8 | 1.5 | 1.5 | 1.5 | 1.5 | 1.7 | 1.7 | 1.6 | 1.7 | 1.5 | 2.0 |
| Bone: apparent density | 2.0 | 3.4 | 7.6 | -2.8 | -1.7 | -0.4 | -1.8 | -0.1 | -1.9 | -1.9 | -2.3 | -1.8 | -2.1 | -1.8 | -2.1 | -1.4 |
| Na content in liver | 2.0 | 2.1 | 2.7 | 1.1 | 1.3 | 1.1 | 1.6 | 1.6 | 1.5 | 1.6 | 1.6 | 1.3 | 1.6 | 1.4 | 1.6 | 1.5 |
| Conditioned reinforcement - actives | 1.9 | 1.8 | 4.3 | 0.9 | 1.4 | 2.0 | 1.0 | 2.1 | 1.2 | 1.3 | 0.9 | 1.3 | 0.9 | 1.3 | 1.3 | 1.3 |
| Stereotopy head waving bouts, day 7 | 1.9 | 2.1 | 2.9 | 1.4 | 1.6 | 0.6 | 1.6 | 1.2 | 1.3 | 1.6 | 1.7 | 1.5 | 1.7 | 1.4 | 1.6 | 1.4 |
| Delta time in closed arm before/after self-admin | 1.9 | 1.8 | 5.0 | 2.1 | 0.5 | 2.2 | 1.1 | 0.8 | 1.8 | 1.6 | 1.3 | 0.5 | 1.1 | 1.5 | 1.1 | 0.9 |
| Mean time between licks in bursts | 1.8 | 2.5 | 4.5 | -2.0 | -1.3 | -2.1 | -1.1 | -1.1 | -1.8 | -1.8 | -1.4 | -1.4 | -1.2 | -1.6 | -1.7 | -1.5 |
| Delay discounting water rate 18 sec | 1.8 | 2.3 | 4.6 | 2.1 | 1.4 | 1.3 | 1.3 | 0.8 | 1.6 | 1.6 | 1.5 | 1.5 | 1.5 | 1.5 | 1.7 | 1.6 |
| Progressive ratio test 1 breakpoint | 1.8 | 1.9 | 3.3 | 1.3 | 1.0 | 1.5 | 1.4 | 1.4 | 1.5 | 1.5 | 1.4 | 1.0 | 1.4 | 1.4 | 1.8 | 1.1 |
| Bone: endosteal perimeter | 1.8 | 3.6 | 6.9 | 1.7 | 2.0 | 2.6 | 1.7 | 2.1 | 2.0 | 1.9 | 1.6 | 1.8 | 1.6 | 2.0 | 1.7 | 1.8 |
| Rest time, locomotor task time 2 | 1.8 | 2.1 | 3.5 | 1.9 | 0.9 | 1.5 | 1.4 | 1.1 | 1.8 | 1.9 | 1.7 | 0.6 | 1.5 | 1.4 | 1.2 | 1.0 |
| Reaction time mean | 1.7 | 2.4 | 7.3 | -1.3 | -1.5 | -2.7 | -1.1 | -1.8 | -1.5 | -1.6 | -1.0 | -1.3 | -1.0 | -1.5 | -1.6 | -1.3 |
| Cocaine response before conditioning | 1.7 | 2.1 | 3.4 | 1.5 | 1.8 | 1.4 | 1.2 | 1.4 | 1.5 | 1.3 | 1.3 | 1.7 | 1.3 | 1.6 | 1.2 | 1.5 |
| Intermittent access day 15 total locomotion | 1.7 | 1.8 | 3.4 | 1.4 | 0.9 | 0.6 | 1.8 | 1.1 | 1.6 | 1.4 | 1.8 | 0.9 | 1.8 | 1.4 | 1.3 | 1.0 |
| Progressive ratio test 1 inactive lever presses | 1.7 | 1.8 | 3.5 | 1.4 | 1.1 | 1.9 | 1.2 | 1.6 | 1.5 | 1.4 | 1.2 | 0.7 | 1.2 | 1.5 | 1.5 | 1.0 |
| Short access day 10 total infusions | 1.7 | 1.9 | 3.1 | 1.4 | 1.1 | 1.5 | 1.2 | 1.4 | 1.5 | 1.4 | 1.3 | 1.0 | 1.3 | 1.5 | 1.8 | 1.1 |
| Locomotion velocity, session 1 | 1.7 | 1.8 | 3.3 | 1.8 | 0.9 | 1.6 | 1.2 | 1.1 | 1.6 | 1.4 | 1.4 | 0.7 | 1.3 | 1.4 | 1.3 | 1.2 |
| Time in closed arm after self-admin | 1.7 | 1.7 | 3.2 | 1.3 | 1.4 | 1.8 | 0.8 | 1.1 | 1.0 | 1.4 | 0.8 | 1.3 | 0.9 | 1.3 | 1.7 | 1.7 |
| Condit. Reinf. inactive responses | 1.6 | 1.9 | 2.5 | 1.6 | 1.3 | 1.6 | 1.1 | 1.2 | 1.5 | 1.5 | 1.3 | 0.8 | 1.2 | 1.4 | 1.4 | 1.6 |
| Time to tail flick, vehicle, after self-admin | 1.6 | 1.7 | 3.5 | 1.0 | 1.7 | 0.9 | 1.2 | 0.9 | 1.2 | 1.1 | 1.2 | 1.9 | 1.2 | 1.4 | 1.5 | 1.5 |
| Cd content in liver | 1.6 | 1.7 | 2.8 | -1.2 | -1.7 | -1.5 | -1.0 | -1.5 | -1.2 | -1.2 | -1.0 | -1.6 | -1.0 | -1.4 | -1.1 | -1.5 |
| Sr content in liver | 1.6 | 1.5 | 3.3 | 0.8 | 1.5 | 1.5 | 1.0 | 1.8 | 1.1 | 1.0 | 0.9 | 1.4 | 1.0 | 1.3 | 0.9 | 1.4 |
| Water consumed over 24 hours | 1.5 | 1.8 | 2.6 | 0.9 | 1.4 | 1.1 | 1.6 | 1.6 | 1.3 | 1.4 | 1.4 | 1.2 | 1.5 | 1.3 | 1.3 | 1.3 |
| Reaction time num false alarms | 1.5 | 2.0 | 2.9 | 1.6 | 1.4 | 1.6 | 1.1 | 1.5 | 1.4 | 1.6 | 1.2 | 1.1 | 1.1 | 1.5 | 1.7 | 1.6 |
| Condit. Reinf. active minus inactive responses | 1.5 | 1.8 | 2.6 | 1.6 | 1.3 | 0.9 | 1.5 | 0.8 | 1.4 | 1.4 | 1.6 | 1.2 | 1.6 | 1.4 | 1.3 | 1.2 |
| Total zone transitions, NPP test | 1.5 | 2.2 | 2.7 | 1.2 | 1.3 | 1.4 | 1.6 | 1.4 | 1.4 | 1.5 | 1.4 | 1.6 | 1.5 | 1.4 | 1.6 | 1.6 |
| Bone volume | 1.5 | 2.5 | 5.4 | -2.3 | -1.1 | -0.1 | -1.8 | -0.1 | -1.7 | -1.7 | -2.2 | -1.3 | -2.1 | -1.5 | -1.8 | -0.9 |
| Delta time in open arm before/after self-admin | 1.5 | 1.4 | 3.8 | -1.1 | -1.4 | -1.9 | -0.5 | -1.3 | -0.9 | -0.7 | -0.5 | -1.6 | -0.5 | -1.3 | -1.1 | -1.6 |
| Time to tail flick, test, before self-admin | 1.5 | 1.5 | 3.3 | 0.5 | 1.8 | 1.3 | 0.8 | 1.1 | 0.7 | 1.2 | 0.7 | 1.8 | 0.7 | 1.2 | 1.6 | 1.5 |
| Locomotion in novel chamber | 1.5 | 1.9 | 3.8 | 1.3 | 0.8 | 0.8 | 2.0 | 0.7 | 1.7 | 1.5 | 1.9 | 1.1 | 1.9 | 1.2 | 1.1 | 0.6 |
| Mg content in liver | 1.5 | 1.6 | 3.5 | 1.2 | 1.7 | 0.4 | 1.0 | 0.8 | 0.8 | 1.2 | 1.1 | 1.8 | 1.1 | 1.2 | 1.5 | 1.9 |
| Delay discounting total patch changes 6 sec | 1.4 | 2.1 | 3.1 | 1.8 | 1.1 | 1.7 | 1.3 | 1.2 | 1.6 | 1.7 | 1.5 | 1.1 | 1.4 | 1.5 | 1.6 | 1.4 |
| Reaction time num false alarms AUC | 1.4 | 2.0 | 2.9 | 1.6 | 1.6 | 1.7 | 0.8 | 1.4 | 1.3 | 1.4 | 1.0 | 1.3 | 0.9 | 1.5 | 1.6 | 1.7 |
| Conditioned locomotion | 1.4 | 1.7 | 2.9 | -1.3 | -1.4 | -1.7 | -1.0 | -0.9 | -1.4 | -1.5 | -1.1 | -1.1 | -1.0 | -1.3 | -1.6 | -1.5 |
| Pavlov. Cond. intertrial magazine entries | 1.4 | 1.8 | 3.2 | 1.6 | 0.6 | 1.2 | 1.7 | 0.7 | 1.8 | 1.6 | 1.8 | 0.7 | 1.8 | 1.3 | 1.3 | 0.5 |
| Intermitt. access day 15 inactive lever presses | 1.4 | 1.6 | 2.9 | 1.7 | 0.7 | 1.7 | 1.0 | 0.4 | 1.6 | 1.6 | 1.3 | 0.6 | 1.1 | 1.3 | 1.5 | 0.9 |
| Intermitt. access escalation Index | 1.4 | 1.3 | 2.1 | -1.4 | -0.7 | -1.5 | -1.0 | -0.6 | -1.4 | -1.2 | -1.2 | -0.8 | -1.1 | -1.1 | -1.2 | -0.9 |
| Intermittent access total locomotion | 1.4 | 1.6 | 3.1 | 1.2 | 1.0 | 0.4 | 1.7 | 0.9 | 1.5 | 1.3 | 1.8 | 0.8 | 1.7 | 1.3 | 1.4 | 0.8 |
| Stereotopy head waving duration, day 7 | 1.3 | 1.6 | 2.1 | 1.4 | 1.3 | 1.1 | 1.2 | 0.9 | 1.3 | 1.4 | 1.3 | 1.1 | 1.3 | 1.3 | 1.4 | 1.1 |
| Time in familiar zone, hab. session 2 | 1.3 | 1.4 | 2.1 | -0.6 | -1.4 | -0.6 | -1.2 | -1.4 | -0.9 | -1.4 | -1.1 | -1.3 | -1.2 | -1.0 | -1.4 | -1.4 |
| Pavlov. Cond. lever contacts | 1.3 | 1.6 | 2.9 | 1.5 | 1.4 | 0.3 | 1.1 | 0.9 | 1.2 | 1.1 | 1.4 | 1.4 | 1.2 | 1.4 | 1.2 | 1.7 |
| Bone: cortical porosity | 1.3 | 1.4 | 3.6 | 1.9 | 0.9 | 1.3 | 0.9 | 0.2 | 1.4 | 1.2 | 1.2 | 1.2 | 1.1 | 1.2 | 1.3 | 1.1 |
| Bone: periosteal perimeter | 1.3 | 2.2 | 5.3 | 1.2 | 1.7 | 2.3 | 1.0 | 1.8 | 1.4 | 1.3 | 1.0 | 1.5 | 1.0 | 1.6 | 1.2 | 1.7 |
| Zn content in liver | 1.3 | 1.5 | 5.3 | 1.2 | 0.9 | 2.3 | 0.8 | 1.3 | 1.2 | 1.5 | 0.7 | 0.5 | 0.7 | 1.2 | 1.3 | 0.9 |
| Number of licking bursts | 1.2 | 1.4 | 2.5 | 0.9 | 1.4 | 1.5 | 0.9 | 1.6 | 1.0 | 1.1 | 0.8 | 1.4 | 0.8 | 1.2 | 1.1 | 1.4 |
| Condit. Reinf. lever presses | 1.2 | 1.6 | 2.7 | 1.2 | 1.6 | 1.2 | 1.1 | 1.1 | 1.3 | 1.3 | 1.2 | 1.6 | 1.2 | 1.4 | 1.2 | 1.2 |
| Progressive ratio test 2 inactive lever presses | 1.2 | 1.4 | 4.0 | 0.0 | 0.6 | 0.8 | 1.8 | 2.0 | 1.2 | 1.2 | 1.4 | 0.3 | 1.5 | 1.0 | 1.1 | 0.6 |
| Bone: cortical porosity | 1.2 | 1.3 | 2.9 | 1.7 | 0.9 | 1.3 | 0.8 | 0.4 | 1.3 | 1.1 | 1.1 | 1.2 | 0.9 | 1.2 | 1.1 | 1.0 |
| Bone: trabecular number | 1.2 | 1.9 | 4.8 | -2.2 | -1.2 | -0.5 | -1.2 | 0.3 | -1.5 | -1.5 | -1.7 | -1.3 | -1.4 | -1.3 | -1.7 | -1.0 |
| Distance moved, locomotor task time 2 | 1.2 | 1.4 | 3.2 | -1.5 | 0.1 | -1.1 | -1.5 | -0.5 | -1.8 | -1.4 | -1.7 | -0.1 | -1.5 | -1.0 | -0.5 | 0.1 |
| Reaction time mean minus median | 1.1 | 1.4 | 2.8 | 0.5 | 1.5 | -0.9 | 1.4 | 1.3 | 0.6 | 0.5 | 1.3 | 1.7 | 1.4 | 1.0 | 0.6 | 1.7 |
| Locomotion velocity, session 3 | 1.1 | 1.2 | 3.1 | 1.6 | 1.0 | 1.8 | 0.5 | 0.7 | 1.2 | 1.2 | 0.8 | 0.6 | 0.6 | 1.1 | 1.2 | 1.2 |
| Locomotion distance, session 3 | 1.1 | 1.2 | 2.0 | 0.9 | 0.9 | 0.8 | 1.2 | 1.1 | 1.1 | 1.4 | 1.2 | 0.4 | 1.2 | 1.0 | 1.4 | 1.0 |
| Bone: trabecular thickness | 1.1 | 1.3 | 3.2 | -1.8 | -0.9 | 0.0 | -1.3 | -0.3 | -1.3 | -1.0 | -1.6 | -0.9 | -1.5 | -1.2 | -1.1 | -0.7 |
| Run reversals in cocaine runway, females | 1.1 | 1.1 | 2.0 | -1.3 | -0.9 | -1.4 | -0.8 | -0.6 | -1.2 | -1.2 | -0.9 | -1.0 | -0.9 | -1.1 | -1.1 | -1.2 |
| Delay discounting total patch changes 24 sec | 1.0 | 1.3 | 2.8 | 1.7 | 0.8 | 1.6 | 0.8 | 0.7 | 1.4 | 1.2 | 1.1 | 0.5 | 0.9 | 1.2 | 1.3 | 1.1 |
| Locomotor activity | 1.0 | 1.6 | 3.2 | 1.2 | 1.2 | 1.8 | 1.0 | 1.7 | 1.3 | 1.3 | 1.0 | 0.9 | 1.0 | 1.2 | 1.2 | 1.3 |
| Reaction time mean minus median AUC | 1.0 | 1.3 | 2.4 | 0.5 | 1.3 | -1.0 | 1.5 | 1.2 | 0.5 | 0.7 | 1.3 | 1.6 | 1.5 | 0.9 | 0.8 | 1.4 |
| Condit. Reinf. inactive responses | 1.0 | 1.2 | 1.9 | 1.1 | 0.7 | 1.2 | 1.3 | 0.9 | 1.3 | 1.4 | 1.3 | 0.7 | 1.3 | 1.1 | 1.1 | 0.5 |
| Intermittent access intake escalation | 1.0 | 1.0 | 2.0 | -1.3 | -0.9 | -1.2 | -0.6 | -0.7 | -1.0 | -1.2 | -0.9 | -0.7 | -0.7 | -1.1 | -1.4 | -0.9 |
| Pavlov. Cond. lever latency | 1.0 | 1.3 | 2.5 | -1.5 | -1.2 | -0.2 | -1.0 | -0.8 | -1.1 | -1.0 | -1.3 | -1.1 | -1.2 | -1.3 | -1.0 | -1.6 |
| Bone: elastic displacement | 1.0 | 1.1 | 2.5 | -1.1 | -1.6 | -1.0 | -0.6 | -1.0 | -0.9 | -0.9 | -0.8 | -1.4 | -0.7 | -1.2 | -0.7 | -1.4 |
| Time in open arm after self-admin | 1.0 | 1.1 | 2.0 | -1.0 | -1.1 | -1.4 | -0.7 | -0.6 | -0.9 | -1.0 | -0.7 | -1.3 | -0.7 | -1.0 | -1.3 | -1.4 |
| Delay disc. indifference point, 24s delay | 1.0 | 1.0 | 2.3 | 1.5 | 0.7 | 1.2 | 0.7 | 0.3 | 1.2 | 1.0 | 1.0 | 1.1 | 0.8 | 1.1 | 0.8 | 0.9 |
| Locomotion in novel chamber post-restriction | 1.0 | 1.2 | 2.6 | 0.3 | 0.6 | 0.9 | 1.6 | 1.2 | 1.2 | 1.1 | 1.3 | 1.1 | 1.5 | 1.1 | 0.9 | 0.8 |
| K content in liver | 1.0 | 1.0 | 2.8 | 0.7 | 1.3 | 0.4 | 0.6 | 0.8 | 0.5 | 0.9 | 0.7 | 1.4 | 0.7 | 0.9 | 1.1 | 1.7 |
| Se content in liver | 1.0 | 1.2 | 2.3 | -1.2 | -0.7 | -0.6 | -1.5 | -1.0 | -1.2 | -1.2 | -1.4 | -0.6 | -1.5 | -1.1 | -1.1 | -0.7 |
| Times rat made contact with spout | 0.9 | 1.0 | 1.4 | 1.2 | 0.9 | 0.9 | 1.0 | 0.8 | 1.0 | 1.0 | 1.0 | 0.9 | 1.1 | 1.0 | 1.1 | 1.1 |
| Cocaine response after cond. corrected | 0.9 | 1.0 | 1.5 | -1.2 | -0.9 | -1.2 | -1.0 | -0.8 | -1.0 | -1.1 | -0.9 | -0.5 | -1.1 | -1.1 | -0.9 | -0.9 |
| Intermittent access intake day 1-15 change | 0.9 | 0.9 | 1.9 | -1.2 | -0.8 | -1.2 | -0.6 | -0.7 | -1.0 | -1.2 | -0.9 | -0.6 | -0.6 | -1.0 | -1.4 | -0.8 |
| Total locomotion distance, NPP test | 0.9 | 1.2 | 1.8 | 0.8 | 1.1 | 0.4 | 1.3 | 1.0 | 1.0 | 1.1 | 1.2 | 1.2 | 1.3 | 1.1 | 1.2 | 1.3 |
| Pavlov. Cond. intertrial magazine entries | 0.9 | 1.0 | 2.6 | -0.8 | -1.2 | -0.7 | -1.0 | -0.9 | -0.9 | -0.7 | -1.0 | -1.6 | -1.0 | -1.1 | -0.8 | -1.2 |
| Bone: endosteal estimation | 0.9 | 1.9 | 2.8 | 1.0 | 1.0 | 1.6 | 1.7 | 1.6 | 1.5 | 1.5 | 1.4 | 1.2 | 1.5 | 1.3 | 1.3 | 1.0 |
| Area under the delay curve | 0.9 | 1.0 | 1.9 | 1.4 | 0.7 | 0.6 | 1.1 | 0.4 | 1.3 | 0.8 | 1.3 | 1.1 | 1.2 | 1.2 | 0.6 | 0.9 |
| Total resting periods, locomotor time 1 | 0.9 | 1.0 | 2.8 | 1.6 | 0.4 | 1.7 | 0.5 | -0.2 | 1.2 | 1.3 | 0.8 | 0.2 | 0.6 | 0.9 | 1.1 | 0.7 |
| Bouts of movement, locomotor time 2 | 0.9 | 0.9 | 3.8 | 0.4 | 1.1 | 1.5 | 0.5 | 1.9 | 0.6 | 0.8 | 0.3 | 0.5 | 0.4 | 1.0 | 0.9 | 1.0 |
| Weight adjusted by age | 0.9 | 1.0 | 3.0 | 1.5 | 0.8 | 1.7 | 0.5 | 0.1 | 1.0 | 1.3 | 0.6 | 0.5 | 0.6 | 0.8 | 1.3 | 0.7 |
| Food consumed during 24 hour testing period | 0.8 | 1.0 | 1.5 | 1.2 | 0.7 | 0.5 | 1.1 | 0.3 | 1.1 | 1.2 | 1.2 | 0.7 | 1.2 | 1.0 | 1.2 | 0.8 |
| Reaction time false alarm rate | 0.8 | 1.1 | 2.1 | 1.4 | 1.1 | 1.4 | 0.4 | 0.9 | 1.0 | 1.0 | 0.7 | 0.8 | 0.6 | 1.1 | 1.2 | 1.5 |
| Short access total locomotion | 0.8 | 0.8 | 2.6 | 1.6 | 0.6 | 1.1 | 0.6 | 0.1 | 1.0 | 1.1 | 0.8 | 0.4 | 0.7 | 1.0 | 1.2 | 0.5 |
| Locomotion distance, session 8 | 0.8 | 1.2 | 1.8 | 1.0 | 1.1 | 1.4 | 1.1 | 1.3 | 1.1 | 0.8 | 1.0 | 0.8 | 1.0 | 1.2 | 0.9 | 1.2 |
| Degree of sensitization stereotypy | 0.8 | 0.9 | 1.4 | 0.8 | 1.2 | 0.5 | 1.0 | 0.7 | 0.9 | 1.1 | 1.0 | 0.8 | 1.0 | 0.9 | 1.2 | 0.8 |
| Locomotion velocity, NPP test | 0.8 | 1.1 | 1.8 | 0.6 | 1.1 | 0.1 | 1.3 | 1.1 | 0.8 | 1.0 | 1.2 | 1.2 | 1.3 | 1.0 | 1.1 | 1.3 |
| Bone: connectivity density | 0.8 | 1.3 | 4.5 | -2.1 | -0.9 | -0.3 | -0.7 | 0.7 | -1.2 | -1.2 | -1.4 | -1.0 | -1.1 | -1.0 | -1.4 | -0.6 |
| Bone: marrow area | 0.8 | 1.8 | 2.8 | 0.9 | 0.9 | 1.5 | 1.7 | 1.6 | 1.5 | 1.4 | 1.4 | 1.1 | 1.5 | 1.3 | 1.2 | 1.0 |
| Bone: maximum force | 0.8 | 1.4 | 2.6 | 0.8 | 1.2 | 1.4 | 1.0 | 1.6 | 1.0 | 1.1 | 0.9 | 1.3 | 0.9 | 1.2 | 1.1 | 1.4 |
| Bone: tissue strength | 0.8 | 0.8 | 1.2 | -1.1 | -0.8 | -0.5 | -0.9 | -0.6 | -1.0 | -1.0 | -1.1 | -0.6 | -1.0 | -0.9 | -0.8 | -0.9 |
| Breakpoint value in progressive ratio session | 0.8 | 0.9 | 3.0 | 0.0 | 1.4 | 0.0 | 0.8 | 1.7 | 0.3 | 0.4 | 0.6 | 1.1 | 0.7 | 0.8 | 0.6 | 1.4 |
| Delay discount exponential model param | 0.8 | 0.8 | 1.6 | -1.3 | -0.6 | -0.4 | -1.0 | -0.3 | -1.2 | -0.7 | -1.2 | -1.0 | -1.1 | -1.1 | -0.4 | -0.7 |
| Vertical activity count, locomotor time 1 | 0.8 | 0.8 | 1.6 | -1.2 | 0.1 | -0.5 | -1.1 | -0.5 | -1.2 | -1.1 | -1.3 | 0.0 | -1.2 | -0.8 | -1.0 | -0.7 |
| Total resting periods, locomotor time 2 | 0.8 | 0.9 | 3.1 | 0.4 | 1.0 | 1.6 | 0.5 | 1.8 | 0.6 | 0.9 | 0.3 | 0.4 | 0.4 | 0.9 | 0.9 | 0.9 |
| BMI with tail | 0.7 | 2.3 | 3.6 | -1.7 | -1.8 | -0.1 | -1.7 | -1.3 | -1.2 | -1.5 | -1.8 | -1.9 | -1.8 | -1.4 | -1.3 | -1.3 |
| Glucose | 0.7 | 1.0 | 3.9 | 1.4 | 0.1 | 2.0 | 0.7 | 0.5 | 1.4 | 1.1 | 0.9 | 0.5 | 0.7 | 1.0 | 0.9 | 0.4 |
| Tibia length | 0.7 | 1.9 | 6.9 | 0.4 | 1.5 | 1.6 | 1.5 | 2.6 | 1.2 | 1.2 | 1.1 | 1.3 | 1.3 | 1.3 | 0.8 | 0.9 |
| Delay discounting time to switch 0 sec | 0.7 | 1.1 | 2.6 | -1.2 | -0.4 | -1.6 | -1.0 | -0.9 | -1.2 | -1.2 | -1.0 | -0.2 | -1.0 | -0.9 | -1.2 | -0.7 |
| Locomotor testing rearing | 0.7 | 1.1 | 1.4 | -1.1 | -0.8 | -1.1 | -1.0 | -1.0 | -1.2 | -0.9 | -1.1 | -1.1 | -1.0 | -1.2 | -0.9 | -0.9 |
| Incentive Sensitization - Responses | 0.7 | 0.7 | 2.3 | -1.3 | -0.5 | -0.7 | 1.3 | 1.5 | 0.2 | 0.1 | 0.7 | -0.7 | 1.0 | -0.1 | -0.4 | -0.5 |
| Incentive Sensitization - Breakpoint | 0.7 | 0.7 | 2.4 | -1.3 | -0.5 | -0.7 | 1.3 | 1.5 | 0.2 | 0.1 | 0.7 | -0.6 | 1.0 | -0.1 | -0.4 | -0.4 |
| Total sessions with >9 infusions | 0.7 | 0.8 | 1.6 | 0.9 | 0.6 | 1.3 | 0.8 | 0.7 | 1.0 | 1.0 | 0.7 | 0.6 | 0.8 | 1.0 | 1.2 | 0.7 |
| Locomotion distance, session 2 | 0.7 | 1.0 | 2.4 | 0.7 | 0.2 | 0.8 | 1.5 | 1.2 | 1.2 | 1.0 | 1.3 | 0.2 | 1.4 | 0.9 | 0.8 | 0.7 |
| Degree of sensitization distance | 0.7 | 0.7 | 2.1 | -0.6 | -0.7 | -1.3 | -0.6 | -0.8 | -0.6 | -1.4 | -0.5 | -0.3 | -0.5 | -0.6 | -1.5 | -0.7 |
| Condit. Reinf. active minus inactive responses | 0.7 | 0.8 | 1.4 | -0.7 | -0.7 | -0.2 | -1.1 | -0.9 | -1.0 | -0.9 | -1.2 | -0.4 | -1.1 | -0.9 | -0.8 | -0.8 |
| Bone surface | 0.7 | 1.2 | 3.8 | -1.9 | -0.6 | 0.2 | -1.0 | 0.6 | -1.1 | -1.2 | -1.5 | -0.9 | -1.3 | -1.0 | -1.3 | -0.5 |
| Bone: cortical thickness | 0.7 | 1.2 | 3.4 | -1.8 | -0.3 | -0.5 | -1.2 | 0.2 | -1.5 | -1.3 | -1.6 | -0.4 | -1.4 | -1.0 | -1.0 | -0.1 |
| Bone: periosteal estimation | 0.7 | 1.3 | 3.4 | 0.4 | 1.3 | 1.6 | 1.0 | 1.8 | 1.0 | 1.0 | 0.7 | 1.2 | 0.8 | 1.1 | 0.9 | 1.4 |
| Ambulatory time after self-admin | 0.7 | 0.8 | 2.0 | 1.4 | 1.0 | 1.1 | -0.0 | -0.1 | 0.6 | 0.7 | 0.4 | 1.3 | 0.2 | 0.8 | 1.2 | 1.1 |
| Delay disc. indifference point, 16s delay | 0.7 | 0.7 | 1.6 | 1.3 | 0.3 | 1.0 | 0.6 | -0.2 | 1.1 | 0.8 | 0.8 | 0.9 | 0.7 | 0.8 | 0.6 | 0.9 |
| Delay discount hyperbolic model param | 0.7 | 0.7 | 1.4 | -1.2 | -0.6 | -0.3 | -1.0 | -0.3 | -1.1 | -0.5 | -1.2 | -1.0 | -1.1 | -1.0 | -0.3 | -0.7 |
| Rest time, locomotor task time 1 | 0.7 | 0.8 | 1.6 | 1.3 | 0.4 | 0.9 | 0.8 | 0.4 | 1.1 | 1.2 | 1.0 | 0.0 | 0.9 | 0.8 | 0.8 | 1.0 |
| BMI without tail | 0.6 | 1.2 | 2.2 | 0.5 | 1.2 | 0.8 | 1.2 | 1.3 | 1.0 | 0.9 | 1.0 | 1.0 | 1.1 | 1.1 | 1.1 | 1.5 |
| Intraocular pressure | 0.6 | 0.9 | 1.7 | -1.3 | -0.4 | -1.1 | -0.9 | -0.1 | -1.2 | -1.3 | -1.1 | -0.6 | -1.0 | -0.9 | -1.2 | -0.7 |
| Mean num. licks in bursts | 0.6 | 0.7 | 1.8 | -0.3 | -1.1 | -1.1 | -0.5 | -1.4 | -0.6 | -0.7 | -0.4 | -1.1 | -0.4 | -0.8 | -0.6 | -1.0 |
| Delay discounting total patch changes 12 sec | 0.6 | 0.8 | 3.2 | 1.4 | 0.2 | 1.8 | 0.3 | 0.5 | 1.1 | 1.0 | 0.6 | 0.0 | 0.4 | 0.8 | 1.0 | 0.7 |
| Delay discounting total patch changes 18 sec | 0.6 | 0.9 | 1.7 | -0.5 | -1.0 | -0.4 | -1.3 | -1.0 | -1.0 | -0.8 | -1.1 | -1.0 | -1.2 | -1.0 | -0.5 | -0.7 |
| Cocaine response after cond. not corrected | 0.6 | 0.6 | 1.1 | -1.0 | -0.4 | -1.0 | -0.9 | -0.5 | -0.9 | -1.0 | -0.8 | -0.1 | -0.9 | -0.8 | -0.8 | -0.6 |
| Post-drug Anxiety | 0.6 | 0.7 | 3.2 | -1.3 | -0.6 | -1.8 | -0.2 | -0.3 | -0.9 | -0.8 | -0.4 | -0.8 | -0.3 | -0.8 | -0.3 | -0.4 |
| Progressive ratio test 2 active lever presses | 0.6 | 0.6 | 2.5 | -0.8 | 0.0 | -0.2 | 1.5 | 1.6 | 0.5 | 0.4 | 0.9 | -0.0 | 1.2 | 0.3 | 0.4 | -0.0 |
| Progressive ratio test 2 breakpoint | 0.6 | 0.7 | 3.0 | -0.6 | 0.1 | -0.1 | 1.5 | 1.7 | 0.6 | 0.4 | 1.0 | 0.1 | 1.3 | 0.5 | 0.4 | 0.1 |
| One hour access (shock baseline) | 0.6 | 0.7 | 1.6 | 0.2 | 0.6 | 0.3 | 1.1 | 1.3 | 0.8 | 0.7 | 0.9 | 0.3 | 1.0 | 0.7 | 1.0 | 0.8 |
| Context. condit. distance diff. score | 0.6 | 0.7 | 1.5 | 0.9 | 1.2 | 1.2 | 0.3 | 0.8 | 0.7 | 0.5 | 0.4 | 1.1 | 0.4 | 0.9 | 0.6 | 1.1 |
| Locomotion velocity, session 7 | 0.6 | 0.6 | 1.9 | 1.4 | 1.0 | 0.5 | 0.5 | 0.3 | 0.9 | 0.3 | 0.8 | 0.8 | 0.6 | 1.0 | 0.3 | 1.0 |
| Change in fecal boli incidents, locomotor task | 0.6 | 0.6 | 1.8 | -0.8 | -0.5 | -1.3 | -0.3 | -0.7 | -0.6 | -0.8 | -0.3 | -0.8 | -0.3 | -0.8 | -1.0 | -1.1 |
| Time >=10cm from walls, locomotor time 1 | 0.6 | 0.6 | 1.7 | -1.2 | -1.3 | -0.9 | 0.1 | -0.3 | -0.4 | -0.5 | -0.1 | -1.2 | -0.0 | -0.7 | -0.4 | -0.8 |
| Epididymis fat weight | 0.5 | 1.1 | 2.8 | -1.2 | -0.5 | 0.5 | -1.5 | -0.2 | -1.0 | -1.2 | -1.6 | -0.5 | -1.7 | -0.8 | -1.0 | -0.3 |
| Heart weight | 0.5 | 0.8 | 2.1 | -0.1 | 0.7 | 0.2 | 1.5 | 1.4 | 0.8 | 0.7 | 1.1 | 0.5 | 1.3 | 0.7 | 0.6 | 0.3 |
| Delay discounting total patch changes 0 sec | 0.5 | 0.7 | 1.9 | 1.1 | 0.7 | 1.4 | 0.4 | 0.7 | 0.8 | 1.1 | 0.6 | 0.5 | 0.5 | 0.8 | 1.1 | 0.9 |
| Reaction time omissions | 0.5 | 0.6 | 2.9 | -0.9 | -0.5 | -1.7 | -0.4 | -0.4 | -1.0 | -0.8 | -0.5 | -0.3 | -0.4 | -0.7 | -1.0 | -0.7 |
| Intermittent access day 1 total infusions | 0.5 | 0.6 | 1.6 | 0.1 | 0.2 | 0.0 | 1.0 | 1.3 | 0.6 | 0.7 | 0.9 | -0.0 | 0.9 | 0.6 | 1.1 | 0.5 |
| Compulsive drug intake | 0.5 | 0.5 | 1.4 | 0.1 | -1.0 | -0.5 | -0.4 | -1.2 | -0.2 | -0.4 | -0.2 | -0.8 | -0.3 | -0.6 | -1.1 | -1.1 |
| Bone: maximum diameter | 0.5 | 1.0 | 3.0 | 0.2 | 1.3 | 1.7 | 0.5 | 1.5 | 0.6 | 0.8 | 0.2 | 1.1 | 0.4 | 0.9 | 0.8 | 1.2 |
| Bone: maximum moment | 0.5 | 0.8 | 1.9 | 0.5 | 1.0 | 1.2 | 0.7 | 1.4 | 0.7 | 0.8 | 0.6 | 1.1 | 0.6 | 1.0 | 0.8 | 1.2 |
| Bouts of movement, locomotor time 1 | 0.5 | 0.6 | 1.9 | 1.3 | 0.3 | 1.4 | 0.3 | -0.2 | 0.9 | 1.0 | 0.5 | 0.2 | 0.4 | 0.6 | 1.0 | 0.4 |
| Cu content in liver | 0.5 | 0.6 | 1.5 | -0.3 | -0.6 | 0.5 | -1.2 | -0.8 | -0.7 | -0.6 | -1.2 | -0.7 | -1.2 | -0.7 | -0.4 | -0.5 |
| Extensor digitorum longus weight | 0.4 | 1.6 | 4.3 | 0.9 | 1.8 | 2.1 | 0.4 | 1.7 | 0.8 | 0.7 | 0.3 | 1.8 | 0.4 | 1.3 | 0.8 | 1.5 |
| Std. dev. time between licks in bursts | 0.4 | 0.5 | 0.9 | 0.5 | 0.4 | 0.6 | 0.9 | 0.7 | 0.9 | 0.6 | 0.9 | 0.5 | 0.9 | 0.8 | 0.4 | 0.2 |
| Indifference point 0 sec | 0.4 | 0.7 | 2.1 | 1.0 | 0.6 | 1.4 | 0.4 | 0.7 | 0.8 | 1.0 | 0.5 | 0.4 | 0.4 | 0.7 | 1.0 | 0.8 |
| Indifference point AUC | 0.4 | 0.5 | 1.4 | 0.9 | 0.3 | 1.2 | 0.6 | 0.6 | 0.9 | 0.6 | 0.6 | 0.1 | 0.6 | 0.7 | 0.7 | 0.5 |
| Delay discounting water rate 24 sec | 0.4 | 0.5 | 1.5 | -1.2 | -0.9 | -1.0 | 0.1 | -0.1 | -0.8 | -0.5 | -0.4 | -0.8 | -0.1 | -0.8 | -0.5 | -0.8 |
| Light reinforcement 1 | 0.4 | 0.7 | 2.3 | 1.5 | 0.7 | 0.9 | 0.2 | -0.1 | 0.9 | 0.7 | 0.7 | 0.8 | 0.4 | 1.0 | 0.7 | 0.9 |
| Pavlov. Cond. lever latency | 0.4 | 0.5 | 0.8 | -0.9 | -0.8 | -0.4 | -0.7 | -0.3 | -0.9 | -0.5 | -0.9 | -0.9 | -0.8 | -0.8 | -0.4 | -0.4 |
| Pavlov. Cond. lever-magazine prob. diff. | 0.4 | 0.5 | 0.8 | 0.6 | 0.9 | 0.4 | 0.8 | 0.8 | 0.7 | 0.4 | 0.8 | 0.9 | 0.8 | 0.9 | 0.3 | 0.5 |
| Intermitt. access day 1 inactive lever presses | 0.4 | 0.4 | 1.2 | 0.9 | 0.1 | 1.1 | 0.4 | 0.1 | 0.8 | 0.9 | 0.5 | -0.0 | 0.4 | 0.6 | 0.9 | 0.4 |
| Number of responses in last shaping day | 0.4 | 0.4 | 1.2 | 0.1 | -0.1 | -0.1 | -1.1 | -1.1 | -0.7 | -0.5 | -0.8 | -0.0 | -0.9 | -0.4 | -0.1 | -0.0 |
| Condit. Reinf. lever presses | 0.4 | 0.5 | 1.2 | 0.7 | 1.0 | 0.7 | 0.3 | 0.7 | 0.6 | 0.6 | 0.4 | 0.8 | 0.3 | 0.8 | 0.6 | 1.1 |
| Time in familiar zone, hab. session 1 | 0.4 | 0.4 | 0.6 | -0.7 | -0.6 | -0.3 | -0.6 | -0.8 | -0.6 | -0.6 | -0.6 | -0.4 | -0.6 | -0.6 | -0.6 | -0.8 |
| Time in novel zone, hab. session 2 | 0.4 | 0.4 | 0.7 | 0.4 | 0.7 | 0.3 | 0.7 | 0.8 | 0.5 | 0.8 | 0.6 | 0.5 | 0.7 | 0.6 | 0.8 | 0.9 |
| Bone: cortical area | 0.4 | 0.6 | 1.9 | -0.2 | 1.1 | 1.3 | 0.0 | 1.4 | 0.2 | 0.3 | -0.2 | 0.8 | -0.1 | 0.5 | 0.4 | 1.1 |
| Bone: cortical thickness | 0.4 | 0.4 | 2.4 | -1.0 | -0.7 | -1.6 | 0.1 | -0.2 | -0.7 | -0.5 | -0.2 | -0.3 | 0.0 | -0.7 | -0.4 | -0.4 |
| Bone: final force | 0.4 | 0.7 | 1.1 | 0.6 | 0.7 | 1.0 | 0.8 | 1.0 | 0.8 | 0.8 | 0.7 | 0.9 | 0.7 | 0.9 | 0.8 | 1.0 |
| Bone: minimum diameter | 0.4 | 0.8 | 1.2 | 0.9 | 1.1 | 1.1 | 0.6 | 0.9 | 0.9 | 0.8 | 0.7 | 0.9 | 0.6 | 1.0 | 0.7 | 1.1 |
| Distance traveled after self-admin | 0.4 | 0.4 | 1.1 | 1.0 | 0.9 | 0.7 | -0.1 | -0.2 | 0.4 | 0.5 | 0.2 | 1.0 | 0.1 | 0.6 | 0.9 | 0.7 |
| Active lever presses in extinction session 6 | 0.4 | 0.3 | 0.9 | -0.8 | 0.0 | 0.0 | -0.8 | 0.1 | -0.7 | -0.7 | -0.9 | 0.4 | -0.9 | -0.4 | -0.5 | 0.1 |
| Delay disc. indifference point, 2s delay | 0.4 | 0.4 | 1.1 | 0.5 | 0.4 | -0.5 | 1.0 | 0.4 | 0.7 | 0.1 | 1.0 | 0.6 | 1.0 | 0.7 | -0.1 | 0.3 |
| Seeking ratio, delayed vs. immediate footshock | 0.4 | 0.4 | 1.2 | 0.7 | -0.5 | -0.1 | 1.0 | 0.3 | 0.9 | 0.5 | 1.1 | -0.1 | 1.0 | 0.5 | 0.2 | -0.2 |
| Liver weight, left | 0.3 | 0.5 | 2.1 | -0.0 | 0.9 | 1.2 | -0.3 | 1.0 | -0.1 | 0.1 | -0.4 | 0.9 | -0.3 | 0.3 | 0.5 | 1.5 |
| Soleus weight | 0.3 | 0.9 | 3.2 | 0.1 | 1.6 | 1.0 | 0.0 | 1.2 | 0.1 | 0.2 | -0.1 | 1.8 | -0.0 | 0.7 | 0.5 | 1.7 |
| Delay discounting water rate 12 sec | 0.3 | 0.4 | 1.0 | 0.2 | 0.5 | 0.8 | 0.6 | 0.7 | 0.4 | 0.8 | 0.3 | 0.8 | 0.5 | 0.4 | 1.0 | 0.6 |
| Light reinforcement 2 | 0.3 | 0.3 | 1.2 | 1.1 | 0.3 | 1.1 | -0.8 | -0.6 | 0.2 | 0.1 | -0.4 | 0.3 | -0.6 | 0.4 | 0.1 | 0.2 |
| Reaction time number correct | 0.3 | 0.4 | 1.0 | 0.0 | 0.6 | 0.7 | 0.7 | 1.0 | 0.4 | 0.7 | 0.4 | 0.8 | 0.6 | 0.5 | 0.6 | 0.2 |
| Reaction time trials correct on left | 0.3 | 0.4 | 1.0 | 0.0 | 0.6 | 0.7 | 0.7 | 1.0 | 0.4 | 0.7 | 0.4 | 0.8 | 0.6 | 0.5 | 0.6 | 0.2 |
| Reaction time trials on left | 0.3 | 0.4 | 1.0 | 0.0 | 0.6 | 0.7 | 0.7 | 1.0 | 0.4 | 0.7 | 0.4 | 0.8 | 0.6 | 0.5 | 0.6 | 0.2 |
| Std. dev. reaction times | 0.3 | 0.5 | 2.5 | -0.2 | 0.7 | -1.6 | 0.7 | 0.5 | -0.2 | -0.1 | 0.6 | 0.8 | 0.7 | 0.2 | -0.1 | 0.8 |
| Reaction time trials completed | 0.3 | 0.4 | 1.0 | 0.0 | 0.6 | 0.7 | 0.7 | 1.0 | 0.4 | 0.7 | 0.4 | 0.8 | 0.6 | 0.5 | 0.6 | 0.2 |
| Pavlov. Cond. magazine entry latency | 0.3 | 0.3 | 0.7 | -0.7 | 0.2 | -0.7 | -0.4 | 0.4 | -0.6 | -0.8 | -0.5 | -0.1 | -0.4 | -0.3 | -0.9 | -0.3 |
| Pavlov. Cond. change in total contacts | 0.3 | 0.4 | 0.5 | 0.6 | 0.7 | 0.6 | 0.7 | 0.4 | 0.7 | 0.6 | 0.7 | 0.7 | 0.7 | 0.7 | 0.5 | 0.4 |
| Pavlov. Cond. index score | 0.3 | 0.4 | 0.7 | 0.6 | 0.8 | 0.3 | 0.8 | 0.8 | 0.7 | 0.4 | 0.8 | 0.8 | 0.8 | 0.8 | 0.3 | 0.4 |
| Pavlov. Cond. latency score | 0.3 | 0.4 | 0.7 | 0.5 | 0.8 | 0.3 | 0.7 | 0.7 | 0.6 | 0.4 | 0.7 | 0.8 | 0.7 | 0.7 | 0.3 | 0.4 |
| Conditioned reinforcement - inactives | 0.3 | 0.4 | 1.6 | 0.5 | 0.1 | 1.3 | 0.4 | 0.8 | 0.8 | 0.7 | 0.4 | -0.3 | 0.4 | 0.5 | 0.7 | 0.1 |
| Intermittent access total infusions | 0.3 | 0.4 | 1.0 | -0.1 | 0.1 | -0.4 | 1.0 | 0.9 | 0.5 | 0.5 | 0.8 | -0.1 | 0.9 | 0.4 | 0.7 | 0.2 |
| Intermittent access day 1 locomotion | 0.3 | 0.3 | 0.7 | 0.5 | 0.0 | 0.1 | 0.6 | 0.2 | 0.5 | 0.7 | 0.7 | -0.1 | 0.7 | 0.4 | 0.9 | 0.0 |
| Lifetime Intake | 0.3 | 0.3 | 0.8 | -0.0 | -0.1 | -0.0 | 0.9 | 0.8 | 0.6 | 0.5 | 0.7 | -0.3 | 0.8 | 0.4 | 0.7 | 0.1 |
| Short access day 10 total inactive lever presses | 0.3 | 0.3 | 0.6 | 0.6 | 0.3 | 0.2 | 0.7 | 0.4 | 0.6 | 0.7 | 0.8 | -0.3 | 0.8 | 0.5 | 0.7 | 0.4 |
| Short access total infusions | 0.3 | 0.4 | 0.9 | 0.5 | -0.1 | 0.8 | 0.6 | 0.8 | 0.8 | 0.7 | 0.6 | -0.2 | 0.6 | 0.6 | 0.9 | 0.1 |
| Short access day 1 locomotion | 0.3 | 0.3 | 0.9 | 0.9 | 0.5 | 0.9 | 0.1 | 0.0 | 0.5 | 0.6 | 0.2 | 0.4 | 0.2 | 0.5 | 0.9 | 0.3 |
| Short access day 10 total locomotion | 0.3 | 0.3 | 1.5 | 0.9 | 0.3 | 1.2 | 0.1 | 0.4 | 0.6 | 0.6 | 0.2 | 0.1 | 0.1 | 0.5 | 0.5 | 0.1 |
| One hour access (0.3 mA shock) | 0.3 | 0.3 | 1.1 | 0.2 | -0.3 | 0.0 | 1.0 | 0.4 | 0.8 | 0.5 | 0.9 | -0.4 | 1.0 | 0.4 | 0.1 | -0.2 |
| Locomotion velocity, session 2 | 0.3 | 0.3 | 0.9 | 0.4 | 0.1 | 1.0 | 0.6 | 0.7 | 0.7 | 0.5 | 0.5 | 0.0 | 0.5 | 0.6 | 0.3 | 0.3 |
| Locomotion velocity, hab. session 1 | 0.3 | 0.4 | 0.9 | 0.2 | 0.7 | -0.7 | 0.9 | 0.6 | 0.4 | 0.4 | 0.9 | 0.6 | 1.0 | 0.4 | 0.5 | 0.5 |
| Delta time to tail flick, test, before/after SA | 0.3 | 0.3 | 0.7 | -0.2 | -0.8 | -0.7 | -0.3 | -0.5 | -0.3 | -0.2 | -0.2 | -0.8 | -0.3 | -0.6 | -0.6 | -0.8 |
| Distance moved, locomotor task time 1 | 0.3 | 0.3 | 0.7 | -0.8 | 0.1 | -0.4 | -0.7 | -0.0 | -0.8 | -0.7 | -0.8 | 0.0 | -0.8 | -0.5 | -0.4 | -0.2 |
| Time >=10cm from walls, locomotor time 2 | 0.3 | 0.3 | 0.6 | 0.2 | 0.4 | 0.5 | 0.6 | 0.5 | 0.4 | 0.6 | 0.5 | 0.2 | 0.5 | 0.5 | 0.8 | 0.8 |
| Latency to leave start box in cocaine runway, M | 0.3 | 0.3 | 0.7 | 0.8 | 0.4 | -0.2 | 0.6 | 0.5 | 0.5 | 0.4 | 0.7 | 0.5 | 0.7 | 0.6 | 0.7 | 0.6 |
| Mn content in liver | 0.3 | 0.4 | 0.8 | 0.9 | 0.5 | 0.8 | 0.5 | 0.5 | 0.6 | 0.7 | 0.5 | 0.5 | 0.5 | 0.6 | 0.7 | 0.5 |
| Parametrial fat weight | 0.2 | 0.3 | 1.1 | -0.7 | 0.8 | 0.2 | 0.4 | 1.0 | -0.0 | -0.2 | 0.0 | 1.1 | 0.2 | 0.3 | 0.3 | 0.8 |
| Tibialis anterior weight | 0.2 | 0.8 | 3.7 | -0.1 | 1.0 | 1.3 | 0.6 | 1.9 | 0.4 | 0.5 | 0.2 | 1.1 | 0.4 | 0.8 | 0.5 | 1.0 |
| Indifference point function ln k | 0.2 | 0.3 | 0.6 | 0.3 | 0.5 | 0.6 | 0.5 | 0.4 | 0.4 | 0.8 | 0.4 | 0.8 | 0.5 | 0.4 | 0.7 | 0.3 |
| Indifference point function log k | 0.2 | 0.3 | 0.6 | 0.3 | 0.5 | 0.6 | 0.5 | 0.4 | 0.4 | 0.8 | 0.4 | 0.8 | 0.5 | 0.4 | 0.7 | 0.3 |
| Locomotor testing distance | 0.2 | 0.3 | 0.6 | -0.5 | -0.4 | 0.0 | -0.7 | -0.3 | -0.6 | -0.3 | -0.8 | -0.6 | -0.7 | -0.6 | -0.4 | -0.4 |
| Reaction time trials AUC | 0.2 | 0.3 | 0.8 | 0.0 | 0.5 | 0.7 | 0.6 | 0.9 | 0.4 | 0.7 | 0.4 | 0.7 | 0.5 | 0.4 | 0.6 | 0.1 |
| Social time | 0.2 | 0.2 | 0.5 | -0.2 | 0.1 | -0.5 | -0.5 | -0.7 | -0.4 | -0.5 | -0.4 | 0.2 | -0.5 | -0.3 | -0.5 | -0.5 |
| Intermittent access day 15 total infusions | 0.2 | 0.2 | 0.7 | -0.8 | -0.4 | -0.8 | 0.6 | 0.8 | -0.1 | -0.1 | 0.3 | -0.4 | 0.5 | -0.2 | -0.0 | -0.1 |
| Baseline Anxiety | 0.2 | 0.2 | 0.5 | -0.4 | -0.4 | -0.7 | -0.2 | -0.7 | -0.3 | -0.5 | -0.2 | -0.1 | -0.2 | -0.4 | -0.5 | -0.4 |
| Stereotopy head waving duration, day 3 | 0.2 | 0.3 | 0.7 | 0.2 | 0.1 | -0.1 | -0.8 | -0.4 | -0.6 | -0.8 | -0.7 | 0.3 | -0.7 | -0.2 | -0.7 | 0.1 |
| Total locomotion distance, hab. session 1 | 0.2 | 0.3 | 1.0 | -0.4 | 0.6 | -1.0 | 0.8 | 0.6 | -0.0 | 0.0 | 0.5 | 0.5 | 0.7 | 0.1 | 0.1 | 0.4 |
| Total zone transitions, hab. session 2 | 0.2 | 0.3 | 0.8 | -0.4 | 0.3 | -0.2 | 0.9 | 0.9 | 0.2 | 0.5 | 0.5 | 0.1 | 0.7 | 0.2 | 0.4 | 0.3 |
| Total locomotion distance, hab. session 2 | 0.2 | 0.3 | 1.2 | -0.9 | -0.4 | -1.1 | 0.2 | 0.2 | -0.5 | -0.2 | -0.0 | -0.6 | 0.1 | -0.5 | -0.3 | -0.4 |
| Locomotion velocity, hab. session 2 | 0.2 | 0.3 | 1.4 | -1.0 | -0.4 | -1.2 | 0.3 | 0.2 | -0.5 | -0.2 | -0.0 | -0.6 | 0.2 | -0.5 | -0.3 | -0.4 |
| Bone: final moment | 0.2 | 0.3 | 0.7 | 0.3 | 0.4 | 0.8 | 0.5 | 0.8 | 0.5 | 0.5 | 0.4 | 0.7 | 0.5 | 0.6 | 0.6 | 0.8 |
| Bone: post-yield work | 0.2 | 0.2 | 0.7 | -0.3 | 0.1 | -0.1 | -0.8 | -0.1 | -0.6 | -0.5 | -0.8 | -0.1 | -0.8 | -0.2 | -0.5 | 0.1 |
| Distance traveled before self-admin | 0.2 | 0.2 | 0.7 | 0.2 | 0.0 | 0.0 | -0.8 | -0.8 | -0.3 | -0.5 | -0.6 | -0.0 | -0.7 | -0.2 | -0.2 | -0.1 |
| Diff in mean of infusions in LGA sessions | 0.2 | 0.2 | 1.0 | 0.6 | 1.0 | -0.2 | -0.2 | 0.2 | -0.1 | 0.1 | 0.0 | 0.7 | -0.1 | 0.4 | 0.3 | 0.7 |
| Delta distance traveled before/after self-admin | 0.2 | 0.2 | 0.4 | 0.5 | 0.4 | 0.1 | 0.5 | 0.3 | 0.4 | 0.6 | 0.6 | 0.6 | 0.6 | 0.4 | 0.5 | 0.3 |
| Time in open arm before self-admin | 0.2 | 0.3 | 1.0 | -0.6 | -0.4 | -0.3 | -0.3 | 0.3 | -0.5 | -0.9 | -0.5 | -0.1 | -0.4 | -0.3 | -1.0 | -0.4 |
| Ambulatory time before self-admin | 0.2 | 0.2 | 0.5 | 0.7 | 0.7 | 0.4 | -0.4 | 0.1 | 0.1 | 0.0 | -0.1 | 0.4 | -0.2 | 0.4 | 0.4 | 0.6 |
| Total heroin consumption | 0.2 | 0.2 | 0.5 | 0.0 | 0.7 | -0.6 | -0.5 | 0.2 | -0.4 | -0.5 | -0.3 | 0.7 | -0.4 | 0.0 | -0.2 | 0.4 |
| Delay disc. indifference point, 8s delay | 0.2 | 0.2 | 0.6 | 0.6 | 0.1 | -0.1 | 0.6 | -0.2 | 0.6 | 0.3 | 0.7 | 0.3 | 0.7 | 0.4 | 0.1 | 0.2 |
| Food seeking constrained by brief footshock | 0.2 | 0.3 | 0.6 | 0.0 | -0.5 | 0.4 | -0.8 | -0.3 | -0.4 | -0.2 | -0.7 | -0.8 | -0.7 | -0.3 | -0.5 | -0.5 |
| Retroperitoneal fat weight | 0.1 | 0.4 | 2.3 | 0.0 | 0.8 | 1.5 | -0.6 | 0.4 | 0.2 | 0.1 | -0.4 | 0.9 | -0.6 | 0.4 | 0.4 | 0.6 |
| Delay discounting water rate 0 sec | 0.1 | 0.1 | 0.4 | -0.0 | -0.4 | 0.6 | 0.2 | 0.4 | 0.1 | 0.1 | -0.1 | -0.7 | 0.1 | -0.1 | 0.3 | -0.2 |
| Delay discounting water rate 6 sec | 0.1 | 0.2 | 0.5 | -0.2 | 0.1 | 0.1 | -0.7 | -0.4 | -0.6 | -0.3 | -0.7 | 0.2 | -0.6 | -0.4 | 0.2 | 0.2 |
| Social response proportion | 0.1 | 0.1 | 0.6 | -0.3 | 0.4 | -0.2 | 0.5 | 0.7 | 0.0 | -0.2 | 0.2 | 0.4 | 0.4 | 0.3 | -0.2 | -0.4 |
| Pavlov. Cond. lever contacts | 0.1 | 0.2 | 0.4 | 0.6 | 0.3 | 0.1 | 0.4 | -0.2 | 0.6 | 0.2 | 0.6 | 0.4 | 0.4 | 0.4 | 0.1 | 0.0 |
| Pavlov. Cond. magazine entry number | 0.1 | 0.1 | 0.2 | 0.4 | -0.3 | 0.5 | 0.1 | -0.4 | 0.3 | 0.4 | 0.1 | -0.1 | 0.1 | 0.0 | 0.5 | 0.1 |
| Pavlov. Cond. response bias | 0.1 | 0.1 | 0.3 | 0.3 | 0.4 | -0.3 | 0.4 | 0.1 | 0.4 | 0.0 | 0.5 | 0.4 | 0.4 | 0.3 | -0.1 | 0.0 |
| Intermittent access terminal intake (last 3 days) | 0.1 | 0.1 | 0.6 | -0.6 | -0.6 | -0.7 | 0.2 | 0.1 | -0.2 | -0.2 | 0.0 | -0.6 | 0.1 | -0.4 | -0.0 | -0.3 |
| Intermittent access standard deviation | 0.1 | 0.1 | 0.5 | -0.1 | -0.7 | 0.2 | -0.1 | -0.2 | -0.0 | 0.1 | -0.1 | -0.7 | -0.1 | -0.2 | 0.0 | -0.5 |
| Cocaine induced anxiety | 0.1 | 0.1 | 0.3 | -0.4 | -0.2 | -0.3 | -0.3 | -0.1 | -0.3 | -0.2 | -0.3 | -0.5 | -0.3 | -0.3 | 0.2 | -0.1 |
| Short access day 1 total infusions | 0.1 | 0.1 | 0.3 | -0.3 | -0.4 | 0.3 | -0.4 | 0.4 | -0.3 | -0.2 | -0.5 | -0.5 | -0.4 | -0.2 | 0.2 | -0.0 |
| Stereotopy head waving bouts, day 3 | 0.1 | 0.1 | 0.5 | -0.0 | 0.2 | 0.3 | -0.1 | 0.7 | -0.2 | -0.4 | -0.3 | 0.5 | -0.1 | 0.1 | -0.4 | 0.2 |
| Locomotion distance, session 7 | 0.1 | 0.1 | 0.6 | 0.3 | 0.3 | -0.8 | 0.3 | 0.1 | 0.1 | -0.4 | 0.4 | 0.0 | 0.4 | 0.3 | -0.4 | 0.4 |
| Condit. Reinf. active responses | 0.1 | 0.2 | 0.3 | -0.3 | -0.4 | 0.1 | -0.6 | -0.4 | -0.4 | -0.4 | -0.6 | -0.3 | -0.6 | -0.4 | -0.3 | -0.4 |
| Incentive salience index mean | 0.1 | 0.2 | 0.4 | 0.4 | 0.5 | 0.6 | 0.1 | 0.4 | 0.3 | 0.3 | 0.1 | 0.6 | 0.1 | 0.4 | 0.4 | 0.5 |
| Novel to familiar place preference ratio | 0.1 | 0.1 | 0.4 | -0.2 | -0.4 | -0.1 | 0.1 | 0.1 | 0.0 | -0.0 | 0.0 | -0.6 | 0.0 | -0.2 | -0.2 | -0.5 |
| Novelty place preference | 0.1 | 0.1 | 0.4 | -0.2 | -0.5 | -0.1 | 0.0 | 0.1 | -0.0 | -0.1 | -0.0 | -0.7 | -0.0 | -0.2 | -0.3 | -0.6 |
| Time in novel zone, NPP test | 0.1 | 0.1 | 0.3 | -0.1 | -0.4 | 0.1 | 0.1 | 0.1 | 0.1 | 0.0 | 0.1 | -0.6 | 0.1 | -0.1 | -0.2 | -0.5 |
| Bone: elastic work | 0.1 | 0.2 | 0.4 | -0.5 | -0.6 | 0.1 | 0.6 | 0.6 | 0.2 | 0.1 | 0.2 | -0.4 | 0.4 | -0.0 | 0.1 | -0.3 |
| Bone: trabecular spacing | 0.1 | 0.1 | 0.4 | 0.5 | 0.3 | -0.0 | 0.2 | -0.3 | 0.3 | 0.4 | 0.4 | 0.4 | 0.3 | 0.3 | 0.6 | 0.2 |
| Extinction: sum of active levers before priming | 0.1 | 0.1 | 0.2 | -0.2 | -0.1 | 0.3 | -0.2 | 0.4 | 0.1 | -0.4 | -0.2 | -0.5 | -0.3 | 0.0 | -0.4 | -0.1 |
| Delta ambulatory time before/after self-admin | 0.1 | 0.1 | 0.6 | 0.4 | 0.5 | 0.0 | -0.0 | -0.2 | 0.0 | 0.3 | 0.1 | 0.8 | 0.1 | 0.2 | 0.4 | 0.4 |
| Time in closed arm before self-admin | 0.1 | 0.2 | 0.7 | -0.8 | 0.3 | -0.3 | -0.2 | 0.1 | -0.6 | -0.3 | -0.5 | 0.2 | -0.3 | -0.4 | 0.2 | 0.2 |
| Sum of active levers in priming session hrs 5-6 | 0.1 | 0.1 | 0.5 | -0.5 | 0.1 | -0.1 | 0.3 | 0.7 | 0.1 | -0.2 | 0.1 | 0.0 | 0.2 | 0.1 | -0.4 | -0.1 |
| Time to tail flick, vehicle, before self-admin | 0.1 | 0.1 | 0.4 | 0.1 | -0.2 | -0.2 | -0.3 | -0.6 | -0.1 | -0.3 | -0.1 | 0.1 | -0.2 | -0.1 | 0.2 | 0.3 |
| Delta time to tail flick, vehicle, before/after SA | 0.1 | 0.1 | 0.2 | 0.2 | 0.4 | 0.3 | 0.3 | 0.1 | 0.4 | 0.5 | 0.3 | 0.1 | 0.3 | 0.3 | 0.5 | -0.0 |
| Run reversals in cocaine runway, males | 0.1 | 0.1 | 0.4 | -0.0 | -0.0 | 0.7 | -0.6 | 0.1 | -0.3 | -0.2 | -0.6 | 0.1 | -0.6 | -0.3 | 0.0 | -0.0 |
| Latency to leave start box in cocaine runway | 0.1 | 0.1 | 0.3 | 0.4 | 0.4 | 0.0 | -0.2 | 0.0 | 0.0 | -0.2 | -0.0 | 0.6 | -0.1 | 0.3 | 0.2 | 0.5 |
| Latency to leave start box in cocaine runway, F | 0.1 | 0.1 | 0.4 | 0.0 | 0.1 | 0.2 | -0.6 | -0.2 | -0.2 | -0.5 | -0.5 | 0.2 | -0.6 | -0.1 | -0.3 | 0.1 |
| Locomotion distance, session 1 | 0.0 | 0.1 | 0.1 | 0.1 | -0.3 | 0.1 | 0.3 | -0.2 | 0.3 | 0.2 | 0.3 | -0.2 | 0.3 | 0.0 | 0.2 | -0.2 |
| Time in novel zone, hab. session 1 | 0.0 | 0.0 | 0.1 | -0.1 | 0.1 | 0.0 | 0.0 | 0.3 | -0.1 | -0.0 | -0.1 | -0.4 | -0.0 | 0.0 | -0.0 | 0.2 |
| Time to tail flick, test, after self-admin | 0.0 | 0.0 | 0.2 | 0.1 | -0.2 | 0.0 | -0.0 | -0.5 | 0.1 | 0.3 | 0.1 | 0.1 | -0.0 | -0.1 | 0.2 | -0.4 |
| Delay disc. indifference point, 0s delay | 0.0 | 0.0 | 0.1 | 0.1 | 0.1 | 0.1 | 0.1 | -0.1 | 0.1 | -0.0 | 0.1 | 0.2 | 0.1 | 0.2 | 0.0 | 0.2 |
| Delay disc. indifference point, 4s delay | 0.0 | 0.0 | 0.1 | 0.2 | -0.2 | -0.2 | -0.1 | -0.4 | 0.1 | -0.4 | 0.1 | -0.0 | -0.1 | 0.1 | -0.4 | -0.2 |
| Co content in liver | 0.0 | 0.0 | 0.3 | 0.1 | 0.2 | -0.6 | 0.1 | 0.1 | -0.1 | -0.1 | 0.2 | -0.1 | 0.2 | 0.1 | -0.1 | 0.0 |
For each tested trait, stats based on TWAS chi2 (squared Z-score) for the above models are shown. Avg chi2 ratio is the mean chi2 across all models for this gene, divided by the mean chi2 across all models for all genes. Avg chi2 is the mean chi2 across all models for this gene. Max chi2 is the highest chi2 across all models for this gene.
The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.