Ngfr

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000005392 0.31 0.12 5.6e-16 0.29 0.26 0.3 0.29 6.5e-16 4.3e-14 2.6e-16 4.0e-16
2 Brain gene expression ENSRNOG00000005392 0.54 0.1 0.0e+00 0.58 0.6 0.6 0.59 2.0e-65 1.1e-68 6.6e-69 1.7e-67
3 IL gene expression ENSRNOG00000005392 0.24 0.13 4.0e-03 0.12 0.1 0.06 0.06 9.8e-04 2.3e-03 1.3e-02 1.2e-02
4 LHb gene expression ENSRNOG00000005392 0.92 0.07 1.2e-10 0.3 0.31 0.34 0.31 7.3e-08 3.5e-08 6.8e-09 3.3e-08
5 Liver gene expression ENSRNOG00000005392 0.4 0.12 0.0e+00 0.26 0.26 0.26 0.26 1.8e-28 2.9e-29 1.3e-28 5.3e-29
6 NAcc alternative TSS ENSRNOT00000007268 0.05 0.04 5.9e-03 0.01 0.02 0.01 0.01 4.1e-02 1.9e-02 2.6e-02 4.1e-02
7 NAcc alternative TSS ENSRNOT00000107122 0.04 0.04 8.5e-03 0.01 0.01 0.01 0.01 6.4e-02 3.4e-02 3.0e-02 8.4e-02
8 NAcc gene expression ENSRNOG00000005392 0.24 0.11 1.5e-13 0.2 0.18 0.19 0.2 6.9e-15 2.6e-13 6.2e-14 5.1e-15
9 NAcc isoform ratio ENSRNOT00000007268 0.04 0.03 7.5e-03 0.02 0.02 0.01 0.02 2.3e-02 6.3e-03 2.5e-02 1.3e-02
10 NAcc isoform ratio ENSRNOT00000107122 0.05 0.04 3.6e-03 0.02 0.03 0.03 0.02 1.5e-02 2.7e-03 5.7e-03 9.8e-03
11 OFC gene expression ENSRNOG00000005392 0.41 0.15 3.4e-07 0.21 0.26 0.21 0.22 9.9e-06 8.4e-07 1.1e-05 5.7e-06
12 PL alternative TSS ENSRNOT00000007268 0.06 0.04 8.2e-03 0 -0 0 -0 1.6e-01 3.9e-01 3.3e-01 4.1e-01
13 PL alternative TSS ENSRNOT00000107122 0.06 0.05 6.6e-03 0 0 0 0 2.0e-01 3.0e-01 3.3e-01 3.4e-01
14 PL gene expression ENSRNOG00000005392 0.41 0.09 0.0e+00 0.33 0.36 0.34 0.35 3.7e-26 5.3e-28 3.9e-27 2.8e-27

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail4.414.346.2-2.0-1.5-2.3-4.1-2.0-6.14.6-1.4-6.86.6-3.1-1.61.6-1.7
BMI without tail0.30.61.30.70.80.5-0.70.2-0.90.81.1-1.11.10.11.0-1.00.6
Body weight0.72.84.9-1.4-1.0-1.3-2.2-2.0-2.01.5-1.0-2.12.1-2.0-1.41.4-1.6
Epididymis fat weight0.00.10.50.10.3-0.0-0.3-0.20.2-0.70.50.0-0.1-0.3-0.20.20.1
Glucose1.42.13.7-1.9-1.9-1.9-1.1-1.2-0.91.1-1.9-0.90.9-1.3-1.61.6-1.4
Heart weight0.60.81.5-1.1-1.0-1.2-1.2-1.0-0.7-0.1-0.6-0.80.7-1.1-0.90.9-0.8
Left kidney weight0.30.92.1-1.4-1.3-1.3-1.4-1.2-0.10.2-1.1-0.00.0-0.9-0.80.8-1.0
Right kidney weight1.33.85.5-2.3-2.2-2.3-2.4-2.1-1.41.2-2.1-1.31.3-2.0-2.02.0-2.0
Tail length4.513.641.42.42.12.63.31.65.8-4.72.16.4-6.32.82.0-2.01.7
Length with tail1.45.021.2-0.1-0.30.21.1-0.93.9-3.2-0.34.6-4.50.3-0.70.7-0.9
Length without tail1.12.54.6-1.9-1.8-1.6-0.9-1.8-0.60.7-2.1-0.30.4-1.5-2.12.1-2.0
Liver weight, left0.30.51.70.50.50.40.5-0.01.2-1.30.51.2-1.20.10.1-0.10.1
Liver weight, right0.61.02.1-1.0-1.1-1.0-0.8-1.50.6-0.4-1.00.8-0.8-1.0-1.21.2-1.3
Parametrial fat weight0.81.52.41.20.81.10.81.31.5-1.41.51.2-1.41.11.0-1.01.5
Retroperitoneal fat weight0.10.30.9-0.3-0.0-0.3-0.2-0.3-0.90.7-0.2-0.90.9-0.4-0.30.3-0.4
Intraocular pressure0.71.01.41.11.20.90.90.81.0-0.91.21.1-1.10.91.1-1.10.8
Extensor digitorum longus weight1.24.76.7-1.9-1.6-1.9-2.6-2.6-2.31.9-1.8-2.32.3-2.5-2.12.1-2.3
Soleus weight1.44.15.4-1.8-2.0-1.8-1.8-1.8-2.32.3-2.0-2.22.2-1.9-2.12.1-1.9
Tibialis anterior weight0.20.72.01.31.41.30.40.60.3-0.41.30.2-0.20.50.7-0.70.8
Tibia length1.13.04.8-1.8-1.6-1.6-1.1-1.7-1.61.4-2.1-1.41.5-1.8-2.22.2-1.9
Number of licking bursts2.12.53.91.61.11.51.92.01.4-1.01.61.4-1.31.91.6-1.61.8
Food consumed during 24 hour testing period0.91.11.91.00.90.90.60.51.3-1.41.21.4-1.40.81.0-1.00.8
Times rat made contact with spout0.60.71.30.60.20.60.70.71.1-1.00.81.1-1.10.80.7-0.70.7
Mean time between licks in bursts1.62.23.1-1.6-1.6-1.6-1.2-1.5-1.41.0-1.8-1.21.3-1.5-1.71.7-1.6
Mean num. licks in bursts0.91.12.2-1.2-1.0-1.2-1.4-1.5-0.40.0-1.1-0.40.3-1.4-1.11.1-1.3
Std. dev. time between licks in bursts0.91.02.5-0.7-0.6-0.6-0.4-0.7-1.61.5-0.8-1.41.5-0.6-0.90.9-0.9
Water consumed over 24 hours0.00.00.10.1-0.10.1-0.00.20.2-0.20.30.2-0.20.20.2-0.20.2
Indifference point 0 sec0.81.32.0-1.1-1.2-1.0-1.4-1.0-1.20.5-1.1-1.41.3-1.3-1.11.1-0.9
Indifference point AUC0.30.31.1-0.30.0-0.20.1-0.5-0.81.0-0.7-0.50.6-0.3-0.60.6-0.7
Indifference point function ln k0.10.20.30.40.10.30.30.50.6-0.50.60.4-0.50.40.4-0.40.5
Indifference point function log k0.10.20.30.40.10.30.30.50.6-0.50.60.4-0.50.40.4-0.40.5
Delay discounting total patch changes 0 sec1.01.72.5-1.3-1.4-1.2-1.6-1.2-1.30.5-1.3-1.41.4-1.6-1.31.3-1.1
Delay discounting total patch changes 12 sec0.00.00.2-0.20.1-0.00.10.0-0.1-0.5-0.3-0.10.1-0.1-0.10.1-0.0
Delay discounting total patch changes 18 sec1.92.53.8-1.4-1.3-1.3-1.6-1.4-1.91.4-1.5-1.91.9-1.7-1.51.5-1.4
Delay discounting total patch changes 24 sec0.60.81.7-0.8-0.5-0.7-1.0-0.9-0.90.2-0.7-1.11.0-1.3-1.01.0-0.8
Delay discounting total patch changes 6 sec0.91.42.4-1.0-0.7-0.8-1.1-1.2-1.50.9-1.1-1.51.5-1.3-1.21.2-1.2
Delay discounting time to switch 0 sec0.20.30.70.50.40.40.80.80.5-0.30.70.5-0.50.70.5-0.50.7
Delay discounting water rate 0 sec1.42.23.7-1.2-1.1-1.2-1.5-1.3-1.91.9-1.4-1.91.9-1.4-1.11.1-1.3
Delay discounting water rate 12 sec0.81.12.0-0.8-0.7-1.1-1.4-1.4-1.10.5-0.7-1.21.1-1.4-1.01.0-1.2
Delay discounting water rate 18 sec0.10.10.50.10.10.10.00.10.5-0.70.20.3-0.4-0.10.1-0.10.2
Delay discounting water rate 24 sec0.60.81.8-0.8-0.6-0.9-0.9-0.7-1.20.9-0.6-1.31.3-0.9-0.60.6-0.7
Delay discounting water rate 6 sec0.30.51.21.01.10.90.20.5-0.2-0.20.9-0.40.30.30.9-0.90.7
Locomotor activity0.71.22.31.11.11.21.21.5-0.30.70.9-0.40.41.41.4-1.41.3
Locomotor testing distance1.22.04.21.51.51.61.72.0-0.30.51.3-0.50.51.61.6-1.61.8
Locomotor testing rearing1.32.13.71.61.61.81.61.9-0.10.51.5-0.20.21.71.8-1.81.8
Light reinforcement 10.50.91.71.21.21.30.71.20.1-0.41.1-0.10.00.81.1-1.11.2
Light reinforcement 21.01.31.71.31.11.21.11.30.9-1.01.30.8-0.91.21.3-1.31.3
Reaction time number correct1.11.53.0-1.3-1.6-1.5-1.7-1.3-1.00.4-0.8-1.11.0-1.5-1.11.1-1.2
Reaction time mean minus median0.20.31.40.20.50.20.6-0.10.8-0.10.21.2-1.10.50.2-0.20.0
Reaction time mean minus median AUC0.81.03.00.70.90.61.00.41.5-0.90.91.7-1.60.90.6-0.60.5
Reaction time num false alarms0.91.22.01.21.21.30.81.10.8-0.81.00.8-0.81.21.4-1.41.1
Reaction time num false alarms AUC0.81.11.81.11.11.30.91.10.8-0.60.90.8-0.81.21.3-1.31.1
Reaction time trials correct on left1.11.53.0-1.3-1.6-1.5-1.7-1.3-1.00.4-0.8-1.11.0-1.5-1.11.1-1.2
Reaction time trials on left1.01.52.9-1.3-1.6-1.5-1.7-1.2-1.00.4-0.8-1.11.0-1.4-1.11.1-1.1
Reaction time mean0.10.10.6-0.00.10.00.3-0.40.40.5-0.20.8-0.60.2-0.10.1-0.4
Reaction time mean AUC0.10.20.70.10.20.10.5-0.30.40.5-0.00.8-0.70.40.1-0.1-0.3
Median of all reaction times0.10.10.4-0.1-0.1-0.00.2-0.30.10.6-0.20.4-0.30.2-0.10.1-0.4
Reaction time omissions0.60.81.20.90.90.80.50.70.8-0.51.00.9-0.91.01.1-1.10.8
Reaction time false alarm rate1.52.23.31.61.71.81.61.51.1-0.71.21.2-1.11.71.7-1.71.5
Reaction time premature initiation rate0.30.41.20.50.70.70.50.50.7-1.10.40.6-0.60.30.6-0.60.5
Reaction time premature initiations0.10.10.7-0.2-0.2-0.2-0.5-0.30.2-0.8-0.10.0-0.1-0.6-0.10.1-0.2
Std. dev. reaction times0.20.21.2-0.00.10.10.5-0.30.60.4-0.21.1-0.90.4-0.10.1-0.3
Reaction time trials completed1.01.52.9-1.3-1.6-1.5-1.7-1.2-1.00.4-0.8-1.11.0-1.4-1.11.1-1.1
Reaction time trials AUC1.01.42.7-1.2-1.5-1.4-1.6-1.2-0.90.4-0.7-1.11.0-1.4-1.11.1-1.1
Social response proportion1.61.72.11.31.21.21.31.11.4-1.21.41.5-1.41.31.4-1.41.1
Social responses0.91.12.11.21.41.30.71.10.3-0.61.30.1-0.10.81.5-1.51.2
Social time2.43.25.62.12.12.11.62.40.3-0.61.9-0.0-0.01.92.3-2.32.3
Conditioned locomotion0.60.71.0-0.8-1.0-0.9-0.8-0.5-0.80.2-0.6-1.00.9-0.9-0.90.9-0.5
Cocaine response after cond. corrected1.11.34.3-0.7-0.7-0.9-1.0-0.2-1.71.3-0.4-2.12.0-0.8-0.70.7-0.3
Cocaine response after cond. not corrected0.50.51.9-0.4-0.5-0.7-0.70.1-1.00.6-0.0-1.41.3-0.4-0.40.40.1
Cocaine response before conditioning1.31.63.50.90.70.91.00.91.8-1.70.91.9-1.91.11.0-1.00.9
Saline control response0.91.32.51.11.31.21.21.60.6-1.21.10.3-0.41.11.1-1.11.5
Condit. Reinf. active minus inactive responses1.11.32.01.21.31.10.91.21.1-1.41.30.9-1.01.01.1-1.11.4
Condit. Reinf. active-inactive response ratio4.24.47.52.22.11.91.62.51.6-1.82.71.2-1.32.12.3-2.32.7
Condit. Reinf. active responses0.20.20.50.50.70.50.30.40.5-0.70.30.5-0.50.40.5-0.50.5
Condit. Reinf. inactive responses0.81.02.5-1.0-0.7-0.8-0.6-1.2-0.81.0-1.6-0.60.7-1.0-1.01.0-1.3
Condit. Reinf. lever presses0.10.20.9-0.3-0.1-0.2-0.6-0.9-0.10.1-0.50.1-0.1-0.6-0.30.3-0.8
Condit. Reinf. lever reinforcers received0.20.30.60.40.80.60.30.30.6-0.80.30.5-0.60.30.5-0.50.4
Pavlov. Cond. lever latency2.94.04.71.91.81.82.12.22.1-1.92.02.0-2.02.22.0-2.02.1
Pavlov. Cond. magazine entry latency1.01.12.3-1.2-1.1-1.1-1.1-1.50.1-0.3-1.40.3-0.2-1.2-1.21.2-1.4
Pavlov. Cond. change in total contacts1.72.43.2-1.5-1.4-1.3-1.6-1.8-1.61.6-1.7-1.41.4-1.6-1.51.5-1.8
Pavlov. Cond. index score2.12.74.1-1.7-1.5-1.6-1.7-2.0-1.31.0-2.0-1.11.2-1.9-1.81.8-2.0
Pavlov. Cond. latency score1.72.23.5-1.6-1.5-1.4-1.7-1.9-0.90.6-1.8-0.80.8-1.8-1.71.7-1.8
Pavlov. Cond. lever contacts1.92.63.2-1.5-1.4-1.3-1.4-1.6-1.81.7-1.7-1.71.7-1.7-1.61.6-1.7
Pavlov. Cond. magazine entry number2.73.35.42.11.92.01.92.30.8-0.62.30.5-0.62.12.1-2.12.3
Pavlov. Cond. intertrial magazine entries3.14.05.92.21.92.02.12.21.4-0.72.41.4-1.42.42.4-2.42.1
Pavlov. Cond. lever-magazine prob. diff.2.43.14.6-1.8-1.6-1.7-1.8-2.1-1.41.1-2.0-1.31.3-2.0-1.91.9-2.1
Pavlov. Cond. response bias2.02.73.7-1.7-1.5-1.5-1.5-1.8-1.61.4-1.9-1.41.4-1.8-1.81.8-1.9
Conditioned reinforcement - actives0.60.61.10.81.00.80.60.70.4-0.60.90.4-0.40.81.1-1.10.7
Conditioned reinforcement - inactives0.40.41.00.50.10.31.00.90.5-0.50.70.6-0.51.00.5-0.50.8
Conditioned locomotion0.30.40.90.60.70.50.10.90.1-0.20.8-0.10.00.70.9-0.90.9
Intermittent access intake day 1-15 change0.30.31.00.0-0.00.1-0.5-0.1-0.90.9-0.1-1.00.9-0.4-0.00.0-0.0
Intermittent access intake escalation0.20.20.50.1-0.00.2-0.4-0.1-0.60.6-0.1-0.70.7-0.30.0-0.0-0.0
Intermittent access intake escalation 20.30.30.50.60.60.6-0.30.4-0.50.20.4-0.70.6-0.00.5-0.50.5
Intermitt. access day 1 inactive lever presses0.80.91.80.90.61.11.01.30.5-0.11.10.4-0.41.21.2-1.21.2
Intermitt. access day 15 inactive lever presses1.82.02.5-1.4-1.5-1.3-1.3-1.4-1.61.2-1.3-1.51.6-1.4-1.41.4-1.4
Intermitt. access escalation Index0.40.40.60.70.50.70.20.70.5-0.60.80.5-0.50.70.7-0.70.8
Intermittent access day 1 total infusions0.30.31.4-0.0-0.1-0.10.50.11.0-0.50.21.2-1.20.40.2-0.20.0
Intermittent access day 15 total infusions0.20.30.50.50.40.50.60.30.6-0.20.50.7-0.70.40.5-0.50.3
Intermittent access terminal intake (last 3 days)0.10.20.30.40.40.50.50.30.5-0.10.30.5-0.50.30.4-0.40.3
Intermittent access total infusions0.10.10.4-0.1-0.0-0.10.2-0.10.5-0.00.10.6-0.60.10.2-0.2-0.1
Intermittent access day 1 locomotion1.11.23.10.70.40.61.00.71.6-1.30.81.8-1.71.10.7-0.70.7
Intermittent access day 15 total locomotion0.20.20.70.30.20.40.60.20.6-0.80.20.7-0.70.30.3-0.30.1
Intermittent access total locomotion0.40.41.00.40.30.40.80.40.8-0.90.41.0-0.90.60.6-0.60.3
Intermittent access standard deviation0.50.51.2-0.3-0.1-0.4-0.7-0.6-1.01.0-0.4-1.11.1-0.8-0.40.4-0.5
Cocaine induced anxiety0.50.61.30.91.20.90.70.90.2-0.11.10.1-0.10.80.9-0.91.0
Post-drug Anxiety2.12.33.31.71.81.81.81.61.2-1.31.71.2-1.21.51.5-1.51.6
Baseline Anxiety0.20.20.4-0.3-0.5-0.2-0.2-0.50.1-0.6-0.60.0-0.1-0.6-0.70.7-0.5
Lifetime Intake0.10.10.40.00.0-0.00.40.10.6-0.10.10.7-0.60.20.2-0.20.0
Incentive Sensitization - Responses0.80.81.71.11.20.90.90.70.3-0.41.30.4-0.30.91.2-1.20.8
Incentive Sensitization - Breakpoint0.80.81.71.11.31.00.80.70.1-0.31.30.2-0.10.81.2-1.20.9
Progressive ratio test 1 active lever presses1.31.31.90.90.80.81.01.21.4-0.91.21.3-1.41.31.2-1.21.2
Progressive ratio test 1 breakpoint1.21.32.10.80.70.71.01.11.5-1.01.11.4-1.41.21.1-1.11.2
Progressive ratio test 1 inactive lever presses0.30.30.80.40.20.40.50.9-0.40.70.5-0.50.50.80.6-0.60.7
Progressive ratio test 2 active lever presses1.81.92.91.51.51.41.41.31.1-1.01.61.2-1.21.51.7-1.71.3
Progressive ratio test 2 breakpoint1.31.52.61.31.41.21.11.10.8-0.81.60.9-0.91.31.6-1.61.2
Progressive ratio test 2 inactive lever presses0.20.30.60.40.30.30.50.5-0.10.30.70.1-0.00.80.8-0.80.5
Total sessions with >9 infusions0.10.10.6-0.10.1-0.20.40.10.6-0.1-0.10.8-0.70.30.2-0.2-0.1
Short access day 1 total inactive lever presses0.10.10.2-0.10.1-0.10.10.10.4-0.40.20.4-0.40.20.3-0.30.2
Short access day 10 total inactive lever presses0.10.10.30.00.10.2-0.5-0.0-0.3-0.10.1-0.50.4-0.20.2-0.20.1
Short access day 1 total infusions0.20.20.7-0.6-0.3-0.80.3-0.2-0.20.5-0.4-0.10.1-0.1-0.40.4-0.4
Short access day 10 total infusions0.20.20.8-0.6-0.9-0.6-0.5-0.50.40.1-0.40.5-0.5-0.2-0.30.3-0.4
Short access total infusions0.40.51.0-0.9-0.9-1.0-0.4-0.7-0.20.5-0.8-0.10.1-0.6-0.80.8-0.8
Short access day 1 locomotion0.10.10.2-0.4-0.3-0.5-0.3-0.3-0.20.3-0.3-0.10.1-0.3-0.50.5-0.4
Short access day 10 total locomotion0.50.61.30.60.40.50.80.71.0-0.80.61.1-1.10.90.5-0.50.6
Short access total locomotion0.10.10.4-0.4-0.6-0.5-0.1-0.20.20.2-0.40.3-0.3-0.0-0.40.4-0.4
Compulsive drug intake3.73.76.21.92.01.72.31.42.4-2.01.82.5-2.51.71.4-1.41.5
One hour access (0.3 mA shock)0.91.12.01.01.41.01.40.91.0-0.90.91.0-1.00.81.0-1.00.8
One hour access (shock baseline)0.20.20.7-0.1-0.00.1-0.40.1-0.70.6-0.0-0.80.8-0.10.4-0.40.2
Number of responses in last shaping day2.42.43.4-1.5-1.3-1.6-1.2-1.5-1.61.4-1.5-1.61.6-1.6-1.81.8-1.6
Context. condit. distance diff. score0.40.51.6-0.5-0.4-0.5-0.4-0.3-1.01.3-0.5-1.01.1-0.4-0.40.4-0.4
Locomotion velocity, session 10.40.40.70.80.90.70.80.7-0.00.20.80.1-0.00.70.7-0.70.7
Locomotion distance, session 12.22.84.11.71.61.71.91.41.7-1.21.42.0-1.91.91.7-1.71.3
Locomotion velocity, session 20.20.30.6-0.4-0.3-0.3-0.2-0.70.4-0.4-0.70.7-0.6-0.4-0.40.4-0.7
Locomotion distance, session 23.85.47.82.32.32.52.82.22.3-1.91.72.6-2.52.62.3-2.32.0
Locomotion velocity, session 32.02.33.2-1.6-1.4-1.5-1.6-1.8-1.41.2-1.7-1.21.3-1.6-1.51.5-1.8
Locomotion distance, session 30.40.40.80.50.70.60.70.40.8-0.80.30.9-0.90.50.5-0.50.4
Stereotopy head waving bouts, day 33.03.65.2-1.8-1.8-1.6-1.3-1.4-2.32.2-2.1-2.32.3-1.7-2.02.0-1.7
Stereotopy head waving duration, day 32.73.33.9-1.8-1.9-1.7-1.5-1.5-1.91.9-2.0-1.91.9-1.7-1.91.9-1.7
Locomotion velocity, session 70.10.10.3-0.10.00.00.6-0.30.10.5-0.60.5-0.40.2-0.20.2-0.5
Locomotion distance, session 72.73.57.31.51.41.62.51.52.4-1.41.32.7-2.62.11.5-1.51.3
Stereotopy head waving bouts, day 70.50.61.0-0.7-0.3-0.5-0.8-0.8-0.80.5-0.9-0.90.9-1.0-0.90.9-0.8
Stereotopy head waving duration, day 70.70.81.5-0.8-0.5-0.6-1.0-1.1-0.80.3-1.0-0.80.8-1.2-1.11.1-1.0
Locomotion velocity, session 80.91.03.0-0.5-0.2-0.4-0.5-0.7-1.61.7-0.9-1.51.6-0.7-0.60.6-0.8
Locomotion distance, session 80.50.81.51.01.21.11.00.90.5-0.30.80.6-0.61.01.1-1.10.9
Degree of sensitization distance0.10.10.30.1-0.2-0.00.60.20.40.10.10.5-0.50.40.0-0.00.0
Degree of sensitization stereotypy0.30.30.90.61.00.70.30.40.6-0.80.50.4-0.50.30.5-0.50.6
Condit. Reinf. active minus inactive responses0.91.01.31.00.90.90.70.81.0-1.01.11.0-1.01.01.1-1.10.9
Condit. Reinf. active-inactive response ratio0.10.10.20.40.30.30.40.4-0.20.20.5-0.20.20.40.3-0.30.4
Condit. Reinf. active responses1.01.21.61.01.11.00.70.91.2-1.21.01.2-1.21.11.3-1.31.0
Condit. Reinf. inactive responses1.31.52.51.11.21.20.81.11.4-1.61.01.3-1.41.11.3-1.31.3
Incentive salience index mean2.02.43.51.61.61.61.31.51.4-1.41.51.5-1.41.71.9-1.91.6
Condit. Reinf. lever presses3.24.25.42.12.12.32.02.11.9-1.81.81.9-1.82.22.3-2.32.1
Time in familiar zone, hab. session 11.61.52.61.21.01.21.41.61.1-1.21.50.9-1.01.31.0-1.01.5
Time in novel zone, hab. session 14.44.35.3-2.1-1.7-2.1-2.3-2.3-2.12.1-2.2-2.02.0-2.1-1.91.9-2.2
Total zone transitions, hab. session 14.46.37.42.62.62.72.52.12.5-2.22.32.7-2.72.52.6-2.62.2
Total locomotion distance, hab. session 12.84.05.22.02.22.32.21.82.0-1.61.32.2-2.12.02.1-2.11.8
Locomotion velocity, hab. session 13.65.26.62.32.32.62.62.02.3-1.91.62.5-2.42.32.4-2.42.0
Time in familiar zone, hab. session 20.30.31.2-0.2-0.0-0.2-0.7-0.3-0.80.20.1-1.11.0-0.6-0.30.3-0.2
Time in novel zone, hab. session 20.10.10.50.1-0.10.20.70.50.40.2-0.10.5-0.40.60.2-0.20.3
Total zone transitions, hab. session 23.64.76.32.22.42.32.52.02.1-1.91.82.3-2.22.22.1-2.12.0
Total locomotion distance, hab. session 20.71.02.01.01.21.31.41.00.9-0.70.21.1-1.01.00.9-0.90.8
Locomotion velocity, hab. session 20.70.91.60.91.01.21.30.81.0-0.80.11.2-1.10.90.8-0.80.7
Novel to familiar place preference ratio0.70.81.20.90.80.90.60.90.9-0.70.80.8-0.80.91.1-1.11.1
Novelty place preference0.60.61.00.80.70.90.60.90.7-0.40.70.6-0.70.91.0-1.01.0
Time in novel zone, NPP test0.60.61.10.90.70.90.81.00.6-0.20.70.5-0.50.91.0-1.01.0
Total zone transitions, NPP test4.86.910.72.72.73.03.32.72.5-2.12.02.7-2.62.82.6-2.62.5
Total locomotion distance, NPP test1.72.45.61.51.61.82.41.71.3-0.70.71.5-1.41.91.5-1.51.4
Locomotion velocity, NPP test1.41.94.21.31.41.62.01.31.3-0.80.51.6-1.51.61.3-1.31.1
Pavlov. Cond. lever latency3.54.46.0-2.3-2.1-2.4-2.2-2.5-1.41.1-2.1-1.41.4-2.4-2.52.5-2.4
Pavlov. Cond. magazine entry latency1.11.52.41.51.41.51.21.40.4-0.11.30.4-0.31.41.6-1.61.4
Pavlov. Cond. change in total contacts5.65.97.22.62.62.62.42.52.2-1.82.62.1-2.12.62.7-2.72.5
Pavlov. Cond. index score3.24.16.22.42.12.42.12.41.0-0.42.21.0-1.02.42.5-2.52.3
Pavlov. Cond. latency score2.93.75.72.22.02.32.12.31.0-0.32.01.0-0.92.42.4-2.42.2
Pavlov. Cond. lever contacts4.65.47.72.62.32.72.62.71.6-1.12.21.7-1.62.82.7-2.72.6
Pavlov. Cond. magazine entry number1.82.23.4-1.8-1.6-1.8-1.6-1.7-0.90.4-1.6-0.80.8-1.7-1.71.7-1.6
Pavlov. Cond. intertrial magazine entries0.81.03.90.30.40.40.50.41.6-2.00.51.6-1.60.40.3-0.30.5
Pavlov. Cond. lever-magazine prob. diff.3.03.75.82.32.12.21.92.21.0-0.42.10.9-0.92.32.4-2.42.2
Pavlov. Cond. response bias2.63.24.62.12.02.21.82.01.0-0.71.90.9-0.92.02.1-2.12.0
Bone: apparent density0.20.40.7-0.5-0.4-0.5-0.8-0.5-0.60.3-0.4-0.90.8-0.9-0.70.7-0.4
Bone surface0.30.51.2-0.7-0.8-0.7-1.1-0.9-0.50.2-0.6-0.50.5-1.0-0.80.8-0.7
Bone volume0.91.62.3-1.2-1.3-1.2-1.4-1.5-0.90.7-1.2-1.00.9-1.5-1.51.5-1.3
Bone: connectivity density0.10.10.60.00.1-0.1-0.8-0.30.1-0.70.2-0.20.0-0.50.0-0.00.1
Bone: cortical apparent density1.21.64.50.90.51.02.01.01.6-0.30.52.1-1.91.60.7-0.70.6
Bone: cortical area0.60.91.1-1.0-0.7-1.0-0.9-1.1-1.00.8-0.9-0.90.9-1.0-1.01.0-1.0
Bone: cortical porosity0.20.20.5-0.4-0.4-0.3-0.4-0.4-0.70.4-0.4-0.70.7-0.5-0.50.5-0.4
Bone: cortical porosity0.10.10.2-0.3-0.4-0.2-0.3-0.2-0.40.2-0.4-0.40.4-0.3-0.30.3-0.3
Bone: cortical thickness0.81.33.1-1.1-1.0-1.1-0.3-1.0-1.31.8-1.3-1.01.1-0.7-1.21.2-1.3
Bone: cortical thickness0.10.10.50.20.10.20.60.30.20.70.30.3-0.20.60.4-0.40.2
Bone: cortical tissue density1.41.95.21.00.61.12.01.11.8-0.50.62.3-2.11.70.9-0.90.7
Bone: elastic displacement0.10.10.20.30.30.50.40.3-0.20.20.1-0.20.20.20.3-0.30.2
Bone: elastic work0.00.00.10.10.20.20.2-0.0-0.20.3-0.2-0.10.1-0.1-0.00.0-0.1
Bone: endosteal estimation0.00.10.6-0.10.1-0.1-0.8-0.40.2-0.50.10.1-0.1-0.40.1-0.1-0.0
Bone: endosteal perimeter0.10.20.9-0.3-0.1-0.4-0.9-0.5-0.0-0.7-0.1-0.20.1-0.7-0.20.2-0.2
Bone: final force0.00.00.20.10.00.10.50.4-0.00.30.0-0.00.00.30.1-0.10.3
Bone: final moment0.00.10.30.00.00.00.40.4-0.20.5-0.1-0.20.30.3-0.00.00.2
Bone: marrow area0.00.10.40.00.2-0.0-0.7-0.30.3-0.60.20.2-0.2-0.30.2-0.20.0
Bone: maximum diameter0.10.20.8-0.30.0-0.5-0.9-0.5-0.3-0.5-0.0-0.40.3-0.6-0.20.2-0.2
Bone: maximum force0.40.70.9-0.9-0.8-0.9-0.7-0.7-0.80.9-0.8-0.80.8-0.8-0.80.8-0.8
Bone: maximum moment0.50.91.2-1.0-0.8-1.0-0.8-0.8-1.01.1-0.9-1.01.0-0.9-1.01.0-0.9
Bone: minimum diameter0.30.61.0-1.0-0.8-1.0-1.0-1.00.2-0.6-0.80.2-0.2-1.0-0.90.9-0.8
Bone: periosteal estimation0.10.30.7-0.5-0.3-0.6-0.9-0.6-0.40.1-0.4-0.50.4-0.7-0.50.5-0.4
Bone: periosteal perimeter0.50.82.1-0.9-0.7-1.1-1.4-0.9-0.90.2-0.5-1.01.0-1.1-0.70.7-0.7
Bone: post-yield work1.11.42.3-1.3-1.0-1.4-1.5-1.3-1.21.2-1.0-1.21.2-1.2-0.90.9-1.2
Bone: stiffness0.00.10.3-0.4-0.2-0.5-0.0-0.20.00.1-0.20.1-0.1-0.2-0.40.4-0.3
Bone: tissue strength1.61.52.6-1.4-1.3-1.3-0.8-1.2-0.90.6-1.6-0.80.8-1.4-1.61.6-1.4
Bone: trabecular number0.10.21.10.30.40.4-0.00.20.7-1.10.30.4-0.5-0.20.2-0.20.4
Bone: trabecular spacing0.81.01.51.01.11.01.01.2-0.61.01.1-0.50.61.21.1-1.11.0
Bone: trabecular thickness6.68.010.6-3.1-2.8-3.0-2.9-3.2-2.11.7-3.1-2.12.1-3.2-3.23.2-3.1
Bone: trabecular tissue density0.40.61.2-0.8-0.9-0.6-0.2-0.7-0.60.8-1.1-0.30.5-0.5-1.11.1-1.0
Breakpoint value in progressive ratio session1.51.75.61.21.41.20.70.41.8-2.41.21.6-1.70.61.0-1.00.8
Distance traveled before self-admin4.54.86.32.42.52.52.22.11.9-1.72.41.8-1.82.12.4-2.42.2
Distance traveled after self-admin1.01.12.11.31.21.30.41.20.3-0.21.4-0.0-0.01.01.3-1.31.4
Delta time in closed arm before/after self-admin0.70.71.3-0.9-1.0-1.0-1.1-1.1-0.50.5-0.9-0.40.4-0.9-0.80.8-1.0
Delta time in open arm before/after self-admin0.00.00.0-0.1-0.20.00.20.1-0.1-0.20.00.00.00.1-0.10.1-0.0
Diff in mean of infusions in LGA sessions1.61.82.91.51.71.41.00.91.0-1.41.51.1-1.11.31.6-1.61.2
Extinction: sum of active levers before priming0.40.41.9-0.10.2-0.00.2-0.60.8-1.4-0.20.9-0.9-0.4-0.20.2-0.5
Active lever presses in extinction session 60.10.10.20.20.30.2-0.0-0.2-0.40.00.2-0.50.5-0.10.1-0.1-0.1
Delta distance traveled before/after self-admin1.51.62.9-1.1-1.3-1.1-1.5-0.8-1.51.6-1.1-1.71.7-1.0-1.11.1-0.8
Delta ambulatory time before/after self-admin1.51.72.9-1.1-1.3-1.1-1.5-0.9-1.51.6-1.1-1.71.6-1.1-1.11.1-0.9
Time in closed arm before self-admin2.83.27.0-1.8-1.6-1.7-1.4-1.5-2.02.6-1.7-2.02.0-1.5-1.61.6-1.6
Time in closed arm after self-admin4.54.65.7-2.3-2.4-2.3-2.4-2.3-2.02.3-2.2-1.81.9-2.1-1.91.9-2.2
Time in open arm before self-admin1.01.02.61.01.00.90.80.91.2-1.60.91.0-1.10.70.9-0.91.1
Time in open arm after self-admin0.60.71.20.81.01.01.00.90.6-1.10.80.6-0.60.80.6-0.60.8
Sum of active levers in priming session hrs 5-62.72.67.31.21.31.31.40.82.3-2.71.02.4-2.41.01.0-1.00.9
Time to tail flick, vehicle, before self-admin0.70.71.40.81.00.61.20.70.8-0.30.90.9-0.91.00.9-0.90.7
Time to tail flick, vehicle, after self-admin0.80.81.4-0.9-1.2-1.0-0.9-0.9-0.70.5-0.9-0.70.7-1.0-1.11.1-0.9
Time to tail flick, test, before self-admin2.12.12.9-1.5-1.4-1.5-1.4-1.7-1.11.0-1.5-1.11.1-1.6-1.61.6-1.7
Time to tail flick, test, after self-admin1.21.21.7-1.2-1.3-1.2-1.0-1.1-0.81.3-1.1-0.80.8-1.0-1.31.3-1.2
Delta time to tail flick, vehicle, before/after SA1.81.82.5-1.3-1.5-1.3-1.3-1.0-1.51.2-1.3-1.61.5-1.3-1.41.4-1.1
Delta time to tail flick, test, before/after SA0.60.61.00.70.50.81.00.90.8-0.30.60.8-0.80.90.5-0.50.8
Ambulatory time before self-admin3.53.75.22.22.32.21.81.81.5-1.62.21.5-1.51.82.1-2.12.0
Ambulatory time after self-admin0.30.30.60.60.50.7-0.00.60.1-0.10.7-0.20.10.30.7-0.70.8
Total heroin consumption0.70.92.71.01.21.10.60.61.0-1.60.70.8-0.90.40.7-0.70.8
Area under the delay curve0.00.00.1-0.1-0.2-0.2-0.3-0.30.00.1-0.10.0-0.0-0.3-0.20.2-0.2
Delay disc. indifference point, 0s delay0.00.00.20.0-0.3-0.2-0.3-0.1-0.20.40.1-0.10.10.00.0-0.0-0.1
Delay disc. indifference point, 16s delay1.11.21.9-0.9-0.8-1.0-1.3-1.2-1.10.8-1.0-1.21.2-1.4-1.01.0-1.1
Delay disc. indifference point, 2s delay0.20.20.5-0.2-0.4-0.30.1-0.20.6-0.7-0.10.6-0.7-0.2-0.60.6-0.1
Delay disc. indifference point, 24s delay0.40.40.70.80.80.70.20.20.5-0.80.70.6-0.50.50.7-0.70.4
Delay disc. indifference point, 4s delay0.20.30.7-0.4-0.4-0.4-0.3-0.70.7-0.2-0.40.8-0.8-0.4-0.30.3-0.6
Delay disc. indifference point, 8s delay0.00.00.10.1-0.00.10.00.10.30.10.10.3-0.30.10.1-0.10.1
Delay discount exponential model param0.00.00.1-0.00.10.10.30.3-0.20.00.1-0.20.20.20.0-0.00.2
Delay discount hyperbolic model param0.00.00.10.10.20.20.20.3-0.30.10.1-0.30.30.20.2-0.20.2
Fecal boli incidents, locomotor time 12.62.85.0-1.4-1.2-1.5-1.5-1.4-2.22.2-1.3-2.22.2-1.5-1.41.4-1.5
Change in fecal boli incidents, locomotor task1.31.22.50.90.70.70.80.81.5-1.11.21.6-1.61.11.1-1.10.9
Time >=10cm from walls, locomotor time 12.02.03.51.41.41.31.21.80.8-0.61.80.7-0.71.61.9-1.91.9
Bouts of movement, locomotor time 11.51.72.6-1.3-1.2-1.2-0.9-1.4-1.41.6-1.6-1.11.2-1.1-1.21.2-1.6
Total resting periods, locomotor time 12.02.23.4-1.5-1.4-1.5-1.1-1.5-1.61.9-1.7-1.31.4-1.2-1.41.4-1.7
Rest time, locomotor task time 10.30.30.5-0.6-0.7-0.7-0.3-0.4-0.50.5-0.6-0.40.4-0.4-0.60.6-0.5
Distance moved, locomotor task time 13.23.54.11.92.01.91.81.62.0-2.01.91.9-2.01.61.8-1.81.8
Vertical activity count, locomotor time 10.90.92.41.21.51.21.10.80.5-0.51.00.6-0.50.81.1-1.10.8
Time >=10cm from walls, locomotor time 21.21.32.01.10.80.91.21.41.0-0.71.41.0-1.01.41.3-1.31.3
Bouts of movement, locomotor time 20.10.10.30.30.30.20.10.20.1-0.10.30.1-0.10.20.5-0.50.3
Total resting periods, locomotor time 20.10.20.40.40.50.40.30.40.1-0.30.40.1-0.10.30.6-0.60.4
Rest time, locomotor task time 20.40.42.70.30.20.20.30.30.9-1.60.40.8-0.90.20.1-0.10.4
Distance moved, locomotor task time 20.10.10.2-0.2-0.5-0.2-0.1-0.40.00.4-0.40.2-0.1-0.1-0.30.3-0.5
Vertical activity count, locomotor time 20.10.11.00.10.00.10.1-0.2-0.41.0-0.1-0.10.30.10.0-0.0-0.3
Weight adjusted by age0.10.10.5-0.1-0.2-0.1-0.7-0.30.10.40.10.1-0.1-0.10.2-0.2-0.1
Seeking ratio, delayed vs. immediate footshock1.01.12.1-1.1-1.2-1.3-1.5-0.9-1.10.5-1.0-1.11.1-1.1-0.90.9-0.9
Locomotion in novel chamber1.01.21.71.11.11.10.71.01.3-1.21.21.0-1.10.81.2-1.21.3
Locomotion in novel chamber post-restriction0.10.10.4-0.4-0.3-0.3-0.20.2-0.3-0.7-0.2-0.40.4-0.3-0.20.20.2
Progressive ratio0.50.61.40.80.90.90.51.10.5-0.70.70.2-0.30.50.7-0.71.2
Food seeking constrained by brief footshock0.30.30.80.60.60.80.90.90.2-0.70.40.0-0.10.50.1-0.10.7
Seeking ratio, punishment vs. effort0.10.10.2-0.1-0.3-0.10.5-0.30.3-0.1-0.20.5-0.40.2-0.30.3-0.4
Run reversals in cocaine runway, females0.20.20.7-0.4-0.6-0.3-0.7-0.8-0.30.1-0.6-0.10.1-0.5-0.40.4-0.7
Run reversals in cocaine runway, males0.10.10.40.20.40.20.30.5-0.4-0.20.1-0.60.6-0.10.1-0.10.4
Latency to leave start box in cocaine runway5.45.98.4-2.5-2.6-2.5-2.9-2.6-1.82.1-2.3-2.01.9-2.9-2.52.5-2.4
Latency to leave start box in cocaine runway, F7.88.613.7-3.1-3.3-3.1-3.7-2.9-2.22.5-2.9-2.52.3-3.3-3.03.0-2.7
Latency to leave start box in cocaine runway, M0.10.10.20.10.40.1-0.1-0.5-0.20.40.1-0.20.2-0.30.0-0.0-0.3
Cd content in liver3.43.75.82.02.22.22.02.41.6-2.21.81.2-1.41.71.8-1.82.4
Co content in liver0.40.40.80.70.70.90.80.9-0.10.40.2-0.10.10.70.8-0.80.7
Cu content in liver6.78.111.32.82.83.03.02.43.1-2.52.53.4-3.32.92.8-2.82.4
Fe content in liver1.61.93.61.21.11.31.51.11.8-1.90.91.8-1.81.10.9-0.91.0
K content in liver0.40.41.1-0.6-0.8-0.50.1-0.70.40.1-1.00.8-0.6-0.2-0.80.8-0.8
Mg content in liver0.70.73.10.2-0.20.41.20.31.4-0.7-0.21.8-1.60.70.1-0.10.0
Mn content in liver1.61.83.11.31.31.31.10.91.6-1.61.21.8-1.71.21.3-1.31.1
Na content in liver0.20.20.5-0.4-0.4-0.20.1-0.40.5-0.0-0.60.7-0.6-0.1-0.30.3-0.4
Rb content in liver0.50.61.61.10.81.21.30.90.5-0.60.70.5-0.50.70.1-0.10.7
Se content in liver0.10.10.50.10.10.20.40.50.4-0.70.20.2-0.30.1-0.10.10.5
Sr content in liver0.40.40.6-0.7-0.7-0.6-0.5-0.80.5-0.5-0.60.6-0.6-0.5-0.50.5-0.7
Zn content in liver0.91.01.70.80.51.01.21.31.0-1.00.50.9-1.01.11.1-1.11.2