# | tissue | modality | RNA phenotype | h2 | h2 se | h2 P | eQTL R2 | BLUP R2 | ENET R2 | LASSO R2 | eQTL P | BLUP P | ENET P | LASSO P |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Adipose | gene expression | ENSRNOG00000064417 | 0.0950 | 0.0610 | 2.5e-09 | 0.047 | 0.067 | 0.088 | 0.084 | 5.9e-06 | 6.8e-08 | 5.3e-10 | 1.2e-09 |
2 | Adipose | isoform ratio | ENSRNOT00000105061 | 0.0810 | 0.0610 | 8.6e-06 | 0.027 | 0.026 | 0.030 | 0.024 | 4.7e-04 | 6.4e-04 | 2.6e-04 | 1.1e-03 |
3 | Adipose | isoform ratio | ENSRNOT00000115448 | 0.0580 | 0.0420 | 1.7e-04 | 0.014 | 0.015 | 0.011 | 0.011 | 1.0e-02 | 6.7e-03 | 2.0e-02 | 2.0e-02 |
4 | Adipose | intron excision ratio | chr1:154518241:154571292 | 0.0441 | 0.0353 | 2.6e-03 | 0.016 | 0.009 | 0.011 | 0.011 | 6.6e-03 | 2.7e-02 | 2.0e-02 | 1.9e-02 |
5 | BLA | gene expression | ENSRNOG00000064417 | 0.0728 | 0.0548 | 1.3e-03 | 0.039 | 0.037 | 0.032 | 0.029 | 3.8e-03 | 4.3e-03 | 8.1e-03 | 1.1e-02 |
6 | BLA | isoform ratio | ENSRNOT00000105061 | 0.2900 | 0.1600 | 6.5e-09 | 0.157 | 0.153 | 0.147 | 0.160 | 9.1e-09 | 1.5e-08 | 2.9e-08 | 6.7e-09 |
7 | BLA | isoform ratio | ENSRNOT00000115448 | 0.2900 | 0.1300 | 4.1e-11 | 0.186 | 0.182 | 0.186 | 0.187 | 3.1e-10 | 4.9e-10 | 3.2e-10 | 2.8e-10 |
8 | BLA | intron excision ratio | chr1:154518241:154520221 | 0.2600 | 0.1800 | 4.2e-07 | 0.094 | 0.085 | 0.066 | 0.086 | 9.9e-06 | 2.6e-05 | 2.1e-04 | 2.3e-05 |
9 | BLA | intron excision ratio | chr1:154518241:154571292 | 0.1500 | 0.0970 | 3.3e-05 | 0.081 | 0.066 | 0.070 | 0.082 | 4.1e-05 | 2.0e-04 | 1.3e-04 | 3.5e-05 |
10 | BLA | intron excision ratio | chr1:154520399:154523006 | 0.1800 | 0.1100 | 4.8e-06 | 0.102 | 0.076 | 0.091 | 0.082 | 4.4e-06 | 6.7e-05 | 1.4e-05 | 3.6e-05 |
11 | Brain | gene expression | ENSRNOG00000064417 | 0.0980 | 0.0650 | 1.3e-08 | 0.095 | 0.095 | 0.095 | 0.093 | 3.9e-09 | 4.3e-09 | 4.2e-09 | 6.1e-09 |
12 | Brain | isoform ratio | ENSRNOT00000105061 | 0.3284 | 0.1746 | 0.0e+00 | 0.214 | 0.219 | 0.218 | 0.219 | 1.4e-19 | 4.3e-20 | 5.5e-20 | 4.3e-20 |
13 | Brain | isoform ratio | ENSRNOT00000115448 | 0.4092 | 0.1702 | 0.0e+00 | 0.297 | 0.311 | 0.309 | 0.312 | 8.3e-28 | 2.4e-29 | 4.2e-29 | 2.1e-29 |
14 | Brain | intron excision ratio | chr1:154518241:154520221 | 0.2465 | 0.1353 | 5.0e-16 | 0.166 | 0.171 | 0.163 | 0.165 | 3.2e-15 | 1.3e-15 | 5.9e-15 | 4.0e-15 |
15 | Brain | intron excision ratio | chr1:154518241:154537228 | 0.1032 | 0.0703 | 3.0e-06 | 0.070 | 0.064 | 0.068 | 0.070 | 4.5e-07 | 1.5e-06 | 6.2e-07 | 4.3e-07 |
16 | Brain | intron excision ratio | chr1:154518241:154571292 | 0.1390 | 0.0893 | 1.1e-08 | 0.092 | 0.094 | 0.090 | 0.088 | 7.2e-09 | 5.1e-09 | 9.9e-09 | 1.6e-08 |
17 | Brain | intron excision ratio | chr1:154520399:154523006 | 0.2235 | 0.1275 | 1.5e-14 | 0.156 | 0.154 | 0.146 | 0.152 | 2.7e-14 | 3.6e-14 | 1.8e-13 | 5.5e-14 |
18 | IL | isoform ratio | ENSRNOT00000105061 | 0.2700 | 0.1590 | 2.8e-03 | 0.113 | 0.057 | 0.053 | 0.072 | 1.2e-03 | 1.7e-02 | 2.2e-02 | 8.5e-03 |
19 | IL | isoform ratio | ENSRNOT00000115448 | 0.3020 | 0.1640 | 5.9e-04 | 0.119 | 0.097 | 0.102 | 0.110 | 8.9e-04 | 2.5e-03 | 2.0e-03 | 1.3e-03 |
20 | LHb | gene expression | ENSRNOG00000064417 | 0.4544 | 0.1850 | 2.2e-07 | 0.111 | 0.134 | 0.141 | 0.148 | 1.4e-03 | 4.5e-04 | 3.2e-04 | 2.3e-04 |
21 | LHb | isoform ratio | ENSRNOT00000115448 | 0.1977 | 0.1368 | 3.1e-03 | 0.051 | 0.082 | 0.085 | 0.058 | 2.4e-02 | 5.6e-03 | 4.9e-03 | 1.7e-02 |
22 | Liver | gene expression | ENSRNOG00000064417 | 0.0560 | 0.0360 | 1.3e-05 | 0.022 | 0.027 | 0.028 | 0.026 | 1.6e-03 | 4.5e-04 | 3.9e-04 | 6.7e-04 |
23 | NAcc | gene expression | ENSRNOG00000064417 | 0.1300 | 0.0810 | 6.6e-10 | 0.137 | 0.129 | 0.136 | 0.135 | 2.2e-10 | 8.1e-10 | 2.7e-10 | 3.2e-10 |
24 | NAcc | isoform ratio | ENSRNOT00000105061 | 0.1452 | 0.0893 | 4.2e-08 | 0.107 | 0.111 | 0.104 | 0.104 | 2.3e-08 | 1.3e-08 | 3.8e-08 | 4.0e-08 |
25 | NAcc | isoform ratio | ENSRNOT00000115448 | 0.1727 | 0.1041 | 1.1e-09 | 0.126 | 0.131 | 0.136 | 0.130 | 1.2e-09 | 5.4e-10 | 2.5e-10 | 6.4e-10 |
26 | NAcc | intron excision ratio | chr1:154518241:154520221 | 0.0680 | 0.0511 | 1.7e-03 | 0.046 | 0.045 | 0.043 | 0.045 | 2.3e-04 | 2.6e-04 | 3.8e-04 | 2.9e-04 |
27 | NAcc | intron excision ratio | chr1:154520399:154523006 | 0.1106 | 0.0722 | 3.9e-06 | 0.082 | 0.080 | 0.071 | 0.072 | 1.0e-06 | 1.4e-06 | 5.9e-06 | 4.8e-06 |
28 | OFC | gene expression | ENSRNOG00000064417 | 0.1566 | 0.1104 | 3.4e-03 | 0.083 | 0.087 | 0.066 | 0.062 | 5.3e-03 | 4.4e-03 | 1.2e-02 | 1.4e-02 |
29 | OFC | isoform ratio | ENSRNOT00000105061 | 0.4700 | 0.1800 | 2.8e-07 | 0.278 | 0.286 | 0.132 | 0.262 | 2.5e-07 | 1.6e-07 | 5.0e-04 | 6.2e-07 |
30 | OFC | isoform ratio | ENSRNOT00000115448 | 0.4500 | 0.1800 | 3.2e-07 | 0.283 | 0.298 | 0.137 | 0.266 | 2.0e-07 | 8.4e-08 | 3.9e-04 | 4.9e-07 |
31 | OFC | intron excision ratio | chr1:154518241:154520221 | 0.2844 | 0.1657 | 1.0e-04 | 0.082 | 0.140 | 0.142 | 0.156 | 5.4e-03 | 3.4e-04 | 3.1e-04 | 1.6e-04 |
32 | OFC | intron excision ratio | chr1:154518241:154571292 | 0.2827 | 0.1693 | 7.6e-04 | 0.131 | 0.120 | 0.093 | 0.118 | 5.4e-04 | 9.0e-04 | 3.3e-03 | 1.0e-03 |
33 | PL | isoform ratio | ENSRNOT00000105061 | 0.3100 | 0.1400 | 0.0e+00 | 0.232 | 0.205 | 0.231 | 0.230 | 1.4e-17 | 1.7e-15 | 1.7e-17 | 1.8e-17 |
34 | PL | isoform ratio | ENSRNOT00000115448 | 0.4600 | 0.1500 | 0.0e+00 | 0.357 | 0.308 | 0.359 | 0.362 | 2.9e-28 | 7.5e-24 | 1.9e-28 | 1.1e-28 |
35 | PL | intron excision ratio | chr1:154518241:154520221 | 0.4009 | 0.1799 | 0.0e+00 | 0.262 | 0.226 | 0.256 | 0.259 | 5.6e-20 | 4.2e-17 | 1.5e-19 | 1.0e-19 |
36 | PL | intron excision ratio | chr1:154518241:154571292 | 0.0999 | 0.0779 | 4.2e-05 | 0.053 | 0.055 | 0.058 | 0.053 | 6.8e-05 | 5.5e-05 | 3.3e-05 | 7.3e-05 |
37 | PL | intron excision ratio | chr1:154520399:154523006 | 0.1770 | 0.1140 | 1.2e-08 | 0.114 | 0.101 | 0.105 | 0.110 | 5.4e-09 | 4.0e-08 | 2.3e-08 | 1.1e-08 |
All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, the gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method.
Trait | Avg chi2 ratio | Avg chi2 | Max chi2 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 | 35 | 36 | 37 |
---|
Trait | Avg chi2 ratio | Avg chi2 | Max chi2 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 | 35 | 36 | 37 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Run reversals in cocaine runway, females | 6.3 | 6.2 | 8.1 | -1.8 | 1.9 | -2.8 | 2.6 | -2.4 | 2.4 | -2.6 | -2.4 | 2.6 | -2.4 | -2.3 | 2.7 | -2.8 | -2.7 | 2.6 | 2.7 | -2.4 | 2.5 | -2.4 | -1.7 | -2.7 | -2.7 | -2.2 | 2.8 | -2.8 | -2.4 | -2.4 | -2.8 | 2.4 | -2.4 | -2.8 | 2.4 | 2.4 | -2.5 | -2.4 | 2.7 | -2.4 |
Tail length | 5.8 | 17.7 | 26.5 | -0.2 | 5.1 | -4.4 | 4.7 | -1.5 | 4.7 | -4.7 | -4.7 | 4.7 | -4.8 | -1.6 | 4.7 | -4.6 | -4.5 | 4.7 | 4.5 | -4.7 | 4.9 | -4.5 | 0.1 | -4.5 | -0.3 | -1.5 | 4.4 | -4.2 | -4.8 | -4.8 | -3.6 | 4.8 | -4.8 | -3.9 | 4.7 | 4.8 | -4.7 | -4.8 | 2.6 | -4.8 |
Condit. Reinf. lever presses | 5.7 | 7.8 | 22.3 | 4.6 | 4.7 | -1.2 | 2.7 | 3.4 | 2.9 | -2.7 | -2.9 | 2.7 | -2.8 | 3.4 | 2.5 | -1.8 | -1.4 | 2.7 | 1.5 | -2.6 | 2.8 | -2.5 | 4.6 | -1.5 | 4.1 | 3.3 | 1.0 | -0.4 | -2.9 | -2.9 | 0.6 | 3.0 | -2.8 | -0.0 | 2.8 | 2.9 | -2.7 | -2.9 | -2.3 | -2.9 |
Mean time between licks in bursts | 5.4 | 7.5 | 13.1 | 1.4 | 3.6 | -2.6 | 3.3 | 0.3 | 3.2 | -3.2 | -3.2 | 3.3 | -3.2 | 0.3 | 3.2 | -2.9 | -2.7 | 3.3 | 2.7 | -3.2 | 3.2 | -3.3 | 1.5 | -2.6 | 0.3 | 0.3 | 2.5 | -2.2 | -3.2 | -3.2 | -1.6 | 3.3 | -3.2 | -1.9 | 3.2 | 3.2 | -3.2 | -3.2 | 0.6 | -3.2 |
Pavlov. Cond. lever contacts | 5.3 | 7.4 | 24.6 | 5.0 | 4.6 | -0.9 | 2.4 | 3.7 | 2.6 | -2.4 | -2.6 | 2.4 | -2.6 | 3.7 | 2.2 | -1.5 | -1.1 | 2.4 | 1.2 | -2.3 | 2.6 | -2.3 | 4.9 | -1.2 | 4.5 | 3.7 | 0.7 | -0.0 | -2.6 | -2.6 | 1.0 | 2.8 | -2.5 | 0.3 | 2.6 | 2.6 | -2.4 | -2.6 | -2.7 | -2.6 |
Retroperitoneal fat weight | 5.2 | 17.2 | 32.9 | -5.0 | 1.3 | -4.6 | 3.5 | -5.3 | 3.4 | -3.5 | -3.4 | 3.5 | -3.5 | -5.3 | 3.7 | -4.2 | -4.5 | 3.5 | 4.4 | -3.6 | 3.3 | -3.5 | -4.7 | -4.5 | -5.2 | -5.3 | 4.7 | -5.2 | -3.4 | -3.4 | -5.4 | 3.2 | -3.4 | -5.1 | 3.4 | 3.4 | -3.5 | -3.4 | 5.7 | -3.4 |
Condit. Reinf. active responses | 5.1 | 7.1 | 16.3 | 2.8 | 4.0 | -2.0 | 3.0 | 1.6 | 3.1 | -3.0 | -3.1 | 3.0 | -3.1 | 1.6 | 2.9 | -2.4 | -2.2 | 3.0 | 2.2 | -2.9 | 3.1 | -2.8 | 2.9 | -2.2 | 2.1 | 1.6 | 1.9 | -1.5 | -3.1 | -3.1 | -0.6 | 3.2 | -3.1 | -1.2 | 3.1 | 3.1 | -3.0 | -3.1 | -0.6 | -3.1 |
Pavlov. Cond. lever latency | 5.1 | 7.0 | 23.3 | -4.8 | -4.4 | 0.9 | -2.4 | -3.6 | -2.5 | 2.4 | 2.5 | -2.4 | 2.5 | -3.6 | -2.2 | 1.5 | 1.1 | -2.4 | -1.1 | 2.2 | -2.5 | 2.2 | -4.8 | 1.1 | -4.3 | -3.6 | -0.7 | -0.0 | 2.5 | 2.5 | -1.0 | -2.7 | 2.5 | -0.3 | -2.5 | -2.5 | 2.4 | 2.5 | 2.6 | 2.5 |
Condit. Reinf. lever reinforcers received | 5.0 | 7.1 | 17.5 | 3.1 | 4.2 | -1.9 | 2.9 | 1.9 | 3.1 | -3.0 | -3.1 | 2.9 | -3.1 | 1.9 | 2.8 | -2.3 | -2.0 | 2.9 | 2.1 | -2.9 | 3.0 | -2.8 | 3.2 | -2.1 | 2.5 | 1.9 | 1.7 | -1.2 | -3.1 | -3.1 | -0.4 | 3.2 | -3.0 | -0.9 | 3.1 | 3.1 | -2.9 | -3.1 | -0.9 | -3.1 |
Pavlov. Cond. response bias | 5.0 | 6.9 | 25.9 | 5.1 | 4.4 | -0.7 | 2.2 | 3.8 | 2.3 | -2.2 | -2.4 | 2.2 | -2.3 | 3.9 | 2.0 | -1.2 | -0.9 | 2.2 | 0.9 | -2.1 | 2.4 | -2.1 | 5.1 | -0.9 | 4.7 | 3.9 | 0.5 | 0.2 | -2.4 | -2.4 | 1.2 | 2.6 | -2.3 | 0.6 | 2.3 | 2.4 | -2.2 | -2.4 | -2.9 | -2.4 |
Delta time in closed arm before/after self-admin | 4.0 | 3.9 | 8.2 | -2.2 | 0.7 | -2.2 | 1.7 | -2.7 | 1.7 | -1.7 | -1.7 | 1.7 | -1.7 | -2.4 | 1.7 | -2.0 | -2.2 | 1.7 | 2.2 | -1.8 | 1.6 | -1.8 | -2.0 | -2.1 | -2.0 | -2.4 | 2.3 | -2.3 | -1.7 | -1.7 | -2.5 | 1.6 | -1.7 | -2.4 | 1.7 | 1.7 | -1.7 | -1.7 | 2.9 | -1.7 |
Std. dev. time between licks in bursts | 3.9 | 4.6 | 6.3 | 0.0 | 2.3 | -2.2 | 2.4 | -0.5 | 2.4 | -2.4 | -2.4 | 2.4 | -2.5 | -0.7 | 2.4 | -2.3 | -2.3 | 2.4 | 2.3 | -2.5 | 2.4 | -2.5 | 0.1 | -2.2 | -1.1 | -0.7 | 2.2 | -2.2 | -2.4 | -2.4 | -1.8 | 2.4 | -2.4 | -2.0 | 2.4 | 2.4 | -2.4 | -2.4 | 1.3 | -2.4 |
Time in closed arm before self-admin | 3.8 | 4.4 | 11.8 | 2.5 | -0.9 | 2.3 | -1.8 | 2.7 | -1.6 | 1.8 | 1.6 | -1.8 | 1.6 | 2.7 | -1.9 | 2.2 | 2.2 | -1.8 | -2.2 | 1.7 | -1.7 | 1.7 | 2.4 | 2.1 | 3.4 | 2.8 | -2.3 | 2.4 | 1.6 | 1.6 | 2.7 | -1.6 | 1.7 | 2.5 | -1.6 | -1.6 | 1.7 | 1.6 | -3.0 | 1.6 |
Pavlov. Cond. index score | 3.7 | 4.8 | 18.3 | 4.3 | 3.7 | -0.5 | 1.8 | 3.2 | 1.9 | -1.8 | -1.9 | 1.8 | -1.9 | 3.3 | 1.6 | -1.0 | -0.7 | 1.8 | 0.8 | -1.7 | 1.9 | -1.7 | 4.2 | -0.7 | 3.8 | 3.2 | 0.4 | 0.2 | -1.9 | -1.9 | 1.1 | 2.1 | -1.9 | 0.5 | 1.9 | 1.9 | -1.8 | -1.9 | -2.4 | -1.9 |
Pavlov. Cond. lever-magazine prob. diff. | 3.6 | 4.7 | 16.4 | 4.1 | 3.7 | -0.7 | 1.9 | 3.0 | 2.0 | -1.9 | -2.0 | 1.9 | -2.0 | 3.1 | 1.7 | -1.1 | -0.8 | 1.9 | 0.9 | -1.8 | 2.0 | -1.8 | 4.0 | -0.8 | 3.6 | 3.0 | 0.5 | 0.1 | -2.0 | -2.0 | 0.9 | 2.2 | -2.0 | 0.3 | 2.0 | 2.0 | -1.9 | -2.0 | -2.2 | -2.0 |
Liver weight, right | 3.5 | 5.8 | 10.0 | -2.6 | 1.5 | -2.6 | 2.1 | -2.9 | 2.2 | -2.1 | -2.2 | 2.1 | -2.2 | -2.9 | 2.1 | -2.4 | -2.6 | 2.1 | 2.6 | -2.2 | 2.2 | -2.1 | -2.4 | -2.6 | -2.7 | -2.8 | 2.7 | -3.0 | -2.2 | -2.2 | -3.0 | 2.0 | -2.1 | -2.9 | 2.1 | 2.2 | -2.1 | -2.2 | 3.2 | -2.2 |
Condit. Reinf. active minus inactive responses | 3.5 | 4.3 | 10.7 | 2.5 | 3.3 | -1.4 | 2.3 | 1.6 | 2.4 | -2.3 | -2.4 | 2.3 | -2.4 | 1.6 | 2.2 | -1.8 | -1.6 | 2.3 | 1.6 | -2.2 | 2.3 | -2.1 | 2.5 | -1.6 | 1.9 | 1.5 | 1.3 | -0.9 | -2.4 | -2.4 | -0.3 | 2.5 | -2.3 | -0.7 | 2.4 | 2.4 | -2.3 | -2.4 | -0.8 | -2.4 |
Condit. Reinf. inactive responses | 3.5 | 4.4 | 8.8 | 1.8 | 3.0 | -1.7 | 2.4 | 0.9 | 2.5 | -2.4 | -2.5 | 2.4 | -2.5 | 0.9 | 2.4 | -2.0 | -1.8 | 2.4 | 1.9 | -2.4 | 2.5 | -2.3 | 1.9 | -1.9 | 1.1 | 0.9 | 1.6 | -1.3 | -2.5 | -2.5 | -0.8 | 2.5 | -2.4 | -1.1 | 2.5 | 2.5 | -2.4 | -2.5 | -0.1 | -2.5 |
Pavlov. Cond. change in total contacts | 3.5 | 4.8 | 20.1 | 4.5 | 3.7 | -0.4 | 1.7 | 3.5 | 1.8 | -1.7 | -1.8 | 1.7 | -1.8 | 3.5 | 1.5 | -0.8 | -0.5 | 1.7 | 0.6 | -1.6 | 1.8 | -1.6 | 4.4 | -0.6 | 4.1 | 3.5 | 0.2 | 0.4 | -1.8 | -1.8 | 1.3 | 2.0 | -1.8 | 0.7 | 1.8 | 1.8 | -1.7 | -1.8 | -2.7 | -1.8 |
Length with tail | 3.4 | 12.5 | 16.2 | -0.8 | 4.0 | -3.8 | 3.8 | -1.8 | 3.9 | -3.8 | -3.9 | 3.8 | -3.9 | -1.8 | 3.8 | -3.8 | -3.8 | 3.8 | 3.9 | -3.9 | 4.0 | -3.8 | -0.5 | -3.9 | -0.5 | -1.7 | 3.8 | -3.8 | -3.9 | -3.9 | -3.3 | 3.9 | -3.9 | -3.5 | 3.9 | 3.9 | -3.9 | -3.9 | 2.6 | -3.9 |
Reaction time premature initiation rate | 3.4 | 4.6 | 6.7 | 0.1 | 1.8 | -2.2 | 2.5 | -0.6 | 2.5 | -2.5 | -2.5 | 2.5 | -2.4 | -0.5 | 2.5 | -2.4 | -2.3 | 2.5 | 2.3 | -2.6 | 2.4 | -2.6 | 0.2 | -2.3 | -0.9 | -0.5 | 2.2 | -2.1 | -2.5 | -2.5 | -1.7 | 2.5 | -2.5 | -1.9 | 2.4 | 2.5 | -2.5 | -2.5 | 1.2 | -2.5 |
Pavlov. Cond. latency score | 3.2 | 4.0 | 16.2 | 4.0 | 3.3 | -0.4 | 1.6 | 3.1 | 1.7 | -1.6 | -1.7 | 1.6 | -1.7 | 3.1 | 1.4 | -0.9 | -0.6 | 1.6 | 0.6 | -1.5 | 1.7 | -1.4 | 4.0 | -0.6 | 3.7 | 3.1 | 0.3 | 0.3 | -1.7 | -1.7 | 1.1 | 1.9 | -1.7 | 0.6 | 1.7 | 1.7 | -1.6 | -1.7 | -2.4 | -1.7 |
Ambulatory time after self-admin | 3.2 | 3.5 | 5.6 | 0.7 | -2.1 | 2.0 | -2.4 | 1.3 | -1.9 | 2.3 | 1.8 | -2.4 | 1.7 | 1.2 | -2.4 | 2.3 | 2.0 | -2.4 | -2.0 | 2.0 | -1.9 | 2.0 | 0.5 | 1.9 | 1.7 | 1.1 | -2.0 | 1.6 | 1.8 | 1.8 | 1.8 | -2.0 | 2.0 | 1.8 | -1.8 | -1.8 | 2.3 | 1.8 | -1.7 | 1.8 |
Degree of sensitization distance | 3.1 | 3.1 | 4.6 | -1.6 | 1.3 | -1.9 | 1.7 | -1.9 | 1.7 | -1.7 | -1.7 | 1.7 | -1.6 | -1.8 | 1.7 | -1.9 | -1.9 | 1.7 | 1.9 | -1.7 | 1.7 | -1.7 | -1.5 | -2.0 | -1.7 | -1.9 | 2.0 | -2.2 | -1.7 | -1.7 | -2.1 | 1.5 | -1.6 | -2.0 | 1.7 | 1.7 | -1.6 | -1.7 | 2.1 | -1.7 |
Active lever presses in extinction session 6 | 3.0 | 2.9 | 8.2 | 2.3 | -0.4 | 1.9 | -1.1 | 2.9 | -1.3 | 1.1 | 1.3 | -1.1 | 1.5 | 2.5 | -1.2 | 1.5 | 1.8 | -1.1 | -1.8 | 1.2 | -1.5 | 1.2 | 2.2 | 1.9 | 1.4 | 2.3 | -1.9 | 2.3 | 1.3 | 1.3 | 2.3 | -1.2 | 1.3 | 2.2 | -1.4 | -1.3 | 1.2 | 1.3 | -2.6 | 1.3 |
BMI without tail | 2.7 | 5.7 | 7.1 | -0.6 | 1.9 | -2.6 | 2.6 | -1.3 | 2.7 | -2.6 | -2.7 | 2.6 | -2.6 | -1.4 | 2.7 | -2.6 | -2.6 | 2.6 | 2.6 | -2.6 | 2.6 | -2.6 | -0.5 | -2.6 | -0.4 | -1.2 | 2.6 | -2.6 | -2.7 | -2.7 | -2.3 | 2.6 | -2.7 | -2.4 | 2.7 | 2.7 | -2.6 | -2.7 | 1.9 | -2.7 |
Bone: tissue strength | 2.5 | 2.4 | 3.1 | 0.5 | -1.5 | 1.7 | -1.6 | 0.8 | -1.7 | 1.6 | 1.8 | -1.6 | 1.8 | 0.8 | -1.6 | 1.6 | 1.7 | -1.6 | -1.7 | 1.8 | -1.7 | 1.8 | 0.3 | 1.7 | 0.7 | 0.8 | -1.7 | 1.8 | 1.8 | 1.8 | 1.5 | -1.7 | 1.7 | 1.6 | -1.7 | -1.8 | 1.7 | 1.8 | -1.2 | 1.8 |
Bone: minimum diameter | 2.3 | 4.3 | 5.5 | -0.4 | 2.1 | -2.2 | 2.3 | -0.9 | 2.3 | -2.3 | -2.3 | 2.3 | -2.3 | -1.0 | 2.3 | -2.2 | -2.2 | 2.3 | 2.2 | -2.3 | 2.3 | -2.3 | -0.3 | -2.3 | -1.1 | -1.0 | 2.2 | -2.2 | -2.3 | -2.3 | -1.9 | 2.3 | -2.3 | -2.0 | 2.3 | 2.3 | -2.3 | -2.3 | 1.5 | -2.3 |
Latency to leave start box in cocaine runway, F | 2.3 | 2.5 | 6.3 | -2.3 | 0.7 | -1.7 | 1.3 | -2.5 | 1.1 | -1.2 | -1.1 | 1.3 | -1.0 | -2.4 | 1.3 | -1.6 | -1.6 | 1.3 | 1.6 | -1.0 | 1.1 | -1.0 | -2.3 | -1.5 | -2.3 | -2.5 | 1.7 | -1.9 | -1.1 | -1.1 | -2.1 | 1.0 | -1.1 | -1.9 | 1.0 | 1.1 | -1.2 | -1.1 | 2.4 | -1.1 |
Bone: trabecular tissue density | 2.2 | 3.1 | 6.1 | -2.1 | 0.6 | -1.9 | 1.5 | -2.4 | 1.4 | -1.5 | -1.4 | 1.5 | -1.6 | -2.3 | 1.6 | -1.8 | -1.9 | 1.5 | 1.9 | -1.5 | 1.5 | -1.6 | -2.0 | -1.9 | -1.9 | -2.3 | 2.0 | -2.2 | -1.4 | -1.4 | -2.3 | 1.3 | -1.4 | -2.2 | 1.4 | 1.4 | -1.5 | -1.4 | 2.5 | -1.4 |
Locomotion velocity, hab. session 2 | 2.1 | 2.8 | 3.8 | -1.0 | 1.5 | -1.8 | 1.8 | -1.3 | 1.8 | -1.8 | -1.7 | 1.8 | -1.8 | -1.2 | 1.8 | -1.9 | -1.8 | 1.8 | 1.8 | -1.7 | 1.7 | -1.7 | -0.9 | -1.8 | -1.3 | -1.3 | 1.8 | -1.9 | -1.7 | -1.7 | -1.8 | 1.7 | -1.7 | -1.8 | 1.7 | 1.7 | -1.8 | -1.7 | 1.6 | -1.7 |
Distance traveled after self-admin | 2.1 | 2.3 | 3.7 | 0.2 | -1.7 | 1.6 | -1.9 | 0.9 | -1.6 | 1.9 | 1.6 | -1.9 | 1.4 | 0.6 | -1.9 | 1.9 | 1.6 | -1.9 | -1.6 | 1.7 | -1.6 | 1.7 | 0.1 | 1.5 | 0.6 | 0.5 | -1.5 | 1.3 | 1.6 | 1.6 | 1.3 | -1.7 | 1.6 | 1.4 | -1.6 | -1.6 | 1.8 | 1.6 | -1.1 | 1.6 |
Seeking ratio, punishment vs. effort | 2.1 | 2.5 | 3.6 | -0.0 | 1.6 | -1.7 | 1.7 | -0.5 | 1.9 | -1.7 | -1.9 | 1.7 | -1.9 | -0.7 | 1.7 | -1.6 | -1.7 | 1.7 | 1.7 | -1.8 | 1.9 | -1.8 | 0.1 | -1.7 | 0.3 | -0.5 | 1.7 | -1.6 | -1.9 | -1.9 | -1.4 | 1.8 | -1.8 | -1.4 | 1.9 | 1.9 | -1.8 | -1.9 | 1.0 | -1.9 |
Soleus weight | 2.0 | 5.9 | 8.1 | -1.6 | 1.6 | -2.7 | 2.4 | -2.0 | 2.5 | -2.4 | -2.5 | 2.4 | -2.5 | -2.1 | 2.5 | -2.6 | -2.7 | 2.4 | 2.7 | -2.5 | 2.4 | -2.5 | -1.4 | -2.7 | -2.0 | -2.0 | 2.7 | -2.8 | -2.5 | -2.5 | -2.7 | 2.4 | -2.4 | -2.7 | 2.5 | 2.5 | -2.4 | -2.5 | 2.5 | -2.5 |
Time in open arm after self-admin | 2.0 | 2.2 | 7.5 | -0.3 | 1.8 | -1.5 | 1.9 | -0.5 | 1.4 | -1.8 | -1.4 | 1.9 | -1.3 | -0.7 | 1.9 | -1.8 | -1.5 | 1.9 | 1.5 | -1.6 | 1.5 | -1.6 | -0.2 | -1.4 | -2.7 | -0.9 | 1.5 | -1.3 | -1.4 | -1.4 | -1.3 | 1.6 | -1.5 | -1.3 | 1.4 | 1.4 | -1.7 | -1.4 | 1.1 | -1.4 |
Time to tail flick, test, after self-admin | 2.0 | 2.0 | 4.2 | -0.2 | 2.0 | -1.5 | 1.5 | -0.7 | 1.6 | -1.5 | -1.6 | 1.5 | -1.5 | -0.6 | 1.5 | -1.5 | -1.5 | 1.5 | 1.5 | -1.5 | 1.7 | -1.5 | -0.2 | -1.5 | 0.3 | -0.8 | 1.5 | -1.5 | -1.6 | -1.6 | -1.3 | 1.6 | -1.6 | -1.4 | 1.6 | 1.6 | -1.5 | -1.6 | 1.0 | -1.6 |
Body weight | 1.9 | 7.9 | 10.0 | -1.0 | 1.4 | -3.1 | 3.0 | -1.8 | 3.1 | -3.1 | -3.1 | 3.0 | -3.1 | -1.8 | 3.1 | -3.1 | -3.1 | 3.0 | 3.1 | -3.1 | 2.8 | -3.1 | -0.9 | -3.1 | -0.3 | -1.7 | 3.1 | -3.2 | -3.1 | -3.1 | -2.8 | 3.0 | -3.1 | -2.9 | 3.1 | 3.1 | -3.0 | -3.1 | 2.4 | -3.1 |
Left kidney weight | 1.9 | 5.3 | 8.5 | 0.2 | 2.0 | -2.4 | 2.7 | -0.6 | 2.7 | -2.7 | -2.7 | 2.7 | -2.6 | -0.6 | 2.6 | -2.5 | -2.4 | 2.7 | 2.5 | -2.9 | 2.5 | -2.9 | 0.4 | -2.4 | -0.4 | -0.6 | 2.4 | -2.2 | -2.6 | -2.6 | -1.8 | 2.7 | -2.7 | -2.1 | 2.6 | 2.6 | -2.7 | -2.6 | 1.3 | -2.6 |
Conditioned locomotion | 1.9 | 2.3 | 9.8 | 2.5 | -0.5 | 1.5 | -1.2 | 2.7 | -0.8 | 1.1 | 0.8 | -1.2 | 0.7 | 2.4 | -1.3 | 1.6 | 1.4 | -1.2 | -1.4 | 0.8 | -0.8 | 0.6 | 2.4 | 1.4 | 3.1 | 2.4 | -1.5 | 1.5 | 0.8 | 0.8 | 2.0 | -0.7 | 0.8 | 1.9 | -0.8 | -0.8 | 1.1 | 0.8 | -2.4 | 0.8 |
Mn content in liver | 1.8 | 2.1 | 3.7 | -0.6 | -1.9 | 1.4 | -1.7 | -0.1 | -1.7 | 1.7 | 1.7 | -1.7 | 1.7 | -0.1 | -1.7 | 1.5 | 1.4 | -1.7 | -1.4 | 1.7 | -1.8 | 1.6 | -0.7 | 1.4 | -0.4 | -0.1 | -1.3 | 1.2 | 1.7 | 1.7 | 0.9 | -1.7 | 1.7 | 1.0 | -1.7 | -1.7 | 1.7 | 1.7 | -0.3 | 1.7 |
Epididymis fat weight | 1.7 | 4.0 | 6.1 | -1.9 | 0.3 | -2.2 | 2.0 | -2.2 | 1.8 | -2.0 | -1.8 | 2.0 | -1.7 | -2.2 | 2.1 | -2.2 | -2.1 | 2.0 | 2.1 | -2.1 | 1.4 | -2.0 | -1.7 | -2.1 | -2.1 | -2.1 | 2.2 | -2.4 | -1.8 | -1.8 | -2.4 | 1.7 | -1.8 | -2.3 | 1.8 | 1.8 | -1.9 | -1.8 | 2.5 | -1.8 |
Liver weight, left | 1.7 | 2.7 | 4.4 | -1.7 | 0.7 | -1.8 | 1.6 | -1.9 | 1.5 | -1.6 | -1.5 | 1.6 | -1.5 | -1.8 | 1.6 | -1.8 | -1.8 | 1.6 | 1.8 | -1.5 | 1.4 | -1.4 | -1.6 | -1.8 | -2.0 | -1.9 | 1.8 | -2.1 | -1.5 | -1.5 | -2.0 | 1.4 | -1.4 | -2.0 | 1.5 | 1.5 | -1.5 | -1.5 | 2.1 | -1.5 |
Indifference point function ln k | 1.7 | 2.3 | 4.8 | 2.0 | -0.8 | 1.7 | -1.1 | 2.1 | -1.2 | 1.2 | 1.3 | -1.1 | 1.2 | 2.1 | -1.2 | 1.4 | 1.6 | -1.1 | -1.6 | 1.3 | -1.3 | 1.1 | 1.9 | 1.6 | 1.9 | 2.1 | -1.7 | 2.0 | 1.3 | 1.3 | 2.0 | -1.1 | 1.2 | 1.9 | -1.2 | -1.3 | 1.2 | 1.3 | -2.2 | 1.3 |
Indifference point function log k | 1.7 | 2.3 | 4.8 | 2.0 | -0.8 | 1.7 | -1.1 | 2.1 | -1.2 | 1.2 | 1.3 | -1.1 | 1.2 | 2.1 | -1.2 | 1.4 | 1.6 | -1.1 | -1.6 | 1.3 | -1.3 | 1.1 | 1.9 | 1.6 | 1.9 | 2.1 | -1.7 | 2.0 | 1.3 | 1.3 | 2.0 | -1.1 | 1.2 | 1.9 | -1.2 | -1.3 | 1.2 | 1.3 | -2.2 | 1.3 |
Reaction time trials on left | 1.7 | 2.3 | 4.0 | 0.9 | -0.6 | 1.7 | -1.5 | 1.3 | -1.6 | 1.5 | 1.6 | -1.5 | 1.8 | 1.2 | -1.5 | 1.6 | 1.7 | -1.5 | -1.7 | 1.8 | -1.4 | 1.7 | 0.9 | 1.7 | 1.1 | 1.1 | -1.7 | 2.0 | 1.6 | 1.6 | 1.7 | -1.6 | 1.6 | 1.7 | -1.6 | -1.6 | 1.5 | 1.6 | -1.5 | 1.6 |
Reaction time trials completed | 1.7 | 2.3 | 4.0 | 0.9 | -0.6 | 1.7 | -1.5 | 1.3 | -1.6 | 1.5 | 1.6 | -1.5 | 1.8 | 1.2 | -1.5 | 1.6 | 1.7 | -1.5 | -1.7 | 1.8 | -1.4 | 1.7 | 0.9 | 1.7 | 1.1 | 1.1 | -1.7 | 2.0 | 1.6 | 1.6 | 1.7 | -1.6 | 1.6 | 1.7 | -1.6 | -1.6 | 1.5 | 1.6 | -1.5 | 1.6 |
Pavlov. Cond. magazine entry number | 1.7 | 2.1 | 11.5 | -3.4 | -2.0 | -0.4 | -0.5 | -2.8 | -0.6 | 0.5 | 0.6 | -0.5 | 0.6 | -2.9 | -0.4 | -0.1 | -0.3 | -0.5 | 0.3 | 0.5 | -0.6 | 0.4 | -3.3 | -0.3 | -3.2 | -2.8 | 0.5 | -1.0 | 0.6 | 0.6 | -1.5 | -0.8 | 0.6 | -1.1 | -0.6 | -0.6 | 0.5 | 0.6 | 2.4 | 0.6 |
Pavlov. Cond. intertrial magazine entries | 1.7 | 2.2 | 2.9 | -0.8 | 1.1 | -1.6 | 1.6 | -1.1 | 1.6 | -1.6 | -1.6 | 1.6 | -1.5 | -1.1 | 1.6 | -1.6 | -1.6 | 1.6 | 1.6 | -1.6 | 1.6 | -1.7 | -0.7 | -1.6 | -1.3 | -1.1 | 1.6 | -1.7 | -1.6 | -1.6 | -1.6 | 1.5 | -1.6 | -1.6 | 1.6 | 1.6 | -1.5 | -1.6 | 1.4 | -1.6 |
Total locomotion distance, hab. session 2 | 1.7 | 2.3 | 2.9 | -0.7 | 1.4 | -1.6 | 1.6 | -1.1 | 1.6 | -1.6 | -1.6 | 1.6 | -1.6 | -1.0 | 1.6 | -1.7 | -1.6 | 1.6 | 1.6 | -1.6 | 1.6 | -1.6 | -0.6 | -1.6 | -1.0 | -1.1 | 1.6 | -1.7 | -1.6 | -1.6 | -1.5 | 1.5 | -1.6 | -1.6 | 1.6 | 1.6 | -1.6 | -1.6 | 1.4 | -1.6 |
Bone: elastic work | 1.7 | 2.3 | 4.1 | -1.0 | -2.0 | 1.3 | -1.8 | -0.6 | -1.8 | 1.8 | 1.8 | -1.8 | 1.8 | -0.4 | -1.7 | 1.5 | 1.4 | -1.8 | -1.4 | 1.8 | -1.8 | 1.7 | -1.1 | 1.4 | -0.3 | -0.4 | -1.3 | 1.2 | 1.8 | 1.8 | 0.7 | -1.8 | 1.8 | 0.9 | -1.8 | -1.8 | 1.8 | 1.8 | -0.0 | 1.8 |
Delta ambulatory time before/after self-admin | 1.7 | 1.9 | 5.3 | 1.9 | -0.1 | 1.5 | -1.3 | 2.1 | -0.9 | 1.2 | 0.9 | -1.3 | 0.8 | 2.0 | -1.3 | 1.4 | 1.4 | -1.3 | -1.4 | 1.1 | -0.8 | 1.1 | 1.6 | 1.3 | 2.0 | 2.0 | -1.6 | 1.3 | 0.9 | 0.9 | 1.8 | -0.9 | 1.0 | 1.7 | -0.8 | -0.9 | 1.2 | 0.9 | -2.3 | 0.9 |
Delay discounting total patch changes 12 sec | 1.6 | 2.2 | 4.6 | 0.5 | 2.1 | -1.4 | 1.7 | -0.0 | 1.7 | -1.7 | -1.7 | 1.7 | -1.9 | -0.1 | 1.6 | -1.5 | -1.5 | 1.7 | 1.5 | -1.7 | 1.7 | -1.6 | 0.6 | -1.5 | 0.5 | -0.0 | 1.4 | -1.2 | -1.7 | -1.7 | -0.9 | 1.8 | -1.7 | -1.1 | 1.7 | 1.7 | -1.7 | -1.7 | 0.5 | -1.7 |
Reaction time number correct | 1.6 | 2.3 | 3.9 | 0.9 | -0.5 | 1.7 | -1.5 | 1.3 | -1.6 | 1.5 | 1.6 | -1.5 | 1.8 | 1.2 | -1.5 | 1.6 | 1.7 | -1.5 | -1.7 | 1.8 | -1.3 | 1.7 | 0.9 | 1.6 | 1.2 | 1.1 | -1.7 | 2.0 | 1.6 | 1.6 | 1.7 | -1.5 | 1.6 | 1.7 | -1.6 | -1.6 | 1.5 | 1.6 | -1.5 | 1.6 |
Reaction time trials correct on left | 1.6 | 2.3 | 3.9 | 0.9 | -0.5 | 1.7 | -1.5 | 1.3 | -1.6 | 1.5 | 1.6 | -1.5 | 1.8 | 1.2 | -1.5 | 1.6 | 1.7 | -1.5 | -1.7 | 1.8 | -1.3 | 1.7 | 0.9 | 1.6 | 1.2 | 1.1 | -1.7 | 2.0 | 1.6 | 1.6 | 1.7 | -1.5 | 1.6 | 1.7 | -1.6 | -1.6 | 1.5 | 1.6 | -1.5 | 1.6 |
Degree of sensitization stereotypy | 1.6 | 1.7 | 9.0 | 3.0 | 1.1 | 0.8 | -0.0 | 2.7 | -0.0 | 0.0 | 0.0 | -0.0 | -0.0 | 2.6 | -0.1 | 0.5 | 0.7 | -0.0 | -0.7 | 0.0 | -0.0 | 0.0 | 2.9 | 0.8 | 2.7 | 2.6 | -0.9 | 1.3 | 0.0 | 0.0 | 1.7 | 0.2 | -0.0 | 1.4 | -0.0 | -0.0 | 0.0 | 0.0 | -2.4 | 0.0 |
Bone: endosteal estimation | 1.6 | 3.5 | 5.9 | 0.7 | 2.4 | -1.8 | 2.2 | 0.1 | 2.2 | -2.2 | -2.2 | 2.2 | -2.2 | 0.1 | 2.2 | -2.0 | -1.8 | 2.2 | 1.8 | -2.2 | 2.2 | -2.2 | 0.8 | -1.9 | 0.0 | 0.1 | 1.7 | -1.6 | -2.2 | -2.2 | -1.1 | 2.2 | -2.2 | -1.4 | 2.2 | 2.2 | -2.2 | -2.2 | 0.5 | -2.2 |
Bone: endosteal perimeter | 1.6 | 3.2 | 5.3 | 1.1 | 2.3 | -1.6 | 2.2 | 0.5 | 2.1 | -2.2 | -2.1 | 2.2 | -2.1 | 0.4 | 2.1 | -1.9 | -1.7 | 2.2 | 1.7 | -2.1 | 2.1 | -2.1 | 1.2 | -1.7 | 0.3 | 0.4 | 1.5 | -1.4 | -2.1 | -2.1 | -0.9 | 2.2 | -2.1 | -1.2 | 2.1 | 2.1 | -2.1 | -2.1 | 0.1 | -2.1 |
Bone: marrow area | 1.6 | 3.4 | 5.3 | 0.5 | 2.3 | -1.8 | 2.1 | -0.0 | 2.2 | -2.1 | -2.2 | 2.1 | -2.1 | -0.0 | 2.1 | -2.0 | -1.8 | 2.1 | 1.8 | -2.1 | 2.1 | -2.1 | 0.6 | -1.9 | -0.1 | -0.0 | 1.7 | -1.6 | -2.2 | -2.2 | -1.2 | 2.2 | -2.1 | -1.4 | 2.2 | 2.2 | -2.1 | -2.2 | 0.6 | -2.2 |
Delay disc. indifference point, 4s delay | 1.6 | 1.6 | 2.6 | 0.1 | 1.6 | -1.3 | 1.4 | -0.3 | 1.5 | -1.4 | -1.5 | 1.4 | -1.4 | -0.3 | 1.4 | -1.3 | -1.4 | 1.4 | 1.4 | -1.6 | 1.4 | -1.5 | 0.2 | -1.3 | -0.3 | -0.3 | 1.3 | -1.1 | -1.5 | -1.5 | -1.0 | 1.5 | -1.5 | -1.2 | 1.4 | 1.5 | -1.5 | -1.5 | 0.8 | -1.5 |
Std. dev. reaction times | 1.5 | 2.0 | 2.7 | -0.4 | 1.0 | -1.5 | 1.6 | -0.8 | 1.5 | -1.6 | -1.5 | 1.6 | -1.6 | -0.9 | 1.6 | -1.6 | -1.6 | 1.6 | 1.6 | -1.6 | 1.6 | -1.6 | -0.3 | -1.5 | -1.4 | -0.8 | 1.5 | -1.5 | -1.5 | -1.5 | -1.4 | 1.6 | -1.6 | -1.5 | 1.5 | 1.5 | -1.5 | -1.5 | 1.1 | -1.5 |
Social responses | 1.5 | 1.9 | 3.5 | -1.3 | 1.0 | -1.6 | 1.2 | -1.6 | 1.3 | -1.2 | -1.3 | 1.2 | -1.4 | -1.4 | 1.2 | -1.4 | -1.6 | 1.2 | 1.5 | -1.4 | 1.5 | -1.3 | -1.2 | -1.6 | -1.0 | -1.4 | 1.6 | -1.9 | -1.3 | -1.3 | -1.7 | 1.3 | -1.3 | -1.7 | 1.3 | 1.3 | -1.1 | -1.3 | 1.7 | -1.3 |
Total locomotion distance, hab. session 1 | 1.5 | 2.2 | 3.9 | -1.6 | 0.9 | -1.6 | 1.2 | -1.8 | 1.3 | -1.3 | -1.3 | 1.2 | -1.4 | -1.8 | 1.3 | -1.5 | -1.6 | 1.2 | 1.6 | -1.3 | 1.4 | -1.3 | -1.5 | -1.6 | -1.7 | -1.9 | 1.7 | -1.9 | -1.3 | -1.3 | -1.9 | 1.2 | -1.3 | -1.8 | 1.3 | 1.3 | -1.3 | -1.3 | 2.0 | -1.3 |
Time in open arm before self-admin | 1.5 | 1.6 | 12.0 | -2.8 | -0.5 | -0.9 | 0.3 | -2.3 | -0.1 | -0.2 | 0.1 | 0.3 | 0.1 | -2.5 | 0.4 | -0.7 | -0.8 | 0.3 | 0.7 | -0.1 | -0.0 | -0.2 | -2.6 | -0.6 | -3.5 | -2.6 | 1.0 | -1.0 | 0.1 | 0.1 | -1.6 | -0.0 | -0.1 | -1.2 | -0.2 | -0.1 | -0.3 | 0.1 | 2.5 | 0.1 |
Distance moved, locomotor task time 2 | 1.5 | 1.7 | 5.4 | 1.7 | 2.3 | -0.9 | 1.5 | 1.2 | 1.4 | -1.5 | -1.5 | 1.5 | -1.5 | 1.0 | 1.4 | -1.1 | -1.0 | 1.5 | 1.0 | -1.5 | 1.5 | -1.6 | 1.7 | -1.0 | 0.8 | 1.0 | 0.8 | -0.5 | -1.4 | -1.4 | -0.1 | 1.6 | -1.5 | -0.4 | 1.5 | 1.4 | -1.6 | -1.4 | -0.6 | -1.4 |
Co content in liver | 1.5 | 1.7 | 3.2 | 0.8 | 1.8 | -1.2 | 1.5 | 0.2 | 1.5 | -1.5 | -1.5 | 1.5 | -1.5 | 0.3 | 1.5 | -1.4 | -1.2 | 1.5 | 1.2 | -1.5 | 1.5 | -1.6 | 0.8 | -1.2 | 0.6 | 0.3 | 1.1 | -1.0 | -1.5 | -1.5 | -0.7 | 1.6 | -1.5 | -0.9 | 1.5 | 1.5 | -1.5 | -1.5 | 0.2 | -1.5 |
Cu content in liver | 1.5 | 1.9 | 2.7 | 0.3 | 1.6 | -1.4 | 1.6 | -0.1 | 1.6 | -1.6 | -1.6 | 1.6 | -1.6 | -0.2 | 1.6 | -1.5 | -1.4 | 1.6 | 1.4 | -1.5 | 1.6 | -1.5 | 0.4 | -1.4 | -0.1 | -0.2 | 1.3 | -1.3 | -1.6 | -1.6 | -1.0 | 1.6 | -1.6 | -1.1 | 1.6 | 1.6 | -1.6 | -1.6 | 0.6 | -1.6 |
Number of licking bursts | 1.4 | 1.7 | 10.4 | -2.9 | -1.3 | -0.8 | -0.1 | -2.5 | -0.1 | 0.1 | 0.1 | -0.1 | 0.1 | -2.6 | 0.0 | -0.4 | -0.7 | -0.1 | 0.6 | -0.1 | -0.1 | -0.1 | -2.8 | -0.6 | -3.2 | -2.6 | 0.9 | -1.2 | 0.1 | 0.1 | -1.6 | -0.2 | 0.1 | -1.4 | -0.1 | -0.1 | 0.1 | 0.1 | 2.4 | 0.1 |
Delay discounting total patch changes 24 sec | 1.4 | 1.8 | 4.6 | 0.5 | 2.2 | -1.3 | 1.3 | -0.0 | 1.6 | -1.3 | -1.6 | 1.3 | -1.7 | -0.0 | 1.3 | -1.2 | -1.3 | 1.3 | 1.3 | -1.6 | 1.7 | -1.3 | 0.5 | -1.3 | 1.2 | 0.0 | 1.2 | -1.3 | -1.6 | -1.6 | -0.8 | 1.6 | -1.6 | -1.0 | 1.6 | 1.6 | -1.4 | -1.6 | 0.4 | -1.6 |
Short access day 1 locomotion | 1.4 | 1.5 | 5.6 | 2.0 | 0.2 | 1.2 | -0.7 | 2.0 | -0.7 | 0.7 | 0.7 | -0.7 | 0.7 | 2.1 | -0.8 | 1.0 | 1.1 | -0.7 | -1.1 | 0.6 | -0.6 | 0.6 | 1.9 | 1.1 | 2.4 | 2.1 | -1.2 | 1.4 | 0.7 | 0.7 | 1.6 | -0.6 | 0.7 | 1.5 | -0.7 | -0.7 | 0.7 | 0.7 | -2.1 | 0.7 |
Bone: elastic displacement | 1.4 | 1.5 | 3.2 | -1.2 | -1.8 | 1.0 | -1.3 | -0.8 | -1.5 | 1.4 | 1.5 | -1.3 | 1.5 | -0.6 | -1.3 | 1.1 | 1.1 | -1.3 | -1.1 | 1.5 | -1.5 | 1.5 | -1.2 | 1.1 | -0.8 | -0.6 | -0.9 | 0.9 | 1.5 | 1.5 | 0.4 | -1.5 | 1.5 | 0.6 | -1.5 | -1.5 | 1.4 | 1.5 | 0.3 | 1.5 |
Time in closed arm after self-admin | 1.4 | 1.5 | 3.7 | -0.3 | -1.9 | 1.1 | -1.6 | -0.2 | -1.3 | 1.6 | 1.2 | -1.6 | 1.2 | 0.1 | -1.6 | 1.5 | 1.1 | -1.6 | -1.2 | 1.3 | -1.4 | 1.4 | -0.4 | 1.1 | 1.6 | 0.1 | -1.1 | 0.9 | 1.2 | 1.2 | 0.8 | -1.4 | 1.3 | 0.8 | -1.2 | -1.2 | 1.6 | 1.2 | -0.3 | 1.2 |
Distance moved, locomotor task time 1 | 1.4 | 1.5 | 2.3 | -0.4 | 1.5 | -1.4 | 1.3 | -0.7 | 1.3 | -1.3 | -1.3 | 1.3 | -1.3 | -0.8 | 1.3 | -1.3 | -1.4 | 1.3 | 1.4 | -1.3 | 1.2 | -1.3 | -0.3 | -1.3 | -1.3 | -0.8 | 1.4 | -1.3 | -1.3 | -1.3 | -1.2 | 1.3 | -1.3 | -1.3 | 1.3 | 1.3 | -1.4 | -1.3 | 1.1 | -1.3 |
Vertical activity count, locomotor time 2 | 1.4 | 1.5 | 4.4 | 0.7 | 2.1 | -1.2 | 1.5 | 0.2 | 1.4 | -1.4 | -1.4 | 1.5 | -1.4 | 0.2 | 1.4 | -1.3 | -1.2 | 1.5 | 1.2 | -1.5 | 1.4 | -1.6 | 0.7 | -1.1 | -0.1 | 0.2 | 1.1 | -0.9 | -1.3 | -1.3 | -0.7 | 1.5 | -1.5 | -0.8 | 1.4 | 1.3 | -1.6 | -1.3 | 0.3 | -1.3 |
Delay discounting water rate 24 sec | 1.3 | 1.8 | 6.9 | 1.8 | 0.2 | 1.4 | -1.0 | 1.9 | -1.0 | 1.0 | 1.0 | -1.0 | 1.1 | 1.8 | -1.1 | 1.3 | 1.3 | -1.0 | -1.3 | 1.1 | -0.8 | 1.0 | 1.8 | 1.3 | 2.6 | 1.8 | -1.4 | 1.7 | 1.0 | 1.0 | 1.7 | -0.9 | 0.9 | 1.6 | -1.0 | -1.0 | 1.1 | 1.0 | -1.9 | 1.0 |
Locomotor testing rearing | 1.3 | 2.0 | 3.1 | 0.2 | 0.9 | -1.4 | 1.7 | -0.3 | 1.6 | -1.7 | -1.6 | 1.7 | -1.6 | -0.3 | 1.7 | -1.6 | -1.5 | 1.7 | 1.5 | -1.7 | 1.3 | -1.7 | 0.3 | -1.4 | 0.2 | -0.3 | 1.4 | -1.2 | -1.6 | -1.6 | -1.0 | 1.7 | -1.6 | -1.2 | 1.6 | 1.6 | -1.8 | -1.6 | 0.7 | -1.6 |
Conditioned reinforcement - actives | 1.3 | 1.3 | 8.7 | 2.2 | 0.4 | 0.9 | -0.6 | 2.0 | -0.3 | 0.5 | 0.3 | -0.6 | 0.3 | 2.0 | -0.6 | 0.9 | 0.8 | -0.6 | -0.8 | 0.1 | -0.5 | 0.1 | 2.1 | 0.8 | 3.0 | 2.0 | -0.9 | 1.2 | 0.3 | 0.3 | 1.5 | -0.2 | 0.3 | 1.3 | -0.3 | -0.3 | 0.5 | 0.3 | -1.9 | 0.3 |
Locomotion distance, session 3 | 1.3 | 1.4 | 3.3 | 1.7 | -0.5 | 1.3 | -0.9 | 1.8 | -0.9 | 0.9 | 0.9 | -0.9 | 0.9 | 1.7 | -1.0 | 1.2 | 1.2 | -0.9 | -1.2 | 0.9 | -0.9 | 0.9 | 1.6 | 1.3 | 1.7 | 1.8 | -1.3 | 1.5 | 0.9 | 0.9 | 1.6 | -0.8 | 0.9 | 1.5 | -0.9 | -0.9 | 0.9 | 0.9 | -1.8 | 0.9 |
Bone: periosteal estimation | 1.3 | 2.7 | 4.7 | 0.7 | 2.2 | -1.5 | 1.9 | 0.1 | 1.9 | -1.9 | -1.9 | 1.9 | -1.9 | 0.2 | 1.8 | -1.7 | -1.6 | 1.9 | 1.6 | -1.9 | 1.9 | -2.0 | 0.8 | -1.6 | 0.6 | 0.2 | 1.5 | -1.4 | -1.9 | -1.9 | -1.0 | 2.0 | -1.9 | -1.2 | 1.9 | 1.9 | -1.9 | -1.9 | 0.4 | -1.9 |
Weight adjusted by age | 1.3 | 1.4 | 2.5 | 0.0 | 1.6 | -1.2 | 1.6 | -0.4 | 1.3 | -1.5 | -1.2 | 1.6 | -1.2 | -0.4 | 1.6 | -1.5 | -1.2 | 1.6 | 1.2 | -1.3 | 1.3 | -1.3 | 0.1 | -1.1 | -1.0 | -0.4 | 1.2 | -1.0 | -1.2 | -1.2 | -0.9 | 1.4 | -1.3 | -1.1 | 1.2 | 1.2 | -1.4 | -1.2 | 0.6 | -1.2 |
Food seeking constrained by brief footshock | 1.3 | 1.6 | 2.4 | 0.4 | 1.1 | -1.2 | 1.5 | 0.1 | 1.5 | -1.5 | -1.5 | 1.5 | -1.4 | -0.2 | 1.5 | -1.4 | -1.3 | 1.5 | 1.3 | -1.5 | 1.4 | -1.5 | 0.5 | -1.2 | -0.3 | -0.1 | 1.2 | -1.0 | -1.4 | -1.4 | -0.8 | 1.5 | -1.5 | -1.0 | 1.4 | 1.4 | -1.6 | -1.4 | 0.4 | -1.4 |
Zn content in liver | 1.3 | 1.4 | 5.3 | 2.3 | 1.9 | -0.3 | 1.1 | 1.8 | 1.0 | -1.0 | -1.0 | 1.1 | -1.1 | 1.7 | 1.0 | -0.6 | -0.4 | 1.1 | 0.5 | -1.1 | 1.1 | -1.1 | 2.3 | -0.4 | 1.9 | 1.7 | 0.2 | 0.1 | -1.0 | -1.0 | 0.5 | 1.2 | -1.1 | 0.2 | 1.0 | 1.0 | -1.1 | -1.0 | -1.3 | -1.0 |
Right kidney weight | 1.2 | 3.5 | 5.5 | -0.0 | 1.7 | -2.0 | 2.1 | -0.6 | 2.1 | -2.1 | -2.1 | 2.1 | -2.1 | -0.6 | 2.1 | -2.0 | -2.0 | 2.1 | 2.0 | -2.3 | 2.0 | -2.3 | 0.2 | -2.0 | -0.4 | -0.7 | 2.0 | -1.8 | -2.1 | -2.1 | -1.5 | 2.2 | -2.2 | -1.8 | 2.1 | 2.1 | -2.2 | -2.1 | 1.2 | -2.1 |
Delay discounting time to switch 0 sec | 1.2 | 1.8 | 8.8 | -2.2 | -3.0 | 0.6 | -1.5 | -1.7 | -1.2 | 1.5 | 1.2 | -1.5 | 1.2 | -1.5 | -1.4 | 1.1 | 0.7 | -1.5 | -0.7 | 1.3 | -1.4 | 1.4 | -2.3 | 0.6 | -0.9 | -1.6 | -0.5 | 0.1 | 1.2 | 1.2 | -0.3 | -1.5 | 1.3 | 0.1 | -1.2 | -1.2 | 1.4 | 1.2 | 1.1 | 1.2 |
Reaction time trials AUC | 1.2 | 1.7 | 3.0 | 0.8 | -0.4 | 1.4 | -1.2 | 1.1 | -1.4 | 1.3 | 1.4 | -1.2 | 1.6 | 1.0 | -1.3 | 1.4 | 1.4 | -1.2 | -1.4 | 1.6 | -1.1 | 1.4 | 0.8 | 1.4 | 1.0 | 1.0 | -1.4 | 1.7 | 1.4 | 1.4 | 1.4 | -1.3 | 1.3 | 1.4 | -1.4 | -1.4 | 1.2 | 1.4 | -1.3 | 1.4 |
Cocaine response before conditioning | 1.2 | 1.5 | 4.2 | 2.1 | -0.2 | 1.2 | -0.7 | 2.1 | -0.8 | 0.7 | 0.8 | -0.7 | 0.7 | 2.0 | -0.8 | 1.0 | 1.2 | -0.7 | -1.2 | 0.7 | -0.8 | 0.6 | 1.9 | 1.2 | 1.8 | 2.0 | -1.3 | 1.5 | 0.8 | 0.8 | 1.7 | -0.6 | 0.7 | 1.6 | -0.8 | -0.8 | 0.7 | 0.8 | -2.0 | 0.8 |
Total locomotion distance, NPP test | 1.2 | 1.7 | 2.7 | -1.2 | 0.8 | -1.4 | 1.1 | -1.4 | 1.2 | -1.2 | -1.2 | 1.1 | -1.3 | -1.5 | 1.2 | -1.3 | -1.4 | 1.1 | 1.4 | -1.2 | 1.2 | -1.2 | -1.1 | -1.4 | -1.4 | -1.4 | 1.5 | -1.6 | -1.2 | -1.2 | -1.6 | 1.1 | -1.2 | -1.5 | 1.2 | 1.2 | -1.2 | -1.2 | 1.6 | -1.2 |
Delta distance traveled before/after self-admin | 1.2 | 1.3 | 5.8 | 1.8 | 0.3 | 1.2 | -1.0 | 1.8 | -0.5 | 0.9 | 0.5 | -1.0 | 0.4 | 1.8 | -1.1 | 1.2 | 1.1 | -1.0 | -1.1 | 0.8 | -0.4 | 0.8 | 1.5 | 0.9 | 2.4 | 1.7 | -1.2 | 0.9 | 0.5 | 0.5 | 1.5 | -0.6 | 0.7 | 1.3 | -0.5 | -0.5 | 0.9 | 0.5 | -2.0 | 0.5 |
Bouts of movement, locomotor time 2 | 1.2 | 1.3 | 2.2 | -0.2 | 0.2 | -1.2 | 1.2 | -0.4 | 1.3 | -1.2 | -1.3 | 1.2 | -1.3 | -0.6 | 1.2 | -1.1 | -1.3 | 1.2 | 1.3 | -1.1 | 1.3 | -1.1 | -0.1 | -1.3 | -0.4 | -0.6 | 1.2 | -1.2 | -1.4 | -1.4 | -1.1 | 1.3 | -1.3 | -1.2 | 1.5 | 1.4 | -1.1 | -1.4 | 0.8 | -1.4 |
Latency to leave start box in cocaine runway | 1.2 | 1.3 | 5.5 | -2.3 | 0.3 | -1.1 | 0.6 | -2.3 | 0.4 | -0.5 | -0.4 | 0.6 | -0.3 | -2.2 | 0.7 | -1.0 | -1.0 | 0.6 | 1.0 | -0.3 | 0.5 | -0.3 | -2.2 | -0.9 | -2.0 | -2.2 | 1.1 | -1.2 | -0.4 | -0.4 | -1.6 | 0.3 | -0.4 | -1.4 | 0.3 | 0.4 | -0.5 | -0.4 | 2.1 | -0.4 |
Se content in liver | 1.2 | 1.4 | 3.8 | -1.9 | -1.9 | 0.6 | -1.2 | -1.4 | -1.2 | 1.2 | 1.2 | -1.2 | 1.2 | -1.3 | -1.1 | 0.9 | 0.7 | -1.2 | -0.7 | 1.3 | -1.3 | 1.2 | -1.9 | 0.7 | -1.5 | -1.4 | -0.5 | 0.2 | 1.2 | 1.2 | -0.2 | -1.3 | 1.2 | 0.1 | -1.2 | -1.2 | 1.2 | 1.2 | 0.9 | 1.2 |
Parametrial fat weight | 1.1 | 2.2 | 5.6 | -2.0 | 0.3 | -1.6 | 1.4 | -2.2 | 1.1 | -1.4 | -1.1 | 1.4 | -1.2 | -2.0 | 1.5 | -1.7 | -1.5 | 1.4 | 1.5 | -1.2 | 1.0 | -1.2 | -1.8 | -1.5 | -2.4 | -1.9 | 1.6 | -1.7 | -1.1 | -1.1 | -1.9 | 1.0 | -1.1 | -1.8 | 1.1 | 1.1 | -1.3 | -1.1 | 2.1 | -1.1 |
Indifference point AUC | 1.1 | 1.3 | 1.8 | -0.5 | 1.1 | -1.3 | 1.1 | -0.8 | 1.2 | -1.1 | -1.2 | 1.1 | -1.3 | -0.9 | 1.1 | -1.2 | -1.3 | 1.1 | 1.3 | -1.2 | 1.2 | -1.2 | -0.5 | -1.3 | -0.8 | -0.8 | 1.3 | -1.3 | -1.2 | -1.2 | -1.2 | 1.2 | -1.2 | -1.3 | 1.2 | 1.2 | -1.2 | -1.2 | 1.1 | -1.2 |
Social time | 1.1 | 1.5 | 3.7 | -1.6 | -1.9 | 0.9 | -1.3 | -1.2 | -1.4 | 1.3 | 1.4 | -1.3 | 1.3 | -0.9 | -1.2 | 1.0 | 0.9 | -1.3 | -0.9 | 1.5 | -1.4 | 1.4 | -1.6 | 0.9 | -0.4 | -1.0 | -0.8 | 0.5 | 1.4 | 1.4 | 0.1 | -1.5 | 1.4 | 0.4 | -1.4 | -1.4 | 1.4 | 1.4 | 0.5 | 1.4 |
Saline control response | 1.1 | 1.5 | 3.1 | 1.2 | 1.8 | -0.9 | 1.4 | 0.7 | 1.4 | -1.4 | -1.4 | 1.4 | -1.4 | 0.7 | 1.3 | -1.1 | -1.0 | 1.4 | 1.0 | -1.4 | 1.4 | -1.4 | 1.3 | -1.0 | 0.9 | 0.7 | 0.9 | -0.7 | -1.4 | -1.4 | -0.3 | 1.5 | -1.4 | -0.5 | 1.4 | 1.4 | -1.4 | -1.4 | -0.3 | -1.4 |
Incentive Sensitization - Responses | 1.1 | 1.1 | 4.0 | 1.1 | 2.0 | -0.9 | 1.0 | 0.6 | 1.1 | -1.1 | -1.1 | 1.0 | -1.1 | 0.6 | 1.0 | -0.8 | -0.9 | 1.0 | 0.9 | -1.3 | 1.2 | -1.5 | 1.3 | -0.8 | 0.9 | 0.6 | 0.8 | -0.5 | -1.1 | -1.1 | -0.3 | 1.3 | -1.3 | -0.5 | 1.1 | 1.1 | -1.2 | -1.1 | -0.1 | -1.1 |
Total sessions with >9 infusions | 1.1 | 1.2 | 14.3 | 2.2 | 0.9 | 0.6 | -0.1 | 1.8 | 0.1 | 0.1 | -0.1 | -0.1 | -0.2 | 2.0 | -0.2 | 0.4 | 0.5 | -0.1 | -0.5 | -0.0 | 0.1 | -0.0 | 2.0 | 0.5 | 3.8 | 2.0 | -0.7 | 0.7 | -0.1 | -0.1 | 1.2 | 0.2 | -0.1 | 1.0 | 0.1 | 0.1 | 0.2 | -0.1 | -1.9 | -0.1 |
Locomotion velocity, session 1 | 1.1 | 1.1 | 1.5 | 0.1 | -1.2 | 1.1 | -1.2 | 0.4 | -1.2 | 1.2 | 1.2 | -1.2 | 1.2 | 0.5 | -1.2 | 1.2 | 1.1 | -1.2 | -1.1 | 1.2 | -1.2 | 1.2 | 0.1 | 1.1 | 0.3 | 0.4 | -1.1 | 1.1 | 1.2 | 1.2 | 0.9 | -1.2 | 1.2 | 1.0 | -1.2 | -1.2 | 1.2 | 1.2 | -0.7 | 1.2 |
Condit. Reinf. active-inactive response ratio | 1.1 | 1.2 | 2.0 | 0.2 | 1.4 | -1.1 | 1.3 | -0.2 | 1.3 | -1.3 | -1.3 | 1.3 | -1.3 | -0.2 | 1.2 | -1.2 | -1.1 | 1.3 | 1.1 | -1.3 | 1.4 | -1.3 | 0.3 | -1.1 | 0.1 | -0.2 | 1.1 | -1.1 | -1.3 | -1.3 | -0.8 | 1.3 | -1.3 | -0.9 | 1.3 | 1.3 | -1.2 | -1.3 | 0.5 | -1.3 |
Locomotion velocity, NPP test | 1.1 | 1.6 | 3.2 | -1.6 | 0.6 | -1.4 | 1.0 | -1.7 | 1.1 | -1.0 | -1.1 | 1.0 | -1.1 | -1.7 | 1.1 | -1.2 | -1.4 | 1.0 | 1.4 | -1.1 | 1.1 | -1.1 | -1.5 | -1.4 | -1.6 | -1.7 | 1.4 | -1.6 | -1.1 | -1.1 | -1.7 | 1.0 | -1.1 | -1.6 | 1.1 | 1.1 | -1.1 | -1.1 | 1.8 | -1.1 |
Pavlov. Cond. magazine entry latency | 1.1 | 1.4 | 3.3 | 1.8 | 1.8 | -0.6 | 1.3 | 1.3 | 1.2 | -1.3 | -1.2 | 1.3 | -1.2 | 1.2 | 1.2 | -0.9 | -0.7 | 1.3 | 0.7 | -1.2 | 1.2 | -1.2 | 1.8 | -0.7 | 1.3 | 1.3 | 0.5 | -0.3 | -1.2 | -1.2 | 0.1 | 1.3 | -1.2 | -0.1 | 1.2 | 1.2 | -1.2 | -1.2 | -0.8 | -1.2 |
Pavlov. Cond. index score | 1.1 | 1.4 | 3.2 | 1.8 | 1.6 | -0.7 | 1.3 | 1.2 | 1.3 | -1.3 | -1.3 | 1.3 | -1.3 | 1.1 | 1.2 | -1.0 | -0.8 | 1.3 | 0.8 | -1.3 | 1.3 | -1.3 | 1.8 | -0.8 | 1.3 | 1.3 | 0.6 | -0.4 | -1.3 | -1.3 | 0.1 | 1.4 | -1.3 | -0.2 | 1.3 | 1.3 | -1.2 | -1.3 | -0.7 | -1.3 |
Bone: maximum diameter | 1.1 | 2.1 | 4.4 | 1.3 | 2.1 | -1.2 | 1.6 | 0.6 | 1.7 | -1.6 | -1.7 | 1.6 | -1.7 | 0.7 | 1.5 | -1.3 | -1.2 | 1.6 | 1.3 | -1.8 | 1.7 | -1.8 | 1.3 | -1.2 | 1.3 | 0.7 | 1.1 | -0.9 | -1.7 | -1.7 | -0.5 | 1.7 | -1.7 | -0.7 | 1.7 | 1.7 | -1.6 | -1.7 | -0.1 | -1.7 |
Bone: periosteal perimeter | 1.1 | 1.9 | 2.9 | 0.9 | 1.7 | -1.2 | 1.7 | 0.4 | 1.6 | -1.7 | -1.6 | 1.7 | -1.6 | 0.4 | 1.6 | -1.5 | -1.2 | 1.7 | 1.3 | -1.6 | 1.6 | -1.6 | 1.0 | -1.3 | 0.4 | 0.4 | 1.1 | -1.0 | -1.6 | -1.6 | -0.6 | 1.6 | -1.6 | -0.8 | 1.6 | 1.6 | -1.6 | -1.6 | 0.0 | -1.6 |
Delay disc. indifference point, 2s delay | 1.1 | 1.2 | 2.2 | 0.3 | 1.2 | -1.1 | 1.4 | -0.1 | 1.2 | -1.3 | -1.2 | 1.4 | -1.1 | -0.1 | 1.4 | -1.3 | -1.1 | 1.4 | 1.1 | -1.5 | 1.2 | -1.5 | 0.4 | -1.1 | -0.8 | -0.1 | 1.1 | -0.9 | -1.2 | -1.2 | -0.8 | 1.3 | -1.3 | -0.9 | 1.2 | 1.2 | -1.3 | -1.2 | 0.5 | -1.2 |
Seeking ratio, delayed vs. immediate footshock | 1.1 | 1.2 | 3.6 | -0.8 | -1.9 | 1.0 | -1.3 | -0.2 | -1.3 | 1.3 | 1.2 | -1.3 | 1.2 | -0.2 | -1.3 | 1.1 | 1.0 | -1.3 | -1.0 | 1.3 | -1.3 | 1.3 | -1.0 | 1.0 | 0.1 | -0.2 | -1.0 | 0.7 | 1.3 | 1.3 | 0.5 | -1.3 | 1.3 | 0.7 | -1.2 | -1.3 | 1.3 | 1.3 | -0.2 | 1.3 |
Locomotion in novel chamber | 1.1 | 1.3 | 3.1 | 1.4 | -0.3 | 1.3 | -0.9 | 1.8 | -1.0 | 0.9 | 1.0 | -0.9 | 1.0 | 1.5 | -0.9 | 1.2 | 1.3 | -0.9 | -1.3 | 1.1 | -1.0 | 1.1 | 1.4 | 1.2 | 0.2 | 1.4 | -1.3 | 1.6 | 1.0 | 1.0 | 1.5 | -0.9 | 1.0 | 1.4 | -1.0 | -1.0 | 1.1 | 1.0 | -1.5 | 1.0 |
Food consumed during 24 hour testing period | 1.0 | 1.3 | 6.7 | 2.6 | 1.0 | 0.7 | 0.0 | 2.4 | 0.0 | -0.0 | -0.0 | 0.0 | -0.0 | 2.3 | -0.1 | 0.4 | 0.6 | 0.0 | -0.6 | 0.0 | 0.0 | 0.1 | 2.5 | 0.6 | 2.1 | 2.3 | -0.8 | 1.1 | -0.0 | -0.0 | 1.5 | 0.1 | -0.0 | 1.2 | 0.0 | 0.0 | -0.0 | -0.0 | -2.1 | -0.0 |
Mean num. licks in bursts | 1.0 | 1.2 | 6.7 | 2.6 | 1.3 | 0.4 | 0.4 | 2.1 | 0.3 | -0.4 | -0.3 | 0.4 | -0.3 | 2.2 | 0.3 | 0.1 | 0.3 | 0.4 | -0.3 | -0.2 | 0.3 | -0.2 | 2.5 | 0.3 | 2.5 | 2.2 | -0.5 | 0.9 | -0.3 | -0.3 | 1.2 | 0.5 | -0.3 | 1.0 | 0.3 | 0.3 | -0.4 | -0.3 | -2.0 | -0.3 |
Indifference point 0 sec | 1.0 | 1.6 | 7.4 | 2.7 | 1.7 | -0.1 | 1.1 | 2.2 | 0.9 | -1.0 | -0.9 | 1.1 | -0.9 | 2.2 | 1.0 | -0.6 | -0.2 | 1.1 | 0.2 | -1.0 | 0.7 | -0.9 | 2.6 | -0.1 | 2.1 | 2.2 | -0.0 | 0.5 | -0.9 | -0.9 | 0.9 | 1.1 | -0.9 | 0.6 | 0.9 | 0.9 | -1.0 | -0.9 | -1.7 | -0.9 |
Pavlov. Cond. magazine entry latency | 1.0 | 1.1 | 6.2 | 2.5 | 1.3 | 0.3 | 0.3 | 2.0 | 0.4 | -0.3 | -0.4 | 0.3 | -0.4 | 2.1 | 0.2 | 0.1 | 0.3 | 0.3 | -0.2 | -0.3 | 0.4 | -0.3 | 2.4 | 0.3 | 2.4 | 2.1 | -0.4 | 0.7 | -0.4 | -0.4 | 1.1 | 0.5 | -0.4 | 0.9 | 0.4 | 0.4 | -0.3 | -0.4 | -1.8 | -0.4 |
Pavlov. Cond. latency score | 1.0 | 1.3 | 3.2 | 1.8 | 1.5 | -0.6 | 1.2 | 1.2 | 1.2 | -1.2 | -1.2 | 1.2 | -1.2 | 1.2 | 1.2 | -0.9 | -0.7 | 1.2 | 0.7 | -1.2 | 1.2 | -1.2 | 1.8 | -0.7 | 1.3 | 1.3 | 0.5 | -0.3 | -1.2 | -1.2 | 0.1 | 1.3 | -1.2 | -0.2 | 1.2 | 1.2 | -1.2 | -1.2 | -0.8 | -1.2 |
Pavlov. Cond. magazine entry number | 1.0 | 1.3 | 4.2 | -2.0 | -1.8 | 0.4 | -1.1 | -1.5 | -1.1 | 1.1 | 1.1 | -1.1 | 1.0 | -1.5 | -1.0 | 0.7 | 0.5 | -1.1 | -0.5 | 1.1 | -1.0 | 1.1 | -2.0 | 0.5 | -1.6 | -1.6 | -0.3 | 0.0 | 1.1 | 1.1 | -0.4 | -1.2 | 1.1 | -0.1 | -1.1 | -1.1 | 1.0 | 1.1 | 1.1 | 1.1 |
Bone: trabecular number | 1.0 | 1.6 | 2.6 | -0.6 | -1.6 | 1.1 | -1.6 | -0.0 | -1.5 | 1.6 | 1.5 | -1.6 | 1.4 | -0.2 | -1.5 | 1.4 | 1.2 | -1.6 | -1.2 | 1.5 | -1.4 | 1.5 | -0.6 | 1.2 | -0.2 | -0.2 | -1.1 | 0.9 | 1.5 | 1.5 | 0.7 | -1.4 | 1.4 | 0.8 | -1.5 | -1.5 | 1.5 | 1.5 | -0.3 | 1.5 |
Delta time in open arm before/after self-admin | 1.0 | 1.0 | 3.9 | 2.0 | 1.6 | -0.2 | 0.9 | 1.6 | 0.8 | -0.9 | -0.8 | 0.9 | -0.7 | 1.6 | 0.8 | -0.5 | -0.2 | 0.9 | 0.3 | -0.8 | 0.9 | -0.8 | 1.9 | -0.3 | 1.0 | 1.5 | 0.1 | 0.1 | -0.8 | -0.8 | 0.6 | 0.9 | -0.8 | 0.3 | 0.8 | 0.8 | -0.8 | -0.8 | -1.3 | -0.8 |
Total resting periods, locomotor time 2 | 1.0 | 1.0 | 1.5 | -0.5 | 0.1 | -1.1 | 1.0 | -0.7 | 1.1 | -1.1 | -1.1 | 1.0 | -1.1 | -0.8 | 1.0 | -1.1 | -1.1 | 1.0 | 1.1 | -0.9 | 1.1 | -0.9 | -0.4 | -1.2 | -0.6 | -0.8 | 1.1 | -1.1 | -1.1 | -1.1 | -1.1 | 1.1 | -1.1 | -1.1 | 1.2 | 1.1 | -0.9 | -1.1 | 1.0 | -1.1 |
Rest time, locomotor task time 2 | 1.0 | 1.1 | 3.6 | -1.8 | -1.6 | 0.5 | -1.0 | -1.5 | -1.1 | 1.0 | 1.0 | -1.0 | 1.1 | -1.3 | -0.9 | 0.6 | 0.6 | -1.0 | -0.6 | 1.1 | -1.1 | 1.1 | -1.9 | 0.6 | -0.7 | -1.3 | -0.4 | 0.2 | 1.1 | 1.1 | -0.3 | -1.2 | 1.1 | 0.0 | -1.1 | -1.1 | 1.0 | 1.1 | 0.9 | 1.1 |
Locomotion in novel chamber post-restriction | 1.0 | 1.2 | 7.1 | 2.1 | 0.6 | 0.9 | -0.5 | 1.9 | -0.3 | 0.5 | 0.2 | -0.5 | 0.4 | 2.0 | -0.6 | 0.8 | 0.9 | -0.5 | -0.8 | 0.3 | -0.2 | 0.3 | 2.0 | 0.7 | 2.7 | 2.0 | -1.0 | 1.1 | 0.3 | 0.3 | 1.5 | -0.3 | 0.3 | 1.3 | -0.2 | -0.3 | 0.4 | 0.3 | -2.0 | 0.3 |
Tibia length | 0.9 | 2.6 | 9.9 | 2.9 | 0.5 | 1.5 | -0.8 | 2.8 | -0.8 | 0.8 | 0.8 | -0.8 | 0.8 | 2.8 | -1.0 | 1.3 | 1.4 | -0.8 | -1.4 | 0.8 | -0.8 | 0.9 | 2.8 | 1.5 | 3.1 | 2.8 | -1.6 | 2.0 | 0.8 | 0.8 | 2.2 | -0.6 | 0.7 | 2.0 | -0.8 | -0.8 | 0.8 | 0.8 | -2.7 | 0.8 |
Times rat made contact with spout | 0.9 | 1.1 | 3.2 | -1.0 | 0.4 | -1.1 | 1.0 | -1.1 | 0.8 | -1.0 | -0.8 | 1.0 | -0.9 | -1.2 | 1.0 | -1.1 | -1.1 | 1.0 | 1.1 | -0.9 | 0.9 | -0.9 | -1.0 | -1.1 | -1.8 | -1.2 | 1.2 | -1.2 | -0.8 | -0.8 | -1.3 | 0.9 | -0.9 | -1.2 | 0.9 | 0.8 | -1.0 | -0.8 | 1.3 | -0.8 |
Delay discounting total patch changes 18 sec | 0.9 | 1.2 | 2.1 | 1.5 | 1.1 | -0.7 | 1.3 | 0.9 | 1.3 | -1.3 | -1.3 | 1.3 | -1.4 | 1.0 | 1.2 | -1.0 | -0.8 | 1.3 | 0.8 | -1.2 | 1.1 | -1.2 | 1.3 | -0.8 | 0.8 | 1.0 | 0.7 | -0.5 | -1.3 | -1.3 | -0.1 | 1.3 | -1.3 | -0.3 | 1.3 | 1.3 | -1.4 | -1.3 | -0.5 | -1.3 |
Reaction time false alarm rate | 0.9 | 1.3 | 4.7 | -1.9 | -0.8 | -1.1 | 0.6 | -1.9 | 0.6 | -0.6 | -0.6 | 0.6 | -0.6 | -1.9 | 0.7 | -0.9 | -1.0 | 0.6 | 1.0 | -0.9 | 0.4 | -0.8 | -1.8 | -1.0 | -2.2 | -1.8 | 1.1 | -1.4 | -0.6 | -0.6 | -1.5 | 0.5 | -0.6 | -1.4 | 0.6 | 0.6 | -0.6 | -0.6 | 1.9 | -0.6 |
Cocaine response after cond. corrected | 0.9 | 1.0 | 3.7 | -1.9 | -0.0 | -1.0 | 0.5 | -1.9 | 0.5 | -0.5 | -0.4 | 0.5 | -0.5 | -1.8 | 0.6 | -0.8 | -0.9 | 0.5 | 0.9 | -0.5 | 0.5 | -0.6 | -1.8 | -0.9 | -1.7 | -1.8 | 1.0 | -1.2 | -0.4 | -0.4 | -1.4 | 0.4 | -0.5 | -1.3 | 0.5 | 0.4 | -0.5 | -0.4 | 1.8 | -0.4 |
Context. condit. distance diff. score | 0.9 | 1.1 | 4.7 | 2.2 | 0.6 | 0.9 | -0.3 | 2.0 | -0.3 | 0.3 | 0.3 | -0.3 | 0.3 | 2.0 | -0.4 | 0.7 | 0.8 | -0.3 | -0.8 | 0.3 | -0.3 | 0.3 | 2.1 | 0.8 | 2.0 | 1.9 | -0.9 | 1.2 | 0.3 | 0.3 | 1.4 | -0.2 | 0.3 | 1.2 | -0.3 | -0.3 | 0.3 | 0.3 | -1.9 | 0.3 |
Locomotion velocity, hab. session 1 | 0.9 | 1.3 | 2.2 | -1.2 | 0.8 | -1.3 | 1.0 | -1.4 | 1.0 | -1.0 | -1.0 | 1.0 | -1.1 | -1.3 | 1.0 | -1.1 | -1.3 | 1.0 | 1.2 | -1.0 | 1.1 | -1.0 | -1.1 | -1.3 | -1.2 | -1.4 | 1.3 | -1.5 | -1.0 | -1.0 | -1.4 | 1.0 | -1.0 | -1.4 | 1.0 | 1.0 | -1.0 | -1.0 | 1.5 | -1.0 |
Pavlov. Cond. lever-magazine prob. diff. | 0.9 | 1.1 | 2.5 | 1.6 | 1.5 | -0.6 | 1.2 | 1.1 | 1.2 | -1.2 | -1.1 | 1.2 | -1.1 | 1.0 | 1.1 | -0.9 | -0.7 | 1.2 | 0.7 | -1.1 | 1.1 | -1.1 | 1.6 | -0.7 | 1.2 | 1.2 | 0.5 | -0.3 | -1.1 | -1.1 | 0.1 | 1.2 | -1.1 | -0.2 | 1.1 | 1.1 | -1.0 | -1.1 | -0.7 | -1.1 |
Bone: cortical porosity | 0.9 | 0.9 | 2.2 | 1.5 | -0.2 | 1.0 | -0.6 | 1.4 | -0.6 | 0.6 | 0.6 | -0.6 | 0.7 | 1.5 | -0.7 | 0.8 | 1.0 | -0.6 | -1.0 | 0.6 | -0.7 | 0.6 | 1.4 | 1.0 | 1.5 | 1.5 | -1.1 | 1.3 | 0.6 | 0.6 | 1.3 | -0.6 | 0.7 | 1.2 | -0.6 | -0.6 | 0.7 | 0.6 | -1.5 | 0.6 |
Bone: cortical porosity | 0.9 | 0.9 | 2.1 | 1.4 | -0.3 | 1.0 | -0.7 | 1.4 | -0.7 | 0.7 | 0.7 | -0.7 | 0.8 | 1.4 | -0.8 | 0.9 | 1.0 | -0.7 | -1.0 | 0.7 | -0.8 | 0.6 | 1.3 | 1.0 | 1.4 | 1.4 | -1.1 | 1.3 | 0.7 | 0.7 | 1.3 | -0.6 | 0.7 | 1.2 | -0.7 | -0.7 | 0.7 | 0.7 | -1.4 | 0.7 |
Time to tail flick, vehicle, after self-admin | 0.9 | 1.0 | 5.2 | 2.2 | 0.1 | 0.8 | -0.1 | 1.8 | -0.1 | 0.1 | 0.1 | -0.1 | -0.1 | 2.1 | -0.2 | 0.4 | 0.7 | -0.1 | -0.7 | 0.3 | -0.2 | 0.2 | 1.9 | 0.7 | 2.3 | 2.0 | -0.9 | 0.9 | 0.1 | 0.1 | 1.4 | -0.1 | 0.2 | 1.2 | -0.1 | -0.1 | 0.2 | 0.1 | -2.1 | 0.1 |
Vertical activity count, locomotor time 1 | 0.9 | 1.0 | 3.6 | -0.0 | 1.9 | -1.0 | 1.1 | -0.3 | 1.0 | -1.0 | -1.0 | 1.1 | -1.0 | -0.3 | 1.1 | -1.0 | -1.0 | 1.1 | 1.0 | -1.2 | 1.0 | -1.2 | 0.1 | -0.9 | -0.8 | -0.3 | 1.0 | -0.9 | -1.0 | -1.0 | -0.8 | 1.1 | -1.1 | -0.9 | 0.9 | 1.0 | -1.2 | -1.0 | 0.6 | -1.0 |
Delay discounting total patch changes 0 sec | 0.8 | 1.3 | 5.6 | 2.4 | 1.5 | -0.2 | 1.1 | 1.9 | 0.9 | -1.0 | -0.9 | 1.1 | -0.9 | 1.9 | 1.0 | -0.6 | -0.3 | 1.1 | 0.3 | -1.0 | 0.7 | -0.9 | 2.3 | -0.2 | 1.7 | 1.8 | 0.1 | 0.3 | -0.9 | -0.9 | 0.7 | 1.1 | -0.9 | 0.4 | 0.9 | 0.9 | -1.0 | -0.9 | -1.4 | -0.9 |
Reaction time premature initiations | 0.8 | 1.2 | 1.9 | 0.8 | 1.2 | -0.9 | 1.3 | 0.3 | 1.3 | -1.3 | -1.3 | 1.3 | -1.1 | 0.3 | 1.3 | -1.1 | -1.0 | 1.3 | 1.0 | -1.2 | 1.4 | -1.3 | 0.9 | -1.0 | 0.2 | 0.3 | 0.9 | -0.7 | -1.3 | -1.3 | -0.5 | 1.3 | -1.3 | -0.7 | 1.2 | 1.3 | -1.4 | -1.3 | 0.1 | -1.3 |
Incentive Sensitization - Breakpoint | 0.8 | 0.8 | 3.3 | 1.2 | 1.8 | -0.6 | 0.8 | 0.8 | 0.9 | -0.9 | -0.9 | 0.8 | -0.9 | 0.7 | 0.8 | -0.6 | -0.7 | 0.8 | 0.7 | -1.1 | 1.0 | -1.3 | 1.4 | -0.6 | 0.9 | 0.7 | 0.6 | -0.3 | -0.9 | -0.9 | -0.1 | 1.1 | -1.1 | -0.3 | 0.9 | 0.9 | -1.0 | -0.9 | -0.2 | -0.9 |
Short access day 1 total infusions | 0.8 | 0.9 | 5.1 | 1.7 | 1.8 | -0.3 | 0.8 | 1.1 | 0.7 | -0.8 | -0.7 | 0.8 | -0.8 | 1.3 | 0.7 | -0.5 | -0.4 | 0.8 | 0.4 | -0.9 | 0.9 | -0.8 | 1.6 | -0.3 | 2.3 | 1.3 | 0.2 | -0.0 | -0.7 | -0.7 | 0.3 | 0.9 | -0.9 | 0.1 | 0.7 | 0.7 | -0.8 | -0.7 | -0.9 | -0.7 |
Short access day 10 total infusions | 0.8 | 0.9 | 2.7 | 1.0 | 1.5 | -0.7 | 0.8 | 0.5 | 1.1 | -0.8 | -1.1 | 0.8 | -1.1 | 0.7 | 0.7 | -0.6 | -0.7 | 0.8 | 0.7 | -1.1 | 1.0 | -1.1 | 1.0 | -0.7 | 1.6 | 0.7 | 0.6 | -0.6 | -1.1 | -1.1 | -0.2 | 1.1 | -1.1 | -0.3 | 1.1 | 1.1 | -0.8 | -1.1 | -0.3 | -1.1 |
Locomotion velocity, session 3 | 0.8 | 1.0 | 2.0 | 1.3 | -0.6 | 1.0 | -0.8 | 1.4 | -0.8 | 0.8 | 0.8 | -0.8 | 0.7 | 1.3 | -0.9 | 1.0 | 1.0 | -0.8 | -1.0 | 0.8 | -0.7 | 0.8 | 1.2 | 1.0 | 1.3 | 1.4 | -1.1 | 1.2 | 0.8 | 0.8 | 1.3 | -0.7 | 0.7 | 1.2 | -0.8 | -0.8 | 0.8 | 0.8 | -1.4 | 0.8 |
Stereotopy head waving bouts, day 7 | 0.8 | 0.9 | 4.4 | 2.1 | 0.5 | 0.7 | -0.1 | 1.9 | -0.1 | 0.1 | 0.1 | -0.1 | 0.1 | 1.9 | -0.2 | 0.4 | 0.6 | -0.1 | -0.6 | 0.1 | -0.1 | 0.1 | 2.0 | 0.7 | 1.9 | 1.9 | -0.8 | 1.0 | 0.1 | 0.1 | 1.3 | -0.0 | 0.1 | 1.1 | -0.1 | -0.1 | 0.1 | 0.1 | -1.7 | 0.1 |
Total zone transitions, hab. session 2 | 0.8 | 1.0 | 3.2 | 1.8 | 0.2 | 1.0 | -0.6 | 1.7 | -0.5 | 0.5 | 0.5 | -0.6 | 0.5 | 1.8 | -0.6 | 0.8 | 0.9 | -0.6 | -0.9 | 0.5 | -0.5 | 0.5 | 1.7 | 0.9 | 1.8 | 1.7 | -1.0 | 1.2 | 0.5 | 0.5 | 1.4 | -0.4 | 0.5 | 1.3 | -0.5 | -0.5 | 0.6 | 0.5 | -1.7 | 0.5 |
Bone: cortical apparent density | 0.8 | 1.0 | 4.2 | -2.0 | -0.3 | -0.9 | 0.2 | -1.9 | 0.3 | -0.2 | -0.3 | 0.2 | -0.5 | -1.9 | 0.3 | -0.5 | -0.8 | 0.2 | 0.8 | -0.4 | 0.4 | -0.4 | -1.9 | -0.8 | -1.6 | -1.9 | 1.0 | -1.3 | -0.3 | -0.3 | -1.4 | 0.2 | -0.3 | -1.3 | 0.3 | 0.3 | -0.3 | -0.3 | 1.8 | -0.3 |
Fecal boli incidents, locomotor time 1 | 0.8 | 0.9 | 2.7 | 1.4 | -0.3 | 1.0 | -0.7 | 1.5 | -0.6 | 0.7 | 0.6 | -0.7 | 0.6 | 1.4 | -0.8 | 0.9 | 0.9 | -0.7 | -0.9 | 0.6 | -0.6 | 0.6 | 1.3 | 0.9 | 1.6 | 1.4 | -1.0 | 1.1 | 0.5 | 0.5 | 1.3 | -0.6 | 0.6 | 1.2 | -0.6 | -0.5 | 0.7 | 0.5 | -1.5 | 0.5 |
Time >=10cm from walls, locomotor time 1 | 0.8 | 0.8 | 3.7 | 1.8 | 0.1 | 0.7 | -0.2 | 1.7 | -0.3 | 0.2 | 0.3 | -0.2 | 0.2 | 1.7 | -0.3 | 0.5 | 0.7 | -0.2 | -0.6 | 0.2 | -0.2 | 0.1 | 1.7 | 0.6 | 1.9 | 1.7 | -0.8 | 0.9 | 0.3 | 0.3 | 1.2 | -0.1 | 0.2 | 1.0 | -0.1 | -0.3 | 0.2 | 0.3 | -1.6 | 0.3 |
Delay discounting water rate 0 sec | 0.7 | 1.2 | 5.9 | 2.4 | 1.8 | 0.0 | 0.8 | 1.9 | 0.6 | -0.8 | -0.6 | 0.8 | -0.6 | 1.9 | 0.7 | -0.4 | -0.0 | 0.8 | 0.1 | -0.6 | 0.7 | -0.7 | 2.4 | -0.0 | 2.0 | 1.9 | -0.1 | 0.6 | -0.6 | -0.6 | 0.9 | 0.8 | -0.7 | 0.6 | 0.6 | 0.6 | -0.7 | -0.6 | -1.6 | -0.6 |
Delay discounting water rate 12 sec | 0.7 | 1.1 | 6.9 | 2.2 | 1.5 | 0.6 | -0.1 | 1.8 | -0.0 | 0.1 | 0.0 | -0.1 | -0.0 | 2.0 | -0.2 | 0.4 | 0.6 | -0.1 | -0.5 | 0.1 | 0.2 | 0.1 | 2.1 | 0.6 | 2.6 | 2.0 | -0.7 | 0.9 | 0.0 | 0.0 | 1.3 | 0.1 | 0.0 | 1.1 | -0.0 | -0.0 | 0.1 | 0.0 | -1.8 | 0.0 |
Light reinforcement 1 | 0.7 | 1.3 | 13.4 | -2.3 | -1.7 | -0.1 | -0.2 | -1.9 | -0.6 | 0.3 | 0.7 | -0.2 | 0.8 | -1.8 | -0.1 | -0.2 | 0.0 | -0.2 | -0.1 | 0.5 | -0.7 | 0.4 | -2.3 | 0.1 | -3.7 | -1.8 | 0.1 | -0.1 | 0.7 | 0.7 | -0.8 | -0.7 | 0.6 | -0.5 | -0.7 | -0.7 | 0.2 | 0.7 | 1.6 | 0.7 |
Reaction time num false alarms | 0.7 | 1.0 | 5.6 | -2.1 | -1.1 | -0.7 | 0.2 | -1.9 | 0.1 | -0.2 | -0.1 | 0.2 | -0.1 | -1.9 | 0.3 | -0.5 | -0.6 | 0.2 | 0.6 | -0.2 | 0.1 | -0.3 | -2.0 | -0.6 | -2.4 | -1.9 | 0.8 | -0.9 | -0.1 | -0.1 | -1.3 | 0.0 | -0.1 | -1.1 | 0.1 | 0.1 | -0.2 | -0.1 | 1.8 | -0.1 |
Intermittent access day 15 total locomotion | 0.7 | 0.8 | 10.9 | 1.5 | -0.5 | 0.6 | -0.5 | 1.6 | -0.1 | 0.5 | 0.0 | -0.5 | -0.1 | 1.4 | -0.6 | 0.8 | 0.5 | -0.5 | -0.5 | 0.2 | -0.2 | 0.2 | 1.5 | 0.5 | 3.3 | 1.4 | -0.6 | 0.5 | 0.0 | 0.0 | 0.9 | -0.1 | 0.1 | 0.8 | -0.0 | -0.0 | 0.4 | 0.0 | -1.3 | 0.0 |
Compulsive drug intake | 0.7 | 0.7 | 1.1 | 0.3 | -0.5 | 0.9 | -0.7 | 0.4 | -1.0 | 0.8 | 1.0 | -0.7 | 1.0 | 0.5 | -0.7 | 0.8 | 0.9 | -0.7 | -0.9 | 0.8 | -0.9 | 0.7 | 0.3 | 1.0 | -0.0 | 0.5 | -0.9 | 1.1 | 1.0 | 1.0 | 0.9 | -0.9 | 0.9 | 0.9 | -1.0 | -1.0 | 0.8 | 1.0 | -0.7 | 1.0 |
One hour access (shock baseline) | 0.7 | 0.8 | 5.3 | 1.3 | 1.2 | -0.5 | 0.5 | 1.0 | 1.0 | -0.6 | -1.1 | 0.5 | -1.1 | 0.8 | 0.5 | -0.3 | -0.6 | 0.5 | 0.6 | -0.8 | 1.0 | -0.8 | 1.3 | -0.7 | 2.3 | 0.8 | 0.5 | -0.5 | -1.1 | -1.1 | -0.0 | 1.0 | -1.0 | -0.2 | 1.1 | 1.1 | -0.6 | -1.1 | -0.5 | -1.1 |
Stereotopy head waving duration, day 7 | 0.7 | 0.8 | 4.9 | 2.2 | 0.8 | 0.4 | 0.3 | 1.9 | 0.3 | -0.3 | -0.3 | 0.3 | -0.3 | 1.9 | 0.2 | 0.1 | 0.3 | 0.3 | -0.3 | -0.3 | 0.3 | -0.3 | 2.1 | 0.3 | 1.8 | 1.9 | -0.4 | 0.7 | -0.3 | -0.3 | 1.1 | 0.4 | -0.3 | 0.8 | 0.3 | 0.3 | -0.3 | -0.3 | -1.6 | -0.3 |
Condit. Reinf. active minus inactive responses | 0.7 | 0.7 | 1.2 | -0.0 | 0.9 | -0.9 | 0.9 | -0.3 | 1.0 | -1.0 | -1.0 | 0.9 | -1.0 | -0.3 | 0.9 | -0.9 | -0.9 | 0.9 | 0.9 | -1.0 | 1.1 | -1.0 | 0.0 | -0.9 | -0.1 | -0.3 | 0.9 | -0.9 | -1.0 | -1.0 | -0.7 | 1.0 | -1.0 | -0.8 | 1.0 | 1.0 | -0.9 | -1.0 | 0.5 | -1.0 |
Total zone transitions, hab. session 1 | 0.7 | 1.0 | 1.4 | 0.5 | -0.6 | 1.1 | -1.1 | 0.7 | -1.0 | 1.1 | 1.0 | -1.1 | 0.9 | 0.8 | -1.2 | 1.2 | 1.1 | -1.1 | -1.1 | 1.0 | -1.0 | 1.0 | 0.5 | 1.1 | 0.9 | 0.7 | -1.1 | 1.1 | 1.0 | 1.0 | 1.0 | -1.0 | 1.0 | 1.1 | -1.0 | -1.0 | 1.1 | 1.0 | -0.9 | 1.0 |
Pavlov. Cond. lever contacts | 0.7 | 0.8 | 1.3 | 1.0 | 1.0 | -0.7 | 1.0 | 0.6 | 1.1 | -1.0 | -1.1 | 1.0 | -1.1 | 0.5 | 1.0 | -0.8 | -0.8 | 1.0 | 0.8 | -1.1 | 1.0 | -1.1 | 1.0 | -0.8 | 0.7 | 0.7 | 0.7 | -0.5 | -1.1 | -1.1 | -0.2 | 1.1 | -1.1 | -0.4 | 1.1 | 1.1 | -1.0 | -1.1 | -0.2 | -1.1 |
Bone: cortical tissue density | 0.7 | 0.9 | 4.0 | -2.0 | -0.4 | -0.8 | 0.2 | -1.9 | 0.2 | -0.2 | -0.2 | 0.2 | -0.4 | -1.9 | 0.2 | -0.5 | -0.8 | 0.2 | 0.7 | -0.3 | 0.3 | -0.3 | -1.9 | -0.7 | -1.6 | -1.9 | 0.9 | -1.2 | -0.2 | -0.2 | -1.4 | 0.2 | -0.3 | -1.2 | 0.2 | 0.2 | -0.2 | -0.2 | 1.8 | -0.2 |
Diff in mean of infusions in LGA sessions | 0.7 | 0.8 | 5.0 | -2.2 | -0.5 | -0.4 | -0.4 | -2.1 | -0.3 | 0.4 | 0.3 | -0.4 | 0.4 | -1.9 | -0.3 | 0.0 | -0.3 | -0.4 | 0.3 | 0.5 | -0.2 | 0.4 | -2.2 | -0.3 | -0.5 | -2.0 | 0.5 | -0.6 | 0.3 | 0.3 | -1.1 | -0.4 | 0.3 | -0.9 | -0.3 | -0.3 | 0.5 | 0.3 | 1.7 | 0.3 |
Rest time, locomotor task time 1 | 0.7 | 0.7 | 1.9 | 0.3 | -1.2 | 0.9 | -0.8 | 0.4 | -0.9 | 0.8 | 0.8 | -0.8 | 0.8 | 0.5 | -0.8 | 0.8 | 0.9 | -0.8 | -0.9 | 1.0 | -0.7 | 0.9 | 0.2 | 0.8 | 1.4 | 0.5 | -0.9 | 0.8 | 1.0 | 1.0 | 0.8 | -0.9 | 0.9 | 0.9 | -0.8 | -1.0 | 0.9 | 1.0 | -0.7 | 1.0 |
Cd content in liver | 0.7 | 0.8 | 1.7 | -1.2 | 0.2 | -1.0 | 0.7 | -1.2 | 0.7 | -0.7 | -0.7 | 0.7 | -0.7 | -1.3 | 0.7 | -0.9 | -0.9 | 0.7 | 0.9 | -0.7 | 0.8 | -0.7 | -1.1 | -0.9 | -1.2 | -1.2 | 1.0 | -1.1 | -0.7 | -0.7 | -1.2 | 0.6 | -0.7 | -1.1 | 0.7 | 0.7 | -0.7 | -0.7 | 1.3 | -0.7 |
Intraocular pressure | 0.6 | 0.8 | 1.4 | 0.9 | -0.6 | 1.0 | -0.9 | 1.1 | -0.8 | 0.9 | 0.7 | -0.9 | 0.7 | 1.0 | -1.0 | 1.0 | 1.0 | -0.9 | -1.0 | 0.8 | -1.0 | 0.9 | 0.8 | 0.9 | 1.2 | 0.9 | -1.0 | 1.0 | 0.7 | 0.7 | 1.1 | -0.8 | 0.8 | 1.1 | -0.7 | -0.7 | 0.8 | 0.7 | -1.1 | 0.7 |
Extensor digitorum longus weight | 0.6 | 2.3 | 3.4 | -1.2 | 0.7 | -1.7 | 1.5 | -1.4 | 1.5 | -1.5 | -1.5 | 1.5 | -1.5 | -1.6 | 1.5 | -1.6 | -1.7 | 1.5 | 1.7 | -1.6 | 1.6 | -1.6 | -1.1 | -1.7 | -1.7 | -1.4 | 1.7 | -1.9 | -1.5 | -1.5 | -1.8 | 1.4 | -1.5 | -1.8 | 1.5 | 1.5 | -1.5 | -1.5 | 1.7 | -1.5 |
Delay discounting water rate 18 sec | 0.6 | 0.7 | 6.2 | 1.2 | 2.5 | -0.4 | 0.7 | 0.9 | 0.7 | -0.7 | -0.7 | 0.7 | -0.8 | 0.8 | 0.6 | -0.4 | -0.5 | 0.7 | 0.5 | -0.6 | 1.2 | -0.7 | 1.3 | -0.5 | 1.7 | 0.8 | 0.4 | -0.2 | -0.7 | -0.7 | 0.1 | 0.9 | -0.8 | -0.1 | 0.7 | 0.7 | -0.7 | -0.7 | -0.6 | -0.7 |
Delay discounting water rate 6 sec | 0.6 | 0.8 | 5.1 | 1.6 | 0.8 | 0.8 | -0.5 | 1.5 | -0.3 | 0.5 | 0.3 | -0.5 | 0.3 | 1.6 | -0.5 | 0.7 | 0.7 | -0.5 | -0.7 | 0.4 | -0.1 | 0.5 | 1.6 | 0.7 | 2.3 | 1.5 | -0.8 | 1.0 | 0.3 | 0.3 | 1.2 | -0.2 | 0.3 | 1.0 | -0.3 | -0.3 | 0.5 | 0.3 | -1.5 | 0.3 |
Locomotor testing distance | 0.6 | 1.0 | 2.8 | 1.6 | 1.6 | -0.6 | 1.2 | 1.1 | 1.1 | -1.1 | -1.1 | 1.2 | -1.0 | 1.0 | 1.1 | -0.8 | -0.6 | 1.2 | 0.6 | -1.2 | 0.9 | -1.1 | 1.7 | -0.6 | 0.8 | 1.1 | 0.5 | -0.1 | -1.1 | -1.1 | 0.2 | 1.2 | -1.1 | -0.1 | 1.1 | 1.1 | -1.1 | -1.1 | -0.7 | -1.1 |
Condit. Reinf. active-inactive response ratio | 0.6 | 0.6 | 1.8 | 1.3 | 1.3 | -0.3 | 0.7 | 1.0 | 0.8 | -0.7 | -0.8 | 0.7 | -0.8 | 1.0 | 0.7 | -0.5 | -0.4 | 0.7 | 0.4 | -0.7 | 0.8 | -0.6 | 1.3 | -0.4 | 1.2 | 1.0 | 0.3 | -0.1 | -0.8 | -0.8 | 0.2 | 0.8 | -0.8 | 0.0 | 0.8 | 0.8 | -0.7 | -0.8 | -0.7 | -0.8 |
Intermittent access day 15 total infusions | 0.6 | 0.7 | 7.6 | 1.7 | 0.7 | 0.3 | -0.1 | 1.6 | 0.1 | 0.1 | -0.2 | -0.1 | -0.3 | 1.4 | -0.2 | 0.4 | 0.3 | -0.1 | -0.2 | -0.2 | 0.1 | -0.3 | 1.6 | 0.2 | 2.8 | 1.4 | -0.4 | 0.4 | -0.2 | -0.2 | 0.8 | 0.2 | -0.2 | 0.7 | 0.2 | 0.2 | 0.1 | -0.2 | -1.3 | -0.2 |
Cocaine induced anxiety | 0.6 | 0.6 | 3.3 | -1.6 | -1.8 | 0.1 | -0.6 | -1.3 | -0.6 | 0.6 | 0.6 | -0.6 | 0.6 | -1.3 | -0.5 | 0.3 | 0.2 | -0.6 | -0.2 | 0.5 | -0.8 | 0.5 | -1.6 | 0.2 | -1.0 | -1.3 | -0.1 | -0.1 | 0.6 | 0.6 | -0.5 | -0.7 | 0.6 | -0.2 | -0.6 | -0.6 | 0.4 | 0.6 | 1.0 | 0.6 |
Baseline Anxiety | 0.6 | 0.6 | 6.6 | 0.8 | 2.6 | -0.5 | 0.8 | 0.6 | 0.7 | -0.8 | -0.7 | 0.8 | -0.7 | 0.5 | 0.7 | -0.6 | -0.6 | 0.8 | 0.6 | -0.8 | 1.1 | -0.7 | 0.9 | -0.6 | 0.0 | 0.5 | 0.5 | -0.4 | -0.7 | -0.7 | -0.1 | 0.9 | -0.8 | -0.3 | 0.7 | 0.7 | -0.6 | -0.7 | -0.3 | -0.7 |
One hour access (0.3 mA shock) | 0.6 | 0.7 | 5.9 | 1.6 | 1.4 | -0.2 | 0.3 | 1.2 | 0.7 | -0.4 | -0.8 | 0.3 | -0.8 | 1.2 | 0.2 | -0.0 | -0.3 | 0.3 | 0.3 | -0.6 | 0.8 | -0.7 | 1.6 | -0.4 | 2.4 | 1.2 | 0.2 | -0.0 | -0.8 | -0.8 | 0.4 | 0.8 | -0.7 | 0.2 | 0.8 | 0.8 | -0.3 | -0.8 | -0.9 | -0.8 |
Locomotion distance, session 8 | 0.6 | 0.9 | 4.8 | 2.2 | 1.1 | 0.5 | -0.0 | 1.9 | 0.0 | 0.0 | -0.1 | -0.0 | -0.1 | 2.0 | -0.1 | 0.4 | 0.5 | -0.0 | -0.5 | -0.1 | 0.1 | -0.1 | 2.1 | 0.5 | 2.2 | 1.8 | -0.6 | 0.9 | -0.1 | -0.1 | 1.2 | 0.2 | -0.1 | 1.0 | 0.1 | 0.1 | -0.0 | -0.1 | -1.7 | -0.1 |
Time in familiar zone, hab. session 2 | 0.6 | 0.7 | 2.0 | 1.1 | 1.4 | -0.5 | 0.7 | 0.7 | 0.9 | -0.8 | -0.9 | 0.7 | -0.9 | 0.7 | 0.7 | -0.5 | -0.6 | 0.7 | 0.6 | -0.9 | 1.0 | -0.9 | 1.1 | -0.6 | 1.1 | 0.7 | 0.5 | -0.4 | -0.9 | -0.9 | -0.0 | 1.0 | -0.9 | -0.2 | 0.9 | 0.9 | -0.8 | -0.9 | -0.4 | -0.9 |
Pavlov. Cond. change in total contacts | 0.6 | 0.6 | 1.5 | 1.1 | 1.2 | -0.5 | 0.8 | 0.8 | 0.9 | -0.8 | -0.9 | 0.8 | -0.9 | 0.7 | 0.8 | -0.6 | -0.5 | 0.8 | 0.5 | -0.9 | 0.8 | -0.9 | 1.1 | -0.5 | 0.9 | 0.8 | 0.4 | -0.3 | -0.9 | -0.9 | 0.0 | 0.9 | -0.8 | -0.1 | 0.9 | 0.9 | -0.8 | -0.9 | -0.5 | -0.9 |
Pavlov. Cond. response bias | 0.6 | 0.8 | 1.3 | 1.0 | 1.1 | -0.6 | 1.0 | 0.6 | 1.0 | -1.0 | -1.0 | 1.0 | -1.0 | 0.6 | 1.0 | -0.8 | -0.7 | 1.0 | 0.7 | -1.0 | 0.9 | -1.0 | 1.0 | -0.7 | 0.7 | 0.7 | 0.6 | -0.4 | -1.0 | -1.0 | -0.1 | 1.0 | -1.0 | -0.3 | 1.0 | 1.0 | -0.9 | -1.0 | -0.3 | -1.0 |
Bone: connectivity density | 0.6 | 1.0 | 1.3 | 0.6 | -0.7 | 1.1 | -1.1 | 0.9 | -1.0 | 1.1 | 1.0 | -1.1 | 1.0 | 0.8 | -1.1 | 1.1 | 1.0 | -1.1 | -1.0 | 1.0 | -0.9 | 1.1 | 0.5 | 1.1 | 0.7 | 0.8 | -1.0 | 1.1 | 1.0 | 1.0 | 1.0 | -0.9 | 1.0 | 1.0 | -1.0 | -1.0 | 1.0 | 1.0 | -1.0 | 1.0 |
Time to tail flick, test, before self-admin | 0.6 | 0.6 | 1.0 | 0.2 | 0.7 | -0.7 | 1.0 | 0.2 | 1.0 | -1.0 | -1.0 | 1.0 | -0.9 | -0.0 | 1.0 | -0.9 | -0.8 | 1.0 | 0.8 | -0.8 | 0.9 | -0.8 | 0.2 | -0.8 | -0.6 | 0.1 | 0.7 | -0.7 | -1.0 | -1.0 | -0.5 | 0.9 | -0.9 | -0.6 | 0.9 | 1.0 | -1.0 | -1.0 | 0.2 | -1.0 |
Total resting periods, locomotor time 1 | 0.6 | 0.7 | 2.7 | 0.8 | -1.0 | 0.9 | -0.7 | 0.9 | -0.7 | 0.7 | 0.7 | -0.7 | 0.7 | 0.9 | -0.7 | 0.8 | 0.9 | -0.7 | -0.9 | 0.9 | -0.6 | 0.8 | 0.7 | 0.8 | 1.6 | 0.9 | -0.9 | 0.9 | 0.8 | 0.8 | 1.0 | -0.7 | 0.7 | 0.9 | -0.5 | -0.8 | 0.8 | 0.8 | -1.1 | 0.8 |
Latency to leave start box in cocaine runway, M | 0.6 | 0.6 | 1.0 | -0.3 | -0.2 | 0.7 | -0.8 | -0.1 | -0.9 | 0.9 | 1.0 | -0.8 | 0.9 | 0.0 | -0.8 | 0.8 | 0.7 | -0.8 | -0.8 | 0.9 | -0.8 | 0.9 | -0.3 | 0.8 | 0.1 | 0.0 | -0.7 | 0.7 | 0.9 | 0.9 | 0.5 | -0.9 | 0.9 | 0.6 | -1.0 | -0.9 | 0.9 | 0.9 | -0.2 | 0.9 |
Sr content in liver | 0.6 | 0.5 | 1.2 | 0.4 | -0.4 | 0.8 | -0.7 | 0.4 | -0.7 | 0.7 | 0.7 | -0.7 | 0.7 | 0.6 | -0.7 | 0.7 | 0.8 | -0.7 | -0.8 | 0.8 | -0.8 | 0.8 | 0.3 | 0.8 | 1.1 | 0.5 | -0.8 | 0.8 | 0.7 | 0.7 | 0.7 | -0.7 | 0.7 | 0.8 | -0.7 | -0.7 | 0.7 | 0.7 | -0.7 | 0.7 |
Light reinforcement 2 | 0.5 | 0.7 | 3.0 | -0.2 | -0.8 | 0.8 | -0.7 | 0.2 | -1.0 | 0.7 | 1.0 | -0.7 | 1.0 | 0.1 | -0.7 | 0.6 | 0.8 | -0.7 | -0.8 | 0.9 | -1.0 | 0.7 | -0.3 | 0.9 | -1.7 | 0.1 | -0.8 | 0.9 | 1.0 | 1.0 | 0.6 | -1.0 | 1.0 | 0.7 | -1.0 | -1.0 | 0.6 | 1.0 | -0.3 | 1.0 |
Reaction time mean minus median | 0.5 | 0.7 | 1.4 | 0.7 | 0.7 | -0.7 | 1.2 | 0.3 | 0.9 | -1.1 | -0.8 | 1.2 | -1.0 | 0.3 | 1.1 | -1.0 | -0.7 | 1.2 | 0.7 | -1.0 | 0.9 | -1.0 | 0.7 | -0.6 | -0.1 | 0.4 | 0.6 | -0.5 | -0.8 | -0.8 | -0.3 | 1.0 | -0.9 | -0.4 | 0.8 | 0.8 | -1.0 | -0.8 | -0.1 | -0.8 |
Reaction time mean | 0.5 | 0.7 | 6.5 | -1.4 | -0.0 | -0.8 | 0.6 | -1.3 | 0.3 | -0.6 | -0.3 | 0.6 | -0.3 | -1.4 | 0.7 | -0.8 | -0.7 | 0.6 | 0.7 | -0.4 | 0.4 | -0.6 | -1.3 | -0.6 | -2.5 | -1.3 | 0.8 | -0.9 | -0.3 | -0.3 | -1.1 | 0.4 | -0.4 | -1.0 | 0.3 | 0.3 | -0.5 | -0.3 | 1.3 | -0.3 |
Median of all reaction times | 0.5 | 0.7 | 8.1 | -1.6 | -0.3 | -0.5 | 0.2 | -1.4 | -0.1 | -0.1 | 0.2 | 0.2 | 0.1 | -1.6 | 0.3 | -0.5 | -0.4 | 0.2 | 0.4 | -0.0 | -0.0 | -0.2 | -1.6 | -0.3 | -2.8 | -1.4 | 0.5 | -0.7 | 0.2 | 0.2 | -0.9 | -0.1 | 0.0 | -0.8 | -0.1 | -0.2 | -0.1 | 0.2 | 1.3 | 0.2 |
Social response proportion | 0.5 | 0.5 | 1.4 | -0.9 | 1.0 | -0.8 | 0.3 | -1.2 | 0.6 | -0.4 | -0.6 | 0.3 | -0.6 | -0.9 | 0.4 | -0.5 | -0.8 | 0.3 | 0.8 | -0.5 | 0.9 | -0.5 | -0.8 | -0.8 | -0.5 | -1.0 | 0.8 | -1.0 | -0.6 | -0.6 | -1.0 | 0.5 | -0.6 | -0.9 | 0.6 | 0.6 | -0.3 | -0.6 | 1.1 | -0.6 |
Progressive ratio test 2 breakpoint | 0.5 | 0.5 | 1.4 | 0.8 | 0.8 | -0.6 | 0.7 | 0.4 | 0.8 | -0.7 | -0.8 | 0.7 | -0.9 | 0.5 | 0.7 | -0.6 | -0.6 | 0.7 | 0.6 | -1.1 | 0.7 | -1.2 | 0.8 | -0.5 | 0.6 | 0.5 | 0.6 | -0.4 | -0.8 | -0.8 | -0.2 | 0.9 | -0.9 | -0.3 | 0.8 | 0.8 | -0.9 | -0.8 | -0.1 | -0.8 |
Short access total infusions | 0.5 | 0.5 | 2.0 | 1.1 | 1.4 | -0.4 | 0.7 | 0.5 | 0.7 | -0.7 | -0.7 | 0.7 | -0.7 | 0.9 | 0.7 | -0.5 | -0.4 | 0.7 | 0.4 | -0.8 | 0.7 | -0.8 | 1.0 | -0.4 | 1.4 | 0.9 | 0.3 | -0.2 | -0.7 | -0.7 | 0.1 | 0.8 | -0.7 | -0.0 | 0.7 | 0.7 | -0.7 | -0.7 | -0.6 | -0.7 |
Number of responses in last shaping day | 0.5 | 0.6 | 1.1 | 0.1 | 0.4 | -0.8 | 0.9 | -0.2 | 0.8 | -0.9 | -0.8 | 0.9 | -0.8 | -0.1 | 0.9 | -0.9 | -0.8 | 0.9 | 0.8 | -1.0 | 0.7 | -1.1 | 0.1 | -0.7 | -0.7 | -0.1 | 0.7 | -0.6 | -0.8 | -0.8 | -0.6 | 0.9 | -0.9 | -0.6 | 0.8 | 0.8 | -0.9 | -0.8 | 0.5 | -0.8 |
Locomotion distance, session 1 | 0.5 | 0.7 | 1.9 | 1.4 | 0.1 | 0.8 | -0.6 | 1.4 | -0.5 | 0.5 | 0.5 | -0.6 | 0.4 | 1.3 | -0.6 | 0.8 | 0.8 | -0.6 | -0.8 | 0.5 | -0.5 | 0.5 | 1.3 | 0.8 | 1.4 | 1.3 | -0.9 | 1.0 | 0.5 | 0.5 | 1.1 | -0.4 | 0.5 | 1.0 | -0.5 | -0.5 | 0.5 | 0.5 | -1.3 | 0.5 |
Stereotopy head waving bouts, day 3 | 0.5 | 0.6 | 1.2 | -1.0 | 0.2 | -0.8 | 0.7 | -1.0 | 0.6 | -0.7 | -0.6 | 0.7 | -0.6 | -0.9 | 0.7 | -0.8 | -0.8 | 0.7 | 0.8 | -0.6 | 0.6 | -0.6 | -0.9 | -0.8 | -1.1 | -1.0 | 0.8 | -0.9 | -0.6 | -0.6 | -1.0 | 0.6 | -0.6 | -0.9 | 0.6 | 0.6 | -0.6 | -0.6 | 1.1 | -0.6 |
Incentive salience index mean | 0.5 | 0.6 | 1.0 | 0.1 | 0.7 | -0.8 | 0.8 | -0.1 | 0.9 | -0.8 | -0.9 | 0.8 | -0.9 | -0.2 | 0.8 | -0.8 | -0.8 | 0.8 | 0.8 | -0.9 | 1.0 | -0.9 | 0.2 | -0.8 | 0.0 | -0.1 | 0.8 | -0.7 | -0.9 | -0.9 | -0.6 | 0.9 | -0.9 | -0.7 | 0.9 | 0.9 | -0.8 | -0.9 | 0.3 | -0.9 |
Breakpoint value in progressive ratio session | 0.5 | 0.6 | 1.2 | -0.0 | -1.1 | 0.8 | -0.7 | 0.3 | -0.9 | 0.8 | 0.9 | -0.7 | 1.0 | 0.3 | -0.7 | 0.7 | 0.8 | -0.7 | -0.8 | 0.9 | -1.0 | 0.8 | -0.1 | 0.9 | -0.1 | 0.3 | -0.8 | 0.9 | 0.9 | 0.9 | 0.6 | -0.9 | 0.9 | 0.7 | -0.9 | -0.9 | 0.8 | 0.9 | -0.4 | 0.9 |
Delta time to tail flick, vehicle, before/after SA | 0.5 | 0.5 | 2.7 | 1.6 | 0.1 | 0.4 | 0.3 | 1.2 | 0.2 | -0.2 | -0.1 | 0.3 | -0.2 | 1.6 | 0.2 | -0.0 | 0.3 | 0.3 | -0.3 | -0.1 | 0.1 | -0.2 | 1.4 | 0.3 | 1.4 | 1.6 | -0.5 | 0.5 | -0.1 | -0.1 | 0.8 | 0.2 | -0.1 | 0.7 | 0.2 | 0.1 | -0.3 | -0.1 | -1.5 | -0.1 |
Tibialis anterior weight | 0.4 | 1.2 | 1.6 | -0.2 | 0.9 | -1.2 | 1.2 | -0.5 | 1.2 | -1.2 | -1.2 | 1.2 | -1.3 | -0.5 | 1.2 | -1.2 | -1.2 | 1.2 | 1.2 | -1.2 | 1.3 | -1.2 | -0.1 | -1.2 | -0.5 | -0.5 | 1.2 | -1.1 | -1.2 | -1.2 | -1.0 | 1.2 | -1.2 | -1.1 | 1.2 | 1.2 | -1.2 | -1.2 | 0.8 | -1.2 |
Reaction time mean AUC | 0.4 | 0.5 | 6.0 | -1.4 | -0.3 | -0.5 | 0.3 | -1.2 | -0.1 | -0.2 | 0.1 | 0.3 | 0.0 | -1.3 | 0.3 | -0.5 | -0.4 | 0.3 | 0.4 | -0.1 | 0.0 | -0.2 | -1.4 | -0.3 | -2.4 | -1.2 | 0.5 | -0.6 | 0.1 | 0.1 | -0.8 | -0.0 | -0.0 | -0.7 | -0.1 | -0.1 | -0.1 | 0.1 | 1.1 | 0.1 |
Intermitt. access day 15 inactive lever presses | 0.4 | 0.4 | 1.6 | 0.6 | -0.9 | 0.6 | -0.7 | 0.6 | -0.4 | 0.7 | 0.4 | -0.7 | 0.4 | 0.8 | -0.7 | 0.8 | 0.6 | -0.7 | -0.6 | 0.3 | -0.6 | 0.2 | 0.4 | 0.6 | 1.3 | 0.8 | -0.7 | 0.5 | 0.4 | 0.4 | 0.7 | -0.5 | 0.5 | 0.7 | -0.4 | -0.4 | 0.6 | 0.4 | -0.8 | 0.4 |
Intermittent access day 1 total infusions | 0.4 | 0.5 | 2.5 | 1.2 | 0.6 | -0.2 | 0.5 | 0.9 | 0.6 | -0.5 | -0.7 | 0.5 | -0.6 | 1.1 | 0.5 | -0.3 | -0.2 | 0.5 | 0.2 | -0.7 | 0.4 | -0.7 | 1.1 | -0.2 | 1.6 | 1.1 | 0.1 | -0.1 | -0.7 | -0.7 | 0.3 | 0.6 | -0.6 | 0.2 | 0.7 | 0.7 | -0.5 | -0.7 | -0.8 | -0.7 |
Intermittent access terminal intake (last 3 days) | 0.4 | 0.5 | 4.5 | 1.4 | 0.8 | 0.0 | 0.1 | 1.3 | 0.4 | -0.2 | -0.4 | 0.1 | -0.5 | 1.1 | 0.1 | 0.1 | -0.0 | 0.1 | 0.1 | -0.5 | 0.4 | -0.6 | 1.4 | -0.1 | 2.1 | 1.1 | -0.1 | 0.1 | -0.4 | -0.4 | 0.5 | 0.5 | -0.4 | 0.3 | 0.4 | 0.4 | -0.2 | -0.4 | -1.0 | -0.4 |
Lifetime Intake | 0.4 | 0.5 | 3.5 | 1.4 | 1.1 | -0.0 | 0.2 | 1.0 | 0.4 | -0.3 | -0.5 | 0.2 | -0.5 | 1.2 | 0.2 | -0.1 | -0.1 | 0.2 | 0.1 | -0.5 | 0.5 | -0.5 | 1.3 | -0.1 | 1.9 | 1.2 | -0.1 | 0.1 | -0.5 | -0.5 | 0.5 | 0.5 | -0.5 | 0.3 | 0.5 | 0.5 | -0.3 | -0.5 | -1.0 | -0.5 |
Progressive ratio test 2 active lever presses | 0.4 | 0.4 | 1.2 | 0.8 | 0.7 | -0.5 | 0.7 | 0.4 | 0.7 | -0.7 | -0.7 | 0.7 | -0.8 | 0.5 | 0.6 | -0.5 | -0.6 | 0.7 | 0.6 | -1.0 | 0.7 | -1.1 | 0.8 | -0.5 | 0.6 | 0.5 | 0.5 | -0.3 | -0.7 | -0.7 | -0.1 | 0.9 | -0.8 | -0.3 | 0.7 | 0.7 | -0.8 | -0.7 | -0.1 | -0.7 |
Time in novel zone, hab. session 2 | 0.4 | 0.4 | 1.0 | -0.3 | -1.0 | 0.6 | -0.6 | -0.1 | -0.8 | 0.6 | 0.8 | -0.6 | 0.8 | -0.1 | -0.6 | 0.5 | 0.6 | -0.6 | -0.6 | 0.8 | -0.8 | 0.8 | -0.4 | 0.6 | -0.5 | -0.1 | -0.6 | 0.6 | 0.8 | 0.8 | 0.3 | -0.8 | 0.7 | 0.4 | -0.8 | -0.8 | 0.6 | 0.8 | -0.1 | 0.8 |
Total zone transitions, NPP test | 0.4 | 0.6 | 1.0 | 0.9 | -0.3 | 0.8 | -0.7 | 1.0 | -0.6 | 0.7 | 0.6 | -0.7 | 0.6 | 0.9 | -0.8 | 0.8 | 0.8 | -0.7 | -0.8 | 0.6 | -0.6 | 0.6 | 0.8 | 0.8 | 1.0 | 0.9 | -0.8 | 0.9 | 0.6 | 0.6 | 0.9 | -0.6 | 0.6 | 0.9 | -0.6 | -0.6 | 0.7 | 0.6 | -1.0 | 0.6 |
Pavlov. Cond. lever latency | 0.4 | 0.5 | 1.5 | -1.2 | -0.7 | 0.3 | -0.7 | -0.9 | -0.7 | 0.7 | 0.8 | -0.7 | 0.8 | -0.8 | -0.6 | 0.4 | 0.4 | -0.7 | -0.4 | 0.8 | -0.7 | 0.8 | -1.2 | 0.4 | -0.9 | -1.0 | -0.3 | 0.1 | 0.8 | 0.8 | -0.2 | -0.8 | 0.7 | 0.0 | -0.8 | -0.8 | 0.7 | 0.8 | 0.6 | 0.8 |
Pavlov. Cond. intertrial magazine entries | 0.4 | 0.5 | 1.0 | -1.0 | -0.9 | 0.4 | -0.8 | -0.7 | -0.8 | 0.8 | 0.8 | -0.8 | 0.7 | -0.7 | -0.7 | 0.6 | 0.5 | -0.8 | -0.5 | 0.8 | -0.6 | 0.8 | -1.0 | 0.5 | -0.5 | -0.7 | -0.4 | 0.2 | 0.8 | 0.8 | -0.0 | -0.8 | 0.8 | 0.1 | -0.8 | -0.8 | 0.8 | 0.8 | 0.4 | 0.8 |
Bone: apparent density | 0.4 | 0.6 | 0.8 | 0.1 | -0.8 | 0.8 | -0.9 | 0.4 | -0.9 | 0.9 | 0.9 | -0.9 | 0.8 | 0.3 | -0.9 | 0.9 | 0.8 | -0.9 | -0.8 | 0.8 | -0.8 | 0.9 | 0.1 | 0.8 | 0.3 | 0.3 | -0.7 | 0.7 | 0.9 | 0.9 | 0.6 | -0.8 | 0.8 | 0.7 | -0.9 | -0.9 | 0.9 | 0.9 | -0.5 | 0.9 |
Bone: cortical area | 0.4 | 0.6 | 1.1 | 0.3 | 1.0 | -0.8 | 0.8 | -0.0 | 0.9 | -0.8 | -0.9 | 0.8 | -1.0 | 0.0 | 0.8 | -0.7 | -0.8 | 0.8 | 0.8 | -1.0 | 1.0 | -1.0 | 0.4 | -0.8 | 0.7 | 0.0 | 0.8 | -0.7 | -0.9 | -0.9 | -0.5 | 1.0 | -0.9 | -0.6 | 0.9 | 0.9 | -0.9 | -0.9 | 0.2 | -0.9 |
Bone: stiffness | 0.4 | 0.7 | 1.3 | -0.9 | 0.3 | -0.9 | 0.5 | -1.1 | 0.7 | -0.6 | -0.8 | 0.5 | -0.8 | -1.0 | 0.6 | -0.7 | -0.9 | 0.5 | 0.9 | -0.8 | 0.8 | -0.8 | -0.9 | -0.9 | -0.2 | -1.0 | 0.9 | -1.1 | -0.8 | -0.8 | -1.1 | 0.7 | -0.7 | -1.0 | 0.7 | 0.8 | -0.6 | -0.8 | 1.1 | -0.8 |
Distance traveled before self-admin | 0.4 | 0.4 | 2.0 | -1.4 | -1.3 | -0.3 | -0.1 | -1.1 | -0.2 | 0.2 | 0.2 | -0.1 | 0.2 | -1.3 | -0.1 | -0.0 | -0.2 | -0.1 | 0.2 | 0.2 | -0.3 | 0.2 | -1.3 | -0.2 | -1.3 | -1.4 | 0.4 | -0.3 | 0.2 | 0.2 | -0.7 | -0.2 | 0.1 | -0.6 | -0.2 | -0.2 | 0.2 | 0.2 | 1.2 | 0.2 |
Sum of active levers in priming session hrs 5-6 | 0.4 | 0.4 | 2.5 | -0.1 | -0.7 | 0.5 | -0.2 | 0.4 | -0.7 | 0.3 | 0.7 | -0.2 | 0.8 | 0.1 | -0.2 | 0.3 | 0.6 | -0.2 | -0.6 | 0.6 | -0.8 | 0.5 | -0.1 | 0.7 | -1.6 | 0.0 | -0.6 | 0.8 | 0.7 | 0.7 | 0.4 | -0.6 | 0.6 | 0.5 | -0.7 | -0.7 | 0.4 | 0.7 | -0.2 | 0.7 |
Ambulatory time before self-admin | 0.4 | 0.4 | 2.1 | -1.2 | -1.5 | 0.1 | -0.7 | -0.9 | -0.5 | 0.7 | 0.5 | -0.7 | 0.5 | -1.0 | -0.6 | 0.5 | 0.2 | -0.7 | -0.2 | 0.5 | -0.7 | 0.6 | -1.2 | 0.2 | -0.5 | -1.1 | -0.0 | -0.0 | 0.5 | 0.5 | -0.3 | -0.6 | 0.5 | -0.2 | -0.5 | -0.5 | 0.6 | 0.5 | 0.9 | 0.5 |
Delay discount hyperbolic model param | 0.4 | 0.4 | 2.0 | 0.4 | -0.4 | 0.7 | -0.7 | 0.4 | -0.5 | 0.7 | 0.5 | -0.7 | 0.4 | 0.5 | -0.7 | 0.7 | 0.6 | -0.7 | -0.6 | 0.8 | -0.4 | 0.8 | 0.3 | 0.5 | 1.4 | 0.5 | -0.7 | 0.5 | 0.5 | 0.5 | 0.6 | -0.6 | 0.6 | 0.7 | -0.4 | -0.5 | 0.7 | 0.5 | -0.7 | 0.5 |
Time >=10cm from walls, locomotor time 2 | 0.4 | 0.5 | 1.5 | 1.2 | 1.1 | -0.3 | 0.5 | 0.8 | 0.7 | -0.6 | -0.6 | 0.5 | -0.7 | 1.0 | 0.5 | -0.3 | -0.3 | 0.5 | 0.3 | -0.7 | 0.7 | -0.7 | 1.2 | -0.4 | 1.1 | 1.0 | 0.2 | -0.1 | -0.7 | -0.7 | 0.2 | 0.7 | -0.7 | 0.1 | 0.8 | 0.7 | -0.6 | -0.7 | -0.6 | -0.7 |
K content in liver | 0.4 | 0.4 | 0.7 | -0.7 | 0.2 | -0.7 | 0.6 | -0.8 | 0.5 | -0.5 | -0.5 | 0.6 | -0.6 | -0.8 | 0.6 | -0.6 | -0.7 | 0.6 | 0.7 | -0.6 | 0.5 | -0.6 | -0.7 | -0.7 | -0.8 | -0.8 | 0.7 | -0.8 | -0.5 | -0.5 | -0.8 | 0.5 | -0.5 | -0.8 | 0.5 | 0.5 | -0.5 | -0.5 | 0.9 | -0.5 |
Rb content in liver | 0.4 | 0.4 | 1.2 | 0.8 | 1.1 | -0.4 | 0.7 | 0.5 | 0.7 | -0.7 | -0.7 | 0.7 | -0.7 | 0.5 | 0.7 | -0.6 | -0.5 | 0.7 | 0.5 | -0.7 | 0.8 | -0.6 | 0.9 | -0.4 | 1.1 | 0.6 | 0.4 | -0.2 | -0.7 | -0.7 | -0.0 | 0.8 | -0.7 | -0.2 | 0.7 | 0.7 | -0.7 | -0.7 | -0.3 | -0.7 |
Heart weight | 0.3 | 0.4 | 2.3 | 1.4 | 0.8 | 0.1 | 0.2 | 1.3 | 0.3 | -0.2 | -0.3 | 0.2 | -0.4 | 1.2 | 0.1 | 0.1 | 0.0 | 0.2 | -0.0 | -0.6 | 0.4 | -0.5 | 1.5 | 0.1 | 1.2 | 1.2 | -0.1 | 0.2 | -0.3 | -0.3 | 0.6 | 0.4 | -0.4 | 0.4 | 0.3 | 0.3 | -0.2 | -0.3 | -1.1 | -0.3 |
Water consumed over 24 hours | 0.3 | 0.4 | 0.9 | -0.7 | -1.0 | 0.5 | -0.7 | -0.3 | -0.7 | 0.7 | 0.7 | -0.7 | 0.7 | -0.4 | -0.7 | 0.6 | 0.5 | -0.7 | -0.5 | 0.7 | -0.7 | 0.7 | -0.7 | 0.5 | -0.7 | -0.4 | -0.4 | 0.4 | 0.7 | 0.7 | 0.2 | -0.8 | 0.7 | 0.3 | -0.7 | -0.7 | 0.7 | 0.7 | 0.2 | 0.7 |
Reaction time num false alarms AUC | 0.3 | 0.4 | 3.0 | -1.4 | -1.2 | -0.3 | -0.0 | -1.3 | -0.1 | 0.0 | 0.2 | -0.0 | 0.2 | -1.3 | 0.0 | -0.2 | -0.3 | -0.0 | 0.2 | -0.0 | -0.2 | -0.1 | -1.3 | -0.2 | -1.7 | -1.3 | 0.4 | -0.5 | 0.2 | 0.2 | -0.7 | -0.2 | 0.1 | -0.6 | -0.2 | -0.2 | -0.0 | 0.2 | 1.1 | 0.2 |
Reaction time omissions | 0.3 | 0.4 | 2.9 | -0.9 | -0.9 | -0.6 | 0.5 | -0.8 | 0.3 | -0.5 | -0.3 | 0.5 | -0.2 | -0.9 | 0.6 | -0.7 | -0.5 | 0.5 | 0.5 | -0.5 | 0.1 | -0.5 | -0.9 | -0.5 | -1.7 | -0.9 | 0.6 | -0.6 | -0.3 | -0.3 | -0.7 | 0.3 | -0.3 | -0.7 | 0.3 | 0.3 | -0.5 | -0.3 | 0.9 | -0.3 |
Conditioned locomotion | 0.3 | 0.3 | 0.5 | 0.0 | -0.4 | 0.6 | -0.6 | 0.2 | -0.6 | 0.6 | 0.7 | -0.6 | 0.7 | 0.2 | -0.6 | 0.6 | 0.6 | -0.6 | -0.6 | 0.7 | -0.7 | 0.7 | 0.0 | 0.6 | -0.1 | 0.2 | -0.6 | 0.6 | 0.7 | 0.7 | 0.5 | -0.7 | 0.7 | 0.5 | -0.7 | -0.7 | 0.6 | 0.7 | -0.4 | 0.7 |
Intermittent access intake day 1-15 change | 0.3 | 0.3 | 3.9 | 0.9 | 0.8 | 0.2 | -0.2 | 1.0 | -0.0 | 0.2 | -0.0 | -0.2 | -0.2 | 0.7 | -0.3 | 0.4 | 0.2 | -0.2 | -0.2 | 0.1 | 0.2 | -0.0 | 1.0 | 0.1 | 2.0 | 0.7 | -0.2 | 0.3 | -0.0 | -0.0 | 0.5 | 0.1 | -0.1 | 0.3 | 0.0 | 0.0 | 0.2 | -0.0 | -0.7 | -0.0 |
Intermittent access intake escalation | 0.3 | 0.3 | 4.2 | 1.1 | 0.7 | 0.3 | -0.3 | 1.2 | -0.1 | 0.2 | 0.0 | -0.3 | -0.2 | 0.8 | -0.3 | 0.5 | 0.3 | -0.3 | -0.3 | 0.2 | 0.1 | 0.1 | 1.1 | 0.2 | 2.1 | 0.8 | -0.3 | 0.4 | 0.0 | 0.0 | 0.6 | 0.0 | -0.0 | 0.4 | -0.0 | -0.0 | 0.3 | 0.0 | -0.8 | 0.0 |
Intermittent access intake escalation 2 | 0.3 | 0.3 | 2.1 | 0.1 | 1.4 | -0.5 | 0.3 | 0.1 | 0.5 | -0.4 | -0.6 | 0.3 | -0.6 | -0.2 | 0.3 | -0.3 | -0.6 | 0.3 | 0.6 | -0.4 | 0.8 | -0.7 | 0.3 | -0.6 | 1.5 | -0.2 | 0.6 | -0.4 | -0.6 | -0.6 | -0.4 | 0.6 | -0.6 | -0.5 | 0.6 | 0.6 | -0.4 | -0.6 | 0.3 | -0.6 |
Intermitt. access day 1 inactive lever presses | 0.3 | 0.3 | 1.8 | -0.8 | 0.8 | -0.5 | 0.2 | -0.9 | 0.4 | -0.2 | -0.4 | 0.2 | -0.4 | -0.8 | 0.2 | -0.4 | -0.5 | 0.2 | 0.5 | -0.4 | 0.5 | -0.5 | -0.8 | -0.6 | -1.4 | -0.8 | 0.5 | -0.8 | -0.4 | -0.4 | -0.7 | 0.3 | -0.3 | -0.6 | 0.4 | 0.4 | -0.3 | -0.4 | 0.8 | -0.4 |
Intermittent access total infusions | 0.3 | 0.4 | 2.8 | 1.2 | 1.0 | -0.1 | 0.2 | 0.9 | 0.4 | -0.2 | -0.5 | 0.2 | -0.5 | 1.0 | 0.1 | -0.0 | -0.1 | 0.2 | 0.1 | -0.5 | 0.5 | -0.6 | 1.1 | -0.1 | 1.7 | 1.0 | 0.0 | -0.1 | -0.5 | -0.5 | 0.3 | 0.5 | -0.5 | 0.2 | 0.5 | 0.5 | -0.2 | -0.5 | -0.8 | -0.5 |
Intermittent access day 1 locomotion | 0.3 | 0.3 | 2.2 | 0.6 | -1.2 | 0.5 | -0.6 | 0.7 | -0.3 | 0.5 | 0.2 | -0.6 | 0.3 | 0.7 | -0.6 | 0.6 | 0.5 | -0.6 | -0.5 | 0.3 | -0.5 | 0.3 | 0.5 | 0.5 | 1.5 | 0.7 | -0.5 | 0.3 | 0.2 | 0.2 | 0.6 | -0.4 | 0.4 | 0.7 | -0.2 | -0.2 | 0.4 | 0.2 | -0.8 | 0.2 |
Post-drug Anxiety | 0.3 | 0.4 | 1.8 | -1.4 | 0.2 | -0.5 | 0.0 | -1.3 | 0.1 | -0.0 | -0.1 | 0.0 | -0.1 | -1.3 | 0.1 | -0.2 | -0.5 | 0.0 | 0.5 | -0.2 | 0.3 | -0.2 | -1.3 | -0.5 | -0.1 | -1.3 | 0.6 | -0.8 | -0.1 | -0.1 | -0.9 | 0.1 | -0.1 | -0.8 | 0.1 | 0.1 | -0.1 | -0.1 | 1.2 | -0.1 |
Progressive ratio test 2 inactive lever presses | 0.3 | 0.4 | 2.1 | 1.3 | -0.3 | 0.4 | -0.2 | 1.0 | -0.1 | 0.1 | 0.1 | -0.2 | 0.0 | 1.3 | -0.2 | 0.3 | 0.4 | -0.2 | -0.3 | -0.3 | -0.3 | -0.4 | 1.2 | 0.5 | 1.4 | 1.3 | -0.5 | 0.5 | 0.1 | 0.1 | 0.8 | 0.0 | 0.0 | 0.7 | -0.1 | -0.1 | 0.1 | 0.1 | -1.1 | 0.1 |
Locomotion velocity, session 7 | 0.3 | 0.3 | 0.5 | -0.3 | -0.7 | 0.5 | -0.7 | -0.1 | -0.6 | 0.7 | 0.6 | -0.7 | 0.7 | -0.0 | -0.7 | 0.6 | 0.5 | -0.7 | -0.5 | 0.6 | -0.7 | 0.6 | -0.3 | 0.5 | -0.1 | -0.1 | -0.5 | 0.5 | 0.6 | 0.6 | 0.3 | -0.7 | 0.6 | 0.4 | -0.6 | -0.6 | 0.7 | 0.6 | -0.1 | 0.6 |
Time in familiar zone, hab. session 1 | 0.3 | 0.3 | 0.5 | -0.3 | 0.6 | -0.6 | 0.4 | -0.4 | 0.6 | -0.5 | -0.6 | 0.4 | -0.6 | -0.5 | 0.4 | -0.5 | -0.6 | 0.4 | 0.6 | -0.6 | 0.6 | -0.6 | -0.3 | -0.6 | -0.3 | -0.4 | 0.6 | -0.7 | -0.6 | -0.6 | -0.6 | 0.6 | -0.6 | -0.6 | 0.6 | 0.6 | -0.6 | -0.6 | 0.5 | -0.6 |
Total heroin consumption | 0.3 | 0.3 | 1.1 | 0.9 | 0.4 | 0.6 | -0.2 | 1.0 | -0.4 | 0.2 | 0.4 | -0.2 | 0.6 | 0.9 | -0.2 | 0.4 | 0.6 | -0.2 | -0.6 | 0.4 | -0.4 | 0.3 | 0.8 | 0.6 | 1.1 | 0.9 | -0.7 | 0.8 | 0.4 | 0.4 | 0.8 | -0.4 | 0.4 | 0.8 | -0.4 | -0.4 | 0.2 | 0.4 | -0.9 | 0.4 |
Delay disc. indifference point, 0s delay | 0.3 | 0.4 | 1.3 | 0.7 | 1.1 | -0.4 | 0.6 | 0.5 | 0.7 | -0.6 | -0.7 | 0.6 | -0.5 | 0.4 | 0.6 | -0.4 | -0.4 | 0.6 | 0.4 | -0.8 | 0.8 | -0.6 | 0.8 | -0.4 | 0.5 | 0.5 | 0.4 | -0.2 | -0.7 | -0.7 | -0.0 | 0.7 | -0.7 | -0.2 | 0.6 | 0.7 | -0.7 | -0.7 | -0.2 | -0.7 |
Delay disc. indifference point, 24s delay | 0.3 | 0.3 | 1.4 | -0.9 | -1.0 | 0.2 | -0.5 | -0.7 | -0.6 | 0.5 | 0.6 | -0.5 | 0.6 | -0.7 | -0.5 | 0.4 | 0.3 | -0.5 | -0.3 | 0.4 | -0.7 | 0.5 | -0.9 | 0.4 | -1.2 | -0.7 | -0.2 | 0.2 | 0.6 | 0.6 | -0.1 | -0.6 | 0.6 | -0.0 | -0.7 | -0.6 | 0.5 | 0.6 | 0.5 | 0.6 |
Change in fecal boli incidents, locomotor task | 0.3 | 0.3 | 1.4 | -1.2 | -0.2 | -0.2 | -0.4 | -1.1 | -0.1 | 0.3 | 0.0 | -0.4 | -0.0 | -1.1 | -0.3 | 0.1 | -0.2 | -0.4 | 0.2 | 0.3 | 0.1 | 0.3 | -1.2 | -0.3 | -0.2 | -1.1 | 0.3 | -0.6 | 0.1 | 0.1 | -0.6 | -0.2 | 0.1 | -0.5 | -0.0 | -0.1 | 0.3 | 0.1 | 0.9 | 0.1 |
Reaction time mean minus median AUC | 0.2 | 0.3 | 1.6 | 1.3 | 0.4 | 0.0 | 0.6 | 0.9 | 0.3 | -0.5 | -0.3 | 0.6 | -0.4 | 1.0 | 0.6 | -0.4 | -0.0 | 0.6 | 0.0 | -0.3 | 0.4 | -0.4 | 1.2 | 0.1 | 0.7 | 1.1 | -0.1 | 0.3 | -0.3 | -0.3 | 0.5 | 0.4 | -0.4 | 0.3 | 0.2 | 0.3 | -0.5 | -0.3 | -0.9 | -0.3 |
Cocaine response after cond. not corrected | 0.2 | 0.2 | 0.9 | -0.9 | -0.1 | -0.4 | 0.2 | -0.9 | 0.1 | -0.2 | -0.1 | 0.2 | -0.1 | -0.8 | 0.2 | -0.3 | -0.4 | 0.2 | 0.4 | -0.2 | 0.2 | -0.3 | -0.9 | -0.3 | -0.8 | -0.9 | 0.4 | -0.5 | -0.1 | -0.1 | -0.6 | 0.1 | -0.1 | -0.6 | 0.1 | 0.1 | -0.1 | -0.1 | 0.8 | -0.1 |
Conditioned reinforcement - inactives | 0.2 | 0.2 | 0.6 | -0.5 | 0.4 | -0.5 | 0.1 | -0.7 | 0.4 | -0.2 | -0.4 | 0.1 | -0.5 | -0.5 | 0.1 | -0.2 | -0.5 | 0.1 | 0.5 | -0.5 | 0.4 | -0.7 | -0.5 | -0.5 | 0.6 | -0.5 | 0.5 | -0.8 | -0.4 | -0.4 | -0.6 | 0.3 | -0.4 | -0.5 | 0.4 | 0.4 | -0.1 | -0.4 | 0.5 | -0.4 |
Intermittent access total locomotion | 0.2 | 0.3 | 2.4 | 1.1 | -0.4 | 0.2 | -0.0 | 1.0 | 0.2 | 0.0 | -0.2 | -0.0 | -0.2 | 1.0 | -0.1 | 0.2 | 0.1 | -0.0 | -0.1 | -0.1 | -0.0 | -0.2 | 1.0 | 0.2 | 1.5 | 1.0 | -0.2 | 0.2 | -0.2 | -0.2 | 0.5 | 0.2 | -0.1 | 0.4 | 0.2 | 0.2 | -0.1 | -0.2 | -0.8 | -0.2 |
Intermittent access standard deviation | 0.2 | 0.2 | 0.3 | 0.0 | -0.0 | -0.5 | 0.5 | -0.1 | 0.6 | -0.5 | -0.6 | 0.5 | -0.6 | -0.2 | 0.5 | -0.4 | -0.5 | 0.5 | 0.5 | -0.5 | 0.4 | -0.6 | 0.0 | -0.5 | -0.5 | -0.2 | 0.5 | -0.4 | -0.6 | -0.6 | -0.4 | 0.5 | -0.5 | -0.4 | 0.6 | 0.6 | -0.5 | -0.6 | 0.4 | -0.6 |
Progressive ratio test 1 inactive lever presses | 0.2 | 0.2 | 0.9 | 0.6 | 0.4 | -0.3 | 0.4 | 0.1 | 0.5 | -0.4 | -0.5 | 0.4 | -0.5 | 0.6 | 0.4 | -0.4 | -0.3 | 0.4 | 0.3 | -0.7 | 0.3 | -0.8 | 0.4 | -0.2 | 0.9 | 0.6 | 0.2 | -0.3 | -0.5 | -0.5 | -0.0 | 0.5 | -0.4 | 0.0 | 0.5 | 0.5 | -0.5 | -0.5 | -0.4 | -0.5 |
Short access day 10 total locomotion | 0.2 | 0.2 | 1.1 | 0.4 | 0.2 | -0.4 | 0.2 | 0.4 | 0.6 | -0.3 | -0.6 | 0.2 | -0.6 | 0.1 | 0.2 | -0.1 | -0.4 | 0.2 | 0.4 | -0.6 | 0.6 | -0.5 | 0.5 | -0.5 | 1.0 | 0.1 | 0.4 | -0.4 | -0.6 | -0.6 | -0.2 | 0.6 | -0.6 | -0.3 | 0.6 | 0.6 | -0.4 | -0.6 | 0.1 | -0.6 |
Locomotion distance, session 2 | 0.2 | 0.2 | 1.2 | 1.0 | 0.2 | 0.4 | -0.2 | 0.9 | -0.2 | 0.2 | 0.2 | -0.2 | 0.1 | 0.9 | -0.3 | 0.4 | 0.4 | -0.2 | -0.3 | 0.2 | -0.1 | 0.2 | 0.9 | 0.4 | 1.1 | 0.8 | -0.4 | 0.5 | 0.2 | 0.2 | 0.6 | -0.1 | 0.1 | 0.5 | -0.2 | -0.2 | 0.2 | 0.2 | -0.9 | 0.2 |
Locomotion velocity, session 8 | 0.2 | 0.2 | 1.3 | 1.1 | 0.3 | 0.3 | -0.1 | 1.0 | 0.0 | 0.1 | -0.0 | -0.1 | -0.0 | 1.1 | -0.1 | 0.3 | 0.3 | -0.1 | -0.3 | -0.0 | -0.0 | -0.0 | 1.1 | 0.3 | 1.1 | 1.0 | -0.4 | 0.5 | -0.0 | -0.0 | 0.7 | 0.0 | 0.0 | 0.5 | 0.0 | 0.0 | 0.1 | -0.0 | -0.9 | -0.0 |
Condit. Reinf. active responses | 0.2 | 0.2 | 0.4 | -0.2 | 0.4 | -0.5 | 0.5 | -0.3 | 0.5 | -0.5 | -0.5 | 0.5 | -0.5 | -0.4 | 0.5 | -0.5 | -0.5 | 0.5 | 0.5 | -0.5 | 0.6 | -0.5 | -0.2 | -0.6 | -0.2 | -0.3 | 0.5 | -0.6 | -0.5 | -0.5 | -0.5 | 0.5 | -0.5 | -0.5 | 0.5 | 0.5 | -0.5 | -0.5 | 0.4 | -0.5 |
Bone surface | 0.2 | 0.3 | 1.3 | 1.1 | 0.9 | -0.1 | 0.4 | 0.9 | 0.5 | -0.4 | -0.5 | 0.4 | -0.5 | 0.9 | 0.3 | -0.2 | -0.2 | 0.4 | 0.2 | -0.5 | 0.5 | -0.5 | 1.1 | -0.2 | 1.0 | 0.9 | 0.1 | 0.0 | -0.5 | -0.5 | 0.3 | 0.6 | -0.5 | 0.1 | 0.5 | 0.5 | -0.4 | -0.5 | -0.7 | -0.5 |
Bone: cortical thickness | 0.2 | 0.2 | 1.3 | 0.6 | -0.1 | 0.5 | -0.4 | 0.6 | -0.4 | 0.4 | 0.4 | -0.4 | 0.3 | 0.6 | -0.4 | 0.5 | 0.5 | -0.4 | -0.5 | 0.3 | -0.3 | 0.3 | 0.6 | 0.5 | 1.1 | 0.6 | -0.5 | 0.6 | 0.4 | 0.4 | 0.6 | -0.3 | 0.3 | 0.5 | -0.4 | -0.4 | 0.4 | 0.4 | -0.7 | 0.4 |
Bone: trabecular spacing | 0.2 | 0.3 | 1.3 | 1.1 | 0.8 | 0.1 | 0.3 | 0.8 | 0.3 | -0.3 | -0.3 | 0.3 | -0.2 | 1.0 | 0.3 | -0.1 | 0.0 | 0.3 | -0.0 | -0.3 | 0.2 | -0.3 | 1.1 | 0.0 | 1.1 | 1.0 | -0.1 | 0.3 | -0.3 | -0.3 | 0.5 | 0.3 | -0.3 | 0.3 | 0.3 | 0.3 | -0.3 | -0.3 | -0.8 | -0.3 |
Time to tail flick, vehicle, before self-admin | 0.2 | 0.2 | 0.3 | 0.0 | -0.5 | 0.4 | -0.5 | 0.4 | -0.4 | 0.5 | 0.4 | -0.5 | 0.3 | 0.2 | -0.5 | 0.5 | 0.4 | -0.5 | -0.4 | 0.5 | -0.4 | 0.5 | -0.0 | 0.4 | 0.3 | -0.0 | -0.4 | 0.3 | 0.4 | 0.4 | 0.3 | -0.4 | 0.4 | 0.3 | -0.4 | -0.4 | 0.6 | 0.4 | -0.3 | 0.4 |
Area under the delay curve | 0.2 | 0.2 | 1.7 | -0.4 | 0.2 | -0.4 | 0.5 | -0.4 | 0.3 | -0.4 | -0.3 | 0.5 | -0.2 | -0.5 | 0.5 | -0.5 | -0.4 | 0.5 | 0.4 | -0.5 | 0.1 | -0.5 | -0.3 | -0.2 | -1.3 | -0.5 | 0.4 | -0.3 | -0.3 | -0.3 | -0.5 | 0.3 | -0.3 | -0.5 | 0.1 | 0.3 | -0.4 | -0.3 | 0.6 | -0.3 |
Delay discount exponential model param | 0.2 | 0.2 | 2.1 | 0.5 | -0.1 | 0.4 | -0.5 | 0.4 | -0.2 | 0.4 | 0.2 | -0.5 | 0.2 | 0.5 | -0.5 | 0.5 | 0.4 | -0.5 | -0.4 | 0.5 | -0.1 | 0.5 | 0.4 | 0.2 | 1.4 | 0.5 | -0.4 | 0.3 | 0.2 | 0.2 | 0.5 | -0.3 | 0.3 | 0.5 | -0.1 | -0.2 | 0.4 | 0.2 | -0.6 | 0.2 |
Progressive ratio | 0.2 | 0.3 | 0.6 | 0.4 | -0.5 | 0.6 | -0.4 | 0.5 | -0.6 | 0.4 | 0.6 | -0.4 | 0.6 | 0.6 | -0.4 | 0.5 | 0.6 | -0.4 | -0.6 | 0.5 | -0.6 | 0.5 | 0.3 | 0.7 | -0.3 | 0.4 | -0.6 | 0.7 | 0.6 | 0.6 | 0.6 | -0.5 | 0.5 | 0.6 | -0.6 | -0.6 | 0.5 | 0.6 | -0.6 | 0.6 |
BMI with tail | 0.1 | 0.4 | 0.9 | -0.4 | -1.0 | -0.6 | 0.6 | -0.6 | 0.6 | -0.6 | -0.6 | 0.6 | -0.6 | -0.5 | 0.7 | -0.7 | -0.6 | 0.6 | 0.6 | -0.7 | 0.2 | -0.8 | -0.4 | -0.6 | 0.1 | -0.6 | 0.6 | -0.7 | -0.6 | -0.6 | -0.6 | 0.6 | -0.6 | -0.6 | 0.6 | 0.6 | -0.6 | -0.6 | 0.6 | -0.6 |
Glucose | 0.1 | 0.1 | 0.2 | 0.3 | -0.2 | 0.4 | -0.4 | 0.4 | -0.3 | 0.4 | 0.3 | -0.4 | 0.3 | 0.4 | -0.4 | 0.4 | 0.4 | -0.4 | -0.4 | 0.3 | -0.4 | 0.3 | 0.3 | 0.4 | 0.4 | 0.4 | -0.4 | 0.4 | 0.3 | 0.3 | 0.4 | -0.3 | 0.4 | 0.4 | -0.4 | -0.3 | 0.4 | 0.3 | -0.4 | 0.3 |
Length without tail | 0.1 | 0.1 | 0.6 | -0.6 | -0.8 | 0.1 | -0.4 | -0.5 | -0.3 | 0.4 | 0.3 | -0.4 | 0.3 | -0.4 | -0.4 | 0.3 | 0.1 | -0.4 | -0.2 | 0.2 | -0.4 | 0.2 | -0.6 | 0.1 | 0.0 | -0.4 | -0.1 | -0.1 | 0.3 | 0.3 | -0.1 | -0.4 | 0.3 | -0.0 | -0.3 | -0.3 | 0.3 | 0.3 | 0.2 | 0.3 |
Delay discounting total patch changes 6 sec | 0.1 | 0.2 | 2.3 | 1.0 | 0.7 | 0.1 | 0.1 | 0.8 | 0.2 | -0.1 | -0.2 | 0.1 | -0.3 | 0.7 | 0.1 | 0.1 | 0.0 | 0.1 | -0.0 | -0.3 | 0.2 | -0.1 | 1.0 | 0.0 | 1.5 | 0.8 | -0.1 | 0.2 | -0.2 | -0.2 | 0.4 | 0.3 | -0.3 | 0.2 | 0.2 | 0.2 | -0.2 | -0.2 | -0.6 | -0.2 |
Locomotor activity | 0.1 | 0.2 | 1.3 | 1.1 | 0.4 | 0.2 | 0.2 | 1.0 | 0.1 | -0.2 | -0.1 | 0.2 | 0.0 | 0.8 | 0.1 | 0.1 | 0.2 | 0.2 | -0.2 | -0.2 | -0.2 | -0.2 | 1.1 | 0.2 | 0.4 | 0.9 | -0.2 | 0.6 | -0.1 | -0.1 | 0.6 | 0.1 | -0.1 | 0.4 | 0.1 | 0.1 | -0.1 | -0.1 | -0.7 | -0.1 |
Intermitt. access escalation Index | 0.1 | 0.1 | 2.6 | 0.6 | 0.2 | 0.0 | -0.0 | 0.5 | 0.1 | 0.0 | -0.1 | -0.0 | -0.1 | 0.4 | -0.1 | 0.1 | 0.0 | -0.0 | -0.0 | -0.2 | 0.2 | -0.0 | 0.6 | 0.0 | 1.6 | 0.4 | -0.0 | 0.1 | -0.1 | -0.1 | 0.2 | 0.2 | -0.1 | 0.1 | 0.1 | 0.1 | -0.0 | -0.1 | -0.4 | -0.1 |
Progressive ratio test 1 active lever presses | 0.1 | 0.1 | 0.8 | -0.2 | -0.7 | 0.1 | -0.4 | -0.1 | -0.2 | 0.3 | 0.2 | -0.4 | 0.1 | -0.1 | -0.4 | 0.3 | 0.1 | -0.4 | -0.1 | 0.1 | -0.2 | 0.1 | -0.3 | 0.1 | 0.9 | -0.1 | -0.1 | -0.2 | 0.2 | 0.2 | -0.0 | -0.2 | 0.2 | 0.1 | -0.2 | -0.2 | 0.3 | 0.2 | -0.0 | 0.2 |
Short access day 1 total inactive lever presses | 0.1 | 0.1 | 1.4 | -0.1 | 0.1 | 0.3 | -0.4 | -0.4 | -0.2 | 0.4 | 0.2 | -0.4 | 0.3 | 0.1 | -0.4 | 0.3 | 0.3 | -0.4 | -0.3 | 0.3 | -0.2 | 0.3 | -0.2 | 0.2 | 1.2 | 0.1 | -0.3 | 0.1 | 0.2 | 0.2 | 0.2 | -0.4 | 0.3 | 0.3 | -0.2 | -0.2 | 0.4 | 0.2 | -0.3 | 0.2 |
Short access day 10 total inactive lever presses | 0.1 | 0.1 | 0.2 | -0.2 | 0.1 | 0.3 | -0.5 | -0.2 | -0.3 | 0.4 | 0.3 | -0.5 | 0.4 | -0.1 | -0.5 | 0.4 | 0.3 | -0.5 | -0.3 | 0.5 | -0.3 | 0.4 | -0.1 | 0.2 | 0.1 | -0.1 | -0.3 | 0.3 | 0.3 | 0.3 | 0.2 | -0.4 | 0.4 | 0.2 | -0.3 | -0.3 | 0.5 | 0.3 | -0.0 | 0.3 |
Short access total locomotion | 0.1 | 0.1 | 1.8 | 0.5 | -0.5 | 0.1 | -0.1 | 0.6 | 0.1 | 0.1 | -0.1 | -0.1 | -0.1 | 0.4 | -0.1 | 0.2 | 0.1 | -0.1 | -0.0 | -0.2 | -0.0 | -0.1 | 0.5 | 0.1 | 1.3 | 0.4 | -0.1 | -0.0 | -0.1 | -0.1 | 0.2 | 0.1 | -0.1 | 0.2 | 0.1 | 0.1 | -0.0 | -0.1 | -0.4 | -0.1 |
Stereotopy head waving duration, day 3 | 0.1 | 0.1 | 0.3 | 0.4 | -0.2 | 0.4 | -0.3 | 0.4 | -0.3 | 0.3 | 0.3 | -0.3 | 0.3 | 0.5 | -0.3 | 0.3 | 0.4 | -0.3 | -0.4 | 0.3 | -0.3 | 0.3 | 0.4 | 0.4 | 0.4 | 0.5 | -0.4 | 0.5 | 0.3 | 0.3 | 0.5 | -0.3 | 0.3 | 0.4 | -0.3 | -0.3 | 0.3 | 0.3 | -0.5 | 0.3 |
Condit. Reinf. inactive responses | 0.1 | 0.1 | 0.2 | -0.1 | -0.4 | 0.3 | -0.3 | 0.0 | -0.3 | 0.3 | 0.3 | -0.3 | 0.3 | -0.0 | -0.3 | 0.3 | 0.3 | -0.3 | -0.3 | 0.3 | -0.4 | 0.3 | -0.1 | 0.3 | -0.1 | 0.0 | -0.3 | 0.3 | 0.3 | 0.3 | 0.2 | -0.3 | 0.3 | 0.2 | -0.3 | -0.3 | 0.3 | 0.3 | -0.1 | 0.3 |
Condit. Reinf. lever presses | 0.1 | 0.1 | 0.2 | 0.2 | 0.0 | -0.3 | 0.3 | 0.1 | 0.4 | -0.3 | -0.4 | 0.3 | -0.4 | -0.0 | 0.2 | -0.2 | -0.3 | 0.3 | 0.3 | -0.4 | 0.4 | -0.4 | 0.2 | -0.3 | 0.2 | 0.1 | 0.3 | -0.3 | -0.4 | -0.4 | -0.1 | 0.4 | -0.4 | -0.2 | 0.4 | 0.4 | -0.3 | -0.4 | 0.0 | -0.4 |
Time in novel zone, hab. session 1 | 0.1 | 0.1 | 0.4 | -0.5 | -0.5 | -0.0 | 0.1 | -0.4 | -0.1 | -0.0 | 0.2 | 0.1 | 0.2 | -0.4 | 0.1 | -0.1 | -0.0 | 0.1 | 0.0 | 0.2 | -0.2 | 0.2 | -0.5 | 0.0 | -0.6 | -0.5 | 0.0 | -0.1 | 0.2 | 0.2 | -0.2 | -0.2 | 0.1 | -0.2 | -0.2 | -0.2 | 0.1 | 0.2 | 0.4 | 0.2 |
Time in novel zone, NPP test | 0.1 | 0.1 | 0.3 | 0.6 | 0.2 | 0.2 | 0.1 | 0.5 | -0.0 | -0.1 | 0.0 | 0.1 | 0.1 | 0.5 | 0.1 | 0.0 | 0.2 | 0.1 | -0.2 | 0.0 | -0.0 | 0.0 | 0.5 | 0.2 | 0.3 | 0.5 | -0.2 | 0.3 | 0.0 | 0.0 | 0.3 | 0.0 | 0.0 | 0.3 | -0.0 | -0.0 | -0.1 | 0.0 | -0.5 | 0.0 |
Bone volume | 0.1 | 0.2 | 0.8 | 0.9 | 0.6 | -0.0 | 0.2 | 0.8 | 0.2 | -0.2 | -0.2 | 0.2 | -0.3 | 0.7 | 0.1 | -0.0 | -0.0 | 0.2 | 0.0 | -0.3 | 0.3 | -0.3 | 0.9 | -0.0 | 0.8 | 0.7 | -0.0 | 0.2 | -0.2 | -0.2 | 0.3 | 0.3 | -0.3 | 0.2 | 0.3 | 0.2 | -0.2 | -0.2 | -0.6 | -0.2 |
Bone: cortical thickness | 0.1 | 0.1 | 0.3 | -0.4 | -0.5 | 0.2 | -0.5 | -0.3 | -0.4 | 0.5 | 0.4 | -0.5 | 0.3 | -0.3 | -0.5 | 0.4 | 0.2 | -0.5 | -0.2 | 0.3 | -0.3 | 0.3 | -0.3 | 0.2 | 0.4 | -0.3 | -0.2 | 0.1 | 0.4 | 0.4 | 0.0 | -0.4 | 0.3 | 0.1 | -0.4 | -0.4 | 0.5 | 0.4 | 0.1 | 0.4 |
Bone: maximum moment | 0.1 | 0.1 | 0.5 | 0.3 | 0.4 | -0.2 | 0.2 | 0.1 | 0.3 | -0.3 | -0.3 | 0.2 | -0.3 | 0.2 | 0.2 | -0.2 | -0.2 | 0.2 | 0.2 | -0.4 | 0.3 | -0.4 | 0.3 | -0.2 | 0.7 | 0.2 | 0.2 | -0.2 | -0.3 | -0.3 | -0.1 | 0.4 | -0.3 | -0.1 | 0.3 | 0.3 | -0.2 | -0.3 | -0.1 | -0.3 |
Bone: trabecular thickness | 0.1 | 0.1 | 0.4 | -0.7 | -0.2 | -0.3 | 0.2 | -0.7 | 0.0 | -0.1 | -0.0 | 0.2 | -0.1 | -0.6 | 0.2 | -0.2 | -0.2 | 0.2 | 0.2 | -0.1 | 0.1 | -0.1 | -0.6 | -0.2 | -0.6 | -0.6 | 0.3 | -0.4 | -0.0 | -0.0 | -0.4 | 0.1 | -0.1 | -0.4 | 0.0 | 0.0 | -0.1 | -0.0 | 0.6 | -0.0 |
Extinction: sum of active levers before priming | 0.1 | 0.1 | 1.9 | -0.4 | -0.3 | -0.2 | 0.2 | -0.2 | 0.1 | -0.2 | -0.1 | 0.2 | -0.1 | -0.3 | 0.3 | -0.3 | -0.2 | 0.2 | 0.2 | -0.1 | 0.0 | -0.1 | -0.4 | -0.1 | -1.4 | -0.3 | 0.2 | -0.2 | -0.1 | -0.1 | -0.3 | 0.1 | -0.1 | -0.2 | 0.0 | 0.1 | -0.2 | -0.1 | 0.3 | -0.1 |
Delta time to tail flick, test, before/after SA | 0.1 | 0.1 | 0.8 | -0.6 | 0.4 | -0.2 | -0.0 | -0.9 | 0.0 | 0.0 | -0.0 | -0.0 | -0.0 | -0.6 | 0.0 | -0.1 | -0.2 | -0.0 | 0.2 | -0.1 | 0.2 | -0.1 | -0.6 | -0.2 | 0.2 | -0.7 | 0.3 | -0.3 | -0.0 | -0.0 | -0.4 | 0.0 | -0.1 | -0.4 | 0.1 | 0.0 | 0.0 | -0.0 | 0.6 | -0.0 |
Delay disc. indifference point, 16s delay | 0.1 | 0.1 | 0.2 | -0.1 | -0.2 | 0.3 | -0.3 | 0.0 | -0.3 | 0.4 | 0.3 | -0.3 | 0.4 | 0.0 | -0.3 | 0.3 | 0.3 | -0.3 | -0.3 | 0.3 | -0.5 | 0.2 | -0.1 | 0.4 | -0.3 | 0.0 | -0.3 | 0.3 | 0.3 | 0.3 | 0.2 | -0.4 | 0.4 | 0.2 | -0.5 | -0.3 | 0.3 | 0.3 | -0.1 | 0.3 |
Delay disc. indifference point, 8s delay | 0.1 | 0.1 | 1.5 | -0.0 | 0.2 | -0.2 | 0.4 | -0.0 | 0.1 | -0.3 | -0.1 | 0.4 | -0.0 | -0.1 | 0.4 | -0.4 | -0.2 | 0.4 | 0.2 | -0.4 | -0.0 | -0.4 | 0.0 | 0.1 | -1.2 | -0.1 | 0.2 | 0.0 | -0.1 | -0.1 | -0.1 | 0.2 | -0.2 | -0.2 | -0.0 | 0.1 | -0.4 | -0.1 | 0.2 | -0.1 |
Bouts of movement, locomotor time 1 | 0.1 | 0.1 | 1.2 | 0.7 | -0.5 | 0.3 | -0.1 | 0.7 | -0.2 | 0.1 | 0.1 | -0.1 | 0.1 | 0.6 | -0.1 | 0.2 | 0.3 | -0.1 | -0.3 | 0.3 | -0.0 | 0.1 | 0.6 | 0.2 | 1.1 | 0.6 | -0.3 | 0.4 | 0.2 | 0.2 | 0.5 | -0.1 | 0.1 | 0.4 | 0.0 | -0.2 | 0.1 | 0.2 | -0.6 | 0.2 |
Run reversals in cocaine runway, males | 0.1 | 0.1 | 1.4 | -0.1 | -1.2 | 0.3 | -0.3 | -0.2 | -0.2 | 0.3 | 0.2 | -0.3 | 0.2 | 0.1 | -0.3 | 0.3 | 0.3 | -0.3 | -0.3 | 0.2 | -0.3 | 0.3 | -0.2 | 0.2 | 0.6 | 0.0 | -0.3 | 0.1 | 0.2 | 0.2 | 0.2 | -0.3 | 0.3 | 0.2 | -0.2 | -0.2 | 0.3 | 0.2 | -0.1 | 0.2 |
Fe content in liver | 0.1 | 0.1 | 0.1 | -0.3 | 0.1 | -0.3 | 0.3 | -0.4 | 0.2 | -0.3 | -0.2 | 0.3 | -0.3 | -0.3 | 0.3 | -0.3 | -0.3 | 0.3 | 0.3 | -0.3 | 0.2 | -0.3 | -0.3 | -0.3 | -0.2 | -0.3 | 0.3 | -0.4 | -0.2 | -0.2 | -0.3 | 0.2 | -0.2 | -0.3 | 0.2 | 0.2 | -0.3 | -0.2 | 0.4 | -0.2 |
Mg content in liver | 0.1 | 0.1 | 0.2 | 0.3 | 0.5 | -0.3 | 0.4 | 0.1 | 0.4 | -0.4 | -0.4 | 0.4 | -0.4 | 0.1 | 0.4 | -0.4 | -0.3 | 0.4 | 0.3 | -0.4 | 0.4 | -0.5 | 0.3 | -0.3 | 0.3 | 0.1 | 0.3 | -0.2 | -0.4 | -0.4 | -0.1 | 0.4 | -0.4 | -0.2 | 0.4 | 0.4 | -0.4 | -0.4 | -0.0 | -0.4 |
Na content in liver | 0.1 | 0.1 | 0.5 | 0.7 | 0.1 | 0.3 | -0.1 | 0.6 | -0.1 | 0.1 | 0.1 | -0.1 | 0.1 | 0.7 | -0.1 | 0.2 | 0.3 | -0.1 | -0.2 | 0.1 | -0.2 | 0.1 | 0.6 | 0.2 | 0.4 | 0.6 | -0.3 | 0.4 | 0.1 | 0.1 | 0.4 | -0.1 | 0.1 | 0.4 | -0.1 | -0.1 | 0.1 | 0.1 | -0.6 | 0.1 |
Progressive ratio test 1 breakpoint | 0.0 | 0.0 | 0.6 | -0.3 | -0.4 | -0.1 | -0.2 | -0.3 | 0.1 | 0.1 | -0.1 | -0.2 | -0.2 | -0.2 | -0.2 | 0.1 | -0.1 | -0.2 | 0.1 | -0.1 | 0.1 | -0.1 | -0.4 | -0.1 | 0.8 | -0.2 | 0.1 | -0.4 | -0.1 | -0.1 | -0.2 | 0.0 | -0.0 | -0.2 | 0.1 | 0.1 | 0.1 | -0.1 | 0.2 | -0.1 |
Locomotion velocity, session 2 | 0.0 | 0.0 | 0.1 | 0.2 | 0.3 | -0.1 | 0.3 | 0.1 | 0.2 | -0.3 | -0.2 | 0.3 | -0.2 | 0.1 | 0.3 | -0.2 | -0.1 | 0.3 | 0.2 | -0.2 | 0.2 | -0.2 | 0.2 | -0.1 | 0.1 | 0.1 | 0.1 | -0.1 | -0.2 | -0.2 | -0.0 | 0.2 | -0.2 | -0.1 | 0.2 | 0.2 | -0.2 | -0.2 | -0.0 | -0.2 |
Locomotion distance, session 7 | 0.0 | 0.0 | 0.2 | -0.5 | -0.1 | -0.2 | -0.0 | -0.4 | 0.0 | 0.0 | -0.0 | -0.0 | -0.0 | -0.4 | -0.0 | -0.1 | -0.1 | -0.0 | 0.1 | -0.0 | 0.0 | -0.0 | -0.5 | -0.2 | -0.3 | -0.5 | 0.2 | -0.2 | -0.0 | -0.0 | -0.3 | -0.0 | -0.0 | -0.2 | 0.0 | 0.0 | 0.1 | -0.0 | 0.4 | -0.0 |
Novel to familiar place preference ratio | 0.0 | 0.0 | 0.1 | 0.3 | 0.2 | 0.1 | 0.1 | 0.3 | -0.0 | -0.1 | 0.0 | 0.1 | 0.1 | 0.3 | 0.1 | -0.0 | 0.1 | 0.1 | -0.1 | 0.0 | -0.1 | 0.0 | 0.3 | 0.1 | 0.1 | 0.3 | -0.1 | 0.2 | 0.0 | 0.0 | 0.2 | -0.0 | 0.0 | 0.2 | -0.0 | -0.0 | -0.1 | 0.0 | -0.3 | 0.0 |
Novelty place preference | 0.0 | 0.0 | 0.1 | 0.3 | 0.1 | 0.1 | 0.1 | 0.3 | -0.0 | -0.1 | 0.0 | 0.1 | 0.1 | 0.3 | 0.1 | -0.0 | 0.1 | 0.1 | -0.1 | 0.0 | -0.1 | 0.0 | 0.3 | 0.1 | 0.1 | 0.3 | -0.1 | 0.2 | 0.0 | 0.0 | 0.2 | -0.0 | 0.0 | 0.2 | -0.0 | -0.0 | -0.1 | 0.0 | -0.3 | 0.0 |
Bone: final force | 0.0 | 0.0 | 0.2 | -0.2 | -0.0 | -0.1 | -0.1 | -0.3 | 0.1 | 0.0 | -0.1 | -0.1 | -0.1 | -0.2 | -0.1 | 0.0 | -0.1 | -0.1 | 0.1 | -0.2 | 0.1 | -0.2 | -0.2 | -0.1 | 0.5 | -0.2 | 0.1 | -0.2 | -0.1 | -0.1 | -0.2 | 0.1 | -0.1 | -0.2 | 0.1 | 0.1 | 0.0 | -0.1 | 0.2 | -0.1 |
Bone: final moment | 0.0 | 0.0 | 0.3 | 0.0 | 0.2 | -0.2 | 0.1 | -0.1 | 0.2 | -0.1 | -0.3 | 0.1 | -0.2 | -0.0 | 0.1 | -0.1 | -0.2 | 0.1 | 0.2 | -0.3 | 0.3 | -0.3 | 0.0 | -0.2 | 0.6 | -0.0 | 0.2 | -0.2 | -0.3 | -0.3 | -0.2 | 0.2 | -0.2 | -0.2 | 0.2 | 0.3 | -0.1 | -0.3 | 0.1 | -0.3 |
Bone: maximum force | 0.0 | 0.0 | 0.3 | 0.1 | 0.2 | -0.2 | 0.1 | -0.1 | 0.2 | -0.1 | -0.2 | 0.1 | -0.2 | 0.0 | 0.1 | -0.1 | -0.2 | 0.1 | 0.2 | -0.3 | 0.2 | -0.3 | 0.1 | -0.2 | 0.6 | 0.0 | 0.2 | -0.1 | -0.2 | -0.2 | -0.1 | 0.2 | -0.2 | -0.1 | 0.2 | 0.2 | -0.1 | -0.2 | 0.0 | -0.2 |
Bone: post-yield work | 0.0 | 0.0 | 0.2 | 0.5 | 0.2 | -0.0 | 0.2 | 0.5 | 0.1 | -0.2 | -0.1 | 0.2 | -0.2 | 0.4 | 0.2 | -0.1 | -0.0 | 0.2 | 0.0 | -0.2 | 0.1 | -0.2 | 0.5 | -0.0 | 0.1 | 0.4 | -0.0 | 0.0 | -0.1 | -0.1 | 0.2 | 0.2 | -0.2 | 0.1 | 0.1 | 0.1 | -0.1 | -0.1 | -0.3 | -0.1 |
For each tested trait, stats based on TWAS chi2 (squared Z-score) for the above models are shown. Avg chi2 ratio is the mean chi2 across all models for this gene, divided by the mean chi2 across all models for all genes. Avg chi2 is the mean chi2 across all models for this gene. Max chi2 is the highest chi2 across all models for this gene.
The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.