Hub : Genes

Stxbp2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000000994 0.06 0.04 1.3e-04 0.03 0.03 0.04 0.04 3.0e-04 2.3e-04 8.2e-05 8.7e-05
2 Adipose isoform ratio ENSRNOT00000001322 0.04 0.03 8.7e-03 0.01 0.01 0.01 0.01 4.9e-02 3.3e-02 2.3e-02 4.6e-02
3 Adipose isoform ratio ENSRNOT00000107607 0.09 0.05 8.6e-06 0.04 0.03 0.03 0.03 5.6e-05 7.0e-04 4.8e-04 1.5e-04
4 BLA gene expression ENSRNOG00000000994 0.19 0.09 1.1e-05 0.13 0.12 0.09 0.12 1.6e-07 4.8e-07 2.6e-05 3.7e-07
5 BLA isoform ratio ENSRNOT00000107607 0.07 0.05 6.7e-03 0.01 0.03 0.02 0.02 9.9e-02 6.1e-03 3.0e-02 4.2e-02
6 Brain gene expression ENSRNOG00000000994 0.1 0.06 8.8e-04 0.04 0.03 0.04 0.04 8.7e-05 4.6e-04 3.4e-04 8.8e-05
7 Liver alternative polyA ENSRNOT00000001322 0.04 0.02 1.0e-03 0.01 0.02 0.02 0.01 3.5e-02 1.6e-03 2.8e-03 6.9e-03
8 Liver alternative polyA ENSRNOT00000107607 0.04 0.02 1.2e-03 0.01 0.02 0.02 0.01 3.6e-02 1.9e-03 3.6e-03 7.6e-03
9 Liver isoform ratio ENSRNOT00000107607 0.15 0.07 8.7e-11 0.09 0.08 0.08 0.09 7.7e-10 2.4e-09 1.4e-09 5.9e-10
10 Liver isoform ratio ENSRNOT00000115749 0.1 0.05 3.3e-06 0.05 0.03 0.03 0.04 6.9e-06 3.5e-04 1.9e-04 3.4e-05
11 NAcc gene expression ENSRNOG00000000994 0.1 0.06 1.7e-03 0.07 0.05 0.06 0.06 9.6e-06 2.2e-04 2.4e-05 2.7e-05
12 NAcc isoform ratio ENSRNOT00000107607 0.08 0.05 2.2e-04 0.05 0.05 0.04 0.04 6.7e-05 1.5e-04 1.2e-03 4.8e-04
13 OFC gene expression ENSRNOG00000000994 0.43 0.16 2.0e-03 0.14 0.14 0.14 0.12 2.8e-04 3.3e-04 3.1e-04 7.0e-04
14 PL gene expression ENSRNOG00000000994 0.13 0.05 1.0e-05 0.05 0.06 0.05 0.05 1.6e-04 2.6e-05 1.9e-04 7.1e-05
15 PL isoform ratio ENSRNOT00000107607 0.07 0.05 3.1e-03 0.06 0.04 0.05 0.02 2.2e-05 1.1e-03 2.1e-04 9.0e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
BMI with tail2.58.113.5-0.22.7-3.2-3.1-2.7-1.8-1.91.9-3.63.1-3.2-3.0-3.1-3.7-3.3
BMI without tail3.67.512.7-0.22.3-3.2-3.1-1.8-2.5-2.12.1-3.63.4-3.0-3.4-2.9-3.2-2.6
Body weight11.850.086.3-3.36.7-8.1-8.0-4.0-5.9-3.33.4-9.37.9-9.2-7.0-9.2-8.8-7.0
Epididymis fat weight0.30.84.10.2-0.3-0.8-0.5-1.6-0.5-0.80.8-0.50.6-0.3-0.6-0.2-0.9-2.0
Glucose0.20.22.01.4-0.1-0.4-0.2-0.20.1-0.50.50.10.10.6-0.10.50.20.5
Heart weight0.91.38.50.6-2.90.10.20.7-1.6-0.70.70.6-0.41.11.31.10.91.4
Left kidney weight6.117.434.3-2.93.0-4.6-4.6-1.4-4.5-1.81.9-5.44.5-5.9-4.0-5.8-4.9-3.7
Right kidney weight5.315.130.9-2.73.1-4.4-4.3-1.2-3.7-1.51.5-5.34.1-5.6-3.8-5.5-4.6-3.2
Tail length6.319.130.9-1.53.3-5.0-5.1-2.2-4.6-2.82.8-5.65.2-5.2-5.1-5.2-5.1-4.1
Length with tail12.144.476.1-3.46.0-7.5-7.7-3.1-6.5-3.33.4-8.57.6-8.7-6.8-8.7-8.0-6.1
Length without tail8.318.032.0-2.24.3-4.8-4.8-2.6-3.5-1.81.9-5.44.6-5.7-3.6-5.6-5.4-4.3
Liver weight, left0.81.36.7-2.60.50.20.21.20.41.6-1.6-0.5-0.3-1.50.5-1.6-0.2-0.2
Liver weight, right2.23.67.5-2.21.7-1.8-1.6-0.8-1.5-0.30.4-2.31.8-2.7-1.2-2.7-2.3-2.6
Parametrial fat weight0.20.31.0-0.50.4-0.3-0.30.90.30.7-0.7-0.50.1-1.0-0.2-0.9-0.10.6
Retroperitoneal fat weight0.41.46.22.3-0.3-0.6-0.5-2.50.6-1.11.10.10.30.8-0.60.9-0.6-1.7
Intraocular pressure0.91.23.3-1.50.9-0.6-0.9-0.8-1.2-0.40.4-1.00.9-1.4-0.9-1.4-1.4-1.8
Extensor digitorum longus weight4.216.926.7-2.13.3-4.3-4.6-3.0-4.2-2.42.5-5.04.4-4.8-4.3-4.9-5.2-4.7
Soleus weight0.92.64.5-1.91.7-1.2-1.5-1.2-1.7-0.50.5-1.71.4-2.1-1.4-2.1-2.0-2.0
Tibialis anterior weight6.321.733.8-1.74.1-5.0-5.3-3.5-4.6-3.03.0-5.75.2-5.3-5.1-5.4-5.8-5.0
Tibia length3.08.519.9-1.83.3-3.1-3.3-0.1-1.8-0.70.7-3.93.4-4.4-3.2-4.5-3.3-1.3
Number of licking bursts0.91.05.3-1.20.20.2-0.02.3-0.01.0-1.0-0.3-0.1-1.10.1-1.00.52.1
Food consumed during 24 hour testing period0.30.41.4-1.2-0.20.40.31.00.20.8-0.80.1-0.5-0.50.5-0.40.30.3
Times rat made contact with spout0.80.91.5-0.00.6-1.1-1.2-0.2-1.2-0.80.8-1.21.0-1.0-1.1-1.0-1.0-0.3
Mean time between licks in bursts1.52.13.30.4-1.31.61.80.81.30.9-0.91.8-1.71.71.61.81.71.2
Mean num. licks in bursts0.50.62.90.60.2-0.6-0.4-1.6-0.4-0.80.9-0.30.40.2-0.40.1-0.8-1.7
Std. dev. time between licks in bursts0.20.21.0-0.20.3-0.2-0.1-0.5-0.7-0.50.6-0.10.30.0-0.30.2-0.3-1.0
Water consumed over 24 hours1.01.23.9-1.60.8-0.9-1.00.7-1.00.1-0.1-1.40.8-1.9-0.8-2.0-1.00.1
Indifference point 0 sec1.01.64.6-2.10.21.21.41.21.31.9-1.90.7-1.3-0.21.5-0.10.8-0.2
Indifference point AUC0.40.41.0-0.90.1-0.7-0.60.1-0.7-0.10.1-0.90.4-1.0-0.2-1.0-0.7-0.9
Indifference point function ln k0.20.30.8-0.5-0.30.70.60.6-0.00.4-0.40.6-0.50.40.60.30.60.9
Indifference point function log k0.20.30.8-0.5-0.30.70.60.6-0.00.4-0.40.6-0.50.40.60.30.60.9
Delay discounting total patch changes 0 sec1.42.25.9-2.4-0.21.51.71.51.42.2-2.21.0-1.70.01.90.01.0-0.1
Delay discounting total patch changes 12 sec0.50.62.6-1.61.00.30.40.30.81.1-1.1-0.1-0.5-0.80.6-0.6-0.2-1.1
Delay discounting total patch changes 18 sec1.21.65.2-2.3-0.00.91.21.51.02.0-2.00.4-1.3-0.41.6-0.40.70.1
Delay discounting total patch changes 24 sec1.01.32.9-1.7-0.71.41.50.80.61.2-1.21.2-1.50.51.40.60.9-0.5
Delay discounting total patch changes 6 sec0.71.15.0-2.2-0.30.70.90.90.71.5-1.50.3-1.0-0.61.5-0.40.3-0.8
Delay discounting time to switch 0 sec0.40.64.42.10.70.1-0.1-0.81.5-0.30.20.40.20.5-0.50.70.10.5
Delay discounting water rate 0 sec0.81.310.5-3.20.00.10.11.0-1.21.0-0.9-0.6-0.1-1.30.6-1.3-0.3-1.0
Delay discounting water rate 12 sec0.20.31.1-1.1-1.00.50.50.3-0.70.1-0.10.5-0.40.20.50.30.30.1
Delay discounting water rate 18 sec0.40.51.50.4-1.20.50.3-0.5-0.9-0.90.90.8-0.20.9-0.01.10.30.1
Delay discounting water rate 24 sec0.50.62.8-1.3-0.1-0.4-0.50.0-1.7-0.30.3-0.70.8-1.1-0.4-0.9-0.7-0.5
Delay discounting water rate 6 sec0.20.31.7-1.3-0.20.30.2-0.3-0.70.1-0.00.1-0.20.00.4-0.1-0.1-1.2
Locomotor activity1.52.46.7-0.10.7-1.9-1.7-1.0-2.6-1.81.8-1.81.9-1.3-1.2-1.2-1.7-1.2
Locomotor testing distance0.20.41.5-1.20.1-0.5-0.20.3-0.80.1-0.1-0.70.4-0.90.1-0.9-0.5-0.4
Locomotor testing rearing0.40.61.3-1.1-0.40.81.10.60.71.1-1.10.6-1.00.21.10.20.60.2
Light reinforcement 10.51.04.72.2-0.9-0.4-0.3-1.1-0.4-1.41.40.20.31.2-0.91.20.10.3
Light reinforcement 20.40.51.80.0-0.50.80.61.00.70.7-0.70.7-0.60.50.40.50.91.3
Reaction time number correct0.30.52.9-1.7-0.7-0.00.20.9-0.50.7-0.7-0.2-0.5-0.40.6-0.60.1-0.0
Reaction time mean minus median3.74.810.82.40.1-2.0-2.2-3.3-2.2-3.23.2-1.22.2-0.0-2.6-0.1-1.9-2.3
Reaction time mean minus median AUC1.01.23.11.7-1.2-0.3-0.5-1.7-1.0-1.81.70.30.51.0-1.00.9-0.3-0.9
Reaction time num false alarms0.70.92.61.6-0.4-0.3-0.4-1.3-1.0-1.61.60.20.61.10.10.9-0.2-0.6
Reaction time num false alarms AUC0.50.72.01.1-0.3-0.2-0.3-1.4-0.9-1.41.40.20.60.90.30.7-0.3-1.1
Reaction time trials correct on left0.30.52.9-1.7-0.7-0.00.20.9-0.50.7-0.7-0.2-0.5-0.40.6-0.60.1-0.0
Reaction time trials on left0.30.42.6-1.6-0.8-0.00.20.8-0.60.7-0.6-0.2-0.4-0.40.6-0.60.1-0.0
Reaction time mean1.11.69.43.1-0.50.30.0-1.20.4-1.41.41.0-0.01.8-0.11.80.60.6
Reaction time mean AUC1.21.68.72.9-0.60.40.2-1.20.5-1.31.31.1-0.21.90.11.90.70.5
Median of all reaction times1.62.18.62.9-0.71.00.9-0.41.3-0.60.61.7-0.82.30.82.31.41.5
Reaction time omissions0.60.92.71.6-1.30.1-0.1-1.2-0.3-1.21.20.70.11.2-0.01.40.2-0.0
Reaction time false alarm rate0.81.13.21.80.1-0.3-0.5-1.8-0.7-1.71.70.20.80.9-0.20.8-0.5-1.0
Reaction time premature initiation rate0.30.51.31.00.1-0.5-0.6-0.8-0.8-1.11.1-0.20.80.1-0.70.4-0.4-0.1
Reaction time premature initiations0.10.20.80.2-0.3-0.4-0.4-0.4-0.9-0.70.7-0.30.5-0.1-0.40.1-0.3-0.1
Std. dev. reaction times1.52.16.32.5-0.3-0.8-1.1-2.3-0.9-2.32.2-0.11.10.8-1.40.7-0.8-1.1
Reaction time trials completed0.30.42.6-1.6-0.8-0.00.20.8-0.60.7-0.6-0.2-0.4-0.40.6-0.60.1-0.0
Reaction time trials AUC0.30.42.4-1.6-0.90.10.40.8-0.40.7-0.7-0.0-0.6-0.20.8-0.30.3-0.1
Social response proportion5.86.310.30.81.8-3.0-3.1-1.4-3.2-2.62.6-2.93.2-2.3-3.0-2.2-2.7-1.0
Social responses1.51.95.0-0.50.9-1.4-1.5-1.0-2.2-1.41.4-1.51.5-1.3-1.1-1.3-1.5-1.4
Social time1.52.05.21.9-1.41.31.10.20.5-0.50.51.8-1.02.10.62.31.51.9
Conditioned locomotion0.30.31.1-1.00.30.70.6-0.10.80.8-0.80.4-0.5-0.20.5-0.20.1-0.5
Cocaine response after cond. corrected0.40.42.2-0.11.5-0.3-0.3-0.11.00.5-0.5-0.50.3-0.8-0.3-0.8-0.5-0.7
Cocaine response after cond. not corrected0.60.72.60.31.5-0.5-0.6-1.10.5-0.20.2-0.70.6-0.7-0.6-0.6-0.9-1.6
Cocaine response before conditioning0.91.14.30.6-0.1-0.5-0.6-2.1-1.2-1.51.6-0.20.70.3-0.70.4-0.9-1.7
Saline control response0.70.92.4-1.5-0.0-0.8-0.80.6-1.5-0.10.1-1.10.8-1.4-0.8-1.5-0.8-0.2
Condit. Reinf. active minus inactive responses2.32.86.01.00.1-2.2-2.1-1.3-2.5-2.12.1-1.81.9-0.9-1.9-1.0-1.6-0.7
Condit. Reinf. active-inactive response ratio1.61.73.71.5-0.4-1.6-1.5-0.8-1.9-1.91.9-1.11.4-0.2-1.4-0.3-0.90.2
Condit. Reinf. active responses2.73.77.00.90.4-2.4-2.3-2.0-2.6-2.42.4-1.92.1-0.9-2.1-1.0-2.0-1.8
Condit. Reinf. inactive responses0.60.73.4-0.40.5-0.8-0.7-1.1-0.9-0.60.7-0.80.6-0.5-0.6-0.6-1.0-1.8
Condit. Reinf. lever presses0.60.82.50.10.1-1.0-0.9-1.4-1.1-1.01.1-0.80.6-0.2-0.6-0.3-1.0-1.6
Condit. Reinf. lever reinforcers received2.13.06.31.10.0-2.1-2.0-1.8-2.5-2.32.4-1.61.8-0.5-1.8-0.6-1.6-1.4
Pavlov. Cond. lever latency1.11.43.5-1.71.01.11.01.71.51.9-1.90.4-0.7-0.70.8-0.70.61.0
Pavlov. Cond. magazine entry latency1.11.25.62.4-0.6-0.4-0.4-1.6-0.4-1.61.60.40.31.4-0.31.4-0.0-0.6
Pavlov. Cond. change in total contacts0.50.71.71.2-1.3-0.5-0.5-0.9-1.1-1.31.30.00.20.9-0.30.9-0.10.0
Pavlov. Cond. index score1.01.23.92.0-1.2-0.5-0.4-1.5-1.0-1.71.70.30.21.4-0.31.3-0.1-0.5
Pavlov. Cond. latency score0.91.13.71.9-1.0-0.4-0.4-1.5-0.8-1.61.60.30.21.3-0.31.3-0.1-0.6
Pavlov. Cond. lever contacts0.91.23.61.5-0.7-0.9-0.8-1.9-1.2-1.71.7-0.20.50.7-0.60.7-0.6-1.2
Pavlov. Cond. magazine entry number0.91.24.5-2.11.2-0.00.01.00.41.3-1.3-0.80.2-1.8-0.2-1.7-0.5-0.2
Pavlov. Cond. intertrial magazine entries0.20.20.7-0.80.2-0.4-0.30.4-0.70.0-0.0-0.60.4-0.8-0.4-0.8-0.4-0.3
Pavlov. Cond. lever-magazine prob. diff.1.01.34.32.1-1.2-0.4-0.4-1.4-1.0-1.71.70.40.21.5-0.21.40.0-0.4
Pavlov. Cond. response bias1.21.74.32.1-1.3-0.7-0.6-2.0-1.2-1.91.90.20.41.4-0.41.4-0.3-1.1
Conditioned reinforcement - actives2.72.75.1-0.81.6-1.9-2.0-0.1-2.3-1.01.0-2.02.1-1.5-1.7-2.0-1.7-1.1
Conditioned reinforcement - inactives0.30.31.2-1.00.50.40.31.10.10.7-0.70.0-0.0-0.00.5-0.40.30.8
Conditioned locomotion1.61.94.2-0.91.2-1.4-1.6-0.7-2.0-1.01.0-1.41.9-1.1-1.3-1.4-1.5-1.7
Intermittent access intake day 1-15 change0.70.73.1-1.81.2-0.1-0.11.1-0.20.8-0.8-0.60.1-1.00.1-1.2-0.20.0
Intermittent access intake escalation0.50.52.1-1.51.3-0.3-0.30.6-0.50.4-0.4-0.70.3-0.9-0.1-1.1-0.4-0.4
Intermittent access intake escalation 20.30.20.9-0.90.50.60.50.70.20.6-0.60.3-0.50.10.5-0.10.30.2
Intermitt. access day 1 inactive lever presses0.80.82.4-1.5-0.00.90.91.50.31.1-1.10.5-0.4-0.11.0-0.20.71.6
Intermitt. access day 15 inactive lever presses0.60.72.6-0.80.90.60.70.91.61.3-1.30.2-0.1-0.30.6-0.40.40.6
Intermitt. access escalation Index0.30.30.90.3-0.60.20.4-0.3-0.4-0.30.30.6-0.80.80.51.00.5-0.3
Intermittent access day 1 total infusions0.70.83.61.4-1.00.50.5-0.6-0.1-0.70.71.0-0.51.90.41.40.70.3
Intermittent access day 15 total infusions0.10.10.7-0.30.10.40.30.2-0.20.0-0.00.4-0.40.90.50.30.3-0.1
Intermittent access terminal intake (last 3 days)0.20.21.10.1-0.20.60.50.20.40.2-0.20.7-0.71.00.50.60.50.2
Intermittent access total infusions0.40.42.41.0-0.40.30.2-0.50.1-0.50.50.6-0.31.50.20.90.3-0.1
Intermittent access day 1 locomotion1.51.65.91.6-1.50.90.8-1.20.3-0.80.81.5-0.82.40.82.00.8-0.5
Intermittent access day 15 total locomotion0.50.62.10.5-0.60.40.3-0.8-0.9-0.90.90.70.11.40.41.10.2-0.7
Intermittent access total locomotion1.21.45.71.5-1.20.80.6-1.1-0.3-1.11.11.3-0.42.40.71.90.7-0.3
Intermittent access standard deviation0.80.82.8-1.70.60.50.41.21.11.5-1.5-0.1-0.3-0.60.5-1.00.10.4
Cocaine induced anxiety0.40.41.90.7-0.30.30.2-1.2-0.1-0.60.60.5-0.10.90.10.9-0.0-1.4
Post-drug Anxiety1.41.56.52.5-1.20.50.6-1.20.5-0.90.91.2-0.42.10.32.10.80.1
Baseline Anxiety1.11.25.42.3-1.10.40.60.01.2-0.20.10.9-0.51.50.31.41.01.7
Lifetime Intake0.30.31.71.0-0.40.20.1-0.40.4-0.30.30.5-0.31.30.20.70.3-0.0
Incentive Sensitization - Responses0.20.20.60.4-0.10.10.2-0.1-0.7-0.50.50.4-0.20.80.20.70.3-0.2
Incentive Sensitization - Breakpoint0.20.20.70.4-0.10.10.2-0.2-0.7-0.50.50.4-0.30.80.20.70.3-0.2
Progressive ratio test 1 active lever presses0.20.20.3-0.20.6-0.5-0.60.2-0.6-0.30.3-0.50.4-0.0-0.4-0.5-0.30.1
Progressive ratio test 1 breakpoint0.20.30.5-0.10.6-0.7-0.70.2-0.6-0.40.4-0.70.5-0.2-0.6-0.6-0.40.2
Progressive ratio test 1 inactive lever presses0.20.21.0-1.00.4-0.1-0.00.8-0.70.2-0.2-0.20.3-0.20.1-0.50.00.8
Progressive ratio test 2 active lever presses0.50.52.30.10.5-0.8-0.9-0.2-1.5-0.91.0-0.70.80.0-0.7-0.4-0.6-0.4
Progressive ratio test 2 breakpoint0.40.42.00.50.2-0.6-0.7-0.1-1.4-1.01.0-0.30.60.4-0.50.1-0.2-0.0
Progressive ratio test 2 inactive lever presses0.50.54.1-2.00.70.0-0.10.8-1.00.4-0.4-0.40.3-0.50.3-0.9-0.3-0.2
Total sessions with >9 infusions0.10.10.30.4-0.1-0.4-0.5-0.5-0.3-0.50.5-0.30.30.3-0.5-0.0-0.3-0.4
Short access day 1 total inactive lever presses0.20.30.7-0.50.30.60.50.90.40.6-0.60.4-0.30.10.50.00.50.8
Short access day 10 total inactive lever presses1.01.15.4-2.31.2-0.1-0.10.90.21.1-1.1-0.90.6-1.6-0.0-1.7-0.6-0.3
Short access day 1 total infusions1.01.13.40.0-0.81.01.00.71.91.2-1.21.1-1.30.91.00.71.00.6
Short access day 10 total infusions0.50.52.10.6-0.60.70.7-0.20.80.2-0.20.8-0.91.50.71.00.7-0.1
Short access total infusions0.20.21.10.8-0.40.1-0.00.01.00.2-0.20.2-0.20.7-0.00.20.30.4
Short access day 1 locomotion0.91.04.12.0-1.10.40.2-0.6-0.1-1.01.00.90.01.70.11.50.60.6
Short access day 10 total locomotion0.80.81.7-0.2-1.31.11.20.11.00.6-0.61.1-1.11.21.10.90.80.1
Short access total locomotion0.60.62.21.2-1.10.50.4-0.60.6-0.30.30.8-0.21.50.41.10.50.2
Compulsive drug intake3.13.15.00.8-1.61.82.01.31.41.0-1.12.1-2.12.01.92.12.22.2
One hour access (0.3 mA shock)0.60.71.7-0.6-0.50.90.81.1-0.30.4-0.40.9-0.91.31.10.71.00.8
One hour access (shock baseline)0.70.92.8-0.40.8-0.9-1.0-0.6-1.7-1.01.0-0.81.0-0.2-0.8-0.7-0.9-1.3
Number of responses in last shaping day0.10.10.2-0.4-0.20.30.20.40.00.3-0.30.2-0.40.40.30.10.30.2
Context. condit. distance diff. score4.45.38.7-0.32.0-2.5-2.5-2.5-2.6-2.02.0-2.52.4-2.0-2.4-2.0-2.8-3.0
Locomotion velocity, session 10.30.41.31.1-1.1-0.10.1-0.4-0.2-0.60.60.4-0.10.90.10.90.30.1
Locomotion distance, session 11.01.23.01.0-1.61.01.00.30.60.0-0.01.4-1.11.71.11.61.31.1
Locomotion velocity, session 20.30.31.41.1-1.2-0.10.00.3-0.2-0.50.50.20.00.6-0.00.60.51.1
Locomotion distance, session 21.41.94.30.9-2.11.41.41.00.50.2-0.21.6-1.41.91.42.01.81.4
Locomotion velocity, session 30.40.51.20.10.9-0.7-0.6-1.0-0.6-0.70.8-0.70.7-0.3-0.7-0.3-0.8-1.1
Locomotion distance, session 30.30.40.9-0.80.60.90.70.40.40.6-0.60.5-0.80.40.80.20.50.0
Stereotopy head waving bouts, day 31.31.54.9-1.60.8-1.0-1.1-0.2-0.60.1-0.1-1.51.2-2.2-1.2-2.1-1.4-0.8
Stereotopy head waving duration, day 30.10.10.2-0.3-0.5-0.2-0.00.10.30.3-0.3-0.10.1-0.5-0.1-0.4-0.10.2
Locomotion velocity, session 70.91.04.32.10.6-0.9-0.9-0.9-0.9-1.51.5-0.40.70.7-0.70.3-0.30.2
Locomotion distance, session 70.50.71.81.30.9-0.4-0.6-0.8-1.1-1.31.3-0.10.50.7-0.50.4-0.1-0.5
Stereotopy head waving bouts, day 70.60.73.40.5-1.80.70.80.00.50.0-0.01.0-0.81.20.81.20.80.5
Stereotopy head waving duration, day 70.50.72.50.6-1.60.60.70.30.60.2-0.20.9-0.71.10.71.10.90.8
Locomotion velocity, session 80.50.61.10.90.3-1.0-0.8-0.6-0.8-1.01.0-0.90.9-0.3-0.9-0.2-0.7-0.0
Locomotion distance, session 81.31.92.70.21.3-1.6-1.6-1.3-1.6-1.41.4-1.61.5-1.0-1.5-1.1-1.6-1.3
Degree of sensitization distance0.60.63.41.8-0.7-0.1-0.1-0.1-0.4-0.90.90.50.11.1-0.11.00.50.8
Degree of sensitization stereotypy0.30.41.20.8-1.10.40.4-0.20.3-0.20.20.7-0.41.00.41.00.50.2
Condit. Reinf. active minus inactive responses0.20.31.01.0-0.30.10.3-0.60.4-0.40.40.4-0.20.90.20.90.3-0.2
Condit. Reinf. active-inactive response ratio0.30.31.21.00.3-0.4-0.3-1.1-0.0-0.70.7-0.10.40.4-0.30.4-0.4-0.6
Condit. Reinf. active responses0.30.41.20.8-0.90.20.4-0.60.1-0.50.50.6-0.31.00.41.10.4-0.2
Condit. Reinf. inactive responses0.70.82.60.7-1.60.70.9-0.10.0-0.30.31.1-0.81.40.81.50.90.5
Incentive salience index mean0.30.41.20.7-0.50.40.5-0.70.3-0.30.30.7-0.51.10.51.10.4-0.5
Condit. Reinf. lever presses0.30.31.00.3-0.40.50.4-0.80.0-0.40.40.7-0.51.00.51.00.3-0.7
Time in familiar zone, hab. session 11.21.12.5-0.90.61.41.21.01.61.5-1.50.9-1.00.11.00.20.80.4
Time in novel zone, hab. session 10.90.91.80.50.2-1.3-1.1-0.8-1.2-1.11.1-1.11.0-0.5-1.0-0.6-1.0-0.4
Total zone transitions, hab. session 10.91.33.91.7-1.80.70.7-0.20.2-0.60.61.3-0.82.00.81.91.10.4
Total locomotion distance, hab. session 10.40.51.71.3-0.90.10.1-1.00.1-0.70.70.6-0.21.20.21.10.2-0.7
Locomotion velocity, hab. session 10.81.13.31.7-1.50.50.4-0.90.3-0.80.81.1-0.51.80.51.70.7-0.2
Time in familiar zone, hab. session 20.10.10.4-0.10.50.1-0.1-0.20.40.2-0.2-0.20.2-0.4-0.2-0.3-0.3-0.6
Time in novel zone, hab. session 20.30.30.90.6-0.60.20.30.1-0.2-0.30.30.6-0.41.00.41.00.60.8
Total zone transitions, hab. session 20.10.10.40.4-0.5-0.3-0.40.5-0.6-0.40.4-0.20.4-0.1-0.4-0.20.10.6
Total locomotion distance, hab. session 20.20.20.90.6-0.90.30.10.1-0.1-0.30.30.5-0.20.70.20.60.40.3
Locomotion velocity, hab. session 20.20.21.10.6-1.00.30.20.3-0.1-0.20.20.5-0.20.70.20.60.50.4
Novel to familiar place preference ratio0.20.21.90.6-0.5-0.3-0.20.5-0.3-0.20.2-0.00.00.3-0.00.20.41.4
Novelty place preference0.30.32.30.8-0.8-0.10.10.6-0.1-0.10.10.3-0.20.60.20.50.61.5
Time in novel zone, NPP test0.20.21.80.7-0.6-0.2-0.10.4-0.2-0.20.20.1-0.00.40.00.30.41.3
Total zone transitions, NPP test0.10.20.50.5-0.6-0.3-0.4-0.3-0.7-0.70.7-0.20.40.2-0.40.0-0.2-0.2
Total locomotion distance, NPP test0.60.92.61.3-0.7-0.5-0.7-1.6-0.8-1.41.4-0.10.60.6-0.60.5-0.6-1.2
Locomotion velocity, NPP test0.60.92.11.1-1.1-0.4-0.7-1.4-1.0-1.41.4-0.00.60.6-0.60.5-0.5-1.1
Pavlov. Cond. lever latency1.41.85.4-1.60.3-1.6-1.30.3-1.00.1-0.1-1.71.2-2.2-1.3-2.3-1.4-0.6
Pavlov. Cond. magazine entry latency0.40.51.70.21.3-0.3-0.5-0.6-0.6-0.80.8-0.60.7-0.3-0.7-0.1-0.6-0.8
Pavlov. Cond. change in total contacts0.60.62.81.70.5-0.2-0.5-1.3-0.1-1.21.2-0.00.50.6-0.50.6-0.4-0.7
Pavlov. Cond. index score0.30.41.10.81.00.1-0.1-0.9-0.1-0.80.80.00.30.5-0.20.6-0.3-0.8
Pavlov. Cond. latency score0.30.41.31.10.90.3-0.0-1.0-0.0-0.90.90.20.10.8-0.10.9-0.1-0.6
Pavlov. Cond. lever contacts0.81.03.21.3-0.21.10.9-0.50.8-0.30.31.2-0.81.70.91.80.90.3
Pavlov. Cond. magazine entry number0.70.92.4-0.2-1.00.60.81.11.11.1-1.20.7-0.90.40.90.21.01.5
Pavlov. Cond. intertrial magazine entries1.21.42.1-0.0-1.21.31.40.91.00.8-0.81.4-1.41.31.41.41.51.1
Pavlov. Cond. lever-magazine prob. diff.0.30.31.80.61.30.2-0.1-0.90.0-0.60.6-0.00.20.3-0.20.5-0.3-0.8
Pavlov. Cond. response bias0.30.41.10.51.0-0.2-0.4-1.0-0.5-0.90.9-0.30.50.0-0.50.2-0.6-1.0
Bone: apparent density2.74.511.3-3.42.8-1.7-1.3-0.7-0.90.6-0.6-2.51.2-3.1-1.3-3.1-2.3-2.8
Bone surface4.07.113.5-2.63.4-2.6-2.3-1.4-1.5-0.30.3-3.32.3-3.6-2.4-3.7-3.2-3.5
Bone volume2.54.210.6-2.73.3-1.5-1.3-1.1-0.60.4-0.4-2.31.3-2.8-1.4-2.8-2.3-3.1
Bone: connectivity density4.16.513.3-3.02.8-2.6-2.2-0.9-1.9-0.20.2-3.42.2-3.6-2.2-3.7-3.0-2.9
Bone: cortical apparent density0.30.32.21.50.5-0.2-0.2-0.50.0-0.70.70.10.20.7-0.20.70.10.5
Bone: cortical area3.04.66.70.12.3-2.3-2.5-2.1-2.0-1.81.8-2.42.4-2.0-2.4-2.0-2.6-2.4
Bone: cortical porosity0.00.00.2-0.40.40.10.10.20.10.2-0.20.0-0.0-0.20.1-0.2-0.00.3
Bone: cortical porosity0.10.10.30.2-0.20.40.4-0.1-0.0-0.10.10.6-0.30.50.40.50.30.4
Bone: cortical thickness2.44.06.10.02.5-2.1-2.3-1.7-1.8-1.61.6-2.32.3-2.0-2.3-2.0-2.4-2.0
Bone: cortical thickness1.01.22.4-0.21.4-1.2-1.2-0.5-1.5-1.01.0-1.31.2-1.1-1.3-1.1-1.2-0.6
Bone: cortical tissue density0.20.31.91.40.4-0.00.0-0.30.2-0.60.50.30.00.7-0.00.80.30.6
Bone: elastic displacement0.20.30.8-0.80.4-0.5-0.40.1-0.40.1-0.1-0.70.4-0.8-0.3-0.9-0.6-0.1
Bone: elastic work2.33.06.6-1.91.9-1.7-1.7-0.6-1.5-0.30.4-2.21.6-2.5-1.6-2.6-2.1-1.5
Bone: endosteal estimation0.40.84.1-2.00.7-0.3-0.30.6-0.50.7-0.7-0.80.2-1.4-0.2-1.4-0.5-0.6
Bone: endosteal perimeter0.51.13.1-1.20.8-0.8-0.9-0.8-1.3-0.50.5-1.00.8-1.1-0.8-1.1-1.2-1.8
Bone: final force2.43.96.2-0.52.0-2.2-2.4-0.8-2.0-1.21.2-2.52.3-2.4-2.4-2.4-2.2-1.1
Bone: final moment1.93.15.1-0.61.9-2.0-2.1-0.5-1.8-1.01.0-2.32.0-2.2-2.1-2.3-2.0-0.9
Bone: marrow area0.40.84.4-2.10.7-0.2-0.20.7-0.50.8-0.7-0.70.2-1.3-0.1-1.3-0.4-0.5
Bone: maximum diameter1.42.54.5-1.22.1-1.4-1.6-1.0-1.2-0.50.6-1.81.5-2.0-1.5-2.0-1.9-2.0
Bone: maximum force1.73.05.1-1.12.0-1.8-1.9-0.7-1.8-0.80.8-2.21.9-2.2-1.9-2.3-2.0-1.6
Bone: maximum moment1.32.34.4-1.21.8-1.5-1.6-0.5-1.5-0.50.5-1.91.6-2.0-1.6-2.1-1.7-1.3
Bone: minimum diameter0.00.00.1-0.20.00.10.10.2-0.00.1-0.10.1-0.1-0.00.2-0.00.10.2
Bone: periosteal estimation1.32.64.4-1.31.8-1.6-1.7-0.8-1.6-0.70.7-1.91.6-2.1-1.6-2.1-1.9-1.7
Bone: periosteal perimeter1.32.25.6-0.11.0-1.4-1.5-1.9-1.8-1.51.5-1.31.4-0.9-1.4-0.9-1.7-2.4
Bone: post-yield work0.30.53.5-0.90.8-0.3-0.2-0.7-0.20.0-0.0-0.50.2-0.5-0.2-0.6-0.6-1.9
Bone: stiffness0.81.32.80.20.9-1.1-1.4-1.0-1.7-1.31.3-1.11.3-0.8-1.3-0.8-1.2-1.0
Bone: tissue strength1.21.22.8-1.5-0.11.01.01.41.21.7-1.70.5-1.1-0.11.1-0.20.80.8
Bone: trabecular number2.94.69.2-2.42.9-2.1-1.8-0.9-1.4-0.10.1-2.81.8-3.0-1.8-3.0-2.5-2.3
Bone: trabecular spacing2.53.25.91.2-2.02.01.90.71.70.7-0.72.4-1.92.31.82.42.11.6
Bone: trabecular thickness4.14.99.9-2.02.8-2.2-1.9-1.6-1.6-0.60.6-2.71.9-2.8-2.0-2.8-2.7-3.1
Bone: trabecular tissue density2.94.19.93.00.7-1.8-2.0-2.6-2.2-3.13.1-1.12.10.2-2.10.2-1.5-1.1
Breakpoint value in progressive ratio session1.51.74.11.30.2-1.1-1.2-2.0-1.3-1.81.8-0.81.3-0.1-1.2-0.2-1.3-1.8
Distance traveled before self-admin0.60.62.41.5-1.5-0.10.1-0.7-0.4-1.01.00.40.30.90.01.20.30.1
Distance traveled after self-admin0.20.21.40.4-1.2-0.4-0.2-0.3-0.7-0.60.6-0.10.20.3-0.00.3-0.00.1
Delta time in closed arm before/after self-admin0.30.30.70.60.4-0.3-0.2-0.3-0.8-0.80.8-0.20.80.3-0.40.3-0.1-0.3
Delta time in open arm before/after self-admin1.61.62.90.6-1.71.31.3-0.01.60.6-0.71.5-1.71.51.51.41.10.8
Diff in mean of infusions in LGA sessions0.20.21.5-0.0-0.1-0.2-0.1-0.8-0.5-0.50.5-0.10.10.1-0.10.1-0.4-1.2
Extinction: sum of active levers before priming0.50.51.41.2-1.20.30.3-0.80.3-0.50.50.7-0.31.10.41.10.30.0
Active lever presses in extinction session 60.20.10.7-0.20.0-0.3-0.3-0.5-0.3-0.20.2-0.50.2-0.3-0.3-0.3-0.5-0.9
Delta distance traveled before/after self-admin0.20.20.8-0.90.20.1-0.00.7-0.10.5-0.5-0.2-0.3-0.30.2-0.60.00.7
Delta ambulatory time before/after self-admin0.30.30.6-0.6-0.20.50.40.60.40.6-0.60.3-0.70.30.7-0.10.40.8
Time in closed arm before self-admin0.70.82.3-1.51.1-0.7-0.60.7-0.80.4-0.4-0.90.3-1.5-0.6-1.4-0.6-0.1
Time in closed arm after self-admin0.20.31.8-0.60.3-0.4-0.20.4-1.3-0.30.3-0.30.5-0.4-0.5-0.2-0.1-0.0
Time in open arm before self-admin0.20.20.60.60.1-0.3-0.4-0.3-0.7-0.80.8-0.30.80.1-0.4-0.0-0.3-0.0
Time in open arm after self-admin0.00.10.30.2-0.00.2-0.1-0.40.60.1-0.10.0-0.10.10.2-0.1-0.2-0.3
Sum of active levers in priming session hrs 5-60.30.31.20.9-0.1-0.2-0.2-1.10.6-0.40.4-0.00.40.2-0.20.2-0.4-1.1
Time to tail flick, vehicle, before self-admin0.70.74.62.1-0.3-0.7-0.5-0.7-0.1-1.21.2-0.10.60.7-0.60.80.00.5
Time to tail flick, vehicle, after self-admin0.30.31.21.1-0.7-0.4-0.1-0.4-0.4-0.80.70.1-0.00.60.00.70.20.2
Time to tail flick, test, before self-admin0.60.51.5-0.60.7-0.9-0.90.1-0.8-0.10.1-1.10.6-1.0-0.6-1.2-0.8-0.1
Time to tail flick, test, after self-admin0.40.40.80.50.9-0.8-0.7-0.6-0.1-0.40.4-0.70.8-0.5-0.7-0.5-0.7-0.5
Delta time to tail flick, vehicle, before/after SA0.50.51.1-0.4-0.80.70.80.30.40.6-0.60.8-1.10.60.90.60.70.1
Delta time to tail flick, test, before/after SA0.20.20.60.20.30.50.4-0.40.80.2-0.20.5-0.10.30.30.40.2-0.5
Ambulatory time before self-admin0.91.02.41.5-1.0-0.4-0.3-1.6-0.8-1.51.50.10.70.7-0.51.0-0.2-1.0
Ambulatory time after self-admin0.20.31.10.6-1.0-0.4-0.3-0.8-0.5-0.80.8-0.10.20.4-0.10.3-0.2-0.3
Total heroin consumption1.72.06.02.1-1.81.01.0-1.40.4-1.01.01.6-1.12.50.92.30.9-0.1
Area under the delay curve1.31.46.52.5-0.5-0.6-0.7-1.5-0.4-1.91.90.00.91.0-0.81.1-0.30.2
Delay disc. indifference point, 0s delay2.32.54.52.11.7-1.7-1.9-1.6-0.7-1.91.9-1.42.1-0.6-2.1-0.4-1.5-0.3
Delay disc. indifference point, 16s delay0.40.42.11.4-0.4-0.2-0.2-0.6-0.2-1.01.00.20.30.7-0.30.80.10.3
Delay disc. indifference point, 2s delay1.71.98.22.9-0.5-0.3-0.5-2.3-0.0-2.02.00.40.81.4-0.71.7-0.4-0.7
Delay disc. indifference point, 24s delay0.50.51.81.3-0.70.30.2-0.10.3-0.60.60.6-0.01.00.21.00.51.2
Delay disc. indifference point, 4s delay0.90.94.02.0-0.2-0.2-0.4-1.60.1-1.41.40.40.61.0-0.40.9-0.3-0.3
Delay disc. indifference point, 8s delay0.60.62.41.5-1.0-0.1-0.1-0.8-0.3-1.11.10.40.20.9-0.21.10.10.3
Delay discount exponential model param1.41.56.5-2.60.80.50.61.60.41.9-1.9-0.2-0.7-1.20.6-1.30.2-0.1
Delay discount hyperbolic model param1.31.46.4-2.50.70.40.51.60.31.8-1.8-0.3-0.7-1.20.6-1.40.2-0.1
Fecal boli incidents, locomotor time 11.01.13.0-0.50.1-1.2-1.2-0.6-1.7-0.90.9-1.21.4-1.0-1.1-0.7-1.0-0.9
Change in fecal boli incidents, locomotor task0.50.51.80.10.20.50.60.71.40.8-0.80.5-0.90.30.5-0.00.61.3
Time >=10cm from walls, locomotor time 10.60.62.01.4-0.20.20.1-1.40.5-0.70.70.5-0.11.3-0.11.20.0-0.3
Bouts of movement, locomotor time 10.80.91.6-0.70.9-0.9-1.0-0.2-1.2-0.50.5-1.30.8-1.1-0.6-1.2-1.0-1.2
Total resting periods, locomotor time 10.70.81.6-0.60.8-0.9-1.0-0.4-1.2-0.60.6-1.20.9-1.0-0.7-1.0-1.0-1.2
Rest time, locomotor task time 10.60.71.8-0.41.0-0.8-0.9-0.6-0.8-0.40.5-0.90.7-0.9-0.9-0.8-1.0-1.3
Distance moved, locomotor task time 10.30.41.40.8-1.20.20.20.1-0.1-0.30.30.6-0.20.80.30.80.61.0
Vertical activity count, locomotor time 10.10.10.50.2-0.5-0.2-0.20.1-0.7-0.50.5-0.20.2-0.1-0.1-0.1-0.00.2
Time >=10cm from walls, locomotor time 21.92.04.00.71.5-1.7-1.5-2.0-0.7-1.31.3-1.41.7-0.9-1.6-0.8-1.8-1.6
Bouts of movement, locomotor time 20.91.02.1-0.91.0-0.6-0.9-0.8-1.1-0.50.6-1.00.9-1.1-0.7-1.3-1.2-1.5
Total resting periods, locomotor time 20.80.92.0-1.01.3-0.5-0.8-0.6-0.9-0.30.3-0.90.7-1.2-0.6-1.4-1.2-1.4
Rest time, locomotor task time 20.10.10.30.0-0.00.20.3-0.40.30.0-0.00.3-0.50.60.20.30.1-0.6
Distance moved, locomotor task time 20.20.32.1-0.2-0.2-0.0-0.11.1-0.10.3-0.3-0.1-0.0-0.40.0-0.10.31.4
Vertical activity count, locomotor time 20.80.92.4-1.20.5-0.8-0.81.0-1.10.1-0.0-1.20.9-1.5-0.7-1.4-0.60.3
Weight adjusted by age0.60.72.6-1.61.4-0.1-0.20.5-0.00.8-0.8-0.60.1-1.3-0.3-1.5-0.6-0.4
Seeking ratio, delayed vs. immediate footshock3.33.85.3-0.3-1.32.22.22.22.01.9-2.02.1-2.31.52.11.52.32.3
Locomotion in novel chamber0.10.20.7-0.5-0.70.20.20.7-0.8-0.00.00.10.10.20.40.10.30.3
Locomotion in novel chamber post-restriction1.41.64.7-0.6-0.5-1.3-1.4-0.6-2.2-1.11.2-1.31.6-1.3-1.1-1.3-1.3-1.4
Progressive ratio0.91.11.70.0-0.21.21.31.01.20.9-0.91.2-0.71.01.31.01.31.3
Food seeking constrained by brief footshock2.73.25.4-1.4-0.22.32.31.62.32.3-2.31.8-2.10.82.20.91.80.8
Seeking ratio, punishment vs. effort0.30.41.1-1.00.4-0.3-0.4-0.1-0.10.3-0.3-0.60.0-1.0-0.4-1.0-0.6-0.8
Run reversals in cocaine runway, females0.40.41.0-0.1-0.30.50.80.20.60.5-0.50.7-1.00.60.70.70.70.2
Run reversals in cocaine runway, males0.80.71.5-0.6-1.01.10.91.20.30.7-0.71.0-0.90.61.00.51.10.9
Latency to leave start box in cocaine runway0.20.31.31.2-0.0-0.5-0.4-0.1-0.2-0.50.5-0.30.50.1-0.7-0.0-0.10.8
Latency to leave start box in cocaine runway, F0.30.40.80.20.6-0.8-0.60.5-0.00.1-0.1-0.80.8-0.8-0.7-0.9-0.40.6
Latency to leave start box in cocaine runway, M0.80.82.91.0-1.70.40.6-0.5-0.4-0.70.71.0-0.41.40.31.40.60.4
Cd content in liver3.53.86.1-0.2-2.52.22.11.71.11.2-1.22.2-2.32.12.32.12.32.3
Co content in liver0.91.02.9-1.7-0.60.70.81.70.51.5-1.50.4-0.9-0.40.9-0.40.71.0
Cu content in liver0.50.62.2-0.9-0.60.80.80.30.50.8-0.80.7-1.10.41.50.40.6-0.5
Fe content in liver2.12.58.7-0.61.4-1.2-1.4-2.0-1.8-1.31.4-1.41.3-1.2-1.3-1.2-1.9-2.9
K content in liver0.20.21.30.10.3-0.4-0.2-0.6-0.2-0.20.2-0.40.2-0.20.1-0.2-0.4-1.2
Mg content in liver0.40.40.7-0.30.8-0.7-0.6-0.2-0.6-0.20.3-0.90.6-0.8-0.3-0.8-0.7-0.7
Mn content in liver0.70.81.60.0-0.40.71.01.31.01.0-1.00.6-1.00.70.90.71.11.2
Na content in liver0.60.60.90.50.9-0.9-0.8-0.9-0.7-0.80.8-0.80.8-0.5-0.9-0.5-0.9-0.8
Rb content in liver1.41.85.10.7-2.31.21.5-0.21.10.5-0.51.7-1.51.71.71.71.2-0.3
Se content in liver3.64.313.20.92.5-2.1-1.8-3.0-1.5-2.02.0-1.91.8-1.0-1.6-1.0-2.3-3.6
Sr content in liver1.11.03.2-1.6-0.20.70.51.80.91.6-1.60.2-0.6-0.60.2-0.60.61.3
Zn content in liver1.61.75.3-2.31.5-0.8-0.80.6-0.50.8-0.8-1.60.7-2.2-0.8-2.2-1.2-0.6