Hub : Genes

Pgap2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression ENSRNOG00000020371 0.09 0.06 1.3e-03 0.04 0.06 0.03 0.04 3.5e-03 5.8e-04 7.1e-03 5.7e-03
2 Brain gene expression ENSRNOG00000020371 0.05 0.04 3.3e-04 0.04 0.02 0.02 0.02 3.4e-04 3.1e-03 8.2e-03 3.6e-03
3 Brain mRNA stability ENSRNOG00000020371 0.04 0.03 2.5e-04 0.04 0.04 0.03 0.03 1.0e-04 2.5e-04 6.1e-04 4.3e-04
4 Liver alternative TSS ENSRNOT00000055235 0.05 0.04 3.2e-04 0.03 0.02 0.02 0.02 6.7e-04 1.8e-03 2.5e-03 3.1e-03
5 Liver alternative TSS ENSRNOT00000076894 0.05 0.04 2.8e-04 0.03 0.02 0.02 0.02 6.3e-04 2.0e-03 1.9e-03 3.3e-03
6 Liver gene expression ENSRNOG00000020371 0.47 0.13 0.0e+00 0.29 0.36 0.36 0.36 1.6e-32 1.6e-41 3.2e-41 4.3e-42
7 Liver isoform ratio ENSRNOT00000055235 0.04 0.03 1.1e-03 0.02 0.02 0.02 0.02 9.4e-04 2.9e-03 2.3e-03 2.9e-03
8 Liver isoform ratio ENSRNOT00000076894 0.04 0.03 2.0e-03 0.02 0.02 0.02 0.02 1.1e-03 5.2e-03 3.6e-03 5.2e-03
9 Liver intron excision ratio chr1:156591841:156603076 0.06 0.05 8.5e-05 0.03 0.02 0.02 0.02 4.0e-04 9.2e-04 4.4e-03 1.7e-03
10 Liver intron excision ratio chr1:156611446:156615573 0.04 0.03 5.7e-04 0.02 0.01 0.01 0.01 2.1e-03 1.2e-02 1.5e-02 6.7e-03
11 Liver mRNA stability ENSRNOG00000020371 0.04 0.03 1.6e-03 0.02 0.02 0.01 0.01 4.6e-03 4.5e-03 7.1e-03 1.2e-02
12 PL gene expression ENSRNOG00000020371 0.05 0.04 7.5e-03 0.03 0.01 0.01 0.02 3.2e-03 4.9e-02 6.7e-02 9.5e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
BMI with tail0.41.45.3-1.6-0.9-2.3-0.90.90.0-0.90.9-1.7-0.8-0.5-0.9
BMI without tail0.71.52.21.01.30.41.3-1.31.31.3-1.3-1.31.51.31.1
Body weight0.31.31.81.31.31.21.3-1.30.81.3-1.3-0.11.30.91.1
Epididymis fat weight0.20.40.7-0.5-0.70.1-0.70.7-0.6-0.70.70.7-0.7-0.8-0.8
Glucose0.20.31.3-0.6-0.2-1.2-0.20.20.3-0.20.2-1.0-0.20.1-0.2
Heart weight1.62.33.11.41.70.71.7-1.71.41.7-1.7-0.81.81.51.7
Left kidney weight1.13.23.91.82.00.92.0-2.01.72.0-2.0-1.11.91.82.0
Right kidney weight0.82.22.81.61.71.11.7-1.71.21.7-1.7-0.41.71.31.6
Tail length5.717.226.15.14.44.94.4-4.42.84.4-4.40.44.53.54.1
Length with tail2.69.616.34.03.34.03.3-3.31.73.3-3.31.13.32.33.0
Length without tail0.10.20.6-0.3-0.4-0.1-0.40.4-0.6-0.40.40.8-0.4-0.6-0.4
Liver weight, left1.82.98.3-0.5-1.51.3-1.51.5-2.2-1.51.52.9-1.7-1.8-1.5
Liver weight, right1.22.010.30.3-0.72.2-0.70.7-1.9-0.70.73.2-0.5-1.5-0.9
Parametrial fat weight0.61.22.7-1.5-1.1-1.7-1.11.1-0.6-1.11.1-0.2-0.8-1.0-1.3
Retroperitoneal fat weight0.82.64.6-1.1-1.50.4-1.51.5-2.0-1.51.52.1-1.5-2.0-1.8
Intraocular pressure0.10.10.4-0.4-0.2-0.6-0.20.20.1-0.20.2-0.5-0.40.1-0.0
Extensor digitorum longus weight0.10.40.5-0.6-0.7-0.4-0.70.7-0.6-0.70.70.3-0.7-0.6-0.6
Soleus weight0.10.41.80.1-0.31.0-0.30.3-0.8-0.30.31.3-0.2-0.6-0.3
Tibialis anterior weight0.10.20.90.70.40.90.4-0.40.00.4-0.40.50.40.20.4
Tibia length0.41.21.51.21.20.81.2-1.21.11.2-1.2-0.51.11.21.2
Number of licking bursts3.94.66.0-2.1-2.2-0.9-2.22.2-2.2-2.22.21.9-2.3-2.5-2.4
Food consumed during 24 hour testing period2.53.04.21.41.80.21.8-1.82.11.8-1.8-1.71.82.01.8
Times rat made contact with spout0.20.21.0-0.2-0.40.4-0.40.4-0.6-0.40.41.0-0.3-0.6-0.5
Mean time between licks in bursts6.69.214.33.83.23.53.2-3.22.23.2-3.20.03.02.83.1
Mean num. licks in bursts3.23.94.82.02.11.02.1-2.12.02.1-2.1-1.52.12.22.1
Std. dev. time between licks in bursts1.51.74.31.81.42.11.4-1.40.71.4-1.40.61.10.91.2
Water consumed over 24 hours0.50.60.9-0.8-0.8-0.4-0.80.8-0.9-0.80.80.7-0.7-0.9-0.9
Indifference point 0 sec2.54.15.21.72.20.72.2-2.22.32.2-2.2-1.72.32.22.2
Indifference point AUC0.50.61.00.80.80.70.8-0.80.50.8-0.80.11.00.60.9
Indifference point function ln k0.10.20.40.10.4-0.30.4-0.40.50.4-0.4-0.60.40.40.1
Indifference point function log k0.10.20.40.10.4-0.30.4-0.40.50.4-0.4-0.60.40.40.1
Delay discounting total patch changes 0 sec2.13.44.51.52.00.42.0-2.02.12.0-2.0-1.72.12.02.0
Delay discounting total patch changes 12 sec1.11.52.11.31.31.01.3-1.31.11.3-1.3-0.41.41.21.5
Delay discounting total patch changes 18 sec0.91.11.71.01.10.51.1-1.11.21.1-1.1-0.71.31.21.3
Delay discounting total patch changes 24 sec1.62.12.91.61.61.21.6-1.61.21.6-1.6-0.41.61.41.7
Delay discounting total patch changes 6 sec1.21.93.01.21.50.51.5-1.51.31.5-1.5-1.11.51.41.7
Delay discounting time to switch 0 sec4.46.78.6-2.4-2.8-0.8-2.82.8-2.7-2.82.81.9-2.9-2.7-2.7
Delay discounting water rate 0 sec3.55.57.72.12.60.62.6-2.62.52.6-2.6-1.72.82.42.4
Delay discounting water rate 12 sec2.13.17.60.71.7-1.21.7-1.72.31.7-1.7-2.81.61.91.5
Delay discounting water rate 18 sec3.14.15.71.62.10.12.1-2.12.42.1-2.1-2.22.02.32.0
Delay discounting water rate 24 sec0.40.52.1-0.00.5-0.90.5-0.51.00.5-0.5-1.50.40.70.4
Delay discounting water rate 6 sec0.81.12.90.31.0-1.01.0-1.01.41.0-1.0-1.71.01.20.9
Locomotor activity0.50.81.20.60.9-0.20.9-0.91.10.9-0.9-1.00.81.00.8
Locomotor testing distance1.72.94.21.41.80.11.8-1.82.11.8-1.8-1.61.71.91.7
Locomotor testing rearing0.71.01.41.21.10.71.1-1.11.11.1-1.1-0.51.01.10.9
Light reinforcement 12.44.36.5-2.5-2.2-2.0-2.22.2-1.7-2.22.20.2-2.1-2.0-2.2
Light reinforcement 21.21.67.7-1.7-0.8-2.8-0.80.80.4-0.80.8-1.9-0.7-0.2-0.7
Reaction time number correct0.00.10.4-0.3-0.2-0.6-0.20.20.1-0.20.2-0.4-0.10.1-0.1
Reaction time mean minus median0.30.40.70.80.70.70.7-0.70.60.7-0.7-0.40.60.60.7
Reaction time mean minus median AUC0.20.30.40.60.50.50.5-0.50.60.5-0.5-0.50.40.60.6
Reaction time num false alarms2.73.75.8-1.2-2.00.3-2.02.0-2.4-2.02.02.1-2.2-2.1-1.7
Reaction time num false alarms AUC2.63.75.3-1.4-2.10.0-2.12.1-2.2-2.12.11.9-2.3-2.0-1.8
Reaction time trials correct on left0.00.10.4-0.3-0.2-0.6-0.20.20.1-0.20.2-0.4-0.10.1-0.1
Reaction time trials on left0.10.10.5-0.4-0.2-0.7-0.20.20.0-0.20.2-0.4-0.20.0-0.2
Reaction time mean1.72.33.8-0.9-1.50.6-1.51.5-1.9-1.51.51.9-1.6-1.8-1.6
Reaction time mean AUC2.12.84.3-1.1-1.70.5-1.71.7-2.1-1.71.72.0-1.8-1.9-1.7
Median of all reaction times2.83.85.6-1.4-2.00.3-2.02.0-2.4-2.02.02.2-2.0-2.3-2.1
Reaction time omissions1.11.52.7-1.2-1.4-0.7-1.41.4-1.0-1.41.40.4-1.7-1.1-1.3
Reaction time false alarm rate2.33.34.6-1.3-1.90.0-1.91.9-2.1-1.91.91.8-2.1-2.0-1.8
Reaction time premature initiation rate1.82.43.51.81.61.51.6-1.61.31.6-1.6-0.31.91.51.6
Reaction time premature initiations0.91.31.91.21.20.81.2-1.21.11.2-1.2-0.61.41.21.2
Std. dev. reaction times0.30.41.90.5-0.11.4-0.10.1-0.6-0.10.11.2-0.3-0.4-0.1
Reaction time trials completed0.10.10.5-0.4-0.2-0.7-0.20.20.0-0.20.2-0.4-0.20.0-0.2
Reaction time trials AUC0.00.00.2-0.2-0.1-0.5-0.10.10.1-0.10.1-0.3-0.10.1-0.1
Social response proportion0.10.10.5-0.1-0.20.2-0.20.2-0.7-0.20.20.5-0.3-0.5-0.2
Social responses0.20.31.10.0-0.30.8-0.30.3-0.8-0.30.31.1-0.3-0.6-0.4
Social time2.93.74.6-1.9-2.1-1.2-2.12.1-1.8-2.12.10.8-2.1-1.9-2.1
Conditioned locomotion0.40.51.4-0.2-0.60.5-0.60.6-0.9-0.60.61.2-0.7-0.8-0.6
Cocaine response after cond. corrected1.51.62.1-1.1-1.4-0.4-1.41.4-1.4-1.41.41.0-1.4-1.4-1.2
Cocaine response after cond. not corrected0.91.01.5-1.1-1.1-1.0-1.11.1-0.8-1.11.10.0-1.2-0.8-0.9
Cocaine response before conditioning1.21.44.50.51.0-0.91.0-1.01.71.0-1.0-2.10.81.41.0
Saline control response2.63.55.62.41.92.21.9-1.91.31.9-1.90.01.91.81.9
Condit. Reinf. active minus inactive responses8.210.111.83.43.42.33.4-3.43.13.4-3.4-1.53.33.43.3
Condit. Reinf. active-inactive response ratio1.61.72.21.21.40.51.4-1.41.51.4-1.4-1.01.21.51.3
Condit. Reinf. active responses10.314.317.14.14.12.94.1-4.13.64.1-4.1-1.64.03.93.9
Condit. Reinf. inactive responses5.67.09.03.02.92.42.9-2.92.32.9-2.9-0.82.92.62.7
Condit. Reinf. lever presses15.621.525.84.55.02.25.0-5.04.95.0-5.0-3.34.95.14.9
Condit. Reinf. lever reinforcers received11.015.418.14.24.32.94.3-4.33.74.3-4.3-1.84.24.14.1
Pavlov. Cond. lever latency17.524.030.1-4.5-5.2-1.6-5.25.2-5.4-5.25.24.1-5.1-5.5-5.2
Pavlov. Cond. magazine entry latency4.45.011.01.22.1-1.12.1-2.13.02.1-2.1-3.32.12.62.1
Pavlov. Cond. change in total contacts15.421.527.44.24.91.34.9-4.95.24.9-4.9-4.14.85.24.9
Pavlov. Cond. index score13.217.222.83.64.40.84.4-4.44.84.4-4.4-4.04.34.74.3
Pavlov. Cond. latency score11.814.920.73.24.00.44.0-4.04.54.0-4.0-4.04.04.44.0
Pavlov. Cond. lever contacts18.225.431.24.75.41.95.4-5.45.55.4-5.4-4.05.35.65.3
Pavlov. Cond. magazine entry number7.49.114.0-2.2-3.10.3-3.13.1-3.7-3.13.13.7-3.0-3.5-3.0
Pavlov. Cond. intertrial magazine entries0.50.73.31.10.51.80.5-0.5-0.20.5-0.51.20.40.20.5
Pavlov. Cond. lever-magazine prob. diff.13.016.822.03.64.30.84.3-4.34.74.3-4.3-3.94.34.64.3
Pavlov. Cond. response bias18.725.832.44.65.41.45.4-5.45.75.4-5.4-4.55.35.75.3
Conditioned reinforcement - actives0.10.10.40.10.0-0.00.0-0.00.30.0-0.0-0.70.10.40.3
Conditioned reinforcement - inactives0.40.41.4-0.1-0.50.9-0.50.5-0.9-0.50.51.2-0.4-0.7-0.4
Conditioned locomotion0.70.82.90.40.6-0.50.6-0.61.20.6-0.6-1.70.61.21.0
Intermittent access intake day 1-15 change1.01.03.60.10.8-1.20.8-0.81.20.8-0.8-1.90.81.00.8
Intermittent access intake escalation0.80.83.3-0.00.6-1.30.6-0.61.00.6-0.6-1.80.70.80.6
Intermittent access intake escalation 20.10.10.7-0.5-0.0-0.9-0.00.00.1-0.00.0-0.6-0.1-0.1-0.3
Intermitt. access day 1 inactive lever presses0.70.72.8-0.5-0.50.5-0.50.5-1.2-0.50.51.7-0.6-1.3-1.0
Intermitt. access day 15 inactive lever presses0.91.01.50.91.20.31.2-1.20.71.2-1.2-0.41.20.71.0
Intermitt. access escalation Index0.10.10.40.40.00.60.0-0.0-0.30.0-0.00.60.2-0.00.1
Intermittent access day 1 total infusions0.70.81.11.01.10.81.1-1.10.71.1-1.1-0.00.90.90.8
Intermittent access day 15 total infusions0.50.60.70.60.8-0.00.8-0.80.80.8-0.8-0.80.80.90.8
Intermittent access terminal intake (last 3 days)0.50.50.70.60.90.00.9-0.90.80.9-0.9-0.60.70.80.6
Intermittent access total infusions0.20.20.30.50.50.10.5-0.50.50.5-0.5-0.20.50.50.3
Intermittent access day 1 locomotion0.10.10.30.1-0.20.5-0.20.2-0.4-0.20.20.5-0.2-0.2-0.0
Intermittent access day 15 total locomotion0.30.41.50.30.4-0.60.4-0.40.60.4-0.4-1.20.40.80.8
Intermittent access total locomotion0.20.20.50.50.40.10.4-0.40.50.4-0.4-0.60.40.70.7
Intermittent access standard deviation0.10.10.8-0.6-0.2-0.9-0.20.20.0-0.20.2-0.4-0.1-0.2-0.4
Cocaine induced anxiety3.03.45.3-1.3-1.90.4-1.91.9-2.3-1.91.92.1-1.8-2.1-1.9
Post-drug Anxiety0.60.63.20.5-0.21.4-0.20.2-1.1-0.20.21.80.0-0.6-0.2
Baseline Anxiety2.83.03.82.02.01.02.0-2.01.42.0-2.0-0.31.91.71.8
Lifetime Intake0.50.60.80.80.80.10.8-0.80.90.8-0.8-0.60.80.90.7
Incentive Sensitization - Responses0.50.50.90.80.70.90.7-0.70.60.7-0.70.10.70.60.6
Incentive Sensitization - Breakpoint0.30.30.40.60.60.60.6-0.60.60.6-0.6-0.10.50.60.4
Progressive ratio test 1 active lever presses0.00.00.00.10.10.00.1-0.1-0.00.1-0.1-0.10.10.10.1
Progressive ratio test 1 breakpoint0.00.00.00.10.20.10.2-0.20.00.2-0.20.00.10.10.0
Progressive ratio test 1 inactive lever presses0.00.00.00.10.0-0.00.0-0.0-0.10.0-0.00.0-0.00.00.1
Progressive ratio test 2 active lever presses0.10.10.50.40.10.70.1-0.1-0.00.1-0.10.20.10.20.2
Progressive ratio test 2 breakpoint0.10.10.70.60.20.80.2-0.20.10.2-0.20.20.30.30.3
Progressive ratio test 2 inactive lever presses0.00.00.00.20.10.10.1-0.10.10.1-0.1-0.20.20.20.2
Total sessions with >9 infusions1.61.84.80.81.1-0.71.1-1.11.81.1-1.1-2.21.01.81.3
Short access day 1 total inactive lever presses0.30.31.3-0.1-0.20.8-0.20.2-0.8-0.20.21.1-0.2-0.8-0.5
Short access day 10 total inactive lever presses0.50.61.0-0.8-0.7-0.3-0.70.7-0.8-0.70.70.7-0.9-1.0-0.9
Short access day 1 total infusions1.21.31.61.11.20.71.2-1.21.21.2-1.2-0.71.11.31.2
Short access day 10 total infusions0.91.01.31.01.10.21.1-1.11.01.1-1.1-0.61.01.11.0
Short access total infusions1.11.21.51.11.20.31.2-1.21.11.2-1.2-0.81.21.21.1
Short access day 1 locomotion0.60.62.2-0.10.7-1.10.7-0.71.00.7-0.7-1.50.40.70.4
Short access day 10 total locomotion0.10.10.4-0.5-0.3-0.6-0.30.30.1-0.30.3-0.4-0.3-0.1-0.3
Short access total locomotion0.10.10.3-0.3-0.3-0.6-0.30.3-0.0-0.30.3-0.4-0.4-0.0-0.2
Compulsive drug intake0.20.20.4-0.6-0.5-0.1-0.50.5-0.4-0.50.5-0.1-0.4-0.5-0.4
One hour access (0.3 mA shock)0.40.51.30.30.5-0.30.5-0.51.10.5-0.5-1.20.70.90.7
One hour access (shock baseline)0.60.61.10.80.80.10.8-0.81.10.8-0.8-0.50.90.90.7
Number of responses in last shaping day0.30.31.30.3-0.41.1-0.40.4-0.7-0.40.41.1-0.2-0.3-0.2
Context. condit. distance diff. score3.23.95.91.62.0-0.02.0-2.02.42.0-2.0-2.11.82.32.1
Locomotion velocity, session 10.91.02.9-1.4-1.0-1.7-1.01.0-0.3-1.01.0-0.7-0.8-0.6-0.9
Locomotion distance, session 10.50.63.0-0.00.4-1.00.4-0.41.10.4-0.4-1.70.30.80.5
Locomotion velocity, session 20.30.31.3-0.6-0.3-1.1-0.30.30.5-0.30.3-1.1-0.30.2-0.1
Locomotion distance, session 20.30.52.5-0.30.3-1.20.3-0.31.00.3-0.3-1.60.30.60.3
Locomotion velocity, session 30.50.50.90.70.70.30.7-0.71.00.7-0.7-0.80.50.90.8
Locomotion distance, session 30.80.81.50.60.9-0.10.9-0.91.20.9-0.9-1.20.81.10.9
Stereotopy head waving bouts, day 30.10.20.90.40.01.00.0-0.0-0.40.0-0.00.7-0.2-0.10.1
Stereotopy head waving duration, day 30.20.20.40.30.4-0.00.4-0.40.50.4-0.4-0.60.20.60.5
Locomotion velocity, session 70.30.31.2-0.8-0.5-1.1-0.50.50.1-0.50.5-0.6-0.4-0.2-0.4
Locomotion distance, session 70.10.10.3-0.4-0.4-0.1-0.40.4-0.4-0.40.40.4-0.1-0.5-0.5
Stereotopy head waving bouts, day 72.83.24.51.71.80.71.8-1.82.01.8-1.8-1.61.72.12.0
Stereotopy head waving duration, day 72.83.45.01.71.90.51.9-1.92.11.9-1.9-1.91.72.22.0
Locomotion velocity, session 81.11.42.11.11.20.31.2-1.21.41.2-1.2-1.01.01.41.4
Locomotion distance, session 82.43.56.11.31.9-0.41.9-1.92.51.9-1.9-2.51.62.21.9
Degree of sensitization distance0.30.31.60.2-0.20.9-0.20.2-0.7-0.20.21.3-0.1-0.6-0.3
Degree of sensitization stereotypy5.56.08.42.22.50.82.5-2.52.82.5-2.5-2.32.42.92.7
Condit. Reinf. active minus inactive responses1.21.32.91.51.21.71.2-1.20.41.2-1.20.41.00.81.1
Condit. Reinf. active-inactive response ratio1.92.15.32.01.42.31.4-1.40.51.4-1.40.81.31.01.3
Condit. Reinf. active responses0.30.41.80.80.41.40.4-0.4-0.20.4-0.40.90.30.10.4
Condit. Reinf. inactive responses0.40.50.6-0.7-0.8-0.4-0.80.8-0.6-0.80.80.4-0.8-0.7-0.7
Incentive salience index mean0.50.62.11.10.71.50.7-0.70.00.7-0.70.70.50.40.7
Condit. Reinf. lever presses0.00.00.10.0-0.10.3-0.10.1-0.3-0.10.10.3-0.1-0.2-0.1
Time in familiar zone, hab. session 10.20.20.40.40.50.10.5-0.50.60.5-0.5-0.40.40.50.5
Time in novel zone, hab. session 10.20.20.8-0.1-0.40.5-0.40.4-0.7-0.40.40.9-0.2-0.6-0.5
Total zone transitions, hab. session 10.10.20.8-0.00.2-0.60.2-0.20.60.2-0.2-0.90.30.50.3
Total locomotion distance, hab. session 10.20.31.50.50.11.20.1-0.1-0.50.1-0.11.1-0.1-0.30.1
Locomotion velocity, hab. session 10.10.20.90.3-0.10.9-0.10.1-0.5-0.10.10.9-0.2-0.3-0.1
Time in familiar zone, hab. session 23.53.74.62.12.11.82.1-2.11.62.1-2.1-0.32.11.82.0
Time in novel zone, hab. session 22.02.04.4-1.8-1.4-2.1-1.41.4-0.8-1.41.4-0.6-1.4-1.1-1.4
Total zone transitions, hab. session 22.73.54.71.51.9-0.01.9-1.92.21.9-1.9-2.11.82.12.2
Total locomotion distance, hab. session 20.91.21.91.41.21.31.2-1.20.71.2-1.20.11.10.91.3
Locomotion velocity, hab. session 20.81.11.81.31.11.31.1-1.10.61.1-1.10.31.10.81.1
Novel to familiar place preference ratio0.80.83.51.20.71.90.7-0.7-0.20.7-0.71.40.50.10.4
Novelty place preference0.70.83.11.20.71.80.7-0.7-0.10.7-0.71.30.60.20.4
Time in novel zone, NPP test1.01.03.61.40.91.90.9-0.90.10.9-0.91.20.70.40.6
Total zone transitions, NPP test0.40.52.6-0.6-0.1-1.6-0.10.10.7-0.10.1-1.6-0.10.40.1
Total locomotion distance, NPP test0.10.10.2-0.5-0.3-0.5-0.30.3-0.2-0.30.3-0.1-0.4-0.4-0.3
Locomotion velocity, NPP test0.30.40.7-0.8-0.7-0.8-0.70.7-0.5-0.70.7-0.1-0.6-0.7-0.7
Pavlov. Cond. lever latency0.60.81.2-1.1-0.9-1.1-0.90.9-0.7-0.90.9-0.1-0.8-0.9-0.9
Pavlov. Cond. magazine entry latency3.03.84.72.02.10.92.1-2.12.12.1-2.1-1.42.12.22.1
Pavlov. Cond. change in total contacts1.21.32.71.51.11.61.1-1.10.81.1-1.10.11.01.11.2
Pavlov. Cond. index score1.92.43.11.71.61.11.6-1.61.61.6-1.6-0.91.51.81.7
Pavlov. Cond. latency score1.72.12.81.71.51.21.5-1.51.41.5-1.5-0.61.41.61.6
Pavlov. Cond. lever contacts0.50.60.91.00.80.80.8-0.80.70.8-0.8-0.10.70.90.9
Pavlov. Cond. magazine entry number2.63.34.1-1.8-1.9-0.8-1.91.9-1.9-1.91.91.3-1.9-2.0-1.9
Pavlov. Cond. intertrial magazine entries1.01.21.8-0.9-1.2-0.1-1.21.2-1.3-1.21.21.0-1.3-1.2-1.0
Pavlov. Cond. lever-magazine prob. diff.1.51.92.51.51.51.01.5-1.51.41.5-1.5-0.81.41.61.5
Pavlov. Cond. response bias0.91.11.31.11.10.61.1-1.11.11.1-1.1-0.61.01.11.1
Bone: apparent density0.20.30.4-0.6-0.5-0.2-0.50.5-0.4-0.50.50.3-0.5-0.5-0.6
Bone surface0.51.01.41.11.01.21.0-1.00.71.0-1.00.11.20.90.9
Bone volume0.30.51.10.90.81.10.8-0.80.50.8-0.80.20.90.60.6
Bone: connectivity density0.30.52.0-1.1-0.6-1.4-0.60.60.0-0.60.6-0.7-0.5-0.3-0.7
Bone: cortical apparent density1.01.43.2-0.7-1.10.3-1.11.1-1.5-1.11.11.8-1.0-1.4-1.2
Bone: cortical area0.30.40.70.80.70.80.7-0.70.40.7-0.70.20.70.50.6
Bone: cortical porosity0.10.10.30.50.30.50.3-0.30.10.3-0.30.20.10.30.3
Bone: cortical porosity0.10.10.30.50.30.60.3-0.30.10.3-0.30.30.30.30.4
Bone: cortical thickness0.30.40.9-0.8-0.7-0.9-0.70.7-0.3-0.70.7-0.1-0.6-0.5-0.7
Bone: cortical thickness0.00.00.00.10.1-0.00.1-0.10.10.1-0.10.00.10.10.1
Bone: cortical tissue density1.01.43.1-0.8-1.10.3-1.11.1-1.5-1.11.11.8-1.1-1.4-1.2
Bone: elastic displacement2.02.33.4-1.8-1.6-1.8-1.61.6-1.2-1.61.60.2-1.6-1.4-1.6
Bone: elastic work3.03.97.4-2.6-2.0-2.7-2.02.0-1.3-2.02.0-0.2-1.8-1.7-2.0
Bone: endosteal estimation1.22.54.02.01.72.01.7-1.71.01.7-1.70.21.81.31.5
Bone: endosteal perimeter1.73.65.02.22.11.92.1-2.11.42.1-2.1-0.22.21.71.9
Bone: final force0.40.73.50.3-0.31.6-0.30.3-1.0-0.30.31.9-0.1-0.7-0.4
Bone: final moment0.30.52.50.5-0.11.5-0.10.1-0.7-0.10.11.60.1-0.4-0.2
Bone: marrow area0.92.03.71.81.51.91.5-1.50.81.5-1.50.41.61.11.3
Bone: maximum diameter2.13.85.12.32.11.82.1-2.11.62.1-2.1-0.42.11.92.0
Bone: maximum force0.20.31.80.4-0.11.2-0.10.1-0.6-0.10.11.30.0-0.3-0.2
Bone: maximum moment0.10.21.00.50.11.00.1-0.1-0.20.1-0.10.90.2-0.10.0
Bone: minimum diameter0.71.33.61.51.11.91.1-1.10.41.1-1.10.81.20.70.9
Bone: periosteal estimation0.81.52.41.51.31.51.3-1.30.81.3-1.30.21.51.01.1
Bone: periosteal perimeter1.22.02.81.61.51.11.5-1.51.21.5-1.5-0.31.71.41.4
Bone: post-yield work0.10.10.30.40.30.10.3-0.30.50.3-0.3-0.30.30.40.3
Bone: stiffness0.81.26.20.6-0.32.3-0.30.3-1.3-0.30.32.5-0.1-0.8-0.4
Bone: tissue strength0.80.83.6-1.3-0.7-1.9-0.70.70.1-0.70.7-1.1-0.7-0.3-0.7
Bone: trabecular number1.32.02.8-1.7-1.6-1.2-1.61.6-1.1-1.61.60.3-1.5-1.3-1.6
Bone: trabecular spacing0.60.72.60.20.7-0.90.7-0.71.10.7-0.7-1.60.60.90.8
Bone: trabecular thickness0.50.63.20.70.31.80.3-0.3-0.50.3-0.31.60.4-0.3-0.1
Bone: trabecular tissue density1.41.99.40.5-0.62.5-0.60.6-1.7-0.60.63.1-0.5-1.2-0.6
Breakpoint value in progressive ratio session0.60.61.4-1.0-0.8-1.2-0.80.8-0.1-0.80.8-0.6-0.7-0.4-1.0
Distance traveled before self-admin0.70.81.1-1.0-1.0-1.0-1.01.0-0.6-1.01.0-0.0-0.7-0.8-0.8
Distance traveled after self-admin0.30.31.1-0.20.3-1.00.3-0.30.80.3-0.3-1.00.50.50.2
Delta time in closed arm before/after self-admin0.70.72.1-0.2-0.70.8-0.70.7-1.2-0.70.71.5-0.6-1.0-0.7
Delta time in open arm before/after self-admin2.92.83.71.91.71.81.7-1.71.51.7-1.7-0.41.91.71.9
Diff in mean of infusions in LGA sessions1.31.45.1-0.4-0.91.0-0.90.9-1.7-0.90.92.3-0.8-1.5-1.2
Extinction: sum of active levers before priming0.30.30.5-0.5-0.7-0.4-0.70.7-0.5-0.70.70.3-0.5-0.5-0.7
Active lever presses in extinction session 61.41.43.20.71.1-0.41.1-1.11.51.1-1.1-1.81.21.41.2
Delta distance traveled before/after self-admin2.42.63.31.81.81.31.8-1.81.41.8-1.8-0.41.61.61.5
Delta ambulatory time before/after self-admin1.71.92.41.51.60.81.6-1.61.31.6-1.6-0.51.41.51.3
Time in closed arm before self-admin1.82.04.51.01.3-0.41.3-1.32.01.3-1.3-2.11.21.81.5
Time in closed arm after self-admin0.50.50.6-0.6-0.8-0.2-0.80.8-0.8-0.80.80.5-0.8-0.7-0.7
Time in open arm before self-admin4.85.17.6-2.5-2.2-1.5-2.22.2-2.5-2.22.21.7-2.3-2.8-2.7
Time in open arm after self-admin0.10.10.50.40.20.70.2-0.2-0.20.2-0.20.60.4-0.00.2
Sum of active levers in priming session hrs 5-60.20.20.7-0.10.2-0.80.2-0.20.60.2-0.2-0.60.20.30.1
Time to tail flick, vehicle, before self-admin0.60.61.00.70.9-0.30.9-0.90.70.9-0.9-0.51.00.70.8
Time to tail flick, vehicle, after self-admin1.41.51.91.21.30.21.3-1.31.41.3-1.3-1.01.31.41.1
Time to tail flick, test, before self-admin2.82.83.61.81.91.41.9-1.91.21.9-1.9-0.41.91.51.9
Time to tail flick, test, after self-admin3.53.66.72.32.12.62.1-2.10.92.1-2.10.41.91.42.0
Delta time to tail flick, vehicle, before/after SA0.10.10.30.10.4-0.00.4-0.40.60.4-0.4-0.50.20.50.1
Delta time to tail flick, test, before/after SA0.10.10.2-0.2-0.20.1-0.20.2-0.4-0.20.20.3-0.3-0.3-0.3
Ambulatory time before self-admin1.01.11.4-1.2-1.2-0.9-1.21.2-0.8-1.21.20.1-1.0-1.0-1.1
Ambulatory time after self-admin0.20.30.70.20.5-0.50.5-0.50.80.5-0.5-0.80.40.60.2
Total heroin consumption0.70.91.80.60.9-0.50.9-0.91.20.9-0.9-1.31.01.10.7
Area under the delay curve0.70.81.5-0.6-0.80.4-0.80.8-1.1-0.80.81.2-0.9-1.0-0.8
Delay disc. indifference point, 0s delay0.50.60.70.60.80.40.8-0.80.80.8-0.8-0.50.80.70.7
Delay disc. indifference point, 16s delay0.90.92.7-0.2-0.81.2-0.80.8-1.2-0.80.81.6-0.7-0.9-0.6
Delay disc. indifference point, 2s delay0.30.31.30.80.41.20.4-0.40.20.4-0.40.50.40.40.6
Delay disc. indifference point, 24s delay2.12.03.1-0.9-1.50.4-1.51.5-1.8-1.51.51.7-1.4-1.6-1.3
Delay disc. indifference point, 4s delay0.70.71.51.00.91.20.9-0.90.60.9-0.90.30.90.60.8
Delay disc. indifference point, 8s delay0.60.60.9-0.7-0.8-0.1-0.80.8-0.8-0.80.80.7-0.9-0.8-0.9
Delay discount exponential model param1.01.01.40.81.0-0.31.0-1.01.21.0-1.0-1.21.01.11.0
Delay discount hyperbolic model param0.60.61.20.50.8-0.40.8-0.80.90.8-0.8-1.10.80.90.8
Fecal boli incidents, locomotor time 12.02.12.8-1.3-1.5-0.3-1.51.5-1.6-1.51.51.5-1.6-1.6-1.7
Change in fecal boli incidents, locomotor task0.10.10.10.2-0.20.4-0.20.20.1-0.20.2-0.3-0.10.20.3
Time >=10cm from walls, locomotor time 10.40.40.90.90.40.90.4-0.40.30.4-0.40.00.70.80.9
Bouts of movement, locomotor time 10.40.42.30.80.31.50.3-0.3-0.30.3-0.30.80.40.20.6
Total resting periods, locomotor time 10.20.20.80.2-0.30.9-0.30.3-0.6-0.30.30.6-0.2-0.2-0.0
Rest time, locomotor task time 10.10.10.50.3-0.20.7-0.20.2-0.3-0.20.20.5-0.4-0.00.0
Distance moved, locomotor task time 10.00.00.1-0.10.2-0.30.2-0.20.20.2-0.2-0.20.30.10.0
Vertical activity count, locomotor time 10.00.00.1-0.00.20.30.2-0.20.00.2-0.20.30.3-0.2-0.1
Time >=10cm from walls, locomotor time 22.62.74.62.21.62.01.6-1.61.21.6-1.60.11.61.62.0
Bouts of movement, locomotor time 20.70.84.40.9-0.02.1-0.00.0-0.8-0.00.01.90.1-0.20.0
Total resting periods, locomotor time 20.80.93.90.3-0.61.7-0.60.6-1.2-0.60.62.0-0.4-0.7-0.5
Rest time, locomotor task time 23.33.84.8-2.0-2.2-1.2-2.22.2-1.8-2.22.20.9-2.2-1.9-2.1
Distance moved, locomotor task time 22.73.14.11.81.81.01.8-1.81.81.8-1.8-1.11.91.92.0
Vertical activity count, locomotor time 20.50.51.50.80.81.20.8-0.80.40.8-0.80.40.70.40.6
Weight adjusted by age2.02.33.21.41.80.71.8-1.81.31.8-1.8-0.61.51.41.6
Seeking ratio, delayed vs. immediate footshock2.42.73.5-1.7-1.9-1.3-1.91.9-1.6-1.91.90.6-1.7-1.5-1.6
Locomotion in novel chamber0.60.83.5-1.1-0.7-1.9-0.70.7-0.3-0.70.7-0.9-0.8-0.4-0.7
Locomotion in novel chamber post-restriction0.30.31.50.20.2-0.40.2-0.20.90.2-0.2-1.20.40.80.5
Progressive ratio0.10.10.7-0.2-0.1-0.4-0.10.10.3-0.10.1-0.8-0.00.20.3
Food seeking constrained by brief footshock1.82.13.71.91.41.41.4-1.41.21.4-1.4-0.41.51.61.8
Seeking ratio, punishment vs. effort0.70.91.61.31.01.21.0-1.00.61.0-1.00.31.00.80.7
Run reversals in cocaine runway, females0.40.40.50.70.70.30.7-0.70.60.7-0.7-0.20.60.60.6
Run reversals in cocaine runway, males0.50.50.6-0.7-0.70.1-0.70.7-0.8-0.70.70.7-0.7-0.8-0.5
Latency to leave start box in cocaine runway1.11.22.3-1.2-1.00.0-1.01.0-1.1-1.01.01.1-1.1-1.4-1.5
Latency to leave start box in cocaine runway, F0.70.82.1-0.6-0.70.6-0.70.7-1.0-0.70.71.5-0.7-1.2-1.1
Latency to leave start box in cocaine runway, M1.21.21.7-1.3-1.2-0.7-1.21.2-0.8-1.21.20.2-1.2-1.0-1.3
Cd content in liver0.80.91.2-0.8-1.0-0.4-1.01.0-1.0-1.01.00.9-1.1-1.0-1.0
Co content in liver2.52.96.42.21.72.51.7-1.70.91.7-1.70.61.61.41.8
Cu content in liver1.21.43.21.61.21.81.2-1.20.61.2-1.20.51.21.01.2
Fe content in liver0.20.21.10.4-0.01.0-0.00.0-0.5-0.00.01.00.0-0.3-0.0
K content in liver0.50.50.9-0.6-0.8-0.1-0.80.8-0.9-0.80.80.7-0.7-0.8-0.8
Mg content in liver0.00.00.1-0.00.1-0.10.1-0.10.10.1-0.1-0.30.10.10.1
Mn content in liver2.73.14.2-2.0-1.9-1.7-1.91.9-1.4-1.91.90.3-1.8-1.6-1.9
Na content in liver0.10.10.20.30.30.00.3-0.30.40.3-0.3-0.40.50.50.5
Rb content in liver0.40.51.01.00.61.00.6-0.60.30.6-0.60.10.80.70.9
Se content in liver5.06.07.2-2.3-2.6-1.1-2.62.6-2.6-2.62.61.7-2.6-2.6-2.7
Sr content in liver0.60.52.8-0.50.1-1.40.1-0.10.80.1-0.1-1.70.10.50.1
Zn content in liver2.62.84.61.21.7-0.21.7-1.72.11.7-1.7-2.11.52.01.7