Hub : Genes

N4bp2l2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative polyA ENSRNOT00000001468 0.04 0.03 4.1e-03 0 0.01 0.01 0 1.7e-01 6.8e-02 7.2e-02 1.1e-01
2 Adipose alternative polyA ENSRNOT00000111844 0.07 0.04 3.1e-04 0.02 0 -0 0 4.2e-03 1.6e-01 6.0e-01 7.4e-02
3 Adipose alternative polyA ENSRNOT00000111844 0.14 0.07 1.2e-14 0.12 0.1 0.1 0.11 7.1e-13 2.2e-11 1.3e-11 4.6e-12
4 Adipose alternative polyA ENSRNOT00000118063 0.14 0.07 5.1e-15 0.12 0.1 0.1 0.11 3.9e-13 1.1e-11 1.8e-11 2.6e-12
5 Adipose isoform ratio ENSRNOT00000001468 0.05 0.04 2.3e-04 0.01 0.02 0.01 0.01 3.7e-02 6.1e-03 1.3e-02 4.0e-02
6 IL mRNA stability ENSRNOG00000001108 0.16 0.1 8.8e-03 0.06 0.07 0.06 0.08 1.2e-02 8.7e-03 1.8e-02 4.7e-03
7 Liver alternative polyA ENSRNOT00000111844 0.06 0.04 1.3e-04 0.02 0.02 0.01 0.02 1.5e-03 3.3e-03 1.8e-02 6.3e-03
8 Liver alternative polyA ENSRNOT00000111844 0.1 0.05 2.7e-10 0.04 0.07 0.06 0.07 1.3e-05 2.3e-08 1.1e-07 8.8e-08
9 Liver alternative polyA ENSRNOT00000118063 0.1 0.05 1.6e-10 0.04 0.07 0.06 0.07 1.5e-05 1.5e-08 9.9e-08 7.2e-08
10 Liver isoform ratio ENSRNOT00000111844 0.04 0.03 9.4e-03 0.01 0 0 0 6.7e-02 2.3e-01 8.0e-02 2.3e-01
11 Liver intron excision ratio chr12:104159:105321 0.03 0.02 9.1e-03 0 0 0.01 0 1.1e-01 8.5e-02 5.7e-02 1.1e-01
12 Liver mRNA stability ENSRNOG00000001108 0.03 0.02 1.5e-03 0.02 0.01 0.01 0.01 2.0e-03 2.4e-02 2.2e-02 1.1e-02
13 PL mRNA stability ENSRNOG00000001108 0.05 0.03 1.9e-03 0.04 0.04 0.03 0.04 2.7e-04 1.0e-03 1.3e-03 8.8e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
BMI with tail1.96.211.32.7-2.62.7-2.71.53.11.62.1-2.1-2.63.42.8-1.3
BMI without tail2.55.310.02.0-1.02.5-2.51.63.21.92.7-2.7-0.92.72.4-2.6
Body weight13.958.880.48.2-4.88.9-8.97.07.96.98.4-8.4-4.77.89.0-7.2
Epididymis fat weight0.20.41.20.3-0.50.6-0.6-0.00.90.80.4-0.4-0.50.81.1-0.2
Glucose0.40.51.2-0.4-0.7-0.60.6-1.10.1-1.1-0.90.9-0.70.4-0.21.1
Heart weight0.91.35.7-1.42.4-0.30.3-0.30.11.10.6-0.62.4-1.1-0.1-0.9
Left kidney weight9.928.542.05.0-1.56.1-6.15.34.86.56.4-6.4-1.44.26.4-5.8
Right kidney weight7.521.330.84.7-1.75.3-5.34.74.34.95.6-5.5-1.73.85.4-4.8
Tail length6.820.531.34.0-1.35.1-5.13.95.24.25.6-5.6-1.24.35.0-5.6
Length with tail15.456.577.97.4-3.28.7-8.77.07.77.38.8-8.8-3.36.98.7-8.2
Length without tail10.623.233.85.3-3.45.7-5.74.44.74.35.1-5.1-3.44.85.8-4.1
Liver weight, left1.21.95.61.9-0.41.4-1.42.4-0.31.91.4-1.4-0.4-0.01.6-1.3
Liver weight, right3.66.09.12.5-0.62.8-2.82.81.83.03.0-3.0-0.51.62.8-2.8
Parametrial fat weight0.30.61.81.3-1.20.6-0.60.90.10.50.4-0.4-1.20.61.0-0.3
Retroperitoneal fat weight0.93.06.9-0.1-2.6-0.90.9-2.00.4-2.0-1.91.9-2.61.5-0.62.5
Intraocular pressure1.62.27.61.00.41.4-1.41.40.92.81.7-1.70.40.61.6-2.0
Extensor digitorum longus weight4.518.126.43.8-1.14.8-4.83.84.44.95.1-5.1-1.23.74.9-4.8
Soleus weight1.23.55.91.70.02.2-2.22.21.42.02.4-2.4-0.11.02.0-2.4
Tibialis anterior weight6.221.229.24.2-1.85.3-5.33.85.24.65.4-5.4-1.94.65.4-4.9
Tibia length4.813.418.74.3-2.84.3-4.33.63.43.03.8-3.8-2.83.74.2-3.1
Number of licking bursts0.80.92.61.00.31.0-1.01.60.01.11.2-1.20.3-0.10.7-1.4
Food consumed during 24 hour testing period0.30.41.30.70.10.6-0.61.1-0.50.70.6-0.50.1-0.40.7-0.6
Times rat made contact with spout0.60.71.40.6-0.01.0-1.00.61.00.81.1-1.2-0.00.80.8-1.2
Mean time between licks in bursts1.62.23.0-1.40.9-1.71.7-1.2-1.6-1.4-1.61.70.9-1.6-1.71.4
Mean num. licks in bursts0.10.10.4-0.3-0.3-0.20.2-0.60.3-0.2-0.30.3-0.30.40.10.3
Std. dev. time between licks in bursts0.30.41.4-0.51.20.0-0.0-0.10.30.70.5-0.51.2-0.3-0.1-0.7
Water consumed over 24 hours2.53.04.71.60.12.0-2.02.20.82.22.1-2.10.10.62.0-2.2
Indifference point 0 sec0.30.52.00.50.40.2-0.21.3-1.40.80.3-0.20.4-1.10.3-0.5
Indifference point AUC0.60.61.40.40.60.7-0.71.00.31.11.1-1.10.6-0.10.5-1.2
Indifference point function ln k0.40.51.8-0.71.3-0.40.40.0-0.70.5-0.00.01.3-1.1-0.3-0.5
Indifference point function log k0.40.51.8-0.71.3-0.40.40.0-0.70.5-0.00.01.3-1.1-0.3-0.5
Delay discounting total patch changes 0 sec0.40.73.00.40.80.0-0.01.4-1.70.80.2-0.10.8-1.50.1-0.5
Delay discounting total patch changes 12 sec0.30.41.40.8-0.10.5-0.51.2-0.60.70.6-0.5-0.1-0.30.5-0.6
Delay discounting total patch changes 18 sec0.40.52.30.70.30.3-0.31.5-1.30.60.5-0.40.3-1.10.1-0.5
Delay discounting total patch changes 24 sec1.01.23.8-0.61.9-0.40.40.7-1.40.80.3-0.31.9-1.8-0.4-0.7
Delay discounting total patch changes 6 sec0.50.82.60.70.60.6-0.61.6-1.01.20.7-0.70.6-0.90.7-0.9
Delay discounting time to switch 0 sec2.74.114.31.0-3.8-0.20.2-1.20.5-2.4-1.61.6-3.82.0-0.12.6
Delay discounting water rate 0 sec2.64.19.00.42.71.2-1.22.5-0.42.72.3-2.32.7-1.50.9-3.0
Delay discounting water rate 12 sec0.91.34.7-0.82.2-0.10.10.4-0.51.40.6-0.62.2-1.4-0.3-1.1
Delay discounting water rate 18 sec0.91.24.4-1.72.1-0.80.8-0.9-0.20.5-0.20.22.1-1.0-0.8-0.2
Delay discounting water rate 24 sec1.62.25.40.41.51.1-1.11.50.72.31.9-1.91.6-0.21.0-2.1
Delay discounting water rate 6 sec0.50.72.1-0.21.40.3-0.30.7-0.10.60.8-0.81.5-0.8-0.1-1.4
Locomotor activity2.13.39.0-0.11.81.4-1.40.72.03.02.2-2.31.80.71.4-2.6
Locomotor testing distance0.91.43.80.31.20.9-0.91.10.51.91.4-1.41.2-0.10.9-1.9
Locomotor testing rearing0.20.31.0-0.30.8-0.30.30.3-0.90.2-0.20.20.8-1.0-0.3-0.1
Light reinforcement 10.81.54.2-1.80.6-1.41.4-2.10.0-1.0-1.31.20.6-0.2-1.41.0
Light reinforcement 20.10.20.3-0.30.3-0.30.3-0.2-0.6-0.5-0.40.40.3-0.6-0.40.3
Reaction time number correct0.70.92.1-0.01.40.3-0.31.1-0.51.40.8-0.81.4-1.00.5-1.4
Reaction time mean minus median0.70.93.9-1.30.4-0.40.4-1.82.00.60.0-0.10.41.2-0.00.1
Reaction time mean minus median AUC1.11.43.9-2.01.4-1.41.4-1.90.40.4-0.70.61.4-0.4-0.90.5
Reaction time num false alarms0.81.13.1-1.71.4-1.11.1-1.60.4-0.4-0.60.51.4-0.3-1.00.3
Reaction time num false alarms AUC0.50.61.9-1.41.2-0.80.8-1.20.5-0.1-0.30.31.2-0.2-0.60.1
Reaction time trials correct on left0.70.92.1-0.01.40.3-0.31.1-0.51.40.8-0.81.4-1.00.5-1.4
Reaction time trials on left0.60.92.0-0.01.40.3-0.31.0-0.51.40.8-0.81.4-1.00.5-1.4
Reaction time mean2.23.08.0-1.9-0.3-2.02.0-2.80.0-1.6-2.02.0-0.30.0-1.72.2
Reaction time mean AUC2.53.38.3-2.10.0-2.22.2-2.9-0.2-1.6-2.12.10.0-0.2-1.92.3
Median of all reaction times3.24.38.4-2.0-0.5-2.42.4-2.9-0.7-2.2-2.62.5-0.5-0.4-2.22.8
Reaction time omissions0.70.92.9-1.20.1-1.21.2-1.70.4-0.9-1.01.00.10.0-1.11.1
Reaction time false alarm rate0.40.62.4-1.20.4-0.80.8-1.60.8-0.7-0.60.50.40.4-0.70.6
Reaction time premature initiation rate0.10.10.7-0.40.20.0-0.0-0.60.90.20.2-0.20.20.70.10.0
Reaction time premature initiations0.20.20.7-0.40.70.1-0.1-0.10.50.90.5-0.50.80.20.3-0.6
Std. dev. reaction times0.71.04.3-1.40.1-1.11.1-2.11.1-0.1-0.80.70.10.7-0.60.9
Reaction time trials completed0.60.92.0-0.01.40.3-0.31.0-0.51.40.8-0.81.4-1.00.5-1.4
Reaction time trials AUC0.60.92.5-0.31.60.0-0.00.8-0.71.20.6-0.61.6-1.20.2-1.2
Social response proportion4.85.211.31.4-0.62.4-2.41.03.42.82.6-2.7-0.62.62.6-2.2
Social responses1.62.05.30.31.11.2-1.20.91.62.31.8-1.91.10.61.0-1.9
Social time2.73.56.4-2.51.5-2.32.3-2.5-0.9-1.3-1.91.91.5-1.3-1.91.7
Conditioned locomotion0.10.10.30.5-0.20.2-0.20.6-0.40.20.1-0.1-0.2-0.20.6-0.0
Cocaine response after cond. corrected1.72.07.21.8-2.71.1-1.10.70.3-0.5-0.10.1-2.71.51.30.7
Cocaine response after cond. not corrected1.31.45.21.4-2.31.0-1.00.20.7-0.5-0.10.1-2.31.61.00.7
Cocaine response before conditioning0.50.61.7-1.11.3-0.40.4-0.90.70.40.1-0.21.3-0.1-0.8-0.4
Saline control response2.33.17.90.61.51.5-1.51.80.82.82.2-2.21.5-0.11.5-2.5
Condit. Reinf. active minus inactive responses1.11.33.80.00.40.9-0.9-0.02.01.91.3-1.30.41.21.2-1.2
Condit. Reinf. active-inactive response ratio0.50.52.2-0.50.50.3-0.3-0.51.51.00.6-0.70.50.80.3-0.6
Condit. Reinf. active responses1.11.64.4-0.10.51.0-1.0-0.12.12.11.4-1.40.51.31.3-1.3
Condit. Reinf. inactive responses0.30.41.50.10.30.6-0.60.40.61.20.8-0.80.30.40.9-0.8
Condit. Reinf. lever presses0.20.21.1-0.20.40.2-0.2-0.10.61.10.4-0.40.40.30.5-0.4
Condit. Reinf. lever reinforcers received0.81.13.6-0.50.80.6-0.6-0.41.81.91.0-1.10.81.01.0-1.1
Pavlov. Cond. lever latency0.50.72.11.4-0.90.8-0.81.5-0.70.00.4-0.3-0.9-0.10.9-0.2
Pavlov. Cond. magazine entry latency1.41.75.3-1.60.2-1.41.4-2.30.3-1.1-1.51.40.20.2-1.21.6
Pavlov. Cond. change in total contacts0.50.82.1-1.51.3-0.90.9-1.20.30.5-0.40.31.3-0.4-0.70.2
Pavlov. Cond. index score1.11.54.1-1.91.1-1.41.4-2.00.2-0.3-1.01.01.1-0.3-1.20.9
Pavlov. Cond. latency score1.01.33.9-1.80.9-1.31.3-2.00.2-0.4-1.01.00.9-0.2-1.11.0
Pavlov. Cond. lever contacts0.40.62.1-1.30.6-0.80.8-1.50.6-0.1-0.50.50.60.1-0.70.5
Pavlov. Cond. magazine entry number1.72.15.22.0-0.91.8-1.82.30.20.91.5-1.5-0.90.51.4-1.4
Pavlov. Cond. intertrial magazine entries0.40.51.50.40.50.7-0.70.90.30.61.0-1.00.5-0.00.6-1.2
Pavlov. Cond. lever-magazine prob. diff.1.31.64.5-2.01.2-1.51.5-2.10.2-0.4-1.11.01.2-0.4-1.30.9
Pavlov. Cond. response bias1.11.54.6-2.01.1-1.41.4-2.10.4-0.5-1.00.91.1-0.2-1.30.8
Conditioned reinforcement - actives4.14.18.31.20.52.1-2.11.81.92.92.6-2.60.61.12.2-2.6
Conditioned reinforcement - inactives0.40.41.10.50.50.5-0.51.1-0.21.00.8-0.80.5-0.40.6-0.8
Conditioned locomotion2.53.05.41.10.41.9-1.91.61.82.32.3-2.30.41.12.0-2.0
Intermittent access intake day 1-15 change1.11.12.80.90.50.9-0.91.70.01.21.4-1.30.5-0.20.8-1.5
Intermittent access intake escalation1.01.02.30.60.80.8-0.81.40.21.21.4-1.30.9-0.20.6-1.5
Intermittent access intake escalation 20.40.41.1-0.31.0-0.30.30.4-0.70.20.2-0.21.0-1.0-0.4-0.6
Intermitt. access day 1 inactive lever presses0.50.51.60.60.50.6-0.61.3-0.41.10.8-0.80.5-0.50.6-0.4
Intermitt. access day 15 inactive lever presses0.91.03.61.5-1.90.6-0.60.8-0.4-0.5-0.30.3-1.90.60.70.9
Intermitt. access escalation Index0.90.81.6-1.21.2-1.01.0-0.7-0.4-0.3-0.40.41.2-1.0-1.3-0.1
Intermittent access day 1 total infusions0.91.02.3-1.50.9-1.01.0-1.5-0.3-0.8-1.00.90.9-0.5-1.10.9
Intermittent access day 15 total infusions0.30.41.7-0.71.3-0.20.20.0-0.30.40.2-0.21.3-0.7-0.3-0.3
Intermittent access terminal intake (last 3 days)0.40.40.7-0.80.8-0.60.6-0.5-0.7-0.4-0.50.50.9-0.7-0.70.2
Intermittent access total infusions0.50.51.2-1.00.5-0.70.7-1.1-0.2-0.7-0.80.70.5-0.3-0.70.8
Intermittent access day 1 locomotion1.71.73.9-1.70.5-1.41.4-2.0-0.4-1.4-1.51.50.5-0.5-1.31.4
Intermittent access day 15 total locomotion0.40.41.4-0.91.2-0.20.2-0.50.50.10.3-0.41.2-0.1-0.3-0.7
Intermittent access total locomotion0.91.12.8-1.60.9-1.11.1-1.70.0-0.9-0.90.90.9-0.4-1.10.6
Intermittent access standard deviation0.60.62.11.4-0.80.9-0.91.4-0.50.20.5-0.5-0.80.10.9-0.4
Cocaine induced anxiety0.40.51.1-0.90.3-0.90.9-1.1-0.1-0.4-0.70.70.3-0.3-0.70.6
Post-drug Anxiety3.03.37.7-1.9-0.2-2.02.0-2.8-0.4-2.1-2.32.3-0.2-0.3-1.92.3
Baseline Anxiety2.62.76.6-1.0-1.1-1.31.3-2.1-0.4-2.6-2.22.2-1.10.2-1.52.3
Lifetime Intake0.40.51.0-0.7-0.1-0.60.6-1.0-0.2-0.9-0.90.9-0.1-0.0-0.60.9
Incentive Sensitization - Responses0.70.72.5-1.21.6-0.70.7-0.6-0.20.3-0.10.01.6-0.9-0.7-0.1
Incentive Sensitization - Breakpoint0.80.82.9-1.31.7-0.80.8-0.6-0.20.3-0.00.01.7-1.0-0.8-0.1
Progressive ratio test 1 active lever presses0.50.51.00.50.10.8-0.80.60.71.00.9-0.90.10.60.9-0.8
Progressive ratio test 1 breakpoint0.50.50.90.50.00.8-0.80.60.81.00.9-0.9-0.00.70.9-0.8
Progressive ratio test 1 inactive lever presses1.01.13.00.31.00.8-0.81.10.31.71.3-1.31.0-0.21.0-1.3
Progressive ratio test 2 active lever presses0.91.02.3-0.21.20.7-0.70.41.01.51.3-1.31.20.20.8-1.4
Progressive ratio test 2 breakpoint0.60.71.9-0.61.40.3-0.3-0.00.81.20.9-0.91.4-0.00.3-1.0
Progressive ratio test 2 inactive lever presses2.32.66.30.71.41.3-1.32.00.42.52.1-2.11.4-0.41.4-2.1
Total sessions with >9 infusions0.00.00.2-0.0-0.20.1-0.1-0.20.40.00.0-0.0-0.20.40.10.3
Short access day 1 total inactive lever presses0.10.10.40.5-0.20.4-0.40.6-0.10.40.3-0.3-0.20.00.4-0.1
Short access day 10 total inactive lever presses2.32.55.92.2-0.91.8-1.82.40.51.51.8-1.7-0.90.81.8-1.0
Short access day 1 total infusions1.11.12.20.0-1.0-0.80.8-0.5-1.3-1.4-1.41.5-1.0-0.5-0.91.5
Short access day 10 total infusions0.91.01.6-1.10.4-1.11.1-1.1-1.0-0.9-1.21.20.4-0.9-1.01.3
Short access total infusions0.70.71.70.1-1.3-0.20.2-0.7-0.2-1.2-1.01.0-1.30.5-0.31.2
Short access day 1 locomotion0.91.03.0-1.1-0.1-1.01.0-1.70.2-1.2-1.21.1-0.10.2-0.91.1
Short access day 10 total locomotion0.30.30.6-0.2-0.2-0.50.5-0.3-0.7-0.7-0.70.8-0.3-0.4-0.30.7
Short access total locomotion0.90.92.1-0.6-0.7-0.70.7-1.3-0.2-1.3-1.31.2-0.70.2-0.61.5
Compulsive drug intake3.43.44.9-1.81.0-2.22.2-1.6-2.1-1.5-2.12.11.0-2.0-2.01.8
One hour access (0.3 mA shock)1.41.66.0-1.32.4-0.70.70.1-0.91.00.3-0.32.5-1.8-0.6-0.8
One hour access (shock baseline)1.11.32.7-0.11.40.8-0.80.60.91.61.5-1.51.40.00.7-1.6
Number of responses in last shaping day0.10.10.30.20.10.3-0.30.4-0.00.50.3-0.30.1-0.20.4-0.6
Context. condit. distance diff. score2.53.15.71.1-0.11.9-1.91.12.42.22.2-2.2-0.11.81.7-2.1
Locomotion velocity, session 10.60.71.5-1.10.5-1.01.0-1.2-0.1-0.9-0.80.80.5-0.3-0.80.7
Locomotion distance, session 11.92.43.9-1.81.1-2.02.0-1.6-1.1-1.6-1.51.51.1-1.3-1.81.2
Locomotion velocity, session 20.20.30.8-0.90.6-0.50.5-0.80.0-0.4-0.40.40.6-0.3-0.20.3
Locomotion distance, session 22.23.15.4-2.32.3-1.91.9-1.5-1.4-1.0-1.31.32.3-2.1-1.90.8
Locomotion velocity, session 30.10.10.40.0-0.00.2-0.2-0.00.70.10.4-0.4-0.00.4-0.0-0.4
Locomotion distance, session 30.20.30.9-0.40.8-0.30.30.1-0.80.2-0.10.20.8-1.0-0.5-0.1
Stereotopy head waving bouts, day 32.83.45.02.0-0.62.1-2.12.21.22.12.2-2.2-0.61.22.0-2.1
Stereotopy head waving duration, day 30.20.30.70.7-0.70.5-0.50.60.10.60.3-0.3-0.70.50.8-0.2
Locomotion velocity, session 70.70.82.8-1.0-0.3-0.80.8-1.70.7-1.0-0.80.8-0.30.7-0.70.9
Locomotion distance, session 70.50.71.8-1.31.0-0.90.9-1.30.5-0.1-0.40.31.0-0.2-1.00.2
Stereotopy head waving bouts, day 70.60.71.4-1.20.9-0.90.9-1.0-0.80.1-0.90.90.9-0.9-0.50.8
Stereotopy head waving duration, day 70.50.60.9-0.90.4-0.90.9-0.9-0.7-0.2-1.01.00.4-0.6-0.40.9
Locomotion velocity, session 80.20.20.90.1-0.30.3-0.3-0.30.9-0.40.3-0.3-0.30.9-0.1-0.2
Locomotion distance, session 80.50.82.20.40.00.9-0.90.31.50.71.2-1.20.01.10.5-1.1
Degree of sensitization distance0.90.92.4-1.40.6-1.21.2-1.60.1-0.5-0.90.90.6-0.2-1.00.8
Degree of sensitization stereotypy0.40.40.9-0.90.4-0.70.7-1.0-0.4-0.0-0.80.80.4-0.4-0.30.8
Condit. Reinf. active minus inactive responses0.40.51.3-0.7-0.3-0.40.4-1.1-0.2-0.8-1.01.0-0.3-0.0-0.51.1
Condit. Reinf. active-inactive response ratio0.30.30.8-0.2-0.7-0.00.0-0.90.4-0.4-0.60.6-0.70.6-0.10.8
Condit. Reinf. active responses0.50.61.3-1.20.7-0.70.7-1.1-0.3-0.5-0.80.80.7-0.6-0.70.7
Condit. Reinf. inactive responses1.51.83.5-1.91.9-1.41.4-1.2-0.8-0.8-0.90.91.9-1.5-1.40.5
Incentive salience index mean0.50.71.3-1.10.5-0.80.8-1.2-0.5-0.6-1.01.00.5-0.6-0.80.9
Condit. Reinf. lever presses0.60.81.6-1.31.1-1.01.0-0.9-0.5-0.3-0.70.71.1-0.9-1.00.4
Time in familiar zone, hab. session 10.40.41.10.7-0.9-0.20.20.5-1.0-0.7-0.50.5-0.9-0.3-0.40.6
Time in novel zone, hab. session 10.40.41.10.10.00.7-0.7-0.01.00.90.6-0.70.00.81.0-0.6
Total zone transitions, hab. session 11.92.65.2-2.31.6-1.81.8-2.1-0.8-1.5-1.51.51.6-1.2-1.71.3
Total locomotion distance, hab. session 10.50.72.0-1.20.4-0.90.9-1.4-0.2-0.7-1.01.00.4-0.3-0.61.0
Locomotion velocity, hab. session 11.42.04.2-1.90.9-1.61.6-2.1-0.5-1.2-1.61.50.9-0.7-1.41.5
Time in familiar zone, hab. session 20.50.51.80.8-1.40.3-0.30.20.2-0.9-0.10.1-1.40.7-0.20.4
Time in novel zone, hab. session 20.70.71.8-1.31.3-0.80.8-0.9-0.40.2-0.50.51.3-0.9-0.30.2
Total zone transitions, hab. session 20.10.10.4-0.30.70.1-0.1-0.10.40.20.3-0.40.7-0.10.1-0.5
Total locomotion distance, hab. session 20.20.30.8-0.90.8-0.50.5-0.7-0.20.0-0.40.40.8-0.5-0.40.3
Locomotion velocity, hab. session 20.20.30.8-0.90.9-0.50.5-0.6-0.20.1-0.30.30.9-0.6-0.30.2
Novel to familiar place preference ratio0.10.10.3-0.40.5-0.10.1-0.30.00.5-0.10.10.5-0.10.00.0
Novelty place preference0.20.20.5-0.70.6-0.40.4-0.6-0.20.2-0.40.40.6-0.3-0.30.3
Time in novel zone, NPP test0.10.10.3-0.50.5-0.20.2-0.4-0.00.4-0.20.20.5-0.1-0.10.2
Total zone transitions, NPP test0.10.10.4-0.60.7-0.20.2-0.40.40.20.1-0.10.7-0.1-0.1-0.2
Total locomotion distance, NPP test0.20.31.4-1.00.5-0.40.4-1.20.60.1-0.30.30.50.2-0.20.3
Locomotion velocity, NPP test0.30.51.5-1.21.1-0.40.4-1.10.60.4-0.10.11.1-0.1-0.20.0
Pavlov. Cond. lever latency2.63.35.12.1-0.72.1-2.12.31.21.82.2-2.2-0.71.31.9-2.1
Pavlov. Cond. magazine entry latency0.10.10.5-0.10.20.2-0.2-0.10.7-0.10.4-0.50.20.30.1-0.5
Pavlov. Cond. change in total contacts0.50.61.9-0.6-0.7-0.50.5-1.40.5-0.8-0.90.8-0.70.6-0.41.1
Pavlov. Cond. index score0.20.20.8-0.60.1-0.50.5-0.90.3-0.6-0.50.50.10.1-0.30.5
Pavlov. Cond. latency score0.40.61.6-1.00.2-0.80.8-1.30.1-1.0-0.80.80.2-0.1-0.70.8
Pavlov. Cond. lever contacts1.72.03.5-1.60.3-1.61.6-1.9-0.8-1.5-1.81.80.3-0.8-1.41.7
Pavlov. Cond. magazine entry number0.20.30.90.2-0.5-0.30.30.1-0.9-0.6-0.70.7-0.5-0.3-0.40.7
Pavlov. Cond. intertrial magazine entries1.11.32.0-1.20.9-1.21.2-0.8-1.4-1.0-1.21.20.9-1.4-1.30.9
Pavlov. Cond. lever-magazine prob. diff.0.10.10.5-0.4-0.2-0.30.3-0.70.2-0.5-0.40.4-0.20.1-0.10.5
Pavlov. Cond. response bias0.00.10.3-0.30.2-0.00.0-0.40.50.10.1-0.10.20.20.1-0.1
Bone: apparent density3.96.512.43.1-1.12.9-2.93.51.22.33.0-2.9-1.11.32.9-2.8
Bone surface5.29.113.13.6-1.93.5-3.53.42.32.43.3-3.3-1.92.63.6-2.9
Bone volume3.25.49.23.0-1.72.7-2.72.91.31.92.4-2.4-1.71.72.8-2.1
Bone: connectivity density5.38.413.33.2-0.93.4-3.43.62.22.23.6-3.6-0.92.03.0-3.5
Bone: cortical apparent density0.40.61.6-0.7-0.3-0.80.8-1.20.2-1.0-0.90.8-0.30.3-0.60.9
Bone: cortical area1.92.85.61.5-1.21.9-1.90.92.40.91.8-1.8-1.22.31.8-1.5
Bone: cortical porosity0.10.10.40.3-0.00.4-0.40.4-0.00.70.3-0.3-0.0-0.10.3-0.3
Bone: cortical porosity0.20.20.5-0.60.7-0.30.3-0.4-0.30.3-0.30.30.7-0.6-0.40.2
Bone: cortical thickness1.62.65.11.5-1.21.9-1.91.02.30.51.7-1.8-1.22.21.6-1.5
Bone: cortical thickness0.91.12.10.50.31.1-1.10.71.21.41.4-1.40.30.80.8-1.5
Bone: cortical tissue density0.50.61.5-0.7-0.2-0.90.9-1.2-0.0-1.0-0.90.9-0.20.1-0.71.0
Bone: elastic displacement0.40.40.90.7-0.10.8-0.80.90.40.40.9-0.8-0.10.30.6-0.9
Bone: elastic work3.64.77.02.1-0.52.6-2.62.51.62.32.6-2.6-0.51.42.5-2.5
Bone: endosteal estimation0.91.94.41.30.31.4-1.42.00.22.11.7-1.60.30.11.4-1.8
Bone: endosteal perimeter0.71.54.00.70.61.1-1.11.20.82.01.6-1.60.60.41.2-1.6
Bone: final force2.74.46.31.9-0.92.4-2.41.72.32.32.4-2.4-0.92.12.5-2.1
Bone: final moment2.23.75.21.8-0.92.2-2.21.62.02.02.2-2.2-0.91.92.3-1.9
Bone: marrow area0.91.94.31.30.41.4-1.42.00.12.11.7-1.60.4-0.01.4-1.8
Bone: maximum diameter1.52.83.91.8-0.92.0-2.01.81.51.61.9-1.9-0.91.52.0-1.7
Bone: maximum force2.13.75.51.7-0.52.2-2.21.91.82.32.3-2.3-0.51.62.2-2.2
Bone: maximum moment1.83.14.51.7-0.52.0-2.01.81.52.02.1-2.1-0.51.42.0-2.0
Bone: minimum diameter0.00.00.00.00.1-0.00.00.2-0.2-0.10.1-0.10.1-0.2-0.1-0.1
Bone: periosteal estimation1.63.24.91.7-0.42.0-2.01.91.61.92.2-2.2-0.41.42.0-2.1
Bone: periosteal perimeter0.50.92.00.30.30.8-0.80.41.41.11.2-1.30.30.90.8-1.3
Bone: post-yield work0.20.20.40.40.00.5-0.50.70.20.60.6-0.60.00.10.6-0.6
Bone: stiffness0.50.71.60.10.50.8-0.80.31.31.11.1-1.20.50.70.6-1.2
Bone: tissue strength0.30.21.10.7-0.20.2-0.21.0-1.10.1-0.00.1-0.2-0.70.20.0
Bone: trabecular number4.06.29.12.9-1.12.9-2.93.01.82.22.9-2.9-1.11.82.9-2.7
Bone: trabecular spacing3.14.05.9-1.90.6-2.42.4-2.0-1.9-2.1-2.42.40.6-1.6-2.42.2
Bone: trabecular thickness4.55.47.52.5-1.12.7-2.72.61.92.42.7-2.7-1.11.82.7-2.5
Bone: trabecular tissue density0.70.94.2-1.0-0.2-0.10.1-1.92.00.8-0.10.1-0.21.60.10.3
Breakpoint value in progressive ratio session0.20.31.6-0.3-0.10.2-0.2-0.71.3-0.00.2-0.2-0.10.9-0.1-0.1
Distance traveled before self-admin0.30.31.4-0.90.1-0.50.5-1.20.3-0.5-0.50.50.20.3-0.60.6
Distance traveled after self-admin0.20.20.8-0.80.7-0.20.2-0.50.00.1-0.00.00.9-0.3-0.50.3
Delta time in closed arm before/after self-admin0.10.10.6-0.30.60.0-0.0-0.30.7-0.00.3-0.30.30.2-0.2-0.4
Delta time in open arm before/after self-admin3.12.94.4-1.60.5-1.91.9-1.6-1.9-1.9-2.12.10.5-1.6-2.01.7
Diff in mean of infusions in LGA sessions0.20.31.3-0.61.2-0.20.2-0.2-0.10.40.1-0.10.9-0.7-0.3-0.1
Extinction: sum of active levers before priming1.41.42.3-1.50.8-1.41.4-1.5-0.6-1.0-1.31.30.7-0.9-1.31.2
Active lever presses in extinction session 60.00.00.10.10.00.1-0.10.20.2-0.20.3-0.30.1-0.2-0.2-0.2
Delta distance traveled before/after self-admin0.30.31.0-0.21.0-0.10.10.4-0.50.50.2-0.21.0-0.9-0.2-0.2
Delta ambulatory time before/after self-admin0.40.41.1-0.60.8-0.60.6-0.1-0.9-0.1-0.40.40.9-1.1-0.60.4
Time in closed arm before self-admin1.51.75.10.90.51.3-1.31.70.42.31.6-1.60.6-0.01.6-1.3
Time in closed arm after self-admin1.21.23.8-0.01.50.6-0.60.80.71.91.4-1.41.4-0.30.7-1.2
Time in open arm before self-admin0.10.20.60.0-0.10.3-0.3-0.20.8-0.00.3-0.4-0.10.8-0.1-0.6
Time in open arm after self-admin0.20.20.7-0.1-0.5-0.30.3-0.4-0.4-0.9-0.70.7-0.5-0.0-0.60.4
Sum of active levers in priming session hrs 5-60.70.71.80.1-1.2-0.30.3-0.70.2-1.3-0.80.8-1.30.5-0.51.0
Time to tail flick, vehicle, before self-admin0.80.82.6-0.8-0.6-0.50.5-1.60.5-1.0-1.01.0-0.60.5-0.61.5
Time to tail flick, vehicle, after self-admin0.40.51.2-1.10.7-0.80.8-1.00.1-0.3-0.50.50.7-0.5-0.70.1
Time to tail flick, test, before self-admin0.60.61.00.8-0.50.9-0.90.90.50.81.0-1.0-0.30.70.7-1.0
Time to tail flick, test, after self-admin0.60.72.70.9-1.60.5-0.50.10.8-0.40.1-0.1-1.51.20.50.2
Delta time to tail flick, vehicle, before/after SA0.70.71.7-0.91.1-0.90.9-0.2-1.0-0.2-0.40.51.2-1.3-0.8-0.2
Delta time to tail flick, test, before/after SA0.30.20.60.1-0.7-0.20.2-0.3-0.2-0.7-0.60.6-0.70.1-0.10.8
Ambulatory time before self-admin0.30.31.4-1.00.5-0.40.4-1.20.8-0.0-0.20.10.50.4-0.30.2
Ambulatory time after self-admin0.30.30.9-1.00.7-0.50.5-0.80.0-0.1-0.30.30.9-0.2-0.60.3
Total heroin consumption4.25.08.9-2.91.3-2.72.7-3.0-1.1-2.2-2.42.41.3-1.4-2.71.8
Area under the delay curve0.80.93.9-1.1-0.3-0.80.8-2.01.0-0.6-0.90.9-0.30.8-0.41.2
Delay disc. indifference point, 0s delay2.83.010.11.4-3.21.0-1.0-0.52.1-0.50.2-0.2-3.23.01.00.4
Delay disc. indifference point, 16s delay0.50.51.8-1.10.5-0.70.7-1.40.3-0.0-0.70.70.5-0.1-0.20.8
Delay disc. indifference point, 2s delay1.82.06.0-1.0-1.2-1.21.2-2.50.9-1.5-1.51.5-1.21.2-0.71.9
Delay disc. indifference point, 24s delay0.50.51.6-0.90.2-0.70.7-1.30.0-0.5-0.80.80.2-0.1-0.51.0
Delay disc. indifference point, 4s delay0.80.92.4-0.5-1.1-0.60.6-1.50.8-1.0-0.90.9-1.11.0-0.51.1
Delay disc. indifference point, 8s delay0.70.72.1-1.30.8-0.90.9-1.40.3-0.2-0.70.60.8-0.1-0.51.0
Delay discount exponential model param1.01.14.71.4-0.11.0-1.02.2-0.80.61.0-1.0-0.1-0.50.6-1.3
Delay discount hyperbolic model param1.01.14.61.30.21.0-1.02.1-0.80.71.1-1.10.2-0.70.6-1.4
Fecal boli incidents, locomotor time 10.91.02.10.30.71.0-1.00.71.01.31.3-1.30.70.41.0-1.4
Change in fecal boli incidents, locomotor task0.40.41.20.4-1.1-0.30.3-0.1-0.6-0.9-0.70.7-1.10.1-0.40.7
Time >=10cm from walls, locomotor time 11.91.94.6-1.0-0.8-1.41.4-1.8-0.3-1.8-1.71.7-0.80.1-1.42.1
Bouts of movement, locomotor time 11.41.63.10.80.31.5-1.51.11.11.61.5-1.50.30.71.5-1.8
Total resting periods, locomotor time 11.21.42.50.60.41.4-1.40.91.11.51.4-1.40.40.61.4-1.6
Rest time, locomotor task time 10.60.71.10.9-0.51.1-1.10.70.80.70.9-0.9-0.50.90.9-0.8
Distance moved, locomotor task time 10.60.61.3-1.11.0-0.90.9-0.9-0.3-0.4-0.60.61.0-0.7-0.80.6
Vertical activity count, locomotor time 10.50.52.5-0.91.6-0.20.2-0.30.20.50.3-0.31.6-0.6-0.1-0.1
Time >=10cm from walls, locomotor time 21.41.54.41.1-2.00.9-0.9-0.01.6-0.10.4-0.5-2.02.10.80.1
Bouts of movement, locomotor time 21.61.73.10.80.31.6-1.61.11.01.71.5-1.50.30.71.7-1.7
Total resting periods, locomotor time 21.61.73.11.00.01.7-1.71.20.91.61.4-1.40.00.71.8-1.6
Rest time, locomotor task time 20.10.10.3-0.3-0.0-0.40.4-0.4-0.4-0.6-0.50.5-0.0-0.2-0.50.2
Distance moved, locomotor task time 20.10.10.20.10.40.2-0.20.40.00.40.4-0.40.4-0.20.2-0.2
Vertical activity count, locomotor time 21.61.83.30.80.81.5-1.51.60.91.81.8-1.80.80.31.5-1.4
Weight adjusted by age0.91.02.41.1-0.11.1-1.11.5-0.01.21.1-1.0-0.1-0.10.9-1.5
Seeking ratio, delayed vs. immediate footshock1.82.15.0-0.70.0-1.51.5-0.5-2.2-1.7-1.71.70.0-1.7-1.81.4
Locomotion in novel chamber0.40.50.90.20.70.5-0.50.70.40.90.9-0.90.7-0.00.6-0.9
Locomotion in novel chamber post-restriction2.12.55.70.41.31.5-1.51.21.52.22.1-2.11.30.41.4-2.4
Progressive ratio0.50.61.4-0.0-0.7-0.70.7-0.3-0.9-1.2-0.90.9-0.7-0.2-0.61.1
Food seeking constrained by brief footshock1.11.45.5-0.30.4-1.21.20.2-2.4-0.9-1.21.20.4-1.9-1.11.0
Seeking ratio, punishment vs. effort0.30.41.10.40.40.6-0.60.9-0.01.10.7-0.70.4-0.30.6-0.9
Run reversals in cocaine runway, females0.40.40.7-0.50.1-0.60.6-0.4-0.8-0.4-0.80.80.1-0.7-0.50.8
Run reversals in cocaine runway, males1.01.03.7-0.91.9-0.60.60.1-0.90.20.00.01.9-1.5-0.6-0.5
Latency to leave start box in cocaine runway0.10.10.3-0.1-0.5-0.20.2-0.50.4-0.5-0.30.3-0.50.4-0.20.4
Latency to leave start box in cocaine runway, F0.60.71.91.1-1.40.8-0.80.60.50.10.4-0.3-1.41.00.9-0.1
Latency to leave start box in cocaine runway, M1.91.84.0-2.01.9-1.41.4-1.5-0.4-0.8-0.80.81.9-1.3-1.60.4
Cd content in liver3.74.17.6-2.32.6-2.22.2-1.0-2.3-1.1-1.41.42.6-2.8-2.40.7
Co content in liver0.50.52.00.60.70.4-0.41.4-0.70.40.7-0.70.7-0.90.0-0.9
Cu content in liver0.20.30.9-0.40.8-0.60.60.2-0.8-0.2-0.20.20.8-1.0-0.2-0.0
Fe content in liver1.21.43.30.40.71.1-1.10.91.31.51.7-1.70.70.70.9-1.8
K content in liver0.00.00.10.2-0.30.2-0.20.10.3-0.10.1-0.1-0.30.30.2-0.0
Mg content in liver0.40.40.60.7-0.40.7-0.70.70.70.30.8-0.8-0.40.70.6-0.7
Mn content in liver0.40.41.0-0.2-0.1-0.50.5-0.2-1.0-0.8-0.80.8-0.1-0.6-0.70.8
Na content in liver0.20.20.80.3-0.50.4-0.4-0.10.9-0.10.3-0.4-0.50.90.5-0.2
Rb content in liver1.92.33.5-1.40.5-1.91.9-1.4-1.4-1.7-1.81.80.5-1.1-1.81.7
Se content in liver0.81.03.40.6-1.20.9-0.9-0.21.8-0.70.6-0.7-1.21.80.6-0.4
Sr content in liver0.50.42.11.1-0.20.6-0.61.4-0.60.30.5-0.5-0.2-0.40.7-0.5
Zn content in liver3.23.57.22.3-0.72.1-2.12.70.81.92.2-2.2-0.70.92.1-2.1