Hub : Genes

Cbx1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative polyA ENSRNOT00000011665 0.02 0.02 2.8e-03 0 0.01 0 0 2.1e-01 9.3e-03 1.4e-01 1.1e-01
2 Adipose alternative polyA ENSRNOT00000094691 0.02 0.01 3.5e-03 0.01 0.01 0 0 5.8e-02 1.1e-02 1.3e-01 1.1e-01
3 BLA gene expression ENSRNOG00000008689 0.09 0.06 7.1e-06 0.07 0.1 0.07 0.07 1.5e-04 8.0e-06 7.5e-05 1.0e-04
4 Brain gene expression ENSRNOG00000008689 0.17 0.1 0.0e+00 0.2 0.21 0.21 0.21 1.0e-18 2.6e-19 4.5e-19 3.7e-19
5 Brain mRNA stability ENSRNOG00000008689 0.03 0.03 7.8e-04 0.04 0.03 0.03 0.03 3.0e-04 5.9e-04 6.5e-04 5.7e-04
6 LHb gene expression ENSRNOG00000008689 0.25 0.18 8.6e-03 0.06 0.06 0.05 0.04 1.7e-02 1.8e-02 2.4e-02 4.2e-02
7 Liver gene expression ENSRNOG00000008689 0.08 0.05 5.0e-13 0.12 0.08 0.1 0.11 8.9e-13 1.9e-09 9.7e-12 4.8e-12
8 Liver mRNA stability ENSRNOG00000008689 0.02 0.02 3.5e-03 0.02 0.01 0.02 0.02 2.1e-03 3.5e-02 3.8e-03 5.6e-03
9 NAcc gene expression ENSRNOG00000008689 0.13 0.09 4.6e-08 0.09 0.1 0.1 0.11 3.0e-07 5.9e-08 5.1e-08 2.9e-08
10 OFC gene expression ENSRNOG00000008689 0.21 0.14 6.3e-04 0.09 0.11 0.09 0.08 4.6e-03 1.7e-03 3.9e-03 7.4e-03
11 OFC intron excision ratio chr10:81785362:81789208 0.15 0.12 8.3e-03 0 0.04 0.01 0.02 2.5e-01 3.6e-02 1.5e-01 1.0e-01
12 OFC intron excision ratio chr10:81785540:81789208 0.16 0.13 8.0e-03 0.08 0.05 0.01 0.02 6.3e-03 3.1e-02 1.8e-01 9.7e-02
13 PL gene expression ENSRNOG00000008689 0.13 0.07 1.8e-12 0.18 0.16 0.17 0.17 2.1e-13 6.6e-12 6.4e-13 4.1e-13
14 PL mRNA stability ENSRNOG00000008689 0.04 0.04 4.3e-03 0.03 0.02 0.02 0.02 4.3e-03 5.7e-03 6.2e-03 9.2e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail13.443.454.56.6-6.7-6.7-6.8-6.4-6.4-6.2-6.1-7.4-6.4-6.56.3-7.1-6.5
BMI without tail1.32.83.41.6-1.7-1.6-1.7-1.7-1.7-1.8-1.8-1.6-1.6-1.81.6-1.6-1.5
Body weight0.41.92.91.2-1.2-1.2-1.7-1.4-1.5-0.9-0.9-1.7-1.1-1.71.3-1.6-1.4
Epididymis fat weight0.00.00.10.1-0.1-0.1-0.20.10.10.40.3-0.4-0.0-0.20.20.10.0
Glucose0.60.92.00.9-0.9-0.9-1.1-0.7-0.8-0.6-0.5-1.1-0.8-1.00.9-1.4-1.2
Heart weight1.42.03.11.3-1.3-1.4-1.5-1.6-1.6-0.7-1.2-1.7-1.3-1.41.3-1.3-1.8
Left kidney weight0.00.10.7-0.40.40.40.00.10.10.80.40.10.5-0.1-0.30.30.1
Right kidney weight0.20.71.20.7-0.8-0.7-1.0-0.8-0.9-0.4-0.6-1.0-0.7-1.10.9-0.6-0.9
Tail length11.936.145.0-6.36.26.36.15.75.65.25.66.76.15.5-5.66.76.2
Length with tail7.627.731.2-5.55.45.65.15.14.95.35.35.55.44.7-4.95.55.2
Length without tail0.30.61.9-0.70.70.70.50.90.81.41.30.30.80.5-0.60.50.7
Liver weight, left0.91.53.3-1.21.21.21.21.11.11.81.21.21.21.2-1.21.10.9
Liver weight, right1.21.93.6-1.51.51.51.31.31.31.91.51.31.51.3-1.51.00.8
Parametrial fat weight0.10.10.60.2-0.1-0.1-0.0-0.2-0.1-0.8-0.60.2-0.2-0.20.10.40.5
Retroperitoneal fat weight0.31.01.70.9-0.9-0.9-1.1-1.0-0.9-0.3-0.6-0.9-1.0-1.21.2-1.3-1.3
Intraocular pressure1.42.03.2-1.41.41.51.51.61.50.61.11.71.41.3-1.41.81.3
Extensor digitorum longus weight0.10.41.40.6-0.6-0.6-0.9-0.4-0.30.00.1-1.2-0.5-0.80.7-0.4-0.4
Soleus weight1.13.34.61.8-1.8-1.8-1.9-1.8-1.8-1.1-1.4-2.0-1.8-1.81.7-2.1-2.1
Tibialis anterior weight0.31.12.2-0.90.91.00.91.11.11.51.40.81.00.9-0.81.41.0
Tibia length0.31.01.61.0-1.0-1.0-1.2-0.8-0.8-0.6-0.6-1.3-0.9-1.20.8-1.2-1.1
Number of licking bursts0.10.10.1-0.20.30.30.40.40.40.20.20.30.20.3-0.30.40.4
Food consumed during 24 hour testing period1.51.92.8-1.31.31.31.41.31.31.21.21.41.31.3-1.31.71.6
Times rat made contact with spout0.10.10.2-0.20.20.20.30.20.20.1-0.00.40.20.3-0.20.40.4
Mean time between licks in bursts0.10.20.60.4-0.4-0.4-0.5-0.3-0.3-0.2-0.2-0.8-0.4-0.40.4-0.5-0.0
Mean num. licks in bursts0.00.00.1-0.20.20.20.20.10.10.20.20.20.20.2-0.20.20.2
Std. dev. time between licks in bursts1.11.31.61.2-1.2-1.1-1.1-1.3-1.3-1.1-1.2-1.0-1.2-1.21.3-1.1-1.0
Water consumed over 24 hours0.20.20.4-0.40.40.40.50.50.50.50.40.40.40.5-0.60.50.6
Indifference point 0 sec0.91.42.11.2-1.2-1.2-1.2-1.3-1.4-1.4-1.3-1.0-1.2-1.31.3-0.5-0.8
Indifference point AUC0.10.20.3-0.40.40.40.50.50.50.30.40.60.40.5-0.30.40.2
Indifference point function ln k0.00.00.30.0-0.00.0-0.00.10.1-0.20.00.0-0.0-0.10.20.50.3
Indifference point function log k0.00.00.30.0-0.00.0-0.00.10.1-0.20.00.0-0.0-0.10.20.50.3
Delay discounting total patch changes 0 sec0.91.42.21.2-1.2-1.1-1.2-1.3-1.4-1.5-1.3-1.1-1.2-1.31.3-0.6-0.9
Delay discounting total patch changes 12 sec0.20.20.80.5-0.5-0.5-0.3-0.3-0.4-0.9-0.7-0.1-0.5-0.40.50.1-0.3
Delay discounting total patch changes 18 sec1.41.82.11.4-1.4-1.4-1.4-1.3-1.4-1.5-1.2-1.2-1.5-1.31.4-1.2-1.4
Delay discounting total patch changes 24 sec1.51.93.51.3-1.3-1.3-1.3-1.6-1.7-1.9-1.7-1.0-1.3-1.31.3-0.9-1.3
Delay discounting total patch changes 6 sec0.71.11.61.2-1.2-1.1-1.1-0.9-1.0-1.3-1.0-0.9-1.2-1.11.2-0.6-0.9
Delay discounting time to switch 0 sec0.10.10.20.3-0.3-0.3-0.2-0.4-0.3-0.3-0.5-0.1-0.4-0.30.2-0.3-0.3
Delay discounting water rate 0 sec0.71.11.50.9-1.0-1.0-1.2-1.1-1.1-0.9-0.9-1.2-0.9-1.11.0-1.0-1.1
Delay discounting water rate 12 sec0.10.10.3-0.30.30.30.10.40.40.30.6-0.10.40.2-0.30.30.4
Delay discounting water rate 18 sec0.40.50.8-0.80.80.80.60.60.60.60.80.50.90.7-0.80.80.8
Delay discounting water rate 24 sec0.60.91.20.9-0.9-0.9-1.0-1.0-0.9-0.9-0.8-1.1-0.9-1.00.9-1.0-1.0
Delay discounting water rate 6 sec0.00.00.1-0.20.20.20.10.00.10.20.20.10.20.3-0.3-0.00.0
Locomotor activity0.61.01.91.0-1.0-1.0-0.8-1.1-1.1-1.4-1.4-0.6-1.0-0.90.8-0.7-0.8
Locomotor testing distance1.11.93.71.4-1.4-1.4-1.2-1.4-1.5-1.9-1.7-0.9-1.5-1.21.2-0.9-1.1
Locomotor testing rearing0.10.10.40.3-0.3-0.3-0.1-0.4-0.4-0.6-0.5-0.0-0.3-0.00.0-0.2-0.5
Light reinforcement 10.40.71.00.9-0.8-0.9-0.7-0.7-0.8-1.0-1.0-0.5-0.9-0.70.7-0.8-1.0
Light reinforcement 20.10.10.50.2-0.2-0.1-0.1-0.1-0.2-0.7-0.40.1-0.2-0.10.20.1-0.0
Reaction time number correct0.10.10.5-0.30.30.20.10.20.20.70.7-0.10.40.3-0.50.1-0.0
Reaction time mean minus median0.60.81.6-0.70.70.81.01.11.10.30.61.20.60.8-0.61.21.2
Reaction time mean minus median AUC0.81.02.1-0.80.80.91.21.31.20.40.71.40.71.0-0.71.31.3
Reaction time num false alarms0.30.41.3-0.60.60.60.60.40.40.30.60.70.50.6-0.31.20.9
Reaction time num false alarms AUC0.40.51.5-0.70.70.70.70.50.50.30.70.80.60.7-0.31.20.9
Reaction time trials correct on left0.10.10.5-0.30.30.20.10.20.20.70.7-0.10.40.3-0.50.1-0.0
Reaction time trials on left0.10.10.5-0.30.30.30.10.20.20.70.7-0.10.40.4-0.50.20.0
Reaction time mean0.10.10.30.2-0.1-0.10.30.40.3-0.6-0.30.5-0.20.00.20.60.5
Reaction time mean AUC0.10.20.60.1-0.10.00.30.40.4-0.5-0.30.5-0.20.10.10.70.7
Median of all reaction times0.20.20.70.5-0.5-0.5-0.2-0.2-0.2-0.8-0.70.0-0.6-0.40.6-0.0-0.0
Reaction time omissions0.10.10.5-0.10.10.20.40.50.5-0.1-0.10.70.00.1-0.00.60.6
Reaction time false alarm rate0.10.20.7-0.30.30.40.40.20.2-0.20.10.70.20.30.10.80.7
Reaction time premature initiation rate0.40.51.0-0.70.70.70.70.70.70.30.70.70.70.6-0.50.81.0
Reaction time premature initiations0.60.91.3-0.90.90.90.90.90.90.81.10.80.90.9-0.81.11.1
Std. dev. reaction times0.40.51.2-0.50.50.60.80.90.80.20.41.10.40.6-0.31.11.1
Reaction time trials completed0.10.10.5-0.30.30.30.10.20.20.70.7-0.10.40.4-0.50.20.0
Reaction time trials AUC0.10.10.5-0.30.30.30.20.20.20.70.7-0.10.40.4-0.50.20.0
Social response proportion0.91.01.7-1.11.11.11.00.90.71.10.81.31.00.8-0.80.91.0
Social responses0.10.10.3-0.20.20.20.30.1-0.00.5-0.20.40.20.1-0.20.20.3
Social time0.00.00.20.1-0.1-0.10.10.1-0.1-0.3-0.50.0-0.10.1-0.1-0.10.1
Conditioned locomotion1.11.41.91.1-1.1-1.1-1.2-1.0-1.1-1.2-1.1-1.2-1.1-1.20.9-1.4-1.3
Cocaine response after cond. corrected6.06.88.02.6-2.6-2.6-2.6-2.5-2.5-2.8-2.8-2.6-2.5-2.72.5-2.6-2.5
Cocaine response after cond. not corrected3.33.74.71.9-1.9-1.8-1.9-1.9-1.8-2.2-2.1-1.9-1.9-2.01.8-2.0-1.9
Cocaine response before conditioning2.53.03.8-1.81.81.81.81.61.71.71.71.91.71.8-1.61.71.7
Saline control response0.10.20.5-0.40.40.40.40.30.30.70.50.20.40.5-0.70.10.1
Condit. Reinf. active minus inactive responses0.10.10.20.4-0.3-0.3-0.3-0.4-0.4-0.2-0.2-0.2-0.4-0.30.5-0.2-0.3
Condit. Reinf. active-inactive response ratio0.40.40.60.7-0.7-0.7-0.6-0.7-0.7-0.6-0.6-0.4-0.8-0.60.8-0.6-0.7
Condit. Reinf. active responses0.00.00.10.0-0.0-0.00.00.00.00.10.10.2-0.10.00.10.20.2
Condit. Reinf. inactive responses0.30.30.6-0.50.50.50.50.70.60.60.60.50.50.6-0.60.60.8
Condit. Reinf. lever presses0.81.11.4-1.01.01.01.01.11.11.01.11.20.91.0-0.91.11.1
Condit. Reinf. lever reinforcers received0.10.10.2-0.20.20.20.20.30.30.30.30.30.10.2-0.20.40.5
Pavlov. Cond. lever latency0.60.91.7-0.90.90.90.90.80.90.80.80.90.90.9-0.91.31.1
Pavlov. Cond. magazine entry latency0.50.50.6-0.80.80.80.70.70.70.80.80.70.80.7-0.70.50.6
Pavlov. Cond. change in total contacts0.10.20.30.5-0.5-0.5-0.4-0.4-0.5-0.4-0.4-0.2-0.5-0.50.5-0.5-0.3
Pavlov. Cond. index score0.20.30.60.5-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.4-0.5-0.60.6-0.8-0.6
Pavlov. Cond. latency score0.10.10.30.3-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.2-0.3-0.40.4-0.5-0.4
Pavlov. Cond. lever contacts0.50.71.40.8-0.8-0.8-0.8-0.8-0.8-0.7-0.8-0.8-0.8-0.80.8-1.2-1.0
Pavlov. Cond. magazine entry number0.00.00.10.0-0.0-0.00.0-0.1-0.10.0-0.0-0.1-0.00.1-0.10.30.0
Pavlov. Cond. intertrial magazine entries1.92.43.1-1.51.51.51.51.61.61.71.81.41.51.6-1.51.51.4
Pavlov. Cond. lever-magazine prob. diff.0.30.40.70.6-0.6-0.6-0.6-0.6-0.6-0.5-0.5-0.5-0.6-0.70.6-0.8-0.7
Pavlov. Cond. response bias0.50.71.20.8-0.8-0.8-0.8-0.7-0.8-0.7-0.7-0.7-0.8-0.80.8-1.1-0.9
Conditioned reinforcement - actives1.21.22.01.1-1.1-1.0-0.9-1.0-1.0-1.4-1.2-0.7-1.2-1.01.4-0.7-0.9
Conditioned reinforcement - inactives0.50.51.2-0.60.60.60.60.50.50.81.10.50.70.8-0.90.90.7
Conditioned locomotion3.84.67.52.1-2.1-2.1-2.0-2.3-2.5-2.2-2.2-1.6-2.3-2.22.7-1.5-1.8
Intermittent access intake day 1-15 change2.42.43.21.4-1.5-1.4-1.6-1.8-1.7-1.3-1.1-1.4-1.5-1.51.8-1.7-1.7
Intermittent access intake escalation2.42.43.31.4-1.4-1.4-1.5-1.8-1.6-1.4-1.3-1.2-1.5-1.51.8-1.7-1.7
Intermittent access intake escalation 21.91.94.11.3-1.3-1.3-1.4-1.4-1.3-1.2-0.9-1.1-1.3-1.31.4-2.0-1.7
Intermitt. access day 1 inactive lever presses0.20.20.8-0.40.40.30.40.50.50.70.90.10.40.6-0.70.10.0
Intermitt. access day 15 inactive lever presses0.40.41.20.7-0.7-0.7-0.5-0.6-0.6-0.5-0.5-0.6-0.7-0.40.4-0.9-1.1
Intermitt. access escalation Index2.01.84.71.2-1.2-1.2-1.1-1.4-1.4-2.0-2.2-0.6-1.3-1.41.4-0.9-0.7
Intermittent access day 1 total infusions0.30.41.1-0.50.50.50.60.80.80.20.10.50.50.5-0.51.10.8
Intermittent access day 15 total infusions0.20.20.60.4-0.4-0.4-0.3-0.4-0.4-0.8-0.7-0.1-0.5-0.40.6-0.1-0.3
Intermittent access terminal intake (last 3 days)0.20.20.50.4-0.4-0.4-0.3-0.4-0.4-0.7-0.6-0.2-0.5-0.40.4-0.4-0.5
Intermittent access total infusions0.00.00.20.1-0.1-0.00.00.0-0.0-0.4-0.40.1-0.1-0.10.10.40.1
Intermittent access day 1 locomotion0.20.20.5-0.50.50.50.60.40.30.20.20.70.40.5-0.40.70.6
Intermittent access day 15 total locomotion0.30.30.60.5-0.5-0.5-0.4-0.8-0.7-0.5-0.6-0.2-0.6-0.50.6-0.4-0.5
Intermittent access total locomotion0.50.61.00.7-0.7-0.7-0.6-1.0-1.0-0.8-0.9-0.2-0.8-0.81.0-0.4-0.6
Intermittent access standard deviation2.02.23.91.3-1.3-1.3-1.4-1.7-1.6-1.2-1.4-1.1-1.4-1.31.5-1.8-2.0
Cocaine induced anxiety0.10.10.10.2-0.2-0.2-0.3-0.3-0.4-0.1-0.3-0.2-0.2-0.20.3-0.3-0.3
Post-drug Anxiety0.40.50.7-0.60.70.60.70.80.70.90.60.70.60.8-0.80.50.5
Baseline Anxiety0.00.00.10.0-0.0-0.10.10.20.30.10.30.0-0.00.3-0.3-0.2-0.1
Lifetime Intake0.10.10.5-0.10.10.10.20.20.1-0.3-0.30.30.10.1-0.10.70.3
Incentive Sensitization - Responses0.00.00.10.2-0.2-0.2-0.2-0.3-0.2-0.1-0.0-0.2-0.2-0.10.20.2-0.3
Incentive Sensitization - Breakpoint0.10.10.30.4-0.4-0.4-0.4-0.5-0.4-0.3-0.2-0.4-0.4-0.40.4-0.0-0.5
Progressive ratio test 1 active lever presses0.30.31.5-0.30.30.40.50.50.4-0.0-0.10.50.30.3-0.21.21.0
Progressive ratio test 1 breakpoint0.40.51.8-0.50.50.60.70.70.70.30.20.60.50.5-0.51.31.1
Progressive ratio test 1 inactive lever presses0.00.00.10.3-0.3-0.3-0.2-0.0-0.1-0.2-0.3-0.3-0.2-0.20.10.30.0
Progressive ratio test 2 active lever presses0.10.21.0-0.20.20.30.40.30.40.0-0.00.40.20.3-0.11.00.5
Progressive ratio test 2 breakpoint0.10.10.8-0.10.10.10.20.10.2-0.1-0.10.20.10.2-0.00.90.5
Progressive ratio test 2 inactive lever presses0.10.10.2-0.20.20.20.20.30.20.20.10.10.20.4-0.40.30.0
Total sessions with >9 infusions0.20.30.60.5-0.5-0.4-0.3-0.4-0.5-0.8-0.80.0-0.6-0.60.8-0.0-0.1
Short access day 1 total inactive lever presses3.33.65.6-1.81.91.81.91.91.81.91.71.81.92.1-2.42.01.6
Short access day 10 total inactive lever presses0.60.71.8-0.70.70.70.70.90.91.31.20.30.81.0-1.00.10.3
Short access day 1 total infusions0.10.10.3-0.20.20.20.30.30.2-0.1-0.20.50.10.2-0.20.30.0
Short access day 10 total infusions0.30.30.90.5-0.5-0.5-0.5-0.5-0.6-0.9-0.9-0.4-0.5-0.60.6-0.2-0.5
Short access total infusions0.00.00.10.1-0.1-0.1-0.1-0.0-0.1-0.4-0.3-0.1-0.1-0.10.10.3-0.1
Short access day 1 locomotion0.80.91.60.8-0.8-0.8-0.8-1.1-1.1-0.8-0.9-0.5-0.9-0.81.0-1.2-1.3
Short access day 10 total locomotion0.40.51.60.5-0.5-0.5-0.5-1.1-1.3-0.3-0.4-0.1-0.6-0.60.9-0.7-0.7
Short access total locomotion0.90.91.70.8-0.8-0.8-0.9-1.3-1.3-0.6-0.6-0.6-0.9-0.91.0-1.1-1.2
Compulsive drug intake8.07.910.0-2.82.82.82.93.23.12.32.32.82.82.8-2.73.03.1
One hour access (0.3 mA shock)0.60.71.3-0.80.80.80.90.90.90.50.50.70.80.9-0.71.11.0
One hour access (shock baseline)2.73.13.71.7-1.7-1.7-1.7-1.9-1.9-1.8-1.6-1.6-1.7-1.71.8-1.7-1.9
Number of responses in last shaping day0.10.10.60.4-0.4-0.4-0.3-0.1-0.0-0.1-0.1-0.8-0.2-0.20.0-0.10.1
Context. condit. distance diff. score0.20.30.60.6-0.6-0.6-0.6-0.4-0.4-0.4-0.7-0.8-0.5-0.60.5-0.6-0.4
Locomotion velocity, session 10.40.50.80.7-0.7-0.7-0.6-0.7-0.8-0.3-0.7-0.5-0.7-0.70.8-0.6-0.9
Locomotion distance, session 12.63.44.9-1.91.91.91.71.61.62.22.11.91.81.7-1.71.91.7
Locomotion velocity, session 21.01.11.7-1.11.11.11.00.90.81.31.01.21.10.9-0.91.31.0
Locomotion distance, session 23.24.55.9-2.22.22.22.11.91.92.42.32.32.12.0-2.02.11.9
Locomotion velocity, session 30.00.00.1-0.20.10.1-0.00.10.10.10.4-0.10.20.1-0.10.20.1
Locomotion distance, session 33.23.54.2-1.91.91.91.82.01.91.72.11.71.91.8-1.81.91.8
Stereotopy head waving bouts, day 34.65.56.42.4-2.3-2.4-2.3-2.4-2.3-2.2-2.5-2.2-2.3-2.32.2-2.5-2.5
Stereotopy head waving duration, day 33.44.14.72.0-2.0-2.0-2.0-2.1-2.1-1.7-2.1-2.0-2.0-2.02.0-2.1-2.2
Locomotion velocity, session 71.41.52.3-1.31.31.31.11.21.21.41.51.01.31.2-1.21.11.3
Locomotion distance, session 75.26.67.1-2.72.62.72.62.62.62.42.62.62.62.5-2.52.42.5
Stereotopy head waving bouts, day 70.60.71.20.8-0.8-0.9-0.8-0.9-0.8-1.1-1.0-0.8-0.9-0.80.8-0.6-0.7
Stereotopy head waving duration, day 70.30.30.60.6-0.6-0.6-0.5-0.6-0.6-0.8-0.7-0.5-0.6-0.50.5-0.4-0.5
Locomotion velocity, session 80.10.20.50.3-0.4-0.4-0.5-0.3-0.30.1-0.2-0.7-0.3-0.40.3-0.7-0.4
Locomotion distance, session 80.61.01.8-1.01.01.00.91.00.91.41.00.91.00.8-0.90.90.9
Degree of sensitization distance0.00.00.0-0.10.10.10.0-0.1-0.00.20.10.10.10.1-0.1-0.1-0.0
Degree of sensitization stereotypy0.10.10.2-0.10.20.10.30.20.2-0.4-0.00.20.10.3-0.20.40.4
Condit. Reinf. active minus inactive responses0.20.20.5-0.40.40.40.50.30.3-0.00.10.60.30.4-0.30.50.7
Condit. Reinf. active-inactive response ratio0.20.20.80.4-0.4-0.4-0.3-0.6-0.6-0.9-0.7-0.2-0.5-0.40.5-0.3-0.1
Condit. Reinf. active responses0.10.10.4-0.30.30.30.40.30.4-0.10.10.60.20.4-0.40.40.4
Condit. Reinf. inactive responses0.30.40.7-0.60.60.60.70.80.90.40.50.80.50.7-0.80.50.4
Incentive salience index mean0.40.51.0-0.60.60.70.80.50.50.30.41.00.60.7-0.50.91.0
Condit. Reinf. lever presses0.91.21.9-1.11.11.11.21.01.00.91.11.31.01.2-1.01.41.2
Time in familiar zone, hab. session 10.40.40.8-0.50.60.50.70.90.90.50.50.50.60.8-0.80.50.5
Time in novel zone, hab. session 13.13.13.51.7-1.7-1.7-1.8-1.9-1.9-1.6-1.7-1.7-1.7-1.81.8-1.8-1.6
Total zone transitions, hab. session 16.49.110.2-3.03.03.03.03.03.03.13.22.93.03.0-3.02.82.9
Total locomotion distance, hab. session 12.84.05.4-2.02.02.02.02.02.02.32.12.01.92.0-2.01.92.0
Locomotion velocity, hab. session 13.75.37.0-2.32.32.32.32.22.22.72.42.32.32.3-2.32.22.3
Time in familiar zone, hab. session 20.50.51.20.7-0.7-0.8-0.7-0.5-0.5-0.6-0.6-0.9-0.7-0.50.6-1.0-1.1
Time in novel zone, hab. session 20.10.10.4-0.30.30.30.20.20.20.30.20.30.30.2-0.20.40.6
Total zone transitions, hab. session 22.02.63.4-1.61.61.61.61.51.51.61.51.81.51.6-1.51.81.7
Total locomotion distance, hab. session 20.10.10.5-0.20.20.20.20.10.10.70.30.40.10.2-0.10.20.2
Locomotion velocity, hab. session 20.10.10.6-0.30.30.30.30.20.20.80.30.60.30.2-0.20.30.3
Novel to familiar place preference ratio0.80.91.2-1.01.01.00.91.01.00.70.80.81.00.8-1.00.91.1
Novelty place preference1.01.01.4-1.11.01.11.01.11.10.80.90.91.10.9-1.10.91.2
Time in novel zone, NPP test0.70.81.1-0.90.90.90.81.01.00.60.80.71.00.8-1.00.81.1
Total zone transitions, NPP test3.75.36.9-2.32.32.32.32.12.02.62.52.42.22.3-2.12.42.2
Total locomotion distance, NPP test0.91.32.7-1.11.11.11.01.00.91.71.51.11.01.1-0.91.21.0
Locomotion velocity, NPP test1.52.14.1-1.51.51.51.31.31.22.01.81.51.41.4-1.31.51.3
Pavlov. Cond. lever latency1.31.72.61.3-1.3-1.2-1.3-1.1-1.2-1.2-1.4-1.2-1.2-1.41.2-1.6-1.4
Pavlov. Cond. magazine entry latency0.00.00.2-0.00.00.00.20.00.1-0.3-0.20.4-0.00.2-0.00.50.3
Pavlov. Cond. change in total contacts2.22.33.3-1.41.51.51.71.51.61.01.21.71.41.6-1.61.81.7
Pavlov. Cond. index score0.50.61.4-0.70.70.70.90.60.70.40.60.90.60.9-0.71.21.0
Pavlov. Cond. latency score0.60.71.5-0.80.80.80.90.70.80.60.70.90.70.9-0.81.21.0
Pavlov. Cond. lever contacts1.92.23.9-1.41.41.41.51.31.41.21.41.51.41.6-1.42.01.7
Pavlov. Cond. magazine entry number0.20.20.80.3-0.4-0.3-0.6-0.3-0.4-0.1-0.2-0.7-0.3-0.60.4-0.9-0.8
Pavlov. Cond. intertrial magazine entries0.50.61.0-0.80.80.80.71.01.00.70.90.70.80.7-0.90.40.5
Pavlov. Cond. lever-magazine prob. diff.0.40.51.4-0.60.70.60.80.60.60.30.50.90.60.8-0.61.20.9
Pavlov. Cond. response bias0.50.61.5-0.70.70.70.90.70.80.30.60.90.60.9-0.71.21.0
Bone: apparent density1.52.53.11.6-1.6-1.6-1.5-1.7-1.7-1.6-1.8-1.5-1.6-1.61.4-1.6-1.7
Bone surface0.40.61.00.7-0.8-0.8-0.8-0.8-0.8-1.0-1.0-0.8-0.7-0.80.5-0.7-1.0
Bone volume1.22.12.51.4-1.4-1.4-1.4-1.5-1.5-1.5-1.6-1.5-1.4-1.51.2-1.3-1.5
Bone: connectivity density0.10.20.70.4-0.4-0.4-0.3-0.4-0.4-0.9-0.7-0.4-0.4-0.30.2-0.4-0.6
Bone: cortical apparent density6.28.110.1-2.72.82.73.03.23.12.52.52.72.83.1-3.02.63.2
Bone: cortical area0.00.10.10.2-0.2-0.2-0.3-0.4-0.40.1-0.2-0.3-0.2-0.30.00.1-0.0
Bone: cortical porosity0.50.51.00.7-0.7-0.7-0.7-0.7-0.7-1.0-0.6-0.6-0.7-0.70.7-0.5-0.7
Bone: cortical porosity0.30.40.60.6-0.6-0.6-0.6-0.6-0.6-0.8-0.5-0.5-0.6-0.60.7-0.4-0.6
Bone: cortical thickness0.20.30.6-0.50.50.50.50.50.50.80.60.20.60.5-0.80.50.7
Bone: cortical thickness1.21.42.4-1.31.21.31.31.11.11.00.91.61.21.1-1.41.21.2
Bone: cortical tissue density6.68.610.7-2.82.82.83.13.33.22.62.62.82.83.1-3.12.73.3
Bone: elastic displacement0.20.20.30.4-0.4-0.4-0.4-0.5-0.6-0.2-0.3-0.3-0.4-0.40.6-0.5-0.3
Bone: elastic work0.00.00.00.0-0.1-0.0-0.10.0-0.00.20.10.0-0.1-0.20.10.00.1
Bone: endosteal estimation0.20.50.80.6-0.7-0.6-0.8-0.9-0.9-0.9-0.8-0.5-0.7-0.90.8-0.1-0.6
Bone: endosteal perimeter0.40.91.50.9-0.9-0.9-1.0-1.2-1.2-0.9-1.0-0.9-0.9-1.11.0-0.4-0.8
Bone: final force0.20.30.40.6-0.6-0.5-0.6-0.6-0.6-0.4-0.6-0.5-0.6-0.60.4-0.2-0.3
Bone: final moment0.20.30.50.6-0.6-0.6-0.7-0.7-0.7-0.5-0.6-0.6-0.6-0.70.5-0.3-0.4
Bone: marrow area0.20.40.60.5-0.5-0.5-0.6-0.7-0.7-0.7-0.7-0.3-0.5-0.80.60.0-0.5
Bone: maximum diameter0.40.71.10.9-0.9-0.8-0.9-1.0-1.0-0.9-0.9-0.7-0.9-0.90.8-0.2-0.7
Bone: maximum force0.40.81.20.9-0.9-0.9-1.0-0.9-0.9-0.7-1.0-0.9-0.9-1.10.7-0.5-0.6
Bone: maximum moment0.50.81.30.9-1.0-0.9-1.1-1.0-1.0-0.7-1.0-0.9-0.9-1.10.8-0.6-0.7
Bone: minimum diameter0.00.00.10.1-0.2-0.1-0.3-0.3-0.4-0.0-0.2-0.2-0.1-0.40.20.1-0.0
Bone: periosteal estimation0.30.61.00.8-0.8-0.8-0.9-1.0-1.0-0.8-0.9-0.7-0.8-1.00.7-0.2-0.6
Bone: periosteal perimeter0.40.61.00.7-0.7-0.7-0.9-1.0-1.0-0.6-0.7-1.0-0.7-0.90.7-0.5-0.7
Bone: post-yield work0.10.20.30.5-0.5-0.4-0.5-0.1-0.2-0.4-0.6-0.5-0.4-0.50.1-0.5-0.3
Bone: stiffness0.00.00.10.2-0.2-0.2-0.3-0.2-0.2-0.3-0.3-0.1-0.2-0.3-0.10.2-0.1
Bone: tissue strength0.10.10.40.4-0.4-0.4-0.4-0.1-0.2-0.0-0.3-0.7-0.4-0.40.4-0.3-0.1
Bone: trabecular number0.71.01.41.0-1.0-1.0-0.9-1.0-1.1-1.1-1.2-0.8-1.1-0.90.8-1.0-1.2
Bone: trabecular spacing0.00.00.3-0.10.10.10.00.00.00.60.4-0.00.10.10.10.10.3
Bone: trabecular thickness1.51.82.31.3-1.3-1.3-1.4-1.4-1.4-1.4-1.5-1.5-1.3-1.51.3-1.1-1.3
Bone: trabecular tissue density0.20.21.3-0.40.40.40.30.20.21.10.60.20.40.4-0.30.40.4
Breakpoint value in progressive ratio session4.14.65.7-2.32.32.22.22.22.12.01.72.02.32.2-2.42.02.1
Distance traveled before self-admin0.60.71.4-0.90.90.90.80.60.60.90.41.10.80.8-0.61.20.5
Distance traveled after self-admin1.11.22.51.0-1.0-1.0-1.0-0.9-0.9-1.6-1.6-0.7-1.1-1.21.5-0.4-0.9
Delta time in closed arm before/after self-admin0.10.10.5-0.10.10.10.10.50.4-0.2-0.6-0.20.10.1-0.00.70.4
Delta time in open arm before/after self-admin0.20.20.5-0.40.40.30.30.40.40.60.70.20.40.5-0.40.30.3
Diff in mean of infusions in LGA sessions0.60.61.3-0.80.80.80.91.01.00.10.10.80.80.9-1.10.60.7
Extinction: sum of active levers before priming1.11.12.1-1.01.01.11.11.11.00.80.61.01.10.9-0.91.51.5
Active lever presses in extinction session 60.10.10.40.3-0.3-0.3-0.2-0.4-0.4-0.2-0.6-0.1-0.3-0.30.5-0.5-0.3
Delta distance traveled before/after self-admin2.52.74.71.7-1.7-1.7-1.6-1.3-1.3-2.2-1.7-1.7-1.8-1.81.8-1.3-1.1
Delta ambulatory time before/after self-admin2.83.14.51.9-1.9-1.8-1.8-1.5-1.4-2.1-1.5-1.9-1.8-1.91.9-1.6-1.2
Time in closed arm before self-admin1.21.42.91.1-1.1-1.2-1.3-1.3-1.3-0.4-0.3-1.4-1.1-1.01.0-1.7-1.5
Time in closed arm after self-admin0.70.72.10.9-0.9-0.9-1.1-0.6-0.7-0.7-0.8-1.5-0.7-0.80.6-0.6-0.9
Time in open arm before self-admin0.30.31.4-0.30.30.40.50.60.7-0.1-0.10.50.30.3-0.11.21.1
Time in open arm after self-admin0.50.61.4-0.60.60.60.80.80.90.70.70.60.60.8-0.61.21.2
Sum of active levers in priming session hrs 5-63.63.65.0-2.02.02.02.11.81.71.41.32.21.91.9-1.92.02.0
Time to tail flick, vehicle, before self-admin1.81.93.5-1.31.41.31.51.41.40.80.91.41.41.5-1.91.31.4
Time to tail flick, vehicle, after self-admin0.20.30.80.4-0.4-0.4-0.4-0.2-0.2-0.5-0.6-0.6-0.4-0.30.3-0.8-0.9
Time to tail flick, test, before self-admin0.10.10.30.2-0.2-0.3-0.2-0.4-0.5-0.1-0.1-0.4-0.1-0.2-0.2-0.5-0.2
Time to tail flick, test, after self-admin0.10.10.30.3-0.3-0.3-0.3-0.0-0.2-0.6-0.6-0.3-0.3-0.4-0.0-0.2-0.3
Delta time to tail flick, vehicle, before/after SA1.71.72.71.3-1.3-1.3-1.4-1.2-1.2-0.9-1.0-1.5-1.3-1.21.4-1.5-1.6
Delta time to tail flick, test, before/after SA0.20.20.5-0.40.40.50.40.60.50.20.00.60.40.3-0.20.70.4
Ambulatory time before self-admin0.40.41.3-0.70.70.70.60.50.40.80.40.90.60.6-0.31.10.5
Ambulatory time after self-admin1.51.63.01.2-1.2-1.1-1.3-1.1-1.1-1.7-1.5-1.0-1.3-1.51.7-0.7-0.9
Total heroin consumption1.61.92.8-1.31.31.31.51.61.51.31.01.21.41.5-1.41.31.7
Area under the delay curve0.30.30.5-0.60.60.60.50.70.50.50.40.60.60.5-0.60.70.6
Delay disc. indifference point, 0s delay0.90.91.2-1.01.01.00.91.11.10.90.70.81.01.1-1.10.90.8
Delay disc. indifference point, 16s delay0.30.30.40.5-0.5-0.5-0.6-0.4-0.5-0.4-0.4-0.5-0.5-0.60.4-0.7-0.6
Delay disc. indifference point, 2s delay0.20.20.4-0.60.50.50.40.40.40.60.60.30.60.4-0.30.50.4
Delay disc. indifference point, 24s delay0.60.60.9-0.70.70.70.70.70.70.50.60.90.70.6-0.71.00.9
Delay disc. indifference point, 4s delay3.53.74.4-2.12.02.01.82.01.91.81.61.72.11.9-2.02.01.8
Delay disc. indifference point, 8s delay0.10.20.4-0.40.40.40.40.50.40.20.00.50.30.3-0.40.60.4
Delay discount exponential model param0.40.40.60.7-0.7-0.7-0.6-0.7-0.6-0.6-0.4-0.7-0.7-0.50.6-0.8-0.7
Delay discount hyperbolic model param0.70.71.00.9-0.9-0.9-0.7-0.9-0.8-0.8-0.6-0.8-0.9-0.70.8-1.0-0.9
Fecal boli incidents, locomotor time 13.13.45.01.8-1.8-1.8-1.9-1.7-1.8-1.4-1.4-2.0-1.8-1.81.7-2.2-2.2
Change in fecal boli incidents, locomotor task2.42.33.3-1.51.51.51.51.61.61.31.31.31.51.5-1.41.71.8
Time >=10cm from walls, locomotor time 10.20.20.5-0.30.40.30.50.50.5-0.10.10.50.40.5-0.50.70.7
Bouts of movement, locomotor time 10.10.10.30.2-0.2-0.2-0.2-0.2-0.20.10.5-0.3-0.2-0.30.1-0.4-0.4
Total resting periods, locomotor time 10.20.20.50.4-0.4-0.4-0.4-0.3-0.30.10.5-0.6-0.3-0.50.3-0.6-0.7
Rest time, locomotor task time 10.20.20.60.4-0.4-0.4-0.5-0.4-0.40.10.1-0.5-0.4-0.50.5-0.6-0.7
Distance moved, locomotor task time 11.01.11.5-1.11.11.11.20.91.00.30.21.21.11.1-1.01.11.2
Vertical activity count, locomotor time 10.30.30.9-0.50.50.50.60.40.5-0.3-0.10.60.50.5-0.40.81.0
Time >=10cm from walls, locomotor time 20.60.61.0-0.70.70.70.80.80.80.51.00.70.70.8-0.71.00.9
Bouts of movement, locomotor time 20.10.10.30.3-0.3-0.3-0.3-0.3-0.3-0.2-0.1-0.3-0.3-0.30.3-0.4-0.5
Total resting periods, locomotor time 20.10.10.30.4-0.4-0.4-0.4-0.3-0.3-0.2-0.1-0.4-0.4-0.30.3-0.4-0.6
Rest time, locomotor task time 21.01.21.8-1.01.01.01.11.31.21.31.00.81.01.2-1.31.00.9
Distance moved, locomotor task time 20.10.10.3-0.40.40.40.30.10.1-0.00.10.40.40.1-0.10.50.5
Vertical activity count, locomotor time 20.10.10.60.1-0.1-0.0-0.2-0.4-0.4-0.8-0.5-0.0-0.1-0.40.60.30.3
Weight adjusted by age0.91.01.8-0.90.90.90.90.90.81.11.20.71.00.9-0.91.31.4
Seeking ratio, delayed vs. immediate footshock0.30.40.70.7-0.7-0.7-0.6-0.5-0.4-0.6-0.2-0.8-0.6-0.60.2-0.8-0.7
Locomotion in novel chamber0.50.61.2-0.80.80.70.71.11.10.80.40.30.90.9-0.90.60.8
Locomotion in novel chamber post-restriction1.72.12.71.6-1.5-1.6-1.5-1.2-1.2-1.3-1.6-1.6-1.5-1.41.7-1.1-1.0
Progressive ratio0.20.21.3-0.40.40.30.20.10.21.20.5-0.00.50.5-0.7-0.4-0.3
Food seeking constrained by brief footshock0.60.71.40.8-0.8-0.8-0.7-1.0-0.9-0.8-0.9-0.4-0.9-0.90.8-1.0-1.2
Seeking ratio, punishment vs. effort0.30.31.80.4-0.4-0.3-0.1-0.1-0.2-1.3-0.90.2-0.5-0.50.70.40.3
Run reversals in cocaine runway, females0.20.20.7-0.50.50.50.40.50.40.0-0.30.60.50.3-0.20.70.8
Run reversals in cocaine runway, males0.80.81.51.1-1.1-1.2-1.0-0.8-0.9-0.5-0.7-1.2-1.1-0.81.0-0.4-0.5
Latency to leave start box in cocaine runway3.03.35.11.8-1.8-1.8-2.0-1.7-1.6-1.6-1.4-2.2-1.7-1.81.5-2.2-2.0
Latency to leave start box in cocaine runway, F4.55.07.42.3-2.3-2.3-2.5-2.0-2.0-1.7-1.7-2.7-2.2-2.32.1-2.6-2.5
Latency to leave start box in cocaine runway, M0.70.71.50.7-0.7-0.7-0.7-0.8-0.7-1.2-0.9-0.6-0.7-0.70.5-1.2-1.0
Cd content in liver0.50.60.9-0.70.70.70.80.90.90.60.70.40.80.8-0.90.50.8
Co content in liver0.10.10.60.1-0.1-0.1-0.2-0.1-0.1-0.3-0.2-0.3-0.1-0.20.1-0.7-0.4
Cu content in liver2.22.74.0-1.61.61.61.71.71.71.11.42.01.51.7-1.62.01.5
Fe content in liver1.51.72.2-1.41.31.41.21.31.31.31.31.31.41.2-1.51.21.2
K content in liver0.20.20.40.3-0.3-0.3-0.3-0.4-0.4-0.6-0.4-0.1-0.3-0.40.3-0.5-0.6
Mg content in liver0.70.70.9-0.80.80.80.80.90.80.70.80.90.80.9-0.90.80.9
Mn content in liver2.52.84.2-1.71.71.71.91.71.71.31.42.11.61.8-1.71.71.5
Na content in liver0.90.91.60.9-0.9-0.9-0.8-1.3-1.2-1.1-1.2-0.5-1.0-0.81.0-0.6-1.0
Rb content in liver0.10.10.4-0.10.10.10.20.60.60.60.50.10.10.4-0.5-0.00.2
Se content in liver0.20.31.00.5-0.5-0.5-0.5-0.6-0.5-0.2-0.5-0.6-0.4-0.40.4-1.0-0.7
Sr content in liver1.81.72.5-1.41.41.41.31.11.11.21.31.21.41.2-1.01.61.4
Zn content in liver0.10.10.10.2-0.2-0.3-0.2-0.3-0.3-0.3-0.1-0.3-0.2-0.10.3-0.3-0.1