Hub : Genes

Ogfod3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Adipose	gene expression	ENSRNOG00000036668	0.08	0.04	1.9e-09	0.07	0.07	0.08	0.07	8.5e-08	1.0e-08	6.7e-09	1.2e-08
2	Brain	mRNA stability	ENSRNOG00000036668	0.09	0.07	2.3e-05	0.06	0.05	0.05	0.05	3.4e-06	2.3e-05	4.2e-05	3.1e-05
3	Liver	gene expression	ENSRNOG00000036668	0.06	0.03	7.9e-08	0.07	0.06	0.05	0.05	5.2e-08	4.4e-07	2.0e-06	2.2e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
BMI with tail	0.1	0.4	0.9	0.2	-0.6	0.9
BMI without tail	3.0	6.2	17.8	4.2	-0.7	0.5
Body weight	1.3	5.6	6.5	2.6	-2.4	2.2
Epididymis fat weight	0.2	0.5	1.4	1.2	-0.1	0.0
Glucose	3.0	4.5	10.3	-3.2	-1.2	1.4
Heart weight	0.9	1.3	2.0	0.1	-1.3	1.4
Left kidney weight	0.2	0.6	0.8	-0.7	-0.9	0.7
Right kidney weight	0.1	0.2	0.7	-0.8	-0.1	0.2
Tail length	3.4	10.3	28.1	5.3	-1.5	0.7
Length with tail	0.8	3.0	4.5	2.1	-1.7	1.2
Length without tail	1.4	3.1	7.9	-2.8	-1.0	0.7
Liver weight, left	0.8	1.2	1.5	-1.0	-1.1	1.2
Liver weight, right	0.8	1.4	2.1	1.0	-1.1	1.4
Parametrial fat weight	1.2	2.4	4.1	2.0	-1.1	1.3
Retroperitoneal fat weight	2.4	7.8	15.9	4.0	-2.1	1.7
Intraocular pressure	0.7	0.9	2.7	1.6	-0.3	-0.2
Extensor digitorum longus weight	0.3	1.0	1.2	1.0	1.1	-0.9
Soleus weight	0.8	2.3	4.8	2.2	-1.0	1.1
Tibialis anterior weight	0.1	0.4	1.0	1.0	0.5	-0.1
Tibia length	6.3	17.7	27.4	2.2	-4.6	5.2
Number of licking bursts	0.2	0.2	0.3	0.6	0.4	-0.4
Food consumed during 24 hour testing period	0.4	0.5	1.3	1.1	-0.3	0.4
Times rat made contact with spout	3.3	3.7	5.2	1.6	-1.8	2.3
Mean time between licks in bursts	1.3	1.9	2.2	-1.3	1.3	-1.5
Mean num. licks in bursts	1.2	1.4	2.4	0.5	-1.3	1.6
Std. dev. time between licks in bursts	2.0	2.3	3.3	1.3	1.4	-1.8
Water consumed over 24 hours	0.3	0.4	0.9	-0.1	-0.5	0.9
Indifference point 0 sec	0.1	0.1	0.3	0.5	-0.1	-0.3
Indifference point AUC	0.1	0.1	0.4	0.6	0.0	0.0
Indifference point function ln k	1.4	2.0	2.5	-1.6	1.3	-1.3
Indifference point function log k	1.4	2.0	2.5	-1.6	1.3	-1.3
Delay discounting total patch changes 0 sec	0.1	0.2	0.3	0.5	0.1	-0.5
Delay discounting total patch changes 12 sec	0.2	0.2	0.4	0.6	-0.6	-0.1
Delay discounting total patch changes 18 sec	0.5	0.6	1.0	0.4	0.9	-1.0
Delay discounting total patch changes 24 sec	0.2	0.3	0.7	0.8	-0.4	0.1
Delay discounting total patch changes 6 sec	0.3	0.5	0.7	0.8	-0.7	0.5
Delay discounting time to switch 0 sec	0.2	0.3	0.4	-0.7	0.3	-0.7
Delay discounting water rate 0 sec	0.7	1.1	3.1	1.8	-0.4	-0.1
Delay discounting water rate 12 sec	0.2	0.3	0.6	0.0	0.5	-0.8
Delay discounting water rate 18 sec	0.3	0.5	0.7	0.6	0.6	-0.8
Delay discounting water rate 24 sec	0.4	0.6	1.7	1.3	0.2	-0.3
Delay discounting water rate 6 sec	0.2	0.3	0.4	-0.4	0.6	-0.6
Locomotor activity	0.6	0.9	1.8	-1.3	0.6	-0.8
Locomotor testing distance	1.3	2.1	2.3	-1.5	1.5	-1.4
Locomotor testing rearing	0.4	0.7	1.3	-0.3	0.8	-1.1
Light reinforcement 1	0.5	0.9	2.6	1.6	0.2	0.2
Light reinforcement 2	0.5	0.7	1.6	1.3	-0.4	0.6
Reaction time number correct	2.8	4.0	6.6	1.1	2.6	-2.1
Reaction time mean minus median	0.1	0.2	0.3	-0.4	-0.6	0.1
Reaction time mean minus median AUC	0.0	0.0	0.1	-0.2	-0.1	0.1
Reaction time num false alarms	0.0	0.0	0.1	-0.1	-0.0	0.4
Reaction time num false alarms AUC	0.1	0.1	0.2	-0.4	0.5	-0.2
Reaction time trials correct on left	2.8	4.0	6.6	1.1	2.6	-2.1
Reaction time trials on left	2.9	4.1	6.7	1.1	2.6	-2.1
Reaction time mean	0.3	0.4	0.7	0.8	-0.6	0.5
Reaction time mean AUC	0.2	0.2	0.7	0.8	-0.1	-0.1
Median of all reaction times	0.2	0.3	0.7	0.8	-0.4	0.4
Reaction time omissions	0.2	0.3	0.5	0.7	0.2	-0.6
Reaction time false alarm rate	0.6	0.8	1.0	-0.8	-0.9	1.0
Reaction time premature initiation rate	0.5	0.6	1.0	-0.7	1.0	-0.6
Reaction time premature initiations	1.9	2.8	5.0	-0.1	2.2	-1.8
Std. dev. reaction times	0.0	0.1	0.1	-0.3	0.2	-0.3
Reaction time trials completed	2.9	4.1	6.7	1.1	2.6	-2.1
Reaction time trials AUC	2.7	3.9	6.3	1.1	2.5	-2.0
Social response proportion	1.0	1.1	2.1	-0.7	0.8	-1.4
Social responses	0.8	1.0	1.8	-0.7	0.8	-1.3
Social time	0.3	0.4	0.7	-0.9	0.5	-0.4
Conditioned locomotion	2.2	2.6	7.0	2.7	-0.5	0.7
Cocaine response after cond. corrected	0.2	0.2	0.4	-0.7	-0.4	-0.1
Cocaine response after cond. not corrected	0.5	0.6	1.1	-1.0	0.2	-0.8
Cocaine response before conditioning	1.3	1.6	2.3	-0.8	1.5	-1.4
Saline control response	1.5	1.9	3.9	2.0	-1.0	0.9
Condit. Reinf. active minus inactive responses	0.4	0.5	0.6	0.8	-0.8	0.6
Condit. Reinf. active-inactive response ratio	2.0	2.1	2.8	1.1	-1.7	1.5
Condit. Reinf. active responses	0.1	0.1	0.4	0.6	-0.2	0.1
Condit. Reinf. inactive responses	0.5	0.6	0.9	-0.5	0.9	-0.7
Condit. Reinf. lever presses	0.2	0.3	0.5	0.7	0.4	-0.3
Condit. Reinf. lever reinforcers received	0.1	0.1	0.4	0.7	0.0	-0.0
Pavlov. Cond. lever latency	0.3	0.5	1.3	-1.1	-0.3	0.0
Pavlov. Cond. magazine entry latency	1.9	2.2	3.8	-0.8	2.0	-1.5
Pavlov. Cond. change in total contacts	0.4	0.5	0.9	0.0	0.9	-0.8
Pavlov. Cond. index score	0.4	0.6	1.1	0.1	1.1	-0.8
Pavlov. Cond. latency score	0.5	0.6	1.3	0.2	1.1	-0.8
Pavlov. Cond. lever contacts	0.6	0.8	2.2	1.5	0.4	0.0
Pavlov. Cond. magazine entry number	1.9	2.3	3.5	0.7	-1.9	1.7
Pavlov. Cond. intertrial magazine entries	1.1	1.4	2.7	1.6	-1.0	0.8
Pavlov. Cond. lever-magazine prob. diff.	0.5	0.7	1.3	0.0	1.1	-0.9
Pavlov. Cond. response bias	0.3	0.4	0.7	0.5	0.8	-0.6
Conditioned reinforcement - actives	0.6	0.6	1.1	0.3	1.1	-0.8
Conditioned reinforcement - inactives	0.5	0.6	0.8	0.9	-0.9	0.4
Conditioned locomotion	0.1	0.1	0.1	0.3	0.3	-0.3
Intermittent access intake day 1-15 change	0.8	0.8	2.1	1.4	-0.6	-0.2
Intermittent access intake escalation	0.9	0.9	2.5	1.6	-0.2	-0.3
Intermittent access intake escalation 2	2.3	2.2	3.1	1.1	-1.8	1.5
Intermitt. access day 1 inactive lever presses	0.3	0.3	0.5	0.6	-0.7	0.3
Intermitt. access day 15 inactive lever presses	0.5	0.5	1.4	1.2	-0.4	-0.0
Intermitt. access escalation Index	1.1	0.9	2.3	1.5	0.6	-0.3
Intermittent access day 1 total infusions	0.2	0.2	0.7	0.8	-0.2	-0.0
Intermittent access day 15 total infusions	0.8	0.8	2.4	1.6	-0.1	-0.3
Intermittent access terminal intake (last 3 days)	1.0	1.1	2.8	1.7	-0.7	0.3
Intermittent access total infusions	0.5	0.6	1.5	1.2	0.1	-0.5
Intermittent access day 1 locomotion	0.6	0.6	1.1	0.4	0.7	-1.0
Intermittent access day 15 total locomotion	0.4	0.4	0.9	1.0	-0.5	-0.3
Intermittent access total locomotion	0.3	0.4	0.5	0.7	0.2	-0.7
Intermittent access standard deviation	0.8	0.9	1.7	-1.3	-0.9	-0.0
Cocaine induced anxiety	5.4	6.2	12.3	0.4	-3.5	2.5
Post-drug Anxiety	1.2	1.3	3.2	-0.4	-1.8	0.8
Baseline Anxiety	5.6	5.9	8.4	-1.9	2.9	-2.4
Lifetime Intake	0.2	0.3	0.6	0.8	0.2	-0.3
Incentive Sensitization - Responses	0.7	0.7	1.2	0.9	0.0	1.1
Incentive Sensitization - Breakpoint	0.6	0.6	1.1	0.8	-0.0	1.0
Progressive ratio test 1 active lever presses	0.8	0.8	2.1	1.4	-0.2	-0.5
Progressive ratio test 1 breakpoint	0.9	0.9	2.6	1.6	-0.3	-0.2
Progressive ratio test 1 inactive lever presses	0.9	1.0	2.6	1.6	-0.6	0.2
Progressive ratio test 2 active lever presses	0.4	0.4	1.0	1.0	-0.1	0.4
Progressive ratio test 2 breakpoint	0.4	0.5	1.4	1.2	0.1	0.1
Progressive ratio test 2 inactive lever presses	0.2	0.2	0.4	0.5	-0.6	0.3
Total sessions with >9 infusions	0.4	0.4	0.8	-0.1	0.9	-0.7
Short access day 1 total inactive lever presses	0.7	0.8	1.4	0.1	1.0	-1.2
Short access day 10 total inactive lever presses	1.6	1.7	2.7	1.3	-1.6	0.9
Short access day 1 total infusions	0.8	0.8	1.7	-1.3	0.8	-0.3
Short access day 10 total infusions	0.5	0.5	1.3	1.1	-0.6	0.2
Short access total infusions	0.1	0.1	0.1	0.4	0.1	0.3
Short access day 1 locomotion	0.4	0.4	0.8	-0.9	-0.4	0.5
Short access day 10 total locomotion	0.3	0.4	0.5	-0.7	-0.5	-0.5
Short access total locomotion	0.2	0.2	0.6	-0.8	-0.0	-0.2
Compulsive drug intake	0.2	0.2	0.3	0.2	-0.5	0.4
One hour access (0.3 mA shock)	0.9	1.0	2.7	1.6	-0.5	0.3
One hour access (shock baseline)	0.5	0.6	1.2	1.1	0.6	-0.2
Number of responses in last shaping day	0.4	0.4	0.9	0.5	-0.3	1.0
Context. condit. distance diff. score	1.1	1.3	2.6	1.6	0.7	-0.9
Locomotion velocity, session 1	0.9	1.0	2.7	-1.7	-0.4	0.3
Locomotion distance, session 1	2.5	3.3	4.8	-1.4	2.2	-1.7
Locomotion velocity, session 2	3.0	3.6	6.0	-2.5	1.5	-1.5
Locomotion distance, session 2	0.8	1.2	1.9	-0.3	1.4	-1.3
Locomotion velocity, session 3	1.1	1.2	3.2	-1.8	0.5	-0.4
Locomotion distance, session 3	2.6	2.9	4.3	-2.1	1.4	-1.6
Stereotopy head waving bouts, day 3	0.4	0.4	1.1	-1.1	-0.2	0.3
Stereotopy head waving duration, day 3	0.2	0.2	0.6	-0.8	0.0	0.1
Locomotion velocity, session 7	1.1	1.2	1.5	-0.8	1.2	-1.2
Locomotion distance, session 7	3.4	4.3	6.0	-1.1	2.5	-2.4
Stereotopy head waving bouts, day 7	0.1	0.1	0.2	0.1	-0.4	0.2
Stereotopy head waving duration, day 7	0.2	0.2	0.5	0.3	-0.7	0.3
Locomotion velocity, session 8	1.0	1.2	1.8	-0.4	1.3	-1.3
Locomotion distance, session 8	1.9	2.9	3.5	1.3	1.8	-1.9
Degree of sensitization distance	0.6	0.6	1.8	1.4	0.1	0.1
Degree of sensitization stereotypy	0.2	0.2	0.3	0.5	-0.5	0.2
Condit. Reinf. active minus inactive responses	1.4	1.6	2.7	1.7	-0.8	1.2
Condit. Reinf. active-inactive response ratio	0.4	0.4	0.6	0.7	-0.4	0.8
Condit. Reinf. active responses	2.7	3.3	6.9	2.6	-1.1	1.3
Condit. Reinf. inactive responses	1.2	1.4	3.5	1.9	-0.7	0.5
Incentive salience index mean	1.0	1.2	3.0	1.7	-0.4	0.7
Condit. Reinf. lever presses	0.5	0.7	1.0	0.6	1.0	-0.8
Time in familiar zone, hab. session 1	0.3	0.3	0.6	-0.3	-0.8	0.4
Time in novel zone, hab. session 1	0.1	0.1	0.2	0.2	0.4	-0.4
Total zone transitions, hab. session 1	0.2	0.3	0.4	-0.6	0.6	-0.3
Total locomotion distance, hab. session 1	0.0	0.1	0.1	0.3	0.3	-0.0
Locomotion velocity, hab. session 1	0.1	0.1	0.2	0.4	0.4	-0.0
Time in familiar zone, hab. session 2	0.2	0.2	0.7	0.1	0.2	-0.8
Time in novel zone, hab. session 2	0.1	0.1	0.3	-0.6	0.3	0.0
Total zone transitions, hab. session 2	1.0	1.3	2.7	0.3	1.6	-1.1
Total locomotion distance, hab. session 2	0.9	1.2	1.5	1.2	1.1	-1.0
Locomotion velocity, hab. session 2	0.8	1.1	1.9	1.4	0.9	-0.8
Novel to familiar place preference ratio	2.8	2.9	4.4	0.8	-2.1	1.9
Novelty place preference	2.8	2.9	4.5	0.7	-2.1	1.9
Time in novel zone, NPP test	2.2	2.3	3.5	0.6	-1.9	1.7
Total zone transitions, NPP test	2.3	3.3	5.7	0.3	2.4	-2.1
Total locomotion distance, NPP test	1.9	2.6	3.7	1.0	1.9	-1.7
Locomotion velocity, NPP test	1.2	1.7	2.2	1.1	1.5	-1.3
Pavlov. Cond. lever latency	1.5	1.9	3.4	-0.4	1.5	-1.8
Pavlov. Cond. magazine entry latency	2.6	3.4	4.5	1.1	-2.1	2.1
Pavlov. Cond. change in total contacts	1.0	1.1	1.8	-0.2	-1.2	1.4
Pavlov. Cond. index score	2.8	3.6	4.6	1.5	-2.0	2.1
Pavlov. Cond. latency score	2.6	3.3	4.7	1.2	-2.0	2.2
Pavlov. Cond. lever contacts	0.7	0.8	1.2	0.6	-0.9	1.1
Pavlov. Cond. magazine entry number	3.5	4.4	6.4	-0.8	2.5	-2.5
Pavlov. Cond. intertrial magazine entries	0.4	0.5	1.1	1.0	0.4	-0.4
Pavlov. Cond. lever-magazine prob. diff.	2.8	3.5	4.6	1.4	-2.0	2.1
Pavlov. Cond. response bias	2.3	2.9	4.2	0.8	-2.0	2.0
Bone: apparent density	0.1	0.1	0.2	0.5	0.3	0.1
Bone surface	0.2	0.4	0.9	0.9	-0.2	0.6
Bone volume	0.2	0.3	0.7	0.9	-0.1	0.5
Bone: connectivity density	0.3	0.5	0.9	0.5	1.0	-0.6
Bone: cortical apparent density	1.2	1.6	3.2	-1.8	0.8	-1.0
Bone: cortical area	2.7	4.1	5.7	1.0	-2.3	2.4
Bone: cortical porosity	2.9	3.2	4.7	-0.6	-2.2	2.1
Bone: cortical porosity	2.7	2.9	4.4	-0.1	-2.0	2.1
Bone: cortical thickness	3.5	5.8	8.8	0.2	-3.0	2.9
Bone: cortical thickness	1.2	1.4	2.1	-0.3	-1.4	1.4
Bone: cortical tissue density	1.3	1.7	3.4	-1.8	0.8	-1.0
Bone: elastic displacement	1.6	1.8	3.2	0.6	-1.4	1.8
Bone: elastic work	7.6	9.9	16.1	1.1	-3.5	4.0
Bone: endosteal estimation	0.4	0.8	1.0	0.8	1.0	-0.9
Bone: endosteal perimeter	0.4	0.8	1.5	1.2	-0.6	0.8
Bone: final force	2.4	3.9	5.8	1.0	-2.2	2.4
Bone: final moment	3.1	5.1	7.5	1.2	-2.5	2.7
Bone: marrow area	0.4	0.8	1.0	0.8	1.0	-0.9
Bone: maximum diameter	0.4	0.7	0.8	0.7	-0.8	0.9
Bone: maximum force	2.2	3.9	5.2	1.3	-2.2	2.3
Bone: maximum moment	2.9	5.1	6.7	1.5	-2.5	2.6
Bone: minimum diameter	1.4	2.6	2.9	1.6	-1.7	1.5
Bone: periosteal estimation	0.6	1.1	1.4	1.2	-1.0	1.0
Bone: periosteal perimeter	2.4	4.0	5.7	0.8	-2.4	2.4
Bone: post-yield work	0.3	0.4	0.8	0.0	0.6	-0.9
Bone: stiffness	0.1	0.2	0.3	-0.3	-0.5	0.4
Bone: tissue strength	0.3	0.3	0.7	0.8	-0.1	0.2
Bone: trabecular number	0.0	0.1	0.1	0.3	0.2	0.2
Bone: trabecular spacing	1.4	1.8	2.5	0.9	1.5	-1.6
Bone: trabecular thickness	1.8	2.2	3.7	-0.2	-1.7	1.9
Bone: trabecular tissue density	0.6	0.9	1.5	-1.2	0.8	-0.8
Breakpoint value in progressive ratio session	0.6	0.6	1.4	-0.5	-1.2	0.4
Distance traveled before self-admin	2.4	2.5	4.4	0.3	-1.7	2.1
Distance traveled after self-admin	0.7	0.8	2.4	1.6	-0.0	-0.2
Delta time in closed arm before/after self-admin	0.8	0.8	1.6	0.0	1.3	-0.9
Delta time in open arm before/after self-admin	0.1	0.1	0.2	0.0	-0.4	-0.2
Diff in mean of infusions in LGA sessions	0.5	0.5	1.3	-1.1	0.1	-0.5
Extinction: sum of active levers before priming	1.7	1.8	4.3	-2.1	-0.5	0.8
Active lever presses in extinction session 6	1.2	1.2	3.1	-1.8	-0.7	0.0
Delta distance traveled before/after self-admin	2.1	2.2	4.2	0.5	1.5	-2.1
Delta ambulatory time before/after self-admin	3.3	3.6	7.0	0.2	1.9	-2.6
Time in closed arm before self-admin	0.4	0.4	0.6	-0.7	-0.8	0.4
Time in closed arm after self-admin	0.4	0.5	1.3	-1.2	-0.1	-0.2
Time in open arm before self-admin	0.2	0.3	0.5	-0.1	0.7	-0.5
Time in open arm after self-admin	0.0	0.0	0.0	-0.1	0.1	-0.2
Sum of active levers in priming session hrs 5-6	0.9	0.9	1.8	0.3	-1.4	0.9
Time to tail flick, vehicle, before self-admin	0.4	0.4	0.5	0.7	-0.6	0.6
Time to tail flick, vehicle, after self-admin	1.9	2.0	3.4	-1.8	1.3	-1.0
Time to tail flick, test, before self-admin	0.5	0.5	1.3	0.5	-0.1	-1.1
Time to tail flick, test, after self-admin	0.9	0.9	1.9	-0.7	0.5	-1.4
Delta time to tail flick, vehicle, before/after SA	1.4	1.3	2.2	-0.6	1.5	-1.2
Delta time to tail flick, test, before/after SA	0.8	0.7	2.1	-1.5	-0.1	0.2
Ambulatory time before self-admin	3.2	3.3	5.3	0.7	-2.0	2.3
Ambulatory time after self-admin	0.4	0.4	1.0	1.0	-0.3	-0.0
Total heroin consumption	1.5	1.9	2.5	-1.6	-1.5	0.9
Area under the delay curve	1.8	1.9	2.7	-1.4	1.1	-1.6
Delay disc. indifference point, 0s delay	0.2	0.2	0.6	-0.8	-0.0	-0.2
Delay disc. indifference point, 16s delay	3.6	3.6	6.2	-0.8	2.0	-2.5
Delay disc. indifference point, 2s delay	0.4	0.4	0.8	-0.9	0.3	-0.6
Delay disc. indifference point, 24s delay	2.6	2.5	5.4	-2.3	0.9	-1.2
Delay disc. indifference point, 4s delay	0.8	0.8	1.4	-1.2	0.2	-1.0
Delay disc. indifference point, 8s delay	0.8	0.8	1.6	-1.3	0.2	-0.9
Delay discount exponential model param	2.0	2.1	2.9	1.7	-1.0	1.6
Delay discount hyperbolic model param	2.0	2.1	2.9	1.7	-1.0	1.6
Fecal boli incidents, locomotor time 1	0.2	0.2	0.4	-0.2	0.6	-0.5
Change in fecal boli incidents, locomotor task	1.0	0.9	2.2	-1.5	-0.5	-0.6
Time >=10cm from walls, locomotor time 1	1.3	1.3	3.3	1.8	0.1	-0.7
Bouts of movement, locomotor time 1	1.0	1.1	3.0	-1.7	0.5	-0.1
Total resting periods, locomotor time 1	1.1	1.2	3.3	-1.8	0.5	-0.0
Rest time, locomotor task time 1	0.3	0.3	0.6	-0.6	-0.2	0.8
Distance moved, locomotor task time 1	0.7	0.8	2.1	0.5	0.2	-1.4
Vertical activity count, locomotor time 1	0.5	0.6	1.2	0.7	-0.0	-1.1
Time >=10cm from walls, locomotor time 2	0.3	0.3	0.6	0.5	-0.7	0.2
Bouts of movement, locomotor time 2	1.6	1.7	2.0	-1.3	1.4	-1.2
Total resting periods, locomotor time 2	1.6	1.7	2.7	-0.9	1.6	-1.3
Rest time, locomotor task time 2	0.3	0.3	1.0	-0.0	1.0	-0.1
Distance moved, locomotor task time 2	0.4	0.4	0.9	-0.4	-0.5	-0.9
Vertical activity count, locomotor time 2	0.2	0.2	0.7	-0.1	-0.2	-0.8
Weight adjusted by age	3.4	3.8	5.3	1.0	-2.3	2.2
Seeking ratio, delayed vs. immediate footshock	1.0	1.1	1.3	1.2	-1.0	1.0
Locomotion in novel chamber	0.5	0.7	1.0	-0.3	0.9	-1.0
Locomotion in novel chamber post-restriction	2.0	2.3	5.2	2.3	-1.2	0.6
Progressive ratio	0.2	0.2	0.4	-0.7	0.1	-0.3
Food seeking constrained by brief footshock	0.2	0.2	0.3	-0.3	-0.5	0.5
Seeking ratio, punishment vs. effort	0.1	0.2	0.4	0.6	0.1	0.3
Run reversals in cocaine runway, females	0.6	0.6	1.2	-0.1	1.1	-0.8
Run reversals in cocaine runway, males	2.0	2.0	3.2	0.6	-1.8	1.5
Latency to leave start box in cocaine runway	0.5	0.5	1.5	-0.1	1.2	-0.3
Latency to leave start box in cocaine runway, F	0.8	0.9	2.2	-0.0	1.5	-0.6
Latency to leave start box in cocaine runway, M	0.0	0.0	0.1	0.3	0.2	0.1
Cd content in liver	1.3	1.4	1.8	-1.3	0.9	-1.3
Co content in liver	0.2	0.3	0.4	-0.1	0.6	-0.6
Cu content in liver	0.7	0.9	1.4	-0.1	-1.1	1.2
Fe content in liver	0.6	0.8	1.3	-0.6	0.8	-1.1
K content in liver	1.4	1.4	3.8	2.0	0.4	-0.3
Mg content in liver	2.0	2.1	2.4	1.4	1.5	-1.4
Mn content in liver	0.0	0.1	0.1	0.2	-0.3	0.2
Na content in liver	0.1	0.1	0.2	-0.2	0.5	-0.0
Rb content in liver	0.5	0.6	1.7	1.3	-0.2	0.2
Se content in liver	0.4	0.4	1.3	1.1	-0.0	-0.1
Sr content in liver	1.4	1.3	2.2	-0.6	-1.5	1.1
Zn content in liver	0.1	0.1	0.2	0.1	0.2	-0.5