Hub : Genes

Csnk1d

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative polyA ENSRNOT00000099055 0.03 0.02 1.1e-03 0.02 0.02 0.01 0.01 2.0e-03 2.7e-03 7.9e-03 8.2e-03
2 Adipose alternative polyA ENSRNOT00000106442 0.03 0.02 1.6e-03 0.01 0.02 0.01 0.01 7.1e-03 4.4e-03 1.2e-02 1.5e-02
3 Adipose isoform ratio ENSRNOT00000054936 0.03 0.02 9.0e-04 0.02 0.03 0.01 0.01 6.2e-03 7.6e-04 9.4e-03 1.1e-02
4 Brain mRNA stability ENSRNOG00000036676 0.07 0.05 5.9e-06 0.04 0.05 0.04 0.05 1.6e-04 2.3e-05 5.6e-05 4.4e-05
5 Liver alternative polyA ENSRNOT00000099055 0.05 0.04 5.7e-04 0.01 0.02 0.01 0.01 3.2e-02 1.7e-03 1.1e-02 7.6e-03
6 Liver alternative polyA ENSRNOT00000106442 0.05 0.04 1.6e-03 0.01 0.02 0.01 0.01 6.3e-02 4.3e-03 3.9e-02 3.0e-02
7 Liver gene expression ENSRNOG00000036676 0.02 0.01 1.2e-03 0 0.02 0.01 0 1.2e-01 5.7e-03 7.8e-03 8.3e-02
8 Liver intron excision ratio chr10:106227740:106228787 0.03 0.02 9.8e-03 0.01 0.01 0 0 5.9e-02 4.4e-02 1.1e-01 1.4e-01
9 NAcc alternative TSS ENSRNOT00000015178 0.04 0.03 1.4e-03 0.02 0.03 0.01 0.02 6.6e-03 3.1e-03 6.9e-02 8.1e-03
10 PL alternative polyA ENSRNOT00000099055 0.07 0.05 1.6e-04 0.05 0.05 0.02 0.04 1.8e-04 2.0e-04 1.0e-02 2.6e-04
11 PL alternative polyA ENSRNOT00000106442 0.08 0.05 1.9e-04 0.04 0.05 0.04 0.04 4.2e-04 8.9e-05 9.7e-04 6.5e-04
12 PL alternative polyA ENSRNOT00000099055 0.09 0.06 1.1e-04 0.04 0.05 0.03 0.04 3.1e-04 7.8e-05 3.8e-03 8.4e-04
13 PL alternative polyA ENSRNOT00000106442 0.09 0.05 7.1e-05 0.05 0.05 0.03 0.04 1.3e-04 6.7e-05 3.0e-03 4.1e-04
14 PL gene expression ENSRNOG00000036676 0.04 0.03 2.5e-03 0.03 0.03 0.02 0.02 5.1e-03 4.4e-03 1.0e-02 9.8e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
BMI with tail0.51.74.41.4-1.2-1.21.71.9-2.10.8-1.5-0.91.9-0.40.3-0.3-0.6
BMI without tail7.215.022.44.2-4.5-3.84.72.8-3.02.6-4.4-3.64.3-3.83.8-3.7-4.0
Body weight2.912.324.14.1-3.7-4.04.24.7-4.93.5-4.1-3.73.0-0.90.7-0.7-3.0
Epididymis fat weight0.92.14.01.6-1.6-1.51.81.3-1.31.0-1.6-1.42.0-1.21.1-1.1-1.4
Glucose5.38.116.0-2.43.02.0-3.4-0.70.8-0.82.72.0-4.03.9-3.93.92.7
Heart weight0.40.62.30.8-0.6-0.80.71.4-1.50.9-0.9-0.70.30.3-0.30.3-0.4
Left kidney weight0.20.51.60.00.4-0.0-0.01.0-1.10.2-0.00.1-0.41.2-1.31.20.6
Right kidney weight0.10.40.9-0.20.50.3-0.10.6-0.8-0.30.20.50.00.9-1.00.90.9
Tail length6.018.226.04.8-5.1-4.65.13.4-3.53.7-4.9-4.63.7-3.63.6-3.5-4.9
Length with tail1.76.110.92.9-2.6-3.02.83.2-3.32.8-2.8-3.01.3-0.30.2-0.2-2.4
Length without tail2.14.513.2-1.32.01.0-1.80.7-0.7-0.21.61.1-2.33.5-3.63.62.2
Liver weight, left0.61.03.0-0.70.90.4-1.00.3-0.20.10.80.3-1.31.7-1.71.70.8
Liver weight, right1.21.93.51.6-1.4-1.61.61.8-1.91.5-1.5-1.60.9-0.20.2-0.2-1.3
Parametrial fat weight1.32.63.81.9-1.8-1.91.81.7-1.71.8-1.9-2.01.0-0.80.7-0.7-1.9
Retroperitoneal fat weight3.511.716.33.9-3.9-4.03.93.4-3.43.6-3.9-4.02.8-2.01.9-1.8-4.0
Intraocular pressure0.91.31.91.3-1.4-1.11.30.8-0.80.9-1.3-1.10.9-1.11.1-1.0-1.3
Extensor digitorum longus weight0.41.44.60.6-1.0-0.41.2-0.20.1-0.3-0.9-0.32.1-1.91.9-1.9-0.7
Soleus weight1.33.75.02.2-2.2-2.22.21.8-1.81.9-2.2-2.21.6-1.31.3-1.2-2.2
Tibialis anterior weight0.20.71.90.5-0.7-0.40.7-0.20.20.0-0.6-0.41.1-1.41.4-1.4-0.8
Tibia length6.819.046.05.0-3.9-5.14.26.6-6.85.4-4.7-4.90.91.0-1.21.2-3.6
Number of licking bursts0.30.41.00.3-0.6-0.30.7-0.10.00.0-0.5-0.31.0-0.90.9-0.9-0.5
Food consumed during 24 hour testing period0.40.40.90.7-0.8-0.70.70.4-0.30.7-0.7-0.80.5-0.60.6-0.6-0.9
Times rat made contact with spout0.91.03.20.8-0.9-1.30.40.9-0.71.8-0.8-1.5-0.90.2-0.10.2-1.6
Mean time between licks in bursts1.21.72.8-1.51.41.6-1.3-1.61.6-1.71.51.6-0.60.3-0.20.21.5
Mean num. licks in bursts0.30.41.30.3-0.1-0.6-0.20.6-0.41.0-0.2-0.7-1.10.7-0.70.7-0.6
Std. dev. time between licks in bursts2.02.47.51.0-1.4-0.61.80.0-0.2-0.3-1.3-0.52.7-2.42.3-2.4-0.9
Water consumed over 24 hours0.30.31.2-0.50.50.2-0.7-0.20.30.20.50.1-1.10.8-0.80.80.2
Indifference point 0 sec0.00.00.10.1-0.3-0.30.30.2-0.10.3-0.2-0.30.0-0.10.1-0.1-0.3
Indifference point AUC0.10.10.30.3-0.3-0.20.20.0-0.00.2-0.4-0.20.3-0.50.5-0.5-0.4
Indifference point function ln k0.81.22.3-1.21.21.3-1.0-1.01.0-1.41.21.4-0.40.6-0.60.61.5
Indifference point function log k0.81.22.3-1.21.21.3-1.0-1.01.0-1.41.21.4-0.40.6-0.60.61.5
Delay discounting total patch changes 0 sec0.00.10.10.1-0.3-0.30.40.2-0.10.2-0.2-0.30.1-0.20.2-0.2-0.3
Delay discounting total patch changes 12 sec0.00.00.20.1-0.2-0.30.10.2-0.10.4-0.1-0.3-0.40.1-0.00.1-0.3
Delay discounting total patch changes 18 sec0.20.20.7-0.0-0.20.10.2-0.50.4-0.4-0.10.20.6-0.80.8-0.8-0.1
Delay discounting total patch changes 24 sec0.40.50.70.7-0.8-0.80.80.7-0.70.7-0.8-0.80.5-0.50.5-0.4-0.8
Delay discounting total patch changes 6 sec0.20.40.80.5-0.6-0.80.60.7-0.60.9-0.6-0.8-0.1-0.00.0-0.0-0.8
Delay discounting time to switch 0 sec0.40.61.2-1.00.90.9-0.9-1.01.1-0.81.00.8-0.60.3-0.30.30.7
Delay discounting water rate 0 sec2.03.25.02.1-2.1-2.02.21.9-2.01.5-2.1-1.91.7-1.11.1-1.1-1.7
Delay discounting water rate 12 sec0.40.51.70.8-0.7-0.41.00.7-0.90.0-0.9-0.31.3-0.60.6-0.6-0.2
Delay discounting water rate 18 sec0.81.13.00.9-1.1-0.81.40.7-0.80.2-1.1-0.61.7-1.21.2-1.2-0.7
Delay discounting water rate 24 sec2.23.06.01.9-2.0-1.52.21.4-1.60.8-2.0-1.32.4-1.71.6-1.6-1.4
Delay discounting water rate 6 sec0.10.20.90.4-0.3-0.10.60.6-0.8-0.2-0.40.11.0-0.10.0-0.10.4
Locomotor activity0.61.01.5-1.21.21.1-1.1-1.01.1-1.01.21.1-0.80.6-0.50.51.1
Locomotor testing distance0.91.42.4-1.51.21.4-1.1-1.61.6-1.51.41.4-0.30.1-0.10.01.3
Locomotor testing rearing0.30.51.6-0.80.50.8-0.6-1.21.3-0.90.70.70.0-0.50.5-0.50.4
Light reinforcement 11.42.66.01.4-1.8-1.31.80.7-0.70.8-1.6-1.32.4-1.91.9-1.9-1.7
Light reinforcement 21.92.53.91.9-1.8-1.61.91.3-1.41.2-1.8-1.62.0-1.31.2-1.2-1.6
Reaction time number correct2.23.19.60.8-1.2-0.11.5-0.70.4-0.9-1.00.03.1-2.92.9-3.0-0.6
Reaction time mean minus median0.30.40.9-0.70.70.4-0.9-0.30.40.00.70.3-0.90.9-0.90.90.4
Reaction time mean minus median AUC0.00.00.1-0.10.20.1-0.3-0.00.10.10.20.0-0.20.3-0.30.30.1
Reaction time num false alarms0.20.20.5-0.70.50.5-0.6-0.60.6-0.40.50.5-0.40.1-0.10.10.4
Reaction time num false alarms AUC0.50.61.2-1.00.80.9-0.8-1.11.1-0.90.90.9-0.4-0.00.0-0.00.7
Reaction time trials correct on left2.23.19.60.8-1.2-0.11.5-0.70.4-0.9-1.00.03.1-2.92.9-3.0-0.6
Reaction time trials on left2.33.29.90.8-1.2-0.11.6-0.70.5-1.0-1.10.03.1-3.03.0-3.0-0.6
Reaction time mean0.20.30.60.6-0.6-0.60.50.4-0.50.5-0.6-0.60.8-0.40.4-0.4-0.7
Reaction time mean AUC0.30.41.30.5-0.6-0.50.60.2-0.20.3-0.6-0.41.2-0.80.8-0.8-0.6
Median of all reaction times0.30.41.10.7-0.7-0.60.70.5-0.50.4-0.7-0.61.0-0.60.6-0.6-0.7
Reaction time omissions0.20.20.70.2-0.4-0.20.4-0.30.3-0.1-0.2-0.20.7-0.80.8-0.8-0.4
Reaction time false alarm rate1.01.43.5-1.31.30.9-1.5-0.60.8-0.31.30.8-1.91.4-1.41.40.9
Reaction time premature initiation rate0.81.11.6-1.01.11.2-1.2-1.21.3-1.11.21.2-1.20.4-0.30.31.1
Reaction time premature initiations0.71.02.1-0.40.31.0-0.2-1.41.3-1.40.41.00.6-1.31.3-1.30.6
Std. dev. reaction times0.20.30.7-0.70.60.6-0.7-0.80.8-0.60.70.6-0.10.1-0.10.10.5
Reaction time trials completed2.33.29.90.8-1.2-0.11.6-0.70.5-1.0-1.10.03.1-3.03.0-3.0-0.6
Reaction time trials AUC2.23.210.00.8-1.3-0.21.6-0.60.4-0.9-1.1-0.03.2-3.03.0-3.0-0.7
Social response proportion0.30.41.0-0.60.60.8-0.4-0.60.5-1.00.60.9-0.10.1-0.20.11.0
Social responses0.20.30.8-0.70.50.7-0.2-0.50.4-0.90.50.70.30.1-0.20.10.9
Social time0.10.10.4-0.40.40.5-0.1-0.20.1-0.70.30.60.2-0.0-0.0-0.00.6
Conditioned locomotion4.75.57.92.6-2.7-2.52.82.0-2.11.9-2.7-2.42.4-2.01.9-1.9-2.6
Cocaine response after cond. corrected0.20.30.9-0.20.40.2-0.40.1-0.00.00.40.2-0.90.8-0.80.80.4
Cocaine response after cond. not corrected0.50.61.2-0.60.80.7-0.8-0.50.5-0.50.80.7-1.10.8-0.80.80.9
Cocaine response before conditioning0.70.81.7-1.00.81.1-0.6-1.31.2-1.30.91.10.1-0.30.3-0.30.9
Saline control response2.63.44.82.2-2.2-2.22.21.9-1.91.9-2.1-2.21.3-1.01.0-1.0-2.1
Condit. Reinf. active minus inactive responses1.01.32.41.4-1.2-1.21.31.4-1.51.1-1.4-1.10.9-0.50.5-0.4-1.0
Condit. Reinf. active-inactive response ratio2.12.24.51.8-1.5-1.81.52.1-2.11.8-1.7-1.70.4-0.00.00.0-1.4
Condit. Reinf. active responses0.40.50.90.9-0.8-0.70.90.8-0.90.5-0.9-0.60.8-0.50.5-0.5-0.6
Condit. Reinf. inactive responses0.30.30.8-0.60.50.8-0.5-0.70.6-0.90.50.80.1-0.10.1-0.10.7
Condit. Reinf. lever presses0.40.51.00.7-0.8-0.50.90.3-0.40.2-0.8-0.51.0-0.90.9-0.9-0.7
Condit. Reinf. lever reinforcers received0.40.60.90.9-0.9-0.71.00.7-0.80.4-1.0-0.61.0-0.80.8-0.8-0.6
Pavlov. Cond. lever latency1.01.32.5-1.01.30.9-1.3-0.40.4-0.51.20.9-1.61.5-1.51.51.2
Pavlov. Cond. magazine entry latency1.31.53.6-1.20.81.4-0.7-1.91.9-1.71.11.40.4-0.90.9-0.90.9
Pavlov. Cond. change in total contacts0.20.30.8-0.2-0.10.30.1-0.70.7-0.70.10.40.9-0.90.9-0.90.1
Pavlov. Cond. index score0.30.41.1-0.1-0.10.30.2-0.80.7-0.60.00.30.8-1.01.1-1.1-0.1
Pavlov. Cond. latency score0.40.51.6-0.0-0.30.20.3-0.70.7-0.6-0.10.21.0-1.21.3-1.3-0.2
Pavlov. Cond. lever contacts1.52.13.71.3-1.6-1.21.60.5-0.50.7-1.5-1.11.9-1.91.9-1.8-1.5
Pavlov. Cond. magazine entry number1.01.33.01.0-0.6-1.20.51.7-1.71.6-0.9-1.2-0.61.0-1.01.0-0.8
Pavlov. Cond. intertrial magazine entries1.82.33.51.9-1.7-1.71.71.8-1.81.6-1.9-1.71.0-0.70.7-0.7-1.6
Pavlov. Cond. lever-magazine prob. diff.0.40.51.1-0.3-0.00.40.0-0.90.9-0.70.20.40.7-1.01.0-1.00.0
Pavlov. Cond. response bias0.50.71.80.5-0.7-0.30.8-0.20.2-0.1-0.6-0.31.3-1.31.3-1.3-0.6
Conditioned reinforcement - actives0.30.30.80.2-0.3-0.00.4-0.30.3-0.3-0.2-0.00.9-0.90.9-0.9-0.2
Conditioned reinforcement - inactives0.91.01.81.2-1.1-1.31.11.3-1.31.2-1.1-1.20.4-0.10.1-0.0-1.0
Conditioned locomotion0.10.10.20.0-0.2-0.10.2-0.10.1-0.0-0.2-0.10.4-0.40.4-0.4-0.2
Intermittent access intake day 1-15 change0.80.81.51.2-1.1-1.10.90.8-0.71.1-0.9-1.20.3-0.40.4-0.4-1.2
Intermittent access intake escalation0.80.81.61.1-1.1-1.11.00.5-0.51.0-0.9-1.20.5-0.70.7-0.7-1.2
Intermittent access intake escalation 21.31.33.11.2-1.1-1.50.81.5-1.41.8-1.0-1.60.10.4-0.40.5-1.3
Intermitt. access day 1 inactive lever presses0.70.81.51.0-0.9-1.10.81.2-1.21.2-0.9-1.10.10.3-0.30.3-0.8
Intermitt. access day 15 inactive lever presses1.01.11.81.2-1.3-1.11.30.8-0.80.8-1.2-1.01.1-1.01.0-1.0-1.1
Intermitt. access escalation Index1.71.53.11.1-1.3-0.91.30.2-0.20.4-1.2-0.91.4-1.81.8-1.7-1.3
Intermittent access day 1 total infusions0.40.50.70.7-0.8-0.70.90.7-0.70.6-0.8-0.70.6-0.50.4-0.4-0.7
Intermittent access day 15 total infusions0.91.01.51.1-1.2-1.11.20.7-0.60.9-1.1-1.10.9-0.90.9-0.9-1.2
Intermittent access terminal intake (last 3 days)1.21.32.21.3-1.4-1.41.20.9-0.91.2-1.2-1.40.8-0.70.7-0.7-1.5
Intermittent access total infusions0.70.81.21.0-1.1-1.01.10.7-0.70.7-1.0-1.00.8-0.80.7-0.7-1.0
Intermittent access day 1 locomotion0.30.30.80.7-0.7-0.50.90.5-0.50.2-0.7-0.40.8-0.60.5-0.5-0.4
Intermittent access day 15 total locomotion0.40.40.60.7-0.7-0.80.70.7-0.70.7-0.7-0.80.2-0.20.2-0.2-0.7
Intermittent access total locomotion0.30.40.70.8-0.7-0.70.90.7-0.70.5-0.7-0.70.5-0.30.2-0.3-0.5
Intermittent access standard deviation1.41.54.1-0.91.10.6-1.20.10.0-0.11.10.5-1.42.0-2.02.01.1
Cocaine induced anxiety3.23.68.71.5-1.1-2.11.02.9-2.92.7-1.4-2.1-0.71.8-1.81.9-1.2
Post-drug Anxiety0.80.92.20.4-0.0-0.6-0.01.3-1.21.0-0.2-0.6-1.11.4-1.51.5-0.0
Baseline Anxiety5.05.39.6-2.42.32.9-2.1-3.03.0-3.12.42.9-0.9-0.10.1-0.22.5
Lifetime Intake0.20.20.40.5-0.6-0.50.60.2-0.20.3-0.5-0.50.5-0.50.5-0.5-0.6
Incentive Sensitization - Responses0.50.50.90.9-0.8-0.70.70.4-0.40.7-0.8-0.80.1-0.60.7-0.6-1.0
Incentive Sensitization - Breakpoint0.30.30.70.8-0.7-0.60.50.4-0.40.7-0.7-0.70.0-0.50.5-0.5-0.9
Progressive ratio test 1 active lever presses1.21.21.81.1-1.3-1.21.30.8-0.81.0-1.2-1.31.2-0.90.9-0.9-1.3
Progressive ratio test 1 breakpoint1.61.62.41.3-1.5-1.41.51.0-1.01.2-1.4-1.51.3-1.01.0-1.0-1.6
Progressive ratio test 1 inactive lever presses2.22.33.51.7-1.8-1.71.91.5-1.61.4-1.8-1.71.6-0.90.9-0.9-1.6
Progressive ratio test 2 active lever presses0.50.50.90.9-0.9-0.80.80.6-0.60.7-0.8-0.90.4-0.60.6-0.5-0.9
Progressive ratio test 2 breakpoint0.70.81.21.0-1.1-0.91.10.5-0.50.7-1.0-0.90.7-0.90.9-0.9-1.1
Progressive ratio test 2 inactive lever presses0.30.40.70.7-0.6-0.70.60.8-0.80.7-0.7-0.70.10.0-0.00.1-0.6
Total sessions with >9 infusions0.20.20.4-0.40.40.5-0.3-0.50.5-0.70.40.60.1-0.10.1-0.10.5
Short access day 1 total inactive lever presses0.40.41.30.2-0.30.20.5-0.50.4-0.6-0.20.20.9-1.11.1-1.1-0.0
Short access day 10 total inactive lever presses2.93.25.62.2-1.9-2.12.02.3-2.42.0-2.0-2.10.7-0.20.2-0.1-1.7
Short access day 1 total infusions1.71.82.6-1.61.51.5-1.5-1.41.4-1.41.61.5-0.70.7-0.70.71.6
Short access day 10 total infusions0.40.40.90.6-0.8-0.90.70.7-0.60.9-0.7-0.90.4-0.20.1-0.1-0.9
Short access total infusions0.00.00.0-0.0-0.1-0.00.0-0.10.10.0-0.0-0.10.2-0.10.1-0.1-0.1
Short access day 1 locomotion0.70.71.1-1.01.00.8-1.0-0.40.4-0.50.90.8-0.71.0-1.01.01.0
Short access day 10 total locomotion0.60.61.7-0.50.70.4-0.70.1-0.1-0.00.60.3-1.01.3-1.31.30.7
Short access total locomotion0.60.61.0-0.80.90.7-0.8-0.30.3-0.50.80.7-0.71.0-1.01.00.9
Compulsive drug intake0.40.40.50.7-0.6-0.60.70.7-0.70.5-0.7-0.60.7-0.40.4-0.4-0.6
One hour access (0.3 mA shock)1.82.13.01.6-1.7-1.61.71.1-1.11.3-1.6-1.61.2-1.31.3-1.3-1.7
One hour access (shock baseline)0.50.61.30.7-0.8-0.50.80.0-0.00.3-0.7-0.60.8-1.11.1-1.1-0.8
Number of responses in last shaping day0.50.51.10.8-0.7-0.70.91.0-1.10.5-0.8-0.60.8-0.20.1-0.2-0.4
Context. condit. distance diff. score1.62.05.21.0-1.4-0.81.50.1-0.20.1-1.3-0.72.3-2.12.1-2.1-1.1
Locomotion velocity, session 12.83.05.3-1.82.01.6-2.2-1.01.1-0.91.91.5-2.31.9-1.91.91.7
Locomotion distance, session 11.72.24.7-1.61.41.9-1.2-1.91.8-2.21.52.0-0.0-0.30.3-0.31.7
Locomotion velocity, session 24.14.86.5-2.52.52.5-2.5-2.22.2-2.32.52.5-1.71.3-1.31.22.5
Locomotion distance, session 20.30.41.1-0.30.20.70.0-0.70.6-1.00.20.80.6-0.70.7-0.70.6
Locomotion velocity, session 32.42.83.9-2.02.01.7-1.9-1.21.2-1.41.91.7-1.61.6-1.61.62.0
Locomotion distance, session 33.23.55.5-2.22.12.2-1.9-1.71.7-2.12.12.2-1.21.2-1.21.12.3
Stereotopy head waving bouts, day 30.70.91.3-1.01.10.9-1.1-0.50.5-0.51.00.9-1.11.0-1.01.01.0
Stereotopy head waving duration, day 30.30.40.6-0.80.80.7-0.8-0.40.4-0.50.70.7-0.60.6-0.60.60.7
Locomotion velocity, session 70.70.71.3-1.10.91.0-0.8-1.11.2-1.11.01.0-0.20.1-0.10.10.9
Locomotion distance, session 72.02.55.4-1.71.31.9-1.1-2.32.2-2.31.52.00.5-0.70.7-0.81.6
Stereotopy head waving bouts, day 70.10.10.30.2-0.3-0.40.40.5-0.50.3-0.4-0.30.4-0.10.0-0.0-0.3
Stereotopy head waving duration, day 70.20.20.60.4-0.4-0.60.50.7-0.70.6-0.5-0.60.30.0-0.10.1-0.5
Locomotion velocity, session 80.40.51.2-0.20.10.60.2-0.60.5-1.10.10.80.9-0.90.9-0.90.6
Locomotion distance, session 81.82.68.30.8-1.2-0.31.6-0.40.1-0.7-1.1-0.12.9-2.72.7-2.7-0.7
Degree of sensitization distance1.41.42.61.1-1.3-0.91.20.3-0.30.6-1.2-1.01.4-1.61.6-1.6-1.3
Degree of sensitization stereotypy0.30.40.70.6-0.6-0.70.70.8-0.80.5-0.7-0.60.7-0.30.2-0.2-0.5
Condit. Reinf. active minus inactive responses2.32.54.02.0-1.8-1.81.81.7-1.71.6-1.9-1.81.2-0.90.9-0.9-1.7
Condit. Reinf. active-inactive response ratio0.80.91.41.2-1.0-1.11.11.1-1.20.9-1.1-1.00.7-0.40.3-0.3-0.9
Condit. Reinf. active responses4.35.27.92.8-2.6-2.62.62.2-2.32.2-2.7-2.51.8-1.51.5-1.5-2.6
Condit. Reinf. inactive responses1.41.62.41.5-1.5-1.41.41.0-1.01.2-1.5-1.40.9-1.01.0-1.0-1.6
Incentive salience index mean1.82.23.41.8-1.7-1.61.71.3-1.41.3-1.7-1.61.3-1.11.1-1.1-1.7
Condit. Reinf. lever presses0.20.31.00.2-0.3-0.00.4-0.50.5-0.3-0.2-0.00.9-1.01.0-1.0-0.3
Time in familiar zone, hab. session 10.20.20.50.00.20.0-0.30.4-0.40.20.10.0-0.70.7-0.70.70.2
Time in novel zone, hab. session 10.10.10.3-0.0-0.2-0.00.2-0.20.2-0.2-0.1-0.00.5-0.50.5-0.5-0.1
Total zone transitions, hab. session 10.20.20.6-0.50.50.7-0.4-0.50.5-0.80.50.70.2-0.10.1-0.10.7
Total locomotion distance, hab. session 10.20.31.10.3-0.4-0.20.60.0-0.1-0.1-0.4-0.11.0-0.80.7-0.8-0.2
Locomotion velocity, hab. session 10.20.31.10.3-0.4-0.20.60.0-0.1-0.1-0.4-0.11.1-0.80.8-0.8-0.3
Time in familiar zone, hab. session 20.20.20.5-0.50.30.5-0.3-0.70.7-0.60.40.50.0-0.30.3-0.30.3
Time in novel zone, hab. session 20.00.00.1-0.10.20.2-0.10.1-0.1-0.10.10.2-0.00.2-0.20.20.3
Total zone transitions, hab. session 20.70.92.60.1-0.30.30.6-0.60.5-0.9-0.30.51.5-1.61.6-1.60.0
Total locomotion distance, hab. session 21.52.05.41.1-1.3-0.61.50.0-0.2-0.1-1.2-0.52.3-2.22.2-2.2-1.0
Locomotion velocity, hab. session 21.72.35.61.3-1.5-0.91.80.3-0.50.2-1.5-0.82.4-2.22.2-2.2-1.2
Novel to familiar place preference ratio2.02.14.91.5-1.1-1.71.12.2-2.22.0-1.3-1.7-0.30.8-0.90.9-1.2
Novelty place preference2.02.14.81.5-1.1-1.71.02.2-2.22.0-1.3-1.7-0.40.9-0.91.0-1.1
Time in novel zone, NPP test1.61.73.91.4-1.0-1.51.02.0-2.01.8-1.2-1.5-0.20.7-0.70.8-1.1
Total zone transitions, NPP test1.11.64.2-0.2-0.20.60.5-1.31.1-1.4-0.10.71.8-2.02.0-2.10.1
Total locomotion distance, NPP test1.52.16.30.6-1.0-0.11.3-0.60.5-0.7-0.8-0.12.5-2.52.5-2.5-0.7
Locomotion velocity, NPP test1.21.74.90.7-1.1-0.41.3-0.30.2-0.4-0.9-0.32.2-2.12.1-2.1-0.8
Pavlov. Cond. lever latency0.70.92.0-0.70.30.9-0.1-1.21.1-1.40.41.01.1-1.21.2-1.20.6
Pavlov. Cond. magazine entry latency1.72.14.71.6-1.0-1.70.92.1-2.02.2-1.2-1.8-0.81.0-1.01.0-1.3
Pavlov. Cond. change in total contacts0.80.82.40.00.3-0.3-0.50.8-0.70.80.2-0.3-1.51.5-1.51.50.1
Pavlov. Cond. index score1.92.55.11.8-1.4-2.01.22.1-2.02.3-1.5-2.0-0.20.5-0.50.5-1.7
Pavlov. Cond. latency score1.51.94.31.5-1.1-1.70.91.9-1.82.1-1.2-1.8-0.50.7-0.70.8-1.4
Pavlov. Cond. lever contacts0.40.41.00.7-0.4-0.80.30.8-0.81.0-0.4-0.9-0.40.5-0.50.5-0.7
Pavlov. Cond. magazine entry number1.82.24.7-1.20.71.5-0.4-2.12.0-2.20.91.61.3-1.61.6-1.61.0
Pavlov. Cond. intertrial magazine entries0.81.02.00.8-1.0-0.61.10.2-0.30.2-1.0-0.61.4-1.41.4-1.4-0.9
Pavlov. Cond. lever-magazine prob. diff.2.02.55.21.8-1.4-2.01.32.2-2.22.3-1.5-2.0-0.20.6-0.60.6-1.6
Pavlov. Cond. response bias1.41.83.81.2-0.7-1.50.61.9-1.81.9-0.9-1.5-1.01.2-1.21.3-1.0
Bone: apparent density0.20.40.70.6-0.6-0.50.80.3-0.30.2-0.6-0.40.8-0.80.7-0.7-0.6
Bone surface0.20.40.80.6-0.7-0.70.60.3-0.30.7-0.6-0.80.4-0.50.5-0.5-0.9
Bone volume0.30.40.70.7-0.8-0.70.80.4-0.30.6-0.7-0.70.6-0.70.7-0.7-0.9
Bone: connectivity density0.30.51.50.2-0.4-0.00.5-0.50.4-0.4-0.30.01.1-1.21.2-1.2-0.4
Bone: cortical apparent density2.53.34.8-2.22.12.0-2.1-1.81.8-1.72.12.0-1.41.2-1.11.12.0
Bone: cortical area4.66.919.93.1-2.2-2.92.94.2-4.52.8-2.9-2.61.20.5-0.70.7-1.6
Bone: cortical porosity1.71.84.70.30.2-0.7-0.41.5-1.41.5-0.0-0.8-1.92.1-2.12.2-0.1
Bone: cortical porosity1.31.42.80.6-0.1-0.9-0.01.6-1.51.5-0.3-1.0-1.41.6-1.61.7-0.4
Bone: cortical thickness4.26.923.42.7-1.7-2.62.34.6-4.82.8-2.5-2.30.31.7-1.91.8-1.0
Bone: cortical thickness1.61.96.91.4-0.7-1.21.22.5-2.61.3-1.2-1.00.21.0-1.11.1-0.3
Bone: cortical tissue density2.93.75.5-2.42.22.2-2.3-2.02.1-1.82.32.1-1.51.2-1.21.12.1
Bone: elastic displacement0.91.02.31.0-0.8-1.20.91.5-1.51.3-1.0-1.2-0.00.3-0.40.4-0.9
Bone: elastic work5.26.816.92.7-1.9-3.02.14.1-4.13.5-2.4-2.9-0.41.4-1.51.5-2.0
Bone: endosteal estimation0.30.72.00.2-0.6-0.10.6-0.50.5-0.3-0.4-0.11.2-1.41.4-1.4-0.5
Bone: endosteal perimeter0.51.01.71.2-1.2-1.21.10.9-0.81.1-1.1-1.30.6-0.60.6-0.6-1.3
Bone: final force4.37.119.53.2-2.4-2.93.04.2-4.42.8-3.0-2.71.40.3-0.40.4-1.8
Bone: final moment4.98.021.63.3-2.6-3.23.14.4-4.63.1-3.2-2.91.20.4-0.60.6-2.0
Bone: marrow area0.30.61.90.2-0.6-0.10.6-0.50.5-0.3-0.4-0.11.2-1.31.4-1.4-0.5
Bone: maximum diameter1.01.94.61.7-1.3-1.51.62.0-2.11.4-1.5-1.40.9-0.0-0.10.0-1.0
Bone: maximum force4.68.120.73.4-2.7-3.13.34.3-4.62.9-3.3-2.81.7-0.0-0.10.1-2.0
Bone: maximum moment5.18.922.63.5-2.8-3.43.34.5-4.83.2-3.4-3.11.60.1-0.20.2-2.2
Bone: minimum diameter2.13.87.82.3-1.9-2.42.22.7-2.82.3-2.2-2.20.9-0.1-0.00.0-1.8
Bone: periosteal estimation1.53.16.52.1-1.8-2.02.22.4-2.51.7-2.1-1.81.4-0.50.4-0.4-1.4
Bone: periosteal perimeter2.23.69.22.1-1.5-2.21.63.0-3.02.4-1.8-2.10.00.9-1.01.0-1.4
Bone: post-yield work0.10.20.80.2-0.30.10.4-0.10.0-0.4-0.30.10.9-0.70.7-0.70.0
Bone: stiffness0.81.24.61.3-0.9-1.01.31.9-2.20.7-1.3-0.71.00.2-0.30.3-0.2
Bone: tissue strength1.31.32.51.2-1.2-1.11.61.2-1.30.6-1.4-0.91.5-0.90.8-0.8-0.8
Bone: trabecular number0.00.10.20.2-0.2-0.10.2-0.10.10.1-0.2-0.10.2-0.40.4-0.4-0.3
Bone: trabecular spacing1.31.65.20.6-1.0-0.31.3-0.30.1-0.5-0.9-0.22.3-2.12.0-2.1-0.6
Bone: trabecular thickness0.81.02.40.40.0-0.6-0.21.2-1.11.2-0.1-0.7-1.51.5-1.51.5-0.3
Bone: trabecular tissue density0.71.01.7-1.31.11.2-1.1-1.11.1-1.11.21.2-0.60.5-0.50.41.1
Breakpoint value in progressive ratio session0.50.61.90.20.1-0.4-0.10.9-0.90.70.0-0.4-0.61.3-1.41.40.1
Distance traveled before self-admin0.80.92.10.6-0.5-1.10.41.4-1.31.4-0.6-1.1-0.10.9-1.01.0-0.7
Distance traveled after self-admin0.91.01.80.9-1.2-0.91.00.1-0.10.6-0.9-1.00.9-1.31.3-1.3-1.3
Delta time in closed arm before/after self-admin0.10.10.3-0.0-0.00.20.1-0.40.4-0.50.00.30.3-0.50.5-0.60.1
Delta time in open arm before/after self-admin0.00.00.2-0.20.00.0-0.1-0.10.2-0.10.10.10.5-0.20.2-0.2-0.0
Diff in mean of infusions in LGA sessions0.50.50.9-0.90.80.7-0.9-0.80.8-0.51.00.6-0.40.6-0.60.60.7
Extinction: sum of active levers before priming2.32.33.6-1.91.91.5-1.9-0.90.9-1.11.71.6-1.01.6-1.61.61.7
Active lever presses in extinction session 62.01.95.0-1.21.40.9-1.30.1-0.1-0.41.30.9-1.42.2-2.22.21.5
Delta distance traveled before/after self-admin0.80.82.3-0.1-0.20.40.1-1.21.2-0.90.10.40.6-1.51.5-1.5-0.1
Delta ambulatory time before/after self-admin1.21.33.5-0.70.31.0-0.4-1.91.9-1.40.70.90.2-1.41.4-1.40.4
Time in closed arm before self-admin0.40.51.6-0.30.60.2-0.60.3-0.30.20.40.2-0.91.2-1.31.20.5
Time in closed arm after self-admin1.31.43.2-0.81.10.7-1.2-0.10.2-0.21.10.6-1.81.8-1.81.81.0
Time in open arm before self-admin0.20.20.5-0.40.10.4-0.0-0.70.6-0.60.10.40.4-0.70.7-0.70.2
Time in open arm after self-admin0.20.20.4-0.40.20.4-0.1-0.60.5-0.60.20.50.6-0.60.6-0.60.3
Sum of active levers in priming session hrs 5-60.60.61.30.6-0.4-0.80.31.1-1.11.1-0.4-0.8-0.50.9-0.90.9-0.5
Time to tail flick, vehicle, before self-admin0.20.20.30.3-0.4-0.30.40.1-0.20.3-0.4-0.30.6-0.60.6-0.5-0.5
Time to tail flick, vehicle, after self-admin1.81.93.2-1.71.61.7-1.4-1.51.5-1.71.51.8-0.80.4-0.40.41.7
Time to tail flick, test, before self-admin0.10.10.40.5-0.4-0.40.30.3-0.30.4-0.3-0.4-0.60.1-0.10.1-0.3
Time to tail flick, test, after self-admin0.50.50.8-0.80.80.8-0.7-0.60.6-0.70.80.8-0.60.5-0.60.50.9
Delta time to tail flick, vehicle, before/after SA0.40.40.8-0.50.30.7-0.2-0.90.9-0.90.40.70.1-0.60.6-0.60.5
Delta time to tail flick, test, before/after SA1.21.11.7-1.11.31.0-1.2-0.40.3-0.71.11.0-0.71.3-1.31.21.3
Ambulatory time before self-admin1.51.63.61.1-0.9-1.50.91.9-1.81.8-1.1-1.50.40.7-0.80.8-1.1
Ambulatory time after self-admin0.30.40.70.6-0.7-0.60.60.2-0.10.5-0.6-0.70.6-0.70.7-0.7-0.8
Total heroin consumption1.21.44.6-0.51.00.3-0.80.8-0.80.20.70.3-1.12.1-2.22.11.0
Area under the delay curve1.31.32.1-1.21.31.4-1.2-1.21.2-1.41.31.4-1.00.6-0.60.51.4
Delay disc. indifference point, 0s delay0.10.10.3-0.30.40.4-0.3-0.0-0.0-0.40.30.4-0.10.4-0.40.40.6
Delay disc. indifference point, 16s delay1.31.43.2-1.00.91.4-0.7-1.71.7-1.81.01.50.0-0.60.6-0.71.2
Delay disc. indifference point, 2s delay0.40.50.7-0.70.80.7-0.8-0.40.4-0.60.70.7-0.80.6-0.60.60.8
Delay disc. indifference point, 24s delay5.14.96.9-2.52.62.4-2.6-2.02.1-2.02.62.4-2.11.6-1.61.62.5
Delay disc. indifference point, 4s delay0.40.40.7-0.70.70.7-0.6-0.40.4-0.60.70.7-0.80.5-0.50.50.8
Delay disc. indifference point, 8s delay1.01.01.6-0.81.11.0-1.1-0.50.5-0.71.10.9-1.31.2-1.21.21.2
Delay discount exponential model param1.92.02.91.4-1.6-1.71.61.3-1.41.5-1.6-1.61.4-0.90.9-0.9-1.7
Delay discount hyperbolic model param1.81.92.91.4-1.6-1.61.51.3-1.31.5-1.6-1.61.3-0.90.9-0.8-1.7
Fecal boli incidents, locomotor time 10.40.51.0-0.80.60.8-0.6-1.01.0-0.90.70.8-0.1-0.30.3-0.30.6
Change in fecal boli incidents, locomotor task2.42.34.2-1.51.61.2-1.8-0.91.0-0.71.71.1-2.01.8-1.81.81.4
Time >=10cm from walls, locomotor time 11.71.73.31.4-1.4-0.91.40.2-0.30.4-1.2-0.91.7-1.81.8-1.8-1.3
Bouts of movement, locomotor time 11.51.72.9-1.71.51.5-1.6-1.31.3-1.31.51.5-1.00.8-0.70.71.4
Total resting periods, locomotor time 12.02.23.6-1.91.71.6-1.8-1.41.4-1.31.71.6-1.41.0-1.01.01.6
Rest time, locomotor task time 10.40.41.1-0.70.70.4-0.8-0.30.4-0.10.60.4-1.00.7-0.70.70.5
Distance moved, locomotor task time 10.40.50.90.9-0.8-0.61.00.5-0.50.3-0.7-0.60.9-0.60.5-0.6-0.5
Vertical activity count, locomotor time 11.11.22.91.2-1.2-0.91.30.6-0.70.4-1.1-0.81.7-1.21.1-1.2-0.9
Time >=10cm from walls, locomotor time 20.10.10.30.5-0.3-0.20.40.4-0.50.1-0.5-0.10.5-0.30.3-0.3-0.2
Bouts of movement, locomotor time 20.80.91.6-1.00.91.2-0.8-1.11.1-1.31.01.2-0.30.2-0.20.11.2
Total resting periods, locomotor time 20.60.61.4-0.70.61.0-0.5-1.11.0-1.20.71.00.1-0.30.3-0.40.9
Rest time, locomotor task time 20.10.10.4-0.30.10.1-0.2-0.60.7-0.10.20.1-0.1-0.30.3-0.3-0.1
Distance moved, locomotor task time 20.10.10.20.20.00.00.20.4-0.5-0.1-0.10.10.20.3-0.30.30.3
Vertical activity count, locomotor time 20.30.31.30.5-0.4-0.10.70.3-0.5-0.3-0.50.11.1-0.60.6-0.60.1
Weight adjusted by age1.61.73.61.3-1.3-1.61.21.9-1.91.7-1.4-1.60.80.1-0.10.1-1.3
Seeking ratio, delayed vs. immediate footshock1.51.72.61.6-1.5-1.51.61.3-1.41.2-1.5-1.51.2-0.80.8-0.8-1.4
Locomotion in novel chamber0.20.20.5-0.50.40.6-0.3-0.60.5-0.70.40.60.4-0.10.1-0.20.5
Locomotion in novel chamber post-restriction2.63.14.42.1-2.0-2.12.01.7-1.71.9-2.0-2.11.1-0.90.9-0.9-2.1
Progressive ratio0.40.50.8-0.90.80.8-0.8-0.70.7-0.80.80.8-0.50.4-0.40.30.8
Food seeking constrained by brief footshock0.30.40.7-0.60.60.4-0.8-0.30.4-0.00.70.3-0.90.8-0.80.80.4
Seeking ratio, punishment vs. effort0.20.20.40.5-0.5-0.50.50.3-0.30.5-0.5-0.60.3-0.40.4-0.4-0.6
Run reversals in cocaine runway, females0.40.40.9-0.40.20.6-0.3-1.00.9-0.80.30.60.4-0.80.8-0.80.2
Run reversals in cocaine runway, males0.90.92.40.8-0.7-1.20.41.3-1.21.5-0.7-1.2-0.30.7-0.70.7-1.0
Latency to leave start box in cocaine runway0.20.30.6-0.50.20.4-0.1-0.80.8-0.60.30.40.2-0.60.6-0.60.1
Latency to leave start box in cocaine runway, F0.70.71.8-0.50.00.50.1-1.11.0-0.90.10.61.0-1.31.3-1.40.1
Latency to leave start box in cocaine runway, M0.10.10.20.3-0.3-0.40.20.3-0.20.4-0.2-0.4-0.20.1-0.10.1-0.4
Cd content in liver1.21.42.4-1.31.31.5-1.2-1.21.1-1.51.31.6-0.40.4-0.40.41.5
Co content in liver0.20.20.5-0.60.40.5-0.4-0.70.7-0.50.50.5-0.1-0.10.1-0.10.3
Cu content in liver0.50.61.50.10.2-0.3-0.20.7-0.60.80.1-0.4-1.21.2-1.21.2-0.0
Fe content in liver0.91.02.2-1.21.01.2-1.0-1.41.5-1.21.21.2-0.3-0.00.0-0.11.0
K content in liver2.52.53.61.6-1.8-1.51.90.7-0.81.0-1.7-1.51.8-1.81.8-1.8-1.8
Mg content in liver1.71.85.00.7-1.1-0.41.2-0.50.4-0.3-0.9-0.42.0-2.22.2-2.2-0.9
Mn content in liver0.20.20.60.6-0.5-0.50.50.7-0.80.5-0.6-0.50.20.1-0.10.1-0.4
Na content in liver0.00.00.1-0.20.10.1-0.1-0.20.2-0.10.20.0-0.00.0-0.00.00.0
Rb content in liver1.41.82.71.5-1.5-1.21.61.0-1.10.8-1.6-1.11.7-1.41.4-1.4-1.3
Se content in liver0.50.61.10.7-0.9-0.70.70.2-0.10.6-0.7-0.80.6-0.90.9-0.9-1.1
Sr content in liver1.21.13.5-0.50.90.3-1.10.2-0.00.40.80.2-1.91.7-1.71.70.5
Zn content in liver0.00.00.1-0.20.10.2-0.1-0.20.3-0.20.20.1-0.40.0-0.00.00.1